SIMILAR PATTERNS OF AMINO ACIDS FOR 3V3N_D_MIYD2001_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b25 PROTEIN
(FORMALDEHYDE
FERREDOXIN
OXIDOREDUCTASE)

(Pyrococcus
furiosus) 		PF01314
(AFOR_C)
PF02730
(AFOR_N) 		5 HIS A 100
GLY A 157
SER A 176
GLY A  73
ASN A  92
 None
None
None
None
PTT  A 800 (-3.5A)
 1.48A 3v3nD-1b25A:
0.0		 3v3nD-1b25A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e4e VANCOMYCIN/TEICOPLAN
IN A-TYPE RESISTANCE
PROTEIN VANA

(Enterococcus
faecium) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		5 GLY B  12
SER B 102
GLY B 311
ASN B 307
MET B 131
 None
None
PHY  B 355 (-3.3A)
MG  B 360 ( 2.4A)
None
 1.35A 3v3nD-1e4eB:
3.1		 3v3nD-1e4eB:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1flc HAEMAGGLUTININ-ESTER
ASE-FUSION
GLYCOPROTEIN

(Influenza C
virus) 		PF02710
(Hema_HEFG)
PF03996
(Hema_esterase) 		5 PHE A  93
GLY A  94
PHE A 138
ASN A 137
MET A 277
 None
 1.11A 3v3nD-1flcA:
1.2		 3v3nD-1flcA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1opg OPG2 FAB (HEAVY
CHAIN)

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		5 GLN H 117
MET H  34
GLY H 116
GLY H  26
ASN H  77
 None
 1.37A 3v3nD-1opgH:
undetectable		 3v3nD-1opgH:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qgc PROTEIN
(IMMUNOGLOBULIN
HEAVY CHAIN)

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		5 GLN A 112
MET A  34
GLY A 111
GLY A  26
ASN A  77
 None
 1.30A 3v3nD-1qgcA:
undetectable		 3v3nD-1qgcA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sjx IMMUNOGLOBULIN VH
DOMAIN

(Lama glama) 		PF07686
(V-set) 		5 GLN A 911
MET A 834
GLY A 910
GLY A 826
ASN A 876
 None
MPD  A8001 ( 3.5A)
None
None
None
 1.39A 3v3nD-1sjxA:
undetectable		 3v3nD-1sjxA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ty4 APOPTOSIS REGULATOR
CED-9

(Caenorhabditis
elegans) 		PF00452
(Bcl-2)
PF02180
(BH4) 		5 PHE A 123
GLY A 120
SER A 176
PHE A 131
ASN A 130
 None
 1.38A 3v3nD-1ty4A:
0.0		 3v3nD-1ty4A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1via SHIKIMATE KINASE

(Campylobacter
jejuni) 		PF01202
(SKI) 		5 PHE A  84
GLY A  81
SER A  35
PHE A  70
GLY A  94
 None
 1.01A 3v3nD-1viaA:
1.4		 3v3nD-1viaA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vp4 AMINOTRANSFERASE,
PUTATIVE

(Thermotoga
maritima) 		PF00155
(Aminotran_1_2) 		5 GLY A 190
SER A 334
PHE A 384
GLY A  38
MET A 315
 None
None
None
EDO  A 604 ( 3.1A)
None
 1.07A 3v3nD-1vp4A:
0.6		 3v3nD-1vp4A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a5y APOPTOSIS REGULATOR
CED-9

(Caenorhabditis
elegans) 		PF00452
(Bcl-2)
PF02180
(BH4) 		5 PHE A 123
GLY A 120
SER A 176
PHE A 131
ASN A 130
 None
 1.17A 3v3nD-2a5yA:
undetectable		 3v3nD-2a5yA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g9h EXTRACELLULAR
ENTEROTOXIN TYPE I

(Staphylococcus
aureus) 		PF01123
(Stap_Strp_toxin)
PF02876
(Stap_Strp_tox_C) 		5 GLN D 134
PHE D 157
GLY D 141
SER D 159
PHE D 181
 None
 1.50A 3v3nD-2g9hD:
undetectable		 3v3nD-2g9hD:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pgg RNA-DIRECTED RNA
POLYMERASE

(Infectious
bursal disease
virus) 		PF04197
(Birna_RdRp) 		5 HIS A 758
GLY A 445
SER A 442
PHE A 449
ASN A 450
 None
 1.41A 3v3nD-2pggA:
undetectable		 3v3nD-2pggA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wkn FORMAMIDASE

(Delftia
acidovorans) 		PF03069
(FmdA_AmdA) 		5 ARG A 218
GLY A 156
SER A 247
GLY A 211
ASN A  22
 None
 1.29A 3v3nD-2wknA:
undetectable		 3v3nD-2wknA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wzf GLUCOSYLTRANSFERASE

(Legionella
pneumophila) 		PF16849
(Glyco_transf_88) 		5 MET A 269
PHE A 130
GLY A 242
GLY A  89
ASN A 126
 None
 1.15A 3v3nD-2wzfA:
undetectable		 3v3nD-2wzfA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wzg GLUCOSYLTRANSFERASE

(Legionella
pneumophila) 		PF16849
(Glyco_transf_88) 		5 MET A 269
PHE A 130
GLY A 242
GLY A  89
ASN A 126
 None
 1.15A 3v3nD-2wzgA:
undetectable		 3v3nD-2wzgA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3asi NEUREXIN-1-ALPHA

(Bos taurus) 		PF02210
(Laminin_G_2) 		5 GLN A1064
PHE A1068
GLY A1067
GLY A1059
ASN A1083
 None
 1.31A 3v3nD-3asiA:
undetectable		 3v3nD-3asiA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bt6 INFLUENZA B
HEMAGGLUTININ (HA)

(Influenza B
virus) 		PF00509
(Hemagglutinin) 		5 MET A 156
PHE A 152
GLY A 138
SER A 140
PHE A  95
 None
 1.44A 3v3nD-3bt6A:
undetectable		 3v3nD-3bt6A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cdi POLYNUCLEOTIDE
PHOSPHORYLASE

(Escherichia
coli) 		PF01138
(RNase_PH)
PF03725
(RNase_PH_C)
PF03726
(PNPase) 		5 GLY A 459
SER A 457
PHE A 405
GLY A 427
ASN A 404
 None
 1.11A 3v3nD-3cdiA:
undetectable		 3v3nD-3cdiA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gme POLYRIBONUCLEOTIDE
NUCLEOTIDYLTRANSFERA
SE

(Escherichia
coli) 		PF01138
(RNase_PH)
PF03725
(RNase_PH_C)
PF03726
(PNPase) 		5 GLY A 436
SER A 434
PHE A 382
GLY A 404
ASN A 381
 None
 1.16A 3v3nD-3gmeA:
undetectable		 3v3nD-3gmeA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gq9 PRENECK APPENDAGE
PROTEIN

(Bacillus virus
phi29) 		PF11962
(Peptidase_G2)
PF12708
(Pectate_lyase_3) 		5 PHE A 309
GLY A 308
SER A 297
GLY A 350
ASN A 294
 None
 1.45A 3v3nD-3gq9A:
undetectable		 3v3nD-3gq9A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hrr AFLATOXIN
BIOSYNTHESIS
POLYKETIDE SYNTHASE

(Aspergillus
parasiticus) 		PF14765
(PS-DH) 		5 GLN A1547
HIS A1345
PHE A1526
GLY A1529
ASN A1582
 None
HC8  A4000 (-3.5A)
None
None
None
 1.46A 3v3nD-3hrrA:
undetectable		 3v3nD-3hrrA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m49 TRANSKETOLASE

(Bacillus
anthracis) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		5 MET A 161
HIS A  68
GLY A 156
GLY A 193
ASN A 196
 None
TDP  A 701 (-4.0A)
TDP  A 701 ( 3.7A)
None
None
 1.05A 3v3nD-3m49A:
undetectable		 3v3nD-3m49A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m8u HEME-BINDING PROTEIN
A

(Glaesserella
parasuis) 		PF00496
(SBP_bac_5) 		5 HIS A 225
GLY A 205
SER A 183
PHE A 103
MET A 190
 None
 1.21A 3v3nD-3m8uA:
undetectable		 3v3nD-3m8uA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m8y PHOSPHOPENTOMUTASE

(Bacillus cereus) 		PF01676
(Metalloenzyme) 		5 HIS A 328
GLY A  88
PHE A 279
GLY A 239
MET A 225
 MN  A 396 (-3.3A)
TPO  A  85 ( 3.8A)
None
None
None
 1.20A 3v3nD-3m8yA:
undetectable		 3v3nD-3m8yA:
24.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3p9u TETX2 PROTEIN

(Bacteroides
thetaiotaomicron) 		PF01494
(FAD_binding_3) 		7 ARG A 213
HIS A 234
GLY A 236
SER A 238
PHE A 319
GLY A 321
ASN A 371
 SO4  A   1 (-4.5A)
SO4  A   1 ( 4.6A)
None
None
None
None
None
 0.82A 3v3nD-3p9uA:
58.2		 3v3nD-3p9uA:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3p9u TETX2 PROTEIN

(Bacteroides
thetaiotaomicron) 		PF01494
(FAD_binding_3) 		7 ARG A 213
HIS A 234
GLY A 236
SER A 238
PHE A 319
GLY A 321
MET A 375
 SO4  A   1 (-4.5A)
SO4  A   1 ( 4.6A)
None
None
None
None
None
 0.67A 3v3nD-3p9uA:
58.2		 3v3nD-3p9uA:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3p9u TETX2 PROTEIN

(Bacteroides
thetaiotaomicron) 		PF01494
(FAD_binding_3) 		7 ARG A 213
MET A 215
HIS A 234
GLY A 236
SER A 238
PHE A 319
ASN A 371
 SO4  A   1 (-4.5A)
None
SO4  A   1 ( 4.6A)
None
None
None
None
 0.86A 3v3nD-3p9uA:
58.2		 3v3nD-3p9uA:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3p9u TETX2 PROTEIN

(Bacteroides
thetaiotaomicron) 		PF01494
(FAD_binding_3) 		7 ARG A 213
MET A 215
HIS A 234
GLY A 236
SER A 238
PHE A 319
MET A 375
 SO4  A   1 (-4.5A)
None
SO4  A   1 ( 4.6A)
None
None
None
None
 0.57A 3v3nD-3p9uA:
58.2		 3v3nD-3p9uA:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3p9u TETX2 PROTEIN

(Bacteroides
thetaiotaomicron) 		PF01494
(FAD_binding_3) 		7 GLN A 192
ARG A 213
HIS A 234
SER A 238
PHE A 319
GLY A 321
ASN A 371
 FAD  A 401 (-3.4A)
SO4  A   1 (-4.5A)
SO4  A   1 ( 4.6A)
None
None
None
None
 0.99A 3v3nD-3p9uA:
58.2		 3v3nD-3p9uA:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3p9u TETX2 PROTEIN

(Bacteroides
thetaiotaomicron) 		PF01494
(FAD_binding_3) 		7 GLN A 192
ARG A 213
HIS A 234
SER A 238
PHE A 319
GLY A 321
MET A 375
 FAD  A 401 (-3.4A)
SO4  A   1 (-4.5A)
SO4  A   1 ( 4.6A)
None
None
None
None
 0.88A 3v3nD-3p9uA:
58.2		 3v3nD-3p9uA:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3p9u TETX2 PROTEIN

(Bacteroides
thetaiotaomicron) 		PF01494
(FAD_binding_3) 		7 GLN A 192
ARG A 213
MET A 215
HIS A 234
SER A 238
PHE A 319
ASN A 371
 FAD  A 401 (-3.4A)
SO4  A   1 (-4.5A)
None
SO4  A   1 ( 4.6A)
None
None
None
 1.01A 3v3nD-3p9uA:
58.2		 3v3nD-3p9uA:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3p9u TETX2 PROTEIN

(Bacteroides
thetaiotaomicron) 		PF01494
(FAD_binding_3) 		7 GLN A 192
ARG A 213
MET A 215
HIS A 234
SER A 238
PHE A 319
MET A 375
 FAD  A 401 (-3.4A)
SO4  A   1 (-4.5A)
None
SO4  A   1 ( 4.6A)
None
None
None
 0.79A 3v3nD-3p9uA:
58.2		 3v3nD-3p9uA:
99.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pow CALRETICULIN

(Homo sapiens) 		PF00262
(Calreticulin) 		5 GLN A 320
HIS A  99
GLY A 107
PHE A  49
GLY A  65
 None
None
None
None
CA  A 900 ( 4.9A)
 1.49A 3v3nD-3powA:
undetectable		 3v3nD-3powA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qmw THIOESTERASE

(Streptomyces
coelicolor) 		PF00975
(Thioesterase) 		5 GLY A 105
SER A 134
PHE A 243
GLY A 246
ASN A 240
 None
 1.24A 3v3nD-3qmwA:
undetectable		 3v3nD-3qmwA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3suc PRENECK APPENDAGE
PROTEIN

(Bacillus virus
phi29) 		PF11962
(Peptidase_G2)
PF12708
(Pectate_lyase_3) 		5 PHE A 309
GLY A 308
SER A 297
GLY A 350
ASN A 294
 None
 1.44A 3v3nD-3sucA:
undetectable		 3v3nD-3sucA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zq4 RIBONUCLEASE J 1

(Bacillus
subtilis) 		PF00753
(Lactamase_B)
PF07521
(RMMBL) 		5 PHE A 137
HIS A 161
GLY A 149
GLY A  69
ASN A 120
 None
 1.27A 3v3nD-3zq4A:
undetectable		 3v3nD-3zq4A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4am3 POLYRIBONUCLEOTIDE
NUCLEOTIDYLTRANSFERA
SE

(Caulobacter
vibrioides) 		PF00013
(KH_1)
PF01138
(RNase_PH)
PF03725
(RNase_PH_C)
PF03726
(PNPase) 		5 GLY A 438
SER A 436
PHE A 384
GLY A 406
ASN A 383
 PO4  A1622 (-3.9A)
PO4  A1622 (-3.1A)
None
None
None
 1.20A 3v3nD-4am3A:
undetectable		 3v3nD-4am3A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e7w GLYCOGEN SYNTHASE
KINASE 3

(Ustilago maydis) 		PF00069
(Pkinase) 		5 ARG A 161
HIS A 154
GLY A 157
GLY A 183
ASN A  76
 None
 1.49A 3v3nD-4e7wA:
undetectable		 3v3nD-4e7wA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e8d GLYCOSYL HYDROLASE,
FAMILY 35

(Streptococcus
pneumoniae) 		PF01301
(Glyco_hydro_35) 		5 PHE A 459
HIS A 457
PHE A 101
GLY A 288
ASN A  56
 None
 1.29A 3v3nD-4e8dA:
1.4		 3v3nD-4e8dA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ly4 PEPTIDOGLYCAN
DEACETYLASE

(Helicobacter
pylori) 		PF01522
(Polysacc_deac_1) 		5 HIS A 247
SER A 243
PHE A 278
GLY A  84
ASN A 279
 None
 1.49A 3v3nD-4ly4A:
undetectable		 3v3nD-4ly4A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nbq POLYRIBONUCLEOTIDE
NUCLEOTIDYLTRANSFERA
SE

(Coxiella
burnetii) 		PF00013
(KH_1)
PF00575
(S1)
PF01138
(RNase_PH)
PF03725
(RNase_PH_C)
PF03726
(PNPase) 		5 GLY A 439
SER A 437
PHE A 385
GLY A 407
ASN A 384
 SO4  A 701 (-4.2A)
SO4  A 701 (-2.9A)
None
None
None
 1.15A 3v3nD-4nbqA:
undetectable		 3v3nD-4nbqA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rih GLYCOSYL TRANSFERASE
HOMOLOG,GLYCOSYL
TRANSFERASE

(Streptomyces
cyanogenus;
Streptomyces
fradiae) 		PF06722
(DUF1205) 		5 MET A 116
PHE A  88
HIS A  86
GLY A  89
GLY A 306
 None
 1.41A 3v3nD-4rihA:
3.0		 3v3nD-4rihA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rku PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT V,
CHLOROPLASTIC

(Pisum sativum) 		PF00223
(PsaA_PsaB)
PF01241
(PSI_PSAK) 		5 GLN G  94
ARG G 107
GLY G  98
GLY B 298
ASN B 176
 None
None
None
CLA  B1218 (-3.8A)
None
 1.49A 3v3nD-4rkuG:
undetectable		 3v3nD-4rkuG:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5efn HDAC6 PROTEIN

(Danio rerio) 		no annotation 5 PHE B 583
HIS B 573
GLY B 582
SER B 531
GLY B 713
 None
 1.40A 3v3nD-5efnB:
undetectable		 3v3nD-5efnB:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jay 8-AMINO-7-OXONONANOA
TE SYNTHASE

(Paraburkholderia
xenovorans) 		PF00155
(Aminotran_1_2) 		5 PHE A 213
HIS A 211
GLY A 212
PHE A 250
GLY A 248
 None
 1.28A 3v3nD-5jayA:
undetectable		 3v3nD-5jayA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jft CASPASE 3,
APOPTOSIS-RELATED
CYSTEINE PROTEASE A

(Danio rerio) 		PF00656
(Peptidase_C14) 		5 MET A 278
PHE A 280
GLY A 232
PHE A  81
GLY A  48
 None
 1.33A 3v3nD-5jftA:
3.7		 3v3nD-5jftA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xct VH(S112C)-SARAH
CHIMERA
VL-SARAH(S37C)CHIMER
A

(Homo sapiens;
Mus musculus) 		PF07686
(V-set)
PF11629
(Mst1_SARAH) 		5 GLN B   6
PHE B  98
GLY B  99
SER A  44
GLY B  46
 None
 1.14A 3v3nD-5xctB:
undetectable		 3v3nD-5xctB:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d6k POLYRIBONUCLEOTIDE
NUCLEOTIDYLTRANSFERA
SE

(Acinetobacter
baumannii) 		no annotation 5 GLY A 438
SER A 436
PHE A 384
GLY A 406
ASN A 383
 None
 1.22A 3v3nD-6d6kA:
undetectable		 3v3nD-6d6kA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fzw COLLAGEN
ALPHA-1(III) CHAIN

(Homo sapiens) 		no annotation 5 PHE A 235
HIS A 150
GLY A 236
PHE A 107
MET A 111
 None
 1.35A 3v3nD-6fzwA:
undetectable		 3v3nD-6fzwA:
10.81