SIMILAR PATTERNS OF AMINO ACIDS FOR 3V3N_B_MIYB2001

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bu8 PROTEIN (PANCREATIC
LIPASE RELATED
PROTEIN 2)


(Rattus
norvegicus)
PF00151
(Lipase)
PF01477
(PLAT)
4 PHE A 215
GLY A 214
GLY A 254
ASN A 249
None
0.93A 3v3nB-1bu8A:
undetectable
3v3nB-1bu8A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bxz NADP-DEPENDENT
ALCOHOL
DEHYDROGENASE


(Thermoanaerobacter
brockii)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 PHE A 268
HIS A  42
GLY A 269
GLY A 174
None
0.94A 3v3nB-1bxzA:
undetectable
3v3nB-1bxzA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h39 SQUALENE--HOPENE
CYCLASE


(Alicyclobacillus
acidocaldarius)
PF13243
(SQHop_cyclase_C)
PF13249
(SQHop_cyclase_N)
4 GLN A 366
GLY A 260
GLY A 600
MET A  42
None
None
None
R03  A 800 ( 4.9A)
0.90A 3v3nB-1h39A:
undetectable
3v3nB-1h39A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jne IMAGINAL DISC GROWTH
FACTOR-2


(Drosophila
melanogaster)
PF00704
(Glyco_hydro_18)
4 PHE A 267
GLY A 266
GLY A 389
ASN A 218
None
0.90A 3v3nB-1jneA:
undetectable
3v3nB-1jneA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m72 CASPASE-1

(Spodoptera
frugiperda)
PF00656
(Peptidase_C14)
4 ARG A  79
HIS A  70
GLY A 229
ASN A  88
None
0.98A 3v3nB-1m72A:
3.8
3v3nB-1m72A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n5x XANTHINE
DEHYDROGENASE


(Bos taurus)
PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C)
4 GLN A 918
PHE A 914
GLY A 915
GLY A 800
None
TEI  A3006 (-3.6A)
None
None
0.83A 3v3nB-1n5xA:
undetectable
3v3nB-1n5xA:
14.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p3c GLUTAMYL-ENDOPEPTIDA
SE


(Bacillus
intermedius)
PF00089
(Trypsin)
4 PHE A  27
GLY A  61
GLY A 169
ASN A  45
None
0.96A 3v3nB-1p3cA:
undetectable
3v3nB-1p3cA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p4i ANTIBODY VARIABLE
LIGHT CHAIN


(Mus musculus)
PF07686
(V-set)
4 GLN L   6
PHE L 139
GLY L 140
GLY L  57
None
0.91A 3v3nB-1p4iL:
undetectable
3v3nB-1p4iL:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)


(Synechococcus
elongatus)
PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N)
4 GLY A 166
GLY A 196
ASN A 420
MET A 387
None
0.97A 3v3nB-1rblA:
2.1
3v3nB-1rblA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1svd RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT


(Halothiobacillus
neapolitanus)
PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N)
4 GLY A 159
GLY A 189
ASN A 413
MET A 380
None
0.88A 3v3nB-1svdA:
undetectable
3v3nB-1svdA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wra TEICHOIC ACID
PHOSPHORYLCHOLINE
ESTERASE/CHOLINE
BINDING PROTEIN E
(CBPE)


(Streptococcus
pneumoniae)
PF00753
(Lactamase_B)
4 HIS A 110
GLY A 227
GLY A  41
ASN A 304
FE  A 401 (-3.5A)
None
None
None
0.98A 3v3nB-1wraA:
undetectable
3v3nB-1wraA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x1n 4-ALPHA-GLUCANOTRANS
FERASE


(Solanum
tuberosum)
PF02446
(Glyco_hydro_77)
4 PHE A 329
HIS A 322
GLY A 325
GLY A 342
None
0.91A 3v3nB-1x1nA:
undetectable
3v3nB-1x1nA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xzw PURPLE ACID
PHOSPHATASE


(Ipomoea batatas)
PF00149
(Metallophos)
PF14008
(Metallophos_C)
PF16656
(Pur_ac_phosph_N)
4 HIS A  29
GLY A 182
GLY A 162
ASN A 363
None
None
None
FE  A 429 ( 4.3A)
0.91A 3v3nB-1xzwA:
undetectable
3v3nB-1xzwA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yif BETA-1,4-XYLOSIDASE

(Bacillus
subtilis)
PF04616
(Glyco_hydro_43)
4 ARG A 207
HIS A 210
GLY A 502
ASN A 413
None
0.95A 3v3nB-1yifA:
undetectable
3v3nB-1yifA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zvf 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE


(Saccharomyces
cerevisiae)
PF06052
(3-HAO)
4 ARG A 114
GLY A  32
GLY A 144
ASN A  26
None
1.00A 3v3nB-1zvfA:
undetectable
3v3nB-1zvfA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bac PUTATIVE
AMINOOXIDASE


(Cutibacterium
acnes)
PF01593
(Amino_oxidase)
4 PHE A 168
GLY A 169
GLY A 296
MET A  62
ODT  A1001 (-3.7A)
None
None
ODT  A1001 ( 3.9A)
0.87A 3v3nB-2bacA:
16.1
3v3nB-2bacA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bib TEICHOIC ACID
PHOSPHORYLCHOLINE
ESTERASE/ CHOLINE
BINDING PROTEIN


(Streptococcus
pneumoniae)
PF00753
(Lactamase_B)
PF01473
(CW_binding_1)
4 HIS A  85
GLY A 202
GLY A  16
ASN A 279
ZN  A1550 (-3.3A)
None
None
None
0.95A 3v3nB-2bibA:
undetectable
3v3nB-2bibA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dws COPPER-CONTAINING
NITRITE REDUCTASE


(Rhodobacter
sphaeroides)
PF00394
(Cu-oxidase)
PF07732
(Cu-oxidase_3)
4 HIS A 215
GLY A 181
GLY A 234
MET A 124
None
0.90A 3v3nB-2dwsA:
undetectable
3v3nB-2dwsA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hj9 AUTOINDUCER
2-BINDING
PERIPLASMIC PROTEIN
LUXP


(Vibrio harveyi)
PF13407
(Peripla_BP_4)
4 PHE A 178
HIS A 180
GLY A 177
GLY A 291
None
0.97A 3v3nB-2hj9A:
3.0
3v3nB-2hj9A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hlp MALATE DEHYDROGENASE

(Haloarcula
marismortui)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
4 PHE A 163
GLY A 162
GLY A  33
ASN A  39
None
0.92A 3v3nB-2hlpA:
4.0
3v3nB-2hlpA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pyh POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE 4


(Azotobacter
vinelandii)
PF12708
(Pectate_lyase_3)
4 PHE A 198
GLY A 197
GLY A 241
ASN A 187
None
0.99A 3v3nB-2pyhA:
undetectable
3v3nB-2pyhA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w8s PHOSPHONATE
MONOESTER HYDROLASE


(Paraburkholderia
caryophylli)
PF00884
(Sulfatase)
PF16347
(DUF4976)
4 PHE A  47
GLY A 366
GLY A 361
ASN A 357
None
0.99A 3v3nB-2w8sA:
undetectable
3v3nB-2w8sA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x7i MEVALONATE KINASE

(Staphylococcus
aureus)
PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C)
4 PHE A 231
HIS A 235
GLY A 263
GLY A  17
None
0.80A 3v3nB-2x7iA:
undetectable
3v3nB-2x7iA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xn8 PUTATIVE CYTOCHROME
P450 125


(Mycobacterium
tuberculosis)
PF00067
(p450)
4 GLN A  57
PHE A  65
GLY A  62
GLY A 334
None
0.85A 3v3nB-2xn8A:
undetectable
3v3nB-2xn8A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y24 XYLANASE

(Dickeya
chrysanthemi)
PF02055
(Glyco_hydro_30)
PF17189
(Glyco_hydro_30C)
4 PHE A  47
GLY A  48
GLY A 321
MET A 279
None
0.71A 3v3nB-2y24A:
undetectable
3v3nB-2y24A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y24 XYLANASE

(Dickeya
chrysanthemi)
PF02055
(Glyco_hydro_30)
PF17189
(Glyco_hydro_30C)
4 PHE A 182
GLY A 179
GLY A 229
ASN A 164
None
None
None
XYP  A1001 (-3.1A)
0.99A 3v3nB-2y24A:
undetectable
3v3nB-2y24A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yhe SEC-ALKYL SULFATASE

(Pseudomonas sp.
DSM 6611)
PF00753
(Lactamase_B)
PF14863
(Alkyl_sulf_dimr)
PF14864
(Alkyl_sulf_C)
4 ARG A 227
GLY A 234
GLY A 531
MET A 505
None
0.78A 3v3nB-2yheA:
undetectable
3v3nB-2yheA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yp1 AROMATIC
PEROXYGENASE


(Agrocybe
aegerita)
PF01328
(Peroxidase_2)
4 PHE A  76
GLY A 314
GLY A 195
MET A 280
None
0.87A 3v3nB-2yp1A:
undetectable
3v3nB-2yp1A:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ztg ALANYL-TRNA
SYNTHETASE


(Archaeoglobus
fulgidus)
PF01411
(tRNA-synt_2c)
PF07973
(tRNA_SAD)
4 GLN A 105
ARG A 128
GLY A 194
GLY A 244
None
A5A  A 801 (-2.7A)
None
A5A  A 801 (-4.0A)
0.65A 3v3nB-2ztgA:
undetectable
3v3nB-2ztgA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zzg ALANYL-TRNA
SYNTHETASE


(Pyrococcus
horikoshii)
PF01411
(tRNA-synt_2c)
PF07973
(tRNA_SAD)
4 GLN A 105
ARG A 128
GLY A 195
GLY A 250
None
A5A  A 999 (-3.0A)
None
A5A  A 999 (-3.5A)
0.49A 3v3nB-2zzgA:
undetectable
3v3nB-2zzgA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cpg UNCHARACTERIZED
PROTEIN


(Bifidobacterium
adolescentis)
PF01168
(Ala_racemase_N)
4 ARG A 262
GLY A 200
GLY A 205
ASN A 168
None
0.98A 3v3nB-3cpgA:
undetectable
3v3nB-3cpgA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fah ALDEHYDE
OXIDOREDUCTASE


(Desulfovibrio
gigas)
PF00111
(Fer2)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
4 PHE A 494
GLY A 495
GLY A 422
MET A 398
None
None
PCD  A 921 (-3.4A)
None
0.95A 3v3nB-3fahA:
undetectable
3v3nB-3fahA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h5l PUTATIVE
BRANCHED-CHAIN AMINO
ACID ABC TRANSPORTER


(Ruegeria
pomeroyi)
PF13458
(Peripla_BP_6)
4 GLN A 261
GLY A 282
GLY A 202
ASN A 207
None
0.85A 3v3nB-3h5lA:
2.1
3v3nB-3h5lA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i04 CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT BETA


(Moorella
thermoacetica)
PF03063
(Prismane)
4 PHE A 527
GLY A 526
GLY A 463
ASN A 453
None
0.92A 3v3nB-3i04A:
3.2
3v3nB-3i04A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jyo QUINATE/SHIKIMATE
DEHYDROGENASE


(Corynebacterium
glutamicum)
PF08501
(Shikimate_dh_N)
4 PHE A 114
HIS A 257
GLY A 117
ASN A 200
None
0.98A 3v3nB-3jyoA:
4.1
3v3nB-3jyoA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kl0 GLUCURONOXYLANASE
XYNC


(Bacillus
subtilis)
PF17189
(Glyco_hydro_30C)
4 PHE A  19
GLY A  20
GLY A 300
MET A 257
None
0.76A 3v3nB-3kl0A:
undetectable
3v3nB-3kl0A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lfu DNA HELICASE II

(Escherichia
coli)
PF00580
(UvrD-helicase)
PF13361
(UvrD_C)
4 ARG A 140
GLY A 489
GLY A 502
ASN A 508
None
0.68A 3v3nB-3lfuA:
undetectable
3v3nB-3lfuA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oja LEUCINE-RICH IMMUNE
MOLECULE 1


(Anopheles
gambiae)
PF00560
(LRR_1)
4 GLN A 209
PHE A 183
GLY A 208
GLY A 237
None
0.93A 3v3nB-3ojaA:
undetectable
3v3nB-3ojaA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3om5 LEVANSUCRASE

(Bacillus
megaterium)
PF02435
(Glyco_hydro_68)
4 GLN A 100
HIS A 259
GLY A 104
ASN A 433
None
0.97A 3v3nB-3om5A:
undetectable
3v3nB-3om5A:
23.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3p9u TETX2 PROTEIN

(Bacteroides
thetaiotaomicron)
PF01494
(FAD_binding_3)
4 ARG A 213
HIS A 234
GLY A 236
GLY A 321
SO4  A   1 (-4.5A)
SO4  A   1 ( 4.6A)
None
None
0.42A 3v3nB-3p9uA:
58.4
3v3nB-3p9uA:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3p9u TETX2 PROTEIN

(Bacteroides
thetaiotaomicron)
PF01494
(FAD_binding_3)
4 ARG A 213
HIS A 234
GLY A 236
MET A 375
SO4  A   1 (-4.5A)
SO4  A   1 ( 4.6A)
None
None
0.46A 3v3nB-3p9uA:
58.4
3v3nB-3p9uA:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3p9u TETX2 PROTEIN

(Bacteroides
thetaiotaomicron)
PF01494
(FAD_binding_3)
4 ARG A 213
HIS A 234
GLY A 321
ASN A 371
SO4  A   1 (-4.5A)
SO4  A   1 ( 4.6A)
None
None
0.96A 3v3nB-3p9uA:
58.4
3v3nB-3p9uA:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3p9u TETX2 PROTEIN

(Bacteroides
thetaiotaomicron)
PF01494
(FAD_binding_3)
4 GLN A 192
ARG A 213
HIS A 234
GLY A 321
FAD  A 401 (-3.4A)
SO4  A   1 (-4.5A)
SO4  A   1 ( 4.6A)
None
0.89A 3v3nB-3p9uA:
58.4
3v3nB-3p9uA:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3p9u TETX2 PROTEIN

(Bacteroides
thetaiotaomicron)
PF01494
(FAD_binding_3)
4 GLN A 192
ARG A 213
HIS A 234
MET A 375
FAD  A 401 (-3.4A)
SO4  A   1 (-4.5A)
SO4  A   1 ( 4.6A)
None
0.86A 3v3nB-3p9uA:
58.4
3v3nB-3p9uA:
99.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qpc CUTINASE

(Fusarium solani)
PF01083
(Cutinase)
4 PHE A 147
HIS A 188
GLY A 148
GLY A  49
None
MIR  A 120 ( 3.7A)
MIR  A 120 ( 4.2A)
None
0.96A 3v3nB-3qpcA:
undetectable
3v3nB-3qpcA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qpd CUTINASE 1

(Aspergillus
oryzae)
PF01083
(Cutinase)
4 PHE A 153
HIS A 194
GLY A 154
GLY A  55
None
SEP  A 126 ( 4.1A)
SEP  A 126 ( 4.5A)
None
0.98A 3v3nB-3qpdA:
2.9
3v3nB-3qpdA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ri5 MOUSE MONOCLONAL FAB
FRAGMENT, LIGHT
CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 GLN K   6
PHE K 100
GLY K 101
GLY K  51
None
0.89A 3v3nB-3ri5K:
undetectable
3v3nB-3ri5K:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E


(Bos taurus)
PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2)
4 GLN C 918
PHE C 914
GLY C 915
GLY C 800
None
RMO  C1317 (-3.6A)
None
None
0.80A 3v3nB-3sr6C:
undetectable
3v3nB-3sr6C:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t2n ANTIBODY, FAB
FRAGMENT, LIGHT
CHAIN


(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
4 GLN L   6
PHE L  98
GLY L  99
GLY L  49
None
0.99A 3v3nB-3t2nL:
undetectable
3v3nB-3t2nL:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ut2 CATALASE-PEROXIDASE
2


(Magnaporthe
oryzae)
PF00141
(peroxidase)
4 PHE A 741
GLY A 742
GLY A 672
MET A 652
None
0.93A 3v3nB-3ut2A:
undetectable
3v3nB-3ut2A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vab DIAMINOPIMELATE
DECARBOXYLASE 1


(Brucella
melitensis)
PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N)
4 GLN A 204
GLY A 242
GLY A 286
ASN A  63
None
0.93A 3v3nB-3vabA:
undetectable
3v3nB-3vabA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vup BETA-1,4-MANNANASE

(Aplysia kurodai)
PF00150
(Cellulase)
4 PHE A 294
HIS A 262
GLY A 292
ASN A 330
None
None
None
SO4  A 404 (-3.9A)
0.99A 3v3nB-3vupA:
undetectable
3v3nB-3vupA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wqy ALANINE--TRNA LIGASE

(Archaeoglobus
fulgidus)
PF01411
(tRNA-synt_2c)
PF02272
(DHHA1)
PF07973
(tRNA_SAD)
4 GLN A 105
ARG A 128
GLY A 194
GLY A 244
None
A5A  A1001 (-3.4A)
None
A5A  A1001 (-3.7A)
0.53A 3v3nB-3wqyA:
undetectable
3v3nB-3wqyA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zq4 RIBONUCLEASE J 1

(Bacillus
subtilis)
PF00753
(Lactamase_B)
PF07521
(RMMBL)
4 PHE A 137
GLY A 149
GLY A  69
ASN A 120
None
0.92A 3v3nB-3zq4A:
undetectable
3v3nB-3zq4A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyv AOX3

(Mus musculus)
PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C)
4 GLN A 923
PHE A 919
GLY A 920
GLY A 805
None
0.60A 3v3nB-3zyvA:
undetectable
3v3nB-3zyvA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4amm DYNE8

(Micromonospora
chersina)
PF00698
(Acyl_transf_1)
4 ARG A 676
GLY A 804
GLY A 580
MET A 690
None
0.92A 3v3nB-4ammA:
undetectable
3v3nB-4ammA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4at0 3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E


(Rhodococcus
jostii)
PF00890
(FAD_binding_2)
4 GLN A  76
HIS A 166
GLY A  70
GLY A 149
None
0.77A 3v3nB-4at0A:
11.3
3v3nB-4at0A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bwr PROTEIN
CORRESPONDING TO
LOCUS C5321 FROM
CFT073 E.COLI STRAIN


(Escherichia
coli)
PF08238
(Sel1)
4 GLN A  92
ARG A 116
GLY A 126
GLY A 139
None
None
None
EDO  A1487 ( 4.8A)
0.90A 3v3nB-4bwrA:
undetectable
3v3nB-4bwrA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dhe PROBABLE GTP-BINDING
PROTEIN ENGB


(Burkholderia
thailandensis)
PF01926
(MMR_HSR1)
4 GLN A 184
GLY A 193
GLY A  37
ASN A  43
None
None
CL  A 303 ( 3.7A)
None
0.98A 3v3nB-4dheA:
undetectable
3v3nB-4dheA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4evz HISF-LUCA

(synthetic
construct)
PF00977
(His_biosynth)
4 GLN A 123
PHE A 120
GLY A 121
GLY A  96
None
0.99A 3v3nB-4evzA:
undetectable
3v3nB-4evzA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE


([Clostridium]
papyrosolvens)
PF02055
(Glyco_hydro_30)
PF17189
(Glyco_hydro_30C)
4 PHE A  19
GLY A  20
GLY A 297
MET A 254
None
0.70A 3v3nB-4fmvA:
undetectable
3v3nB-4fmvA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ihe THNT PROTEIN

(Streptomyces
cattleya)
PF03576
(Peptidase_S58)
4 GLN A 179
ARG A 370
GLY A 198
GLY A  30
None
0.92A 3v3nB-4iheA:
undetectable
3v3nB-4iheA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jc8 HOPS COMPONENT VPS33

(Chaetomium
thermophilum)
PF00995
(Sec1)
4 ARG A 621
PHE A 614
GLY A 254
GLY A 304
None
0.88A 3v3nB-4jc8A:
undetectable
3v3nB-4jc8A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN


(Pisum sativum)
PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N)
4 GLY A 166
GLY A 196
ASN A 420
MET A 387
None
0.93A 3v3nB-4mkvA:
undetectable
3v3nB-4mkvA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mnr PEPTIDOGLYCAN
GLYCOSYLTRANSFERASE


(Eggerthella
lenta)
PF00905
(Transpeptidase)
4 PHE A 184
GLY A 181
GLY A 246
MET A 278
None
0.95A 3v3nB-4mnrA:
undetectable
3v3nB-4mnrA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pfw ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN


(Thermotoga
maritima)
PF00496
(SBP_bac_5)
4 GLN A 521
GLY A 241
GLY A  32
ASN A 231
None
None
None
BMA  A 607 ( 2.7A)
0.93A 3v3nB-4pfwA:
undetectable
3v3nB-4pfwA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pj3 INTRON-BINDING
PROTEIN AQUARIUS


(Homo sapiens)
PF13086
(AAA_11)
PF13087
(AAA_12)
PF16399
(Aquarius_N)
4 GLN A1136
GLY A1137
GLY A1300
ASN A1268
None
ANP  A1501 ( 3.8A)
None
None
0.76A 3v3nB-4pj3A:
undetectable
3v3nB-4pj3A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qaw XYN30D

(Paenibacillus
barcinonensis)
PF03422
(CBM_6)
PF17189
(Glyco_hydro_30C)
4 PHE A  18
GLY A  19
GLY A 299
MET A 256
None
0.73A 3v3nB-4qawA:
undetectable
3v3nB-4qawA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qbu ZMAA

(Bacillus cereus)
PF00698
(Acyl_transf_1)
4 ARG A 217
GLY A 350
GLY A 101
MET A 229
FMT  A 500 (-2.9A)
None
None
None
0.66A 3v3nB-4qbuA:
undetectable
3v3nB-4qbuA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r7k HYPOTHETICAL PROTEIN
JHP0584


(Helicobacter
pylori)
no annotation 4 PHE A  79
GLY A  78
GLY A 101
MET A 151
None
0.95A 3v3nB-4r7kA:
2.3
3v3nB-4r7kA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ra7 PEPTIDOGLYCAN
GLYCOSYLTRANSFERASE


(Atopobium
parvulum)
PF00905
(Transpeptidase)
4 PHE A 684
GLY A 681
GLY A 746
MET A 778
None
NXU  A1001 ( 4.0A)
None
None
0.94A 3v3nB-4ra7A:
undetectable
3v3nB-4ra7A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x28 ACYL-COA
DEHYDROGENASE


(Mycobacterium
tuberculosis)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
no annotation
4 GLN D 349
GLY D 192
GLY A 362
ASN A 354
None
0.84A 3v3nB-4x28D:
undetectable
3v3nB-4x28D:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x8d SULFOXIDE SYNTHASE
EGTB


(Mycolicibacterium
thermoresistibile)
PF03781
(FGE-sulfatase)
PF12867
(DinB_2)
4 GLN A 230
PHE A 222
GLY A 226
GLY A 290
None
None
None
GOL  A 504 (-3.2A)
0.96A 3v3nB-4x8dA:
undetectable
3v3nB-4x8dA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E


(Rattus
norvegicus)
PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C)
4 GLN A 918
PHE A 914
GLY A 915
GLY A 800
BCT  A3006 (-3.0A)
URC  A3007 ( 3.4A)
BCT  A3006 (-3.9A)
None
0.75A 3v3nB-4yswA:
undetectable
3v3nB-4yswA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zm4 AMINOTRANSFERASE

(Streptomyces
pactum)
PF00202
(Aminotran_3)
4 PHE A 419
HIS A  67
GLY A  63
GLY A 253
None
0.81A 3v3nB-4zm4A:
undetectable
3v3nB-4zm4A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a2k IG LAMBDA-1 CHAIN V
REGION S43


(Mus musculus)
PF07686
(V-set)
4 GLN H1007
PHE H1098
GLY H1099
GLY H1049
None
None
None
EDO  H3005 ( 4.7A)
0.87A 3v3nB-5a2kH:
undetectable
3v3nB-5a2kH:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ajh CUTINASE

(Fusarium
oxysporum)
PF01083
(Cutinase)
4 PHE A 148
HIS A 189
GLY A 149
GLY A  50
None
MPD  A1221 (-4.0A)
None
None
0.88A 3v3nB-5ajhA:
2.8
3v3nB-5ajhA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bnz GLUTAMINE--TRNA
LIGASE


(Pseudomonas
aeruginosa)
PF00749
(tRNA-synt_1c)
PF03950
(tRNA-synt_1c_C)
4 GLN A  77
PHE A  67
HIS A 201
GLY A  39
None
0.96A 3v3nB-5bnzA:
undetectable
3v3nB-5bnzA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cxp POSSIBLE XYLAN
DEGRADATION ENZYME
(GLYCOSYL HYDROLASE
FAMILY 30-LIKE
DOMAIN AND RICIN
B-LIKE DOMAIN)


(Clostridium
acetobutylicum)
PF02055
(Glyco_hydro_30)
4 PHE A  20
GLY A  21
GLY A 297
MET A 252
None
0.84A 3v3nB-5cxpA:
undetectable
3v3nB-5cxpA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1


(Arabidopsis
thaliana)
PF03321
(GH3)
4 GLN A 560
PHE A 113
GLY A 163
ASN A 174
None
0.95A 3v3nB-5ecoA:
undetectable
3v3nB-5ecoA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ehk LANTIBIOTIC
DEHYDRATASE


(Microbispora
corallina)
PF04738
(Lant_dehydr_N)
PF14028
(Lant_dehydr_C)
4 GLN A 556
HIS A 533
GLY A 535
GLY A 292
None
0.91A 3v3nB-5ehkA:
undetectable
3v3nB-5ehkA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5epg ALDEHYDE OXIDASE

(Homo sapiens)
PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C)
4 GLN A 927
PHE A 923
GLY A 924
GLY A 809
None
MOS  A3005 (-4.2A)
None
None
0.62A 3v3nB-5epgA:
undetectable
3v3nB-5epgA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f75 THIOCYANATE
DEHYDROGENASE


(Thioalkalivibrio
paradoxus)
no annotation 4 GLN A 501
HIS A 528
GLY A 526
GLY A 478
None
CU  A 602 (-3.0A)
None
None
0.95A 3v3nB-5f75A:
undetectable
3v3nB-5f75A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fcs DIABODY

(Homo sapiens)
PF07686
(V-set)
4 GLN H   6
PHE H 100
GLY H 101
GLY H  51
None
0.86A 3v3nB-5fcsH:
undetectable
3v3nB-5fcsH:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fhz ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3


(Homo sapiens)
PF00171
(Aldedh)
4 PHE A 144
HIS A 101
GLY A 146
GLY A 136
None
None
None
REA  A 602 (-3.4A)
0.73A 3v3nB-5fhzA:
1.5
3v3nB-5fhzA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fur TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 2


(Homo sapiens)
no annotation 4 ARG I 361
PHE I 503
GLY I 502
MET I 469
None
0.93A 3v3nB-5furI:
undetectable
3v3nB-5furI:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hee PUTATIVE
UNCHARACTERIZED
PROTEIN, TK2203
PROTEIN


(Thermococcus
kodakarensis)
PF02900
(LigB)
4 PHE A 252
HIS A 173
GLY A 253
GLY A 120
None
0.96A 3v3nB-5heeA:
undetectable
3v3nB-5heeA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ijl DNA POLYMERASE II
LARGE SUBUNIT


(Pyrococcus
abyssi)
PF03833
(PolC_DP2)
4 PHE A 704
HIS A 711
GLY A 713
GLY A  32
None
0.71A 3v3nB-5ijlA:
undetectable
3v3nB-5ijlA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ikg DYE-DECOLORIZING
PEROXIDASE


(Auricularia
auricula-judae)
PF04261
(Dyp_perox)
4 GLN A 424
GLY A 403
GLY A 393
ASN A 380
None
0.86A 3v3nB-5ikgA:
undetectable
3v3nB-5ikgA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oex -

(-)
no annotation 4 GLN A 501
HIS A 528
GLY A 526
GLY A 478
None
CU  A 602 ( 3.0A)
None
None
0.93A 3v3nB-5oexA:
undetectable
3v3nB-5oexA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u3p DH511.4 FAB HEAVY
CHAIN
DH511.4 FAB LIGHT
CHAIN


(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
4 PHE L  98
GLY L  99
GLY H  60
MET H 100
None
0.73A 3v3nB-5u3pL:
undetectable
3v3nB-5u3pL:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u63 THIOREDOXIN
REDUCTASE


(Haemophilus
influenzae)
PF07992
(Pyr_redox_2)
4 GLN A  39
GLY A  42
GLY A 244
ASN A 156
None
FAD  A 401 (-3.3A)
NAP  A 407 (-3.2A)
None
0.91A 3v3nB-5u63A:
9.2
3v3nB-5u63A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vzj EXOSOME COMPLEX
EXONUCLEASE RRP6


(Saccharomyces
cerevisiae)
PF00570
(HRDC)
PF01612
(DNA_pol_A_exo1)
4 HIS J 326
GLY J 322
GLY J 388
ASN J 384
A  M  14 ( 3.9A)
None
None
None
0.94A 3v3nB-5vzjJ:
undetectable
3v3nB-5vzjJ:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xgv PYRE3

(Streptomyces
rugosporus)
no annotation 4 GLN A  56
ARG A 322
GLY A 440
GLY A 289
None
0.73A 3v3nB-5xgvA:
27.0
3v3nB-5xgvA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zqj BETA-XYLOSIDASE

(Bacillus
pumilus)
no annotation 4 ARG A 207
HIS A 210
GLY A 502
ASN A 413
None
0.93A 3v3nB-5zqjA:
undetectable
3v3nB-5zqjA:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b9r HYDROXYETHYLPHOSPHON
ATE DIOXYGENASE


(Streptomyces
albus)
no annotation 4 PHE A 187
HIS A 190
GLY A 148
GLY A 209
None
FE  A 501 ( 3.3A)
None
None
0.73A 3v3nB-6b9rA:
undetectable
3v3nB-6b9rA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b9s METHYLPHOSPHONATE
SYNTHASE


(Nitrosopumilus
maritimus)
no annotation 4 PHE A 187
HIS A 190
GLY A 147
GLY A 210
None
FE  A 501 (-3.6A)
None
None
0.82A 3v3nB-6b9sA:
undetectable
3v3nB-6b9sA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bdz DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 10


(Homo sapiens)
no annotation 4 PHE A 389
GLY A 386
GLY A 264
ASN A 220
None
0.86A 3v3nB-6bdzA:
undetectable
3v3nB-6bdzA:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6btm ALTERNATIVE COMPLEX
III SUBUNIT B


(Flavobacterium
johnsoniae)
no annotation 4 GLN B 281
HIS B 279
GLY B 290
GLY B 259
None
0.80A 3v3nB-6btmB:
undetectable
3v3nB-6btmB:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f4a EXORIBONUCLEASE II,
MITOCHONDRIAL


([Candida]
glabrata)
no annotation 4 PHE A 503
HIS A 781
GLY A 501
GLY A 771
None
0.74A 3v3nB-6f4aA:
undetectable
3v3nB-6f4aA:
12.70