SIMILAR PATTERNS OF AMINO ACIDS FOR 3UT5_B_LOCB502_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d2r | PROTEIN(TRYPTOPHANYL TRNASYNTHETASE) (Geobacillusstearothermophilus) |
PF00579(tRNA-synt_1b) | 5 | LEU A 272ALA A 220MET A 193ILE A 213ILE A 16 | None | 1.13A | 3ut5B-1d2rA:undetectable | 3ut5B-1d2rA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dt2 | EXFOLIATIVE TOXIN B (Staphylococcusaureus) |
PF13365(Trypsin_2) | 5 | LEU A 234LEU A 115ASN A 63ILE A 55ILE A 117 | None | 1.11A | 3ut5B-1dt2A:undetectable | 3ut5B-1dt2A:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1htd | ATROLYSIN C (Crotalus atrox) |
PF01421(Reprolysin) | 5 | LEU A 47LEU A 148ASN A 147MET A 116ILE A 198 | None | 1.11A | 3ut5B-1htdA:undetectable | 3ut5B-1htdA:19.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i8a | ENDO-1,4-BETA-XYLANASE A (Thermotogamaritima) |
PF06452(CBM9_1) | 5 | LEU A 52LEU A 184ASN A 183ILE A 150ILE A 25 | None | 1.08A | 3ut5B-1i8aA:undetectable | 3ut5B-1i8aA:18.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j08 | GLUTAREDOXIN-LIKEPROTEIN (Pyrococcushorikoshii) |
PF00085(Thioredoxin)PF13192(Thioredoxin_3) | 5 | LYS A 215ALA A 156ILE A 171LYS A 158ILE A 138 | None | 1.15A | 3ut5B-1j08A:undetectable | 3ut5B-1j08A:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kh2 | ARGININOSUCCINATESYNTHETASE (Thermusthermophilus) |
PF00764(Arginosuc_synth) | 5 | LEU A 99ALA A 112THR A 51ALA A 53ILE A 29 | None | 1.02A | 3ut5B-1kh2A:undetectable | 3ut5B-1kh2A:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kug | METALLOPROTEINASE (Protobothropsmucrosquamatus) |
PF01421(Reprolysin) | 5 | CYH A 46LEU A 49LEU A 150MET A 118ILE A 53 | None | 1.16A | 3ut5B-1kugA:undetectable | 3ut5B-1kugA:17.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1on9 | METHYLMALONYL-COACARBOXYLTRANSFERASE12S SUBUNIT (Propionibacteriumfreudenreichii) |
PF01039(Carboxyl_trans) | 5 | CYH A 179ALA A 183ASN A 162ALA A 173ILE A 193 | None | 1.17A | 3ut5B-1on9A:2.8 | 3ut5B-1on9A:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wni | TRIMERELYSIN II (Protobothropsflavoviridis) |
PF01421(Reprolysin) | 5 | LEU A 47LEU A 148ASN A 147MET A 116ILE A 197 | None | 1.13A | 3ut5B-1wniA:undetectable | 3ut5B-1wniA:15.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x5n | HARMONIN (Homo sapiens) |
PF00595(PDZ) | 5 | CYH A 31LEU A 29LEU A 85ILE A 45ILE A 65 | None | 1.13A | 3ut5B-1x5nA:undetectable | 3ut5B-1x5nA:15.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xtz | RIBOSE-5-PHOSPHATEISOMERASE (Saccharomycescerevisiae) |
PF06026(Rib_5-P_isom_A) | 5 | LEU A 34ASN A 33THR A 138ILE A 44ILE A 42 | None | 1.17A | 3ut5B-1xtzA:undetectable | 3ut5B-1xtzA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y8p | [PYRUVATEDEHYDROGENASE[LIPOAMIDE]] KINASEISOZYME 3 (Homo sapiens) |
PF02518(HATPase_c)PF10436(BCDHK_Adom3) | 5 | LYS A 250ASN A 251THR A 352ALA A 354ILE A 356 | ATP A 504 (-3.4A)ATP A 504 ( 2.7A)ATP A 504 (-4.1A)NoneNone | 1.18A | 3ut5B-1y8pA:undetectable | 3ut5B-1y8pA:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zuj | HYPOTHETICAL PROTEINLLACC01001955 (Lactococcuslactis) |
no annotation | 5 | ALA A 147LYS A 150LEU A 151LYS A 67ILE A 38 | None | 1.10A | 3ut5B-1zujA:undetectable | 3ut5B-1zujA:18.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bu2 | PYRUVATEDEHYDROGENSAE KINASEISOENZYME 2 (Homo sapiens) |
PF02518(HATPase_c)PF10436(BCDHK_Adom3) | 5 | LYS A 246ASN A 247THR A 346ALA A 348ILE A 350 | ATP A1386 ( 4.1A) MG A1388 ( 2.7A)ATP A1386 (-3.9A)NoneNone | 1.12A | 3ut5B-2bu2A:undetectable | 3ut5B-2bu2A:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2buc | DIPEPTIDYL PEPTIDASEIV (Sus scrofa) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 5 | LEU A 410LEU A 436ASN A 437LYS A 441ILE A 397 | None | 1.06A | 3ut5B-2bucA:2.9 | 3ut5B-2bucA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fur | HYPOTHETICAL PROTEIN (Thermoplasmaacidophilum) |
PF12900(Pyridox_ox_2) | 5 | ALA A 26LEU A 28ASN A 31ALA A 104ILE A 106 | None | 1.03A | 3ut5B-2furA:undetectable | 3ut5B-2furA:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hfh | GENESIS (Rattusnorvegicus) |
PF00250(Forkhead) | 5 | LEU A 55ASN A 58ALA A 15ILE A 33ILE A 29 | None | 1.12A | 3ut5B-2hfhA:undetectable | 3ut5B-2hfhA:14.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2la4 | NUCLEAR ANDCYTOPLASMICPOLYADENYLATEDRNA-BINDING PROTEINPUB1 (Saccharomycescerevisiae) |
PF00076(RRM_1) | 5 | ALA A 395THR A 341ALA A 343ILE A 345ILE A 381 | None | 1.01A | 3ut5B-2la4A:undetectable | 3ut5B-2la4A:11.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o4e | O-GLCNACASE NAGJ (Clostridiumperfringens) |
PF00963(Cohesin) | 5 | LEU A 134LEU A 49ASN A 48ALA A 125ILE A 160 | None | 1.18A | 3ut5B-2o4eA:undetectable | 3ut5B-2o4eA:15.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o7p | RIBOFLAVINBIOSYNTHESIS PROTEINRIBD (Escherichiacoli) |
PF00383(dCMP_cyt_deam_1)PF01872(RibD_C) | 5 | LEU A 288ALA A 189LEU A 191THR A 196ILE A 232 | NoneNoneNoneNAP A 402 (-3.3A)NAP A 402 ( 4.8A) | 1.18A | 3ut5B-2o7pA:undetectable | 3ut5B-2o7pA:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2okq | HYPOTHETICAL PROTEINYBAA (Shigellaflexneri) |
PF07237(DUF1428) | 5 | ALA A 82LYS A 85MET A 92ALA A 26ILE A 38 | None | 0.99A | 3ut5B-2okqA:undetectable | 3ut5B-2okqA:15.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p91 | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE[NADH] (Aquifexaeolicus) |
PF13561(adh_short_C2) | 5 | LEU A 159THR A 27ALA A 36ILE A 237ILE A 39 | None | 1.00A | 3ut5B-2p91A:7.2 | 3ut5B-2p91A:22.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w4g | MYOSIN HEAVY CHAIN,SKELETAL MUSCLE,ADULT (Gallus gallus) |
PF00063(Myosin_head)PF02736(Myosin_N) | 5 | ALA M 197LEU M 218THR M 451ALA M 263ILE M 250 | None | 1.10A | 3ut5B-2w4gM:undetectable | 3ut5B-2w4gM:18.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wcu | PROTEIN FUCU HOMOLOG (Mus musculus) |
PF05025(RbsD_FucU) | 5 | LEU A 11LEU A 19MET A 22ILE A 48ILE A 28 | None | 1.18A | 3ut5B-2wcuA:undetectable | 3ut5B-2wcuA:15.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z2b | DIHYDROOROTASE (Escherichiacoli) |
PF01979(Amidohydro_1) | 5 | CYH A 285LEU A 237LEU A 265LYS A 6ILE A 302 | None | 1.13A | 3ut5B-2z2bA:undetectable | 3ut5B-2z2bA:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zci | PHOSPHOENOLPYRUVATECARBOXYKINASE [GTP] (Corynebacteriumglutamicum) |
PF00821(PEPCK_C)PF17297(PEPCK_N) | 5 | LEU A 252ALA A 269LEU A 416ALA A 414ILE A 412 | None | 0.96A | 3ut5B-2zciA:undetectable | 3ut5B-2zciA:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aag | GENERALGLYCOSYLATIONPATHWAY PROTEIN (Campylobacterjejuni) |
PF02516(STT3) | 5 | LEU A 491ALA A 682LEU A 562LYS A 695ILE A 560 | NoneMLY A 493 ( 3.6A)NoneMLY A 694 ( 3.3A)None | 1.12A | 3ut5B-3aagA:undetectable | 3ut5B-3aagA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b59 | GLYOXALASE/BLEOMYCINRESISTANCEPROTEIN/DIOXYGENASE (Novosphingobiumaromaticivorans) |
PF00903(Glyoxalase) | 5 | ALA A 188LEU A 147ASN A 197ILE A 9ILE A 68 | None | 1.01A | 3ut5B-3b59A:undetectable | 3ut5B-3b59A:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmv | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 5 | ALA A1174LYS A1177LEU A1178ASN A1181ILE A1141 | None | 1.00A | 3ut5B-3cmvA:undetectable | 3ut5B-3cmvA:16.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmv | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 5 | LEU A 178ALA A 131THR A 89ALA A 91ILE A 93 | None | 1.14A | 3ut5B-3cmvA:undetectable | 3ut5B-3cmvA:16.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmv | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 5 | LYS A1177LEU A1178ASN A1181ILE A1128ILE A1141 | None | 1.06A | 3ut5B-3cmvA:undetectable | 3ut5B-3cmvA:16.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ewm | UNCHARACTERIZEDSUGAR KINASE PH1459 (Pyrococcushorikoshii) |
PF00294(PfkB) | 5 | ALA A 5LEU A 254MET A 250ILE A 157ILE A 188 | None | 1.11A | 3ut5B-3ewmA:6.1 | 3ut5B-3ewmA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fn4 | NAD-DEPENDENTFORMATEDEHYDROGENASE (Moraxella sp.) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | ALA A 131LEU A 103THR A 119ALA A 117ILE A 93 | None | 1.15A | 3ut5B-3fn4A:undetectable | 3ut5B-3fn4A:23.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gr8 | NADPH DEHYDROGENASE (Geobacilluskaustophilus) |
PF00724(Oxidored_FMN) | 5 | ALA A 97LYS A 17LEU A 16ASN A 18ILE A 57 | None | 1.18A | 3ut5B-3gr8A:undetectable | 3ut5B-3gr8A:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h1g | CHEMOTAXIS PROTEINCHEY HOMOLOG (Helicobacterpylori) |
PF00072(Response_reg) | 5 | LEU A 64LYS A 40LEU A 41ASN A 44ILE A 77 | None | 1.02A | 3ut5B-3h1gA:5.5 | 3ut5B-3h1gA:14.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ilr | HEPARIN LYASE I (Bacteroidesthetaiotaomicron) |
PF14099(Polysacc_lyase) | 5 | LEU A 317THR A 277ALA A 279ILE A 334ILE A 240 | None | 1.12A | 3ut5B-3ilrA:undetectable | 3ut5B-3ilrA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iuk | UNCHARACTERIZEDPROTEIN (Paenarthrobacteraurescens) |
PF05960(DUF885) | 5 | ALA A 111LEU A 104ASN A 105ILE A 169ILE A 165 | None | 1.03A | 3ut5B-3iukA:undetectable | 3ut5B-3iukA:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jxf | RECEPTOR-TYPETYROSINE-PROTEINPHOSPHATASE ZETA (Homo sapiens) |
PF00194(Carb_anhydrase) | 5 | LEU A 217ASN A 108ALA A 123LYS A 122ILE A 155 | None | 1.12A | 3ut5B-3jxfA:undetectable | 3ut5B-3jxfA:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3knw | PUTATIVETRANSCRIPTIONALREGULATOR (TETR/ACRRFAMILY) (Acinetobactersp. ADP1) |
PF00440(TetR_N)PF16925(TetR_C_13) | 5 | ALA A 84LYS A 87LEU A 88ALA A 163ILE A 166 | None | 1.17A | 3ut5B-3knwA:undetectable | 3ut5B-3knwA:17.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lxr | IPGB2 (Shigellaflexneri) |
PF03278(IpaB_EvcA) | 5 | LYS F 172LEU F 173ASN F 176MET F 177ILE F 108 | None | 0.97A | 3ut5B-3lxrF:undetectable | 3ut5B-3lxrF:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m3p | GLUTAMINE AMIDOTRANSFERASE (Methylobacillusflagellatus) |
PF00117(GATase) | 5 | ALA A 229LEU A 128ALA A 163ILE A 171ILE A 153 | None | 1.13A | 3ut5B-3m3pA:undetectable | 3ut5B-3m3pA:18.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mb8 | PURINE NUCLEOSIDEPHOSPHORYLASE (Toxoplasmagondii) |
PF01048(PNP_UDP_1) | 5 | CYH A 243LEU A 246LEU A 143ALA A 94ILE A 25 | None | 1.10A | 3ut5B-3mb8A:undetectable | 3ut5B-3mb8A:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3myr | NICKEL-DEPENDENTHYDROGENASE LARGESUBUNIT (Allochromatiumvinosum) |
PF00374(NiFeSe_Hases) | 5 | LEU B1536ALA B1021ILE B1019LYS B1003ILE B1028 | None | 1.18A | 3ut5B-3myrB:undetectable | 3ut5B-3myrB:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oc4 | OXIDOREDUCTASE,PYRIDINENUCLEOTIDE-DISULFIDEFAMILY (Enterococcusfaecalis) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | LEU A -1LEU A 309ASN A 307ALA A 15ILE A 106 | None | 1.14A | 3ut5B-3oc4A:undetectable | 3ut5B-3oc4A:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3out | GLUTAMATE RACEMASE (Francisellatularensis) |
PF01177(Asp_Glu_race) | 5 | LEU A 216ASN A 219ALA A 69ILE A 71ILE A 7 | None | 1.01A | 3ut5B-3outA:undetectable | 3ut5B-3outA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p09 | BETA-LACTAMASE (Francisellatularensis) |
PF13354(Beta-lactamase2) | 5 | ALA A 118ALA A 103ILE A 88LYS A 104ILE A 93 | None | 1.03A | 3ut5B-3p09A:undetectable | 3ut5B-3p09A:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pbk | FATTY ACYL-ADENYLATELIGASE (Escherichiacoli) |
PF00501(AMP-binding) | 5 | LYS A 119LEU A 120ALA A 78ILE A 80ILE A 132 | None | 0.91A | 3ut5B-3pbkA:2.1 | 3ut5B-3pbkA:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pr2 | TRYPTOPHAN SYNTHASEBETA CHAIN (Salmonellaenterica) |
PF00291(PALP) | 5 | LEU B 271ALA B 284THR B 199ALA B 191ILE B 238 | None | 1.09A | 3ut5B-3pr2B:undetectable | 3ut5B-3pr2B:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r3s | OXIDOREDUCTASE (Salmonellaenterica) |
PF13561(adh_short_C2) | 5 | ALA A 68THR A 184ALA A 133ILE A 131ILE A 182 | NoneNAD A 300 ( 4.4A)NoneNoneNone | 1.18A | 3ut5B-3r3sA:6.8 | 3ut5B-3r3sA:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rr5 | DNA LIGASE (Thermococcussp. 1519) |
PF01068(DNA_ligase_A_M)PF04675(DNA_ligase_A_N)PF04679(DNA_ligase_A_C) | 5 | LEU A 300LYS A 383LEU A 349ASN A 348ILE A 277 | None | 1.16A | 3ut5B-3rr5A:undetectable | 3ut5B-3rr5A:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sz3 | TRYPTOPHANYL-TRNASYNTHETASE (Vibrio cholerae) |
PF00579(tRNA-synt_1b) | 5 | ALA A 226ASN A 208MET A 199ILE A 219ILE A 18 | None | 1.05A | 3ut5B-3sz3A:undetectable | 3ut5B-3sz3A:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tx1 | UDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINEREDUCTASE (Listeriamonocytogenes) |
PF01565(FAD_binding_4)PF02873(MurB_C) | 5 | ALA A 99LEU A 101ALA A 105ILE A 93LYS A 106 | None | 1.17A | 3ut5B-3tx1A:undetectable | 3ut5B-3tx1A:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v2h | D-BETA-HYDROXYBUTYRATE DEHYDROGENASE (Sinorhizobiummeliloti) |
PF13561(adh_short_C2) | 5 | LEU A 22MET A 0ALA A 237ILE A 136ILE A 84 | None | 1.06A | 3ut5B-3v2hA:7.3 | 3ut5B-3v2hA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v8v | RIBOSOMAL RNA LARGESUBUNITMETHYLTRANSFERASE L (Escherichiacoli) |
PF01170(UPF0020)PF02926(THUMP)PF10672(Methyltrans_SAM) | 5 | LEU A 43LEU A 20THR A 8ALA A 6ILE A 57 | None | 1.15A | 3ut5B-3v8vA:3.7 | 3ut5B-3v8vA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vcy | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Aliivibriofischeri) |
PF00275(EPSP_synthase) | 5 | ALA A 174LEU A 183MET A 159ALA A 166ILE A 168 | NoneNoneNoneUD1 A 501 ( 4.7A)None | 1.11A | 3ut5B-3vcyA:undetectable | 3ut5B-3vcyA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wtc | PUTATIVEOXIDOREDUCTASE (Gluconobacteroxydans) |
PF00106(adh_short) | 5 | LEU A 73THR A 11ALA A 9ILE A 7ILE A 33 | None | 1.00A | 3ut5B-3wtcA:6.8 | 3ut5B-3wtcA:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4awn | DEOXYRIBONUCLEASE-1 (Homo sapiens) |
PF03372(Exo_endo_phos) | 5 | ALA A 47LYS A 50LEU A 51ASN A 54ILE A 8 | None | 1.14A | 3ut5B-4awnA:undetectable | 3ut5B-4awnA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bwr | PROTEINCORRESPONDING TOLOCUS C5321 FROMCFT073 E.COLI STRAIN (Escherichiacoli) |
PF08238(Sel1) | 5 | LEU A 84ALA A 82LEU A 94ASN A 93ILE A 77 | None | 1.17A | 3ut5B-4bwrA:undetectable | 3ut5B-4bwrA:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4erd | TELOMERASEASSOCIATED PROTEINP65 (Tetrahymenathermophila) |
PF08777(RRM_3) | 5 | LYS A 486LEU A 487THR A 501ILE A 383ILE A 381 | None | 1.18A | 3ut5B-4erdA:undetectable | 3ut5B-4erdA:14.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h41 | PUTATIVEALPHA-L-FUCOSIDASE (Bacteroidesthetaiotaomicron) |
PF14488(DUF4434)PF17134(DUF5109) | 5 | LEU A 355LYS A 318LEU A 319THR A 298ILE A 60 | None | 1.15A | 3ut5B-4h41A:3.6 | 3ut5B-4h41A:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i2w | PROTEIN UNC-45 (Caenorhabditiselegans) |
PF11701(UNC45-central) | 5 | LEU A 753LEU A 799THR A 812ILE A 770ILE A 776 | None | 1.09A | 3ut5B-4i2wA:undetectable | 3ut5B-4i2wA:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j4m | ZINC-DEPENDENTMETALLOPROTEINASE (Protobothropsmucrosquamatus) |
PF01421(Reprolysin) | 5 | LEU A 49LEU A 150ASN A 149MET A 118ILE A 199 | None | 1.16A | 3ut5B-4j4mA:undetectable | 3ut5B-4j4mA:16.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jej | GERANYLGERANYLGLYCERYL PHOSPHATESYNTHASE (Flavobacteriumjohnsoniae) |
PF01884(PcrB) | 5 | ALA A 96LEU A 98ILE A 13LYS A 175ILE A 206 | None | 1.13A | 3ut5B-4jejA:undetectable | 3ut5B-4jejA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jx8 | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE[NADH] FABI (Escherichiacoli) |
PF13561(adh_short_C2) | 5 | LEU A 144THR A 12ALA A 21ILE A 222ILE A 24 | NAD A 302 (-3.9A)NoneNoneNoneNone | 0.95A | 3ut5B-4jx8A:6.7 | 3ut5B-4jx8A:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o1n | SUPERANTIGEN-LIKEPROTEIN (Staphylococcusaureus) |
PF02876(Stap_Strp_tox_C)PF09199(SSL_OB) | 5 | LEU A 142ASN A 195MET A 166ILE A 133ILE A 189 | None | 1.12A | 3ut5B-4o1nA:undetectable | 3ut5B-4o1nA:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p1e | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT (Escherichiafergusonii) |
PF03480(DctP) | 5 | LEU A 248LEU A 30ASN A 31ILE A 242ILE A 241 | None | 1.13A | 3ut5B-4p1eA:undetectable | 3ut5B-4p1eA:19.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r7z | CELL DIVISIONCONTROL PROTEIN 21 (Pyrococcusfuriosus) |
PF00493(MCM) | 5 | LEU A 325ALA A 801LEU A 761MET A 764ILE A 772 | None | 1.13A | 3ut5B-4r7zA:undetectable | 3ut5B-4r7zA:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s1w | GLUTAMINE--FRUCTOSE-6-PHOSPHATEAMINOTRANSFERASE[ISOMERIZING] (Staphylococcusaureus) |
PF01380(SIS) | 5 | LYS A 435THR A 404ALA A 408ILE A 412ILE A 267 | None | 1.09A | 3ut5B-4s1wA:5.5 | 3ut5B-4s1wA:22.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u08 | LIC11098 (Leptospirainterrogans) |
PF00560(LRR_1)PF13855(LRR_8) | 5 | LEU A 84LEU A 56ASN A 55ILE A 68ILE A 41 | None | 1.14A | 3ut5B-4u08A:undetectable | 3ut5B-4u08A:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u3t | PENICILLIN-BINDINGPROTEIN 2 (Neisseriagonorrhoeae) |
PF00905(Transpeptidase) | 5 | LEU A 431THR A 534ALA A 532ILE A 530ILE A 519 | None | 0.87A | 3ut5B-4u3tA:undetectable | 3ut5B-4u3tA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xz3 | ACYL-COA SYNTHETASE(NDP FORMING) (CandidatusKorarchaeumcryptofilum) |
PF13380(CoA_binding_2)PF13607(Succ_CoA_lig) | 5 | ALA A 451LEU A 447MET A 444THR A 378ALA A 376 | None | 1.10A | 3ut5B-4xz3A:undetectable | 3ut5B-4xz3A:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zng | PROLIDASE (Lactococcuslactis) |
no annotation | 5 | LEU C 133ASN C 312ALA C 270ILE C 316ILE C 308 | None | 1.15A | 3ut5B-4zngC:undetectable | 3ut5B-4zngC:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ao0 | DEOXYNUCLEOSIDETRIPHOSPHATETRIPHOSPHOHYDROLASESAMHD1 (Homo sapiens) |
PF01966(HD) | 5 | CYH A 205LEU A 204ALA A 202MET A 254ILE A 250 | None | 1.18A | 3ut5B-5ao0A:undetectable | 3ut5B-5ao0A:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c2z | EXFOLIATIVE TOXIN D2 (Staphylococcusaureus) |
PF00089(Trypsin) | 5 | LEU A 266LEU A 146ASN A 94ILE A 86ILE A 148 | None | 1.06A | 3ut5B-5c2zA:undetectable | 3ut5B-5c2zA:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cay | ENVELOPEGLYCOPROTEIN GP120CORE FROM ST STRAINOF HIV-2 (Humanimmunodeficiencyvirus 2) |
PF00516(GP120) | 6 | ALA G 282LYS G 303LEU G 301ASN G 302ILE G 298ILE G 466 | NoneNoneNoneNAG G 610 (-3.3A)NoneNone | 1.44A | 3ut5B-5cayG:undetectable | 3ut5B-5cayG:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f5o | NUCLEOPROTEIN (Marburgmarburgvirus) |
PF05505(Ebola_NP) | 5 | CYH A 136LEU A 133LEU A 56ILE A 182ILE A 42 | None | 0.93A | 3ut5B-5f5oA:undetectable | 3ut5B-5f5oA:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fir | 5'-3'EXORIBONUCLEASE 2HOMOLOG (Caenorhabditiselegans) |
PF03159(XRN_N) | 5 | LEU A 196ALA A 101ASN A 56ILE A 85ILE A 81 | NoneNoneSO4 A1788 (-4.7A)NoneNone | 1.17A | 3ut5B-5firA:undetectable | 3ut5B-5firA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fno | MANGANESELIPOXYGENASE (Magnaportheoryzae) |
PF00305(Lipoxygenase) | 5 | LEU A 594LEU A 538MET A 541ALA A 462ILE A 402 | None | 1.14A | 3ut5B-5fnoA:undetectable | 3ut5B-5fnoA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gri | ISOCITRATEDEHYDROGENASE [NAD]SUBUNIT ALPHA,MITOCHONDRIAL (Homo sapiens) |
PF00180(Iso_dh) | 5 | LEU A 93LYS A 65ASN A 64ILE A 53ILE A 10 | None | 1.17A | 3ut5B-5griA:undetectable | 3ut5B-5griA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h64 | SERINE/THREONINE-PROTEIN KINASE MTOR (Homo sapiens) |
PF00454(PI3_PI4_kinase)PF02259(FAT)PF02260(FATC)PF08771(FRB_dom)PF11865(DUF3385) | 5 | ALA A1990LEU A1995ASN A1997MET A1998ILE A1943 | None | 1.12A | 3ut5B-5h64A:undetectable | 3ut5B-5h64A:10.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i2g | DIOL DEHYDRATASE (Roseburiainulinivorans) |
PF01228(Gly_radical)PF02901(PFL-like) | 5 | CYH A 529LEU A 530LEU A 179ASN A 180ILE A 210 | None | 1.16A | 3ut5B-5i2gA:2.0 | 3ut5B-5i2gA:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ik2 | ATP SYNTHASE GAMMACHAIN (Caldalkalibacillusthermarum) |
PF00231(ATP-synt) | 5 | LEU G 189MET G 67ALA G 222ILE G 226ILE G 157 | None | 1.12A | 3ut5B-5ik2G:undetectable | 3ut5B-5ik2G:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iy9 | DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB1 (Homo sapiens) |
PF00623(RNA_pol_Rpb1_2)PF04983(RNA_pol_Rpb1_3)PF04990(RNA_pol_Rpb1_7)PF04992(RNA_pol_Rpb1_6)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4) | 5 | LEU A1216LEU A1166MET A1296ILE A1259ILE A1235 | None | 1.13A | 3ut5B-5iy9A:undetectable | 3ut5B-5iy9A:11.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jqe | SUGAR ABCTRANSPORTERSUBSTRATE-BINDINGPROTEIN,CASPASE-8CHIMERA (Escherichiacoli) |
PF01335(DED)PF13416(SBP_bac_8) | 5 | LEU A 151LEU A 134THR A 257ILE A 144LYS A 139 | None | 1.11A | 3ut5B-5jqeA:undetectable | 3ut5B-5jqeA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kd5 | METALLOPEPTIDASE (Bacteroidesthetaiotaomicron) |
PF13402(Peptidase_M60)PF17291(M60-like_N) | 5 | LYS A 844LEU A 845ALA A 794ILE A 792ILE A 803 | None | 1.08A | 3ut5B-5kd5A:undetectable | 3ut5B-5kd5A:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5koh | NITROGENASE FEMOBETA SUBUNIT PROTEINNIFK (Gluconacetobacterdiazotrophicus) |
PF00148(Oxidored_nitro)PF11844(DUF3364) | 5 | LEU B 457LYS B 488LEU B 485ILE B 364ILE B 378 | None | 1.15A | 3ut5B-5kohB:undetectable | 3ut5B-5kohB:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ks1 | 1-DEOXY-D-XYLULOSE5-PHOSPHATEREDUCTOISOMERASE (Vibriovulnificus) |
PF02670(DXP_reductoisom)PF08436(DXP_redisom_C)PF13288(DXPR_C) | 5 | LEU A 318LYS A 247LEU A 183ALA A 235ILE A 233 | None | 1.11A | 3ut5B-5ks1A:3.9 | 3ut5B-5ks1A:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kzm | TRYPTOPHAN SYNTHASEBETA CHAIN (Francisellatularensis) |
PF00291(PALP) | 5 | LEU B 270ALA B 283THR B 198ALA B 190ILE B 237 | None | 1.16A | 3ut5B-5kzmB:undetectable | 3ut5B-5kzmB:20.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5mjs | TUBULIN BETA CHAIN (Schizosaccharomycespombe) |
no annotation | 5 | LEU A 253MET A 257THR A 311ALA A 313ILE A 367 | None | 1.09A | 3ut5B-5mjsA:53.6 | 3ut5B-5mjsA:58.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5n5n | TUBULIN BETA CHAIN (Homo sapiens) |
no annotation | 6 | ALA B 250LYS B 254ASN B 258MET B 259THR B 314ILE B 378 | None | 0.84A | 3ut5B-5n5nB:54.4 | 3ut5B-5n5nB:96.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5n5n | TUBULIN BETA CHAIN (Homo sapiens) |
no annotation | 5 | LEU B 255ASN B 258MET B 259THR B 314ILE B 378 | None | 0.92A | 3ut5B-5n5nB:54.4 | 3ut5B-5n5nB:96.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5n5n | TUBULIN BETA CHAIN (Homo sapiens) |
no annotation | 5 | LEU B 255MET B 259THR B 314ALA B 316ILE B 378 | None | 1.02A | 3ut5B-5n5nB:54.4 | 3ut5B-5n5nB:96.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t0v | IRON SULFUR CLUSTERASSEMBLY PROTEIN 1,MITOCHONDRIAL (Saccharomycescerevisiae) |
PF01491(Frataxin_Cyay) | 5 | ALA a 150LEU a 75MET a 73ALA a 143ILE a 121 | None | 1.08A | 3ut5B-5t0va:undetectable | 3ut5B-5t0va:14.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tc1 | MATURATION PROTEIN (Escherichiavirus MS2) |
PF03863(Phage_mat-A) | 5 | CYH M 101ALA M 98LEU M 96ALA M 349ILE M 333 | None | 1.13A | 3ut5B-5tc1M:undetectable | 3ut5B-5tc1M:24.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wuq | ECF RNA POLYMERASESIGMA FACTOR SIGW (Bacillussubtilis) |
PF04542(Sigma70_r2)PF08281(Sigma70_r4_2) | 5 | ALA A 179LYS A 182LEU A 184ILE A 134ILE A 130 | None | 1.13A | 3ut5B-5wuqA:undetectable | 3ut5B-5wuqA:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xsq | NUCLEOPROTEIN (Marburgmarburgvirus) |
PF05505(Ebola_NP) | 5 | CYH A 120LEU A 117LEU A 40ILE A 166ILE A 26 | None | 0.93A | 3ut5B-5xsqA:undetectable | 3ut5B-5xsqA:23.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyi | UNCHARACTERIZEDPROTEIN (Trichomonasvaginalis) |
PF00333(Ribosomal_S5)PF03719(Ribosomal_S5_C) | 5 | ALA C 198LEU C 202MET C 205ALA C 118ILE C 116 | U 2 4 ( 4.3A)NoneNoneNoneNone | 1.13A | 3ut5B-5xyiC:undetectable | 3ut5B-5xyiC:19.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6apx | MALTOSE-BINDINGPERIPLASMICPROTEIN,DUALSPECIFICITY PROTEINPHOSPHATASE 1 (Escherichiacoli;Homo sapiens) |
no annotation | 5 | LEU A 139LEU A 122ASN A 124ILE A 132LYS A 127 | None | 1.12A | 3ut5B-6apxA:undetectable | 3ut5B-6apxA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c9m | N-ALPHA-ACETYLTRANSFERASE 10N-ALPHA-ACETYLTRANSFERASE 15, NATAAUXILIARY SUBUNIT (Homo sapiens) |
no annotation | 5 | LEU A 541LEU B 11ASN B 13MET B 14ALA B 6 | None | 0.93A | 3ut5B-6c9mA:undetectable | 3ut5B-6c9mA:9.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d6v | TELOMERASEASSOCIATED PROTEINP65 (Tetrahymenathermophila) |
no annotation | 5 | LYS H 486LEU H 487THR H 501ILE H 383ILE H 381 | None | 1.18A | 3ut5B-6d6vH:undetectable | 3ut5B-6d6vH:12.39 |