SIMILAR PATTERNS OF AMINO ACIDS FOR 3UQ6_B_ADNB401_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aj8 | CITRATE SYNTHASE (Pyrococcusfuriosus) |
PF00285(Citrate_synt) | 4 | LEU A 77GLY A 76MET A 164ASN A 160 | None | 1.18A | 3uq6B-1aj8A:undetectable | 3uq6B-1aj8A:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aog | TRYPANOTHIONEREDUCTASE (Trypanosomacruzi) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | LEU A 18GLY A 14PHE A 123ASN A 55 | NoneFAD A 492 (-3.3A)NoneNone | 1.06A | 3uq6B-1aogA:5.1 | 3uq6B-1aogA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bkd | SON OF SEVENLESS-1 (Homo sapiens) |
PF00617(RasGEF)PF00618(RasGEF_N) | 4 | LEU S 934GLY S 931MET S 824ASN S 869 | None | 1.11A | 3uq6B-1bkdS:undetectable | 3uq6B-1bkdS:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bp1 | BACTERICIDAL/PERMEABILITY-INCREASINGPROTEIN (Homo sapiens) |
PF01273(LBP_BPI_CETP)PF02886(LBP_BPI_CETP_C) | 4 | LEU A 154GLY A 152MET A 100PHE A 41 | None | 1.12A | 3uq6B-1bp1A:undetectable | 3uq6B-1bp1A:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1br2 | MYOSIN (Gallus gallus) |
PF00063(Myosin_head)PF02736(Myosin_N) | 4 | LEU A 307GLY A 309PHE A 290ASN A 364 | None | 1.32A | 3uq6B-1br2A:undetectable | 3uq6B-1br2A:18.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fs0 | ATP SYNTHASE GAMMASUBUNIT (Escherichiacoli) |
PF00231(ATP-synt) | 4 | LEU G 115GLY G 131PHE G 96ASN G 127 | None | 1.24A | 3uq6B-1fs0G:undetectable | 3uq6B-1fs0G:18.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j9m | DD-TRANSPEPTIDASE (Streptomycessp. K15) |
PF00768(Peptidase_S11) | 4 | LEU A 92GLY A 91PHE A 170ASN A 198 | None | 1.11A | 3uq6B-1j9mA:undetectable | 3uq6B-1j9mA:22.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q18 | GLUCOKINASE (Escherichiacoli) |
PF02685(Glucokinase) | 4 | LEU A 298GLY A 262MET A 241PHE A 268 | None | 1.23A | 3uq6B-1q18A:undetectable | 3uq6B-1q18A:25.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qdl | PROTEIN(ANTHRANILATESYNTHASE(TRPE-SUBUNIT)) (Sulfolobussolfataricus) |
PF00425(Chorismate_bind)PF04715(Anth_synt_I_N) | 4 | LEU A 281GLY A 313PHE A 228ASN A 233 | None | 1.27A | 3uq6B-1qdlA:undetectable | 3uq6B-1qdlA:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qon | ACETYLCHOLINESTERASE (Drosophilamelanogaster) |
PF00135(COesterase) | 4 | LEU A 510GLY A 489PHE A 235ASN A 163 | NoneNoneNoneNAG A 991 ( 4.6A) | 1.26A | 3uq6B-1qonA:undetectable | 3uq6B-1qonA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r82 | GLYCOPROTEIN-FUCOSYLGALACTOSIDEALPHA-GALACTOSYLTRANSFERASE (Homo sapiens) |
PF03414(Glyco_transf_6) | 4 | LEU A 118GLY A 117MET A 142PHE A 269 | None | 1.17A | 3uq6B-1r82A:undetectable | 3uq6B-1r82A:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tl2 | PROTEIN(TACHYLECTIN-2) (Tachypleustridentatus) |
PF14517(Tachylectin) | 4 | LEU A 109GLY A 130PHE A 137ASN A 168 | NoneNDG A 239 (-3.0A)NoneNDG A 239 (-3.5A) | 1.27A | 3uq6B-1tl2A:undetectable | 3uq6B-1tl2A:17.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1typ | TRYPANOTHIONEREDUCTASE (Crithidiafasciculata) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | LEU A 17GLY A 13PHE A 122ASN A 54 | SPD A 496 (-4.6A)FAD A 493 (-3.2A)NoneNone | 1.08A | 3uq6B-1typA:5.2 | 3uq6B-1typA:22.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u6z | EXOPOLYPHOSPHATASE (Escherichiacoli) |
PF02541(Ppx-GppA) | 4 | LEU A 441GLY A 442PHE A 471ASN A 447 | NoneNoneNoneSO4 A 705 ( 3.9A) | 1.32A | 3uq6B-1u6zA:undetectable | 3uq6B-1u6zA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1umg | 385AA LONG CONSERVEDHYPOTHETICAL PROTEIN (Sulfurisphaeratokodaii) |
PF01950(FBPase_3) | 4 | LEU A 248GLY A 249PHE A 311ASN A 152 | None | 1.22A | 3uq6B-1umgA:undetectable | 3uq6B-1umgA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w8j | MYOSIN VA (Gallus gallus) |
PF00063(Myosin_head) | 4 | LEU A 279GLY A 280PHE A 262ASN A 337 | None | 1.17A | 3uq6B-1w8jA:undetectable | 3uq6B-1w8jA:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xdv | SON OF SEVENLESSPROTEIN HOMOLOG 1 (Homo sapiens) |
PF00169(PH)PF00617(RasGEF)PF00618(RasGEF_N)PF00621(RhoGEF) | 4 | LEU A 934GLY A 931MET A 824ASN A 869 | None | 1.11A | 3uq6B-1xdvA:undetectable | 3uq6B-1xdvA:18.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xt8 | PUTATIVE AMINO-ACIDTRANSPORTERPERIPLASMICSOLUTE-BINDINGPROTEIN (Campylobacterjejuni) |
PF00497(SBP_bac_3) | 4 | GLY A 44MET A 107PHE A 244ASN A 89 | None | 0.90A | 3uq6B-1xt8A:undetectable | 3uq6B-1xt8A:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b0t | NADP ISOCITRATEDEHYDROGENASE (Corynebacteriumglutamicum) |
PF03971(IDH) | 4 | LEU A 567GLY A 570PHE A 574ASN A 617 | None | 1.10A | 3uq6B-2b0tA:undetectable | 3uq6B-2b0tA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bjs | ISOPENICILLIN NSYNTHETASE (Aspergillusnidulans) |
PF03171(2OG-FeII_Oxy)PF14226(DIOX_N) | 4 | LEU A 157GLY A 159MET A 257PHE A 170 | None | 1.33A | 3uq6B-2bjsA:undetectable | 3uq6B-2bjsA:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cl2 | PUTATIVELAMINARINASE (Phanerochaetechrysosporium) |
no annotation | 4 | LEU A 52GLY A 11PHE A 18ASN A 8 | None | 1.14A | 3uq6B-2cl2A:undetectable | 3uq6B-2cl2A:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d5r | CCR4-NOTTRANSCRIPTIONCOMPLEX SUBUNIT 7 (Homo sapiens) |
PF04857(CAF1) | 4 | LEU A 259GLY A 159MET A 39PHE A 189 | None | 1.22A | 3uq6B-2d5rA:undetectable | 3uq6B-2d5rA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f6h | MYOSIN-2 (Saccharomycescerevisiae) |
PF01843(DIL) | 4 | LEU X 299GLY X 302PHE X 232ASN X 258 | None | 1.06A | 3uq6B-2f6hX:undetectable | 3uq6B-2f6hX:18.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hsd | 3-ALPHA, 20BETA-HYDROXYSTEROIDDEHYDROGENASE (Streptomycesexfoliatus) |
PF13561(adh_short_C2) | 4 | LEU A 165GLY A 161MET A 119ASN A 136 | None | 1.27A | 3uq6B-2hsdA:6.1 | 3uq6B-2hsdA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jgr | YEGS (Escherichiacoli) |
PF00781(DAGK_cat) | 4 | LEU A 223GLY A 251PHE A 226ASN A 213 | None | 1.02A | 3uq6B-2jgrA:undetectable | 3uq6B-2jgrA:24.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kr0 | PROTEASOMALUBIQUITIN RECEPTORADRM1 (Homo sapiens) |
PF04683(Proteasom_Rpn13)PF16550(RPN13_C) | 4 | LEU A 288GLY A 341MET A 297PHE A 377 | None | 1.25A | 3uq6B-2kr0A:undetectable | 3uq6B-2kr0A:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mwh | ANTI-HIV LECTIN OAA (Planktothrixagardhii) |
no annotation | 4 | LEU A 114GLY A 130MET A 118ASN A 8 | None | 0.89A | 3uq6B-2mwhA:undetectable | 3uq6B-2mwhA:13.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qzj | TWO-COMPONENTRESPONSE REGULATOR (Clostridioidesdifficile) |
PF00072(Response_reg) | 4 | LEU A 58GLY A 12MET A 81ASN A 16 | None | 1.33A | 3uq6B-2qzjA:undetectable | 3uq6B-2qzjA:16.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2re3 | UNCHARACTERIZEDPROTEIN (Ruegeriapomeroyi) |
PF06938(DUF1285) | 4 | LEU A 175GLY A 166MET A 185PHE A 159 | None | 1.09A | 3uq6B-2re3A:undetectable | 3uq6B-2re3A:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uvf | EXOPOLYGALACTURONASE (Yersiniaenterocolitica) |
PF00295(Glyco_hydro_28)PF12708(Pectate_lyase_3) | 4 | LEU A 333GLY A 356PHE A 347ASN A 359 | None | 1.05A | 3uq6B-2uvfA:undetectable | 3uq6B-2uvfA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uz0 | TRIBUTYRIN ESTERASE (Streptococcuspneumoniae) |
PF00756(Esterase) | 4 | GLY A 159MET A 121PHE A 168ASN A 76 | None | 1.20A | 3uq6B-2uz0A:undetectable | 3uq6B-2uz0A:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wp9 | SUCCINATEDEHYDROGENASEIRON-SULFUR SUBUNIT (Escherichiacoli) |
PF13085(Fer2_3)PF13534(Fer4_17) | 4 | LEU B 97GLY B 96PHE B 110ASN B 71 | None | 1.22A | 3uq6B-2wp9B:undetectable | 3uq6B-2wp9B:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yn9 | POTASSIUM-TRANSPORTING ATPASE ALPHACHAIN 1 (Sus scrofa) |
PF00122(E1-E2_ATPase)PF00689(Cation_ATPase_C)PF00690(Cation_ATPase_N)PF09040(H-K_ATPase_N)PF13246(Cation_ATPase) | 4 | LEU A 567GLY A 591MET A 516PHE A 587 | None | 1.09A | 3uq6B-2yn9A:undetectable | 3uq6B-2yn9A:16.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zzw | ABC TRANSPORTER,SOLUTE-BINDINGPROTEIN (Thermusthermophilus) |
PF03480(DctP) | 4 | GLY A 48MET A 252PHE A 217ASN A 96 | NoneNoneLAC A 401 ( 4.6A)None | 1.30A | 3uq6B-2zzwA:undetectable | 3uq6B-2zzwA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e61 | PUTATIVETRANSCRIPTIONALREPRESSOR OF RIBOSEOPERON (Staphylococcussaprophyticus) |
PF13377(Peripla_BP_3) | 4 | LEU A 64GLY A 95PHE A 74ASN A 125 | NoneNoneGOL A 1 ( 4.5A)None | 1.33A | 3uq6B-3e61A:undetectable | 3uq6B-3e61A:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ewm | UNCHARACTERIZEDSUGAR KINASE PH1459 (Pyrococcushorikoshii) |
PF00294(PfkB) | 4 | LEU A 11GLY A 34PHE A 110ASN A 162 | None | 1.23A | 3uq6B-3ewmA:30.3 | 3uq6B-3ewmA:23.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hoa | THERMOSTABLECARBOXYPEPTIDASE 1 (Thermusthermophilus) |
PF02074(Peptidase_M32) | 4 | LEU A 275GLY A 273PHE A 223ASN A 268 | None | 1.25A | 3uq6B-3hoaA:undetectable | 3uq6B-3hoaA:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ibg | ATPASE, SUBUNIT OFTHE GET COMPLEX (Aspergillusfumigatus) |
PF02374(ArsA_ATPase) | 4 | LEU A 259GLY A 263PHE A 30ASN A 227 | None | 1.25A | 3uq6B-3ibgA:undetectable | 3uq6B-3ibgA:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j04 | MYOSIN-11 (Gallus gallus) |
PF00063(Myosin_head)PF00612(IQ)PF01576(Myosin_tail_1)PF02736(Myosin_N) | 4 | LEU A 307GLY A 309PHE A 290ASN A 364 | None | 1.29A | 3uq6B-3j04A:undetectable | 3uq6B-3j04A:17.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jaf | GLYCINE RECEPTORSUBUNIT ALPHAZ1 (Danio rerio) |
PF02931(Neur_chan_LBD)PF02932(Neur_chan_memb) | 4 | LEU A 200GLY A 65PHE A 230ASN A 77 | None | 1.11A | 3uq6B-3jafA:undetectable | 3uq6B-3jafA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jbl | NLR FAMILY CARDDOMAIN-CONTAININGPROTEIN 4 (Mus musculus) |
no annotation | 4 | LEU K 293GLY K 291MET K 274ASN K 268 | None | 1.33A | 3uq6B-3jblK:undetectable | 3uq6B-3jblK:17.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jbz | SERINE/THREONINE-PROTEIN KINASE MTOR (Homo sapiens) |
PF00454(PI3_PI4_kinase)PF02259(FAT)PF02260(FATC)PF08771(FRB_dom) | 4 | LEU A2201GLY A2203MET A2327PHE A2358 | None | 1.24A | 3uq6B-3jbzA:undetectable | 3uq6B-3jbzA:15.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l6i | UNCHARACTERIZEDLIPOPROTEIN YCEB (Escherichiacoli) |
PF07273(DUF1439) | 4 | LEU A 88GLY A 69MET A 108PHE A 34 | None | 1.21A | 3uq6B-3l6iA:undetectable | 3uq6B-3l6iA:19.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3loo | ANOPHELES GAMBIAEADENOSINE KINASE (Anophelesgambiae) |
PF00294(PfkB) | 4 | LEU A 16GLY A 63PHE A 168ASN A 296 | B4P A 349 (-4.7A)B4P A 349 ( 3.8A)B4P A 349 (-3.4A)B4P A 349 (-3.6A) | 0.59A | 3uq6B-3looA:46.6 | 3uq6B-3looA:38.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m1u | PUTATIVEGAMMA-D-GLUTAMYL-L-DIAMINO ACIDENDOPEPTIDASE (Desulfovibriovulgaris) |
PF00877(NLPC_P60)PF12912(N_NLPC_P60)PF12913(SH3_6)PF12914(SH3_7) | 4 | LEU A 327GLY A 325PHE A 178ASN A 409 | NoneGOL A 1 ( 3.8A)MES A 14 (-4.1A)None | 1.26A | 3uq6B-3m1uA:undetectable | 3uq6B-3m1uA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m1u | PUTATIVEGAMMA-D-GLUTAMYL-L-DIAMINO ACIDENDOPEPTIDASE (Desulfovibriovulgaris) |
PF00877(NLPC_P60)PF12912(N_NLPC_P60)PF12913(SH3_6)PF12914(SH3_7) | 4 | LEU A 327GLY A 326PHE A 178ASN A 409 | NoneNoneMES A 14 (-4.1A)None | 0.74A | 3uq6B-3m1uA:undetectable | 3uq6B-3m1uA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mix | FLAGELLARBIOSYNTHESIS PROTEINFLHA (Bacillussubtilis) |
PF00771(FHIPEP) | 4 | LEU A 364GLY A 362PHE A 348ASN A 359 | None | 1.22A | 3uq6B-3mixA:undetectable | 3uq6B-3mixA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3naf | CALCIUM-ACTIVATEDPOTASSIUM CHANNELSUBUNITALPHA-1,CALCIUM-ACTIVATED POTASSIUMCHANNEL SUBUNITALPHA-1,CALCIUM-ACTIVATED POTASSIUMCHANNEL SUBUNITALPHA-1 (Homo sapiens) |
PF03493(BK_channel_a) | 4 | LEU A 503GLY A 502PHE A 493ASN A 509 | None | 1.32A | 3uq6B-3nafA:3.3 | 3uq6B-3nafA:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oix | DIHYDROOROTATEOXIDASEPUTATIVEDIHYDROOROTATEDEHYDROGENASE (Streptococcusmutans) |
PF01180(DHO_dh) | 4 | LEU A 101GLY A 47MET A 115ASN A 79 | NoneMLY A 45 ( 3.8A)NoneNone | 1.31A | 3uq6B-3oixA:undetectable | 3uq6B-3oixA:24.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qpc | CUTINASE (Fusarium solani) |
PF01083(Cutinase) | 4 | LEU A 51GLY A 52PHE A 170ASN A 58 | None | 1.14A | 3uq6B-3qpcA:4.2 | 3uq6B-3qpcA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qtp | ENOLASE 1 (Entamoebahistolytica) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | LEU A 161GLY A 217MET A 242PHE A 249 | None | 1.31A | 3uq6B-3qtpA:undetectable | 3uq6B-3qtpA:23.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qtp | ENOLASE 1 (Entamoebahistolytica) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | LEU A 324GLY A 321PHE A 299ASN A 342 | None | 1.30A | 3uq6B-3qtpA:undetectable | 3uq6B-3qtpA:23.13 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3vas | PUTATIVE ADENOSINEKINASE (Schistosomamansoni) |
PF00294(PfkB) | 5 | LEU A 16GLY A 63MET A 134PHE A 169ASN A 298 | ADN A 401 (-4.7A)ADN A 401 ( 3.8A)ADN A 401 ( 4.0A)ADN A 401 (-3.7A)ADN A 401 (-3.7A) | 0.25A | 3uq6B-3vasA:58.8 | 3uq6B-3vasA:99.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3vas | PUTATIVE ADENOSINEKINASE (Schistosomamansoni) |
PF00294(PfkB) | 4 | LEU A 16GLY A 64MET A 134ASN A 298 | ADN A 401 (-4.7A)ADN A 401 (-3.7A)ADN A 401 ( 4.0A)ADN A 401 (-3.7A) | 1.13A | 3uq6B-3vasA:58.8 | 3uq6B-3vasA:99.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cqm | CARBONYL REDUCTASEFAMILY MEMBER 4 (Homo sapiens) |
PF13561(adh_short_C2) | 4 | LEU B 113GLY B 110PHE B 67ASN B 132 | None | 1.17A | 3uq6B-4cqmB:6.2 | 3uq6B-4cqmB:23.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d59 | CELL SURFACE PROTEIN(PUTATIVE CELLSURFACE-ASSOCIATEDCYSTEINE PROTEASE) (Clostridioidesdifficile) |
PF00112(Peptidase_C1) | 4 | LEU A 315GLY A 236PHE A 306ASN A 261 | None | 1.15A | 3uq6B-4d59A:undetectable | 3uq6B-4d59A:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dmm | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]REDUCTASE (Synechococcuselongatus) |
PF13561(adh_short_C2) | 4 | LEU A 123GLY A 120PHE A 77ASN A 142 | None | 1.31A | 3uq6B-4dmmA:7.0 | 3uq6B-4dmmA:28.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dry | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]REDUCTASE (Sinorhizobiummeliloti) |
PF00106(adh_short) | 4 | LEU A 126GLY A 123PHE A 79ASN A 147 | None | 1.32A | 3uq6B-4dryA:5.9 | 3uq6B-4dryA:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e3z | PUTATIVEOXIDOREDUCTASEPROTEIN (Rhizobium etli) |
PF13561(adh_short_C2) | 4 | LEU A 120GLY A 117PHE A 73ASN A 142 | None | 1.27A | 3uq6B-4e3zA:6.8 | 3uq6B-4e3zA:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hzp | BIFUNCTIONALMETHYLMALONYL-COA:ACPACYLTRANSFERASE/DECARBOXYLASE (Streptomycesatroolivaceus) |
no annotation | 4 | LEU A 34GLY A 35PHE A 227ASN A 139 | None | 1.09A | 3uq6B-4hzpA:undetectable | 3uq6B-4hzpA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iqg | SHORT-CHAINDEHYDROGENASE/REDUCTASE SDR (Polaromonas sp.JS666) |
no annotation | 4 | LEU C 118GLY C 115MET C 70ASN C 32 | NoneNoneNoneNAP C 304 (-3.6A) | 1.21A | 3uq6B-4iqgC:2.9 | 3uq6B-4iqgC:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jig | DEHYDROGENASE (Burkholderiacenocepacia) |
PF13561(adh_short_C2) | 4 | LEU A 123GLY A 120MET A 75ASN A 37 | None | 1.16A | 3uq6B-4jigA:6.6 | 3uq6B-4jigA:22.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k3y | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 4 | LEU A 319GLY A 320MET A 353PHE A 384 | None | 1.23A | 3uq6B-4k3yA:undetectable | 3uq6B-4k3yA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ld7 | DIMETHYLALLYLTRYPTOPHAN SYNTHASE (Aspergillusfischeri) |
PF11991(Trp_DMAT) | 4 | LEU A 87GLY A 88PHE A 103ASN A 142 | None | 1.15A | 3uq6B-4ld7A:undetectable | 3uq6B-4ld7A:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ll8 | MYOSIN-4 (Saccharomycescerevisiae) |
PF01843(DIL) | 4 | LEU A1137GLY A1138PHE A1290ASN A1132 | None | 1.03A | 3uq6B-4ll8A:undetectable | 3uq6B-4ll8A:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ozs | ALPHA SOLENOIDPROTEIN (syntheticconstruct) |
PF12854(PPR_1)PF13041(PPR_2) | 4 | LEU A 152GLY A 151PHE A 130ASN A 146 | None | 1.24A | 3uq6B-4ozsA:undetectable | 3uq6B-4ozsA:18.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ppr | PENICILLIN-BINDINGPROTEIN DACB1 (Mycobacteriumtuberculosis) |
PF00768(Peptidase_S11) | 4 | LEU A 172GLY A 171PHE A 243ASN A 267 | None | 1.07A | 3uq6B-4pprA:undetectable | 3uq6B-4pprA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q2w | PUTATIVEENDO-BETA-N-ACETYLGLUCOSAMINIDASE (Streptococcuspneumoniae) |
PF01832(Glucosaminidase) | 4 | LEU A 230GLY A 231PHE A 169ASN A 203 | None | 0.95A | 3uq6B-4q2wA:undetectable | 3uq6B-4q2wA:23.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qg5 | PUTATIVEPHOSPHOGLUCOMUTASE (Leishmaniamajor) |
PF00408(PGM_PMM_IV)PF02878(PGM_PMM_I)PF02879(PGM_PMM_II)PF02880(PGM_PMM_III) | 4 | LEU A 394GLY A 403MET A 379PHE A 332 | None | 1.24A | 3uq6B-4qg5A:undetectable | 3uq6B-4qg5A:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r3a | BLUE-LIGHT-ACTIVATEDHISTIDINE KINASE 2 (Erythrobacterlitoralis) |
PF07568(HisKA_2)PF13426(PAS_9)PF13581(HATPase_c_2) | 4 | LEU A 20GLY A 116PHE A 18ASN A 97 | NoneRBF A 402 ( 3.8A)NoneRBF A 402 (-4.0A) | 1.25A | 3uq6B-4r3aA:undetectable | 3uq6B-4r3aA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rye | D-ALANYL-D-ALANINECARBOXYPEPTIDASE (Mycobacteriumtuberculosis) |
PF00768(Peptidase_S11) | 4 | LEU A 120GLY A 119PHE A 193ASN A 215 | None | 1.18A | 3uq6B-4ryeA:undetectable | 3uq6B-4ryeA:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s1a | UNCHARACTERIZEDPROTEIN (Ruminiclostridiumthermocellum) |
PF13200(DUF4015) | 4 | LEU A 287GLY A 284PHE A 240ASN A 263 | None | 1.29A | 3uq6B-4s1aA:undetectable | 3uq6B-4s1aA:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4umv | ZINC-TRANSPORTINGATPASE (Shigella sonnei) |
PF00122(E1-E2_ATPase)PF00702(Hydrolase) | 4 | LEU A 597GLY A 598PHE A 435ASN A 573 | None | 1.14A | 3uq6B-4umvA:undetectable | 3uq6B-4umvA:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y63 | HISTO-BLOOD GROUPABO SYSTEMTRANSFERASE (Homo sapiens) |
PF03414(Glyco_transf_6) | 4 | LEU A 118GLY A 117MET A 142PHE A 269 | None | 1.24A | 3uq6B-4y63A:undetectable | 3uq6B-4y63A:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z64 | PHYTOSULFOKINERECEPTOR 1 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13855(LRR_8) | 4 | LEU A 530GLY A 531PHE A 552ASN A 581 | None | 1.01A | 3uq6B-4z64A:undetectable | 3uq6B-4z64A:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zhj | MG-CHELATASE SUBUNITCHLH (Synechocystissp. PCC 6803) |
PF02514(CobN-Mg_chel)PF11965(DUF3479) | 4 | LEU A 624GLY A 469PHE A 626ASN A 657 | None | 1.21A | 3uq6B-4zhjA:2.8 | 3uq6B-4zhjA:15.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zwe | DEOXYNUCLEOSIDETRIPHOSPHATETRIPHOSPHOHYDROLASESAMHD1 (Homo sapiens) |
PF01966(HD) | 4 | LEU A 150GLY A 151PHE A 157ASN A 380 | NoneNoneDGT A 702 (-3.5A)None | 1.06A | 3uq6B-4zweA:undetectable | 3uq6B-4zweA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zwe | DEOXYNUCLEOSIDETRIPHOSPHATETRIPHOSPHOHYDROLASESAMHD1 (Homo sapiens) |
PF01966(HD) | 4 | LEU A 150GLY A 152PHE A 157ASN A 380 | NoneNoneDGT A 702 (-3.5A)None | 1.29A | 3uq6B-4zweA:undetectable | 3uq6B-4zweA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ao0 | DEOXYNUCLEOSIDETRIPHOSPHATETRIPHOSPHOHYDROLASESAMHD1 (Homo sapiens) |
PF01966(HD) | 4 | LEU A 150GLY A 151PHE A 157ASN A 380 | NoneNoneNoneDG3 A2001 (-3.2A) | 1.01A | 3uq6B-5ao0A:undetectable | 3uq6B-5ao0A:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ao0 | DEOXYNUCLEOSIDETRIPHOSPHATETRIPHOSPHOHYDROLASESAMHD1 (Homo sapiens) |
PF01966(HD) | 4 | LEU A 150GLY A 152PHE A 157ASN A 380 | NoneNoneNoneDG3 A2001 (-3.2A) | 1.24A | 3uq6B-5ao0A:undetectable | 3uq6B-5ao0A:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b04 | PROBABLE TRANSLATIONINITIATION FACTOREIF-2B SUBUNITEPSILON (Schizosaccharomycespombe) |
PF00132(Hexapep)PF00483(NTP_transferase) | 4 | LEU I 256GLY I 250MET I 155PHE I 234 | None | 1.23A | 3uq6B-5b04I:2.3 | 3uq6B-5b04I:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cb2 | PROTEIN SEY1 (Candidaalbicans) |
PF05879(RHD3) | 4 | LEU A 269GLY A 270PHE A 262ASN A 80 | None | 1.31A | 3uq6B-5cb2A:undetectable | 3uq6B-5cb2A:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5da0 | SULPHATE TRANSPORTER (Deinococcusgeothermalis) |
PF00916(Sulfate_transp)PF01740(STAS) | 4 | LEU A 345GLY A 343MET A 359ASN A 133 | None | 1.28A | 3uq6B-5da0A:undetectable | 3uq6B-5da0A:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dll | AMINOPEPTIDASE N (Francisellatularensis) |
PF01433(Peptidase_M1)PF11940(DUF3458)PF17432(DUF3458_C) | 4 | LEU A 780GLY A 783MET A 802ASN A 823 | None | 1.24A | 3uq6B-5dllA:undetectable | 3uq6B-5dllA:17.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e5b | FACT COMPLEX SUBUNITSPT16 (Homo sapiens) |
PF00557(Peptidase_M24)PF14826(FACT-Spt16_Nlob) | 4 | LEU A 381GLY A 382MET A 330PHE A 304 | None | 1.30A | 3uq6B-5e5bA:undetectable | 3uq6B-5e5bA:23.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ehd | NUCLEOPHOSMIN (Homo sapiens) |
PF03066(Nucleoplasmin) | 4 | LEU A 44GLY A 113PHE A 31ASN A 16 | None | 1.16A | 3uq6B-5ehdA:undetectable | 3uq6B-5ehdA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gr8 | LEUCINE-RICH REPEATRECEPTOR-LIKEPROTEIN KINASE PEPR1 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13855(LRR_8) | 4 | LEU A 466GLY A 467PHE A 488ASN A 516 | None | 0.99A | 3uq6B-5gr8A:undetectable | 3uq6B-5gr8A:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iof | SULPHATE TRANSPORTER (Deinococcusgeothermalis) |
PF00916(Sulfate_transp) | 4 | LEU A 345GLY A 343MET A 359ASN A 133 | None | 1.28A | 3uq6B-5iofA:undetectable | 3uq6B-5iofA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iwh | ENDORIBONUCLEASEHIGB (Proteusvulgaris) |
PF05015(HigB-like_toxin) | 4 | LEU A 12GLY A 17PHE A 5ASN A 31 | None | 1.20A | 3uq6B-5iwhA:undetectable | 3uq6B-5iwhA:15.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k0u | CAPSID PROTEIN VP2CAPSID PROTEIN VP3 (Rhinovirus C) |
PF00073(Rhv) | 4 | LEU C 183GLY C 184MET B 67PHE C 176 | None | 1.31A | 3uq6B-5k0uC:undetectable | 3uq6B-5k0uC:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m0t | ALPHA-KETOGLUTARATE-DEPENDENT NON-HEMEIRON OXYGENASE EASH (Aspergillusjaponicus) |
PF05721(PhyH) | 4 | LEU A 99GLY A 98MET A 228PHE A 38 | None | 1.16A | 3uq6B-5m0tA:undetectable | 3uq6B-5m0tA:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mlz | DOLICHOLMONOPHOSPHATEMANNOSE SYNTHASE (Pyrococcusfuriosus) |
PF00535(Glycos_transf_2)PF04138(GtrA) | 4 | LEU A 242GLY A 244PHE A 338ASN A 281 | NoneLDA A 408 (-4.6A)NoneNone | 1.20A | 3uq6B-5mlzA:undetectable | 3uq6B-5mlzA:24.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mqs | BETA-L-ARABINOBIOSIDASE (Bacteroidesthetaiotaomicron) |
PF13088(BNR_2) | 4 | LEU A1030GLY A1029PHE A1055ASN A1044 | None | 1.10A | 3uq6B-5mqsA:undetectable | 3uq6B-5mqsA:17.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u1d | ANTIGEN PEPTIDETRANSPORTER 1TAP TRANSPORTERINHIBITOR ICP47 (Homo sapiens;Humanalphaherpesvirus1) |
PF00005(ABC_tran)PF00664(ABC_membrane)PF05363(Herpes_US12) | 4 | LEU A 422GLY A 419PHE A 339ASN X 14 | None | 0.93A | 3uq6B-5u1dA:undetectable | 3uq6B-5u1dA:17.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5usf | TYROSYL-TRNASYNTHETASE, PUTATIVE (Leishmaniadonovani) |
PF00579(tRNA-synt_1b) | 4 | LEU A 181GLY A 182PHE A 39ASN A 56 | YSA A 701 (-3.6A)YSA A 701 (-3.3A)YSA A 701 (-4.6A)None | 1.22A | 3uq6B-5usfA:undetectable | 3uq6B-5usfA:20.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x3e | KINESIN-LIKE PROTEIN (Caenorhabditiselegans) |
PF00225(Kinesin) | 4 | LEU A 326GLY A 328PHE A 419ASN A 349 | None | 1.24A | 3uq6B-5x3eA:undetectable | 3uq6B-5x3eA:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c2j | RNAP1 (Escherichiavirus N4) |
no annotation | 4 | LEU A 124GLY A 245PHE A 229ASN A 256 | None | 1.09A | 3uq6B-6c2jA:undetectable | 3uq6B-6c2jA:11.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f42 | DNA-DIRECTED RNAPOLYMERASE IIISUBUNIT RPC2 (Saccharomycescerevisiae) |
no annotation | 4 | LEU B 961GLY B 964PHE B1019ASN B 754 | None | 1.24A | 3uq6B-6f42B:undetectable | 3uq6B-6f42B:12.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fae | ADP-RIBOSYLATIONFACTOR 1 (Homo sapiens) |
no annotation | 4 | LEU B 145GLY B 144PHE B 90ASN B 101 | None | 1.31A | 3uq6B-6faeB:undetectable | 3uq6B-6faeB:13.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fn1 | HUMAN-MOUSE CHIMERICABCB1 (ABCBHM) (Homo sapiens) |
no annotation | 4 | LEU A 883GLY A 880MET A 191PHE A 941 | None | 1.03A | 3uq6B-6fn1A:undetectable | 3uq6B-6fn1A:12.57 |