SIMILAR PATTERNS OF AMINO ACIDS FOR 3UPR_A_1KXA277

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ed3 CLASS I MAJOR
HISTOCOMPATIBILITY
ANTIGEN RT1-AA

(Rattus
norvegicus) 		PF00129
(MHC_I)
PF07654
(C1-set) 		7 TYR A   9
TYR A  74
ILE A  95
TYR A  99
TYR A 123
ILE A 124
TRP A 147
 None
 0.54A 3uprA-1ed3A:
33.9		 3uprA-1ed3A:
74.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1nez H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, TLA(C)
ALPHA CHAIN

(Mus musculus) 		PF00129
(MHC_I)
PF07654
(C1-set) 		7 TYR A   9
ILE A  95
VAL A  97
TYR A  99
TYR A 123
ILE A 124
TRP A 147
 None
 0.54A 3uprA-1nezA:
28.5		 3uprA-1nezA:
66.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1poi GLUTACONATE COENZYME
A-TRANSFERASE

(Acidaminococcus
fermentans) 		PF01144
(CoA_trans) 		5 TYR A 207
ILE A 209
VAL A 175
ASP A  19
ILE A  44
 None
 1.45A 3uprA-1poiA:
undetectable		 3uprA-1poiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rq1 HYPOTHETICAL 65.0
KDA PROTEIN IN
COX14-COS3
INTERGENIC REGION
PRECURSOR

(Saccharomyces
cerevisiae) 		PF04137
(ERO1) 		5 TYR A 224
TYR A 204
ILE A 203
VAL A 227
ILE A 234
 None
FAD  A 634 (-4.7A)
None
None
FAD  A 634 (-4.0A)
 1.47A 3uprA-1rq1A:
undetectable		 3uprA-1rq1A:
20.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1s7s H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, K-B ALPHA
CHAIN

(Mus musculus) 		PF00129
(MHC_I)
PF07654
(C1-set) 		5 ILE A  95
VAL A  97
TYR A 123
ILE A 124
TRP A 147
 None
 0.28A 3uprA-1s7sA:
34.1		 3uprA-1s7sA:
70.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tmc CLASS I
HISTOCOMPATIBILITY
ANTIGEN (HLA-AW68)

(Homo sapiens) 		PF00129
(MHC_I) 		6 TYR A   9
ILE A  95
TYR A  99
TYR A 123
ILE A 124
TRP A 147
 None
 0.49A 3uprA-1tmcA:
28.1		 3uprA-1tmcA:
81.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xdp POLYPHOSPHATE KINASE

(Escherichia
coli) 		PF02503
(PP_kinase)
PF13089
(PP_kinase_N)
PF13090
(PP_kinase_C) 		5 TYR A 596
ILE A 597
VAL A 595
ASP A 593
ILE A 640
 None
 1.49A 3uprA-1xdpA:
undetectable		 3uprA-1xdpA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jjq UNCHARACTERIZED RNA
METHYLTRANSFERASE
PYRAB10780

(Pyrococcus
abyssi) 		PF05958
(tRNA_U5-meth_tr) 		5 TYR A 174
VAL A 191
SER A 212
TYR A 210
ILE A 225
 None
 1.11A 3uprA-2jjqA:
undetectable		 3uprA-2jjqA:
20.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE

(Mus musculus) 		PF00129
(MHC_I)
PF07654
(C1-set) 		5 ILE H  95
VAL H  97
TYR H 123
ILE H 124
TRP H 147
 None
 0.31A 3uprA-2ol3H:
30.8		 3uprA-2ol3H:
71.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qri H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN K-B ALPHA
CHAIN, BETA-2
MICROGLOBULIN,
OVALBUMIN-DERIVED
PEPTIDE

(Mus musculus) 		PF00129
(MHC_I)
PF07654
(C1-set) 		5 ILE A  95
VAL A  97
TYR A 123
ILE A 124
TRP A 147
 None
 0.32A 3uprA-2qriA:
29.0		 3uprA-2qriA:
55.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r7y RIBONUCLEASE H

(Bacillus
halodurans) 		no annotation 5 TYR A 119
ILE A 129
ASP A  87
SER A  69
TYR A 130
 None
 1.18A 3uprA-2r7yA:
undetectable		 3uprA-2r7yA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vx4 CELLVIBRIO JAPONICUS
MANNANASE CJMAN26C

(Cellvibrio
japonicus) 		PF02156
(Glyco_hydro_26) 		5 TYR A 263
ILE A 291
VAL A 289
ASP A 286
TYR A  69
 None
 1.42A 3uprA-2vx4A:
undetectable		 3uprA-2vx4A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w8s PHOSPHONATE
MONOESTER HYDROLASE

(Paraburkholderia
caryophylli) 		PF00884
(Sulfatase)
PF16347
(DUF4976) 		5 TYR A 199
ILE A 103
VAL A 135
SER A 134
ILE A 128
 None
 1.46A 3uprA-2w8sA:
undetectable		 3uprA-2w8sA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE

(Vibrio cholerae) 		PF01979
(Amidohydro_1) 		5 TYR A 375
TYR A   2
ILE A  23
VAL A 370
ILE A 349
 None
 1.41A 3uprA-3egjA:
undetectable		 3uprA-3egjA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gpr RHODOCETIN SUBUNIT
BETA

(Calloselasma
rhodostoma) 		PF00059
(Lectin_C) 		5 TYR B2066
ILE B2057
VAL B2101
TYR B2111
ILE B2044
 None
 1.50A 3uprA-3gprB:
undetectable		 3uprA-3gprB:
16.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3jts MHC CLASS I
MAMU-A*02

(Macaca mulatta) 		PF00129
(MHC_I)
PF07654
(C1-set) 		7 TYR A   9
ILE A  95
TYR A  99
SER A 116
TYR A 123
ILE A 124
TRP A 147
 None
 0.83A 3uprA-3jtsA:
32.8		 3uprA-3jtsA:
86.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mbw EPHRIN-A1

(Homo sapiens) 		PF00812
(Ephrin) 		5 ILE B  39
VAL B 145
TYR B 127
ILE B  49
TRP B  25
 None
 1.38A 3uprA-3mbwB:
undetectable		 3uprA-3mbwB:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3of7 REGULATOR OF
CHROMOSOME
CONDENSATION

(Saccharomyces
cerevisiae) 		PF00415
(RCC1)
PF13540
(RCC1_2) 		5 ILE A 223
VAL A 186
TYR A 187
ILE A 233
TRP A 245
 None
 1.32A 3uprA-3of7A:
undetectable		 3uprA-3of7A:
20.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3pwv MHC CLASS I ANTIGEN

(Bos taurus) 		PF00129
(MHC_I)
PF07654
(C1-set) 		5 TYR A   8
TYR A  98
TYR A 122
ILE A 123
TRP A 146
 None
 0.22A 3uprA-3pwvA:
34.2		 3uprA-3pwvA:
79.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3qq3 MHC CLASS I ANTIGEN

(Sus scrofa) 		PF00129
(MHC_I)
PF07654
(C1-set) 		6 TYR A   9
TYR A  74
TYR A  99
TYR A 123
ILE A 124
TRP A 147
 None
 0.26A 3uprA-3qq3A:
33.8		 3uprA-3qq3A:
74.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3rl2 HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, A-3 ALPHA
CHAIN

(Homo sapiens) 		PF00129
(MHC_I)
PF07654
(C1-set) 		5 ILE A  95
TYR A  99
TYR A 123
ILE A 124
TRP A 147
 None
 0.35A 3uprA-3rl2A:
31.5		 3uprA-3rl2A:
87.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3rwg MAJOR
HISTOCOMPATIBILITY
COMPLEX CLASS I

(Macaca mulatta) 		PF00129
(MHC_I)
PF07654
(C1-set) 		7 TYR A   9
ILE A  95
TYR A  99
SER A 116
TYR A 123
ILE A 124
TRP A 147
 None
 0.35A 3uprA-3rwgA:
34.0		 3uprA-3rwgA:
85.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s9j MEMBER OF DUF4221
FAMILY

(Bacteroides
vulgatus) 		PF13970
(DUF4221) 		5 TYR A 305
ILE A 332
VAL A 331
SER A 330
TYR A 265
 None
 1.47A 3uprA-3s9jA:
undetectable		 3uprA-3s9jA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wau 4-O-BETA-D-MANNOSYL-
D-GLUCOSE
PHOSPHORYLASE

(Bacteroides
fragilis) 		PF04041
(Glyco_hydro_130) 		5 ILE A 107
VAL A 349
TYR A 340
TYR A  83
ILE A 329
 None
 1.26A 3uprA-3wauA:
undetectable		 3uprA-3wauA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e2o ALPHA-AMYLASE

(Geobacillus
thermoleovorans) 		PF00128
(Alpha-amylase) 		5 TYR A 351
ILE A 355
TYR A 350
ASP A 311
ILE A 333
 None
 1.43A 3uprA-4e2oA:
undetectable		 3uprA-4e2oA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gah THIOESTERASE
SUPERFAMILY MEMBER 4

(Homo sapiens) 		PF03061
(4HBT) 		5 ILE A 188
VAL A 214
SER A 224
TYR A 184
ILE A 182
 None
 1.07A 3uprA-4gahA:
undetectable		 3uprA-4gahA:
18.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4lcy HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-46 ALPHA
CHAIN

(Homo sapiens) 		PF00129
(MHC_I)
PF07654
(C1-set) 		6 TYR A   9
TYR A  99
ASP A 114
TYR A 123
ILE A 124
TRP A 147
 None
 0.36A 3uprA-4lcyA:
34.2		 3uprA-4lcyA:
93.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qt9 PUTATIVE
GLUCOAMYLASE

(Bacteroides
caccae) 		PF10091
(Glycoamylase) 		5 TYR A 179
TYR A 180
ILE A 190
VAL A 176
ILE A 126
 None
 1.44A 3uprA-4qt9A:
undetectable		 3uprA-4qt9A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uy4 SPINDLIN-4

(Homo sapiens) 		PF02513
(Spin-Ssty) 		5 ILE A  76
ASP A  92
TYR A  85
ILE A 228
TRP A  49
 None
 1.28A 3uprA-4uy4A:
undetectable		 3uprA-4uy4A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ah5 LEUCINE--TRNA LIGASE

(Agrobacterium
tumefaciens) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1)
PF13603
(tRNA-synt_1_2) 		5 TYR A 500
TYR A  34
ILE A 517
TYR A 496
ILE A 550
 None
 1.32A 3uprA-5ah5A:
undetectable		 3uprA-5ah5A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e9u GLYCOSYLTRANSFERASE-
STABILIZING PROTEIN
GTF2

(Streptococcus
gordonii) 		no annotation 5 ILE B  31
VAL B  30
TYR B   8
SER B  43
TYR B  45
 None
 1.44A 3uprA-5e9uB:
undetectable		 3uprA-5e9uB:
20.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5f1n MHC CLASS I ANTIGEN

(Canis lupus) 		PF00129
(MHC_I)
PF07654
(C1-set) 		7 TYR A   9
TYR A  74
ILE A  95
TYR A  99
TYR A 123
ILE A 124
TRP A 147
 None
 0.38A 3uprA-5f1nA:
33.4		 3uprA-5f1nA:
80.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fm5 MYOMESIN-1

(Homo sapiens) 		PF00041
(fn3) 		5 ILE M 528
VAL M 516
SER M 599
ILE M 581
TRP M 556
 None
 0.95A 3uprA-5fm5M:
undetectable		 3uprA-5fm5M:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fm8 MYOMESIN-1

(Homo sapiens) 		PF00041
(fn3) 		5 ILE A 528
VAL A 516
SER A 599
ILE A 581
TRP A 556
 None
 0.98A 3uprA-5fm8A:
3.8		 3uprA-5fm8A:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5guh PIWI

(Bombyx mori) 		PF02170
(PAZ)
PF02171
(Piwi) 		5 TYR A 738
ILE A 777
VAL A 778
SER A 779
ILE A 782
 None
 1.42A 3uprA-5guhA:
undetectable		 3uprA-5guhA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hh7 ORIGIN OF
REPLICATION COMPLEX
SUBUNIT 1B

(Arabidopsis
thaliana) 		PF00628
(PHD)
PF01426
(BAH) 		5 ILE A 252
VAL A 148
TYR A 149
ILE A 299
TRP A 270
 None
 1.40A 3uprA-5hh7A:
undetectable		 3uprA-5hh7A:
18.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5j6g H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN

(Mus musculus) 		PF00129
(MHC_I)
PF07654
(C1-set) 		5 ILE A  95
TYR A  99
TYR A 123
ILE A 124
TRP A 147
 None
 0.31A 3uprA-5j6gA:
32.6		 3uprA-5j6gA:
75.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lpc VANADIUM-DEPENDENT
BROMOPEROXIDASE

(Acaryochloris
marina) 		no annotation 5 TYR A 369
TYR A 359
SER A 585
TYR A 599
ILE A 586
 None
 1.50A 3uprA-5lpcA:
undetectable		 3uprA-5lpcA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ly6 PNEUMOLYSIN

(Streptococcus
pneumoniae) 		PF01289
(Thiol_cytolysin)
PF17440
(Thiol_cytolys_C) 		5 TYR B 242
TYR B 200
VAL B 202
TYR B  71
SER B 203
 None
 1.30A 3uprA-5ly6B:
undetectable		 3uprA-5ly6B:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii) 		PF12765
(Cohesin_HEAT)
PF12830
(Nipped-B_C) 		5 TYR A 795
ILE A 800
VAL A 796
TYR A 758
ILE A 782
 None
 1.42A 3uprA-5me3A:
undetectable		 3uprA-5me3A:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mu7 COATOMER SUBUNIT
DELTA-LIKE PROTEIN

(Chaetomium
thermophilum) 		PF01217
(Clat_adaptor_s) 		5 TYR B  58
ILE B  69
VAL B  67
TYR B  65
SER B   7
 None
 0.98A 3uprA-5mu7B:
undetectable		 3uprA-5mu7B:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tta PUTATIVE EXPORTED
PROTEIN

(Clostridioides
difficile) 		no annotation 5 TYR A 252
ILE A 103
SER A 234
ILE A 232
TRP A 119
 None
 1.44A 3uprA-5ttaA:
2.0		 3uprA-5ttaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uam ULVAN LYASE-PL25

(Pseudoalteromonas
sp. PLSV) 		PF15892
(BNR_4) 		5 TYR A 188
ILE A  64
TYR A 246
ASP A 262
ILE A 345
 EDO  A 511 ( 3.0A)
K  A 505 (-4.0A)
EDO  A 511 ( 3.8A)
None
None
 1.26A 3uprA-5uamA:
undetectable		 3uprA-5uamA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uwv L,D-TRANSPEPTIDASE 2

(Mycobacteroides
abscessus) 		no annotation 5 TYR B 289
ILE B 291
VAL B 372
SER B 252
ILE B 263
 None
 0.97A 3uprA-5uwvB:
3.8		 3uprA-5uwvB:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wpk 3-HYDROXY-3-METHYLGL
UTARYL COENZYME A
REDUCTASE

(Streptococcus
pneumoniae) 		no annotation 5 TYR A  73
ILE A 357
VAL A  66
SER A  92
ILE A  95
 None
 1.44A 3uprA-5wpkA:
undetectable		 3uprA-5wpkA:
15.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5xmm MHC CLASS I ANTIGEN
ALPHA CHAIN

(Felis catus) 		no annotation 6 TYR A  10
ILE A  96
TYR A 100
TYR A 124
ILE A 125
TRP A 148
 None
 0.47A 3uprA-5xmmA:
33.7		 3uprA-5xmmA:
37.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6avf HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-7 ALPHA
CHAIN

(Homo sapiens) 		no annotation 6 TYR H   9
TYR H  99
ASP H 114
TYR H 123
ILE H 124
TRP H 147
 None
 0.43A 3uprA-6avfH:
33.6		 3uprA-6avfH:
65.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6avo PROTEASOME SUBUNIT
BETA TYPE-10

(Homo sapiens) 		no annotation 5 ILE B  37
VAL B 100
TYR B 111
TYR B  42
ILE B 178
 None
 1.27A 3uprA-6avoB:
undetectable		 3uprA-6avoB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bfu SPIKE PROTEIN

(Coronavirus
HKU15) 		no annotation 5 ILE A 573
VAL A 571
TYR A 567
ASP A 568
TYR A 967
 None
 1.26A 3uprA-6bfuA:
undetectable		 3uprA-6bfuA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ces RAS-RELATED
GTP-BINDING PROTEIN
C

(Homo sapiens) 		no annotation 5 TYR C 142
ILE C 141
VAL C 143
ASP C 145
ILE C  77
 None
 1.41A 3uprA-6cesC:
undetectable		 3uprA-6cesC:
15.73