SIMILAR PATTERNS OF AMINO ACIDS FOR 3UJ7_B_SAMB302_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a6d | THERMOSOME (BETASUBUNIT) (Thermoplasmaacidophilum) |
PF00118(Cpn60_TCP1) | 5 | LEU B 105GLY B 125ILE B 511ARG B 430ALA B 434 | None | 1.11A | 3uj7B-1a6dB:undetectable | 3uj7B-1a6dB:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dm3 | BIOSYNTHETICTHIOLASE ACETYLATEDAT CYS89 (Zoogloearamigera) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | LEU A 258ILE A 269GLY A 273ILE A 275LEU A 358 | None | 1.04A | 3uj7B-1dm3A:undetectable | 3uj7B-1dm3A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e6v | METHYL-COENZYME MREDUCTASE I ALPHASUBUNIT (Methanopyruskandleri) |
PF02249(MCR_alpha)PF02745(MCR_alpha_N) | 5 | GLY A 429GLY A 426ILE A 494ALA A 377LEU A 436 | None | 1.13A | 3uj7B-1e6vA:undetectable | 3uj7B-1e6vA:16.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e6y | METHYL-COENZYME MREDUCTASE SUBUNITALPHA (Methanosarcinabarkeri) |
PF02249(MCR_alpha)PF02745(MCR_alpha_N) | 5 | GLY A1446GLY A1443ILE A1511ALA A1394LEU A1453 | None | 1.22A | 3uj7B-1e6yA:undetectable | 3uj7B-1e6yA:18.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ebl | BETA-KETOACYL-ACPSYNTHASE III (Escherichiacoli) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 5 | LEU A 22GLY A 158GLY A 273ILE A 39ALA A 143 | None | 1.11A | 3uj7B-1eblA:undetectable | 3uj7B-1eblA:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mf1 | ADENYLOSUCCINATESYNTHETASE (Mus musculus) |
PF00709(Adenylsucc_synt) | 5 | LEU A 128ILE A 59GLY A 99ILE A 130LEU A 84 | None | 0.90A | 3uj7B-1mf1A:undetectable | 3uj7B-1mf1A:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mro | METHYL-COENZYME MREDUCTASE (Methanothermobactermarburgensis) |
PF02249(MCR_alpha)PF02745(MCR_alpha_N) | 5 | GLY A 426GLY A 423ILE A 491ALA A 374LEU A 433 | None | 1.15A | 3uj7B-1mroA:undetectable | 3uj7B-1mroA:17.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nt4 | GLUCOSE-1-PHOSPHATASE (Escherichiacoli) |
PF00328(His_Phos_2) | 5 | LEU A 366ILE A 337ILE A 371ASP A 380LEU A 273 | None | 1.07A | 3uj7B-1nt4A:undetectable | 3uj7B-1nt4A:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q1r | PUTIDAREDOXINREDUCTASE (Pseudomonasputida) |
PF07992(Pyr_redox_2)PF14759(Reductase_C) | 5 | LEU A 152ILE A 155GLY A 161GLY A 156LEU A 53 | None | 1.19A | 3uj7B-1q1rA:2.6 | 3uj7B-1q1rA:19.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sq7 | TRIOSEPHOSPHATEISOMERASE (Gallus gallus) |
PF00121(TIM) | 5 | ILE A 83ILE A 46ILE A 78ALA A 43LEU A 21 | None | 1.14A | 3uj7B-1sq7A:undetectable | 3uj7B-1sq7A:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tdt | TETRAHYDRODIPICOLINATE-N-SUCCINYLTRANSFERASE (Mycobacteriumbovis) |
PF00132(Hexapep)PF14602(Hexapep_2)PF14805(THDPS_N_2) | 5 | LEU A 59ILE A 130GLY A 36GLY A 114LEU A 4 | None | 1.16A | 3uj7B-1tdtA:undetectable | 3uj7B-1tdtA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vlu | GAMMA-GLUTAMYLPHOSPHATE REDUCTASE (Saccharomycescerevisiae) |
PF00171(Aldedh) | 5 | ILE A 246ILE A 266ILE A 232ASP A 239ALA A 238 | None | 1.18A | 3uj7B-1vluA:4.1 | 3uj7B-1vluA:19.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xq1 | PUTATIVE TROPINONEREDUCATSE (Arabidopsisthaliana) |
PF13561(adh_short_C2) | 5 | GLY A 22GLY A 27ILE A 41ILE A 30LEU A 55 | None | 1.20A | 3uj7B-1xq1A:7.0 | 3uj7B-1xq1A:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yr2 | PROLYLOLIGOPEPTIDASE (Novosphingobiumcapsulatum) |
PF00326(Peptidase_S9)PF02897(Peptidase_S9_N) | 5 | LEU A 522ILE A 406GLY A 407ASP A 383ALA A 384 | None | 1.20A | 3uj7B-1yr2A:undetectable | 3uj7B-1yr2A:15.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z9a | NAD(P)H-DEPENDENTD-XYLOSE REDUCTASE ([Candida]tenuis) |
PF00248(Aldo_ket_red) | 5 | ILE A 147ILE A 166ILE A 113ARG A 181ALA A 183 | None | 0.96A | 3uj7B-1z9aA:undetectable | 3uj7B-1z9aA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ae0 | MEMBRANE-BOUND LYTICMUREINTRANSGLYCOSYLASE A (Escherichiacoli) |
PF03562(MltA)PF06725(3D) | 5 | GLY X 37ILE X 43ARG X 255ALA X 256LEU X 296 | None | 1.20A | 3uj7B-2ae0X:undetectable | 3uj7B-2ae0X:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d7m | FILAMIN-C (Homo sapiens) |
PF00630(Filamin) | 5 | LEU A 46GLY A 90ILE A 86ASP A 10ALA A 11 | None | 1.20A | 3uj7B-2d7mA:undetectable | 3uj7B-2d7mA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hm2 | PYRIN-ONLY PROTEIN 1 (Homo sapiens) |
PF02758(PYRIN) | 5 | LEU Q 27GLY Q 45GLY Q 42ASP Q 51LEU Q 20 | None | 1.10A | 3uj7B-2hm2Q:undetectable | 3uj7B-2hm2Q:16.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o57 | PUTATIVE SARCOSINEDIMETHYLGLYCINEMETHYLTRANSFERASE (Galdieriasulphuraria) |
PF08241(Methyltransf_11) | 5 | GLY A 90GLY A 92ASP A 158ALA A 159HIS A 162 | None | 0.63A | 3uj7B-2o57A:27.3 | 3uj7B-2o57A:28.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o57 | PUTATIVE SARCOSINEDIMETHYLGLYCINEMETHYLTRANSFERASE (Galdieriasulphuraria) |
PF08241(Methyltransf_11) | 5 | GLY A 90GLY A 92ILE A 113ASP A 158ALA A 159 | None | 0.41A | 3uj7B-2o57A:27.3 | 3uj7B-2o57A:28.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2px5 | GENOME POLYPROTEIN[CONTAINS: CAPSIDPROTEIN C (COREPROTEIN) ENVELOPE PROTEIN M(MATRIX PROTEIN) MAJOR ENVELOPEPROTEIN E NON-STRUCTURALPROTEIN 1 (NS1) NON-STRUCTURALPROTEIN 2A (NS2A) FLAVIVIRIN PROTEASENS2B REGULATORYSUBUNIT FLAVIVIRIN PROTEASENS3 CATALYTICSUBUNIT NON-STRUCTURALPROTEIN 4A (NS4A) NON-STRUCTURALPROTEIN 4B (NS4B) RNA-DIRECTED RNAPOLYMERASE (EC2.7.7.48) (NS5)] (Murray Valleyencephalitisvirus) |
PF01728(FtsJ) | 5 | GLY A 148ILE A 181CYH A 145ILE A 147LEU A 195 | NoneNoneNoneSAH A 500 ( 4.3A)None | 0.93A | 3uj7B-2px5A:8.8 | 3uj7B-2px5A:23.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v40 | ADENYLOSUCCINATESYNTHETASE ISOZYME 2 (Homo sapiens) |
PF00709(Adenylsucc_synt) | 5 | LEU A 127ILE A 56GLY A 96ILE A 129LEU A 81 | None | 0.85A | 3uj7B-2v40A:undetectable | 3uj7B-2v40A:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2var | FRUCTOKINASE (Sulfolobussolfataricus) |
PF00294(PfkB) | 5 | LEU A 11ILE A 79GLY A 57ILE A 65ALA A 112 | KDG A1313 ( 4.7A)NoneNoneNoneNone | 1.00A | 3uj7B-2varA:3.7 | 3uj7B-2varA:25.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wnr | PROBABLE EXOSOMECOMPLEX EXONUCLEASE1 (Methanothermobacterthermautotrophicus) |
PF01138(RNase_PH)PF03725(RNase_PH_C) | 5 | ILE B 127ILE B 31ILE B 52ALA B 147LEU B 234 | None | 1.09A | 3uj7B-2wnrB:undetectable | 3uj7B-2wnrB:22.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zau | SELENIDE, WATERDIKINASE (Aquifexaeolicus) |
PF00586(AIRS)PF02769(AIRS_C) | 5 | LEU A 81GLY A 73ARG A 115ASP A 119ALA A 117 | None | 1.12A | 3uj7B-2zauA:undetectable | 3uj7B-2zauA:24.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ckb | SUSD (Bacteroidesthetaiotaomicron) |
PF07980(SusD_RagB) | 5 | LEU A 435GLY A 216ILE A 286ILE A 282LEU A 158 | None | 1.22A | 3uj7B-3ckbA:undetectable | 3uj7B-3ckbA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d7r | ESTERASE (Staphylococcusaureus) |
PF07859(Abhydrolase_3) | 5 | LEU A 176ILE A 130GLY A 154ALA A 156LEU A 183 | None | 1.20A | 3uj7B-3d7rA:2.8 | 3uj7B-3d7rA:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dni | DEOXYRIBONUCLEASE I (Bos taurus) |
PF03372(Exo_endo_phos) | 5 | LEU A 81ILE A 25GLY A 12ILE A 8ALA A 47 | None | 0.85A | 3uj7B-3dniA:undetectable | 3uj7B-3dniA:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eeh | PUTATIVE LIGHT ANDREDOX SENSINGHISTIDINE KINASE (Haloarculamarismortui) |
PF08447(PAS_3) | 5 | ILE A 37GLY A 119ILE A 102ILE A 23LEU A 78 | NoneNonePG5 A 126 ( 4.4A)NoneNone | 0.89A | 3uj7B-3eehA:undetectable | 3uj7B-3eehA:18.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fk5 | 3-OXOACYL-SYNTHASEIII (Xanthomonasoryzae) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 5 | LEU A 108ILE A 78ILE A 83ASP A 75ALA A 72 | None | 1.14A | 3uj7B-3fk5A:undetectable | 3uj7B-3fk5A:24.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ga2 | ENDONUCLEASE V (Bacillussubtilis) |
PF04493(Endonuclease_5) | 5 | ILE A 143GLY A 44ILE A 65ASP A 223ALA A 222 | None | 1.18A | 3uj7B-3ga2A:undetectable | 3uj7B-3ga2A:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gcz | POLYPROTEIN (Yokose virus) |
PF01728(FtsJ) | 5 | GLY A 148ILE A 182CYH A 145ILE A 147LEU A 196 | NoneNoneNoneSAM A4633 ( 4.2A)None | 1.03A | 3uj7B-3gczA:8.9 | 3uj7B-3gczA:25.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7l | ENDOGLUCANASE (Vibrioparahaemolyticus) |
PF00759(Glyco_hydro_9)PF02927(CelD_N) | 5 | GLY A 250GLY A 252ILE A 255ARG A 248ALA A 245 | None | 1.04A | 3uj7B-3h7lA:undetectable | 3uj7B-3h7lA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hnr | PROBABLEMETHYLTRANSFERASEBT9727_4108 (Bacillusthuringiensis) |
PF08241(Methyltransf_11) | 5 | GLY A 53GLY A 55ALA A 115HIS A 118LEU A 119 | None | 0.40A | 3uj7B-3hnrA:15.8 | 3uj7B-3hnrA:22.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iau | THREONINE DEAMINASE (Solanumlycopersicum) |
PF00291(PALP) | 5 | LEU A 69GLY A 324ILE A 322ILE A 339ALA A 327 | None | 1.22A | 3uj7B-3iauA:undetectable | 3uj7B-3iauA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ilw | DNA GYRASE SUBUNIT A (Mycobacteriumtuberculosis) |
PF00521(DNA_topoisoIV) | 5 | GLY A 342ILE A 189ASP A 242ALA A 243LEU A 358 | None | 0.72A | 3uj7B-3ilwA:undetectable | 3uj7B-3ilwA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o4c | DE NOVO DESIGNEDBETA-TREFOILARCHITECTURE WITHSYMMETRIC PRIMARYSTRUCTURE (syntheticconstruct) |
PF00167(FGF) | 5 | LEU A 65ILE A 111GLY A 33ILE A 25ASP A 118 | None | 1.16A | 3uj7B-3o4cA:undetectable | 3uj7B-3o4cA:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pgb | PUTATIVEUNCHARACTERIZEDPROTEIN (Aspergillusnidulans) |
PF01179(Cu_amine_oxid)PF09248(DUF1965) | 5 | ILE A 501GLY A 429GLY A 427ALA A 432LEU A 465 | TPQ A 504 ( 4.8A)NoneNoneNoneNone | 0.80A | 3uj7B-3pgbA:undetectable | 3uj7B-3pgbA:15.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q41 | GLUTAMATE [NMDA]RECEPTOR SUBUNITZETA-1 (Rattusnorvegicus) |
PF01094(ANF_receptor) | 5 | ILE A 83GLY A 30ILE A 116ASP A 81LEU A 33 | None | 0.98A | 3uj7B-3q41A:undetectable | 3uj7B-3q41A:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r2g | INOSINE5'-MONOPHOSPHATEDEHYDROGENASE (Legionellapneumophila) |
PF00478(IMPDH) | 5 | LEU A 218GLY A 298GLY A 302ILE A 214LEU A 43 | None | 1.20A | 3uj7B-3r2gA:undetectable | 3uj7B-3r2gA:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r2h | BACTERIOFERRITIN (Pseudomonasaeruginosa) |
PF00210(Ferritin) | 5 | LEU A 44ILE A 76GLY A 79ILE A 27ALA A 88 | None | 0.85A | 3uj7B-3r2hA:undetectable | 3uj7B-3r2hA:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vtx | MAMA (CandidatusMagnetobacteriumbavaricum) |
PF00515(TPR_1)PF13174(TPR_6)PF13181(TPR_8)PF13414(TPR_11) | 5 | GLY A 119ILE A 117ILE A 98ASP A 133ALA A 134 | None | 1.22A | 3uj7B-3vtxA:undetectable | 3uj7B-3vtxA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4crs | SERINE/THREONINE-PROTEIN KINASE N2 (Homo sapiens) |
PF00069(Pkinase)PF00433(Pkinase_C) | 5 | LEU A 673ILE A 937GLY A 743ASP A 791ALA A 740 | NoneNoneNoneNoneAGS A1985 (-3.9A) | 1.21A | 3uj7B-4crsA:undetectable | 3uj7B-4crsA:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dad | PUTATIVE PILUSASSEMBLY-RELATEDPROTEIN (Burkholderiapseudomallei) |
PF00072(Response_reg) | 5 | LEU A 70GLY A 34ASP A 55ALA A 7LEU A 5 | None | 1.03A | 3uj7B-4dadA:4.3 | 3uj7B-4dadA:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dq1 | THYMIDYLATE SYNTHASE (Staphylococcusaureus) |
PF00303(Thymidylat_synt) | 5 | LEU A 12ILE A 19GLY A 20ILE A 225HIS A 37 | None | 1.23A | 3uj7B-4dq1A:undetectable | 3uj7B-4dq1A:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e6y | CITRATE SYNTHASE (Vibriovulnificus) |
PF00285(Citrate_synt) | 5 | LEU A 165ILE A 118GLY A 140ILE A 253ALA A 143 | None | 1.00A | 3uj7B-4e6yA:undetectable | 3uj7B-4e6yA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4egw | MAGNESIUM TRANSPORTPROTEIN CORA (Methanocaldococcusjannaschii) |
PF01544(CorA) | 5 | ILE A 77GLY A 58ILE A 50ILE A 57LEU A 100 | None | 0.79A | 3uj7B-4egwA:undetectable | 3uj7B-4egwA:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f5x | RNA-DIRECTED RNAPOLYMERASE (Rotavirus A) |
PF02123(RdRP_4)PF12289(Rotavirus_VP1) | 5 | LEU W 465GLY W 450ILE W 447ARG W 460ALA W 590 | None | 0.67A | 3uj7B-4f5xW:undetectable | 3uj7B-4f5xW:13.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fno | PEPTIDYL-TRNAHYDROLASE (Pseudomonasaeruginosa) |
PF01195(Pept_tRNA_hydro) | 5 | LEU A 118GLY A 9GLY A 11ALA A 93HIS A 94 | None | 1.13A | 3uj7B-4fnoA:undetectable | 3uj7B-4fnoA:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ine | PROTEIN PMT-2 (Caenorhabditiselegans) |
PF08241(Methyltransf_11) | 5 | LEU A 182GLY A 232GLY A 234ARG A 298HIS A 303 | SAH A 501 (-4.0A)SAH A 501 (-3.6A)SAH A 501 (-3.6A)NoneSAH A 501 (-4.0A) | 0.57A | 3uj7B-4ineA:38.6 | 3uj7B-4ineA:23.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ine | PROTEIN PMT-2 (Caenorhabditiselegans) |
PF08241(Methyltransf_11) | 6 | LEU A 182ILE A 204GLY A 232GLY A 234ASP A 299HIS A 303 | SAH A 501 (-4.0A)SAH A 501 (-4.5A)SAH A 501 (-3.6A)SAH A 501 (-3.6A)NoneSAH A 501 (-4.0A) | 0.79A | 3uj7B-4ineA:38.6 | 3uj7B-4ineA:23.63 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4iv8 | PHOSPHOETHANOLAMINEN-METHYLTRANSFERASE,PUTATIVE (Plasmodiumknowlesi) |
PF08241(Methyltransf_11) | 5 | GLY A 61GLY A 63CYH A 85ARG A 125ASP A 126 | SAM A 301 (-3.5A)SAM A 301 ( 3.9A)BME A 302 (-1.9A)NoneNone | 0.80A | 3uj7B-4iv8A:35.5 | 3uj7B-4iv8A:59.01 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4iv8 | PHOSPHOETHANOLAMINEN-METHYLTRANSFERASE,PUTATIVE (Plasmodiumknowlesi) |
PF08241(Methyltransf_11) | 8 | GLY A 61GLY A 63ILE A 84ARG A 125ASP A 126ALA A 127HIS A 130LEU A 131 | SAM A 301 (-3.5A)SAM A 301 ( 3.9A)SAM A 301 (-3.8A)NoneNoneSAM A 301 (-3.4A)SAM A 301 (-3.9A)None | 0.36A | 3uj7B-4iv8A:35.5 | 3uj7B-4iv8A:59.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jga | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 2 (Rickettsiarickettsii) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | LEU A 336ILE A 307ILE A 312ASP A 304ALA A 301 | None | 1.03A | 3uj7B-4jgaA:undetectable | 3uj7B-4jgaA:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kri | PHOSPHOLETHANOLAMINEN-METHYLTRANSFERASE2 (Haemonchuscontortus) |
PF08241(Methyltransf_11) | 5 | LEU A 178GLY A 228GLY A 230ARG A 294HIS A 299 | SAH A 701 ( 4.2A)SAH A 701 (-3.5A)SAH A 701 (-3.5A)NoneSAH A 701 (-4.2A) | 0.54A | 3uj7B-4kriA:38.7 | 3uj7B-4kriA:23.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kri | PHOSPHOLETHANOLAMINEN-METHYLTRANSFERASE2 (Haemonchuscontortus) |
PF08241(Methyltransf_11) | 6 | LEU A 178ILE A 200GLY A 228GLY A 230ASP A 295HIS A 299 | SAH A 701 ( 4.2A)SAH A 701 ( 4.5A)SAH A 701 (-3.5A)SAH A 701 (-3.5A)NoneSAH A 701 (-4.2A) | 0.66A | 3uj7B-4kriA:38.7 | 3uj7B-4kriA:23.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kri | PHOSPHOLETHANOLAMINEN-METHYLTRANSFERASE2 (Haemonchuscontortus) |
PF08241(Methyltransf_11) | 5 | LEU A 314GLY A 361ILE A 310ASP A 364ALA A 427 | None | 0.86A | 3uj7B-4kriA:38.7 | 3uj7B-4kriA:23.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kws | D-MANNONATEDEHYDRATASE (Chromohalobactersalexigens) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | LEU A 3ILE A 24GLY A 32ILE A 98ASP A 7 | None | 1.08A | 3uj7B-4kwsA:undetectable | 3uj7B-4kwsA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lmp | ALANINEDEHYDROGENASE (Mycobacteriumtuberculosis) |
PF01262(AlaDh_PNT_C)PF05222(AlaDh_PNT_N) | 5 | GLY A 180GLY A 138ILE A 267ARG A 185ALA A 184 | None | 1.22A | 3uj7B-4lmpA:5.3 | 3uj7B-4lmpA:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lz6 | BH2163 PROTEIN (Bacillushalodurans) |
PF01554(MatE) | 5 | LEU A 101ILE A 81GLY A 74GLY A 77ILE A 104 | None | 1.07A | 3uj7B-4lz6A:undetectable | 3uj7B-4lz6A:17.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4mwz | PHOSPHOETHANOLAMINEN-METHYLTRANSFERASE,PUTATIVE (Plasmodiumvivax) |
PF13649(Methyltransf_25) | 6 | ILE A 33GLY A 60GLY A 62CYH A 84ARG A 124ASP A 125 | SAM A 301 (-4.3A)SAM A 301 (-3.7A)SAM A 301 ( 3.8A)BME A 303 (-1.9A)NoneNone | 0.74A | 3uj7B-4mwzA:41.5 | 3uj7B-4mwzA:63.53 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4mwz | PHOSPHOETHANOLAMINEN-METHYLTRANSFERASE,PUTATIVE (Plasmodiumvivax) |
PF13649(Methyltransf_25) | 8 | ILE A 33GLY A 60GLY A 62ILE A 83ARG A 124ASP A 125HIS A 129LEU A 130 | SAM A 301 (-4.3A)SAM A 301 (-3.7A)SAM A 301 ( 3.8A)SAM A 301 (-3.7A)NoneNoneSAM A 301 (-3.9A)None | 0.18A | 3uj7B-4mwzA:41.5 | 3uj7B-4mwzA:63.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oyd | APOPTOSIS REGULATORBHRF1 (Humangammaherpesvirus4) |
PF00452(Bcl-2) | 5 | LEU A 54ILE A 154GLY A 99ILE A 57ALA A 101 | None | 1.18A | 3uj7B-4oydA:undetectable | 3uj7B-4oydA:18.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p9n | CARBOXYLESTERASE (Sulfolobusshibatae) |
PF07859(Abhydrolase_3) | 5 | LEU A 198ILE A 84ILE A 203ILE A 19ALA A 152 | None | 1.00A | 3uj7B-4p9nA:4.0 | 3uj7B-4p9nA:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4peq | RIBONUCLEASE/ANGIOGENIN INHIBITOR 1 (Bos taurus) |
PF13516(LRR_6) | 5 | LEU B 271GLY B 238CYH B 243ARG B 233ASP B 262 | None | 1.21A | 3uj7B-4peqB:undetectable | 3uj7B-4peqB:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pvv | ADENOSINE KINASE (Mycobacteriumtuberculosis) |
PF00294(PfkB) | 5 | ILE A 127GLY A 7GLY A 68ILE A 143ASP A 148 | None | 1.22A | 3uj7B-4pvvA:2.8 | 3uj7B-4pvvA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qtu | PUTATIVEMETHYLTRANSFERASEBUD23 (Saccharomycescerevisiae) |
PF08241(Methyltransf_11) | 5 | GLY B 55GLY B 57ILE B 78ALA B 119LEU B 123 | SAM B 301 (-3.7A)SAM B 301 (-3.3A)SAM B 301 (-3.7A)SAM B 301 (-3.5A)CSO B 124 ( 4.4A) | 0.53A | 3uj7B-4qtuB:19.1 | 3uj7B-4qtuB:22.96 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4r6w | PHOSPHOETHANOLAMINEN-METHYLTRANSFERASE (Plasmodiumfalciparum) |
PF13649(Methyltransf_25) | 10 | LEU A 14ILE A 36GLY A 63GLY A 65ILE A 86CYH A 87ARG A 127ALA A 129HIS A 132LEU A 133 | NoneSAH A 302 ( 3.9A)SAH A 302 (-3.7A)SAH A 302 (-3.6A)SAH A 302 (-3.7A)SAH A 302 (-3.4A)NoneSAH A 302 (-3.3A)SAH A 302 (-4.3A)None | 0.28A | 3uj7B-4r6wA:46.2 | 3uj7B-4r6wA:99.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4r6w | PHOSPHOETHANOLAMINEN-METHYLTRANSFERASE (Plasmodiumfalciparum) |
PF13649(Methyltransf_25) | 8 | LEU A 14ILE A 36GLY A 65ILE A 86CYH A 87ILE A 90ARG A 127HIS A 132 | NoneSAH A 302 ( 3.9A)SAH A 302 (-3.6A)SAH A 302 (-3.7A)SAH A 302 (-3.4A)NoneNoneSAH A 302 (-4.3A) | 0.49A | 3uj7B-4r6wA:46.2 | 3uj7B-4r6wA:99.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r7u | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Vibrio cholerae) |
PF00275(EPSP_synthase) | 5 | LEU A 199GLY A 223GLY A 225ALA A 36LEU A 176 | None | 1.20A | 3uj7B-4r7uA:undetectable | 3uj7B-4r7uA:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rsl | FRUCTOSYL PEPTIDEOXIDASE (Penicilliumterrenum) |
PF01266(DAO) | 5 | GLY A 266GLY A 263CYH A 97ALA A 328LEU A 333 | None | 1.11A | 3uj7B-4rslA:2.5 | 3uj7B-4rslA:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4woq | N-ACETYLNEURAMINATELYASE (Clostridioidesdifficile) |
PF00701(DHDPS) | 5 | LEU A 22ILE A 32GLY A 36ILE A 76LEU A 269 | None | 1.22A | 3uj7B-4woqA:undetectable | 3uj7B-4woqA:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xhp | PARM HYBRID FUSIONPROTEIN (Bacillusthuringiensis) |
no annotation | 5 | LEU A 384GLY A 377GLY A 373ASP A 350ALA A 348 | NoneNoneADP A 901 (-4.2A)NoneNone | 0.98A | 3uj7B-4xhpA:undetectable | 3uj7B-4xhpA:16.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yxm | DNA INTEGRITYSCANNING PROTEINDISA (Thermotogamaritima) |
PF00633(HHH)PF02457(DisA_N)PF10635(DisA-linker) | 5 | LEU A 80ILE A 18ILE A 78ILE A 124ALA A 27 | None | 0.95A | 3uj7B-4yxmA:undetectable | 3uj7B-4yxmA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zlv | ORNITHINEAMINOTRANSFERASE,MITOCHONDRIAL,PUTATIVE (Toxoplasmagondii) |
PF00202(Aminotran_3) | 5 | LEU A 132GLY A 285GLY A 136ILE A 295LEU A 331 | NoneNonePLP A 501 (-3.1A)NoneNone | 0.93A | 3uj7B-4zlvA:undetectable | 3uj7B-4zlvA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zm4 | AMINOTRANSFERASE (Streptomycespactum) |
PF00202(Aminotran_3) | 5 | GLY A 289GLY A 110ARG A 291ALA A 293LEU A 130 | None | 1.24A | 3uj7B-4zm4A:2.3 | 3uj7B-4zm4A:18.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b3j | NMDA GLUTAMATERECEPTOR SUBUNIT (Xenopus laevis) |
PF01094(ANF_receptor) | 5 | ILE A 83GLY A 30ILE A 116ASP A 81LEU A 33 | None | 1.07A | 3uj7B-5b3jA:undetectable | 3uj7B-5b3jA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b3j | NMDA GLUTAMATERECEPTOR SUBUNIT (Xenopus laevis) |
PF01094(ANF_receptor) | 5 | ILE A 374GLY A 271GLY A 289ILE A 241ILE A 288 | None | 0.95A | 3uj7B-5b3jA:undetectable | 3uj7B-5b3jA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dgq | PUTATIVEENDOGLUCANASE-RELATED PROTEIN (Photobacteriumprofundum) |
PF00759(Glyco_hydro_9) | 5 | GLY A 249GLY A 251ILE A 254ARG A 247ALA A 244 | None | 0.96A | 3uj7B-5dgqA:undetectable | 3uj7B-5dgqA:18.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e1b | N-TERMINALXAA-PRO-LYSN-METHYLTRANSFERASE1 (Homo sapiens) |
PF05891(Methyltransf_PK) | 5 | GLY A 69GLY A 71ILE A 92HIS A 140LEU A 141 | SAH A 301 (-3.9A)SAH A 301 (-3.1A)SAH A 301 (-3.9A)SAH A 301 (-3.8A)None | 0.61A | 3uj7B-5e1bA:18.4 | 3uj7B-5e1bA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e9q | GENOME POLYPROTEIN (Dengue virus) |
PF01728(FtsJ) | 5 | GLY A 148ILE A 179CYH A 145ILE A 147LEU A 193 | NoneNoneNoneSAM A 301 ( 4.2A)None | 1.00A | 3uj7B-5e9qA:8.3 | 3uj7B-5e9qA:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gt5 | PECTATE LYASE (Paenibacillussp. 0602) |
no annotation | 5 | ILE A 273GLY A 175GLY A 246ILE A 154ALA A 172 | None | 0.92A | 3uj7B-5gt5A:undetectable | 3uj7B-5gt5A:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hdt | SISTER CHROMATIDCOHESION PROTEINPDS5 HOMOLOG B (Homo sapiens) |
no annotation | 5 | LEU A 604ILE A 449ILE A 532ASP A 538ALA A 542 | None | 1.22A | 3uj7B-5hdtA:undetectable | 3uj7B-5hdtA:12.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hei | NFRA2 (Bacillusmegaterium) |
PF00881(Nitroreductase) | 5 | LEU A 60GLY A 135ILE A 78ILE A 134LEU A 150 | NoneFMN A 301 (-3.5A)NoneFMN A 301 ( 4.1A)None | 1.02A | 3uj7B-5heiA:undetectable | 3uj7B-5heiA:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ikm | NS5 METHYLTRANSFERASE (Dengue virus) |
PF01728(FtsJ) | 5 | GLY A 148ILE A 179CYH A 145ILE A 147LEU A 193 | NoneNoneNoneSAM A 311 ( 4.3A)None | 0.98A | 3uj7B-5ikmA:8.5 | 3uj7B-5ikmA:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jjr | GENOME POLYPROTEIN (Dengue virus) |
PF00972(Flavi_NS5)PF01728(FtsJ) | 5 | GLY A 148ILE A 179CYH A 145ILE A 147LEU A 193 | NoneNoneNoneSAH A1003 ( 4.3A)None | 0.96A | 3uj7B-5jjrA:8.4 | 3uj7B-5jjrA:15.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ltm | PHENYLALANINEAMMONIA LYASE (Anabaena) |
no annotation | 5 | LEU B 181ILE B 139ILE B 177ALA B 129LEU B 151 | None | 1.17A | 3uj7B-5ltmB:undetectable | 3uj7B-5ltmB:18.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n28 | METHYL-COENZYME MREDUCTASE SUBUNITALPHA (Methanotorrisformicicus) |
PF02249(MCR_alpha)PF02745(MCR_alpha_N) | 5 | GLY A 428GLY A 425ILE A 493ALA A 376LEU A 435 | TRX A 429 ( 2.4A)NoneNoneNoneNone | 1.15A | 3uj7B-5n28A:undetectable | 3uj7B-5n28A:18.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nit | GLUCOSE OXIDASE (Aspergillusniger) |
no annotation | 5 | GLY A 304GLY A 302ILE A 308ILE A 314LEU A 324 | None | 0.96A | 3uj7B-5nitA:undetectable | 3uj7B-5nitA:17.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nju | GENOME POLYPROTEIN (Zika virus) |
no annotation | 5 | GLY A 148ILE A 181CYH A 145ILE A 147LEU A 195 | NoneNoneNoneSAH A1001 (-4.2A)None | 1.06A | 3uj7B-5njuA:8.8 | 3uj7B-5njuA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nrm | DOCCEL5: TYPE IDOCKERIN REPEATDOMAIN FROM A.CELLULOLYTICUSFAMILY 5ENDOGLUCANASEWP_010249057 S51I,L52N MUTANT (Acetivibriocellulolyticus) |
no annotation | 5 | GLY B 10ILE B 14ASP B 37ALA B 41LEU B 44 | None | 0.81A | 3uj7B-5nrmB:undetectable | 3uj7B-5nrmB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tw7 | GMP SYNTHASE[GLUTAMINE-HYDROLYZING] (Neisseriagonorrhoeae) |
PF00117(GATase)PF00958(GMP_synt_C)PF02540(NAD_synthase) | 5 | LEU A 183ILE A 51GLY A 167GLY A 79ILE A 80 | None | 1.24A | 3uj7B-5tw7A:2.3 | 3uj7B-5tw7A:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u2p | SUGAR ABCTRANSPORTERSUBSTRATE-BINDINGPROTEIN (Treponemapallidum) |
PF01547(SBP_bac_1) | 5 | LEU A 352GLY A 310CYH A 143ILE A 127LEU A 279 | NoneEDO A 504 ( 3.9A)NoneNoneNone | 1.05A | 3uj7B-5u2pA:undetectable | 3uj7B-5u2pA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wp4 | PHOSPHOETHANOLAMINEN-METHYLTRANSFERASE1 (Arabidopsisthaliana) |
no annotation | 6 | LEU A 241GLY A 290GLY A 292ARG A 355ASP A 356HIS A 360 | SAH A 703 (-4.0A)SAH A 703 (-4.0A)SAH A 703 ( 3.7A)None PC A 702 ( 4.6A)SAH A 703 (-4.0A) | 0.36A | 3uj7B-5wp4A:40.5 | 3uj7B-5wp4A:23.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wp5 | PHOSPHOMETHYLETHANOLAMINEN-METHYLTRANSFERASE2 (Arabidopsisthaliana) |
no annotation | 5 | GLY A 290GLY A 292ARG A 355ASP A 356HIS A 360 | SAH A 501 (-3.8A)SAH A 501 (-3.6A)NoneNoneSAH A 501 (-4.0A) | 0.18A | 3uj7B-5wp5A:33.4 | 3uj7B-5wp5A:23.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wug | BETA-GLUCOSIDASE (Paenibacillusbarengoltzii) |
no annotation | 5 | LEU A 524GLY A 553GLY A 555ILE A 532LEU A 507 | None | 1.02A | 3uj7B-5wugA:undetectable | 3uj7B-5wugA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x3j | GLYCOSIDE HYDROLASEFAMILY 31 (Kribbellaflavida) |
no annotation | 5 | LEU A 718GLY A 689CYH A 710ILE A 684LEU A 612 | None | 1.07A | 3uj7B-5x3jA:undetectable | 3uj7B-5x3jA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ykd | D-HYDANTOINASE/DIHYDROPYRIMIDINASE (Pseudomonasaeruginosa) |
no annotation | 5 | LEU A 51ILE A 5ILE A 31ASP A 390ALA A 391 | None | 0.89A | 3uj7B-5ykdA:undetectable | 3uj7B-5ykdA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bj9 | ACETYL-COAACETYLTRANSFERASE A (Ascaris suum) |
no annotation | 5 | LEU A 300GLY A 384GLY A 279ILE A 386ALA A 374 | None | 1.17A | 3uj7B-6bj9A:undetectable | 3uj7B-6bj9A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gdt | - (-) |
no annotation | 5 | GLY A 250GLY A 252ILE A 255ARG A 248ALA A 245 | None | 0.95A | 3uj7B-6gdtA:undetectable | 3uj7B-6gdtA:undetectable |