SIMILAR PATTERNS OF AMINO ACIDS FOR 3UJ7_A_SAMA301_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a6d | THERMOSOME (BETASUBUNIT) (Thermoplasmaacidophilum) |
PF00118(Cpn60_TCP1) | 5 | LEU B 105GLY B 125ILE B 511ARG B 430ALA B 434 | None | 1.12A | 3uj7A-1a6dB:0.0 | 3uj7A-1a6dB:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c9k | ADENOSYLCOBINAMIDEKINASE (Salmonellaenterica) |
PF02283(CobU) | 5 | LEU A 161ILE A 115ILE A 111ARG A 151ALA A 154 | None | 1.21A | 3uj7A-1c9kA:0.0 | 3uj7A-1c9kA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dk5 | ANNEXIN 24(CA32) (Capsicum annuum) |
PF00191(Annexin) | 5 | LEU A 297TYR A 289ILE A 301ASP A 258ALA A 259 | None | 1.24A | 3uj7A-1dk5A:0.0 | 3uj7A-1dk5A:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qfc | PROTEIN (PURPLE ACIDPHOSPHATASE) (Rattusnorvegicus) |
PF00149(Metallophos) | 5 | LEU A 225TYR A 287ILE A 285ILE A 35ALA A 11 | None | 1.35A | 3uj7A-1qfcA:0.4 | 3uj7A-1qfcA:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rgv | FERREDOXIN (Thaueraaromatica) |
PF00037(Fer4) | 5 | TYR A 30ILE A 23CYH A 8ILE A 4ALA A 13 | SF4 A 101 ( 3.8A)NoneSF4 A 101 (-2.4A)SF4 A 101 ( 4.1A)SF4 A 101 ( 4.1A) | 0.89A | 3uj7A-1rgvA:undetectable | 3uj7A-1rgvA:15.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vl0 | DTDP-4-DEHYDRORHAMNOSE REDUCTASE, RFBDORTHOLOG (Clostridiumacetobutylicum) |
PF04321(RmlD_sub_bind) | 5 | LEU A 12ILE A 3ILE A 99CYH A 58ILE A 145 | NAI A 300 (-4.5A)NoneNAI A 300 (-4.2A)NoneNone | 1.13A | 3uj7A-1vl0A:0.9 | 3uj7A-1vl0A:22.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vlu | GAMMA-GLUTAMYLPHOSPHATE REDUCTASE (Saccharomycescerevisiae) |
PF00171(Aldedh) | 5 | ILE A 246ILE A 266ILE A 232ASP A 239ALA A 238 | None | 1.18A | 3uj7A-1vluA:0.0 | 3uj7A-1vluA:19.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ydm | HYPOTHETICAL PROTEINYQGN (Bacillussubtilis) |
PF01812(5-FTHF_cyc-lig) | 5 | LEU A 35ILE A 120ILE A 182ILE A 183ARG A 132 | NoneNoneNoneNoneSO4 A 301 (-2.6A) | 1.03A | 3uj7A-1ydmA:2.3 | 3uj7A-1ydmA:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z9a | NAD(P)H-DEPENDENTD-XYLOSE REDUCTASE ([Candida]tenuis) |
PF00248(Aldo_ket_red) | 5 | ILE A 147ILE A 166ILE A 113ARG A 181ALA A 183 | None | 0.92A | 3uj7A-1z9aA:0.4 | 3uj7A-1z9aA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aaz | THYMIDYLATE SYNTHASE (Cryptococcusneoformans) |
PF00303(Thymidylat_synt) | 5 | LEU A 251ILE A 27ARG A 37ASP A 255ALA A 256 | None | 1.35A | 3uj7A-2aazA:undetectable | 3uj7A-2aazA:20.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f9i | ACETYL-COENZYME ACARBOXYLASE CARBOXYLTRANSFERASE SUBUNITBETA (Staphylococcusaureus) |
PF01039(Carboxyl_trans) | 5 | LEU B 221TYR B 200ILE B 70ILE B 160ILE B 279 | None | 1.03A | 3uj7A-2f9iB:undetectable | 3uj7A-2f9iB:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f9i | ACETYL-COENZYME ACARBOXYLASE CARBOXYLTRANSFERASE SUBUNITBETA (Staphylococcusaureus) |
PF01039(Carboxyl_trans) | 5 | LEU B 221TYR B 200ILE B 70ILE B 219ILE B 160 | None | 1.11A | 3uj7A-2f9iB:undetectable | 3uj7A-2f9iB:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ggq | 401AA LONGHYPOTHETICALGLUCOSE-1-PHOSPHATETHYMIDYLYLTRANSFERASE (Sulfurisphaeratokodaii) |
PF00132(Hexapep)PF00483(NTP_transferase) | 5 | LEU A 163ILE A 144GLY A 159ILE A 95ILE A 96 | None | 0.99A | 3uj7A-2ggqA:undetectable | 3uj7A-2ggqA:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hk3 | DIPHOSPHOMEVALONATEDECARBOXYLASE (Staphylococcusaureus) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 5 | LEU A 167ILE A 34ILE A 236ASP A 226ALA A 223 | None | 1.38A | 3uj7A-2hk3A:undetectable | 3uj7A-2hk3A:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ixd | LMBE-RELATED PROTEIN (Bacillus cereus) |
PF02585(PIG-L) | 5 | LEU A 39ILE A 36ILE A 89ILE A 124ALA A 103 | None | 1.26A | 3uj7A-2ixdA:undetectable | 3uj7A-2ixdA:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rfg | DIHYDRODIPICOLINATESYNTHASE (Hahellachejuensis) |
PF00701(DHDPS) | 5 | ILE A 202GLY A 158ILE A 129ILE A 73ASP A 161 | None | 0.85A | 3uj7A-2rfgA:undetectable | 3uj7A-2rfgA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2var | FRUCTOKINASE (Sulfolobussolfataricus) |
PF00294(PfkB) | 5 | LEU A 11ILE A 79GLY A 57ILE A 65ALA A 112 | KDG A1313 ( 4.7A)NoneNoneNoneNone | 0.97A | 3uj7A-2varA:undetectable | 3uj7A-2varA:25.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vk9 | ALPHA-TOXIN (Clostridiumnovyi) |
PF12918(TcdB_N)PF12919(TcdA_TcdB) | 5 | LEU A 295ILE A 344ILE A 314ILE A 353HIS A 351 | None | 1.03A | 3uj7A-2vk9A:undetectable | 3uj7A-2vk9A:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xok | ATP SYNTHASE SUBUNITGAMMA, MITOCHONDRIAL (Saccharomycescerevisiae) |
PF00231(ATP-synt) | 5 | LEU G 219ILE G 133ARG G 30ASP G 136ALA G 137 | None | 1.31A | 3uj7A-2xokG:undetectable | 3uj7A-2xokG:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z1u | HYDROGENASEEXPRESSION/FORMATIONPROTEIN HYPE (Desulfovibriovulgaris) |
PF00586(AIRS)PF02769(AIRS_C) | 5 | LEU A 285GLY A 301ILE A 168ASP A 164ALA A 165 | None | 1.38A | 3uj7A-2z1uA:undetectable | 3uj7A-2z1uA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zau | SELENIDE, WATERDIKINASE (Aquifexaeolicus) |
PF00586(AIRS)PF02769(AIRS_C) | 5 | LEU A 81GLY A 73ARG A 115ASP A 119ALA A 117 | None | 1.12A | 3uj7A-2zauA:undetectable | 3uj7A-2zauA:24.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zcv | UNCHARACTERIZEDOXIDOREDUCTASE YTFG (Escherichiacoli) |
PF05368(NmrA) | 5 | LEU A 71TYR A 101ILE A 88ALA A 81HIS A 84 | None | 1.08A | 3uj7A-2zcvA:5.2 | 3uj7A-2zcvA:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b1f | PUTATIVE PREPHENATEDEHYDROGENASE (Streptococcusmutans) |
PF02153(PDH) | 5 | ILE A 250ILE A 238ILE A 194ASP A 248ALA A 245 | None | 1.29A | 3uj7A-3b1fA:4.9 | 3uj7A-3b1fA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bf0 | PROTEASE 4 (Escherichiacoli) |
PF01343(Peptidase_S49) | 5 | LEU A 138ILE A 63ILE A 100ILE A 113ASP A 119 | None | 0.97A | 3uj7A-3bf0A:undetectable | 3uj7A-3bf0A:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bg2 | DGTPTRIPHOSPHOHYDROLASE (Leeuwenhoekiellablandensis) |
PF01966(HD) | 5 | ILE A 315ILE A 260CYH A 256ILE A 255ALA A 308 | None | 0.99A | 3uj7A-3bg2A:undetectable | 3uj7A-3bg2A:23.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dni | DEOXYRIBONUCLEASE I (Bos taurus) |
PF03372(Exo_endo_phos) | 5 | LEU A 81ILE A 25GLY A 12ILE A 8ALA A 47 | None | 0.85A | 3uj7A-3dniA:undetectable | 3uj7A-3dniA:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e4p | C4-DICARBOXYLATETRANSPORT SENSORPROTEIN DCTB (Sinorhizobiummeliloti) |
no annotation | 5 | ILE A 194ILE A 180ILE A 126ASP A 161ALA A 158 | None | 0.95A | 3uj7A-3e4pA:undetectable | 3uj7A-3e4pA:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eu8 | PUTATIVEGLUCOAMYLASE (Bacteroidesfragilis) |
PF10091(Glycoamylase)PF11329(DUF3131) | 5 | LEU A 159ILE A 411GLY A 91ILE A 95ALA A 65 | NoneNoneEDO A 474 (-3.3A)NoneEDO A 474 (-3.6A) | 1.37A | 3uj7A-3eu8A:undetectable | 3uj7A-3eu8A:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ga2 | ENDONUCLEASE V (Bacillussubtilis) |
PF04493(Endonuclease_5) | 5 | ILE A 143GLY A 44ILE A 65ASP A 223ALA A 222 | None | 1.19A | 3uj7A-3ga2A:undetectable | 3uj7A-3ga2A:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hmj | FATTY ACID SYNTHASESUBUNIT ALPHA (Saccharomycescerevisiae) |
PF00109(ketoacyl-synt)PF01648(ACPS)PF02801(Ketoacyl-synt_C) | 5 | LEU A 916GLY A 866ILE A 823ASP A 925ALA A 924 | None | 1.22A | 3uj7A-3hmjA:undetectable | 3uj7A-3hmjA:8.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iau | THREONINE DEAMINASE (Solanumlycopersicum) |
PF00291(PALP) | 5 | LEU A 69GLY A 324ILE A 322ILE A 339ALA A 327 | None | 1.21A | 3uj7A-3iauA:2.3 | 3uj7A-3iauA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k30 | HISTAMINEDEHYDROGENASE (Pimelobactersimplex) |
PF00724(Oxidored_FMN)PF07992(Pyr_redox_2) | 5 | ILE A 246GLY A 254CYH A 229ILE A 231ARG A 251 | None | 1.36A | 3uj7A-3k30A:undetectable | 3uj7A-3k30A:16.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nav | TRYPTOPHAN SYNTHASEALPHA CHAIN (Vibrio cholerae) |
PF00290(Trp_syntA) | 5 | ILE A 241GLY A 26ILE A 36ILE A 80ALA A 71 | None | 1.20A | 3uj7A-3navA:undetectable | 3uj7A-3navA:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nnd | POSSIBLE SUBSTRATEBINDING PROTEIN OFABC TRANSPORTERSYSTEM (Rhodopseudomonaspalustris) |
no annotation | 5 | LEU B 75ILE B 109ILE B 20ASP B 85ALA B 84 | None | 1.38A | 3uj7A-3nndB:undetectable | 3uj7A-3nndB:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nnm | CURA (Lyngbyamajuscula) |
PF05721(PhyH) | 5 | LEU A 112ILE A 61ILE A 58ARG A 259HIS A 115 | FMT A 500 ( 4.8A)NoneNoneNoneNone | 1.36A | 3uj7A-3nnmA:undetectable | 3uj7A-3nnmA:22.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nz4 | PHENYLALANINEAMMONIA-LYASE (Taxuscanadensis) |
PF00221(Lyase_aromatic) | 5 | LEU A 250ILE A 18GLY A 663ILE A 660ARG A 46 | None | 0.91A | 3uj7A-3nz4A:undetectable | 3uj7A-3nz4A:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oa2 | WBPB (Pseudomonasaeruginosa) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 5 | LEU A 28ILE A 7ILE A 41ILE A 40ALA A 14 | None | 1.28A | 3uj7A-3oa2A:undetectable | 3uj7A-3oa2A:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pea | ENOYL-COAHYDRATASE/ISOMERASEFAMILY PROTEIN (Bacillusanthracis) |
PF00378(ECH_1) | 5 | LEU A 191ILE A 13ILE A 99ILE A 47ALA A 16 | None | 1.15A | 3uj7A-3peaA:undetectable | 3uj7A-3peaA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r2h | BACTERIOFERRITIN (Pseudomonasaeruginosa) |
PF00210(Ferritin) | 5 | LEU A 44ILE A 76GLY A 79ILE A 27ALA A 88 | None | 0.82A | 3uj7A-3r2hA:undetectable | 3uj7A-3r2hA:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ru8 | EPITOPE SCAFFOLD2BODX43 (Thermobifidafusca;Humanimmunodeficiencyvirus;syntheticconstruct) |
PF01341(Glyco_hydro_6) | 5 | LEU X 244ILE X 105ILE X 141ARG X 100ALA X 102 | None | 1.18A | 3uj7A-3ru8X:undetectable | 3uj7A-3ru8X:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t1i | DOUBLE-STRAND BREAKREPAIR PROTEINMRE11A (Homo sapiens) |
PF00149(Metallophos)PF04152(Mre11_DNA_bind) | 5 | LEU A 213ILE A 164ILE A 242ILE A 263ASP A 235 | None | 1.23A | 3uj7A-3t1iA:undetectable | 3uj7A-3t1iA:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vtx | MAMA (CandidatusMagnetobacteriumbavaricum) |
PF00515(TPR_1)PF13174(TPR_6)PF13181(TPR_8)PF13414(TPR_11) | 5 | GLY A 119ILE A 117ILE A 98ASP A 133ALA A 134 | None | 1.21A | 3uj7A-3vtxA:undetectable | 3uj7A-3vtxA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wxy | PUTATIVEUNCHARACTERIZEDPROTEIN CSYB (Aspergillusoryzae) |
PF00195(Chal_sti_synt_N)PF02797(Chal_sti_synt_C) | 5 | LEU A 317ILE A 60ILE A 349ASP A 340ALA A 337 | None | 0.96A | 3uj7A-3wxyA:undetectable | 3uj7A-3wxyA:18.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wyw | GLUTATHIONES-TRANSFERASE (Nilaparvatalugens) |
PF00043(GST_C)PF13417(GST_N_3) | 5 | LEU A 175TYR A 178ILE A 165ASP A 134ALA A 135 | None | 1.17A | 3uj7A-3wywA:undetectable | 3uj7A-3wywA:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4atq | 4-AMINOBUTYRATETRANSAMINASE (Paenarthrobacteraurescens) |
PF00202(Aminotran_3) | 5 | LEU A 69ILE A 389ILE A 442ARG A 363ALA A 358 | None | 1.36A | 3uj7A-4atqA:undetectable | 3uj7A-4atqA:16.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4awn | DEOXYRIBONUCLEASE-1 (Homo sapiens) |
PF03372(Exo_endo_phos) | 5 | LEU A 81ILE A 25GLY A 12ILE A 8ALA A 47 | None | 0.81A | 3uj7A-4awnA:undetectable | 3uj7A-4awnA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e6y | CITRATE SYNTHASE (Vibriovulnificus) |
PF00285(Citrate_synt) | 5 | LEU A 165ILE A 118GLY A 140ILE A 253ALA A 143 | None | 1.01A | 3uj7A-4e6yA:undetectable | 3uj7A-4e6yA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f0s | 5-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE DEAMINASE (Chromobacteriumviolaceum) |
PF01979(Amidohydro_1) | 5 | LEU A 355GLY A 305ILE A 67ILE A 127ALA A 276 | None | 1.11A | 3uj7A-4f0sA:undetectable | 3uj7A-4f0sA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g0o | PROTEIN ARGONAUTE 5 (Arabidopsisthaliana) |
PF02171(Piwi) | 5 | LEU A 639ILE A 622ILE A 663CYH A 657ILE A 656 | None | 1.30A | 3uj7A-4g0oA:undetectable | 3uj7A-4g0oA:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g8d | ALPHA/BETA HYDROLASEFOLD PROTEIN (Ochrobactrumsp. T63) |
PF00561(Abhydrolase_1) | 5 | ILE A 176GLY A 32ILE A 39ILE A 107ARG A 185 | None | 1.28A | 3uj7A-4g8dA:undetectable | 3uj7A-4g8dA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gfh | DNA TOPOISOMERASE 2 (Saccharomycescerevisiae) |
PF00204(DNA_gyraseB)PF00521(DNA_topoisoIV)PF01751(Toprim)PF02518(HATPase_c)PF16898(TOPRIM_C) | 5 | LEU A 542ILE A 672GLY A 536ILE A 638ILE A 534 | None | 1.37A | 3uj7A-4gfhA:undetectable | 3uj7A-4gfhA:13.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gx8 | DNA POLYMERASE IIISUBUNIT EPSILON,DNAPOLYMERASE IIISUBUNIT ALPHA (Escherichiacoli) |
PF02811(PHP) | 5 | TYR A 60ILE A 264ILE A 63ASP A 254ALA A 257 | None | 1.27A | 3uj7A-4gx8A:undetectable | 3uj7A-4gx8A:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h0u | THYMIDYLATE SYNTHASE (Corynebacteriumglutamicum) |
PF00303(Thymidylat_synt) | 5 | LEU A 11TYR A 7ILE A 181ILE A 37ALA A 171 | NoneNoneNoneNoneUMP A 301 ( 4.9A) | 1.09A | 3uj7A-4h0uA:undetectable | 3uj7A-4h0uA:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ine | PROTEIN PMT-2 (Caenorhabditiselegans) |
PF08241(Methyltransf_11) | 5 | LEU A 182TYR A 187GLY A 232ARG A 298HIS A 303 | SAH A 501 (-4.0A)SAH A 501 ( 4.1A)SAH A 501 (-3.6A)NoneSAH A 501 (-4.0A) | 0.64A | 3uj7A-4ineA:38.4 | 3uj7A-4ineA:23.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ine | PROTEIN PMT-2 (Caenorhabditiselegans) |
PF08241(Methyltransf_11) | 5 | LEU A 182TYR A 187GLY A 232ILE A 253ARG A 298 | SAH A 501 (-4.0A)SAH A 501 ( 4.1A)SAH A 501 (-3.6A)NoneNone | 1.16A | 3uj7A-4ineA:38.4 | 3uj7A-4ineA:23.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ine | PROTEIN PMT-2 (Caenorhabditiselegans) |
PF08241(Methyltransf_11) | 5 | LEU A 182TYR A 187GLY A 232ILE A 253ASP A 299 | SAH A 501 (-4.0A)SAH A 501 ( 4.1A)SAH A 501 (-3.6A)NoneNone | 1.20A | 3uj7A-4ineA:38.4 | 3uj7A-4ineA:23.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ine | PROTEIN PMT-2 (Caenorhabditiselegans) |
PF08241(Methyltransf_11) | 6 | LEU A 182TYR A 187ILE A 204GLY A 232ASP A 299HIS A 303 | SAH A 501 (-4.0A)SAH A 501 ( 4.1A)SAH A 501 (-4.5A)SAH A 501 (-3.6A)NoneSAH A 501 (-4.0A) | 0.74A | 3uj7A-4ineA:38.4 | 3uj7A-4ineA:23.63 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4iv8 | PHOSPHOETHANOLAMINEN-METHYLTRANSFERASE,PUTATIVE (Plasmodiumknowlesi) |
PF08241(Methyltransf_11) | 7 | GLY A 61ILE A 84ILE A 109ARG A 125ASP A 126ALA A 127HIS A 130 | SAM A 301 (-3.5A)SAM A 301 (-3.8A)SAM A 301 (-4.1A)NoneNoneSAM A 301 (-3.4A)SAM A 301 (-3.9A) | 0.34A | 3uj7A-4iv8A:35.3 | 3uj7A-4iv8A:59.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jga | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 2 (Rickettsiarickettsii) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | LEU A 336ILE A 307ILE A 312ASP A 304ALA A 301 | None | 1.02A | 3uj7A-4jgaA:undetectable | 3uj7A-4jgaA:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kri | PHOSPHOLETHANOLAMINEN-METHYLTRANSFERASE2 (Haemonchuscontortus) |
PF08241(Methyltransf_11) | 5 | LEU A 178TYR A 183GLY A 228ARG A 294HIS A 299 | SAH A 701 ( 4.2A)SAH A 701 ( 4.2A)SAH A 701 (-3.5A)NoneSAH A 701 (-4.2A) | 0.62A | 3uj7A-4kriA:38.4 | 3uj7A-4kriA:23.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kri | PHOSPHOLETHANOLAMINEN-METHYLTRANSFERASE2 (Haemonchuscontortus) |
PF08241(Methyltransf_11) | 6 | LEU A 178TYR A 183ILE A 200GLY A 228ASP A 295HIS A 299 | SAH A 701 ( 4.2A)SAH A 701 ( 4.2A)SAH A 701 ( 4.5A)SAH A 701 (-3.5A)NoneSAH A 701 (-4.2A) | 0.62A | 3uj7A-4kriA:38.4 | 3uj7A-4kriA:23.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lhb | MOLYBDOPTERINADENYLYLTRANSFERASE (Pyrococcusfuriosus) |
PF00994(MoCF_biosynth) | 5 | LEU A 65GLY A 17ILE A 19ASP A 74ALA A 73 | None | 1.33A | 3uj7A-4lhbA:undetectable | 3uj7A-4lhbA:23.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4mwz | PHOSPHOETHANOLAMINEN-METHYLTRANSFERASE,PUTATIVE (Plasmodiumvivax) |
PF13649(Methyltransf_25) | 7 | TYR A 16ILE A 33GLY A 60CYH A 84ILE A 108ARG A 124ASP A 125 | SAM A 301 ( 4.3A)SAM A 301 (-4.3A)SAM A 301 (-3.7A)BME A 303 (-1.9A)SAM A 301 (-4.0A)NoneNone | 0.72A | 3uj7A-4mwzA:41.5 | 3uj7A-4mwzA:63.53 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4mwz | PHOSPHOETHANOLAMINEN-METHYLTRANSFERASE,PUTATIVE (Plasmodiumvivax) |
PF13649(Methyltransf_25) | 8 | TYR A 16ILE A 33GLY A 60ILE A 83ILE A 108ARG A 124ASP A 125HIS A 129 | SAM A 301 ( 4.3A)SAM A 301 (-4.3A)SAM A 301 (-3.7A)SAM A 301 (-3.7A)SAM A 301 (-4.0A)NoneNoneSAM A 301 (-3.9A) | 0.18A | 3uj7A-4mwzA:41.5 | 3uj7A-4mwzA:63.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mxe | N-ACETYLTRANSFERASEESCO1 (Homo sapiens) |
PF13880(Acetyltransf_13) | 5 | GLY A 768ILE A 766ILE A 806ARG A 771ALA A 724 | None | 1.09A | 3uj7A-4mxeA:undetectable | 3uj7A-4mxeA:19.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n30 | PROTEIN DISULFIDEISOMERASE (Pseudomonasaeruginosa) |
PF13462(Thioredoxin_4) | 5 | LEU A 108GLY A 138ILE A 128ALA A 101HIS A 104 | None | 1.28A | 3uj7A-4n30A:undetectable | 3uj7A-4n30A:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o6v | OXIDOREDUCTASE,SHORT-CHAINDEHYDROGENASE/REDUCTASE FAMILY (Brucella suis) |
PF13561(adh_short_C2) | 5 | LEU A 224ILE A 132GLY A 178ILE A 204ALA A 135 | None | 1.18A | 3uj7A-4o6vA:undetectable | 3uj7A-4o6vA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oyd | APOPTOSIS REGULATORBHRF1 (Humangammaherpesvirus4) |
PF00452(Bcl-2) | 5 | LEU A 54ILE A 154GLY A 99ILE A 57ALA A 101 | None | 1.20A | 3uj7A-4oydA:undetectable | 3uj7A-4oydA:18.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p9n | CARBOXYLESTERASE (Sulfolobusshibatae) |
PF07859(Abhydrolase_3) | 5 | LEU A 198ILE A 84ILE A 203ILE A 19ALA A 152 | None | 0.98A | 3uj7A-4p9nA:3.5 | 3uj7A-4p9nA:23.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4r6w | PHOSPHOETHANOLAMINEN-METHYLTRANSFERASE (Plasmodiumfalciparum) |
PF13649(Methyltransf_25) | 7 | LEU A 14TYR A 19GLY A 63ILE A 86CYH A 87ILE A 84ARG A 127 | NoneSAH A 302 ( 4.1A)SAH A 302 (-3.7A)SAH A 302 (-3.7A)SAH A 302 (-3.4A)NoneNone | 1.34A | 3uj7A-4r6wA:46.3 | 3uj7A-4r6wA:99.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4r6w | PHOSPHOETHANOLAMINEN-METHYLTRANSFERASE (Plasmodiumfalciparum) |
PF13649(Methyltransf_25) | 10 | LEU A 14TYR A 19ILE A 36GLY A 63ILE A 86CYH A 87ILE A 111ARG A 127ALA A 129HIS A 132 | NoneSAH A 302 ( 4.1A)SAH A 302 ( 3.9A)SAH A 302 (-3.7A)SAH A 302 (-3.7A)SAH A 302 (-3.4A)SAH A 302 (-4.1A)NoneSAH A 302 (-3.3A)SAH A 302 (-4.3A) | 0.27A | 3uj7A-4r6wA:46.3 | 3uj7A-4r6wA:99.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4r6w | PHOSPHOETHANOLAMINEN-METHYLTRANSFERASE (Plasmodiumfalciparum) |
PF13649(Methyltransf_25) | 9 | LEU A 14TYR A 19ILE A 36ILE A 86CYH A 87ILE A 90ILE A 111ARG A 127HIS A 132 | NoneSAH A 302 ( 4.1A)SAH A 302 ( 3.9A)SAH A 302 (-3.7A)SAH A 302 (-3.4A)NoneSAH A 302 (-4.1A)NoneSAH A 302 (-4.3A) | 0.47A | 3uj7A-4r6wA:46.3 | 3uj7A-4r6wA:99.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s1i | PYRIDOXAL KINASE (Entamoebahistolytica) |
PF08543(Phos_pyr_kin) | 5 | LEU B 177ILE B 276ILE B 204ILE B 223ALA B 237 | None | 1.20A | 3uj7A-4s1iB:undetectable | 3uj7A-4s1iB:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wxu | MYOCILIN (Homo sapiens) |
PF02191(OLF) | 5 | TYR A 392GLY A 399ILE A 401ASP A 396ALA A 397 | None | 1.03A | 3uj7A-4wxuA:undetectable | 3uj7A-4wxuA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xe7 | UNCHARACTERIZEDPROTEIN (Bacillusthuringiensis) |
no annotation | 5 | LEU A 73ILE A 38ILE A 128ILE A 24ALA A 135 | None | 1.08A | 3uj7A-4xe7A:undetectable | 3uj7A-4xe7A:22.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xri | PUTATIVEUNCHARACTERIZEDPROTEIN (Chaetomiumthermophilum) |
PF03810(IBN_N)PF13513(HEAT_EZ) | 5 | LEU A 173ILE A 161CYH A 162ILE A 119ARG A 141 | None | 1.32A | 3uj7A-4xriA:undetectable | 3uj7A-4xriA:14.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yxm | DNA INTEGRITYSCANNING PROTEINDISA (Thermotogamaritima) |
PF00633(HHH)PF02457(DisA_N)PF10635(DisA-linker) | 5 | LEU A 80ILE A 18ILE A 78ILE A 124ALA A 27 | None | 0.94A | 3uj7A-4yxmA:undetectable | 3uj7A-4yxmA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z5q | CYTOCHROME P450HYDROXYLASE (Streptomycesatroolivaceus) |
PF00067(p450) | 5 | LEU A 157ILE A 216ILE A 237CYH A 234ALA A 107 | NoneNoneHEM A 401 (-4.5A)NoneNone | 1.26A | 3uj7A-4z5qA:undetectable | 3uj7A-4z5qA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b04 | PROBABLE TRANSLATIONINITIATION FACTOREIF-2B SUBUNIT GAMMA (Schizosaccharomycespombe) |
PF00483(NTP_transferase) | 5 | ILE E 374ILE E 400ILE E 379ILE E 430ARG E 407 | None | 1.12A | 3uj7A-5b04E:undetectable | 3uj7A-5b04E:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5czz | CRISPR-ASSOCIATEDENDONUCLEASE CAS9 (Staphylococcusaureus) |
PF13395(HNH_4)PF16592(Cas9_REC) | 5 | ILE A 676GLY A 8ILE A 21ILE A 20ALA A 705 | None | 0.93A | 3uj7A-5czzA:undetectable | 3uj7A-5czzA:14.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e02 | FRQ-INTERACTING RNAHELICASE (Neurosporacrassa) |
PF00270(DEAD)PF00271(Helicase_C)PF08148(DSHCT)PF13234(rRNA_proc-arch) | 5 | LEU A 199ILE A 311CYH A 345ILE A 337ILE A 192 | None | 1.37A | 3uj7A-5e02A:undetectable | 3uj7A-5e02A:13.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fmg | PROTEASOME SUBUNITBETA TYPE (Plasmodiumfalciparum) |
PF00227(Proteasome) | 5 | ILE M 206GLY M 38CYH M 165ILE M 41ARG M 56 | None | 1.12A | 3uj7A-5fmgM:undetectable | 3uj7A-5fmgM:23.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hdt | SISTER CHROMATIDCOHESION PROTEINPDS5 HOMOLOG B (Homo sapiens) |
no annotation | 5 | LEU A 604ILE A 449ILE A 532ASP A 538ALA A 542 | None | 1.22A | 3uj7A-5hdtA:undetectable | 3uj7A-5hdtA:12.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hws | 2-DEHYDROPANTOATE2-REDUCTASE (Thermococcuskodakarensis) |
PF02558(ApbA)PF08546(ApbA_C) | 5 | LEU A 237ILE A 210ILE A 187ILE A 214ASP A 204 | None | 1.26A | 3uj7A-5hwsA:4.6 | 3uj7A-5hwsA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i2g | DIOL DEHYDRATASE (Roseburiainulinivorans) |
PF01228(Gly_radical)PF02901(PFL-like) | 5 | LEU A 394GLY A 351ILE A 383ILE A 348ARG A 431 | None | 1.18A | 3uj7A-5i2gA:undetectable | 3uj7A-5i2gA:14.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jfc | NADH-DEPENDENTFERREDOXIN:NADPOXIDOREDUCTASESUBUNIT ALPHA (Pyrococcusfuriosus) |
PF07992(Pyr_redox_2)PF14691(Fer4_20) | 5 | LEU L 432GLY L 246ILE L 426ILE L 159ALA L 165 | NoneNoneNoneNoneFAD L 503 (-3.6A) | 1.15A | 3uj7A-5jfcL:undetectable | 3uj7A-5jfcL:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m5x | DNA-DIRECTED RNAPOLYMERASE I SUBUNITRPA135 (Saccharomycescerevisiae) |
PF00562(RNA_pol_Rpb2_6)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF06883(RNA_pol_Rpa2_4) | 5 | ILE B1151ILE B1153ARG B1134ASP B1137ALA B1138 | None | 1.26A | 3uj7A-5m5xB:undetectable | 3uj7A-5m5xB:12.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mz6 | SEPARASE (Caenorhabditiselegans) |
PF03568(Peptidase_C50) | 5 | LEU 1 819ILE 1 828GLY 1 841ILE 1 744ALA 1 843 | None | 1.34A | 3uj7A-5mz61:undetectable | 3uj7A-5mz61:12.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u4s | PUTATIVE SHORT CHAINDEHYDROGENASE (Burkholderiacenocepacia) |
PF00106(adh_short) | 5 | LEU A 26GLY A 18ILE A 77ARG A 15ALA A 13 | NoneNoneNoneNAP A 300 (-4.2A)None | 1.28A | 3uj7A-5u4sA:5.5 | 3uj7A-5u4sA:18.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vj7 | OXIDOREDUCTASE (Pyrococcusfuriosus) |
PF07992(Pyr_redox_2)PF14691(Fer4_20) | 5 | LEU A 433GLY A 246ILE A 427ILE A 159ALA A 165 | NoneNoneNoneNoneFAD A 503 (-3.8A) | 1.15A | 3uj7A-5vj7A:undetectable | 3uj7A-5vj7A:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wp4 | PHOSPHOETHANOLAMINEN-METHYLTRANSFERASE1 (Arabidopsisthaliana) |
no annotation | 6 | LEU A 241TYR A 246GLY A 290ARG A 355ASP A 356HIS A 360 | SAH A 703 (-4.0A)SAH A 703 ( 4.0A)SAH A 703 (-4.0A)None PC A 702 ( 4.6A)SAH A 703 (-4.0A) | 0.43A | 3uj7A-5wp4A:40.0 | 3uj7A-5wp4A:23.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wp4 | PHOSPHOETHANOLAMINEN-METHYLTRANSFERASE1 (Arabidopsisthaliana) |
no annotation | 5 | LEU A 241TYR A 246GLY A 290ILE A 311ARG A 355 | SAH A 703 (-4.0A)SAH A 703 ( 4.0A)SAH A 703 (-4.0A)NoneNone | 1.08A | 3uj7A-5wp4A:40.0 | 3uj7A-5wp4A:23.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wp4 | PHOSPHOETHANOLAMINEN-METHYLTRANSFERASE1 (Arabidopsisthaliana) |
no annotation | 5 | LEU A 241TYR A 246ILE A 251ARG A 355ASP A 356 | SAH A 703 (-4.0A)SAH A 703 ( 4.0A)NoneNone PC A 702 ( 4.6A) | 1.15A | 3uj7A-5wp4A:40.0 | 3uj7A-5wp4A:23.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wp4 | PHOSPHOETHANOLAMINEN-METHYLTRANSFERASE1 (Arabidopsisthaliana) |
no annotation | 5 | LEU A 375ILE A 352ILE A 383ASP A 425ALA A 488 | None | 1.29A | 3uj7A-5wp4A:40.0 | 3uj7A-5wp4A:23.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wp5 | PHOSPHOMETHYLETHANOLAMINEN-METHYLTRANSFERASE2 (Arabidopsisthaliana) |
no annotation | 5 | LEU A 375ILE A 352ILE A 383ASP A 425ALA A 488 | None | 1.37A | 3uj7A-5wp5A:33.2 | 3uj7A-5wp5A:23.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x7n | DIAMINOPIMELATEDECARBOXYLASE (Corynebacteriumglutamicum) |
no annotation | 5 | LEU A 91ILE A 82GLY A 301CYH A 57ALA A 73 | NoneNonePLP A 504 (-3.4A)NonePLP A 504 ( 3.8A) | 1.22A | 3uj7A-5x7nA:undetectable | 3uj7A-5x7nA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xvd | HYDROGENASE-2 SMALLCHAIN (Citrobacter sp.MGH106) |
no annotation | 5 | LEU S 143ILE S 100ILE S 114ILE S 115ALA S 121 | None | 1.22A | 3uj7A-5xvdS:undetectable | 3uj7A-5xvdS:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y6t | ENDO-1,4-BETA-MANNANASE (Eisenia fetida) |
no annotation | 5 | LEU A 124ILE A 67GLY A 75ILE A 374ILE A 372 | None | 1.21A | 3uj7A-5y6tA:undetectable | 3uj7A-5y6tA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ykd | D-HYDANTOINASE/DIHYDROPYRIMIDINASE (Pseudomonasaeruginosa) |
no annotation | 5 | LEU A 51ILE A 5ILE A 31ASP A 390ALA A 391 | None | 0.88A | 3uj7A-5ykdA:undetectable | 3uj7A-5ykdA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6at7 | PHENYLALANINEAMMONIA-LYASE (Sorghum bicolor) |
no annotation | 5 | LEU A 181GLY A 201ILE A 199ILE A 203ALA A 209 | None | 1.14A | 3uj7A-6at7A:undetectable | 3uj7A-6at7A:undetectable |