SIMILAR PATTERNS OF AMINO ACIDS FOR 3UBO_B_ADNB353_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ae1 | TROPINONEREDUCTASE-I (Daturastramonium) |
PF13561(adh_short_C2) | 4 | SER A 158ILE A 33TYR A 171GLY A 202 | NAP A 274 (-3.4A)NAP A 274 (-3.9A)NAP A 274 (-4.7A)None | 0.96A | 3uboB-1ae1A:7.1 | 3uboB-1ae1A:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g0n | TRIHYDROXYNAPHTHALENE REDUCTASE (Magnaporthegrisea) |
PF13561(adh_short_C2) | 4 | SER A 164ILE A 41TYR A 178GLY A 209 | PHH A 402 (-2.2A)NDP A 400 (-4.1A)PHH A 402 ( 4.0A)PHH A 402 (-4.3A) | 1.05A | 3uboB-1g0nA:6.6 | 3uboB-1g0nA:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h74 | HOMOSERINE KINASE (Methanocaldococcusjannaschii) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 4 | SER A 97ILE A 176GLY A 88PRO A 32 | ADP A 400 (-3.5A)NoneNoneNone | 1.04A | 3uboB-1h74A:undetectable | 3uboB-1h74A:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ipf | TROPINONEREDUCTASE-II (Daturastramonium) |
PF13561(adh_short_C2) | 4 | SER A 146ILE A 21TYR A 159GLY A 190 | TNE A 262 ( 2.9A)NDP A 261 (-4.1A)TNE A 262 ( 4.2A)NDP A 261 ( 4.9A) | 0.96A | 3uboB-1ipfA:6.4 | 3uboB-1ipfA:24.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ipf | TROPINONEREDUCTASE-II (Daturastramonium) |
PF13561(adh_short_C2) | 4 | SER A 148ILE A 144TYR A 159GLY A 190 | TNE A 262 (-2.9A)NDP A 261 (-4.6A)TNE A 262 ( 4.2A)NDP A 261 ( 4.9A) | 0.99A | 3uboB-1ipfA:6.4 | 3uboB-1ipfA:24.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j8s | PYELONEPHRITICADHESIN (Escherichiacoli) |
PF03627(PapG_N) | 4 | SER A 165ILE A 4TYR A 166GLY A 46 | None | 0.97A | 3uboB-1j8sA:undetectable | 3uboB-1j8sA:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ja9 | 1,3,6,8-TETRAHYDROXYNAPHTHALENEREDUCTASE (Magnaporthegrisea) |
PF13561(adh_short_C2) | 4 | SER A 164ILE A 41TYR A 178GLY A 209 | PYQ A 406 ( 2.7A)NDP A 402 (-4.0A)PYQ A 406 ( 4.3A)PYQ A 406 (-4.1A) | 0.99A | 3uboB-1ja9A:6.7 | 3uboB-1ja9A:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jjf | ENDO-1,4-BETA-XYLANASE Z (Ruminiclostridiumthermocellum) |
PF00756(Esterase) | 4 | ILE A 168TYR A 202GLY A 175PRO A 194 | None | 1.03A | 3uboB-1jjfA:3.2 | 3uboB-1jjfA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ktw | IOTA-CARRAGEENASE (Alteromonas sp.ATCC 43554) |
PF12708(Pectate_lyase_3) | 4 | SER A 201ILE A 262TYR A 170GLY A 225 | None | 0.97A | 3uboB-1ktwA:undetectable | 3uboB-1ktwA:23.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mdf | 2,3-DIHYDROXYBENZOATE-AMP LIGASE (Bacillussubtilis) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | SER A 214ILE A 275TYR A 339GLY A 245 | None | 1.01A | 3uboB-1mdfA:undetectable | 3uboB-1mdfA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mg5 | ALCOHOLDEHYDROGENASE (Drosophilamelanogaster) |
PF00106(adh_short) | 4 | SER A 139ILE A 18TYR A 152GLY A 183 | ACT A 900 ( 2.9A)NAI A 850 (-3.9A)ACT A 900 ( 4.2A)NAI A 850 (-4.9A) | 1.06A | 3uboB-1mg5A:4.8 | 3uboB-1mg5A:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n5d | CARBONYLREDUCTASE/20BETA-HYDROXYSTEROIDDEHYDROGENASE (Sus scrofa) |
PF00106(adh_short) | 4 | SER A 139ILE A 16TYR A 193GLY A 228 | NDP A 300 (-3.5A)NDP A 300 (-3.6A)NDP A 300 (-4.8A)None | 0.94A | 3uboB-1n5dA:5.9 | 3uboB-1n5dA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uxt | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE(NADP+) (Thermoproteustenax) |
PF00171(Aldedh) | 4 | SER A 322ILE A 289GLY A 365PRO A 376 | None | 1.00A | 3uboB-1uxtA:3.2 | 3uboB-1uxtA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uzn | 3-OXOACYL-[ACYL-CARRIER PROTEIN]REDUCTASE (Mycobacteriumtuberculosis) |
PF13561(adh_short_C2) | 4 | SER A 140ILE A 27TYR A 153GLY A 184 | NoneNAP A1249 (-4.1A)NoneNone | 0.94A | 3uboB-1uznA:6.6 | 3uboB-1uznA:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vl0 | DTDP-4-DEHYDRORHAMNOSE REDUCTASE, RFBDORTHOLOG (Clostridiumacetobutylicum) |
PF04321(RmlD_sub_bind) | 4 | SER A 100ILE A 96GLY A 132PRO A 82 | None | 1.02A | 3uboB-1vl0A:3.8 | 3uboB-1vl0A:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x1e | 2-DEOXY-D-GLUCONATE3-DEHYDROGENASE (Thermusthermophilus) |
PF13561(adh_short_C2) | 4 | SER A 129ILE A 14TYR A 144GLY A 175 | None | 0.90A | 3uboB-1x1eA:7.0 | 3uboB-1x1eA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zjy | R-SPECIFIC ALCOHOLDEHYDROGENASE (Lactobacillusbrevis) |
PF13561(adh_short_C2) | 4 | SER A 142ILE A 18TYR A 155GLY A 188 | NAI A1270 ( 3.8A)NAI A1270 (-3.6A)SS2 A1260 ( 4.2A)None | 1.02A | 3uboB-1zjyA:6.5 | 3uboB-1zjyA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a9f | PUTATIVE MALICENZYME((S)-MALATE:NAD+OXIDOREDUCTASE(DECARBOXYLATING)) (Streptococcuspyogenes) |
PF00390(malic)PF03949(Malic_M) | 4 | SER A 277ILE A 285GLY A 304PRO A 283 | None | 1.05A | 3uboB-2a9fA:3.1 | 3uboB-2a9fA:24.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aaa | ALPHA-AMYLASE (Aspergillusniger) |
PF00128(Alpha-amylase)PF09260(DUF1966) | 4 | SER A 401ILE A 406TYR A 382GLY A 427 | None | 0.97A | 3uboB-2aaaA:4.2 | 3uboB-2aaaA:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c07 | 3-OXOACYL-(ACYL-CARRIER PROTEIN)REDUCTASE (Plasmodiumfalciparum) |
PF13561(adh_short_C2) | 4 | SER A 199ILE A 75TYR A 212GLY A 243 | None | 1.05A | 3uboB-2c07A:6.5 | 3uboB-2c07A:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d07 | G/TMISMATCH-SPECIFICTHYMINE DNAGLYCOSYLASE (Homo sapiens) |
PF03167(UDG) | 4 | SER A 272ILE A 139TYR A 152GLY A 231 | None | 1.03A | 3uboB-2d07A:undetectable | 3uboB-2d07A:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hrb | CARBONYL REDUCTASE[NADPH] 3 (Homo sapiens) |
PF00106(adh_short) | 4 | SER A 140ILE A 17TYR A 194GLY A 229 | NAP A1001 ( 4.0A)NAP A1001 (-3.8A)NAP A1001 ( 4.7A)None | 0.93A | 3uboB-2hrbA:5.8 | 3uboB-2hrbA:23.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2irw | CORTICOSTEROID11-BETA-DEHYDROGENASE ISOZYME 1 (Homo sapiens) |
PF00106(adh_short) | 4 | SER A 170ILE A 46TYR A 183GLY A 216 | NN4 A 911 ( 2.8A)NAP A 901 (-4.0A)NN4 A 911 ( 4.0A)NN4 A 911 (-4.1A) | 1.04A | 3uboB-2irwA:6.7 | 3uboB-2irwA:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2m0y | DEDICATOR OFCYTOKINESIS PROTEIN1 (Mus musculus) |
PF14604(SH3_9) | 4 | SER A 63ILE A 38TYR A 64GLY A 44 | None | 1.05A | 3uboB-2m0yA:undetectable | 3uboB-2m0yA:11.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mev | MENGO VIRUS COATPROTEIN (SUBUNITVP3) (Cardiovirus A) |
PF00073(Rhv) | 4 | ILE 3 165TYR 3 104GLY 3 185PRO 3 131 | None | 1.03A | 3uboB-2mev3:undetectable | 3uboB-2mev3:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o04 | PECTATE LYASE (Bacillussubtilis) |
PF00544(Pec_lyase_C) | 4 | SER A 316ILE A 250GLY A 311PRO A 281 | NoneADA A 401 (-4.3A)NoneNone | 1.05A | 3uboB-2o04A:undetectable | 3uboB-2o04A:19.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oua | SERINE PROTEASE (Nocardiopsisalba) |
PF00089(Trypsin) | 4 | SER A 110ILE A 16GLY A 108PRO A 50 | None | 0.83A | 3uboB-2ouaA:undetectable | 3uboB-2ouaA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p68 | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]REDUCTASE (Aquifexaeolicus) |
PF13561(adh_short_C2) | 4 | SER A 144ILE A 19TYR A 157GLY A 188 | None | 1.02A | 3uboB-2p68A:6.5 | 3uboB-2p68A:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ph3 | 3-OXOACYL-[ACYLCARRIER PROTEIN]REDUCTASE (Thermusthermophilus) |
PF13561(adh_short_C2) | 4 | SER A 139ILE A 13TYR A 152GLY A 183 | None | 1.03A | 3uboB-2ph3A:7.2 | 3uboB-2ph3A:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qwu | INTRACELLULAR GROWTHLOCUS, SUBUNIT C (Francisellatularensis) |
PF11550(IglC) | 4 | SER A 157ILE A 120GLY A 182PRO A 150 | None | 0.86A | 3uboB-2qwuA:undetectable | 3uboB-2qwuA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uvd | 3-OXOACYL-(ACYL-CARRIER-PROTEIN)REDUCTASE (Bacillusanthracis) |
PF13561(adh_short_C2) | 4 | SER A 141ILE A 16TYR A 154GLY A 185 | None | 1.00A | 3uboB-2uvdA:6.9 | 3uboB-2uvdA:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yhg | CELLULOSE-BINDINGPROTEIN (Saccharophagusdegradans) |
PF07632(DUF1593) | 4 | SER A 799ILE A 807GLY A 764PRO A 742 | MG A1939 (-4.4A)NoneNoneNone | 1.04A | 3uboB-2yhgA:undetectable | 3uboB-2yhgA:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z5l | TYLACTONE SYNTHASESTARTER MODULE ANDMODULES 1 & 2 (Streptomycesfradiae) |
PF08659(KR) | 4 | SER A 370ILE A 250TYR A 383GLY A 410 | None | 1.04A | 3uboB-2z5lA:5.0 | 3uboB-2z5lA:24.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zat | DEHYDROGENASE/REDUCTASE SDR FAMILYMEMBER 4 (Sus scrofa) |
PF13561(adh_short_C2) | 4 | SER A 151ILE A 26TYR A 164GLY A 195 | NAP A1261 ( 3.4A)NAP A1261 ( 3.7A)NAP A1261 ( 4.6A)None | 1.04A | 3uboB-2zatA:7.1 | 3uboB-2zatA:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ai2 | NADPH-SORBOSEREDUCTASE (Gluconobacterfrateurii) |
PF13561(adh_short_C2) | 4 | SER A 144ILE A 19TYR A 157GLY A 188 | NDP A 270 ( 3.7A)NDP A 270 (-3.7A)NDP A 270 (-4.6A)None | 1.03A | 3uboB-3ai2A:7.1 | 3uboB-3ai2A:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bhi | CARBONYL REDUCTASE[NADPH] 1 (Homo sapiens) |
PF00106(adh_short) | 4 | SER A 139ILE A 16TYR A 193GLY A 228 | NAP A 309 ( 3.8A)NAP A 309 (-3.8A)NAP A 309 (-4.8A) CL A 308 ( 3.9A) | 0.94A | 3uboB-3bhiA:5.5 | 3uboB-3bhiA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dwf | 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 (Cavia porcellus) |
PF00106(adh_short) | 4 | SER A 170ILE A 46TYR A 183GLY A 216 | NAP A 301 (-3.4A)NAP A 301 (-3.8A)NAP A 301 (-4.8A)GOL A 9 (-4.6A) | 1.04A | 3uboB-3dwfA:6.5 | 3uboB-3dwfA:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f1k | UNCHARACTERIZEDOXIDOREDUCTASE YCIK (Escherichiacoli) |
PF00106(adh_short) | 4 | SER A 152ILE A 24TYR A 165GLY A 195 | NAP A 300 ( 3.7A)NAP A 300 (-3.5A)NAP A 300 (-4.6A)NAP A 300 (-4.7A) | 0.93A | 3uboB-3f1kA:5.8 | 3uboB-3f1kA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hba | PUTATIVEPHOSPHOSUGARISOMERASE (Shewanelladenitrificans) |
PF01380(SIS) | 4 | SER A 102ILE A 133GLY A 100PRO A 129 | None | 0.82A | 3uboB-3hbaA:3.8 | 3uboB-3hbaA:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hmj | FATTY ACID SYNTHASESUBUNIT ALPHA (Saccharomycescerevisiae) |
PF00109(ketoacyl-synt)PF01648(ACPS)PF02801(Ketoacyl-synt_C) | 4 | SER A 827ILE A 688TYR A 839GLY A 870 | None | 1.02A | 3uboB-3hmjA:4.5 | 3uboB-3hmjA:11.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i1j | OXIDOREDUCTASE,SHORT CHAINDEHYDROGENASE/REDUCTASE FAMILY (Pseudomonassyringae groupgenomosp. 3) |
PF00106(adh_short) | 4 | SER A 153ILE A 25TYR A 166GLY A 198 | ACT A 248 (-2.4A)NoneEDO A 249 (-4.4A)None | 0.90A | 3uboB-3i1jA:6.3 | 3uboB-3i1jA:24.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iah | SHORT CHAINDEHYDROGENASE YCIK (Salmonellaenterica) |
PF00106(adh_short) | 4 | SER A 152ILE A 24TYR A 165GLY A 196 | ACT A 255 (-2.6A)NAP A 254 (-3.9A)ACT A 255 ( 4.3A)NAP A 254 (-4.6A) | 0.85A | 3uboB-3iahA:5.6 | 3uboB-3iahA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3icc | PUTATIVE3-OXOACYL-(ACYLCARRIER PROTEIN)REDUCTASE (Bacillusanthracis) |
PF13561(adh_short_C2) | 4 | SER A 145ILE A 16TYR A 158GLY A 189 | SER A 145 (-0.0A)ILE A 16 (-0.7A)TYR A 158 (-1.3A)GLY A 189 (-0.0A) | 1.04A | 3uboB-3iccA:6.9 | 3uboB-3iccA:23.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lyl | 3-OXOACYL-(ACYL-CARRIER-PROTEIN)REDUCTASE (Francisellatularensis) |
PF13561(adh_short_C2) | 4 | SER A 141ILE A 17TYR A 154GLY A 185 | None | 1.00A | 3uboB-3lylA:6.9 | 3uboB-3lylA:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o03 | DEHYDROGENASE WITHDIFFERENTSPECIFICITIES (Streptococcussuis) |
PF13561(adh_short_C2) | 4 | SER A 150ILE A 26TYR A 163GLY A 194 | GCO A 274 ( 2.6A)NAP A 273 (-3.8A)GCO A 274 ( 4.2A) CA A 272 (-4.5A) | 0.94A | 3uboB-3o03A:6.6 | 3uboB-3o03A:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o26 | SALUTARIDINEREDUCTASE (Papaversomniferum) |
PF00106(adh_short)PF13561(adh_short_C2) | 4 | SER A 180ILE A 24TYR A 236GLY A 265 | NDP A 312 ( 4.3A)NDP A 312 (-3.9A)NDP A 312 (-4.7A)None | 0.80A | 3uboB-3o26A:6.5 | 3uboB-3o26A:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3osu | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]REDUCTASE (Staphylococcusaureus) |
PF13561(adh_short_C2) | 4 | SER A 141ILE A 16TYR A 154GLY A 185 | PEG A 247 ( 4.5A)NonePEG A 247 (-4.2A)None | 1.04A | 3uboB-3osuA:6.7 | 3uboB-3osuA:24.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pv4 | DEGQ (Legionellafallonii) |
PF13180(PDZ_2)PF13365(Trypsin_2) | 4 | SER A 193ILE A 20GLY A 67PRO A 148 | None | 1.04A | 3uboB-3pv4A:undetectable | 3uboB-3pv4A:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rwb | PYRIDOXAL4-DEHYDROGENASE (Mesorhizobiumloti) |
PF13561(adh_short_C2) | 4 | SER A 141ILE A 19TYR A 154GLY A 185 | 4PL A 252 (-2.7A)NAD A 251 (-3.9A)NAD A 251 ( 4.5A)4PL A 252 (-4.2A) | 0.93A | 3uboB-3rwbA:7.0 | 3uboB-3rwbA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tox | SHORT CHAINDEHYDROGENASE (Sinorhizobiummeliloti) |
PF13561(adh_short_C2) | 4 | SER A 145ILE A 20TYR A 159GLY A 190 | NAP A 601 (-3.3A)NAP A 601 (-3.9A)NAP A 601 (-4.7A)None | 0.93A | 3uboB-3toxA:6.3 | 3uboB-3toxA:28.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tzq | SHORT-CHAIN TYPEDEHYDROGENASE/REDUCTASE (Mycobacteriummarinum) |
no annotation | 4 | SER B 142ILE B 19TYR B 155GLY B 186 | GOL B 268 ( 3.8A)NoneNoneGOL B 268 (-3.7A) | 0.90A | 3uboB-3tzqB:6.9 | 3uboB-3tzqB:23.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u0b | OXIDOREDUCTASE,SHORT CHAINDEHYDROGENASE/REDUCTASE FAMILY PROTEIN (Mycolicibacteriumsmegmatis) |
PF13561(adh_short_C2) | 4 | SER A 343ILE A 221TYR A 356GLY A 387 | None | 1.01A | 3uboB-3u0bA:6.1 | 3uboB-3u0bA:24.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uf0 | SHORT-CHAINDEHYDROGENASE/REDUCTASE SDR (Beutenbergiacavernae) |
PF13561(adh_short_C2) | 4 | SER A 143ILE A 21TYR A 156GLY A 187 | NAP A 274 (-3.5A)NAP A 274 (-3.7A)NAP A 274 (-4.7A)None | 0.94A | 3uboB-3uf0A:6.8 | 3uboB-3uf0A:23.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v2g | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]REDUCTASE (Sinorhizobiummeliloti) |
PF13561(adh_short_C2) | 4 | SER A 166ILE A 43TYR A 180GLY A 211 | None | 1.05A | 3uboB-3v2gA:6.9 | 3uboB-3v2gA:24.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vzq | ACETOACETYL-COAREDUCTASE (Cupriavidusnecator) |
PF00106(adh_short) | 4 | SER A 140ILE A 15TYR A 153GLY A 184 | None | 1.05A | 3uboB-3vzqA:6.9 | 3uboB-3vzqA:23.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wbx | PUTATIVE2,5-DIKETO-D-GLUCONIC ACID REDUCTASE (Gluconobacteroxydans) |
PF00248(Aldo_ket_red) | 4 | SER A 143ILE A 153GLY A 141PRO A 161 | None | 1.05A | 3uboB-3wbxA:3.2 | 3uboB-3wbxA:23.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wxb | UNCHARACTERIZEDPROTEIN (Gallus gallus) |
PF00106(adh_short) | 4 | SER A 159ILE A 18TYR A 178GLY A 209 | EDO A 301 ( 2.5A)NDP A 300 (-4.0A)EDO A 301 ( 4.3A)None | 0.89A | 3uboB-3wxbA:5.6 | 3uboB-3wxbA:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4avy | PROBABLE SHORT-CHAINDEHYDROGENASE (Pseudomonasaeruginosa) |
PF13561(adh_short_C2) | 4 | SER A 133ILE A 22TYR A 146GLY A 177 | None | 0.85A | 3uboB-4avyA:6.7 | 3uboB-4avyA:23.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dqx | PROBABLEOXIDOREDUCTASEPROTEIN (Rhizobium etli) |
PF13561(adh_short_C2) | 4 | SER A 160ILE A 39TYR A 173GLY A 204 | None | 1.00A | 3uboB-4dqxA:7.1 | 3uboB-4dqxA:19.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4e3a | SUGAR KINASE PROTEIN (Rhizobium etli) |
PF00294(PfkB) | 5 | SER A 58ILE A 115TYR A 156GLY A 273PRO A 312 | ADN A 500 (-3.3A)NoneADN A 500 (-3.8A)ADN A 500 (-3.9A)ADN A 500 (-4.3A) | 0.40A | 3uboB-4e3aA:59.3 | 3uboB-4e3aA:71.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f4w | DNA POLYMERASE IV (Sulfolobusacidocaldarius;Sulfolobussolfataricus) |
PF00817(IMS)PF11798(IMS_HHH) | 4 | SER A 308ILE A 285GLY A 306PRO A 282 | None | 1.00A | 3uboB-4f4wA:undetectable | 3uboB-4f4wA:25.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iin | 3-KETOACYL-ACYLCARRIER PROTEINREDUCTASE (FABG) (Helicobacterpylori) |
PF13561(adh_short_C2) | 4 | SER A 142ILE A 17TYR A 155GLY A 186 | NAD A 301 (-3.4A)NAD A 301 (-3.6A)NAD A 301 (-4.7A)None | 1.03A | 3uboB-4iinA:6.6 | 3uboB-4iinA:23.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iiv | 3-OXOACYL-[ACYL-CARRIER PROTEIN]REDUCTASE (Escherichiacoli) |
PF13561(adh_short_C2) | 4 | SER A 140ILE A 14TYR A 153GLY A 184 | NAP A1901 ( 3.7A)NAP A1901 (-4.0A)NAP A1901 (-4.6A)NAP A1901 (-4.9A) | 1.01A | 3uboB-4iivA:6.8 | 3uboB-4iivA:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4imr | 3-OXOACYL-(ACYL-CARRIER-PROTEIN)REDUCTASE (Agrobacteriumfabrum) |
PF13561(adh_short_C2) | 4 | SER A 146ILE A 23TYR A 159GLY A 190 | NAP A 300 ( 3.8A)NAP A 300 (-4.0A)NAP A 300 (-4.4A)NAP A 300 (-4.9A) | 0.99A | 3uboB-4imrA:6.7 | 3uboB-4imrA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j2h | SHORT CHAIN ALCOHOLDEHYDROGENASE-RELATED DEHYDROGENASE (Sinorhizobiummeliloti) |
PF13561(adh_short_C2) | 4 | SER A 146ILE A 22TYR A 159GLY A 190 | EDO A 303 (-2.7A)None1PE A 307 (-3.6A)EDO A 303 (-3.9A) | 0.96A | 3uboB-4j2hA:6.7 | 3uboB-4j2hA:23.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jro | FABG PROTEIN (Listeriamonocytogenes) |
PF13561(adh_short_C2) | 4 | SER A 142ILE A 17TYR A 155GLY A 186 | None | 0.98A | 3uboB-4jroA:7.0 | 3uboB-4jroA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lvu | OXIDOREDUCTASE,SHORT CHAINDEHYDROGENASE/REDUCTASE FAMILY (Burkholderiathailandensis) |
PF13561(adh_short_C2) | 4 | SER A 165ILE A 41TYR A 178GLY A 209 | None | 0.91A | 3uboB-4lvuA:6.7 | 3uboB-4lvuA:23.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m02 | SERINE-RICH ADHESINFOR PLATELETS (Staphylococcusaureus) |
PF05345(He_PIG) | 4 | SER A 619ILE A 586GLY A 617PRO A 615 | None | 1.05A | 3uboB-4m02A:undetectable | 3uboB-4m02A:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mfz | DBV8 PROTEIN (Nonomuraeagerenzanensis) |
no annotation | 4 | SER A 146ILE A 58GLY A 144PRO A 51 | None | 1.03A | 3uboB-4mfzA:undetectable | 3uboB-4mfzA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nbr | HYPOTHETICAL3-OXOACYL-(ACYL-CARRIER PROTEIN)REDUCTASE (Brucellaabortus) |
PF13561(adh_short_C2) | 4 | SER A 158ILE A 31TYR A 172GLY A 203 | GOL A 301 ( 3.8A)NoneGOL A 301 ( 4.7A)GOL A 301 (-4.7A) | 0.99A | 3uboB-4nbrA:6.4 | 3uboB-4nbrA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nbu | 3-OXOACYL-(ACYL-CARRIER-PROTEIN)REDUCTASE (Bacillus sp.SG-1) |
PF13561(adh_short_C2) | 4 | SER A 145ILE A 25TYR A 158GLY A 189 | NAI A 301 (-3.3A)NAI A 301 (-3.8A)NAI A 301 (-4.5A)NAI A 301 (-4.8A) | 0.93A | 3uboB-4nbuA:7.1 | 3uboB-4nbuA:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nbv | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]REDUCTASE PUTATIVESHORT-CHAINDEHYDROGENASES/REDUCTASES (SDR) FAMILYPROTEIN (Cupriavidustaiwanensis) |
PF13561(adh_short_C2) | 4 | SER A 141ILE A 17TYR A 154GLY A 185 | None | 1.01A | 3uboB-4nbvA:6.8 | 3uboB-4nbvA:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nbw | SHORT-CHAINDEHYDROGENASE/REDUCTASE SDR (Plesiocystispacifica) |
PF13561(adh_short_C2) | 4 | SER A 157ILE A 24TYR A 170GLY A 201 | NAD A 301 (-2.6A)NAD A 301 (-3.2A)NAD A 301 (-4.6A)NAD A 301 (-4.6A) | 0.94A | 3uboB-4nbwA:7.1 | 3uboB-4nbwA:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oso | REDUCTASE HOMOLOG (Streptomycescyanogenus) |
PF13561(adh_short_C2) | 4 | SER A 147ILE A 18TYR A 160GLY A 191 | 2V4 A 302 (-2.5A)NAP A 301 (-3.6A)2V4 A 302 ( 4.4A)2V4 A 302 ( 3.5A) | 0.96A | 3uboB-4osoA:6.8 | 3uboB-4osoA:24.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4osp | OXYGENASE-REDUCTASE (Streptomycesfradiae) |
PF13561(adh_short_C2) | 4 | SER A 147ILE A 18TYR A 160GLY A 191 | 2V4 A 302 ( 3.0A)NAP A 301 (-3.9A)NAP A 301 ( 4.3A)2V4 A 302 (-3.8A) | 0.98A | 3uboB-4ospA:6.9 | 3uboB-4ospA:23.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q22 | GLYCOSIDE HYDROLASEFAMILY 18 (Serratiaproteamaculans) |
PF00704(Glyco_hydro_18) | 4 | SER A 57ILE A 148TYR A 28GLY A 59 | NoneNoneACT A 502 (-3.4A)None | 0.96A | 3uboB-4q22A:2.2 | 3uboB-4q22A:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r7y | MINICHROMOSOMEMAINTENANCE PROTEINMCM, CELL DIVISIONCONTROL PROTEIN 21 (Pyrococcusfuriosus;Sulfolobussolfataricus) |
PF00493(MCM)PF14551(MCM_N)PF17207(MCM_OB) | 4 | SER A 50ILE A 63GLY A 102PRO A 104 | None | 0.84A | 3uboB-4r7yA:undetectable | 3uboB-4r7yA:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rzh | 3-OXOACYL-[ACYL-CARRIER PROTEIN]REDUCTASE (Synechocystissp. PCC 6803) |
PF13561(adh_short_C2) | 4 | SER A 143ILE A 18TYR A 156GLY A 187 | None | 0.97A | 3uboB-4rzhA:7.7 | 3uboB-4rzhA:24.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rzi | 3-KETOACYL-ACYLCARRIER PROTEINREDUCTASE (Synechocystissp. PCC 6803) |
no annotation | 4 | SER B 134ILE B 20TYR B 147GLY B 178 | None | 1.02A | 3uboB-4rziB:6.7 | 3uboB-4rziB:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wec | SHORT CHAINDEHYDROGENASE (Mycolicibacteriumsmegmatis) |
PF13561(adh_short_C2) | 4 | SER A 142ILE A 21TYR A 156GLY A 187 | NAD A 301 (-3.6A)NAD A 301 (-3.9A)NAD A 301 (-4.3A)None | 1.00A | 3uboB-4wecA:6.4 | 3uboB-4wecA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wk4 | INTEGRIN ALPHA-5 (Homo sapiens) |
PF01839(FG-GAP) | 4 | SER A 229TYR A 261GLY A 190PRO A 183 | NoneNAG A 505 (-4.2A)NoneNone | 1.05A | 3uboB-4wk4A:undetectable | 3uboB-4wk4A:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z9x | GLUCONATE5-DEHYDROGENASE (Streptococcuspyogenes) |
PF13561(adh_short_C2) | 4 | SER A 145ILE A 21TYR A 158GLY A 189 | None | 0.96A | 3uboB-4z9xA:6.8 | 3uboB-4z9xA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a22 | VESICULAR STOMATITISVIRUS L POLYMERASE (Vesicularstomatitisvirus) |
PF00946(Mononeg_RNA_pol)PF14314(Methyltrans_Mon)PF14318(Mononeg_mRNAcap) | 4 | ILE A1892TYR A1650GLY A1886PRO A1888 | None | 1.03A | 3uboB-5a22A:3.4 | 3uboB-5a22A:10.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cej | 3-OXOACYL-[ACYL-CARRIER PROTEIN]REDUCTASE (Yersinia pestis) |
PF13561(adh_short_C2) | 4 | SER A 138ILE A 17TYR A 151GLY A 182 | None | 1.04A | 3uboB-5cejA:6.8 | 3uboB-5cejA:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jla | PUTATIVE SHORT-CHAINDEHYDROGENASE/REDUCTASE (Paraburkholderiaxenovorans) |
PF13561(adh_short_C2) | 4 | SER A 141ILE A 21TYR A 153GLY A 184 | NAD A 401 (-3.3A)NAD A 401 (-3.8A)NAD A 401 (-4.4A)NAD A 401 (-4.9A) | 1.05A | 3uboB-5jlaA:6.1 | 3uboB-5jlaA:25.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lc5 | NADH DEHYDROGENASE[UBIQUINONE]IRON-SULFUR PROTEIN2, MITOCHONDRIAL (Bos taurus) |
PF00346(Complex1_49kDa) | 4 | SER D 119ILE D 128GLY D 198PRO D 130 | None | 1.05A | 3uboB-5lc5D:undetectable | 3uboB-5lc5D:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mdx | PHOTOSYSTEM IIPROTEIN D1 (Arabidopsisthaliana) |
PF00124(Photo_RC) | 4 | SER A 177ILE A 83GLY A 175PRO A 173 | None | 0.94A | 3uboB-5mdxA:undetectable | 3uboB-5mdxA:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mln | ALCOHOLDEHYDROGENASE 3 ([Candida]magnoliae) |
no annotation | 4 | SER A 144ILE A 16TYR A 157GLY A 188 | NAP A 301 (-3.5A)NAP A 301 (-3.9A)NAP A 301 (-4.7A)NAP A 301 (-4.8A) | 1.05A | 3uboB-5mlnA:6.8 | 3uboB-5mlnA:12.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mq6 | PYRIDINENUCLEOTIDE-DISULFIDEOXIDOREDUCTASE-LIKEPROTEIN (Thermothelomycesthermophila) |
PF07992(Pyr_redox_2) | 4 | ILE A 552TYR A 640GLY A 518PRO A 531 | None | 0.80A | 3uboB-5mq6A:undetectable | 3uboB-5mq6A:22.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oc1 | ARYL-ALCOHOL OXIDASE (Pleurotuseryngii) |
no annotation | 4 | SER A 311ILE A 425GLY A 423PRO A 440 | None | 0.97A | 3uboB-5oc1A:undetectable | 3uboB-5oc1A:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ovk | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]REDUCTASE FABG (Mycolicibacteriumsmegmatis) |
no annotation | 4 | SER A 148ILE A 35TYR A 161GLY A 192 | NoneNDP A 301 ( 4.5A)NoneNone | 0.96A | 3uboB-5ovkA:6.3 | 3uboB-5ovkA:15.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ovl | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]REDUCTASE FABG (Mycolicibacteriumsmegmatis) |
no annotation | 4 | SER A 148ILE A 35TYR A 161GLY A 192 | NAP A1001 (-3.6A)NAP A1001 (-4.0A)NAP A1001 (-4.6A)NAP A1001 (-4.9A) | 1.01A | 3uboB-5ovlA:6.2 | 3uboB-5ovlA:14.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t5q | SHORT-CHAINDEHYDROGENASE/REDUCTASESDR:GLUCOSE/RIBITOLDEHYDROGENASE (Brucellaabortus) |
PF13561(adh_short_C2) | 4 | SER A 140ILE A 19TYR A 153GLY A 183 | NAD A 300 ( 3.8A)NAD A 300 (-3.6A)NAD A 300 (-4.6A)None | 0.95A | 3uboB-5t5qA:6.7 | 3uboB-5t5qA:23.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tt0 | OXIDOREDUCTASE,SHORT CHAINDEHYDROGENASE/REDUCTASE FAMILY (Burkholderiathailandensis) |
PF13561(adh_short_C2) | 4 | SER A 133ILE A 16TYR A 145GLY A 176 | EDO A 310 ( 4.0A)NoneEDO A 310 (-4.2A)EDO A 309 ( 4.1A) | 1.01A | 3uboB-5tt0A:6.4 | 3uboB-5tt0A:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u2w | SHORT CHAINDEHYDROGENASE (Burkholderiacenocepacia) |
PF00106(adh_short) | 4 | SER A 141ILE A 18TYR A 155GLY A 186 | IMD A 304 (-3.4A)NAP A 301 (-4.0A)IMD A 304 ( 4.3A)NAP A 301 (-4.7A) | 1.01A | 3uboB-5u2wA:7.6 | 3uboB-5u2wA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u9p | GLUCONATE5-DEHYDROGENASE (Burkholderiacenocepacia) |
PF13561(adh_short_C2) | 4 | SER A 148ILE A 24TYR A 161GLY A 192 | TLA A 302 (-2.9A)NAP A 301 (-3.9A)TLA A 302 ( 4.0A)None | 0.90A | 3uboB-5u9pA:5.7 | 3uboB-5u9pA:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5unl | 3-KETOACYL-ACPREDUCTASE (Burkholderiamultivorans) |
PF13561(adh_short_C2) | 4 | SER A 148ILE A 24TYR A 161GLY A 192 | NO3 A 306 ( 4.5A)NoneNoneNone | 1.04A | 3uboB-5unlA:5.7 | 3uboB-5unlA:25.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vn2 | 3-OXOACYL-(ACYL-CARRIER PROTEIN)REDUCTASE (Brucellamelitensis) |
PF13561(adh_short_C2) | 4 | SER A 147ILE A 143TYR A 158GLY A 189 | ACT A 302 (-3.3A)NAD A 301 (-4.7A)ACT A 302 ( 4.2A)NAD A 301 ( 4.8A) | 0.91A | 3uboB-5vn2A:6.5 | 3uboB-5vn2A:24.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xww | AMPHB (Streptomycesnodosus) |
no annotation | 4 | SER A 354ILE A 230TYR A 367GLY A 394 | 8H6 A 502 ( 3.2A)NAP A 501 (-3.9A)NAP A 501 ( 4.5A)NAP A 501 (-4.9A) | 0.92A | 3uboB-5xwwA:4.8 | 3uboB-5xwwA:11.01 |