SIMILAR PATTERNS OF AMINO ACIDS FOR 3UA5_B_06XB501

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cen CELLULASE CELC

(Ruminiclostridium
thermocellum) 		PF00150
(Cellulase) 		4 ILE A  29
ILE A  14
GLU A  76
LEU A  85
 None
 0.85A 3ua5B-1cenA:
0.0		 3ua5B-1cenA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gll GLYCEROL KINASE

(Escherichia
coli) 		no annotation 4 ILE Y  74
ILE Y 229
SER Y  29
GLU Y  62
 None
 0.85A 3ua5B-1gllY:
0.0		 3ua5B-1gllY:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hzf COMPLEMENT FACTOR
C4A

(Homo sapiens) 		PF07678
(A2M_comp)
PF10569
(Thiol-ester_cl) 		4 ILE A1288
ILE A1128
SER A1294
LEU A1069
 None
 0.73A 3ua5B-1hzfA:
0.0		 3ua5B-1hzfA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mqs INTEGRAL MEMBRANE
PROTEIN SED5
SLY1 PROTEIN

(Saccharomyces
cerevisiae) 		PF00995
(Sec1)
PF11416
(Syntaxin-5_N) 		4 ILE A 153
ILE A 112
SER B  13
LEU A 132
 None
 0.86A 3ua5B-1mqsA:
0.0		 3ua5B-1mqsA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wu7 HISTIDYL-TRNA
SYNTHETASE

(Thermoplasma
acidophilum) 		PF03129
(HGTP_anticodon)
PF13393
(tRNA-synt_His) 		4 ILE A 337
ILE A 343
LEU A 414
VAL A 417
 None
 0.74A 3ua5B-1wu7A:
undetectable		 3ua5B-1wu7A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xiq NUCLEOSIDE
DIPHOSPHATE KINASE B

(Plasmodium
falciparum) 		PF00334
(NDK) 		4 ILE A 129
THR A  41
LEU A  38
VAL A  70
 None
 0.77A 3ua5B-1xiqA:
undetectable		 3ua5B-1xiqA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xty PEPTIDYL-TRNA
HYDROLASE

(Sulfolobus
solfataricus) 		PF01981
(PTH2) 		4 ILE A 102
SER A  63
LEU A 117
VAL A  61
 None
 0.84A 3ua5B-1xtyA:
undetectable		 3ua5B-1xtyA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a0j PTS SYSTEM, NITROGEN
REGULATORY IIA
PROTEIN

(Neisseria
meningitidis) 		PF00359
(PTS_EIIA_2) 		4 ILE A 100
SER A  21
GLU A  27
VAL A  19
 None
 0.83A 3ua5B-2a0jA:
undetectable		 3ua5B-2a0jA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a0j PTS SYSTEM, NITROGEN
REGULATORY IIA
PROTEIN

(Neisseria
meningitidis) 		PF00359
(PTS_EIIA_2) 		4 ILE A 102
SER A  21
GLU A  27
VAL A  19
 None
 0.82A 3ua5B-2a0jA:
undetectable		 3ua5B-2a0jA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN

(Cryptosporidium
parvum) 		PF08603
(CAP_C) 		4 ILE A  85
ILE A  94
GLU A  68
VAL A  45
 None
 0.80A 3ua5B-2b0rA:
undetectable		 3ua5B-2b0rA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dby GTP-BINDING PROTEIN

(Thermus
thermophilus) 		PF01926
(MMR_HSR1)
PF06071
(YchF-GTPase_C) 		4 ILE A 362
GLU A 355
THR A 304
LEU A 285
 None
 0.65A 3ua5B-2dbyA:
undetectable		 3ua5B-2dbyA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gdu SUCROSE
PHOSPHORYLASE

(Bifidobacterium
adolescentis) 		PF00128
(Alpha-amylase)
PF09244
(DUF1964) 		4 ILE A 131
THR A 165
LEU A 113
VAL A 118
 None
 0.84A 3ua5B-2gduA:
undetectable		 3ua5B-2gduA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI

(Bauhinia
bauhinioides) 		PF00197
(Kunitz_legume) 		4 ILE A 122
GLU A  85
THR A 102
VAL A  44
 None
 0.77A 3ua5B-2gzbA:
undetectable		 3ua5B-2gzbA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h0q SUPPRESSOR OF T-CELL
RECEPTOR SIGNALING 1

(Mus musculus) 		PF00300
(His_Phos_1) 		4 ILE A 524
SER A 458
GLU A 490
LEU A 500
 None
 0.80A 3ua5B-2h0qA:
undetectable		 3ua5B-2h0qA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ha8 TAR (HIV-1) RNA LOOP
BINDING PROTEIN

(Homo sapiens) 		PF00588
(SpoU_methylase) 		4 ILE A 135
SER A  32
LEU A 125
VAL A  30
 None
 0.88A 3ua5B-2ha8A:
undetectable		 3ua5B-2ha8A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hl9 UBIQUITIN-LIKE-SPECI
FIC PROTEASE 1

(Saccharomyces
cerevisiae) 		PF02902
(Peptidase_C48) 		4 ILE A 527
ILE A 504
GLU A 554
LEU A 479
 None
 0.81A 3ua5B-2hl9A:
undetectable		 3ua5B-2hl9A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i6b ADENOSINE KINASE

(Homo sapiens) 		PF00294
(PfkB) 		4 ILE A 192
SER A 308
GLU A 318
THR A 317
 None
 0.87A 3ua5B-2i6bA:
undetectable		 3ua5B-2i6bA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jac GLUTAREDOXIN-1

(Saccharomyces
cerevisiae) 		PF00462
(Glutaredoxin) 		4 ILE A  85
GLU A  18
LEU A 104
VAL A  43
 None
 0.88A 3ua5B-2jacA:
undetectable		 3ua5B-2jacA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jad YELLOW FLUORESCENT
PROTEIN GLUTAREDOXIN
FUSION PROTEIN

(Aequorea
victoria;
Saccharomyces
cerevisiae) 		PF00462
(Glutaredoxin)
PF01353
(GFP) 		4 ILE A 331
GLU A 264
LEU A 350
VAL A 289
 None
 0.82A 3ua5B-2jadA:
undetectable		 3ua5B-2jadA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mew 30S RIBOSOMAL
PROTEIN S10

(Thermotoga sp.
RQ2) 		PF00338
(Ribosomal_S10) 		4 ILE A  26
ILE A  56
GLU A  79
LEU A  53
 None
 0.88A 3ua5B-2mewA:
undetectable		 3ua5B-2mewA:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pz0 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE

(Caldanaerobacter
subterraneus) 		PF03009
(GDPD) 		4 ILE A  29
ILE A 109
GLU A  44
VAL A  57
 None
None
CA  A 501 ( 2.9A)
None
 0.84A 3ua5B-2pz0A:
undetectable		 3ua5B-2pz0A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q49 PROBABLE
N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE

(Arabidopsis
thaliana) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 ILE A 228
ILE A 259
GLU A 184
LEU A 176
 None
 0.82A 3ua5B-2q49A:
undetectable		 3ua5B-2q49A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v73 PUTATIVE
EXO-ALPHA-SIALIDASE

(Clostridium
perfringens) 		PF02973
(Sialidase) 		4 ILE A  40
ILE A 110
SER A  53
GLU A  79
 None
None
None
SIA  A1190 (-3.1A)
 0.59A 3ua5B-2v73A:
undetectable		 3ua5B-2v73A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vx4 CELLVIBRIO JAPONICUS
MANNANASE CJMAN26C

(Cellvibrio
japonicus) 		PF02156
(Glyco_hydro_26) 		4 ILE A 260
ILE A 333
LEU A  81
VAL A 150
 None
 0.86A 3ua5B-2vx4A:
undetectable		 3ua5B-2vx4A:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xsz RUVB-LIKE 1

(Homo sapiens) 		PF06068
(TIP49) 		4 ILE A 239
ILE A 272
GLU A  68
LEU A  38
 None
 0.65A 3ua5B-2xszA:
undetectable		 3ua5B-2xszA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ycb CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR

(Methanothermobacter
thermautotrophicus) 		PF07521
(RMMBL)
PF10996
(Beta-Casp)
PF16661
(Lactamase_B_6)
PF17214
(KH_7) 		4 ILE A 437
ILE A 411
LEU A 424
VAL A 427
 None
 0.79A 3ua5B-2ycbA:
undetectable		 3ua5B-2ycbA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b6n 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE

(Plasmodium
vivax) 		PF02542
(YgbB) 		4 ILE A  68
ILE A 133
SER A 145
VAL A 155
 None
 0.81A 3ua5B-3b6nA:
undetectable		 3ua5B-3b6nA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ff4 UNCHARACTERIZED
PROTEIN

(Cytophaga
hutchinsonii) 		PF13380
(CoA_binding_2) 		4 ILE A  97
ILE A 103
SER A  70
LEU A  61
 None
 0.88A 3ua5B-3ff4A:
undetectable		 3ua5B-3ff4A:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gg9 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
OXIDOREDUCTASE
PROTEIN

(Ralstonia
solanacearum) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 ILE A  84
THR A  44
LEU A  51
VAL A  55
 None
 0.70A 3ua5B-3gg9A:
undetectable		 3ua5B-3gg9A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ghf SEPTUM
SITE-DETERMINING
PROTEIN MINC

(Salmonella
enterica) 		PF05209
(MinC_N) 		4 ILE A  90
ILE A  75
GLU A  63
VAL A  59
 None
None
CIT  A 201 (-3.6A)
CIT  A 201 (-3.8A)
 0.83A 3ua5B-3ghfA:
undetectable		 3ua5B-3ghfA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h4m PROTEASOME-ACTIVATIN
G NUCLEOTIDASE

(Methanocaldococcus
jannaschii) 		PF00004
(AAA) 		4 ILE A 172
GLU A 181
LEU A 209
VAL A 338
 ADP  A 439 (-4.7A)
None
None
None
 0.69A 3ua5B-3h4mA:
undetectable		 3ua5B-3h4mA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j7a 40S RIBOSOMAL
PROTEIN US5

(Plasmodium
falciparum) 		PF00333
(Ribosomal_S5)
PF03719
(Ribosomal_S5_C) 		4 ILE G  75
GLU G  61
LEU G  47
VAL G  51
 None
 0.76A 3ua5B-3j7aG:
undetectable		 3ua5B-3j7aG:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR CWF5

(Schizosaccharomyces
pombe) 		PF08082
(PRO8NT)
PF08083
(PROCN)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV) 		4 ILE a  69
ILE a  93
SER a  48
THR a 108
 None
 0.76A 3ua5B-3jb9a:
undetectable		 3ua5B-3jb9a:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jxv 70 KDA
PEPTIDYL-PROLYL
ISOMERASE

(Triticum
aestivum) 		PF00254
(FKBP_C) 		4 ILE A 331
ILE A 300
SER A 372
VAL A 368
 None
 0.88A 3ua5B-3jxvA:
undetectable		 3ua5B-3jxvA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE

(Agrobacterium
fabrum) 		PF03009
(GDPD) 		4 SER A  17
GLU A  34
LEU A  37
VAL A  47
 None
FE  A 250 ( 2.6A)
None
None
 0.88A 3ua5B-3ks5A:
undetectable		 3ua5B-3ks5A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3la6 TYROSINE-PROTEIN
KINASE WZC

(Escherichia
coli) 		PF13614
(AAA_31) 		4 ILE A 641
ILE A 607
GLU A 627
LEU A 586
 None
 0.88A 3ua5B-3la6A:
undetectable		 3ua5B-3la6A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mjd OROTATE
PHOSPHORIBOSYLTRANSF
ERASE

(Francisella
tularensis) 		PF00156
(Pribosyltran) 		4 ILE A 142
SER A 167
LEU A 147
VAL A 174
 None
 0.83A 3ua5B-3mjdA:
undetectable		 3ua5B-3mjdA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mzb NICKEL-BINDING
PERIPLASMIC PROTEIN

(Escherichia
coli) 		PF00496
(SBP_bac_5) 		4 ILE A 467
GLU A 358
LEU A 344
VAL A 371
 None
 0.78A 3ua5B-3mzbA:
undetectable		 3ua5B-3mzbA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nks PROTOPORPHYRINOGEN
OXIDASE

(Homo sapiens) 		PF01593
(Amino_oxidase) 		4 ILE A  61
ILE A  43
GLU A  83
VAL A  75
 None
 0.87A 3ua5B-3nksA:
undetectable		 3ua5B-3nksA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nng UNCHARACTERIZED
PROTEIN

(Bacteroides
fragilis) 		PF00754
(F5_F8_type_C) 		4 ILE A 331
GLU A 335
LEU A 245
VAL A 312
 None
 0.83A 3ua5B-3nngA:
undetectable		 3ua5B-3nngA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o8l 6-PHOSPHOFRUCTOKINAS
E, MUSCLE TYPE

(Oryctolagus
cuniculus) 		PF00365
(PFK) 		4 ILE A 259
GLU A 206
THR A 294
VAL A 279
 None
 0.81A 3ua5B-3o8lA:
undetectable		 3ua5B-3o8lA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pet PUTATIVE ADHESIN

(Bacteroides
fragilis) 		PF10988
(DUF2807) 		4 ILE A 116
SER A 159
LEU A 167
VAL A 165
 None
 0.80A 3ua5B-3petA:
undetectable		 3ua5B-3petA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r1x 2-OXO-3-DEOXYGALACTO
NATE KINASE

(Klebsiella
pneumoniae) 		PF05035
(DGOK) 		4 ILE A  99
ILE A   6
GLU A  49
LEU A  15
 None
 0.68A 3ua5B-3r1xA:
undetectable		 3ua5B-3r1xA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ry7 RIBOKINASE

(Staphylococcus
aureus) 		PF00294
(PfkB) 		4 ILE A 183
SER A 203
GLU A 187
THR A 222
 None
 0.86A 3ua5B-3ry7A:
0.2		 3ua5B-3ry7A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t3c HIV-1 PROTEASE

(Human
immunodeficiency
virus 1) 		PF00077
(RVP) 		4 ILE A  64
ILE A  93
LEU A  24
VAL A  22
 None
None
None
SO4  A 101 (-4.8A)
 0.87A 3ua5B-3t3cA:
undetectable		 3ua5B-3t3cA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t7b ACETYLGLUTAMATE
KINASE

(Yersinia pestis) 		PF00696
(AA_kinase) 		4 ILE A 147
ILE A  72
GLU A 152
VAL A 111
 None
 0.86A 3ua5B-3t7bA:
undetectable		 3ua5B-3t7bA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tts BETA-GALACTOSIDASE

(Bacillus
circulans) 		PF02449
(Glyco_hydro_42)
PF08532
(Glyco_hydro_42M)
PF08533
(Glyco_hydro_42C) 		4 ILE A   9
GLU A 378
LEU A 653
VAL A 669
 None
 0.86A 3ua5B-3ttsA:
undetectable		 3ua5B-3ttsA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ujz METALLOPROTEASE STCE

(Escherichia
coli) 		PF10462
(Peptidase_M66) 		4 ILE A 834
SER A 843
LEU A 851
VAL A 849
 None
 0.83A 3ua5B-3ujzA:
undetectable		 3ua5B-3ujzA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wo6 MEMBRANE PROTEIN
INSERTASE YIDC 2

(Bacillus
halodurans) 		PF02096
(60KD_IMP) 		4 ILE A 249
ILE A  65
LEU A 176
VAL A 179
 None
 0.85A 3ua5B-3wo6A:
0.6		 3ua5B-3wo6A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zpc RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBD

(Acinetobacter
baumannii) 		PF00383
(dCMP_cyt_deam_1)
PF01872
(RibD_C) 		4 ILE A 241
ILE A 198
GLU A 257
VAL A 263
 None
 0.83A 3ua5B-3zpcA:
undetectable		 3ua5B-3zpcA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bg2 PATF

(Prochloron
didemni) 		no annotation 4 ILE A 141
SER A 103
LEU A 191
VAL A 189
 None
 0.85A 3ua5B-4bg2A:
undetectable		 3ua5B-4bg2A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bkw ZINC FINGER FYVE
DOMAIN-CONTAINING
PROTEIN 9

(Homo sapiens) 		PF11979
(DUF3480) 		4 ILE A1417
ILE A1283
THR A1367
LEU A1317
 None
 0.86A 3ua5B-4bkwA:
undetectable		 3ua5B-4bkwA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c23 L-FUCULOSE KINASE
FUCK

(Streptococcus
pneumoniae) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 ILE A 297
ILE A 331
SER A 342
GLU A 350
 None
 0.86A 3ua5B-4c23A:
undetectable		 3ua5B-4c23A:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cze ROD
SHAPE-DETERMINING
PROTEIN MREB

(Caulobacter
vibrioides) 		PF06723
(MreB_Mbl) 		4 ILE A  89
ILE A  79
LEU A 137
VAL A 135
 None
 0.88A 3ua5B-4czeA:
undetectable		 3ua5B-4czeA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e6w CLBP PEPTIDASE

(Escherichia
coli) 		PF00144
(Beta-lactamase) 		4 ILE A 120
SER A 313
LEU A 114
VAL A 105
 None
 0.88A 3ua5B-4e6wA:
undetectable		 3ua5B-4e6wA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ekx 14L PROTEIN

(Tanapox virus) 		no annotation 4 ILE C 129
ILE C  29
GLU C 107
LEU C  97
 None
 0.88A 3ua5B-4ekxC:
undetectable		 3ua5B-4ekxC:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ep6 CYTOCHROME P450-LIKE
PROTEIN XPLA

(Rhodococcus
rhodochrous) 		PF00067
(p450) 		4 ILE A 404
GLU A 522
LEU A 276
VAL A 272
 None
 0.86A 3ua5B-4ep6A:
30.7		 3ua5B-4ep6A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ep6 CYTOCHROME P450-LIKE
PROTEIN XPLA

(Rhodococcus
rhodochrous) 		PF00067
(p450) 		4 ILE A 527
GLU A 522
LEU A 276
VAL A 272
 None
 0.74A 3ua5B-4ep6A:
30.7		 3ua5B-4ep6A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fye SIDF, INHIBITOR OF
GROWTH FAMILY,
MEMBER 3

(Legionella
pneumophila) 		no annotation 4 ILE A   8
ILE A 204
LEU A  16
VAL A 259
 None
 0.79A 3ua5B-4fyeA:
undetectable		 3ua5B-4fyeA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hns CHEMOTAXIS PROTEIN
CHEY

(Vibrio cholerae) 		PF00072
(Response_reg) 		4 ILE A 110
ILE A 126
LEU A  28
VAL A  24
 None
 0.88A 3ua5B-4hnsA:
undetectable		 3ua5B-4hnsA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i34 ATP-DEPENDENT CLP
PROTEASE ATP-BINDING
SUBUNIT CLPX

(Escherichia
coli) 		PF07724
(AAA_2)
PF10431
(ClpB_D2-small) 		4 ILE A 358
SER A 401
LEU A 348
VAL A 397
 None
 0.79A 3ua5B-4i34A:
undetectable		 3ua5B-4i34A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kha SPT16M-HISTONE H2B
1.1 CHIMERA

(Chaetomium
thermophilum;
Xenopus laevis) 		PF00125
(Histone)
PF08512
(Rtt106)
PF08644
(SPT16) 		4 ILE A 832
ILE A 850
LEU A 901
VAL A 897
 None
 0.72A 3ua5B-4khaA:
undetectable		 3ua5B-4khaA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kho UNCHARACTERIZED
PROTEIN SPT16M

(Chaetomium
thermophilum) 		PF08512
(Rtt106)
PF08644
(SPT16) 		4 ILE A 834
ILE A 852
LEU A 903
VAL A 899
 None
 0.78A 3ua5B-4khoA:
undetectable		 3ua5B-4khoA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ldq METHYLTHIORIBOSE-1-P
HOSPHATE ISOMERASE

(Homo sapiens) 		PF01008
(IF-2B) 		4 ILE A  51
SER A  32
GLU A  38
VAL A  30
 None
 0.88A 3ua5B-4ldqA:
1.7		 3ua5B-4ldqA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4le5 S-ADENOSYLMETHIONINE
SYNTHETASE

(Campylobacter
jejuni) 		PF00438
(S-AdoMet_synt_N)
PF02772
(S-AdoMet_synt_M)
PF02773
(S-AdoMet_synt_C) 		4 ILE A 217
ILE A 191
SER A 197
GLU A   7
 None
 0.78A 3ua5B-4le5A:
undetectable		 3ua5B-4le5A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n18 D-ISOMER SPECIFIC
2-HYDROXYACID
DEHYDROGENASE FAMILY
PROTEIN

(Klebsiella
pneumoniae) 		PF02826
(2-Hacid_dh_C) 		4 ILE A  19
ILE A   6
GLU A 289
VAL A  88
 None
 0.76A 3ua5B-4n18A:
undetectable		 3ua5B-4n18A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nu2 ANTIFREEZE PROTEIN

(Flavobacterium
frigoris) 		PF11999
(DUF3494) 		4 ILE A 241
SER A  77
LEU A 267
VAL A 265
 None
 0.68A 3ua5B-4nu2A:
undetectable		 3ua5B-4nu2A:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nu3 ICE-BINDING PROTEIN

(Flavobacterium
frigoris) 		PF11999
(DUF3494) 		4 ILE A 221
SER A  50
LEU A 247
VAL A 245
 None
 0.63A 3ua5B-4nu3A:
undetectable		 3ua5B-4nu3A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o00 TITIN

(Homo sapiens) 		PF00041
(fn3) 		4 ILE A  42
SER A  14
LEU A  70
VAL A  22
 None
 0.87A 3ua5B-4o00A:
undetectable		 3ua5B-4o00A:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4om9 SERINE PROTEASE PET

(Escherichia
coli) 		PF02395
(Peptidase_S6) 		4 ILE A 263
ILE A 275
LEU A 305
VAL A 326
 None
 0.81A 3ua5B-4om9A:
undetectable		 3ua5B-4om9A:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pwo DSBA

(Corynebacterium
diphtheriae) 		PF13462
(Thioredoxin_4) 		4 ILE A 258
GLU A 272
LEU A 140
VAL A 150
 None
 0.81A 3ua5B-4pwoA:
undetectable		 3ua5B-4pwoA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q7q LIPOLYTIC PROTEIN
G-D-S-L FAMILY

(Chitinophaga
pinensis) 		PF13472
(Lipase_GDSL_2) 		4 ILE A  31
ILE A 143
SER A 256
LEU A 200
 None
 0.69A 3ua5B-4q7qA:
undetectable		 3ua5B-4q7qA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qxa RAS-RELATED PROTEIN
RAB-9A

(Mus musculus) 		PF00071
(Ras) 		4 ILE A 172
ILE A  10
LEU A  49
VAL A  51
 None
 0.85A 3ua5B-4qxaA:
undetectable		 3ua5B-4qxaA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r04 TOXIN A

(Clostridioides
difficile) 		PF11713
(Peptidase_C80)
PF12918
(TcdB_N)
PF12919
(TcdA_TcdB)
PF12920
(TcdA_TcdB_pore) 		4 ILE A 739
ILE A 677
SER A 736
THR A 728
 None
 0.86A 3ua5B-4r04A:
undetectable		 3ua5B-4r04A:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r37 PUTATIVE
ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE

(Bacteroides
fragilis) 		PF00132
(Hexapep)
PF13720
(Acetyltransf_11) 		4 ILE A 242
ILE A 190
GLU A 203
VAL A 233
 None
 0.85A 3ua5B-4r37A:
undetectable		 3ua5B-4r37A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zu9 ELONGATION FACTOR
SELB

(Aquifex
aeolicus) 		PF00009
(GTP_EFTU)
PF09107
(SelB-wing_3) 		4 ILE A  48
ILE A  20
SER A 163
THR A 116
 None
 0.88A 3ua5B-4zu9A:
undetectable		 3ua5B-4zu9A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b37 TRYPTOPHAN
DEHYDROGENASE

(Nostoc
punctiforme) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		4 ILE A 154
GLU A 190
LEU A 195
VAL A 193
 None
 0.65A 3ua5B-5b37A:
undetectable		 3ua5B-5b37A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cdh MAJOR ACID
PHOSPHATASE

(Legionella
pneumophila) 		PF00328
(His_Phos_2) 		4 ILE A 258
ILE A 321
SER A 252
LEU A 346
 None
 0.76A 3ua5B-5cdhA:
undetectable		 3ua5B-5cdhA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5che GLUTAMYL-TRNA
REDUCTASE-BINDING
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF10615
(DUF2470) 		4 ILE C 219
ILE C 261
LEU C 229
VAL C 233
 None
 0.86A 3ua5B-5cheC:
undetectable		 3ua5B-5cheC:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5doo PROTEIN LYSINE
METHYLTRANSFERASE 2

(Rickettsia
typhi) 		PF10119
(MethyTransf_Reg)
PF13847
(Methyltransf_31) 		4 ILE A 462
ILE A 469
GLU A 524
LEU A 532
 None
 0.70A 3ua5B-5dooA:
0.9		 3ua5B-5dooA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dzx PROTOCADHERIN BETA 6

(Mus musculus) 		PF00028
(Cadherin)
PF08266
(Cadherin_2) 		4 ILE A 272
THR A 283
LEU A 278
VAL A 223
 None
 0.88A 3ua5B-5dzxA:
undetectable		 3ua5B-5dzxA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fre EXO-ALPHA-SIALIDASE

(Clostridium
perfringens) 		PF02973
(Sialidase) 		4 ILE A  35
ILE A 111
SER A  48
GLU A  74
 None
None
None
SIA  A 201 (-3.1A)
 0.64A 3ua5B-5freA:
undetectable		 3ua5B-5freA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g4q DNA POLYMERASE III
SUBUNIT BETA

(Helicobacter
pylori) 		PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3) 		4 ILE A  98
ILE A  70
LEU A  42
VAL A   5
 None
 0.81A 3ua5B-5g4qA:
undetectable		 3ua5B-5g4qA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gin 50S RIBOSOMAL
PROTEIN L7AE

(Sulfolobus
solfataricus) 		PF01248
(Ribosomal_L7Ae) 		4 ILE C  55
ILE C  35
SER C  85
GLU C  91
 None
 0.77A 3ua5B-5ginC:
undetectable		 3ua5B-5ginC:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ik8 LAMININ SUBUNIT
ALPHA-2

(Mus musculus) 		PF00054
(Laminin_G_1)
PF02210
(Laminin_G_2) 		4 ILE A3084
ILE A2986
LEU A3089
VAL A3099
 None
 0.83A 3ua5B-5ik8A:
undetectable		 3ua5B-5ik8A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5il7 RAB FAMILY PROTEIN

(Chlorobaculum
tepidum) 		PF12799
(LRR_4)
PF13516
(LRR_6) 		4 ILE A 408
ILE A 364
LEU A 415
VAL A 423
 None
 0.87A 3ua5B-5il7A:
undetectable		 3ua5B-5il7A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jpn COMPLEMENT C4-A

(Homo sapiens) 		PF00207
(A2M)
PF01821
(ANATO)
PF07678
(A2M_comp)
PF10569
(Thiol-ester_cl) 		4 ILE B1307
ILE B1147
SER B1313
LEU B1088
 None
 0.71A 3ua5B-5jpnB:
1.7		 3ua5B-5jpnB:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jyu TWO-COMPONENT SENSOR
HISTIDINE KINASE

(Thermosynechococcus
elongatus) 		no annotation 4 ILE A 704
THR A 625
LEU A 618
VAL A 640
 None
 0.78A 3ua5B-5jyuA:
undetectable		 3ua5B-5jyuA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m5e INTERLEUKIN-2

(Homo sapiens) 		PF00715
(IL2) 		4 ILE D  86
ILE D  24
LEU D  17
VAL D  93
 None
 0.80A 3ua5B-5m5eD:
undetectable		 3ua5B-5m5eD:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n0c TETANUS TOXIN

(Clostridium
tetani) 		PF01742
(Peptidase_M27)
PF07951
(Toxin_R_bind_C)
PF07952
(Toxin_trans)
PF07953
(Toxin_R_bind_N) 		4 ILE A 704
GLU A 713
LEU A 688
VAL A 494
 None
 0.85A 3ua5B-5n0cA:
undetectable		 3ua5B-5n0cA:
16.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o4g RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-2

(Homo sapiens) 		no annotation 4 ILE C 339
SER C 391
GLU C 357
LEU C 323
 None
 0.86A 3ua5B-5o4gC:
undetectable		 3ua5B-5o4gC:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uqd DUMPY: SHORTER THAN
WILD-TYPE

(Caenorhabditis
elegans) 		no annotation 4 ILE A1592
GLU A1527
LEU A1564
VAL A1559
 None
 0.82A 3ua5B-5uqdA:
undetectable		 3ua5B-5uqdA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v41 POLYKETIDE SYNTHASE
PKS13 (TERMINATION
POLYKETIDE SYNTHASE)

(Mycobacterium
tuberculosis) 		PF00975
(Thioesterase) 		4 ILE A1544
ILE A1648
LEU A1558
VAL A1556
 None
 0.87A 3ua5B-5v41A:
undetectable		 3ua5B-5v41A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vgc NLEG5-1 EFFECTOR

(Enterobacteria
phage YYZ-2008) 		no annotation 4 ILE A  27
ILE A  19
LEU A  40
VAL A  45
 None
 0.84A 3ua5B-5vgcA:
undetectable		 3ua5B-5vgcA:
10.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5wbg CYTOCHROME P450 2B6

(Homo sapiens) 		no annotation 4 ILE A 114
THR A 302
LEU A 363
VAL A 477
 9ZJ  A 502 ( 3.6A)
9ZJ  A 502 ( 3.9A)
HEM  A 501 (-4.3A)
None
 0.66A 3ua5B-5wbgA:
54.8		 3ua5B-5wbgA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK

(Campylobacter
jejuni) 		no annotation 4 ILE A 451
ILE A 389
SER A 348
LEU A 360
 None
 0.88A 3ua5B-5xbjA:
0.0		 3ua5B-5xbjA:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xog RNA POLYMERASE II
THIRD LARGEST
SUBUNIT B44, PART OF
CENTRAL CORE

(Komagataella
phaffii) 		PF01000
(RNA_pol_A_bac)
PF01193
(RNA_pol_L) 		4 ILE C 155
SER C 117
LEU C 147
VAL C 113
 None
 0.82A 3ua5B-5xogC:
undetectable		 3ua5B-5xogC:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b3n NLEG5-1

(Escherichia
coli) 		no annotation 4 ILE A  27
ILE A  19
LEU A  40
VAL A  45
 None
 0.87A 3ua5B-6b3nA:
undetectable		 3ua5B-6b3nA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6el1 YAXB

(Yersinia
enterocolitica) 		no annotation 4 ILE O 145
ILE O 285
GLU O 156
VAL O  40
 None
 0.88A 3ua5B-6el1O:
2.5		 3ua5B-6el1O:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6etz BETA-GALACTOSIDASE

(Arthrobacter
sp. 32cB) 		no annotation 4 ILE A 937
GLU A 867
LEU A 870
VAL A 753
 None
 0.73A 3ua5B-6etzA:
undetectable		 3ua5B-6etzA:
11.61