SIMILAR PATTERNS OF AMINO ACIDS FOR 3U9F_K_CLMK221_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d4e FLAVOCYTOCHROME C
FUMARATE REDUCTASE

(Shewanella
oneidensis) 		PF00890
(FAD_binding_2)
PF14537
(Cytochrom_c3_2) 		3 PHE A  90
CYH A  84
HIS A  88
 HEM  A 601 (-4.3A)
HEM  A 601 (-1.9A)
HEM  A 601 (-3.2A)
 1.16A 3u9fL-1d4eA:
0.0		 3u9fL-1d4eA:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e96 NEUTROPHIL CYTOSOL
FACTOR 2 (NCF-2) TPR
DOMAIN, RESIDUES
1-203

(Homo sapiens) 		PF07719
(TPR_2)
PF13181
(TPR_8) 		3 PHE B 119
CYH B 121
HIS B 156
 None
 1.32A 3u9fL-1e96B:
undetectable		 3u9fL-1e96B:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f8f BENZYL ALCOHOL
DEHYDROGENASE

(Acinetobacter
calcoaceticus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		3 PHE A 140
CYH A 173
HIS A  65
 EOH  A 374 (-4.6A)
ZN  A 372 ( 2.1A)
ZN  A 372 (-3.4A)
 1.10A 3u9fL-1f8fA:
0.0		 3u9fL-1f8fA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fi4 MEVALONATE
5-DIPHOSPHATE
DECARBOXYLASE

(Saccharomyces
cerevisiae) 		PF00288
(GHMP_kinases_N) 		3 PHE A 260
CYH A 264
HIS A 261
 None
 0.87A 3u9fL-1fi4A:
0.0		 3u9fL-1fi4A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gyc LACCASE 2

(Trametes
versicolor) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 PHE A 463
CYH A 453
HIS A 395
 CU  A1503 (-4.8A)
CU  A1503 (-2.1A)
CU  A1503 (-3.1A)
 1.31A 3u9fL-1gycA:
0.0		 3u9fL-1gycA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jov HI1317

(Haemophilus
influenzae) 		PF01263
(Aldose_epim) 		3 PHE A  80
CYH A  76
HIS A  88
 None
None
SO4  A 280 ( 4.7A)
 0.94A 3u9fL-1jovA:
0.0		 3u9fL-1jovA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1khu SMAD1

(Homo sapiens) 		PF03166
(MH2) 		3 PHE A 366
CYH A 360
HIS A 364
 None
 1.29A 3u9fL-1khuA:
0.0		 3u9fL-1khuA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kya LACCASE

(Trametes
versicolor) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 PHE A 463
CYH A 453
HIS A 395
 CU  A 500 (-4.8A)
CU  A 500 (-2.2A)
CU  A 500 (-3.4A)
 1.29A 3u9fL-1kyaA:
0.0		 3u9fL-1kyaA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lpv DOUBLESEX PROTEIN

(Drosophila
melanogaster) 		PF00751
(DM) 		3 PHE A  31
CYH A  34
HIS A  16
 None
ZN  A  53 (-2.2A)
ZN  A  53 (-3.3A)
 1.26A 3u9fL-1lpvA:
undetectable		 3u9fL-1lpvA:
10.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1pd5 CHLORAMPHENICOL
ACETYLTRANSFERASE

(Escherichia
coli) 		PF00302
(CAT) 		3 PHE A  25
CYH A  31
HIS A 193
 None
 0.20A 3u9fL-1pd5A:
34.4		 3u9fL-1pd5A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pss PHOTOSYNTHETIC
REACTION CENTER

(Rhodobacter
sphaeroides) 		PF00124
(Photo_RC) 		3 PHE L 167
CYH L 247
HIS L 173
 BCL  L   2 (-4.1A)
BCL  L   2 (-3.2A)
BCL  L   2 (-3.7A)
 1.30A 3u9fL-1pssL:
undetectable		 3u9fL-1pssL:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qo8 FLAVOCYTOCHROME C3
FUMARATE REDUCTASE

(Shewanella
frigidimarina) 		PF00890
(FAD_binding_2)
PF14537
(Cytochrom_c3_2) 		3 PHE A  85
CYH A  79
HIS A  83
 HEM  A 601 (-4.7A)
HEM  A 601 (-2.3A)
HEM  A 601 (-3.1A)
 1.16A 3u9fL-1qo8A:
0.0		 3u9fL-1qo8A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1siq GLUTARYL-COA
DEHYDROGENASE

(Homo sapiens) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		3 PHE A 263
CYH A 264
HIS A 359
 None
 1.34A 3u9fL-1siqA:
undetectable		 3u9fL-1siqA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x6h TRANSCRIPTIONAL
REPRESSOR CTCF

(Homo sapiens) 		PF00096
(zf-C2H2) 		3 PHE A  35
CYH A  18
HIS A  20
 None
ZN  A 201 (-2.3A)
None
 1.27A 3u9fL-1x6hA:
undetectable		 3u9fL-1x6hA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z01 2-OXO-1,2-DIHYDROQUI
NOLINE
8-MONOOXYGENASE,
OXYGENASE COMPONENT

(Pseudomonas
putida) 		PF00355
(Rieske)
PF11723
(Aromatic_hydrox) 		3 PHE A 110
CYH A  84
HIS A  86
 FES  A 500 (-4.1A)
FES  A 500 (-2.3A)
FES  A 500 (-3.2A)
 1.18A 3u9fL-1z01A:
undetectable		 3u9fL-1z01A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zhv HYPOTHETICAL PROTEIN
ATU0741

(Agrobacterium
fabrum) 		PF13840
(ACT_7) 		3 PHE A  34
CYH A  65
HIS A 104
 None
 1.22A 3u9fL-1zhvA:
undetectable		 3u9fL-1zhvA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ajh LEUCYL-TRNA
SYNTHETASE

(Escherichia
coli) 		PF13603
(tRNA-synt_1_2) 		3 PHE A 253
CYH A 256
HIS A 311
 None
 1.32A 3u9fL-2ajhA:
undetectable		 3u9fL-2ajhA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bd0 SEPIAPTERIN
REDUCTASE

(Chlorobaculum
tepidum) 		PF00106
(adh_short) 		3 PHE A 141
CYH A  89
HIS A 139
 None
 0.91A 3u9fL-2bd0A:
undetectable		 3u9fL-2bd0A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bsx PURINE NUCLEOSIDE
PHOSPHORYLASE

(Plasmodium
falciparum) 		PF01048
(PNP_UDP_1) 		3 PHE A  75
CYH A  71
HIS A  64
 None
 1.28A 3u9fL-2bsxA:
undetectable		 3u9fL-2bsxA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cs3 PROTEIN C14ORF4

(Homo sapiens) 		PF00097
(zf-C3HC4) 		3 PHE A  41
CYH A  33
HIS A  39
 None
ZN  A 400 (-2.3A)
ZN  A 400 (-3.1A)
 0.98A 3u9fL-2cs3A:
undetectable		 3u9fL-2cs3A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cs3 PROTEIN C14ORF4

(Homo sapiens) 		PF00097
(zf-C3HC4) 		3 PHE A  41
CYH A  61
HIS A  39
 None
ZN  A 400 (-2.3A)
ZN  A 400 (-3.1A)
 1.30A 3u9fL-2cs3A:
undetectable		 3u9fL-2cs3A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cy7 CYSTEINE PROTEASE
APG4B

(Homo sapiens) 		PF03416
(Peptidase_C54) 		3 PHE A  16
CYH A 306
HIS A 303
 None
 1.11A 3u9fL-2cy7A:
undetectable		 3u9fL-2cy7A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dlt MYOSIN BINDING
PROTEIN C, FAST-TYPE

(Mus musculus) 		PF07679
(I-set) 		3 PHE A  80
CYH A  30
HIS A  63
 None
 0.85A 3u9fL-2dltA:
undetectable		 3u9fL-2dltA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e6r JUMONJI/ARID
DOMAIN-CONTAINING
PROTEIN 1D

(Homo sapiens) 		PF00628
(PHD) 		3 PHE A  44
CYH A  45
HIS A  42
 None
ZN  A 201 (-2.2A)
ZN  A 201 (-2.9A)
 0.79A 3u9fL-2e6rA:
undetectable		 3u9fL-2e6rA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2he3 GLUTATHIONE
PEROXIDASE 2

(Homo sapiens) 		PF00255
(GSHPx) 		3 PHE A  66
CYH A 105
HIS A 113
 None
 1.35A 3u9fL-2he3A:
undetectable		 3u9fL-2he3A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hpi DNA POLYMERASE III
ALPHA SUBUNIT

(Thermus
aquaticus) 		PF02811
(PHP)
PF07733
(DNA_pol3_alpha)
PF14579
(HHH_6) 		3 PHE A 249
CYH A 246
HIS A 184
 None
 1.09A 3u9fL-2hpiA:
undetectable		 3u9fL-2hpiA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2htb PUTATIVE ENZYME
RELATED TO ALDOSE
1-EPIMERASE

(Salmonella
enterica) 		PF01263
(Aldose_epim) 		3 PHE A  84
CYH A  80
HIS A  95
 None
 0.86A 3u9fL-2htbA:
undetectable		 3u9fL-2htbA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j7j TRANSCRIPTION FACTOR
IIIA

(Xenopus laevis) 		PF00096
(zf-C2H2) 		3 PHE A   6
CYH A   4
HIS A   5
 None
ZN  A1086 (-2.2A)
None
 1.28A 3u9fL-2j7jA:
undetectable		 3u9fL-2j7jA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lxp E3 UBIQUITIN-PROTEIN
LIGASE AMFR

(Homo sapiens) 		PF13639
(zf-RING_2) 		3 PHE C 360
CYH C 375
HIS C 358
 None
ZN  C 901 (-2.2A)
ZN  C 901 (-2.9A)
 1.29A 3u9fL-2lxpC:
undetectable		 3u9fL-2lxpC:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mnz LYSINE-SPECIFIC
DEMETHYLASE 5B

(Homo sapiens) 		PF00628
(PHD) 		3 PHE A 337
CYH A 338
HIS A 335
 ZN  A 401 ( 4.8A)
ZN  A 401 (-2.3A)
ZN  A 401 (-3.1A)
 0.80A 3u9fL-2mnzA:
undetectable		 3u9fL-2mnzA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nm1 BOTULINUM NEUROTOXIN
TYPE B

(Clostridium
botulinum) 		PF07951
(Toxin_R_bind_C)
PF07953
(Toxin_R_bind_N) 		3 PHE A1243
CYH A1258
HIS A1241
 None
 1.28A 3u9fL-2nm1A:
undetectable		 3u9fL-2nm1A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oaj PROTEIN SNI1

(Saccharomyces
cerevisiae) 		PF08596
(Lgl_C) 		3 PHE A 418
CYH A 341
HIS A 422
 None
 0.95A 3u9fL-2oajA:
undetectable		 3u9fL-2oajA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oyo UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN

(Deinococcus
geothermalis) 		PF02627
(CMD) 		3 PHE A 172
CYH A  93
HIS A  97
 None
 1.30A 3u9fL-2oyoA:
undetectable		 3u9fL-2oyoA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ozu HISTONE
ACETYLTRANSFERASE
MYST3

(Homo sapiens) 		PF01853
(MOZ_SAS) 		3 PHE A 563
CYH A 626
HIS A 564
 None
 0.65A 3u9fL-2ozuA:
undetectable		 3u9fL-2ozuA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p0u STILBENECARBOXYLATE
SYNTHASE 2

(Marchantia
polymorpha) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		3 PHE A 391
CYH A 182
HIS A 321
 None
 1.31A 3u9fL-2p0uA:
undetectable		 3u9fL-2p0uA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pfx UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN

(Ruegeria sp.
TM1040) 		PF02627
(CMD) 		3 PHE A 167
CYH A  88
HIS A  92
 None
 1.33A 3u9fL-2pfxA:
undetectable		 3u9fL-2pfxA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qt6 LACCASE

(Lentinus
tigrinus) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 PHE A 462
CYH A 452
HIS A 394
 CU  A 499 (-4.9A)
CU  A 499 (-2.2A)
CU  A 499 (-3.1A)
 1.29A 3u9fL-2qt6A:
undetectable		 3u9fL-2qt6A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vpj KELCH-LIKE PROTEIN
12

(Homo sapiens) 		PF01344
(Kelch_1) 		3 PHE A 481
CYH A 511
HIS A 486
 None
 0.96A 3u9fL-2vpjA:
undetectable		 3u9fL-2vpjA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xyb LACCASE

(Trametes
cinnabarina) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 PHE A 337
CYH A 451
HIS A 456
 None
CU  A 501 (-2.2A)
CU  A 501 ( 3.1A)
 0.95A 3u9fL-2xybA:
undetectable		 3u9fL-2xybA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xyb LACCASE

(Trametes
cinnabarina) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 PHE A 461
CYH A 451
HIS A 395
 CU  A 501 ( 4.9A)
CU  A 501 (-2.2A)
CU  A 501 (-3.1A)
 1.31A 3u9fL-2xybA:
undetectable		 3u9fL-2xybA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ys2 CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX

(Homo sapiens) 		PF00779
(BTK) 		3 PHE A  25
CYH A  27
HIS A  16
 None
ZN  A 201 (-2.2A)
ZN  A 201 (-3.1A)
 1.08A 3u9fL-2ys2A:
undetectable		 3u9fL-2ys2A:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ysm MYELOID/LYMPHOID OR
MIXED-LINEAGE
LEUKEMIA PROTEIN 3
HOMOLOG

(Homo sapiens) 		PF00628
(PHD) 		3 PHE A  82
CYH A  83
HIS A  80
 ZN  A 701 ( 4.9A)
ZN  A 701 (-2.3A)
ZN  A 701 (-3.0A)
 0.90A 3u9fL-2ysmA:
undetectable		 3u9fL-2ysmA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yuz MYOSIN-BINDING
PROTEIN C, SLOW-TYPE

(Homo sapiens) 		PF07679
(I-set) 		3 PHE A  78
CYH A  29
HIS A  61
 None
 1.01A 3u9fL-2yuzA:
undetectable		 3u9fL-2yuzA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d4j DIPHOSPHOMEVALONATE
DECARBOXYLASE

(Homo sapiens) 		PF00288
(GHMP_kinases_N) 		3 PHE A 263
CYH A 267
HIS A 264
 None
 0.89A 3u9fL-3d4jA:
undetectable		 3u9fL-3d4jA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dit PROTEIN MOTHERS
AGAINST DPP

(Drosophila
melanogaster) 		PF03166
(MH2) 		3 PHE A 356
CYH A 350
HIS A 354
 None
 1.19A 3u9fL-3ditA:
undetectable		 3u9fL-3ditA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax) 		PF01048
(PNP_UDP_1) 		3 PHE A  76
CYH A  72
HIS A  65
 None
 1.35A 3u9fL-3emvA:
undetectable		 3u9fL-3emvA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f0n MEVALONATE
PYROPHOSPHATE
DECARBOXYLASE

(Mus musculus) 		PF00288
(GHMP_kinases_N) 		3 PHE A 263
CYH A 267
HIS A 264
 None
 0.86A 3u9fL-3f0nA:
undetectable		 3u9fL-3f0nA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fjy PROBABLE MUTT1
PROTEIN

(Bifidobacterium
adolescentis) 		PF00293
(NUDIX)
PF00300
(His_Phos_1) 		3 PHE A 139
CYH A 231
HIS A  72
 None
 1.14A 3u9fL-3fjyA:
undetectable		 3u9fL-3fjyA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gmj PROTEIN MOTHERS
AGAINST DPP

(Drosophila
melanogaster) 		no annotation 3 PHE D 356
CYH D 350
HIS D 354
 None
 1.15A 3u9fL-3gmjD:
undetectable		 3u9fL-3gmjD:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3grf ORNITHINE
CARBAMOYLTRANSFERASE

(Giardia
intestinalis) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		3 PHE A 224
CYH A 191
HIS A 189
 None
 1.03A 3u9fL-3grfA:
undetectable		 3u9fL-3grfA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2

(Burkholderia
cepacia) 		PF03241
(HpaB)
PF11794
(HpaB_N) 		3 PHE A3109
CYH A3149
HIS A3201
 None
 1.02A 3u9fL-3hwcA:
undetectable		 3u9fL-3hwcA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kkj AMINE OXIDASE,
FLAVIN-CONTAINING

(Pseudomonas
syringae group
genomosp. 3) 		PF01593
(Amino_oxidase)
PF13450
(NAD_binding_8) 		3 PHE A  31
CYH A 126
HIS A 148
 None
 1.29A 3u9fL-3kkjA:
undetectable		 3u9fL-3kkjA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ksy SON OF SEVENLESS
HOMOLOG 1

(Homo sapiens) 		PF00125
(Histone)
PF00169
(PH)
PF00617
(RasGEF)
PF00618
(RasGEF_N)
PF00621
(RhoGEF) 		3 PHE A 462
CYH A 471
HIS A 460
 None
 0.86A 3u9fL-3ksyA:
undetectable		 3u9fL-3ksyA:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ld1 REPLICASE
POLYPROTEIN 1A

(Avian
coronavirus) 		no annotation 3 PHE A 286
CYH A 331
HIS A 329
 None
 0.97A 3u9fL-3ld1A:
undetectable		 3u9fL-3ld1A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nwo PROLINE
IMINOPEPTIDASE

(Mycolicibacterium
smegmatis) 		PF00561
(Abhydrolase_1) 		3 PHE A  95
CYH A  99
HIS A  96
 None
 1.20A 3u9fL-3nwoA:
undetectable		 3u9fL-3nwoA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ont SPOT 14 PROTEIN

(Mus musculus) 		PF07084
(Spot_14) 		3 PHE A 121
CYH A 122
HIS A 118
 None
 1.13A 3u9fL-3ontA:
undetectable		 3u9fL-3ontA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pxl LACCASE

(Trametes
hirsuta) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 PHE A 337
CYH A 453
HIS A 458
 None
CU  A1503 (-2.1A)
CU  A1503 (-3.1A)
 0.92A 3u9fL-3pxlA:
undetectable		 3u9fL-3pxlA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pxl LACCASE

(Trametes
hirsuta) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 PHE A 463
CYH A 453
HIS A 395
 CU  A1503 ( 4.9A)
CU  A1503 (-2.1A)
CU  A1503 (-3.1A)
 1.32A 3u9fL-3pxlA:
undetectable		 3u9fL-3pxlA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rl3 METALLOPHOSPHOESTERA
SE MPPED2

(Rattus
norvegicus) 		PF00149
(Metallophos) 		3 PHE A 277
CYH A 273
HIS A  67
 5GP  A 951 (-4.8A)
None
MN  A 444 ( 3.4A)
 1.25A 3u9fL-3rl3A:
undetectable		 3u9fL-3rl3A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sp1 CYSTEINYL-TRNA
SYNTHETASE

(Borreliella
burgdorferi) 		PF01406
(tRNA-synt_1e) 		3 PHE A 266
CYH A 263
HIS A 236
 None
 1.27A 3u9fL-3sp1A:
undetectable		 3u9fL-3sp1A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6w LACCASE

(Steccherinum
ochraceum) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 PHE A 341
CYH A 453
HIS A 458
 None
CU  A 501 (-2.0A)
CU  A 501 (-3.3A)
 0.84A 3u9fL-3t6wA:
undetectable		 3u9fL-3t6wA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6w LACCASE

(Steccherinum
ochraceum) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 PHE A 463
CYH A 453
HIS A 397
 CU  A 501 (-4.9A)
CU  A 501 (-2.0A)
CU  A 501 (-3.1A)
 1.34A 3u9fL-3t6wA:
undetectable		 3u9fL-3t6wA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3td9 BRANCHED CHAIN AMINO
ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING PROTEIN

(Thermotoga
maritima) 		PF13458
(Peripla_BP_6) 		3 PHE A 134
CYH A 133
HIS A 264
 None
None
PHE  A 400 ( 4.5A)
 1.22A 3u9fL-3td9A:
undetectable		 3u9fL-3td9A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE

(Coxiella
burnetii) 		PF00551
(Formyl_trans_N) 		3 PHE A 214
CYH A 154
HIS A 212
 None
 1.06A 3u9fL-3tqrA:
undetectable		 3u9fL-3tqrA:
25.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x1b LACCASE

(Lentinus) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 PHE A 485
CYH A 475
HIS A 417
 CU  A 617 ( 4.9A)
CU  A 617 (-2.2A)
CU  A 617 (-3.1A)
 1.29A 3u9fL-3x1bA:
undetectable		 3u9fL-3x1bA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4arc LEUCINE--TRNA LIGASE

(Escherichia
coli) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1)
PF13603
(tRNA-synt_1_2) 		3 PHE A 253
CYH A 256
HIS A 311
 None
 1.29A 3u9fL-4arcA:
undetectable		 3u9fL-4arcA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ggj MITOCHONDRIAL
CARDIOLIPIN
HYDROLASE

(Mus musculus) 		PF13091
(PLDc_2) 		3 PHE A 156
CYH A  94
HIS A 154
 None
 0.95A 3u9fL-4ggjA:
undetectable		 3u9fL-4ggjA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hp4 EAG-LIKE K[+]
CHANNEL

(Drosophila
melanogaster) 		PF13426
(PAS_9) 		3 PHE A 110
CYH A 108
HIS A 129
 None
MLY  A 130 ( 3.9A)
None
 1.04A 3u9fL-4hp4A:
undetectable		 3u9fL-4hp4A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jhv LACCASE

(Coriolopsis
caperata) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 PHE A 460
CYH A 450
HIS A 394
 None
CU  A 503 (-2.2A)
CU  A 503 (-3.1A)
 1.29A 3u9fL-4jhvA:
undetectable		 3u9fL-4jhvA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k00 1,4-DIHYDROXY-2-NAPH
THOYL-COA HYDROLASE

(Synechocystis
sp. PCC 6803) 		PF03061
(4HBT) 		3 PHE A  89
CYH A  91
HIS A 111
 None
 0.99A 3u9fL-4k00A:
undetectable		 3u9fL-4k00A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k0r CRYPTOCHROME-1

(Mus musculus) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		3 PHE A   9
CYH A  33
HIS A   7
 None
 1.03A 3u9fL-4k0rA:
undetectable		 3u9fL-4k0rA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lmg IRON-REGULATED
TRANSCRIPTIONAL
ACTIVATOR AFT2

(Saccharomyces
cerevisiae) 		PF08731
(AFT) 		3 PHE A 111
CYH A  86
HIS A 133
 None
ZN  A 201 (-2.2A)
ZN  A 201 (-3.1A)
 1.21A 3u9fL-4lmgA:
undetectable		 3u9fL-4lmgA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nlb RIBOSOMAL RNA
PROCESSING PROTEIN 6

(Trypanosoma
brucei) 		PF00570
(HRDC)
PF01612
(DNA_pol_A_exo1) 		3 PHE A 283
CYH A 285
HIS A 275
 None
 1.01A 3u9fL-4nlbA:
undetectable		 3u9fL-4nlbA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nsx U3 SMALL NUCLEOLAR
RNA-ASSOCIATED
PROTEIN 21

(Saccharomyces
cerevisiae) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40) 		3 PHE A 124
CYH A 122
HIS A 172
 None
 1.29A 3u9fL-4nsxA:
undetectable		 3u9fL-4nsxA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ovy HALOACID
DEHALOGENASE DOMAIN
PROTEIN HYDROLASE

(Planctopirus
limnophila) 		PF12710
(HAD) 		3 PHE A 154
CYH A 161
HIS A 151
 None
 1.20A 3u9fL-4ovyA:
undetectable		 3u9fL-4ovyA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qvu UNCHARACTERIZED
PROTEIN

(Bacillus cereus) 		PF16285
(DUF4931) 		3 PHE A 222
CYH A 200
HIS A 197
 None
 1.04A 3u9fL-4qvuA:
undetectable		 3u9fL-4qvuA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rkm MCCA

(Wolinella
succinogenes) 		no annotation 3 PHE A 592
CYH A 562
HIS A 579
 HEM  A 813 ( 4.9A)
HEM  A 813 (-2.0A)
HEM  A 813 (-3.2A)
 1.08A 3u9fL-4rkmA:
undetectable		 3u9fL-4rkmA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u8h CRYPTOCHROME-2

(Mus musculus) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		3 PHE A  27
CYH A  51
HIS A  25
 None
 0.92A 3u9fL-4u8hA:
undetectable		 3u9fL-4u8hA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xny LIGHT CHAIN OF
ANTIBODY VRC08C

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 PHE L  91
CYH L  90
HIS L  32
 None
 1.05A 3u9fL-4xnyL:
undetectable		 3u9fL-4xnyL:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xzb CELA

(Geobacillus sp.
70PC53) 		PF00150
(Cellulase) 		3 PHE A  40
CYH A 268
HIS A  35
 None
 0.82A 3u9fL-4xzbA:
undetectable		 3u9fL-4xzbA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xzc NUCLEOPROTEIN

(Nairobi sheep
disease
orthonairovirus) 		PF02477
(Nairo_nucleo) 		3 PHE A 467
CYH A 465
HIS A 466
 None
 1.01A 3u9fL-4xzcA:
undetectable		 3u9fL-4xzcA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ehf LACCASE

(Antrodiella
faginea) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 PHE A 339
CYH A 451
HIS A 456
 None
CU  A 510 (-2.0A)
CU  A 510 (-3.1A)
 0.91A 3u9fL-5ehfA:
undetectable		 3u9fL-5ehfA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5igq E3 UBIQUITIN-PROTEIN
LIGASE RFWD2

(Homo sapiens) 		PF00400
(WD40) 		3 PHE A 573
CYH A 575
HIS A 581
 None
 1.14A 3u9fL-5igqA:
undetectable		 3u9fL-5igqA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5inf CARBOXYL TRANSFERASE

(Streptomyces
ambofaciens) 		PF01039
(Carboxyl_trans) 		3 PHE A 128
CYH A 101
HIS A  92
 None
 1.28A 3u9fL-5infA:
undetectable		 3u9fL-5infA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jdd TITIN

(Homo sapiens) 		PF07679
(I-set) 		3 PHE A 162
CYH A 112
HIS A 145
 None
 0.99A 3u9fL-5jddA:
undetectable		 3u9fL-5jddA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lb8 ATP-DEPENDENT DNA
HELICASE Q5

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF16124
(RecQ_Zn_bind) 		3 PHE A 221
CYH A 427
HIS A 413
 None
ZN  A 601 ( 4.2A)
None
 1.14A 3u9fL-5lb8A:
undetectable		 3u9fL-5lb8A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mew LACCASE 2

(Steccherinum
murashkinskyi) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 PHE A 341
CYH A 453
HIS A 458
 None
CU  A 504 (-2.1A)
CU  A 504 (-3.1A)
 0.84A 3u9fL-5mewA:
undetectable		 3u9fL-5mewA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mew LACCASE 2

(Steccherinum
murashkinskyi) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 PHE A 463
CYH A 453
HIS A 397
 None
CU  A 504 (-2.1A)
CU  A 504 (-3.1A)
 1.30A 3u9fL-5mewA:
undetectable		 3u9fL-5mewA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mz6 SEPARASE

(Caenorhabditis
elegans) 		PF03568
(Peptidase_C50) 		3 PHE 1 249
CYH 1 695
HIS 1 648
 None
 1.18A 3u9fL-5mz61:
undetectable		 3u9fL-5mz61:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o6c E3 UBIQUITIN-PROTEIN
LIGASE MYCBP2

(Homo sapiens) 		no annotation 3 PHE A4570
CYH A4572
HIS A4583
 None
 1.11A 3u9fL-5o6cA:
undetectable		 3u9fL-5o6cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ol2 ELECTRON TRANSFER
FLAVOPROTEIN SMALL
SUBUNIT

(Clostridioides
difficile) 		no annotation 3 PHE B 164
CYH B 167
HIS B 169
 None
 1.08A 3u9fL-5ol2B:
undetectable		 3u9fL-5ol2B:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t5x CRYPTOCHROME-1

(Mus musculus) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		3 PHE A   9
CYH A  33
HIS A   7
 None
 1.03A 3u9fL-5t5xA:
undetectable		 3u9fL-5t5xA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tnx ALCOHOL
DEHYDROGENASE
ZINC-BINDING DOMAIN
PROTEIN

(Burkholderia
ambifaria) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		3 PHE A 143
CYH A 176
HIS A  68
 None
 0.89A 3u9fL-5tnxA:
undetectable		 3u9fL-5tnxA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tzm OBSCURIN

(Homo sapiens) 		no annotation 3 PHE A  78
CYH A  25
HIS A  61
 None
 1.12A 3u9fL-5tzmA:
undetectable		 3u9fL-5tzmA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vab ATXR5 PHD DOMAIN

(Glycine max) 		PF00628
(PHD) 		3 PHE A  50
CYH A  51
HIS A  48
 None
ZN  A 101 (-2.2A)
ZN  A 101 (-3.2A)
 0.64A 3u9fL-5vabA:
undetectable		 3u9fL-5vabA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w1a MYOSIN HEAVY CHAIN,
MUSCLE

(Drosophila
melanogaster) 		no annotation 3 PHE A 156
CYH A 139
HIS A 154
 None
 1.21A 3u9fL-5w1aA:
undetectable		 3u9fL-5w1aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d6v TELOMERASE
HOLOENZYME TEB
HETEROTRIMER TEB3
SUBUNIT

(Tetrahymena
thermophila) 		no annotation 3 PHE F  45
CYH F  33
HIS F  53
 None
 1.14A 3u9fL-6d6vF:
undetectable		 3u9fL-6d6vF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ejj WLAC PROTEIN

(Campylobacter
jejuni) 		no annotation 3 PHE A 170
CYH A 168
HIS A 169
 None
 1.16A 3u9fL-6ejjA:
undetectable		 3u9fL-6ejjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f85 CYTOCHROME P450
CYP260A1

(Sorangium
cellulosum) 		no annotation 3 PHE A 374
CYH A 273
HIS A 243
 None
 1.33A 3u9fL-6f85A:
undetectable		 3u9fL-6f85A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fiv RETROPEPSIN

(Feline
immunodeficiency
virus) 		PF00077
(RVP) 		3 PHE A  86
CYH A  84
HIS A  72
 None
 1.08A 3u9fL-6fivA:
undetectable		 3u9fL-6fivA:
17.51