SIMILAR PATTERNS OF AMINO ACIDS FOR 3U5K_D_08JD4

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1e6i TRANSCRIPTIONAL
ACTIVATOR GCN5


(Saccharomyces
cerevisiae)
PF00439
(Bromodomain)
4 TRP A 350
PRO A 351
VAL A 356
ASN A 407
None
0.57A 3u5kD-1e6iA:
16.2
3u5kD-1e6iA:
34.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kcz BETA-METHYLASPARTASE

(Clostridium
tetanomorphum)
PF05034
(MAAL_N)
PF07476
(MAAL_C)
4 VAL A 239
LEU A 211
LEU A 204
ILE A 258
None
0.92A 3u5kD-1kczA:
undetectable
3u5kD-1kczA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kzh PHOSPHOFRUCTOKINASE

(Borreliella
burgdorferi)
PF00365
(PFK)
4 PRO A 202
LEU A 482
ASN A 211
ILE A 214
None
0.87A 3u5kD-1kzhA:
undetectable
3u5kD-1kzhA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ldj CULLIN HOMOLOG 1

(Homo sapiens)
PF00888
(Cullin)
PF10557
(Cullin_Nedd8)
4 VAL A  49
LEU A  88
ASN A 141
ILE A 159
None
0.91A 3u5kD-1ldjA:
undetectable
3u5kD-1ldjA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tdf THIOREDOXIN
REDUCTASE


(Escherichia
coli)
PF07992
(Pyr_redox_2)
5 PRO A  53
VAL A  49
LEU A  64
LEU A  43
ILE A 296
None
FAD  A 500 (-3.4A)
None
FAD  A 500 (-3.3A)
None
1.09A 3u5kD-1tdfA:
undetectable
3u5kD-1tdfA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ue8 367AA LONG
HYPOTHETICAL
CYTOCHROME P450


(Sulfurisphaera
tokodaii)
PF00067
(p450)
4 PRO A 123
LEU A 104
LEU A 105
ILE A 219
None
0.75A 3u5kD-1ue8A:
undetectable
3u5kD-1ue8A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vhe AMINOPEPTIDASE/GLUCA
NASE HOMOLOG


(Bacillus
subtilis)
PF05343
(Peptidase_M42)
4 VAL A 206
LEU A 194
LEU A 197
ILE A 343
None
0.84A 3u5kD-1vheA:
undetectable
3u5kD-1vheA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xe7 HYPOTHETICAL 22.5
KDA PROTEIN IN
TUB1-CPR3 INTERGENIC
REGION


(Saccharomyces
cerevisiae)
PF06172
(Cupin_5)
4 PRO A  63
VAL A  74
ASN A 100
ILE A  99
None
None
EDO  A 306 (-3.7A)
None
0.93A 3u5kD-1xe7A:
undetectable
3u5kD-1xe7A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xr4 PUTATIVE CITRATE
LYASE ALPHA
CHAIN/CITRATE-ACP
TRANSFERASE


(Salmonella
enterica)
PF04223
(CitF)
4 VAL A 433
LEU A 449
LEU A 453
ILE A 258
None
0.83A 3u5kD-1xr4A:
undetectable
3u5kD-1xr4A:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yfy 3-HYDROXYANTHRANILAT
E-3,4-DIOXYGENASE


(Cupriavidus
metallidurans)
PF06052
(3-HAO)
4 TRP A  31
VAL A  40
LEU A 107
LEU A  62
None
0.90A 3u5kD-1yfyA:
undetectable
3u5kD-1yfyA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bac PUTATIVE
AMINOOXIDASE


(Cutibacterium
acnes)
PF01593
(Amino_oxidase)
4 VAL A 181
LEU A 185
ILE A 162
MET A 302
None
0.92A 3u5kD-2bacA:
undetectable
3u5kD-2bacA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bdw HYPOTHETICAL PROTEIN
K11E8.1D


(Caenorhabditis
elegans)
PF00069
(Pkinase)
4 VAL A 152
LEU A  97
LEU A 141
ILE A 116
None
0.93A 3u5kD-2bdwA:
undetectable
3u5kD-2bdwA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
C-PHYCOCYANIN BETA
SUBUNIT


(Gracilaria
chilensis)
PF00502
(Phycobilisome)
4 VAL B  41
LEU A  24
LEU B  38
ILE A   5
None
PEB  B1175 ( 4.6A)
PEB  B1175 ( 4.0A)
None
0.90A 3u5kD-2bv8B:
undetectable
3u5kD-2bv8B:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dcq PUTATIVE PROTEIN
AT4G01050


(Arabidopsis
thaliana)
no annotation 4 VAL A  94
LEU A  62
LEU A  65
ILE A  27
None
0.76A 3u5kD-2dcqA:
undetectable
3u5kD-2dcqA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dld D-LACTATE
DEHYDROGENASE


(Lactobacillus
helveticus)
PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C)
4 VAL A  52
LEU A  36
ASN A  83
ILE A  84
None
0.90A 3u5kD-2dldA:
undetectable
3u5kD-2dldA:
16.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2


(Homo sapiens)
PF00439
(Bromodomain)
8 TRP A  31
PRO A  32
VAL A  37
LEU A  42
LEU A  44
ASN A  90
ILE A  96
MET A  99
None
0.59A 3u5kD-2dvrA:
20.8
3u5kD-2dvrA:
70.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f4z TGTWINSCAN_2721 - E2
DOMAIN


(Toxoplasma
gondii)
PF00179
(UQ_con)
4 PRO A 109
LEU A  37
ILE A  98
MET A 111
None
0.93A 3u5kD-2f4zA:
undetectable
3u5kD-2f4zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gsk VITAMIN B12
TRANSPORTER BTUB


(Escherichia
coli)
PF00593
(TonB_dep_Rec)
PF07715
(Plug)
4 PRO A 412
LEU A 401
LEU A 398
ASN A 362
None
0.92A 3u5kD-2gskA:
undetectable
3u5kD-2gskA:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2it1 362AA LONG
HYPOTHETICAL
MALTOSE/MALTODEXTRIN
TRANSPORT
ATP-BINDING PROTEIN


(Pyrococcus
horikoshii)
PF00005
(ABC_tran)
4 VAL A 172
LEU A 161
LEU A 164
ILE A 144
None
0.93A 3u5kD-2it1A:
undetectable
3u5kD-2it1A:
15.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3


(Mus musculus)
PF00439
(Bromodomain)
7 TRP A  57
PRO A  58
LEU A  68
LEU A  70
ASN A 116
ILE A 122
MET A 125
None
0.93A 3u5kD-2l5eA:
16.8
3u5kD-2l5eA:
77.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okc TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN


(Bacteroides
thetaiotaomicron)
PF02384
(N6_Mtase)
PF12161
(HsdM_N)
4 PRO A 177
LEU A 185
ILE A 256
MET A 292
None
0.84A 3u5kD-2okcA:
undetectable
3u5kD-2okcA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pqd 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE


(Agrobacterium
sp.)
PF00275
(EPSP_synthase)
4 PRO A 329
VAL A 333
LEU A 365
ILE A 406
None
0.81A 3u5kD-2pqdA:
undetectable
3u5kD-2pqdA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qip PROTEIN OF UNKNOWN
FUNCTION VPA0982


(Vibrio
parahaemolyticus)
PF01936
(NYN)
4 PRO A 104
VAL A 109
LEU A  12
ILE A 100
None
0.88A 3u5kD-2qipA:
undetectable
3u5kD-2qipA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v1n PROTEIN KIN HOMOLOG

(Homo sapiens)
PF10357
(Kin17_mid)
4 TRP A  72
LEU A  28
LEU A  31
ASN A  42
None
0.93A 3u5kD-2v1nA:
undetectable
3u5kD-2v1nA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vgq SUGAR ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN,MITOCHONDRIA
L
ANTIVIRAL-SIGNALING
PROTEIN


(Escherichia
coli;
Homo sapiens)
PF13416
(SBP_bac_8)
PF16739
(CARD_2)
4 VAL A 391
LEU A 453
LEU A 445
ILE A 381
None
0.72A 3u5kD-2vgqA:
undetectable
3u5kD-2vgqA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vml PHYCOCYANIN ALPHA
CHAIN
PHYCOCYANIN BETA
CHAIN


(Gloeobacter
violaceus)
PF00502
(Phycobilisome)
4 VAL B  41
LEU A  24
LEU B  38
ILE A   5
None
CYC  B1153 (-4.1A)
CYC  B1153 (-3.8A)
None
0.86A 3u5kD-2vmlB:
undetectable
3u5kD-2vmlB:
17.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2wp1 BROMODOMAIN
TESTIS-SPECIFIC
PROTEIN


(Mus musculus)
PF00439
(Bromodomain)
6 TRP A 292
PRO A 293
VAL A 298
LEU A 305
ASN A 351
MET A 360
None
0.62A 3u5kD-2wp1A:
16.8
3u5kD-2wp1A:
38.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2wp1 BROMODOMAIN
TESTIS-SPECIFIC
PROTEIN


(Mus musculus)
PF00439
(Bromodomain)
6 TRP A 292
VAL A 298
LEU A 303
LEU A 305
ASN A 351
MET A 360
None
0.77A 3u5kD-2wp1A:
16.8
3u5kD-2wp1A:
38.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2yek BROMODOMAIN-CONTAINI
NG PROTEIN 2


(Homo sapiens)
PF00439
(Bromodomain)
8 TRP A  97
PRO A  98
VAL A 103
LEU A 108
LEU A 110
ASN A 156
ILE A 162
MET A 165
None
EAM  A1188 (-4.6A)
EAM  A1188 (-4.4A)
EAM  A1188 ( 3.8A)
EAM  A1188 (-4.5A)
EAM  A1188 (-3.2A)
EAM  A1188 (-3.8A)
EAM  A1188 ( 4.1A)
0.56A 3u5kD-2yekA:
20.5
3u5kD-2yekA:
70.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bwt PROTEIN PUF4

(Saccharomyces
cerevisiae)
PF00806
(PUF)
4 PRO A 865
LEU A 832
LEU A 841
ILE A 862
None
0.92A 3u5kD-3bwtA:
undetectable
3u5kD-3bwtA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dcx PROTEIN OF UNKNOWN
FUNCTION (DUF1696)
WITH
PLECKSTRIN-HOMOLOGY
DOMAINS


(Shewanella
loihica)
PF08000
(bPH_1)
4 VAL A  45
LEU A  19
LEU A  33
ILE A  26
None
0.89A 3u5kD-3dcxA:
undetectable
3u5kD-3dcxA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dls PAS
DOMAIN-CONTAINING
SERINE/THREONINE-PRO
TEIN KINASE


(Homo sapiens)
PF00069
(Pkinase)
4 VAL A1265
LEU A1104
LEU A1100
ILE A1136
None
0.89A 3u5kD-3dlsA:
undetectable
3u5kD-3dlsA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gt0 PYRROLINE-5-CARBOXYL
ATE REDUCTASE


(Bacillus cereus)
PF03807
(F420_oxidored)
PF14748
(P5CR_dimer)
4 VAL A 147
LEU A 133
ILE A  96
MET A  13
None
0.80A 3u5kD-3gt0A:
undetectable
3u5kD-3gt0A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hmh TRANSCRIPTION
INITIATION FACTOR
TFIID 210 KDA
SUBUNIT


(Homo sapiens)
PF00439
(Bromodomain)
4 TRP A1545
PRO A1546
VAL A1551
ASN A1602
None
0.78A 3u5kD-3hmhA:
12.7
3u5kD-3hmhA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i04 CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT ALPHA


(Moorella
thermoacetica)
PF03598
(CdhC)
4 VAL M  53
LEU M 119
LEU M 116
ILE M  44
None
0.93A 3u5kD-3i04M:
undetectable
3u5kD-3i04M:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ivr PUTATIVE
LONG-CHAIN-FATTY-ACI
D COA LIGASE


(Rhodopseudomonas
palustris)
PF00501
(AMP-binding)
4 VAL A 118
LEU A 100
ILE A  62
MET A  70
None
0.85A 3u5kD-3ivrA:
undetectable
3u5kD-3ivrA:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k2k PUTATIVE
CARBOXYPEPTIDASE


(Burkholderia
mallei)
PF00246
(Peptidase_M14)
4 VAL A 212
LEU A 148
LEU A 137
ILE A 256
None
0.93A 3u5kD-3k2kA:
undetectable
3u5kD-3k2kA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l8d METHYLTRANSFERASE

(Bacillus
thuringiensis)
PF08241
(Methyltransf_11)
4 VAL A 200
ASN A 124
ILE A 123
MET A 121
None
0.80A 3u5kD-3l8dA:
undetectable
3u5kD-3l8dA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mal STROMAL CELL-DERIVED
FACTOR 2-LIKE
PROTEIN


(Arabidopsis
thaliana)
PF02815
(MIR)
4 VAL A 163
LEU A 148
LEU A 165
ILE A  43
None
0.81A 3u5kD-3malA:
undetectable
3u5kD-3malA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3niv GLUTATHIONE
S-TRANSFERASE


(Legionella
pneumophila)
PF13417
(GST_N_3)
4 VAL A  15
LEU A   3
LEU A  57
ILE A  24
None
0.90A 3u5kD-3nivA:
undetectable
3u5kD-3nivA:
19.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3nxb CAT EYE SYNDROME
CRITICAL REGION
PROTEIN 2


(Homo sapiens)
PF00439
(Bromodomain)
5 TRP A 457
PRO A 458
VAL A 463
ASN A 514
MET A 523
None
None
EDO  A   1 (-4.3A)
EDO  A   1 (-3.3A)
None
0.50A 3u5kD-3nxbA:
16.6
3u5kD-3nxbA:
32.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988


(Thermus
thermophilus)
PF02626
(CT_A_B)
PF02682
(CT_C_D)
4 VAL A 445
LEU A 408
LEU A 394
ILE A 489
None
0.86A 3u5kD-3oepA:
undetectable
3u5kD-3oepA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3owt DNA-BINDING PROTEIN
RAP1


(Saccharomyces
cerevisiae)
PF11626
(Rap1_C)
4 PRO A 766
LEU A 758
LEU A 755
ILE A 724
None
0.89A 3u5kD-3owtA:
undetectable
3u5kD-3owtA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p9z UROPORPHYRINOGEN III
COSYNTHASE (HEMD)


(Helicobacter
pylori)
PF02602
(HEM4)
4 VAL A 110
LEU A 126
ILE A 101
MET A  88
None
0.72A 3u5kD-3p9zA:
undetectable
3u5kD-3p9zA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pkj NAD-DEPENDENT
DEACETYLASE
SIRTUIN-6


(Homo sapiens)
PF02146
(SIR2)
4 PRO A 290
VAL A 102
LEU A 104
LEU A  99
None
0.93A 3u5kD-3pkjA:
undetectable
3u5kD-3pkjA:
17.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3q2e BROMODOMAIN AND WD
REPEAT-CONTAINING
PROTEIN 1


(Homo sapiens)
PF00439
(Bromodomain)
4 PRO A1337
VAL A1342
ILE A1400
MET A1403
None
0.41A 3u5kD-3q2eA:
16.5
3u5kD-3q2eA:
33.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q98 TRANSCARBAMYLASE

(Escherichia
coli)
PF00185
(OTCace)
PF02729
(OTCace_N)
4 PRO A 154
LEU A  87
LEU A  82
ILE A 119
None
0.77A 3u5kD-3q98A:
undetectable
3u5kD-3q98A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r5x D-ALANINE--D-ALANINE
LIGASE


(Bacillus
anthracis)
PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C)
4 VAL A  70
LEU A  58
LEU A  60
ILE A  38
None
0.80A 3u5kD-3r5xA:
undetectable
3u5kD-3r5xA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wpe TOLL-LIKE RECEPTOR 9

(Bos taurus)
PF13516
(LRR_6)
PF13855
(LRR_8)
4 VAL A 419
LEU A 397
LEU A 421
ILE A 409
None
0.88A 3u5kD-3wpeA:
undetectable
3u5kD-3wpeA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ad8 DNA REPAIR PROTEIN
RECN


(Deinococcus
radiodurans)
PF02463
(SMC_N)
4 VAL A 530
LEU A  50
LEU A  48
ILE A  70
None
0.93A 3u5kD-4ad8A:
undetectable
3u5kD-4ad8A:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aef NEOPULLULANASE
(ALPHA-AMYLASE II)


(Pyrococcus
furiosus)
PF00128
(Alpha-amylase)
PF02903
(Alpha-amylase_N)
PF16561
(AMPK1_CBM)
4 TRP A 400
VAL A 302
LEU A 292
ILE A 261
None
0.82A 3u5kD-4aefA:
undetectable
3u5kD-4aefA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aij TRANSCRIPTIONAL
REGULATOR SLYA


(Yersinia
pseudotuberculosis)
PF01047
(MarR)
4 PRO A  98
VAL A 103
LEU A  27
LEU A  29
None
0.89A 3u5kD-4aijA:
undetectable
3u5kD-4aijA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b6z FAMILY M14
UNASSIGNED PEPTIDASE


(Burkholderia
cenocepacia)
PF00246
(Peptidase_M14)
4 VAL A 212
LEU A 148
LEU A 137
ILE A 256
None
0.92A 3u5kD-4b6zA:
undetectable
3u5kD-4b6zA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ei8 PLASMID REPLICATION
PROTEIN REPX


(Bacillus cereus)
PF00091
(Tubulin)
4 VAL A 366
LEU A 150
LEU A 121
ILE A 180
None
0.89A 3u5kD-4ei8A:
undetectable
3u5kD-4ei8A:
16.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hbx BROMODOMAIN-CONTAINI
NG PROTEIN 4


(Homo sapiens)
PF00439
(Bromodomain)
8 TRP A  81
PRO A  82
VAL A  87
LEU A  92
LEU A  94
ASN A 140
ILE A 146
MET A 149
None
14X  A 201 (-4.4A)
14X  A 201 (-4.7A)
14X  A 201 (-4.4A)
None
14X  A 201 (-3.1A)
14X  A 201 ( 4.0A)
14X  A 201 (-3.5A)
0.58A 3u5kD-4hbxA:
24.2
3u5kD-4hbxA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hwi BAG FAMILY MOLECULAR
CHAPERONE REGULATOR
1


(Arabidopsis
thaliana)
PF02179
(BAG)
PF14560
(Ubiquitin_2)
4 PRO B  98
LEU B 134
LEU B 108
ILE B  80
None
0.65A 3u5kD-4hwiB:
2.3
3u5kD-4hwiB:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hzu ENERGY-COUPLING
FACTOR TRANSPORTER
ATP-BINDING PROTEIN
ECFA 1


(Lactobacillus
brevis)
PF00005
(ABC_tran)
4 PRO B  59
LEU B  80
LEU B  83
ILE B  64
None
0.91A 3u5kD-4hzuB:
undetectable
3u5kD-4hzuB:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i1t RNA-DIRECTED RNA
POLYMERASE L


(Cali
mammarenavirus)
PF17296
(ArenaCapSnatch)
4 PRO A  87
LEU A 125
LEU A 129
ILE A  71
None
0.91A 3u5kD-4i1tA:
2.9
3u5kD-4i1tA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i62 AMINO ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING
PROTEIN, PUTATIVE


(Streptococcus
pneumoniae)
PF00497
(SBP_bac_3)
4 PRO A  86
VAL A  42
LEU A  82
ILE A  63
None
0.87A 3u5kD-4i62A:
undetectable
3u5kD-4i62A:
17.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ldf GCN5 LIKE ACETYLASE
+ BROMODOMAIN


(Cryptosporidium
parvum)
PF00439
(Bromodomain)
4 TRP A  31
PRO A  32
VAL A  37
ASN A  88
None
None
GOL  A 201 ( 4.9A)
GOL  A 201 (-2.7A)
0.57A 3u5kD-4ldfA:
15.2
3u5kD-4ldfA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u09 LIC12759

(Leptospira
interrogans)
PF13855
(LRR_8)
4 VAL A 313
LEU A 299
LEU A 322
ILE A 306
None
0.92A 3u5kD-4u09A:
undetectable
3u5kD-4u09A:
14.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4uyd BROMODOMAIN-CONTAINI
NG PROTEIN 4


(Homo sapiens)
PF00439
(Bromodomain)
8 TRP A  81
PRO A  82
VAL A  87
LEU A  92
LEU A  94
ASN A 140
ILE A 146
MET A 149
None
V1T  A1171 (-4.2A)
V1T  A1171 (-4.9A)
V1T  A1171 (-3.8A)
None
V1T  A1171 (-3.1A)
DMS  A1169 ( 4.3A)
DMS  A1169 ( 3.8A)
0.36A 3u5kD-4uydA:
23.7
3u5kD-4uydA:
92.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4uyg BROMODOMAIN-CONTAINI
NG PROTEIN 2


(Homo sapiens)
PF00439
(Bromodomain)
7 TRP A 370
PRO A 371
VAL A 376
LEU A 381
LEU A 383
ASN A 429
MET A 438
None
None
73B  A1456 (-4.0A)
73B  A1456 (-4.9A)
73B  A1456 (-4.9A)
73B  A1456 (-3.3A)
73B  A1456 ( 3.8A)
0.65A 3u5kD-4uygA:
18.0
3u5kD-4uygA:
34.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wk0 INTEGRIN BETA-1

(Homo sapiens)
PF00362
(Integrin_beta)
PF17205
(PSI_integrin)
4 VAL B 436
LEU B 101
LEU B 438
ILE B 375
None
0.88A 3u5kD-4wk0B:
undetectable
3u5kD-4wk0B:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgm MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 3


(Homo sapiens)
PF16953
(PRORP)
4 PRO A 210
LEU A 216
ASN A 246
ILE A 236
None
0.89A 3u5kD-4xgmA:
undetectable
3u5kD-4xgmA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xpz RNA POLYMERASE II
SUBUNIT A C-TERMINAL
DOMAIN PHOSPHATASE


(Schizosaccharomyces
pombe)
PF03031
(NIF)
PF12738
(PTCB-BRCT)
4 PRO A 355
LEU A 376
LEU A 377
ILE A 321
PG4  A 603 (-4.5A)
None
None
None
0.93A 3u5kD-4xpzA:
undetectable
3u5kD-4xpzA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xz3 ACYL-COA SYNTHETASE
(NDP FORMING)


(Candidatus
Korarchaeum
cryptofilum)
PF13380
(CoA_binding_2)
PF13607
(Succ_CoA_lig)
4 PRO A 328
VAL A 374
LEU A 377
ILE A 350
None
0.82A 3u5kD-4xz3A:
undetectable
3u5kD-4xz3A:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yzz TRAP TRANSPORTER
SOLUTE BINDING
PROTEIN


(Bordetella
bronchiseptica)
PF03480
(DctP)
4 VAL A 311
LEU A 191
LEU A 188
ILE A 167
None
0.85A 3u5kD-4yzzA:
undetectable
3u5kD-4yzzA:
16.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4z93 BROMODOMAIN-CONTAINI
NG PROTEIN 4


(Homo sapiens)
PF00439
(Bromodomain)
7 TRP A 374
PRO A 375
VAL A 380
LEU A 385
LEU A 387
ASN A 433
MET A 442
4LD  A 501 (-3.9A)
4LD  A 501 (-3.9A)
4LD  A 501 ( 3.8A)
4LD  A 501 (-4.1A)
4LD  A 501 (-4.4A)
4LD  A 501 (-2.8A)
4LD  A 501 ( 3.4A)
0.59A 3u5kD-4z93A:
17.8
3u5kD-4z93A:
36.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zw0 3-HYDROXYACYL-[ACYL-
CARRIER-PROTEIN]
DEHYDRATASE FABZ


(Candidatus
Liberibacter
asiaticus)
PF07977
(FabA)
4 VAL A  28
LEU A  15
LEU A  19
ILE A  79
None
0.83A 3u5kD-4zw0A:
undetectable
3u5kD-4zw0A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a4p UBIQUITIN-CONJUGATIN
G ENZYME E2 Z


(Homo sapiens)
PF00179
(UQ_con)
4 VAL A 187
LEU A 189
LEU A 192
MET A 119
None
0.88A 3u5kD-5a4pA:
undetectable
3u5kD-5a4pA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f3y UNCONVENTIONAL
MYOSIN-VIIB


(Mus musculus)
PF00784
(MyTH4)
4 VAL A1433
LEU A1450
LEU A1436
ILE A1410
None
0.90A 3u5kD-5f3yA:
2.5
3u5kD-5f3yA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gqf LACTO-N-BIOSIDASE

(Bifidobacterium
longum)
no annotation 4 VAL A 214
LEU A 229
LEU A 232
ILE A 116
None
0.79A 3u5kD-5gqfA:
undetectable
3u5kD-5gqfA:
12.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5hjc BROMODOMAIN-CONTAINI
NG PROTEIN 3


(Homo sapiens)
PF00439
(Bromodomain)
7 TRP A 332
PRO A 333
VAL A 338
LEU A 343
LEU A 345
ASN A 391
MET A 400
None
0.75A 3u5kD-5hjcA:
18.0
3u5kD-5hjcA:
39.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5izh RNA-DIRECTED RNA
POLYMERASE L


(Lassa
mammarenavirus)
PF17296
(ArenaCapSnatch)
4 PRO A  88
LEU A 126
LEU A 130
ILE A  72
None
0.92A 3u5kD-5izhA:
4.5
3u5kD-5izhA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j68 ASTROTACTIN-2

(Homo sapiens)
PF01823
(MACPF)
4 PRO A 767
VAL A 815
LEU A 763
ILE A 753
None
0.93A 3u5kD-5j68A:
undetectable
3u5kD-5j68A:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k66 NTA1P

(Saccharomyces
cerevisiae)
PF00795
(CN_hydrolase)
4 PRO A 219
VAL A 387
LEU A 215
ILE A 105
None
0.89A 3u5kD-5k66A:
undetectable
3u5kD-5k66A:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lc5 NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
2, MITOCHONDRIAL


(Bos taurus)
PF00346
(Complex1_49kDa)
4 VAL D 184
LEU D 207
LEU D 203
ILE D 144
None
0.67A 3u5kD-5lc5D:
undetectable
3u5kD-5lc5D:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lew DNA POLYMERASE III
SUBUNIT ALPHA


(Mycobacterium
tuberculosis)
no annotation 4 VAL A 724
LEU A 700
LEU A 696
ILE A 775
None
0.92A 3u5kD-5lewA:
undetectable
3u5kD-5lewA:
8.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5lpk HISTONE
ACETYLTRANSFERASE
P300


(Homo sapiens)
PF00439
(Bromodomain)
4 PRO A1074
VAL A1079
LEU A1084
ASN A1132
XDM  A1201 (-3.9A)
XDM  A1201 (-4.7A)
XDM  A1201 ( 4.4A)
XDM  A1201 (-3.1A)
0.68A 3u5kD-5lpkA:
17.3
3u5kD-5lpkA:
31.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mg2 TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 1


(Homo sapiens)
PF00439
(Bromodomain)
4 TRP A1526
PRO A1527
VAL A1532
ASN A1583
None
7M8  A1704 (-3.8A)
7M8  A1704 (-3.5A)
7M8  A1704 (-3.1A)
0.48A 3u5kD-5mg2A:
13.1
3u5kD-5mg2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ml0 HISTONE
ACETYLTRANSFERASE
KAT2B


(Mus musculus)
no annotation 4 TRP A 745
PRO A 746
VAL A 751
ASN A 802
None
P2L  A 901 (-4.7A)
P2L  A 901 ( 4.2A)
P2L  A 901 (-3.2A)
0.67A 3u5kD-5ml0A:
15.9
3u5kD-5ml0A:
26.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5n15 BROMODOMAIN-CONTAINI
NG FACTOR 1


(Candida
albicans)
PF00439
(Bromodomain)
5 PRO A 233
VAL A 238
ASN A 291
ILE A 297
MET A 300
IOD  A 405 ( 4.4A)
None
IOD  A 404 (-3.9A)
IOD  A 404 ( 4.8A)
None
0.44A 3u5kD-5n15A:
18.2
3u5kD-5n15A:
35.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nmi CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL


(Bos taurus)
PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
4 VAL A 366
LEU A 392
LEU A   8
ILE A 399
None
0.80A 3u5kD-5nmiA:
undetectable
3u5kD-5nmiA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nn8 LYSOSOMAL
ALPHA-GLUCOSIDASE


(Homo sapiens)
no annotation 4 VAL A 939
LEU A 941
LEU A 901
ILE A 885
CSO  A 938 ( 2.8A)
None
None
None
0.81A 3u5kD-5nn8A:
undetectable
3u5kD-5nn8A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ot1 PULLULANASE TYPE II,
GH13 FAMILY


(Thermococcus
kodakarensis)
no annotation 4 TRP A 492
VAL A 415
LEU A 405
ILE A 374
None
0.87A 3u5kD-5ot1A:
undetectable
3u5kD-5ot1A:
17.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5tpx HISTONE
ACETYLTRANSFERASE
GCN5


(Plasmodium
falciparum)
PF00439
(Bromodomain)
4 TRP A1379
PRO A1380
VAL A1385
ASN A1436
None
None
7H7  A1505 (-4.0A)
7H7  A1505 (-3.1A)
0.70A 3u5kD-5tpxA:
15.9
3u5kD-5tpxA:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5u6v BROMODOMAIN-CONTAINI
NG PROTEIN 2


(Homo sapiens)
no annotation 7 TRP A 370
PRO A 371
VAL A 376
LEU A 381
LEU A 383
ASN A 429
MET A 438
None
7WY  A 501 (-4.4A)
7WY  A 501 ( 4.5A)
7WY  A 501 (-4.9A)
None
7WY  A 501 (-3.4A)
7WY  A 501 ( 3.9A)
0.48A 3u5kD-5u6vA:
18.0
3u5kD-5u6vA:
40.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u7g CREB-BINDING PROTEIN

(Mus musculus)
PF00439
(Bromodomain)
PF00569
(ZZ)
PF06001
(DUF902)
PF08214
(HAT_KAT11)
4 PRO A1111
VAL A1116
LEU A1121
ASN A1169
None
0.78A 3u5kD-5u7gA:
16.7
3u5kD-5u7gA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uib OXIDOREDUCTASE
PROTEIN


(Agrobacterium
tumefaciens)
PF01408
(GFO_IDH_MocA)
4 PRO A 242
LEU A 179
ASN A 126
ILE A 291
None
TLA  A 402 (-4.0A)
NAD  A 401 (-3.0A)
NAD  A 401 ( 4.7A)
0.82A 3u5kD-5uibA:
undetectable
3u5kD-5uibA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5usx THIOREDOXIN
REDUCTASE


(Vibrio
vulnificus)
PF07992
(Pyr_redox_2)
5 PRO A  54
VAL A  50
LEU A  65
LEU A  44
ILE A 296
None
FAD  A 402 (-3.4A)
None
FAD  A 402 (-4.1A)
None
1.10A 3u5kD-5usxA:
undetectable
3u5kD-5usxA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v84 CAT EYE SYNDROME
CRITICAL REGION
PROTEIN 2


(Homo sapiens)
PF00439
(Bromodomain)
5 TRP A 457
PRO A 458
VAL A 463
ASN A 514
MET A 523
None
96V  A 602 (-4.5A)
96V  A 602 (-3.9A)
96V  A 602 (-2.6A)
None
0.33A 3u5kD-5v84A:
16.7
3u5kD-5v84A:
28.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5vbr BROMODOMAIN
TESTIS-SPECIFIC
PROTEIN


(Homo sapiens)
no annotation 8 TRP A  50
PRO A  51
VAL A  56
LEU A  61
LEU A  63
ASN A 109
ILE A 115
MET A 118
CL  A 208 (-4.9A)
IBI  A 201 (-4.3A)
IBI  A 201 ( 4.6A)
IBI  A 201 (-4.2A)
IBI  A 201 (-4.9A)
IBI  A 201 (-3.3A)
IBI  A 201 ( 3.8A)
None
0.49A 3u5kD-5vbrA:
19.4
3u5kD-5vbrA:
68.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w4c THIOREDOXIN
REDUCTASE


(Cryptococcus
neoformans)
no annotation 4 PRO A  83
VAL A  79
LEU A  73
ILE A 326
None
FAD  A 401 ( 3.8A)
FAD  A 401 (-3.9A)
None
0.88A 3u5kD-5w4cA:
undetectable
3u5kD-5w4cA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xvh 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
NAD-BINDING PROTEIN


(Pyrobaculum
calidifontis)
no annotation 4 PRO A  38
VAL A  44
LEU A  20
LEU A  25
None
0.80A 3u5kD-5xvhA:
undetectable
3u5kD-5xvhA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zln TOLL-LIKE RECEPTOR 9

(Mus musculus)
no annotation 4 VAL A 420
LEU A 398
LEU A 422
ILE A 410
None
0.93A 3u5kD-5zlnA:
undetectable
3u5kD-5zlnA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zvs VP2

(Aquareovirus C)
no annotation 4 PRO 2 183
LEU 2 160
LEU 2 157
ILE 2  52
None
0.83A 3u5kD-5zvs2:
undetectable
3u5kD-5zvs2:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bvp 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE


(Cupriavidus
metallidurans)
no annotation 4 TRP A  31
VAL A  40
LEU A 107
LEU A  62
None
0.93A 3u5kD-6bvpA:
undetectable
3u5kD-6bvpA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6byo VOLTAGE-DEPENDENT
L-TYPE CALCIUM
CHANNEL SUBUNIT
ALPHA-1S


(Oryctolagus
cuniculus)
no annotation 4 PRO A 172
VAL A 176
LEU A 565
ILE A 572
None
0.93A 3u5kD-6byoA:
undetectable
3u5kD-6byoA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dne BROMODOMAIN-CONTAINI
NG PROTEIN 4


(Homo sapiens)
no annotation 8 TRP A  81
PRO A  82
VAL A  87
LEU A  92
LEU A  94
ASN A 140
ILE A 146
MET A 149
None
H1V  A 501 (-4.6A)
H1V  A 501 ( 4.4A)
H1V  A 501 (-4.2A)
H1V  A 501 (-4.7A)
H1V  A 501 (-3.2A)
H1V  A 501 (-3.8A)
H1V  A 501 ( 3.8A)
0.50A 3u5kD-6dneA:
23.4
3u5kD-6dneA:
undetectable