SIMILAR PATTERNS OF AMINO ACIDS FOR 3U5J_A_08HA1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1di6 MOLYBDENUM COFACTOR
BIOSYNTHETIC ENZYME


(Escherichia
coli)
PF00994
(MoCF_biosynth)
4 TRP A  31
LEU A  69
LEU A 128
ILE A 158
None
1.02A 3u5jA-1di6A:
undetectable
3u5jA-1di6A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ef4 DNA-DIRECTED RNA
POLYMERASE


(Methanothermobacter
thermautotrophicus)
PF01194
(RNA_pol_N)
4 PRO A  30
LEU A  37
LEU A  39
ILE A  49
None
0.92A 3u5jA-1ef4A:
undetectable
3u5jA-1ef4A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hkg HEXOKINASE A

(Saccharomyces
cerevisiae)
PF00349
(Hexokinase_1)
PF03727
(Hexokinase_2)
4 TRP A  51
PRO A  49
ILE A 225
MET A 240
None
1.03A 3u5jA-1hkgA:
undetectable
3u5jA-1hkgA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ikp EXOTOXIN A

(Pseudomonas
aeruginosa)
PF09009
(Exotox-A_cataly)
PF09101
(Exotox-A_bind)
PF09102
(Exotox-A_target)
4 TRP A 190
LEU A 199
LEU A 202
ILE A 132
None
0.83A 3u5jA-1ikpA:
undetectable
3u5jA-1ikpA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1im4 DBH

(Sulfolobus
solfataricus)
PF00817
(IMS)
PF11798
(IMS_HHH)
5 PRO A 185
LEU A 179
LEU A 176
ASN A 148
ILE A 150
None
1.31A 3u5jA-1im4A:
undetectable
3u5jA-1im4A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kfi PHOSPHOGLUCOMUTASE 1

(Paramecium
tetraurelia)
PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III)
4 LEU A 329
LEU A 357
ILE A 387
MET A 382
None
0.98A 3u5jA-1kfiA:
undetectable
3u5jA-1kfiA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kzh PHOSPHOFRUCTOKINASE

(Borreliella
burgdorferi)
PF00365
(PFK)
4 PRO A 202
LEU A 482
ASN A 211
ILE A 214
None
0.91A 3u5jA-1kzhA:
undetectable
3u5jA-1kzhA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oxj RNA-BINDING PROTEIN
SMAUG


(Drosophila
melanogaster)
PF00536
(SAM_1)
PF09246
(PHAT)
4 PRO A 688
LEU A 608
ILE A 601
MET A 598
None
0.93A 3u5jA-1oxjA:
undetectable
3u5jA-1oxjA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t6p PHENYLALANINE
AMMONIA-LYASE


(Rhodotorula
toruloides)
PF00221
(Lyase_aromatic)
4 PRO A 201
LEU A 139
ILE A 221
MET A 169
None
1.03A 3u5jA-1t6pA:
undetectable
3u5jA-1t6pA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tdf THIOREDOXIN
REDUCTASE


(Escherichia
coli)
PF07992
(Pyr_redox_2)
4 PRO A  53
LEU A  64
LEU A  43
ILE A 296
None
None
FAD  A 500 (-3.3A)
None
1.03A 3u5jA-1tdfA:
undetectable
3u5jA-1tdfA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ue8 367AA LONG
HYPOTHETICAL
CYTOCHROME P450


(Sulfurisphaera
tokodaii)
PF00067
(p450)
4 PRO A 123
LEU A 104
LEU A 105
ILE A 219
None
0.76A 3u5jA-1ue8A:
undetectable
3u5jA-1ue8A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vdc NADPH DEPENDENT
THIOREDOXIN
REDUCTASE


(Arabidopsis
thaliana)
PF07992
(Pyr_redox_2)
4 PRO A  53
LEU A  64
LEU A  43
ILE A 296
None
None
FAD  A 400 (-4.1A)
None
0.99A 3u5jA-1vdcA:
undetectable
3u5jA-1vdcA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vk9 CONSERVED
HYPOTHETICAL PROTEIN
TM1506


(Thermotoga
maritima)
PF08973
(TM1506)
4 PRO A  72
LEU A  42
LEU A  20
ILE A  75
None
None
UNL  A 201 ( 3.7A)
None
1.04A 3u5jA-1vk9A:
undetectable
3u5jA-1vk9A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z45 GAL10 BIFUNCTIONAL
PROTEIN


(Saccharomyces
cerevisiae)
PF01263
(Aldose_epim)
PF16363
(GDP_Man_Dehyd)
4 PRO A 531
LEU A 448
ASN A 674
ILE A 673
None
1.04A 3u5jA-1z45A:
undetectable
3u5jA-1z45A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bf6 EXO-ALPHA-SIALIDASE

(Clostridium
perfringens)
PF13088
(BNR_2)
4 PRO A 446
LEU A 371
ASN A 417
MET A 318
None
0.98A 3u5jA-2bf6A:
undetectable
3u5jA-2bf6A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c2y METHYLENETETRAHYDROF
OLATE
DEHYDROGENASE-METHEN
YLTETRAHYDROFOLATE
CYCLOHYDROLASE


(Mycobacterium
tuberculosis)
PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C)
4 LEU A 100
LEU A 104
ASN A  79
ILE A  82
None
0.88A 3u5jA-2c2yA:
undetectable
3u5jA-2c2yA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d1f THREONINE SYNTHASE

(Mycobacterium
tuberculosis)
PF00291
(PALP)
4 PRO A 243
LEU A 146
ASN A 197
ILE A 252
None
None
PLP  A 500 (-4.8A)
None
1.02A 3u5jA-2d1fA:
undetectable
3u5jA-2d1fA:
14.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2


(Homo sapiens)
PF00439
(Bromodomain)
7 TRP A  31
PRO A  32
LEU A  42
LEU A  44
ASN A  90
ILE A  96
MET A  99
None
0.33A 3u5jA-2dvrA:
20.5
3u5jA-2dvrA:
70.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e6m WERNER SYNDROME
ATP-DEPENDENT
HELICASE HOMOLOG


(Mus musculus)
PF01612
(DNA_pol_A_exo1)
4 PRO A 115
LEU A 122
ILE A 108
MET A 111
None
0.99A 3u5jA-2e6mA:
undetectable
3u5jA-2e6mA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eql HORSE MILK LYSOZYME

(Equus caballus)
PF00062
(Lys)
4 TRP A  28
LEU A  59
LEU A  83
ILE A  92
None
1.02A 3u5jA-2eqlA:
undetectable
3u5jA-2eqlA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f4z TGTWINSCAN_2721 - E2
DOMAIN


(Toxoplasma
gondii)
PF00179
(UQ_con)
4 PRO A 109
LEU A  37
ILE A  98
MET A 111
None
0.95A 3u5jA-2f4zA:
undetectable
3u5jA-2f4zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gsk VITAMIN B12
TRANSPORTER BTUB


(Escherichia
coli)
PF00593
(TonB_dep_Rec)
PF07715
(Plug)
4 PRO A 412
LEU A 401
LEU A 398
ASN A 362
None
0.81A 3u5jA-2gskA:
undetectable
3u5jA-2gskA:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h6c CHLOROPHENOL
REDUCTION GENE K


(Desulfitobacterium
dehalogenans)
PF13545
(HTH_Crp_2)
4 LEU A 222
LEU A 219
ILE A 174
MET A 176
None
1.03A 3u5jA-2h6cA:
undetectable
3u5jA-2h6cA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iqf CATALASE

(Helicobacter
pylori)
PF00199
(Catalase)
PF06628
(Catalase-rel)
4 TRP A 179
PRO A 132
LEU A 291
ILE A 283
None
None
MHO  A 292 ( 4.1A)
None
1.04A 3u5jA-2iqfA:
undetectable
3u5jA-2iqfA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ixn SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
ACTIVATOR 2


(Saccharomyces
cerevisiae)
PF03095
(PTPA)
4 TRP A 266
PRO A 216
LEU A 250
ILE A 260
None
0.95A 3u5jA-2ixnA:
undetectable
3u5jA-2ixnA:
18.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3


(Mus musculus)
PF00439
(Bromodomain)
7 TRP A  57
PRO A  58
LEU A  68
LEU A  70
ASN A 116
ILE A 122
MET A 125
None
1.01A 3u5jA-2l5eA:
17.4
3u5jA-2l5eA:
77.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lav VACCINIA-RELATED
KINASE 1


(Homo sapiens)
PF00069
(Pkinase)
5 PRO A 296
LEU A 155
LEU A 324
ILE A 299
MET A 286
None
1.47A 3u5jA-2lavA:
undetectable
3u5jA-2lavA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okc TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN


(Bacteroides
thetaiotaomicron)
PF02384
(N6_Mtase)
PF12161
(HsdM_N)
4 PRO A 177
LEU A 185
ILE A 256
MET A 292
None
0.94A 3u5jA-2okcA:
undetectable
3u5jA-2okcA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p2m ACETYL-COENZYME A
SYNTHETASE


(Salmonella
enterica)
PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
PF16177
(ACAS_N)
4 PRO A 143
LEU A 317
LEU A 321
ILE A 108
None
1.05A 3u5jA-2p2mA:
undetectable
3u5jA-2p2mA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pfy PUTATIVE EXPORTED
PROTEIN


(Bordetella
pertussis)
PF03480
(DctP)
4 PRO A  83
LEU A 269
ILE A 276
MET A 280
None
0.94A 3u5jA-2pfyA:
undetectable
3u5jA-2pfyA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r0v CHROMATIN
STRUCTURE-REMODELING
COMPLEX PROTEIN RSC4


(Saccharomyces
cerevisiae)
PF00439
(Bromodomain)
4 PRO A 212
LEU A 222
ASN A 268
ILE A 274
None
0.86A 3u5jA-2r0vA:
12.7
3u5jA-2r0vA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v7b BENZOATE-COENZYME A
LIGASE


(Paraburkholderia
xenovorans)
PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
4 LEU A  65
LEU A  68
ILE A 125
MET A  80
None
0.88A 3u5jA-2v7bA:
undetectable
3u5jA-2v7bA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2whd THIOREDOXIN
REDUCTASE


(Hordeum vulgare)
PF07992
(Pyr_redox_2)
4 PRO A  63
LEU A  74
LEU A  53
ILE A 303
None
None
FAD  A 400 (-4.0A)
None
1.01A 3u5jA-2whdA:
undetectable
3u5jA-2whdA:
16.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2wp1 BROMODOMAIN
TESTIS-SPECIFIC
PROTEIN


(Mus musculus)
PF00439
(Bromodomain)
6 TRP A 292
PRO A 293
LEU A 303
LEU A 305
ASN A 351
MET A 360
None
0.70A 3u5jA-2wp1A:
16.7
3u5jA-2wp1A:
38.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xax RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
SUBUNIT ALPHA


(Escherichia
coli)
PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC)
PF03477
(ATP-cone)
4 LEU A 719
ASN A 416
ILE A 339
MET A 308
None
1.04A 3u5jA-2xaxA:
2.9
3u5jA-2xaxA:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xij METHYLMALONYL-COA
MUTASE,
MITOCHONDRIAL


(Homo sapiens)
PF01642
(MM_CoA_mutase)
PF02310
(B12-binding)
4 LEU A 549
ASN A 219
ILE A 217
MET A 186
None
0.99A 3u5jA-2xijA:
undetectable
3u5jA-2xijA:
9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xwg SORTASE

(Actinomyces
oris)
PF04203
(Sortase)
4 PRO A 191
LEU A 263
ILE A 169
MET A 155
None
1.00A 3u5jA-2xwgA:
undetectable
3u5jA-2xwgA:
18.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2yek BROMODOMAIN-CONTAINI
NG PROTEIN 2


(Homo sapiens)
PF00439
(Bromodomain)
7 TRP A  97
PRO A  98
LEU A 108
LEU A 110
ASN A 156
ILE A 162
MET A 165
None
EAM  A1188 (-4.6A)
EAM  A1188 ( 3.8A)
EAM  A1188 (-4.5A)
EAM  A1188 (-3.2A)
EAM  A1188 (-3.8A)
EAM  A1188 ( 4.1A)
0.47A 3u5jA-2yekA:
20.4
3u5jA-2yekA:
70.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z7x TOLL-LIKE RECEPTOR
1, VARIABLE
LYMPHOCYTE RECEPTOR
B


(Eptatretus
burgeri;
Homo sapiens)
PF11921
(DUF3439)
PF13855
(LRR_8)
4 PRO B  40
LEU B  68
LEU B  71
ILE B  52
None
0.96A 3u5jA-2z7xB:
undetectable
3u5jA-2z7xB:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zzg ALANYL-TRNA
SYNTHETASE


(Pyrococcus
horikoshii)
PF01411
(tRNA-synt_2c)
PF07973
(tRNA_SAD)
4 LEU A 310
LEU A 313
ASN A 295
ILE A 332
None
0.94A 3u5jA-2zzgA:
undetectable
3u5jA-2zzgA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d8x THIOREDOXIN
REDUCTASE 1


(Saccharomyces
cerevisiae)
PF07992
(Pyr_redox_2)
4 PRO A  56
LEU A  67
LEU A  46
ILE A 298
None
None
FAD  A1001 (-4.3A)
None
1.01A 3u5jA-3d8xA:
undetectable
3u5jA-3d8xA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ef1 RNA POLYMERASE II
SUBUNIT A C-TERMINAL
DOMAIN PHOSPHATASE


(Schizosaccharomyces
pombe)
PF03031
(NIF)
PF12738
(PTCB-BRCT)
4 PRO A 417
LEU A 438
LEU A 439
ILE A 321
None
0.98A 3u5jA-3ef1A:
undetectable
3u5jA-3ef1A:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE


(Glutamicibacter
protophormiae)
PF03644
(Glyco_hydro_85)
4 TRP A 204
LEU A 138
LEU A 135
ILE A 214
None
1.00A 3u5jA-3fhaA:
undetectable
3u5jA-3fhaA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iyj MAJOR CAPSID PROTEIN
L1


(Deltapapillomavirus
4)
no annotation 4 LEU F 389
LEU F 392
ASN F 317
ILE F 320
None
1.04A 3u5jA-3iyjF:
undetectable
3u5jA-3iyjF:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jwj HEN1

(Trichormus
variabilis)
PF08242
(Methyltransf_12)
4 LEU A 324
LEU A 327
ILE A 297
MET A 269
None
0.95A 3u5jA-3jwjA:
undetectable
3u5jA-3jwjA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m16 TRANSALDOLASE

(Oleispira
antarctica)
PF00923
(TAL_FSA)
4 PRO A 184
LEU A 243
LEU A 270
ILE A 216
None
0.92A 3u5jA-3m16A:
undetectable
3u5jA-3m16A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n1b VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 54


(Mus musculus)
PF07928
(Vps54)
4 LEU A 959
LEU A 962
ILE A 917
MET A 865
None
0.82A 3u5jA-3n1bA:
undetectable
3u5jA-3n1bA:
18.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3nxb CAT EYE SYNDROME
CRITICAL REGION
PROTEIN 2


(Homo sapiens)
PF00439
(Bromodomain)
4 TRP A 457
PRO A 458
ASN A 514
MET A 523
None
None
EDO  A   1 (-3.3A)
None
0.46A 3u5jA-3nxbA:
16.2
3u5jA-3nxbA:
32.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pr2 TRYPTOPHAN SYNTHASE
ALPHA CHAIN
TRYPTOPHAN SYNTHASE
BETA CHAIN


(Salmonella
enterica)
PF00290
(Trp_syntA)
PF00291
(PALP)
4 PRO B  18
LEU A 162
ASN A 157
ILE B  20
F9F  A   1 (-4.1A)
None
None
None
0.96A 3u5jA-3pr2B:
undetectable
3u5jA-3pr2B:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r3q SUPPRESSOR PROTEIN
STP22 OF
TEMPERATURE-SENSITIV
E ALPHA-FACTOR
RECEPTOR AND
ARGININE PERMEASE


(Saccharomyces
cerevisiae)
PF05743
(UEV)
4 PRO A  96
LEU A  38
LEU A  45
ILE A  98
None
1.04A 3u5jA-3r3qA:
undetectable
3u5jA-3r3qA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s6d PUTATIVE
TRIOSEPHOSPHATE
ISOMERASE


(Coccidioides
immitis)
PF00121
(TIM)
4 PRO A  11
LEU A  55
LEU A  17
ILE A 154
None
0.96A 3u5jA-3s6dA:
undetectable
3u5jA-3s6dA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3soz CYTOPLASMIC PROTEIN
STM1381


(Salmonella
enterica)
PF07090
(GATase1_like)
4 LEU A  98
LEU A 134
ILE A   6
MET A  49
None
1.00A 3u5jA-3sozA:
undetectable
3u5jA-3sozA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vti HYDROGENASE
MATURATION FACTOR


(Caldanaerobacter
subterraneus)
PF00586
(AIRS)
PF02769
(AIRS_C)
4 PRO C 237
LEU C 217
LEU C 220
ILE C 186
None
0.93A 3u5jA-3vtiC:
undetectable
3u5jA-3vtiC:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wiw GLYCOSYL HYDROLASE
FAMILY 88


(Pedobacter
heparinus)
PF07470
(Glyco_hydro_88)
4 PRO A 290
LEU A 340
LEU A 337
ILE A 312
None
0.84A 3u5jA-3wiwA:
undetectable
3u5jA-3wiwA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wpe TOLL-LIKE RECEPTOR 9

(Bos taurus)
PF13516
(LRR_6)
PF13855
(LRR_8)
4 TRP A 302
LEU A 314
LEU A 340
ILE A 328
None
0.98A 3u5jA-3wpeA:
undetectable
3u5jA-3wpeA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aq9 ACETYLCHOLINE
RECEPTOR GAMMA
SUBUNIT


(Torpedo
marmorata)
PF02931
(Neur_chan_LBD)
PF02932
(Neur_chan_memb)
4 TRP E  85
PRO E  87
LEU E 157
ILE E  57
None
1.00A 3u5jA-4aq9E:
undetectable
3u5jA-4aq9E:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bjt DNA-BINDING PROTEIN
RAP1


(Saccharomyces
cerevisiae)
PF11626
(Rap1_C)
4 PRO A 766
LEU A 758
LEU A 755
ILE A 724
None
0.95A 3u5jA-4bjtA:
undetectable
3u5jA-4bjtA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f4w DNA POLYMERASE IV

(Sulfolobus
acidocaldarius;
Sulfolobus
solfataricus)
PF00817
(IMS)
PF11798
(IMS_HHH)
5 PRO A 185
LEU A 179
LEU A 176
ASN A 148
ILE A 150
None
1.40A 3u5jA-4f4wA:
undetectable
3u5jA-4f4wA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fcg UNCHARACTERIZED
PROTEIN


(Xanthomonas
euvesicatoria)
PF13855
(LRR_8)
4 PRO A 289
LEU A 285
LEU A 261
ILE A 268
None
1.02A 3u5jA-4fcgA:
undetectable
3u5jA-4fcgA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gud IMIDAZOLE GLYCEROL
PHOSPHATE SYNTHASE
SUBUNIT HISH


(Vibrio cholerae)
PF00117
(GATase)
4 PRO A  47
LEU A  84
LEU A 103
ILE A   8
None
0.97A 3u5jA-4gudA:
undetectable
3u5jA-4gudA:
18.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hbx BROMODOMAIN-CONTAINI
NG PROTEIN 4


(Homo sapiens)
PF00439
(Bromodomain)
7 TRP A  81
PRO A  82
LEU A  92
LEU A  94
ASN A 140
ILE A 146
MET A 149
None
14X  A 201 (-4.4A)
14X  A 201 (-4.4A)
None
14X  A 201 (-3.1A)
14X  A 201 ( 4.0A)
14X  A 201 (-3.5A)
0.37A 3u5jA-4hbxA:
25.2
3u5jA-4hbxA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hwi BAG FAMILY MOLECULAR
CHAPERONE REGULATOR
1


(Arabidopsis
thaliana)
PF02179
(BAG)
PF14560
(Ubiquitin_2)
4 PRO B  98
LEU B 134
LEU B 108
ILE B  80
None
0.83A 3u5jA-4hwiB:
2.4
3u5jA-4hwiB:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hyk DNA POLYMERASE IV

(Sulfolobus
acidocaldarius)
PF00817
(IMS)
PF11798
(IMS_HHH)
4 PRO A 185
LEU A 176
ASN A 148
ILE A 150
None
0.99A 3u5jA-4hykA:
undetectable
3u5jA-4hykA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hzu ENERGY-COUPLING
FACTOR TRANSPORTER
ATP-BINDING PROTEIN
ECFA 1


(Lactobacillus
brevis)
PF00005
(ABC_tran)
4 PRO B  59
LEU B  80
LEU B  83
ILE B  64
None
0.82A 3u5jA-4hzuB:
undetectable
3u5jA-4hzuB:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i1t RNA-DIRECTED RNA
POLYMERASE L


(Cali
mammarenavirus)
PF17296
(ArenaCapSnatch)
4 PRO A  87
LEU A 125
LEU A 129
ILE A  71
None
0.88A 3u5jA-4i1tA:
3.1
3u5jA-4i1tA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4irn PROLYL-ACP
DEHYDROGENASE


([Oscillatoria]
sp. PCC 6506)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
4 PRO A  54
LEU A  76
ASN A  90
ILE A  93
None
0.96A 3u5jA-4irnA:
2.3
3u5jA-4irnA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A


(Mus musculus)
PF13516
(LRR_6)
4 LEU A 445
LEU A 441
ASN A 496
ILE A 493
None
1.04A 3u5jA-4k17A:
undetectable
3u5jA-4k17A:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o9d RIK1-ASSOCIATED
FACTOR 1


(Schizosaccharomyces
pombe)
no annotation 4 PRO B 339
LEU B 366
LEU B 354
ILE B 343
None
0.94A 3u5jA-4o9dB:
undetectable
3u5jA-4o9dB:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6p CONSERVED
HYPOTHETICAL
SECRETED PROTEIN


(Helicobacter
pylori)
PF17033
(Peptidase_M99)
PF17129
(Peptidase_M99_C)
PF17130
(Peptidase_M99_m)
4 LEU A 283
LEU A 271
ASN A  57
ILE A 312
None
0.92A 3u5jA-4q6pA:
undetectable
3u5jA-4q6pA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r9g MBP1

(Caldanaerobius
polysaccharolyticus)
PF13416
(SBP_bac_8)
4 TRP A  25
PRO A  24
LEU A  21
LEU A  82
BMA  A 503 ( 4.1A)
None
None
None
0.89A 3u5jA-4r9gA:
undetectable
3u5jA-4r9gA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rnz CONSERVED
HYPOTHETICAL
SECRETED PROTEIN


(Helicobacter
pylori)
PF01551
(Peptidase_M23)
4 TRP A  46
LEU A  55
LEU A  64
ILE A 108
None
1.03A 3u5jA-4rnzA:
undetectable
3u5jA-4rnzA:
16.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4uyd BROMODOMAIN-CONTAINI
NG PROTEIN 4


(Homo sapiens)
PF00439
(Bromodomain)
7 TRP A  81
PRO A  82
LEU A  92
LEU A  94
ASN A 140
ILE A 146
MET A 149
None
V1T  A1171 (-4.2A)
V1T  A1171 (-3.8A)
None
V1T  A1171 (-3.1A)
DMS  A1169 ( 4.3A)
DMS  A1169 ( 3.8A)
0.14A 3u5jA-4uydA:
25.8
3u5jA-4uydA:
92.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4uyg BROMODOMAIN-CONTAINI
NG PROTEIN 2


(Homo sapiens)
PF00439
(Bromodomain)
6 TRP A 370
PRO A 371
LEU A 381
LEU A 383
ASN A 429
MET A 438
None
None
73B  A1456 (-4.9A)
73B  A1456 (-4.9A)
73B  A1456 (-3.3A)
73B  A1456 ( 3.8A)
0.53A 3u5jA-4uygA:
17.8
3u5jA-4uygA:
34.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xpz RNA POLYMERASE II
SUBUNIT A C-TERMINAL
DOMAIN PHOSPHATASE


(Schizosaccharomyces
pombe)
PF03031
(NIF)
PF12738
(PTCB-BRCT)
4 PRO A 355
LEU A 376
LEU A 377
ILE A 321
PG4  A 603 (-4.5A)
None
None
None
0.94A 3u5jA-4xpzA:
undetectable
3u5jA-4xpzA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z61 PHYTOSULFOKINE
RECEPTOR 1


(Daucus carota)
PF00560
(LRR_1)
PF13855
(LRR_8)
4 TRP A 444
PRO A 442
LEU A 454
ASN A 459
None
1.03A 3u5jA-4z61A:
undetectable
3u5jA-4z61A:
11.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4z93 BROMODOMAIN-CONTAINI
NG PROTEIN 4


(Homo sapiens)
PF00439
(Bromodomain)
6 TRP A 374
PRO A 375
LEU A 385
LEU A 387
ASN A 433
MET A 442
4LD  A 501 (-3.9A)
4LD  A 501 (-3.9A)
4LD  A 501 (-4.1A)
4LD  A 501 (-4.4A)
4LD  A 501 (-2.8A)
4LD  A 501 ( 3.4A)
0.44A 3u5jA-4z93A:
17.7
3u5jA-4z93A:
36.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b7c S-CRYSTALLIN OCTVUS4

(Octopus
vulgaris)
PF02798
(GST_N)
PF14497
(GST_C_3)
4 PRO A 176
LEU A 184
LEU A 190
ILE A  99
None
1.03A 3u5jA-5b7cA:
undetectable
3u5jA-5b7cA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b86 TUMOR NECROSIS
FACTOR ALPHA-INDUCED
PROTEIN 2


(Mus musculus)
PF06046
(Sec6)
4 PRO A 289
LEU A 295
LEU A 300
ILE A 285
None
1.03A 3u5jA-5b86A:
undetectable
3u5jA-5b86A:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gnc AVH146

(Phytophthora
sojae)
no annotation 4 TRP A 572
LEU A 623
LEU A 607
ILE A 563
None
1.02A 3u5jA-5gncA:
undetectable
3u5jA-5gncA:
12.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5hjc BROMODOMAIN-CONTAINI
NG PROTEIN 3


(Homo sapiens)
PF00439
(Bromodomain)
6 TRP A 332
PRO A 333
LEU A 343
LEU A 345
ASN A 391
MET A 400
None
0.58A 3u5jA-5hjcA:
17.9
3u5jA-5hjcA:
39.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ikf CHROMATIN REMODELING
FACTOR MIT1


(Schizosaccharomyces
pombe)
no annotation 4 PRO A1275
LEU A1286
LEU A1330
ILE A1279
None
0.99A 3u5jA-5ikfA:
undetectable
3u5jA-5ikfA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iz3 PREDICTED PROTEIN

(Physcomitrella
patens)
PF00316
(FBPase)
4 PRO B 298
LEU B 332
LEU B 335
ILE B 219
None
1.04A 3u5jA-5iz3B:
undetectable
3u5jA-5iz3B:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5izh RNA-DIRECTED RNA
POLYMERASE L


(Lassa
mammarenavirus)
PF17296
(ArenaCapSnatch)
4 PRO A  88
LEU A 126
LEU A 130
ILE A  72
None
0.82A 3u5jA-5izhA:
4.6
3u5jA-5izhA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k9h 0940_GH29

(unidentified)
PF00754
(F5_F8_type_C)
PF01120
(Alpha_L_fucos)
4 TRP A 188
LEU A 146
LEU A 150
ILE A 204
None
0.85A 3u5jA-5k9hA:
undetectable
3u5jA-5k9hA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lc5 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4


(Bos taurus)
PF00361
(Proton_antipo_M)
PF01059
(Oxidored_q5_N)
4 LEU M 351
LEU M 352
ASN M 333
ILE M 337
None
1.01A 3u5jA-5lc5M:
undetectable
3u5jA-5lc5M:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lst ATP-DEPENDENT DNA
HELICASE Q4


(Homo sapiens)
PF00270
(DEAD)
PF00271
(Helicase_C)
4 PRO A 597
LEU A 528
LEU A 579
ILE A 569
None
1.04A 3u5jA-5lstA:
undetectable
3u5jA-5lstA:
10.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5n15 BROMODOMAIN-CONTAINI
NG FACTOR 1


(Candida
albicans)
PF00439
(Bromodomain)
5 PRO A 233
LEU A 243
ASN A 291
ILE A 297
MET A 300
IOD  A 405 ( 4.4A)
None
IOD  A 404 (-3.9A)
IOD  A 404 ( 4.8A)
None
0.66A 3u5jA-5n15A:
18.5
3u5jA-5n15A:
35.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5u6v BROMODOMAIN-CONTAINI
NG PROTEIN 2


(Homo sapiens)
no annotation 6 TRP A 370
PRO A 371
LEU A 381
LEU A 383
ASN A 429
MET A 438
None
7WY  A 501 (-4.4A)
7WY  A 501 (-4.9A)
None
7WY  A 501 (-3.4A)
7WY  A 501 ( 3.9A)
0.39A 3u5jA-5u6vA:
17.9
3u5jA-5u6vA:
40.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uib OXIDOREDUCTASE
PROTEIN


(Agrobacterium
tumefaciens)
PF01408
(GFO_IDH_MocA)
4 PRO A 242
LEU A 179
ASN A 126
ILE A 291
None
TLA  A 402 (-4.0A)
NAD  A 401 (-3.0A)
NAD  A 401 ( 4.7A)
0.98A 3u5jA-5uibA:
undetectable
3u5jA-5uibA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5usx THIOREDOXIN
REDUCTASE


(Vibrio
vulnificus)
PF07992
(Pyr_redox_2)
4 PRO A  54
LEU A  65
LEU A  44
ILE A 296
None
None
FAD  A 402 (-4.1A)
None
1.04A 3u5jA-5usxA:
undetectable
3u5jA-5usxA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v84 CAT EYE SYNDROME
CRITICAL REGION
PROTEIN 2


(Homo sapiens)
PF00439
(Bromodomain)
4 TRP A 457
PRO A 458
ASN A 514
MET A 523
None
96V  A 602 (-4.5A)
96V  A 602 (-2.6A)
None
0.41A 3u5jA-5v84A:
16.2
3u5jA-5v84A:
28.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5vbr BROMODOMAIN
TESTIS-SPECIFIC
PROTEIN


(Homo sapiens)
no annotation 7 TRP A  50
PRO A  51
LEU A  61
LEU A  63
ASN A 109
ILE A 115
MET A 118
CL  A 208 (-4.9A)
IBI  A 201 (-4.3A)
IBI  A 201 (-4.2A)
IBI  A 201 (-4.9A)
IBI  A 201 (-3.3A)
IBI  A 201 ( 3.8A)
None
0.48A 3u5jA-5vbrA:
19.3
3u5jA-5vbrA:
68.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x7k LIPASE B

(Serratia
marcescens)
no annotation 4 LEU A 443
LEU A 482
ILE A 510
MET A 532
None
0.99A 3u5jA-5x7kA:
undetectable
3u5jA-5x7kA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xbl CRISPR-ASSOCIATED
ENDONUCLEASE
CAS9/CSN1


(Streptococcus
pyogenes)
PF13395
(HNH_4)
PF16592
(Cas9_REC)
PF16593
(Cas9-BH)
PF16595
(Cas9_PI)
4 PRO A 871
LEU A 908
ASN A 854
ILE A 841
None
1.01A 3u5jA-5xblA:
undetectable
3u5jA-5xblA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xfa NAD-REDUCING
HYDROGENASE


(Hydrogenophilus
thermoluteolus)
PF01257
(2Fe-2S_thioredx)
PF01512
(Complex1_51K)
PF10589
(NADH_4Fe-4S)
4 LEU A 102
ASN A 122
ILE A 121
MET A 126
None
0.90A 3u5jA-5xfaA:
undetectable
3u5jA-5xfaA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyi 40S RIBOSOMAL
PROTEIN S21


(Trichomonas
vaginalis)
PF01249
(Ribosomal_S21e)
4 LEU V  77
LEU V  78
ILE V  71
MET V  18
None
0.99A 3u5jA-5xyiV:
undetectable
3u5jA-5xyiV:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zvs VP2

(Aquareovirus C)
no annotation 4 PRO 2 183
LEU 2 160
LEU 2 157
ILE 2  52
None
1.00A 3u5jA-5zvs2:
undetectable
3u5jA-5zvs2:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bja ACETYL-COA
ACETYLTRANSFERASE A


(Ascaris suum)
no annotation 4 PRO A 296
LEU A 334
LEU A 336
ILE A 319
None
1.03A 3u5jA-6bjaA:
undetectable
3u5jA-6bjaA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dne BROMODOMAIN-CONTAINI
NG PROTEIN 4


(Homo sapiens)
no annotation 7 TRP A  81
PRO A  82
LEU A  92
LEU A  94
ASN A 140
ILE A 146
MET A 149
None
H1V  A 501 (-4.6A)
H1V  A 501 (-4.2A)
H1V  A 501 (-4.7A)
H1V  A 501 (-3.2A)
H1V  A 501 (-3.8A)
H1V  A 501 ( 3.8A)
0.42A 3u5jA-6dneA:
23.4
3u5jA-6dneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fnw VOLUME-REGULATED
ANION CHANNEL
SUBUNIT LRRC8A


(Mus musculus)
no annotation 4 PRO A 509
LEU A 515
LEU A 518
ILE A 500
None
0.87A 3u5jA-6fnwA:
undetectable
3u5jA-6fnwA:
25.00