SIMILAR PATTERNS OF AMINO ACIDS FOR 3TYE_B_YTZB902_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ajz DIHYDROPTEROATE
SYNTHASE

(Escherichia
coli) 		PF00809
(Pterin_bind) 		3 PHE A 190
LYS A 221
SER A 222
 None
SO4  A 283 ( 4.2A)
SO4  A 284 (-2.7A)
 0.69A 3tyeB-1ajzA:
35.7		 3tyeB-1ajzA:
38.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cp9 PENICILLIN G AMIDASE

(Providencia
rettgeri) 		PF01804
(Penicil_amidase) 		3 PHE B 302
LYS B 404
SER B 405
 None
 1.08A 3tyeB-1cp9B:
undetectable		 3tyeB-1cp9B:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gz0 HYPOTHETICAL
TRNA/RRNA
METHYLTRANSFERASE
YJFH

(Escherichia
coli) 		PF00588
(SpoU_methylase)
PF08032
(SpoU_sub_bind) 		3 PHE A  26
LYS A  61
SER A  62
 None
 1.23A 3tyeB-1gz0A:
undetectable		 3tyeB-1gz0A:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hlg LIPASE, GASTRIC

(Homo sapiens) 		PF00561
(Abhydrolase_1) 		3 PHE A 273
LYS A 280
SER A 281
 None
 0.89A 3tyeB-1hlgA:
undetectable		 3tyeB-1hlgA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kve SMK TOXIN

(Millerozyma
farinosa) 		no annotation 3 PHE A  43
LYS B 167
SER B 166
 None
 1.28A 3tyeB-1kveA:
undetectable		 3tyeB-1kveA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ni3 YCHF GTP-BINDING
PROTEIN

(Schizosaccharomyces
pombe) 		PF01926
(MMR_HSR1)
PF06071
(YchF-GTPase_C) 		3 PHE A 109
LYS A  33
SER A  34
 None
SO4  A 393 (-3.0A)
SO4  A 393 (-3.3A)
 1.35A 3tyeB-1ni3A:
2.8		 3tyeB-1ni3A:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ogy PERIPLASMIC NITRATE
REDUCTASE

(Rhodobacter
sphaeroides) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		3 PHE A 595
LYS A 541
SER A 540
 None
 1.23A 3tyeB-1ogyA:
undetectable		 3tyeB-1ogyA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1on9 METHYLMALONYL-COA
CARBOXYLTRANSFERASE
12S SUBUNIT

(Propionibacterium
freudenreichii) 		PF01039
(Carboxyl_trans) 		3 PHE A 105
LYS A  38
SER A  41
 MCA  A4001 (-4.4A)
None
None
 1.36A 3tyeB-1on9A:
undetectable		 3tyeB-1on9A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p74 SHIKIMATE
5-DEHYDROGENASE

(Haemophilus
influenzae) 		PF01488
(Shikimate_DH)
PF08501
(Shikimate_dh_N) 		3 PHE A 239
LYS A  15
SER A  16
 None
 1.20A 3tyeB-1p74A:
undetectable		 3tyeB-1p74A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1slq VP4

(Rotavirus A) 		PF17477
(Rota_VP4_MID)
PF17478
(VP4_helical) 		3 PHE A 326
LYS A 346
SER A 349
 None
 1.28A 3tyeB-1slqA:
undetectable		 3tyeB-1slqA:
17.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tww DHPS,
DIHYDROPTEROATE
SYNTHASE

(Bacillus
anthracis) 		PF00809
(Pterin_bind) 		3 PHE A 189
LYS A 220
SER A 221
 HH2  A 282 (-4.8A)
HH2  A 282 (-2.9A)
SO4  A 281 (-3.7A)
 0.51A 3tyeB-1twwA:
45.5		 3tyeB-1twwA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1txz HYPOTHETICAL 32.1
KDA PROTEIN IN
ADH3-RCA1 INTERGENIC
REGION

(Saccharomyces
cerevisiae) 		PF14519
(Macro_2) 		3 PHE A 264
LYS A 207
SER A 208
 None
 1.26A 3tyeB-1txzA:
undetectable		 3tyeB-1txzA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wba WINGED BEAN ALBUMIN
1

(Psophocarpus
tetragonolobus) 		PF00197
(Kunitz_legume) 		3 PHE A  97
LYS A 105
SER A  93
 None
 1.09A 3tyeB-1wbaA:
undetectable		 3tyeB-1wbaA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wuf HYPOTHETICAL PROTEIN
LIN2664

(Listeria
innocua) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 PHE A1051
LYS A1029
SER A1028
 None
 1.35A 3tyeB-1wufA:
6.5		 3tyeB-1wufA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xk8 DIVALENT CATION
TOLERANT PROTEIN
CUTA

(Homo sapiens) 		PF03091
(CutA1) 		3 PHE A 135
LYS A  40
SER A  44
 None
 1.11A 3tyeB-1xk8A:
undetectable		 3tyeB-1xk8A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a2l UNKNOWN

(Klebsiella
pneumoniae) 		PF03928
(Haem_degrading) 		3 PHE A 105
LYS A  67
SER A  70
 None
 0.92A 3tyeB-2a2lA:
undetectable		 3tyeB-2a2lA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b1h FAB 2219, HEAVY
CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 PHE H 148
LYS H  13
SER H  14
 None
 1.23A 3tyeB-2b1hH:
undetectable		 3tyeB-2b1hH:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b39 C3

(Bos taurus) 		PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl) 		3 PHE A1058
LYS A1430
SER A1429
 None
 0.90A 3tyeB-2b39A:
undetectable		 3tyeB-2b39A:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b4i OUTER CAPSID PROTEIN
VP4

(Rotavirus A) 		PF17477
(Rota_VP4_MID) 		3 PHE A 326
LYS A 346
SER A 349
 None
 1.37A 3tyeB-2b4iA:
undetectable		 3tyeB-2b4iA:
26.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bp1 AFLATOXIN B1
ALDEHYDE REDUCTASE
MEMBER 2

(Homo sapiens) 		PF00248
(Aldo_ket_red) 		3 PHE A  76
LYS A 113
SER A 114
 None
 1.25A 3tyeB-2bp1A:
6.0		 3tyeB-2bp1A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c7z 3-KETOACYL-COA
THIOLASE 2

(Arabidopsis
thaliana) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		3 PHE A 186
LYS A  66
SER A  65
 None
 0.96A 3tyeB-2c7zA:
undetectable		 3tyeB-2c7zA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c91 AFLATOXIN B1
ALDEHYDE REDUCTASE
MEMBER 2

(Mus musculus) 		PF00248
(Aldo_ket_red) 		3 PHE A  43
LYS A  80
SER A  81
 None
 1.23A 3tyeB-2c91A:
9.4		 3tyeB-2c91A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2db3 ATP-DEPENDENT RNA
HELICASE VASA

(Drosophila
melanogaster) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		3 PHE A 343
LYS A 262
SER A 263
 None
 1.05A 3tyeB-2db3A:
undetectable		 3tyeB-2db3A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2frv PERIPLASMIC
HYDROGENASE

(Desulfovibrio
gigas) 		no annotation 3 PHE L 252
LYS L 144
SER L 142
 None
 1.33A 3tyeB-2frvL:
undetectable		 3tyeB-2frvL:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i00 ACETYLTRANSFERASE,
GNAT FAMILY

(Enterococcus
faecalis) 		PF13527
(Acetyltransf_9)
PF13530
(SCP2_2) 		3 PHE A 207
LYS A  53
SER A  52
 None
 0.96A 3tyeB-2i00A:
undetectable		 3tyeB-2i00A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iy9 SUBA

(Escherichia
coli) 		PF00082
(Peptidase_S8) 		3 PHE A  78
LYS A  68
SER A 114
 None
 1.32A 3tyeB-2iy9A:
undetectable		 3tyeB-2iy9A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pn0 PROKARYOTIC
TRANSCRIPTION
ELONGATION FACTOR
GREA/GREB

(Nitrosomonas
europaea) 		PF01272
(GreA_GreB)
PF14760
(Rnk_N) 		3 PHE A  63
LYS A  74
SER A  59
 None
OCS  A  73 ( 3.5A)
None
 1.35A 3tyeB-2pn0A:
undetectable		 3tyeB-2pn0A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pyu INOSINE TRIPHOSPHATE
PYROPHOSPHATASE RDGB

(Escherichia
coli) 		PF01725
(Ham1p_like) 		3 PHE A 154
LYS A 177
SER A 178
 IMP  A3036 (-3.8A)
IMP  A3036 (-2.7A)
None
 1.25A 3tyeB-2pyuA:
undetectable		 3tyeB-2pyuA:
26.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x1i 4-ALPHA-GLUCANOTRANS
FERASE

(Thermus
brockianus) 		PF02446
(Glyco_hydro_77) 		3 PHE A  62
LYS A 148
SER A 149
 None
 1.21A 3tyeB-2x1iA:
8.2		 3tyeB-2x1iA:
19.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2y5j DIHYDROPTEROATE
SYNTHASE

(Burkholderia
cenocepacia) 		PF00809
(Pterin_bind) 		3 PHE A 196
LYS A 233
SER A 234
 None
 0.44A 3tyeB-2y5jA:
33.0		 3tyeB-2y5jA:
37.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z6k REPLICATION PROTEIN
A 32 KDA SUBUNIT

(Homo sapiens) 		PF08784
(RPA_C) 		3 PHE A  64
LYS A 139
SER A 140
 None
 1.34A 3tyeB-2z6kA:
undetectable		 3tyeB-2z6kA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zqp PREPROTEIN
TRANSLOCASE SECY
SUBUNIT

(Thermus
thermophilus) 		PF00344
(SecY) 		3 PHE Y 331
LYS Y 102
SER Y 101
 None
 1.12A 3tyeB-2zqpY:
undetectable		 3tyeB-2zqpY:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bfj 1,3-PROPANEDIOL
OXIDOREDUCTASE

(Klebsiella
pneumoniae) 		PF00465
(Fe-ADH) 		3 PHE A 368
LYS A 210
SER A 209
 None
 0.83A 3tyeB-3bfjA:
2.4		 3tyeB-3bfjA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c12 FLAGELLAR PROTEIN

(Xanthomonas
campestris) 		PF13860
(FlgD_ig)
PF13861
(FLgD_tudor) 		3 PHE A  89
LYS A 147
SER A 148
 None
 1.16A 3tyeB-3c12A:
undetectable		 3tyeB-3c12A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c8z CYSTEINYL-TRNA
SYNTHETASE

(Mycolicibacterium
smegmatis) 		PF01406
(tRNA-synt_1e) 		3 PHE A 185
LYS A 197
SER A 198
 None
 1.09A 3tyeB-3c8zA:
undetectable		 3tyeB-3c8zA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dn7 CYCLIC NUCLEOTIDE
BINDING REGULATORY
PROTEIN

(Cytophaga
hutchinsonii) 		PF00027
(cNMP_binding) 		3 PHE A  12
LYS A 131
SER A 132
 None
 0.79A 3tyeB-3dn7A:
undetectable		 3tyeB-3dn7A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eg4 2,3,4,5-TETRAHYDROPY
RIDINE-2,6-DICARBOXY
LATE
N-SUCCINYLTRANSFERAS
E

(Brucella suis) 		PF00132
(Hexapep)
PF14602
(Hexapep_2)
PF14805
(THDPS_N_2) 		3 PHE A 110
LYS A  96
SER A  95
 None
 1.09A 3tyeB-3eg4A:
undetectable		 3tyeB-3eg4A:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fcy XYLAN ESTERASE 1

(Thermoanaerobacterium
saccharolyticum) 		PF05448
(AXE1) 		3 PHE A 314
LYS A 290
SER A 289
 None
 1.26A 3tyeB-3fcyA:
undetectable		 3tyeB-3fcyA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7n NUCLEOPORIN NUP120

(Saccharomyces
cerevisiae) 		PF11715
(Nup160) 		3 PHE A 476
LYS A 356
SER A 361
 None
 1.00A 3tyeB-3h7nA:
undetectable		 3tyeB-3h7nA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hbc CHOLOYLGLYCINE
HYDROLASE

(Bacteroides
thetaiotaomicron) 		PF02275
(CBAH) 		3 PHE A 105
LYS A 163
SER A 109
 None
 1.36A 3tyeB-3hbcA:
undetectable		 3tyeB-3hbcA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hkz DNA-DIRECTED RNA
POLYMERASE SUBUNIT
A'
DNA-DIRECTED RNA
POLYMERASE SUBUNIT B

(Sulfolobus
solfataricus) 		PF00562
(RNA_pol_Rpb2_6)
PF00623
(RNA_pol_Rpb1_2)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		3 PHE A 638
LYS B 980
SER B 981
 None
 1.38A 3tyeB-3hkzA:
undetectable		 3tyeB-3hkzA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR CWF11

(Schizosaccharomyces
pombe) 		PF13087
(AAA_12)
PF16399
(Aquarius_N) 		3 PHE X 570
LYS X 574
SER X 576
 None
 1.35A 3tyeB-3jb9X:
undetectable		 3tyeB-3jb9X:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k2q PYROPHOSPHATE-DEPEND
ENT
PHOSPHOFRUCTOKINASE

(Marinobacter
hydrocarbonoclasticus) 		PF00365
(PFK) 		3 PHE A 392
LYS A 161
SER A 158
 None
 1.33A 3tyeB-3k2qA:
undetectable		 3tyeB-3k2qA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kfu ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Thermus
thermophilus) 		PF02637
(GatB_Yqey)
PF02934
(GatB_N) 		3 PHE F 371
LYS F 382
SER F 383
 None
G  L  18 ( 3.5A)
None
 1.38A 3tyeB-3kfuF:
undetectable		 3tyeB-3kfuF:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3myd FLAGELLAR
BIOSYNTHESIS PROTEIN
FLHA

(Helicobacter
pylori) 		PF00771
(FHIPEP) 		3 PHE A 723
LYS A 625
SER A 626
 None
 1.16A 3tyeB-3mydA:
undetectable		 3tyeB-3mydA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1

(Bacillus
halodurans) 		PF00171
(Aldedh) 		3 PHE A 487
LYS A 495
SER A 494
 None
 1.06A 3tyeB-3qanA:
undetectable		 3tyeB-3qanA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE

(Paraburkholderia
xenovorans) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 PHE A  67
LYS A 301
SER A 299
 None
 1.11A 3tyeB-3sn0A:
10.2		 3tyeB-3sn0A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t7f UBIQUITIN-LIKE
MODIFIER-ACTIVATING
ENZYME ATG7

(Saccharomyces
cerevisiae) 		PF16420
(ATG7_N) 		3 PHE A 128
LYS A  29
SER A  26
 None
 1.20A 3tyeB-3t7fA:
undetectable		 3tyeB-3t7fA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tk8 2,3,4,5-TETRAHYDROPY
RIDINE-2,6-DICARBOXY
LATE
N-SUCCINYLTRANSFERAS
E

(Burkholderia
pseudomallei) 		PF00132
(Hexapep)
PF14602
(Hexapep_2)
PF14805
(THDPS_N_2) 		3 PHE A 142
LYS A 128
SER A 127
 None
 0.96A 3tyeB-3tk8A:
undetectable		 3tyeB-3tk8A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tpa HEME-BINDING PROTEIN
A

(Glaesserella
parasuis) 		PF00496
(SBP_bac_5) 		3 PHE A 120
LYS A  20
SER A  22
 None
 1.33A 3tyeB-3tpaA:
undetectable		 3tyeB-3tpaA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A

(Bacillus
subtilis) 		PF00580
(UvrD-helicase)
PF12705
(PDDEXK_1)
PF13361
(UvrD_C) 		3 PHE A 179
LYS A 820
SER A 821
 None
 1.11A 3tyeB-3u44A:
undetectable		 3tyeB-3u44A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v62 UBIQUITIN-LIKE
PROTEIN SMT3

(Saccharomyces
cerevisiae) 		PF11976
(Rad60-SLD) 		3 PHE A  37
LYS A  28
SER A  33
 None
MLY  A  27 ( 3.3A)
None
 1.38A 3tyeB-3v62A:
undetectable		 3tyeB-3v62A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vh1 UBIQUITIN-LIKE
MODIFIER-ACTIVATING
ENZYME ATG7

(Saccharomyces
cerevisiae) 		PF00899
(ThiF)
PF16420
(ATG7_N) 		3 PHE A 128
LYS A  29
SER A  26
 None
 1.12A 3tyeB-3vh1A:
undetectable		 3tyeB-3vh1A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vx6 E1

(Kluyveromyces
marxianus) 		PF16420
(ATG7_N) 		3 PHE A 124
LYS A  27
SER A  24
 None
 1.25A 3tyeB-3vx6A:
undetectable		 3tyeB-3vx6A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4acq ALPHA-2-MACROGLOBULI
N

(Homo sapiens) 		PF00207
(A2M)
PF01835
(A2M_N)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl) 		3 PHE A 224
LYS A 135
SER A 136
 None
 1.22A 3tyeB-4acqA:
undetectable		 3tyeB-4acqA:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d7x MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 15

([Candida]
glabrata) 		PF16987
(KIX_2) 		3 PHE A  47
LYS A  54
SER A  55
 None
 1.35A 3tyeB-4d7xA:
undetectable		 3tyeB-4d7xA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e9x MULTICOPPER OXIDASE

(uncultured
bacterium) 		PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 PHE A1313
LYS A1173
SER A1169
 None
 1.13A 3tyeB-4e9xA:
undetectable		 3tyeB-4e9xA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ejs ELONGATOR COMPLEX
PROTEIN 6

(Saccharomyces
cerevisiae) 		no annotation 3 PHE C 207
LYS C 214
SER C 215
 None
 1.02A 3tyeB-4ejsC:
undetectable		 3tyeB-4ejsC:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ekd GUANINE
NUCLEOTIDE-BINDING
PROTEIN G(Q) SUBUNIT
ALPHA

(Mus musculus) 		PF00503
(G-alpha) 		3 PHE A 292
LYS A 252
SER A 251
 None
 1.32A 3tyeB-4ekdA:
2.3		 3tyeB-4ekdA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f9d POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE

(Escherichia
coli) 		PF01522
(Polysacc_deac_1)
PF14883
(GHL13) 		3 PHE A 503
LYS A 510
SER A 511
 None
 1.22A 3tyeB-4f9dA:
6.8		 3tyeB-4f9dA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fb5 PROBABLE
OXIDOREDUCTASE
PROTEIN

(Rhizobium etli) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		3 PHE A 164
LYS A 175
SER A 176
 None
 0.80A 3tyeB-4fb5A:
undetectable		 3tyeB-4fb5A:
25.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fio METHENYLTETRAHYDROME
THANOPTERIN
CYCLOHYDROLASE

(Methanobrevibacter
ruminantium) 		PF02289
(MCH) 		3 PHE A 167
LYS A  28
SER A  27
 None
 1.27A 3tyeB-4fioA:
undetectable		 3tyeB-4fioA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i6m ACTIN-RELATED
PROTEIN 7

(Saccharomyces
cerevisiae) 		PF00022
(Actin) 		3 PHE A 323
LYS A 183
SER A 182
 None
 1.02A 3tyeB-4i6mA:
undetectable		 3tyeB-4i6mA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jw1 EFFECTOR PROTEIN B

(Legionella
pneumophila) 		no annotation 3 PHE A 172
LYS A 168
SER A 169
 None
 1.00A 3tyeB-4jw1A:
undetectable		 3tyeB-4jw1A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lnf GLUTAMINE SYNTHETASE

(Bacillus
subtilis) 		PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N) 		3 PHE A 428
LYS A 297
SER A 295
 None
 1.30A 3tyeB-4lnfA:
undetectable		 3tyeB-4lnfA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lq1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB

(Escherichia
coli) 		PF00128
(Alpha-amylase)
PF02806
(Alpha-amylase_C)
PF02922
(CBM_48) 		3 PHE A 346
LYS A 202
SER A 203
 None
 1.33A 3tyeB-4lq1A:
5.0		 3tyeB-4lq1A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mlo TCP PILUS VIRULENCE
REGULATORY PROTEIN

(Vibrio cholerae) 		PF00165
(HTH_AraC) 		3 PHE A 147
LYS A 154
SER A 153
 None
 1.07A 3tyeB-4mloA:
undetectable		 3tyeB-4mloA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o3m BLOOM SYNDROME
PROTEIN

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF00570
(HRDC)
PF09382
(RQC)
PF16124
(RecQ_Zn_bind) 		3 PHE A1238
LYS A 726
SER A 729
 None
 0.74A 3tyeB-4o3mA:
undetectable		 3tyeB-4o3mA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ofp PROTEIN SYG-2

(Caenorhabditis
elegans) 		PF00047
(ig)
PF13927
(Ig_3) 		3 PHE A 380
LYS A 353
SER A 354
 None
 1.02A 3tyeB-4ofpA:
undetectable		 3tyeB-4ofpA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p7l POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE

(Escherichia
coli) 		PF14883
(GHL13) 		3 PHE A 503
LYS A 510
SER A 511
 None
 1.30A 3tyeB-4p7lA:
8.1		 3tyeB-4p7lA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pg6 HOMOSERINE
DEHYDROGENASE

(Staphylococcus
aureus) 		PF00742
(Homoserine_dh)
PF03447
(NAD_binding_3) 		3 PHE A 381
LYS A 354
SER A 355
 None
 1.24A 3tyeB-4pg6A:
undetectable		 3tyeB-4pg6A:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qci ANTI-PDGF-BB
ANTIBODY - LIGHT
CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 PHE A 169
LYS A 102
SER A   9
 None
 0.91A 3tyeB-4qciA:
undetectable		 3tyeB-4qciA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qrm FLAGELLAR MOTOR
SWITCH PROTEIN FLIM

(Thermotoga
maritima) 		PF02154
(FliM) 		3 PHE A  55
LYS A 226
SER A 228
 None
 1.15A 3tyeB-4qrmA:
undetectable		 3tyeB-4qrmA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s3h MDB1

(Schizosaccharomyces
pombe) 		no annotation 3 PHE A  18
LYS A  69
SER A  64
 None
 1.27A 3tyeB-4s3hA:
undetectable		 3tyeB-4s3hA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xae FERULOYL COA
ORTHO-HYDROXYLASE 1

(Arabidopsis
thaliana) 		PF03171
(2OG-FeII_Oxy)
PF14226
(DIOX_N) 		3 PHE A 156
LYS A 182
SER A 181
 None
 0.83A 3tyeB-4xaeA:
undetectable		 3tyeB-4xaeA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xmm NUCLEOPORIN NUP120

(Saccharomyces
cerevisiae) 		no annotation 3 PHE E 476
LYS E 356
SER E 361
 None
 1.00A 3tyeB-4xmmE:
undetectable		 3tyeB-4xmmE:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN

(Thauera
aromatica) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		3 PHE A 385
LYS A 377
SER A 378
 None
 0.90A 3tyeB-5bwdA:
2.5		 3tyeB-5bwdA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5diz PROTEINACEOUS RNASE
P 2

(Arabidopsis
thaliana) 		PF16953
(PRORP)
PF17177
(PPR_long) 		3 PHE A  35
LYS A  42
SER A  41
 None
 1.01A 3tyeB-5dizA:
undetectable		 3tyeB-5dizA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5diz PROTEINACEOUS RNASE
P 2

(Arabidopsis
thaliana) 		PF16953
(PRORP)
PF17177
(PPR_long) 		3 PHE A  35
LYS A  42
SER A  43
 None
 1.37A 3tyeB-5dizA:
undetectable		 3tyeB-5dizA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fav CHOLINE
TRIMETHYLAMINE-LYASE

(Desulfovibrio
alaskensis) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		3 PHE A 175
LYS A 179
SER A 180
 None
 1.31A 3tyeB-5favA:
undetectable		 3tyeB-5favA:
18.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5jq9 DIHYDROPTEROATE
SYNTHASE

(Yersinia pestis) 		PF00809
(Pterin_bind) 		3 PHE A 190
LYS A 221
SER A 222
 6MB  A 301 (-3.9A)
6MB  A 301 (-2.7A)
6MB  A 301 (-2.6A)
 0.44A 3tyeB-5jq9A:
37.3		 3tyeB-5jq9A:
39.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k04 UNCHARACTERIZED
PROTEIN

(Candida
albicans) 		PF09797
(NatB_MDM20) 		3 PHE A 121
LYS A 495
SER A 494
 None
 1.11A 3tyeB-5k04A:
undetectable		 3tyeB-5k04A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kdx METALLOPEPTIDASE

(Pseudomonas
aeruginosa) 		PF13402
(Peptidase_M60) 		3 PHE A 452
LYS A 504
SER A 505
 None
EDO  A1011 (-4.0A)
EDO  A1011 ( 3.6A)
 1.00A 3tyeB-5kdxA:
undetectable		 3tyeB-5kdxA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kf7 BIFUNCTIONAL PROTEIN
PUTA

(Sinorhizobium
meliloti) 		PF00171
(Aldedh)
PF01619
(Pro_dh)
PF14850
(Pro_dh-DNA_bdg) 		3 PHE A 708
LYS A 663
SER A 664
 PG4  A2005 (-3.7A)
None
None
 1.39A 3tyeB-5kf7A:
7.7		 3tyeB-5kf7A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mz9 -

(-) 		no annotation 3 PHE A 378
LYS A 567
SER A 558
 None
 1.27A 3tyeB-5mz9A:
undetectable		 3tyeB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ojs TRANSCRIPTION-ASSOCI
ATED PROTEIN 1

(Saccharomyces
cerevisiae) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT) 		3 PHE T 294
LYS T 214
SER T 216
 None
 1.31A 3tyeB-5ojsT:
undetectable		 3tyeB-5ojsT:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t5w INTERFERON LAMBDA
RECEPTOR 1

(Homo sapiens) 		PF01108
(Tissue_fac) 		3 PHE B  36
LYS B  88
SER B  89
 None
 0.75A 3tyeB-5t5wB:
undetectable		 3tyeB-5t5wB:
17.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5umg DIHYDROPTEROATE
SYNTHASE

(Klebsiella
pneumoniae) 		PF00809
(Pterin_bind) 		3 PHE A 190
LYS A 221
SER A 222
 None
 0.65A 3tyeB-5umgA:
35.9		 3tyeB-5umgA:
40.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5usw DIHYDROPTEROATE
SYNTHASE

(Aliivibrio
fischeri) 		PF00809
(Pterin_bind) 		3 PHE A 190
LYS A 221
SER A 222
 GOL  A 303 (-4.7A)
GOL  A 303 (-2.8A)
None
 0.57A 3tyeB-5uswA:
34.5		 3tyeB-5uswA:
37.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vgb CRISPR-ASSOCIATED
ENDONUCLEASE CAS9

(Neisseria
meningitidis) 		PF13395
(HNH_4) 		3 PHE A  87
LYS A 135
SER A 134
 None
 0.69A 3tyeB-5vgbA:
undetectable		 3tyeB-5vgbA:
18.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5vis DIHYDROPTEROATE
SYNTHASE

(soil metagenome) 		PF00809
(Pterin_bind) 		3 PHE A 183
LYS A 215
SER A 216
 None
 0.71A 3tyeB-5visA:
33.3		 3tyeB-5visA:
34.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xtb NADH-UBIQUINONE
OXIDOREDUCTASE 75
KDA SUBUNIT,
MITOCHONDRIAL

(Homo sapiens) 		PF00384
(Molybdopterin)
PF09326
(NADH_dhqG_C)
PF10588
(NADH-G_4Fe-4S_3)
PF13510
(Fer2_4) 		3 PHE M 238
LYS M 170
SER M 233
 None
 1.25A 3tyeB-5xtbM:
undetectable		 3tyeB-5xtbM:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xxu RIBOSOMAL PROTEIN
US10
RIBOSOMAL PROTEIN
US9

(Toxoplasma
gondii) 		PF00338
(Ribosomal_S10)
PF00380
(Ribosomal_S9) 		3 PHE Q 134
LYS U 181
SER U 182
 None
C  21416 ( 3.5A)
C  21275 ( 4.4A)
 1.34A 3tyeB-5xxuQ:
undetectable		 3tyeB-5xxuQ:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyj ACETYL-COA
ACETYLTRANSFERASE

(Saccharomyces
cerevisiae) 		no annotation 3 PHE B 181
LYS B 188
SER B 189
 None
 1.20A 3tyeB-5xyjB:
undetectable		 3tyeB-5xyjB:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b8d ELONGATION FACTOR G

(Haemophilus
influenzae) 		no annotation 3 PHE A  79
LYS A 249
SER A 250
 None
 1.34A 3tyeB-6b8dA:
undetectable		 3tyeB-6b8dA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cwr -

(-) 		no annotation 3 PHE A 185
LYS A 192
SER A 191
 None
 1.12A 3tyeB-6cwrA:
undetectable		 3tyeB-6cwrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d6v TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila) 		no annotation 3 PHE A1060
LYS A1067
SER A1068
 C  B  62 ( 3.7A)
None
None
 1.02A 3tyeB-6d6vA:
undetectable		 3tyeB-6d6vA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6erc PEROXINECTIN A

(Dictyostelium
discoideum) 		no annotation 3 PHE A 331
LYS A 348
SER A 350
 None
 1.25A 3tyeB-6ercA:
undetectable		 3tyeB-6ercA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ewx PEAK1-RELATED
KINASE-ACTIVATING
PSEUDOKINASE 1

(Rattus
norvegicus) 		no annotation 3 PHE A 957
LYS A 988
SER A 987
 None
 1.34A 3tyeB-6ewxA:
undetectable		 3tyeB-6ewxA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fay ODZ3 PROTEIN

(Mus musculus) 		no annotation 3 PHE A1964
LYS A2226
SER A2225
 None
 1.27A 3tyeB-6fayA:
undetectable		 3tyeB-6fayA:
14.53