SIMILAR PATTERNS OF AMINO ACIDS FOR 3TWP_D_SALD404_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a4e | CATALASE A (Saccharomycescerevisiae) |
PF00199(Catalase)PF06628(Catalase-rel) | 4 | ASN A 137PRO A 375TYR A 376ALA A 377 | None | 1.23A | 3twpD-1a4eA:0.0 | 3twpD-1a4eA:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bt4 | PHOSPHOSERINEAMINOTRANSFERASE (Bacilluscirculans) |
PF00266(Aminotran_5) | 4 | ASN A 7ALA A 14TYR A 339ALA A 10 | None | 1.36A | 3twpD-1bt4A:0.8 | 3twpD-1bt4A:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bvy | PROTEIN (CYTOCHROMEP450 BM-3) (Bacillusmegaterium) |
PF00258(Flavodoxin_1) | 4 | ASN F 543ALA F 544PRO F 541ALA F 493 | NoneNoneNoneFMN F1002 (-3.4A) | 1.09A | 3twpD-1bvyF:1.5 | 3twpD-1bvyF:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cg2 | CARBOXYPEPTIDASE G2 (Pseudomonas sp.RS-16) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 4 | ALA A 36PRO A 398TYR A 402ALA A 347 | None | 1.07A | 3twpD-1cg2A:0.0 | 3twpD-1cg2A:23.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cg2 | CARBOXYPEPTIDASE G2 (Pseudomonas sp.RS-16) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 4 | ASN A 292ALA A 326PRO A 325ALA A 367 | None | 1.10A | 3twpD-1cg2A:0.0 | 3twpD-1cg2A:23.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1crz | TOLB PROTEIN (Escherichiacoli) |
PF04052(TolB_N)PF07676(PD40) | 4 | ASN A 364ALA A 362PRO A 363TYR A 166 | None | 1.17A | 3twpD-1crzA:2.9 | 3twpD-1crzA:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dwa | MYROSINASE MA1 (Sinapis alba) |
PF00232(Glyco_hydro_1) | 4 | ALA M 227PRO M 192TYR M 224ALA M 349 | None | 1.28A | 3twpD-1dwaM:0.0 | 3twpD-1dwaM:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fbw | ENDO-1,4-BETA-GLUCANASE F ([Clostridium]cellulolyticum) |
PF02011(Glyco_hydro_48) | 4 | ASN A 227ALA A 228PRO A 229ALA A 233 | NoneGLC A3098 ( 4.0A)NoneNone | 1.24A | 3twpD-1fbwA:1.6 | 3twpD-1fbwA:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ggp | PROTEIN (LECTIN 1 ACHAIN) (Trichosantheskirilowii) |
PF00161(RIP) | 4 | ASN A 72ALA A 74TYR A 51ALA A 50 | None | 1.26A | 3twpD-1ggpA:undetectable | 3twpD-1ggpA:24.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j0n | XANTHAN LYASE (Bacillus sp.GL1) |
PF02278(Lyase_8)PF02884(Lyase_8_C)PF08124(Lyase_8_N) | 4 | ALA A 386PRO A 387TYR A 298ALA A 407 | None | 1.10A | 3twpD-1j0nA:1.7 | 3twpD-1j0nA:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1js8 | HEMOCYANIN (Enteroctopusdofleini) |
PF00264(Tyrosinase)PF14830(Haemocyan_bet_s) | 4 | ALA A2618PRO A2696TYR A2694ALA A2540 | None | 1.34A | 3twpD-1js8A:undetectable | 3twpD-1js8A:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k0r | NUSA (Mycobacteriumtuberculosis) |
PF08529(NusA_N)PF13184(KH_5) | 4 | ASN A 309ALA A 275PRO A 274ALA A 271 | None | 1.34A | 3twpD-1k0rA:undetectable | 3twpD-1k0rA:23.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l5x | SURVIVAL PROTEIN E (Pyrobaculumaerophilum) |
PF01975(SurE) | 4 | ASN A 7ALA A 33PRO A 34ALA A 111 | None | 1.27A | 3twpD-1l5xA:2.6 | 3twpD-1l5xA:25.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lss | TRK SYSTEM POTASSIUMUPTAKE PROTEIN TRKAHOMOLOG (Methanocaldococcusjannaschii) |
PF02254(TrkA_N) | 4 | ASN A 79ALA A 96TYR A 69ALA A 6 | None | 1.12A | 3twpD-1lssA:4.0 | 3twpD-1lssA:17.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nl3 | PREPROTEINTRANSLOCASE SECA 1SUBUNIT (Mycobacteriumtuberculosis) |
PF01043(SecA_PP_bind)PF07516(SecA_SW)PF07517(SecA_DEAD) | 4 | ALA A 115PRO A 114TYR A 116ALA A 70 | None | 1.23A | 3twpD-1nl3A:1.9 | 3twpD-1nl3A:18.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pdz | ENOLASE (Homarusgammarus) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | ASN A 160ALA A 213PRO A 214ALA A 222 | None | 1.42A | 3twpD-1pdzA:undetectable | 3twpD-1pdzA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pw4 | GLYCEROL-3-PHOSPHATETRANSPORTER (Escherichiacoli) |
PF07690(MFS_1) | 4 | ALA A 194PRO A 193TYR A 191ALA A 189 | None | 1.36A | 3twpD-1pw4A:undetectable | 3twpD-1pw4A:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1szq | 2-METHYLCITRATEDEHYDRATASE (Escherichiacoli) |
PF03972(MmgE_PrpD) | 4 | ASN A 405ALA A 404TYR A 395ALA A 327 | None | 1.32A | 3twpD-1szqA:undetectable | 3twpD-1szqA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u08 | HYPOTHETICALAMINOTRANSFERASEYBDL (Escherichiacoli) |
PF00155(Aminotran_1_2) | 4 | ASN A 270ALA A 273PRO A 272ALA A 64 | None | 1.06A | 3twpD-1u08A:undetectable | 3twpD-1u08A:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wmr | ISOPULLULANASE (Aspergillusniger) |
PF03718(Glyco_hydro_49)PF17433(Glyco_hydro_49N) | 4 | ALA A 319PRO A 320TYR A 275ALA A 252 | None | 1.21A | 3twpD-1wmrA:undetectable | 3twpD-1wmrA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wve | 4-CRESOLDEHYDROGENASE[HYDROXYLATING]FLAVOPROTEIN SUBUNIT (Pseudomonasputida) |
PF01565(FAD_binding_4)PF02913(FAD-oxidase_C) | 4 | ALA A 99PRO A 100TYR A 44ALA A 61 | None | 1.42A | 3twpD-1wveA:undetectable | 3twpD-1wveA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y79 | PEPTIDYL-DIPEPTIDASEDCP (Escherichiacoli) |
PF01432(Peptidase_M3) | 4 | ASN 1 4ALA 1 30PRO 1 29TYR 1 27 | None | 0.80A | 3twpD-1y791:undetectable | 3twpD-1y791:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yr1 | CELL-DIVISIONINITIATION PROTEIN (Geobacillusstearothermophilus) |
no annotation | 4 | ASN A 202ALA A 181TYR A 221ALA A 223 | None | 1.38A | 3twpD-1yr1A:undetectable | 3twpD-1yr1A:15.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zy8 | DIHYDROLIPOYLDEHYDROGENASE,MITOCHONDRIAL (Homo sapiens) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | ASN A 430ALA A 433PRO A 355ALA A 365 | None | 1.23A | 3twpD-1zy8A:undetectable | 3twpD-1zy8A:24.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bi3 | PHOSPHOSERINEAMINOTRANSFERASE (Bacillusalcalophilus) |
PF00266(Aminotran_5) | 4 | ASN A 6ALA A 13TYR A 338ALA A 9 | None | 1.37A | 3twpD-2bi3A:undetectable | 3twpD-2bi3A:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bws | XAA-PROAMINOPEPTIDASE P (Escherichiacoli) |
PF00557(Peptidase_M24)PF05195(AMP_N) | 4 | ASN A 46ALA A 30TYR A 136ALA A 137 | None | 1.36A | 3twpD-2bwsA:undetectable | 3twpD-2bwsA:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d3v | LEUKOCYTEIMMUNOGLOBULIN-LIKERECEPTOR SUBFAMILY AMEMBER 5 ISOFORM 1 (Homo sapiens) |
PF13895(Ig_2) | 4 | ALA A 81PRO A 80TYR A 77ALA A 32 | None | 1.25A | 3twpD-2d3vA:undetectable | 3twpD-2d3vA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e6e | 5'-NUCLEOTIDASE SURE (Thermusthermophilus) |
PF01975(SurE) | 4 | ASN A 7ALA A 33PRO A 34ALA A 113 | None | 1.15A | 3twpD-2e6eA:undetectable | 3twpD-2e6eA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fa0 | HMG-COA SYNTHASE (Brassica juncea) |
PF01154(HMG_CoA_synt_N)PF08540(HMG_CoA_synt_C) | 4 | ASN A 115ALA A 116TYR A 357ALA A 363 | NoneHMG A 500 (-2.5A)HMG A 500 (-4.4A)None | 1.33A | 3twpD-2fa0A:undetectable | 3twpD-2fa0A:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iiz | MELANIN BIOSYNTHESISPROTEIN TYRA,PUTATIVE (Shewanellaoneidensis) |
PF04261(Dyp_perox) | 4 | ASN A 68ALA A 67PRO A 84ALA A 97 | None | 0.84A | 3twpD-2iizA:undetectable | 3twpD-2iizA:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kbf | ATP-DEPENDENT RNAHELICASE DBP5 (Saccharomycescerevisiae) |
PF00271(Helicase_C) | 4 | ASN A 388ALA A 338PRO A 408ALA A 411 | None | 0.91A | 3twpD-2kbfA:undetectable | 3twpD-2kbfA:18.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p8u | HYDROXYMETHYLGLUTARYL-COA SYNTHASE,CYTOPLASMIC (Homo sapiens) |
PF01154(HMG_CoA_synt_N)PF08540(HMG_CoA_synt_C) | 4 | ASN A 127ALA A 128TYR A 375ALA A 381 | NoneSCY A 129 ( 2.9A)NoneNone | 1.29A | 3twpD-2p8uA:undetectable | 3twpD-2p8uA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rg4 | UNCHARACTERIZEDPROTEIN (Oceanicolagranulosus) |
PF13759(2OG-FeII_Oxy_5) | 4 | ASN A 192ALA A 194PRO A 135ALA A 140 | None | 1.36A | 3twpD-2rg4A:undetectable | 3twpD-2rg4A:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vyi | SGTA PROTEIN (Homo sapiens) |
PF00515(TPR_1)PF13181(TPR_8) | 4 | ALA A 157PRO A 156TYR A 158ALA A 125 | None | 1.09A | 3twpD-2vyiA:undetectable | 3twpD-2vyiA:18.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wya | HYDROXYMETHYLGLUTARYL-COA SYNTHASE,MITOCHONDRIAL (Homo sapiens) |
PF01154(HMG_CoA_synt_N)PF08540(HMG_CoA_synt_C) | 4 | ASN A 164ALA A 165TYR A 412ALA A 418 | NoneHMG A1509 (-3.1A)HMG A1509 ( 4.8A)None | 1.30A | 3twpD-2wyaA:undetectable | 3twpD-2wyaA:19.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3anv | D-SERINE DEHYDRATASE (Gallus gallus) |
PF01168(Ala_racemase_N)PF14031(D-ser_dehydrat) | 4 | ASN A 162ALA A 161PRO A 213ALA A 210 | None | 1.28A | 3twpD-3anvA:undetectable | 3twpD-3anvA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gxk | GOOSE-TYPE LYSOZYME1 (Gadus morhua) |
PF01464(SLT) | 4 | ASN A 53ALA A 56PRO A 63ALA A 67 | None | 1.28A | 3twpD-3gxkA:undetectable | 3twpD-3gxkA:17.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jzd | IRON-CONTAININGALCOHOLDEHYDROGENASE (Cupriaviduspinatubonensis) |
PF00465(Fe-ADH) | 4 | ASN A 271PRO A 335TYR A 332ALA A 239 | None | 1.23A | 3twpD-3jzdA:undetectable | 3twpD-3jzdA:26.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k5p | D-3-PHOSPHOGLYCERATEDEHYDROGENASE (Brucellaabortus) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 4 | ASN A 327ALA A 325TYR A 316ALA A 79 | None | 1.01A | 3twpD-3k5pA:undetectable | 3twpD-3k5pA:23.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m6a | ATP-DEPENDENTPROTEASE LA 1 (Bacillussubtilis) |
PF00004(AAA)PF05362(Lon_C) | 4 | ASN A 738ALA A 734PRO A 735ALA A 677 | None | 1.33A | 3twpD-3m6aA:undetectable | 3twpD-3m6aA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mq2 | 16S RRNAMETHYLTRANSFERASE (Streptoalloteichustenebrarius) |
PF02390(Methyltransf_4) | 4 | ASN A 79ALA A 43TYR A 40ALA A 68 | None | 1.22A | 3twpD-3mq2A:3.8 | 3twpD-3mq2A:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ouo | NUCLEOPROTEIN (Rift Valleyfeverphlebovirus) |
PF05733(Tenui_N) | 4 | ALA A 139PRO A 138TYR A 140ALA A 237 | None | 1.29A | 3twpD-3ouoA:undetectable | 3twpD-3ouoA:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3phf | ENVELOPEGLYCOPROTEIN H (Humangammaherpesvirus4) |
no annotation | 4 | ALA A 531PRO A 530TYR A 532ALA A 526 | None | 1.40A | 3twpD-3phfA:undetectable | 3twpD-3phfA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3phf | ENVELOPEGLYCOPROTEIN H (Humangammaherpesvirus4) |
no annotation | 4 | ASN A 585ALA A 531PRO A 530ALA A 444 | None | 1.03A | 3twpD-3phfA:undetectable | 3twpD-3phfA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rmg | OCTAPRENYL-DIPHOSPHATE SYNTHASE (Bacteroidesthetaiotaomicron) |
PF00348(polyprenyl_synt) | 4 | ALA A 285PRO A 239TYR A 242ALA A 243 | None | 1.25A | 3twpD-3rmgA:undetectable | 3twpD-3rmgA:24.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t4w | MANDELATERACEMASE/MUCONATELACTONIZING ENZYMEFAMILY PROTEIN (Sulfitobactersp. NAS-14.1) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ASN A 223ALA A 226PRO A 253TYR A 233 | None | 1.29A | 3twpD-3t4wA:undetectable | 3twpD-3t4wA:24.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t63 | PROTOCATECHUATE3,4-DIOXYGENASE BETACHAIN (Pseudomonasputida) |
PF00775(Dioxygenase_C)PF12391(PCDO_beta_N) | 4 | ASN M 403ALA M 402TYR M 415ALA M 417 | None | 1.32A | 3twpD-3t63M:undetectable | 3twpD-3t63M:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ttf | TRANSCRIPTIONALREGULATORY PROTEIN (Escherichiacoli) |
PF01300(Sua5_yciO_yrdC)PF07503(zf-HYPF) | 4 | ASN A 549ALA A 542PRO A 537ALA A 591 | None | 1.37A | 3twpD-3ttfA:undetectable | 3twpD-3ttfA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ty2 | 5'-NUCLEOTIDASE SURE (Coxiellaburnetii) |
PF01975(SurE) | 4 | ASN A 18ALA A 44PRO A 45ALA A 119 | None | 1.18A | 3twpD-3ty2A:2.9 | 3twpD-3ty2A:24.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zhb | R-IMINE REDUCTASE (Streptomyceskanamyceticus) |
PF03446(NAD_binding_2) | 4 | ALA A 158PRO A 155TYR A 131ALA A 121 | None | 1.37A | 3twpD-3zhbA:undetectable | 3twpD-3zhbA:27.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a05 | CELLOBIOHYDROLASEFAMILY 6 (Chaetomiumthermophilum) |
PF01341(Glyco_hydro_6) | 4 | ASN A 185ALA A 189PRO A 192ALA A 194 | None | 1.09A | 3twpD-4a05A:undetectable | 3twpD-4a05A:24.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ayg | GLUCANSUCRASE (Lactobacillusreuteri) |
PF01473(CW_binding_1)PF02324(Glyco_hydro_70) | 4 | ALA A1071PRO A1070TYR A1072ALA A 967 | GOL A2771 (-3.2A)GOL A2771 (-3.7A)NoneGOL A2792 ( 4.1A) | 1.41A | 3twpD-4aygA:undetectable | 3twpD-4aygA:17.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e6w | CLBP PEPTIDASE (Escherichiacoli) |
PF00144(Beta-lactamase) | 4 | ALA A 260PRO A 259TYR A 262ALA A 254 | None | 1.25A | 3twpD-4e6wA:undetectable | 3twpD-4e6wA:23.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fus | RTX TOXINS ANDRELATED CA2+-BINDINGPROTEIN (Hahellachejuensis) |
PF02011(Glyco_hydro_48) | 4 | ASN A 252ALA A 253PRO A 254ALA A 258 | NoneGOL A 805 (-3.7A)NoneNone | 1.29A | 3twpD-4fusA:undetectable | 3twpD-4fusA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hjh | PHOSPHOMANNOMUTASE (Brucellamelitensis) |
PF00408(PGM_PMM_IV)PF02878(PGM_PMM_I)PF02879(PGM_PMM_II)PF02880(PGM_PMM_III) | 4 | ALA A 25PRO A 24TYR A 26ALA A 143 | NoneNoneNoneIOD A 517 ( 3.8A) | 1.41A | 3twpD-4hjhA:undetectable | 3twpD-4hjhA:26.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ir8 | SEDOHEPTULOSE-1,7BISPHOSPHATASE,PUTATIVE (Toxoplasmagondii) |
PF00316(FBPase) | 4 | ALA A 221PRO A 220TYR A 222ALA A 215 | None | 1.42A | 3twpD-4ir8A:undetectable | 3twpD-4ir8A:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jjj | CELLULOSE1,4-BETA-CELLOBIOSIDASE (Thermobifidafusca) |
PF02011(Glyco_hydro_48) | 4 | ASN A 221ALA A 222PRO A 223ALA A 227 | NoneCE6 A 703 ( 4.1A)NoneNone | 1.30A | 3twpD-4jjjA:undetectable | 3twpD-4jjjA:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4juu | EPIMERASE (Xanthomonascampestris) |
PF05544(Pro_racemase) | 4 | ALA A 283PRO A 284TYR A 275ALA A 250 | None | 1.36A | 3twpD-4juuA:undetectable | 3twpD-4juuA:23.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lvo | SUBTILISIN-LIKESERINE PROTEASE (Plasmodiumfalciparum) |
PF00082(Peptidase_S8) | 4 | ASN A 488ALA A 609PRO A 610ALA A 614 | None | 1.28A | 3twpD-4lvoA:3.0 | 3twpD-4lvoA:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mjt | MONALYSIN (Pseudomonasentomophila) |
no annotation | 4 | ASN A 193ALA A 196TYR A 213ALA A 186 | None | 1.35A | 3twpD-4mjtA:undetectable | 3twpD-4mjtA:17.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mkq | MONALYSIN (Pseudomonasentomophila) |
no annotation | 4 | ASN A 193ALA A 196TYR A 213ALA A 186 | None | 1.34A | 3twpD-4mkqA:undetectable | 3twpD-4mkqA:17.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pv4 | PROLINEAMINOPEPTIDASE P II (Yersinia pestis) |
PF00557(Peptidase_M24)PF05195(AMP_N) | 4 | ASN A 44ALA A 28TYR A 134ALA A 135 | None | 1.34A | 3twpD-4pv4A:undetectable | 3twpD-4pv4A:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qb7 | UNCHARACTERIZEDPROTEIN (Bacteroidesvulgatus) |
PF13149(Mfa_like_1) | 4 | ASN A 295PRO A 292TYR A 223ALA A 226 | NoneNoneSO4 A 416 (-4.7A)None | 0.93A | 3twpD-4qb7A:undetectable | 3twpD-4qb7A:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rae | HISTIDINOL-PHOSPHATEAMINOTRANSFERASE (Mycobacteriumtuberculosis) |
PF00155(Aminotran_1_2) | 4 | ASN A 175ALA A 172TYR A 204ALA A 311 | None | 1.15A | 3twpD-4raeA:undetectable | 3twpD-4raeA:26.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rqo | L-SERINE DEHYDRATASE (Legionellapneumophila) |
PF03313(SDH_alpha)PF03315(SDH_beta) | 4 | ASN A 28ALA A 75PRO A 76ALA A 66 | None | 1.23A | 3twpD-4rqoA:undetectable | 3twpD-4rqoA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rx1 | PUTATIVE RRNAMETHYLTRANSFERASE (Sorangiumcellulosum) |
no annotation | 4 | ASN A 79ALA A 43TYR A 40ALA A 68 | None | 1.32A | 3twpD-4rx1A:3.4 | 3twpD-4rx1A:23.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wxx | DNA(CYTOSINE-5)-METHYLTRANSFERASE 1 (Homo sapiens) |
PF00145(DNA_methylase)PF01426(BAH)PF02008(zf-CXXC)PF12047(DNMT1-RFD) | 4 | ASN A 383ALA A 439TYR A 486ALA A 484 | None | 1.36A | 3twpD-4wxxA:undetectable | 3twpD-4wxxA:15.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xk1 | PHOSPHOSERINEAMINOTRANSFERASE (Pseudomonasaeruginosa) |
PF00266(Aminotran_5) | 4 | ASN A 7ALA A 14TYR A 338ALA A 10 | NoneNoneLLP A 197 ( 4.0A)None | 1.36A | 3twpD-4xk1A:undetectable | 3twpD-4xk1A:23.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xwl | EXOGLUCANASE S (Clostridiumcellulovorans) |
PF02011(Glyco_hydro_48) | 4 | ASN A 219ALA A 220PRO A 221ALA A 225 | NonePGE A 712 (-3.5A)NoneNone | 1.28A | 3twpD-4xwlA:3.1 | 3twpD-4xwlA:19.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ywe | PUTATIVE ALDEHYDEDEHYDROGENASE (Burkholderiacenocepacia) |
PF00171(Aldedh) | 4 | ASN A 168ALA A 166PRO A 139ALA A 470 | None | 1.40A | 3twpD-4yweA:3.2 | 3twpD-4yweA:24.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zhs | ASPARTATESEMIALDEHYDEDEHYDROGENASE (Trichophytonrubrum) |
no annotation | 4 | ASN D 112ALA D 110PRO D 89ALA D 91 | None | 1.27A | 3twpD-4zhsD:3.2 | 3twpD-4zhsD:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5axh | DEXTRANASE (Thermoanaerobacterpseudethanolicus) |
PF13199(Glyco_hydro_66) | 4 | ASN A 157ALA A 156PRO A 454ALA A 456 | None | 1.18A | 3twpD-5axhA:undetectable | 3twpD-5axhA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bw4 | 16S RRNA(ADENINE(1408)-N(1))-METHYLTRANSFERASE (Catenulisporaacidiphila) |
no annotation | 4 | ASN A 85ALA A 49TYR A 46ALA A 74 | None | 1.26A | 3twpD-5bw4A:3.3 | 3twpD-5bw4A:25.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c3l | NUCLEOPORIN NUP58 (Xenopus laevis) |
PF15967(Nucleoporin_FG2) | 4 | ASN B 373ALA B 375PRO B 376ALA B 359 | None | 0.98A | 3twpD-5c3lB:undetectable | 3twpD-5c3lB:15.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d2e | MLNE (Bacillusvelezensis) |
PF08659(KR) | 4 | ASN A 189ALA A 190TYR A 175ALA A 209 | None | 1.32A | 3twpD-5d2eA:undetectable | 3twpD-5d2eA:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e9a | BETA-GALACTOSIDASE (Rahnella sp. R3) |
PF02449(Glyco_hydro_42)PF08532(Glyco_hydro_42M)PF08533(Glyco_hydro_42C) | 4 | ASN A 597ALA A 551TYR A 569ALA A 579 | None | 0.96A | 3twpD-5e9aA:undetectable | 3twpD-5e9aA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eqw | PUTATIVE MAJOR COATPROTEIN (Acidianustailed spindlevirus) |
no annotation | 4 | ASN A 88ALA A 89PRO A 86TYR A 79 | None | 1.30A | 3twpD-5eqwA:undetectable | 3twpD-5eqwA:17.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f8v | AMINOTRANSFERASE,CLASS V FAMILYPROTEIN (Trichomonasvaginalis) |
PF00266(Aminotran_5) | 4 | ASN A 8ALA A 15TYR A 350ALA A 11 | NoneNoneLLP A 202 ( 4.0A)None | 1.38A | 3twpD-5f8vA:undetectable | 3twpD-5f8vA:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gj8 | ACYL-COADEHYDROGENASE TYPE 2DOMAIN PROTEIN (Alicyclobacillusacidocaldarius) |
PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N)PF08028(Acyl-CoA_dh_2) | 4 | ASN A 338ALA A 337TYR A 253ALA A 368 | None | 1.39A | 3twpD-5gj8A:undetectable | 3twpD-5gj8A:25.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gt2 | PROBABLEDEFERROCHELATASE/PEROXIDASE YFEX (Escherichiacoli) |
PF04261(Dyp_perox) | 4 | ALA A 292PRO A 293TYR A 171ALA A 74 | None | 1.39A | 3twpD-5gt2A:undetectable | 3twpD-5gt2A:23.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i08 | SPIKE GLYCOPROTEIN,ENVELOPEGLYCOPROTEIN CHIMERA (HumancoronavirusHKU1;Humanimmunodeficiencyvirus 1) |
PF01601(Corona_S2)PF09408(Spike_rec_bind)PF16451(Spike_NTD) | 4 | ASN A 722ALA A 689PRO A 688TYR A 746 | None | 1.34A | 3twpD-5i08A:undetectable | 3twpD-5i08A:14.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jjo | UNCHARACTERIZEDPROTEIN (Pseudomonasaeruginosa) |
PF08238(Sel1) | 4 | ASN A 128ALA A 123TYR A 120ALA A 154 | None | 1.01A | 3twpD-5jjoA:undetectable | 3twpD-5jjoA:22.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kss | 5'-NUCLEOTIDASE SURE (Xylellafastidiosa) |
PF01975(SurE) | 4 | ASN A 7ALA A 34PRO A 35ALA A 109 | None | 1.12A | 3twpD-5kssA:3.5 | 3twpD-5kssA:23.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l44 | K-26 DIPEPTIDYLCARBOXYPEPTIDASE (Astrosporangiumhypotensionis) |
PF01432(Peptidase_M3) | 4 | ASN A 11ALA A 37PRO A 36TYR A 34 | None | 0.94A | 3twpD-5l44A:undetectable | 3twpD-5l44A:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lc2 | PROTEIN FAM3C (Homo sapiens) |
PF15711(ILEI) | 4 | ASN A 181PRO A 213TYR A 209ALA A 78 | None | 1.24A | 3twpD-5lc2A:undetectable | 3twpD-5lc2A:18.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lva | NAD(P)H-FMNOXIDOREDUCTASE (Bacillussubtilis) |
PF02525(Flavodoxin_2) | 4 | ASN A 120ALA A 113TYR A 149ALA A 107 | NoneNoneNoneFMN A 201 (-3.3A) | 1.04A | 3twpD-5lvaA:undetectable | 3twpD-5lvaA:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mqo | NON-REDUCING ENDBETA-L-ARABINOFURANOSIDASE (Bacteroidesthetaiotaomicron) |
PF07944(Glyco_hydro_127) | 4 | ASN A 385ALA A 340TYR A 367ALA A 297 | None | 1.23A | 3twpD-5mqoA:2.9 | 3twpD-5mqoA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mso | CARBOXYLIC ACIDREDUCTASE (Mycobacteriummarinum) |
PF07993(NAD_binding_4) | 4 | ALA A1050PRO A 977TYR A 916ALA A 908 | None | 1.41A | 3twpD-5msoA:2.8 | 3twpD-5msoA:17.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ntf | AMINOPEPTIDASE (Trypanosomacruzi) |
PF00883(Peptidase_M17) | 4 | ASN A 217PRO A 215TYR A 176ALA A 167 | None | 1.04A | 3twpD-5ntfA:undetectable | 3twpD-5ntfA:23.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5suo | EXTRACELLULARSOLUTE-BINDINGPROTEIN (Streptococcuspneumoniae) |
PF12010(DUF3502) | 4 | ASN A 141ALA A 149PRO A 151ALA A 321 | None | 1.12A | 3twpD-5suoA:undetectable | 3twpD-5suoA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u2g | PENICILLIN-BINDINGPROTEIN 1A (Haemophilusinfluenzae) |
PF00905(Transpeptidase)PF00912(Transgly)PF17092(PCB_OB) | 4 | ASN A 307ALA A 775PRO A 774ALA A 738 | None | 0.96A | 3twpD-5u2gA:undetectable | 3twpD-5u2gA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ur0 | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Naegleriagruberi) |
no annotation | 4 | ASN A 145ALA A 123PRO A 122ALA A 213 | None | 1.33A | 3twpD-5ur0A:undetectable | 3twpD-5ur0A:10.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wro | ENOLASE (Drosophilamelanogaster) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | ASN A 228ALA A 281PRO A 282ALA A 290 | None | 1.42A | 3twpD-5wroA:undetectable | 3twpD-5wroA:24.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y9d | ACYL-COENZYME AOXIDASE 1 (Yarrowialipolytica) |
no annotation | 4 | ASN A 428ALA A 636PRO A 637TYR A 60 | None | 1.42A | 3twpD-5y9dA:undetectable | 3twpD-5y9dA:11.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yg7 | RIBOSE1,5-BISPHOSPHATEISOMERASE (Pyrococcushorikoshii) |
no annotation | 4 | ASN A 209ALA A 211PRO A 286ALA A 304 | G A 404 (-3.5A) G A 404 (-3.3A)NoneNone | 1.41A | 3twpD-5yg7A:undetectable | 3twpD-5yg7A:10.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zvt | CORE PROTEIN VP6 (Aquareovirus C) |
no annotation | 4 | ASN U 329PRO U 332TYR U 359ALA U 363 | None | 1.09A | 3twpD-5zvtU:undetectable | 3twpD-5zvtU:15.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6e0s | - (-) |
no annotation | 4 | ASN A 196ALA A 271TYR A 267ALA A 240 | None | 1.16A | 3twpD-6e0sA:undetectable | 3twpD-6e0sA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eoj | POLYADENYLATIONFACTOR SUBUNIT2,POLYADENYLATIONFACTOR SUBUNIT 2PROTEIN CFT1 (Saccharomycescerevisiae) |
no annotation | 5 | ASN D 69ALA D 70PRO D 67TYR D 43ALA A1143 | None | 1.37A | 3twpD-6eojD:undetectable | 3twpD-6eojD:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ey5 | T9SS COMPONENTCYTOPLASMIC MEMBRANEPROTEIN PORM (Porphyromonasgingivalis) |
no annotation | 4 | ASN A 334ALA A 366PRO A 368ALA A 375 | None | 1.41A | 3twpD-6ey5A:undetectable | 3twpD-6ey5A:12.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fks | - (-) |
no annotation | 4 | ALA A 290PRO A 291TYR A 170ALA A 73 | None | 1.41A | 3twpD-6fksA:undetectable | 3twpD-6fksA:undetectable |