SIMILAR PATTERNS OF AMINO ACIDS FOR 3TKD_A_CYZA266_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b63 | MUTL (Escherichiacoli) |
PF01119(DNA_mis_repair)PF13589(HATPase_c_3) | 4 | ILE A 54PRO A 23LYS A 52GLY A 50 | None | 1.06A | 3tkdB-1b63A:undetectable | 3tkdB-1b63A:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1crl | LIPASE (Diutina rugosa) |
PF00135(COesterase) | 4 | ILE A 26PRO A 27SER A 55GLY A 25 | None | 1.04A | 3tkdB-1crlA:undetectable | 3tkdB-1crlA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h79 | ANAEROBICRIBONUCLEOTIDE-TRIPHOSPHATE REDUCTASELARGE CHAIN (Escherichiavirus T4) |
PF13597(NRDD) | 4 | ILE A 402PRO A 320SER A 479GLY A 403 | None | 1.04A | 3tkdB-1h79A:undetectable | 3tkdB-1h79A:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j3n | 3-OXOACYL-(ACYL-CARRIER PROTEIN)SYNTHASE II (Thermusthermophilus) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 4 | PRO A 362SER A 31LYS A 30GLY A 29 | None | 1.17A | 3tkdB-1j3nA:undetectable | 3tkdB-1j3nA:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l0q | SURFACE LAYERPROTEIN (Methanosarcinamazei) |
PF00801(PKD)PF10282(Lactonase) | 4 | ILE A 295PRO A 253SER A 1GLY A 296 | None | 0.96A | 3tkdB-1l0qA:undetectable | 3tkdB-1l0qA:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mzr | 2,5-DIKETO-D-GLUCONATE REDUCTASE A (Escherichiacoli) |
PF00248(Aldo_ket_red) | 4 | ILE A 230SER A 233LYS A 232GLY A 22 | NonePO4 A 901 (-2.6A)NoneNone | 0.97A | 3tkdB-1mzrA:undetectable | 3tkdB-1mzrA:23.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pzt | BETA-1,4-GALACTOSYLTRANSFERASE 1 (Bos taurus) |
PF02709(Glyco_transf_7C)PF13733(Glyco_transf_7N) | 4 | ILE A 339PRO A 335LYS A 341GLY A 340 | None | 1.07A | 3tkdB-1pztA:undetectable | 3tkdB-1pztA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qjc | PHOSPHOPANTETHEINEADENYLYLTRANSFERASE (Escherichiacoli) |
PF01467(CTP_transf_like) | 4 | ILE A 21PRO A 120SER A 128GLY A 17 | NoneNoneSO4 A1161 (-4.8A)None | 1.10A | 3tkdB-1qjcA:undetectable | 3tkdB-1qjcA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r1a | HUMAN RHINOVIRUS 1ACOAT PROTEIN(SUBUNIT VP2) (Rhinovirus A) |
PF00073(Rhv) | 4 | ILE 2 225PRO 2 226SER 2 157GLY 2 77 | None | 1.15A | 3tkdB-1r1a2:undetectable | 3tkdB-1r1a2:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vbm | TYROSYL-TRNASYNTHETASE (Escherichiacoli) |
PF00579(tRNA-synt_1b) | 4 | ILE A 196PRO A 54SER A 199GLY A 197 | NoneYSA A3001 (-4.1A)NoneYSA A3001 (-3.6A) | 1.04A | 3tkdB-1vbmA:undetectable | 3tkdB-1vbmA:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zq7 | HYPOTHETICAL PROTEINMM0484 (Methanosarcinamazei) |
PF01871(AMMECR1) | 4 | ILE A 125PRO A 147LYS A 127GLY A 126 | None | 0.86A | 3tkdB-1zq7A:undetectable | 3tkdB-1zq7A:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aka | DYNAMIN-1 (Rattusnorvegicus) |
PF00350(Dynamin_N)PF01031(Dynamin_M) | 4 | ILE B 152PRO B 149SER B 116GLY B 114 | None | 0.98A | 3tkdB-2akaB:undetectable | 3tkdB-2akaB:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cy7 | CYSTEINE PROTEASEAPG4B (Homo sapiens) |
PF03416(Peptidase_C54) | 4 | ILE A 256PRO A 145SER A 262GLY A 257 | None | 1.02A | 3tkdB-2cy7A:undetectable | 3tkdB-2cy7A:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dmh | MYOFERLIN (Homo sapiens) |
PF00168(C2) | 4 | ILE A 64PRO A 65SER A 139GLY A 63 | None | 1.00A | 3tkdB-2dmhA:undetectable | 3tkdB-2dmhA:23.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e6n | STAPHYLOCOCCALNUCLEASEDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF00567(TUDOR) | 4 | ILE A 41PRO A 27SER A 78GLY A 82 | None | 1.07A | 3tkdB-2e6nA:undetectable | 3tkdB-2e6nA:15.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eoq | ZINC FINGER PROTEIN224 (Homo sapiens) |
no annotation | 4 | ILE A 17SER A 21LYS A 20GLY A 19 | ZN A 201 ( 4.2A)NoneNoneNone | 1.15A | 3tkdB-2eoqA:undetectable | 3tkdB-2eoqA:12.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q2e | TYPE 2 DNATOPOISOMERASE 6SUBUNIT B (Methanosarcinamazei) |
PF02518(HATPase_c)PF09239(Topo-VIb_trans) | 4 | ILE B 320PRO B 319SER B 341GLY B 321 | None | 1.11A | 3tkdB-2q2eB:undetectable | 3tkdB-2q2eB:17.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qlp | DEOXYCYTIDINETRIPHOSPHATEDEAMINASE (Mycobacteriumtuberculosis) |
PF00692(dUTPase) | 4 | ILE A 146SER A 102LYS A 101GLY A 147 | None | 0.97A | 3tkdB-2qlpA:undetectable | 3tkdB-2qlpA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qpm | CYTOKININDEHYDROGENASE 1 (Zea mays) |
PF01565(FAD_binding_4)PF09265(Cytokin-bind) | 4 | ILE A 184PRO A 193SER A 180GLY A 183 | FAD A1535 (-4.2A)NoneFAD A1535 (-3.2A)FAD A1535 (-3.3A) | 1.13A | 3tkdB-2qpmA:undetectable | 3tkdB-2qpmA:19.38 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2rcb | GLUTAMATE [NMDA]RECEPTOR SUBUNIT 3B (Rattusnorvegicus) |
PF10613(Lig_chan-Glu_bd) | 4 | ILE A 124PRO A 137SER A 121GLY A 251 | None | 1.14A | 3tkdB-2rcbA:30.3 | 3tkdB-2rcbA:30.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rdm | RESPONSE REGULATORRECEIVER PROTEIN (Sinorhizobiummedicae) |
PF00072(Response_reg) | 4 | ILE A 40PRO A 62SER A 34GLY A 36 | None | 1.18A | 3tkdB-2rdmA:undetectable | 3tkdB-2rdmA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x0s | PYRUVATE PHOSPHATEDIKINASE (Trypanosomabrucei) |
PF00391(PEP-utilizers)PF01326(PPDK_N)PF02896(PEP-utilizers_C) | 4 | ILE A 419SER A 526LYS A 527GLY A 528 | None | 1.15A | 3tkdB-2x0sA:undetectable | 3tkdB-2x0sA:14.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x5d | PROBABLEAMINOTRANSFERASE (Pseudomonasaeruginosa) |
PF00155(Aminotran_1_2) | 4 | ILE A 76PRO A 77SER A 73GLY A 75 | None | 1.18A | 3tkdB-2x5dA:undetectable | 3tkdB-2x5dA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xts | SULFITEDEHYDROGENASE (Paracoccuspantotrophus) |
PF00174(Oxidored_molyb)PF03404(Mo-co_dimer) | 4 | ILE A 413PRO A 393LYS A 395GLY A 412 | GOL A1432 (-4.0A)NoneNoneNone | 1.17A | 3tkdB-2xtsA:undetectable | 3tkdB-2xtsA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yy7 | L-THREONINEDEHYDROGENASE (Flavobacteriumfrigidimaris) |
PF01370(Epimerase) | 4 | ILE A 145PRO A 139SER A 80GLY A 144 | NoneNoneGOL A1001 (-3.6A)None | 1.14A | 3tkdB-2yy7A:undetectable | 3tkdB-2yy7A:21.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2zns | GLUTAMATE RECEPTOR,IONOTROPIC KAINATE 1 (Homo sapiens) |
PF10613(Lig_chan-Glu_bd) | 4 | ILE A 504PRO A 517LYS A 747GLY A 748 | None | 0.18A | 3tkdB-2znsA:37.7 | 3tkdB-2znsA:53.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cvo | METHYLTRANSFERASE-LIKE PROTEIN OFUNKNOWN FUNCTION (Ruegeriapomeroyi) |
no annotation | 4 | ILE A 88PRO A 97LYS A 102GLY A 89 | None | 1.13A | 3tkdB-3cvoA:undetectable | 3tkdB-3cvoA:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dhu | ALPHA-AMYLASE (Lactobacillusplantarum) |
PF00128(Alpha-amylase) | 4 | ILE A 54SER A 112LYS A 70GLY A 55 | None | 1.17A | 3tkdB-3dhuA:undetectable | 3tkdB-3dhuA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f7o | SERINE PROTEASE (Purpureocilliumlilacinum) |
PF00082(Peptidase_S8) | 4 | ILE A 268PRO A 269SER A 194GLY A 267 | None | 1.11A | 3tkdB-3f7oA:undetectable | 3tkdB-3f7oA:24.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g8y | SUSD/RAGB-ASSOCIATEDESTERASE-LIKEPROTEIN (Bacteroidesvulgatus) |
PF12715(Abhydrolase_7) | 4 | ILE A 143PRO A 261SER A 146GLY A 258 | None | 0.74A | 3tkdB-3g8yA:undetectable | 3tkdB-3g8yA:21.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3h6t | GLUTAMATE RECEPTOR 2 (Rattusnorvegicus) |
PF10613(Lig_chan-Glu_bd) | 5 | ILE A 92PRO A 105SER A 217LYS A 218GLY A 219 | NoneCYZ A 265 (-3.9A)GOL A 270 ( 3.0A)NoneNone | 0.18A | 3tkdB-3h6tA:42.7 | 3tkdB-3h6tA:99.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hzh | CHEMOTAXIS RESPONSEREGULATOR (CHEY-3) (Borreliellaburgdorferi) |
PF00072(Response_reg) | 4 | ILE A 18PRO A 25SER A 47GLY A 17 | None | 1.17A | 3tkdB-3hzhA:undetectable | 3tkdB-3hzhA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i9v | NADH-QUINONEOXIDOREDUCTASESUBUNIT 1NADH-QUINONEOXIDOREDUCTASESUBUNIT 2 (Thermusthermophilus) |
PF01257(2Fe-2S_thioredx)PF01512(Complex1_51K)PF10531(SLBB)PF10589(NADH_4Fe-4S) | 4 | ILE 1 254PRO 1 261SER 2 127GLY 1 262 | NoneNoneFES 2 182 (-4.4A)None | 1.14A | 3tkdB-3i9v1:undetectable | 3tkdB-3i9v1:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k8z | NAD-SPECIFICGLUTAMATEDEHYDROGENASE (Bacillussubtilis) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 4 | ILE A 82SER A 97LYS A 115GLY A 116 | None | 1.01A | 3tkdB-3k8zA:undetectable | 3tkdB-3k8zA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ka7 | OXIDOREDUCTASE (Methanosarcinamazei) |
PF01593(Amino_oxidase) | 4 | ILE A 198PRO A 191LYS A 196GLY A 197 | None | 1.17A | 3tkdB-3ka7A:undetectable | 3tkdB-3ka7A:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3la4 | UREASE (Canavaliaensiformis) |
PF00449(Urease_alpha)PF00547(Urease_gamma)PF00699(Urease_beta)PF01979(Amidohydro_1) | 4 | ILE A 481SER A 471LYS A 469GLY A 468 | NoneKCX A 490 ( 4.2A)NoneNone | 1.17A | 3tkdB-3la4A:undetectable | 3tkdB-3la4A:17.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lft | UNCHARACTERIZEDPROTEIN (Streptococcuspneumoniae) |
PF04392(ABC_sub_bind) | 5 | ILE A 282PRO A 166SER A 317LYS A 316GLY A 315 | None | 1.32A | 3tkdB-3lftA:undetectable | 3tkdB-3lftA:25.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m9g | PROTEIN KINASE (Staphylococcusaureus) |
PF03793(PASTA) | 4 | ILE A 383SER A 386LYS A 385GLY A 384 | None | 1.10A | 3tkdB-3m9gA:undetectable | 3tkdB-3m9gA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nnd | POSSIBLE SUBSTRATEBINDING PROTEIN OFABC TRANSPORTERSYSTEM (Rhodopseudomonaspalustris) |
no annotation | 4 | ILE B 147PRO B 249LYS B 149GLY B 148 | None | 0.76A | 3tkdB-3nndB:undetectable | 3tkdB-3nndB:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nuz | PUTATIVE ACETYLXYLAN ESTERASE (Bacteroidesfragilis) |
PF12715(Abhydrolase_7) | 4 | ILE A 143PRO A 261SER A 146GLY A 258 | None | 0.76A | 3tkdB-3nuzA:undetectable | 3tkdB-3nuzA:22.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nv9 | MALIC ENZYME (Entamoebahistolytica) |
PF00390(malic)PF03949(Malic_M) | 4 | ILE A 130PRO A 364LYS A 125GLY A 128 | None | 1.07A | 3tkdB-3nv9A:undetectable | 3tkdB-3nv9A:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o0k | ALDO/KETO REDUCTASE (Brucellaabortus) |
PF00248(Aldo_ket_red) | 4 | ILE A 247SER A 250LYS A 249GLY A 39 | None | 1.15A | 3tkdB-3o0kA:undetectable | 3tkdB-3o0kA:23.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pdx | TYROSINEAMINOTRANSFERASE (Mus musculus) |
PF00155(Aminotran_1_2) | 4 | ILE A 113PRO A 111SER A 117GLY A 114 | None | 1.01A | 3tkdB-3pdxA:undetectable | 3tkdB-3pdxA:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3py9 | PROTEIN KINASE (Staphylococcusaureus) |
PF03793(PASTA) | 4 | ILE A 13SER A 16LYS A 15GLY A 14 | None | 1.01A | 3tkdB-3py9A:undetectable | 3tkdB-3py9A:25.24 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3qxm | GLUTAMATE RECEPTORIONOTROPIC, KAINATE2 (Homo sapiens) |
PF10613(Lig_chan-Glu_bd) | 4 | ILE A 488PRO A 501LYS A 731GLY A 732 | None | 0.28A | 3tkdB-3qxmA:37.7 | 3tkdB-3qxmA:52.47 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3u92 | GLUTAMATE RECEPTOR,IONOTROPIC KAINATE 3 (Rattusnorvegicus) |
PF10613(Lig_chan-Glu_bd) | 4 | ILE A 91PRO A 104LYS A 213GLY A 214 | None | 0.31A | 3tkdB-3u92A:37.6 | 3tkdB-3u92A:52.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ukf | UDP-GALACTOPYRANOSEMUTASE (Aspergillusfumigatus) |
PF13450(NAD_binding_8) | 4 | ILE A 221PRO A 213SER A 48GLY A 220 | None | 1.14A | 3tkdB-3ukfA:undetectable | 3tkdB-3ukfA:19.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vsm | OCCLUSION-DERIVEDVIRUS ENVELOPEPROTEIN E66 (Autographacalifornicamultiplenucleopolyhedrovirus) |
PF04850(Baculo_E66) | 4 | ILE A 473SER A 370LYS A 371GLY A 386 | None | 0.80A | 3tkdB-3vsmA:undetectable | 3tkdB-3vsmA:17.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w36 | NAPH1 (Streptomycessp. CNQ525) |
no annotation | 4 | ILE A 303PRO A 380SER A 487GLY A 492 | None | 1.05A | 3tkdB-3w36A:undetectable | 3tkdB-3w36A:16.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wbx | PUTATIVE2,5-DIKETO-D-GLUCONIC ACID REDUCTASE (Gluconobacteroxydans) |
PF00248(Aldo_ket_red) | 4 | ILE A 205PRO A 216LYS A 207GLY A 206 | None | 1.16A | 3tkdB-3wbxA:undetectable | 3tkdB-3wbxA:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wbx | PUTATIVE2,5-DIKETO-D-GLUCONIC ACID REDUCTASE (Gluconobacteroxydans) |
PF00248(Aldo_ket_red) | 4 | ILE A 232SER A 235LYS A 234GLY A 28 | NoneNoneSO4 A 301 (-4.2A)None | 1.09A | 3tkdB-3wbxA:undetectable | 3tkdB-3wbxA:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wmx | NAD DEPENDENTEPIMERASE/DEHYDRATASE (Cupriavidusnecator) |
PF01370(Epimerase) | 4 | ILE A 146PRO A 140SER A 81GLY A 145 | NoneNoneTHR A 402 (-2.8A)None | 1.08A | 3tkdB-3wmxA:undetectable | 3tkdB-3wmxA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c1s | GLYCOSIDE HYDROLASEFAMILY 76MANNOSIDASE (Bacteroidesthetaiotaomicron) |
PF03663(Glyco_hydro_76) | 4 | ILE A 414PRO A 391SER A 385GLY A 389 | None | 1.15A | 3tkdB-4c1sA:undetectable | 3tkdB-4c1sA:19.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d3d | IMINE REDUCTASE (Bacillus cereus) |
PF03446(NAD_binding_2) | 4 | ILE A 145SER A 148LYS A 147GLY A 146 | None | 1.17A | 3tkdB-4d3dA:undetectable | 3tkdB-4d3dA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dsh | UDP-GALACTOPYRANOSEMUTASE (Trypanosomacruzi) |
PF01593(Amino_oxidase)PF13450(NAD_binding_8) | 4 | ILE A 214PRO A 207SER A 46GLY A 211 | NoneNoneFDA A 502 (-3.1A)None | 1.12A | 3tkdB-4dshA:undetectable | 3tkdB-4dshA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ej0 | ADP-L-GLYCERO-D-MANNO-HEPTOSE-6-EPIMERASE (Burkholderiathailandensis) |
PF01370(Epimerase) | 4 | ILE A 119PRO A 135LYS A 143GLY A 140 | NoneNoneNAP A 401 (-3.0A)None | 1.15A | 3tkdB-4ej0A:undetectable | 3tkdB-4ej0A:23.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fzi | PROSTAGLANDIN FSYNTHASE (Trypanosomacruzi) |
PF00248(Aldo_ket_red) | 4 | ILE A 232SER A 235LYS A 234GLY A 22 | None | 0.85A | 3tkdB-4fziA:undetectable | 3tkdB-4fziA:22.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ghk | GAMMA-GLUTAMYLPHOSPHATE REDUCTASE (Burkholderiathailandensis) |
PF00171(Aldedh) | 4 | ILE A 95PRO A 116SER A 20GLY A 142 | None | 1.19A | 3tkdB-4ghkA:undetectable | 3tkdB-4ghkA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4igl | YENB (Yersiniaentomophaga) |
PF03534(SpvB)PF12255(TcdB_toxin_midC)PF12256(TcdB_toxin_midN) | 4 | ILE A1255PRO A1253SER A1345GLY A1254 | None | 1.14A | 3tkdB-4iglA:undetectable | 3tkdB-4iglA:11.13 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4kcd | GLUTAMATE RECEPTORIONOTROPIC, NMDA 3A (Rattusnorvegicus) |
PF10613(Lig_chan-Glu_bd) | 4 | ILE A 126PRO A 139SER A 123GLY A 253 | None | 1.11A | 3tkdB-4kcdA:29.7 | 3tkdB-4kcdA:30.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4kcd | GLUTAMATE RECEPTORIONOTROPIC, NMDA 3A (Rattusnorvegicus) |
PF10613(Lig_chan-Glu_bd) | 4 | ILE A 126PRO A 139SER A 144GLY A 251 | None | 1.02A | 3tkdB-4kcdA:29.7 | 3tkdB-4kcdA:30.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lmh | EXTRACELLULAR IRONOXIDE RESPIRATORYSYSTEM SURFACEDECAHEME CYTOCHROMEC COMPONENT OMCA (Shewanellaoneidensis) |
no annotation | 4 | ILE A 299PRO A 129LYS A 304GLY A 303 | NoneNoneHEC A 802 ( 4.4A)None | 1.11A | 3tkdB-4lmhA:undetectable | 3tkdB-4lmhA:15.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oal | CYTOKININDEHYDROGENASE 4 (Zea mays) |
PF01565(FAD_binding_4)PF09265(Cytokin-bind) | 4 | ILE A 185PRO A 194SER A 181GLY A 184 | FAD A 601 (-4.3A)NoneFAD A 601 (-3.1A)FAD A 601 (-3.3A) | 1.13A | 3tkdB-4oalA:undetectable | 3tkdB-4oalA:17.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pkv | LETHAL FACTOR (Bacillusanthracis) |
PF07737(ATLF)PF09156(Anthrax-tox_M) | 4 | ILE A 525SER A 553LYS A 552GLY A 526 | None | 0.91A | 3tkdB-4pkvA:undetectable | 3tkdB-4pkvA:18.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u1r | ATP-DEPENDENT6-PHOSPHOFRUCTOKINASE, PLATELET TYPE (Homo sapiens) |
PF00365(PFK) | 4 | ILE A 689PRO A 536SER A 723GLY A 721 | None | 0.98A | 3tkdB-4u1rA:undetectable | 3tkdB-4u1rA:16.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wl2 | PUTATIVE EXPORTEDCHOLOYLGLYCINEHYDROLASE (Pectobacteriumatrosepticum) |
PF02275(CBAH) | 4 | ILE A 134PRO A 98SER A 106GLY A 104 | None | 0.87A | 3tkdB-4wl2A:undetectable | 3tkdB-4wl2A:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xox | 3-OXOACYL-ACPSYNTHASE (Vibrio cholerae) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 4 | PRO A 354SER A 31LYS A 30GLY A 29 | None | 1.17A | 3tkdB-4xoxA:undetectable | 3tkdB-4xoxA:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yji | ARYL ACYLAMIDASE (bacteriumCSBL00001) |
PF01425(Amidase) | 4 | ILE A 16PRO A 80SER A 26GLY A 78 | None | 1.11A | 3tkdB-4yjiA:2.4 | 3tkdB-4yjiA:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zfm | PUTATIVE6-PHOSPHO-BETA-GALACTOBIOSIDASE (Geobacillusstearothermophilus) |
PF00232(Glyco_hydro_1) | 4 | ILE A 209PRO A 293SER A 224GLY A 222 | None | 1.00A | 3tkdB-4zfmA:undetectable | 3tkdB-4zfmA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zrm | UDP-GLUCOSE4-EPIMERASE (Thermotogamaritima) |
PF01370(Epimerase) | 4 | ILE A 121PRO A 139LYS A 147GLY A 144 | NoneNoneNAD A 401 (-2.8A)None | 0.96A | 3tkdB-4zrmA:undetectable | 3tkdB-4zrmA:24.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5but | KTR SYSTEM POTASSIUMUPTAKE PROTEIN B (Bacillussubtilis) |
PF02386(TrkH) | 4 | ILE I 418PRO I 420SER I 312GLY I 416 | None | 1.16A | 3tkdB-5butI:undetectable | 3tkdB-5butI:18.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cfk | PROLIFERATING CELLNUCLEARANTIGEN,PROLIFERATING CELL NUCLEARANTIGEN (Leishmaniadonovani) |
PF00705(PCNA_N)PF02747(PCNA_C) | 4 | ILE A 128PRO A 129SER A 125GLY A 127 | None | 1.06A | 3tkdB-5cfkA:undetectable | 3tkdB-5cfkA:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ch6 | FRIGIDA (Vitis vinifera) |
PF07899(Frigida) | 4 | ILE A 246PRO A 247SER A 243GLY A 245 | None | 1.13A | 3tkdB-5ch6A:undetectable | 3tkdB-5ch6A:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d9a | POLYMERASE ACIDICPROTEIN (Influenza Cvirus) |
PF00603(Flu_PA) | 4 | ILE A 238PRO A 667SER A 662GLY A 664 | None | 0.98A | 3tkdB-5d9aA:undetectable | 3tkdB-5d9aA:15.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5deu | METHYLCYTOSINEDIOXYGENASE TET2,CHIMERIC CONSTRUCT (Homo sapiens) |
PF12851(Tet_JBP) | 4 | ILE A1859SER A1189LYS A1188GLY A1187 | None | 1.08A | 3tkdB-5deuA:undetectable | 3tkdB-5deuA:18.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e02 | FRQ-INTERACTING RNAHELICASE (Neurosporacrassa) |
PF00270(DEAD)PF00271(Helicase_C)PF08148(DSHCT)PF13234(rRNA_proc-arch) | 4 | ILE A 777SER A 784LYS A 782GLY A 781 | None | 1.18A | 3tkdB-5e02A:undetectable | 3tkdB-5e02A:12.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e05 | NUCLEOCAPSID PROTEIN (Sin Nombreorthohantavirus) |
PF00846(Hanta_nucleocap) | 4 | ILE A 280PRO A 316SER A 121LYS A 120 | None | 0.71A | 3tkdB-5e05A:undetectable | 3tkdB-5e05A:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fby | SEPARASE (Chaetomiumthermophilum) |
PF03568(Peptidase_C50) | 4 | ILE A2077PRO A2076SER A2054GLY A2024 | None | 0.94A | 3tkdB-5fbyA:undetectable | 3tkdB-5fbyA:18.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h29 | THIOREDOXINREDUCTASE/GLUTATHIONE-RELATED PROTEIN (Enterococcusfaecalis) |
no annotation | 4 | ILE A 446PRO A 447SER A 428GLY A 445 | None | 1.13A | 3tkdB-5h29A:undetectable | 3tkdB-5h29A:17.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h6s | AMIDASE (Microbacteriumsp. HM58-2) |
PF01425(Amidase) | 4 | ILE A 13PRO A 76SER A 23GLY A 74 | None | 1.18A | 3tkdB-5h6sA:undetectable | 3tkdB-5h6sA:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i6g | ACETYL-COACARBOXYLASE-LIKEPROTEIN,ACETYL-COACARBOXYLASE-LIKEPROTEIN (Chaetomiumthermophilum) |
PF01039(Carboxyl_trans)PF08326(ACC_central) | 4 | ILE A1928PRO A1929SER A1862GLY A1927 | None | 1.08A | 3tkdB-5i6gA:undetectable | 3tkdB-5i6gA:13.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i6h | ACETYL-COACARBOXYLASE-LIKEPROTEIN (Chaetomiumthermophilum) |
PF01039(Carboxyl_trans)PF08326(ACC_central) | 4 | ILE A1928PRO A1929SER A1862GLY A1927 | None | 1.09A | 3tkdB-5i6hA:undetectable | 3tkdB-5i6hA:10.64 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ict | GLUTAMATE RECEPTOR 1 (Drosophilamelanogaster) |
PF10613(Lig_chan-Glu_bd) | 4 | ILE A 98PRO A 111LYS A 223GLY A 224 | None | 0.22A | 3tkdB-5ictA:38.6 | 3tkdB-5ictA:56.34 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ikb | GLUTAMATE RECEPTORIONOTROPIC, KAINATE4,GLUTAMATE RECEPTORIONOTROPIC, KAINATE4 (Rattusnorvegicus) |
PF10613(Lig_chan-Glu_bd) | 4 | ILE A 91PRO A 104LYS A 214GLY A 215 | None | 0.39A | 3tkdB-5ikbA:36.7 | 3tkdB-5ikbA:55.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5im4 | PHOSPHOTRANSFERASESYSTEM,MANNOSE/FRUCTOSE-SPECIFIC COMPONENT IIA (Caldanaerobactersubterraneus) |
PF03610(EIIA-man) | 4 | ILE F 121PRO F 97LYS F 123GLY F 122 | None | 1.17A | 3tkdB-5im4F:2.5 | 3tkdB-5im4F:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jz7 | MEDI578 SCFV, HEAVYCHAIN (Homo sapiens) |
PF07686(V-set) | 4 | ILE C 52PRO C 52SER C 96GLY C 33 | None | 1.17A | 3tkdB-5jz7C:undetectable | 3tkdB-5jz7C:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kju | SHIKIMATEO-HYDROXYCINNAMOYLTRANSFERASE (Arabidopsisthaliana) |
PF02458(Transferase) | 4 | ILE A 394PRO A 395SER A 38GLY A 393 | NoneNone6TO A 800 ( 4.3A)None | 0.88A | 3tkdB-5kjuA:undetectable | 3tkdB-5kjuA:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kuf | GLUTAMATE RECEPTORIONOTROPIC, KAINATE2 (Rattusnorvegicus) |
PF00060(Lig_chan)PF01094(ANF_receptor)PF10613(Lig_chan-Glu_bd) | 4 | ILE A 488PRO A 501LYS A 731GLY A 732 | None | 0.70A | 3tkdB-5kufA:35.0 | 3tkdB-5kufA:19.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5l1b | GLUTAMATE RECEPTOR2,GLUTAMATE RECEPTOR2 (Rattusnorvegicus) |
PF00060(Lig_chan)PF01094(ANF_receptor)PF10613(Lig_chan-Glu_bd) | 4 | ILE A 481PRO A 494LYS A 730GLY A 731 | None | 0.53A | 3tkdB-5l1bA:21.7 | 3tkdB-5l1bA:34.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5low | RABPHILIN-3A (Rattusnorvegicus) |
PF00168(C2) | 4 | ILE A 634SER A 637LYS A 636GLY A 635 | NoneNone CA A 703 ( 3.8A)None | 1.02A | 3tkdB-5lowA:undetectable | 3tkdB-5lowA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mb4 | GLCNAC SPECIFICLECTIN (Psathyrella) |
PF13517(VCBS) | 4 | ILE A 15PRO A 16SER A 291GLY A 348 | None | 1.19A | 3tkdB-5mb4A:undetectable | 3tkdB-5mb4A:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5na7 | PUTATIVEDIPEPTIDYL-PEPTIDASEIII (Bacteroidesthetaiotaomicron) |
no annotation | 4 | ILE A 36PRO A 378LYS A 628GLY A 629 | None | 1.10A | 3tkdB-5na7A:undetectable | 3tkdB-5na7A:18.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tos | SERINE/THREONINE-PROTEIN KINASE BIK1 (Arabidopsisthaliana) |
no annotation | 4 | ILE A 137SER A 54LYS A 52GLY A 138 | None | 1.17A | 3tkdB-5tosA:undetectable | 3tkdB-5tosA:17.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uff | RBC36 (Petromyzonmarinus) |
no annotation | 4 | ILE A 47PRO A 48SER A 24GLY A 46 | None | 1.18A | 3tkdB-5uffA:undetectable | 3tkdB-5uffA:18.38 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5wel | CHIMERA OF GLUTAMATERECEPTOR 2, GERMCELL-SPECIFIC GENE1-LIKE PROTEIN (Mus musculus;Rattusnorvegicus) |
PF00060(Lig_chan)PF01094(ANF_receptor)PF07803(GSG-1)PF10613(Lig_chan-Glu_bd) | 5 | ILE A 481PRO A 494SER A 729LYS A 730GLY A 731 | None | 0.85A | 3tkdB-5welA:31.6 | 3tkdB-5welA:33.90 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5weo | GLUTAMATE RECEPTOR2,VOLTAGE-DEPENDENTCALCIUM CHANNELGAMMA-2 SUBUNITCHIMERA (Mus musculus;Rattusnorvegicus) |
PF00060(Lig_chan)PF00822(PMP22_Claudin)PF01094(ANF_receptor)PF10613(Lig_chan-Glu_bd) | 5 | ILE A 481PRO A 494SER A 729LYS A 730GLY A 731 | NoneCYZ A1302 (-4.5A)NoneGLU A1301 ( 3.7A)None | 0.61A | 3tkdB-5weoA:24.5 | 3tkdB-5weoA:33.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x6x | MRNA CAPPING ENZYMEP5 (Rice dwarfvirus) |
no annotation | 4 | ILE C 229SER C 232LYS C 231GLY C 470 | None | 1.07A | 3tkdB-5x6xC:undetectable | 3tkdB-5x6xC:15.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xtg | 2,3-DIHYDROXY-2,3-DIHYDROPHENYLPROPIONATE DEHYDROGENASE (Pseudomonas sp.MC1) |
PF13561(adh_short_C2) | 4 | ILE B 16PRO B 224SER B 188GLY B 15 | NAD B 301 (-3.7A)NoneBPY B 303 ( 4.9A)NAD B 301 (-3.2A) | 1.12A | 3tkdB-5xtgB:undetectable | 3tkdB-5xtgB:25.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y3r | X-RAY REPAIRCROSS-COMPLEMENTINGPROTEIN 5 (Homo sapiens) |
PF02735(Ku)PF03730(Ku_C)PF03731(Ku_N) | 4 | ILE B 482PRO B 483SER B 230LYS B 233 | None | 1.19A | 3tkdB-5y3rB:undetectable | 3tkdB-5y3rB:18.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cfw | MONOVALENT CATION/H+ANTIPORTER SUBUNIT EMONOVALENT CATION/H+ANTIPORTER SUBUNIT G (Pyrococcusfuriosus) |
no annotation | 4 | PRO C 67SER A 27LYS A 22GLY A 23 | None | 1.14A | 3tkdB-6cfwC:undetectable | 3tkdB-6cfwC:15.85 |