SIMILAR PATTERNS OF AMINO ACIDS FOR 3TGV_D_BEZD1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bdg HEXOKINASE

(Schistosoma
mansoni) 		PF00349
(Hexokinase_1)
PF03727
(Hexokinase_2) 		4 GLN A 276
PHE A  29
PRO A  28
LEU A  26
 None
 0.92A 3tgvD-1bdgA:
0.0		 3tgvD-1bdgA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dgs DNA LIGASE

(Thermus
filiformis) 		PF01653
(DNA_ligase_aden)
PF03120
(DNA_ligase_OB)
PF12826
(HHH_2)
PF14520
(HHH_5) 		4 ARG A 214
GLN A 205
PHE A 192
LEU A 184
 None
 1.36A 3tgvD-1dgsA:
0.0		 3tgvD-1dgsA:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mt0 HEMOLYSIN SECRETION
ATP-BINDING PROTEIN

(Escherichia
coli) 		PF00005
(ABC_tran) 		4 TYR A 519
PHE A 475
PRO A 521
LEU A 485
 None
 1.33A 3tgvD-1mt0A:
0.0		 3tgvD-1mt0A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mu2 HIV-2 RT

(Human
immunodeficiency
virus 2) 		PF00078
(RVT_1)
PF06815
(RVT_connect)
PF06817
(RVT_thumb) 		4 GLN B 372
PHE B 388
PRO B 411
LEU B 390
 None
 0.99A 3tgvD-1mu2B:
0.0		 3tgvD-1mu2B:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qu2 ISOLEUCYL-TRNA
SYNTHETASE

(Staphylococcus
aureus) 		PF00133
(tRNA-synt_1)
PF06827
(zf-FPG_IleRS)
PF08264
(Anticodon_1) 		4 GLN A  84
TYR A  80
PRO A 758
LEU A 755
 None
 1.21A 3tgvD-1qu2A:
undetectable		 3tgvD-1qu2A:
10.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)

(Rhinovirus A;
Rhinovirus A) 		PF00073
(Rhv)
PF00073
(Rhv) 		4 ARG 1 111
TYR 3 105
PHE 1  70
LEU 1 115
 None
 1.39A 3tgvD-1r1a1:
0.0		 3tgvD-1r1a1:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sn2 TRANSTHYRETIN

(Sparus aurata) 		PF00576
(Transthyretin) 		4 GLN A  34
TYR A  69
PHE A  64
PRO A  99
 None
 1.32A 3tgvD-1sn2A:
0.0		 3tgvD-1sn2A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uok OLIGO-1,6-GLUCOSIDAS
E

(Bacillus cereus) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		4 GLN A 150
TYR A 159
PHE A 111
PRO A 168
 None
 1.23A 3tgvD-1uokA:
0.0		 3tgvD-1uokA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yob FLAVODOXIN 2

(Azotobacter
vinelandii) 		PF00258
(Flavodoxin_1) 		4 GLN A  46
TYR A  47
PHE A   6
LEU A  34
 None
 1.30A 3tgvD-1yobA:
undetectable		 3tgvD-1yobA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zun SULFATE ADENYLATE
TRANSFERASE, SUBUNIT
1/ADENYLYLSULFATE
KINASE

(Pseudomonas
syringae group
genomosp. 3) 		PF00009
(GTP_EFTU) 		4 GLN B 249
PHE B 246
PRO B 247
LEU B 265
 None
 1.21A 3tgvD-1zunB:
undetectable		 3tgvD-1zunB:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bfe 2-OXOISOVALERATE
DEHYDROGENASE ALPHA
SUBUNIT

(Homo sapiens) 		PF00676
(E1_dh) 		4 GLN A 326
TYR A 322
PHE A 259
LEU A  52
 None
 1.39A 3tgvD-2bfeA:
undetectable		 3tgvD-2bfeA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bgh VINORINE SYNTHASE

(Rauvolfia
serpentina) 		PF02458
(Transferase) 		4 GLN A 120
TYR A 121
PHE A  45
LEU A 105
 None
 1.27A 3tgvD-2bghA:
undetectable		 3tgvD-2bghA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c1o IGK-C PROTEIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 ARG A  39
PHE A  62
PRO A  59
LEU A  47
 None
 1.21A 3tgvD-2c1oA:
undetectable		 3tgvD-2c1oA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f6d GLUCOAMYLASE GLU1

(Saccharomycopsis
fibuligera) 		PF00723
(Glyco_hydro_15) 		4 ARG A  69
GLN A 143
PRO A 147
LEU A 149
 ACR  A 995 (-3.7A)
None
None
None
 1.24A 3tgvD-2f6dA:
undetectable		 3tgvD-2f6dA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG

(Homo sapiens) 		PF04078
(Rcd1) 		4 TYR A  58
PHE A 106
PRO A 105
LEU A 103
 None
 1.20A 3tgvD-2fv2A:
undetectable		 3tgvD-2fv2A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2huo INOSITOL OXYGENASE

(Mus musculus) 		PF05153
(MIOX) 		4 GLN A 151
PHE A 222
PRO A 145
LEU A 185
 None
 1.24A 3tgvD-2huoA:
undetectable		 3tgvD-2huoA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ibn INOSITOL OXYGENASE

(Homo sapiens) 		PF05153
(MIOX) 		4 GLN A 151
PHE A 222
PRO A 145
LEU A 185
 None
 1.21A 3tgvD-2ibnA:
undetectable		 3tgvD-2ibnA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iwg 52 KDA RO PROTEIN

(Homo sapiens) 		PF00622
(SPRY)
PF13765
(PRY) 		4 ARG B  24
PHE B 163
PRO B 161
LEU B   8
 None
 1.26A 3tgvD-2iwgB:
undetectable		 3tgvD-2iwgB:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k8q PROTEIN SHQ1

(Saccharomyces
cerevisiae) 		no annotation 4 GLN A  10
PHE A  53
PRO A  54
LEU A  96
 None
 1.33A 3tgvD-2k8qA:
undetectable		 3tgvD-2k8qA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ksi STEROL CARRIER
PROTEIN 2

(Aedes aegypti) 		PF02036
(SCP2) 		4 GLN A  25
PHE A 105
PRO A 104
LEU A 102
 None
PLM  A 200 (-3.0A)
None
PLM  A 200 (-2.8A)
 1.11A 3tgvD-2ksiA:
undetectable		 3tgvD-2ksiA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ly9 ZINC FINGERS AND
HOMEOBOXES PROTEIN 1

(Homo sapiens) 		PF00046
(Homeobox) 		4 ARG A  58
GLN A  29
TYR A  25
PRO A  31
 None
 1.36A 3tgvD-2ly9A:
undetectable		 3tgvD-2ly9A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mk5 ENDOLYSIN

(Staphylococcus
virus G15) 		PF08460
(SH3_5) 		4 GLN A  41
TYR A  42
PHE A  68
PRO A  67
 None
 1.29A 3tgvD-2mk5A:
undetectable		 3tgvD-2mk5A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qlv PROTEIN SIP2

(Saccharomyces
cerevisiae) 		PF04739
(AMPKBI)
PF16561
(AMPK1_CBM) 		4 ARG B 169
GLN B 171
PHE B 217
LEU B 192
 None
 1.32A 3tgvD-2qlvB:
undetectable		 3tgvD-2qlvB:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qor GUANYLATE KINASE

(Plasmodium
vivax) 		PF00625
(Guanylate_kin) 		4 TYR A  88
PHE A 100
PRO A   6
LEU A 110
 None
 1.42A 3tgvD-2qorA:
undetectable		 3tgvD-2qorA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rau PUTATIVE ESTERASE

(Sulfolobus
solfataricus) 		PF12146
(Hydrolase_4) 		4 ARG A 210
PHE A 240
PRO A 230
LEU A 241
 PG4  A 358 (-3.7A)
PG4  A 358 (-4.5A)
PG4  A 358 (-4.3A)
None
 1.37A 3tgvD-2rauA:
undetectable		 3tgvD-2rauA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uv8 FATTY ACID SYNTHASE
SUBUNIT BETA (FAS1)

(Saccharomyces
cerevisiae) 		PF00698
(Acyl_transf_1)
PF01575
(MaoC_dehydratas)
PF08354
(DUF1729)
PF13452
(MaoC_dehydrat_N)
PF16073
(SAT) 		4 GLN G1088
TYR G1089
PRO G 567
LEU G 562
 None
 0.88A 3tgvD-2uv8G:
undetectable		 3tgvD-2uv8G:
5.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2van DNA POLYMERSE BETA

(Rattus
norvegicus) 		PF10391
(DNA_pol_lambd_f)
PF14791
(DNA_pol_B_thumb)
PF14792
(DNA_pol_B_palm) 		4 GLN A 317
TYR A 327
PRO A 330
LEU A 270
 None
 1.34A 3tgvD-2vanA:
undetectable		 3tgvD-2vanA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vuw SERINE/THREONINE-PRO
TEIN KINASE HASPIN

(Homo sapiens) 		PF12330
(Haspin_kinase) 		4 TYR A 569
PHE A 475
PRO A 570
LEU A 479
 None
 1.37A 3tgvD-2vuwA:
undetectable		 3tgvD-2vuwA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ww2 ALPHA-1,2-MANNOSIDAS
E

(Bacteroides
thetaiotaomicron) 		PF07971
(Glyco_hydro_92) 		4 GLN A 142
PHE A  85
PRO A 105
LEU A 145
 None
 1.30A 3tgvD-2ww2A:
undetectable		 3tgvD-2ww2A:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wz9 GLUTAREDOXIN-3

(Homo sapiens) 		PF00085
(Thioredoxin) 		4 GLN A  48
PHE A  88
PRO A  86
LEU A 100
 None
 0.98A 3tgvD-2wz9A:
undetectable		 3tgvD-2wz9A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xdq LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Thermosynechococcus
elongatus) 		PF00148
(Oxidored_nitro) 		4 GLN A 266
TYR A 244
PHE A 290
PRO A 197
 None
 0.99A 3tgvD-2xdqA:
undetectable		 3tgvD-2xdqA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yb6 UBIQUITIN-CONJUGATIN
G ENZYME E2 B

(Homo sapiens) 		PF00179
(UQ_con) 		4 TYR A 137
PHE A  48
PRO A  47
LEU A 113
 None
 1.41A 3tgvD-2yb6A:
undetectable		 3tgvD-2yb6A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yoi LECA THIOREDOXIN

(synthetic
construct) 		PF00085
(Thioredoxin) 		4 GLN A  94
PHE A  77
PRO A  75
LEU A  89
 None
 1.35A 3tgvD-2yoiA:
undetectable		 3tgvD-2yoiA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zkt 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE

(Pyrococcus
horikoshii) 		PF01676
(Metalloenzyme)
PF10143
(PhosphMutase) 		4 TYR A 231
PHE A  81
PRO A 232
LEU A  85
 None
 1.19A 3tgvD-2zktA:
undetectable		 3tgvD-2zktA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ay5 CYCLIN-D1-BINDING
PROTEIN 1

(Homo sapiens) 		PF13324
(GCIP) 		4 GLN A  20
PHE A  74
PRO A  80
LEU A  70
 None
 1.40A 3tgvD-3ay5A:
undetectable		 3tgvD-3ay5A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c2b TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY

(Agrobacterium
fabrum) 		PF00440
(TetR_N) 		4 ARG A 134
TYR A 163
PHE A  94
LEU A  98
 FMT  A 302 (-3.3A)
FMT  A 302 ( 4.2A)
None
None
 1.36A 3tgvD-3c2bA:
undetectable		 3tgvD-3c2bA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3feu PUTATIVE LIPOPROTEIN

(Aliivibrio
fischeri) 		PF13462
(Thioredoxin_4) 		4 GLN A  76
PHE A  85
PRO A  81
LEU A  89
 None
 1.38A 3tgvD-3feuA:
undetectable		 3tgvD-3feuA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g7j GLUTATHIONE
TRANSFERASE GST1-4

(Anopheles dirus) 		PF02798
(GST_N)
PF13410
(GST_C_2) 		4 GLN A  70
PHE A   3
PRO A  53
LEU A  55
 None
None
GTX  A 220 (-4.3A)
None
 1.23A 3tgvD-3g7jA:
undetectable		 3tgvD-3g7jA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gm5 LACTOYLGLUTATHIONE
LYASE AND RELATED
LYASES

(Caldanaerobacter
subterraneus) 		PF13669
(Glyoxalase_4) 		4 GLN A  26
PHE A  66
PRO A  37
LEU A  75
 None
 1.36A 3tgvD-3gm5A:
undetectable		 3tgvD-3gm5A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3icf SERINE/THREONINE-PRO
TEIN PHOSPHATASE T

(Saccharomyces
cerevisiae) 		PF00149
(Metallophos)
PF08321
(PPP5) 		4 GLN A 381
PHE A 388
PRO A 383
LEU A 392
 None
 1.40A 3tgvD-3icfA:
undetectable		 3tgvD-3icfA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ie1 RIBONUCLEASE
TTHA0252

(Thermus
thermophilus) 		PF00753
(Lactamase_B)
PF07521
(RMMBL)
PF10996
(Beta-Casp) 		4 GLN A 229
TYR A 261
PHE A 268
LEU A 171
 None
 0.92A 3tgvD-3ie1A:
undetectable		 3tgvD-3ie1A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k70 EXODEOXYRIBONUCLEASE
V ALPHA CHAIN

(Escherichia
coli) 		PF13538
(UvrD_C_2)
PF13604
(AAA_30) 		4 ARG D 557
PHE D 449
PRO D 448
LEU D 444
 None
 0.97A 3tgvD-3k70D:
undetectable		 3tgvD-3k70D:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lwt PHOSPHOINOSITIDE
PHOSPHATASE SAC1

(Saccharomyces
cerevisiae) 		PF02383
(Syja_N) 		4 ARG X  39
GLN X  34
PHE X  15
LEU X  41
 None
 1.43A 3tgvD-3lwtX:
undetectable		 3tgvD-3lwtX:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ml0 PENICILLIN G
ACYLASE, ALPHA
SUBUNIT
PENICILLIN G
ACYLASE, BETA
SUBUNIT

(Alcaligenes
faecalis;
Alcaligenes
faecalis) 		PF01804
(Penicil_amidase)
PF01804
(Penicil_amidase) 		4 ARG A 146
TYR B  31
PHE B  50
PRO B  49
 None
 1.37A 3tgvD-3ml0A:
undetectable		 3tgvD-3ml0A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mn8 LP15968P

(Drosophila
melanogaster) 		PF00246
(Peptidase_M14)
PF13620
(CarboxypepD_reg) 		4 GLN A  79
TYR A 138
PHE A 210
PRO A  93
 None
 1.05A 3tgvD-3mn8A:
undetectable		 3tgvD-3mn8A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mop INTERLEUKIN-1
RECEPTOR-ASSOCIATED
KINASE 4
INTERLEUKIN-1
RECEPTOR-ASSOCIATED
KINASE-LIKE 2

(Homo sapiens;
Homo sapiens) 		no annotation
PF00531
(Death) 		4 GLN K   7
TYR K   6
PHE G  25
LEU G  99
 None
 1.35A 3tgvD-3mopK:
undetectable		 3tgvD-3mopK:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mux PUTATIVE
4-HYDROXY-2-OXOGLUTA
RATE ALDOLASE

(Bacillus
anthracis) 		PF07071
(KDGP_aldolase) 		4 ARG A 205
GLN A 249
TYR A 250
LEU A 204
 None
 1.38A 3tgvD-3muxA:
undetectable		 3tgvD-3muxA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mvj CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA

(Homo sapiens) 		PF00069
(Pkinase) 		4 GLN A 307
PHE A 102
PRO A 101
LEU A 152
 None
 1.23A 3tgvD-3mvjA:
undetectable		 3tgvD-3mvjA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ogr BETA-GALACTOSIDASE

(Trichoderma
reesei) 		PF01301
(Glyco_hydro_35)
PF10435
(BetaGal_dom2)
PF13363
(BetaGal_dom3)
PF13364
(BetaGal_dom4_5) 		4 GLN A 947
TYR A 942
PHE A 867
LEU A 865
 None
 1.38A 3tgvD-3ogrA:
undetectable		 3tgvD-3ogrA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p8c NCK-ASSOCIATED
PROTEIN 1

(Homo sapiens) 		PF09735
(Nckap1) 		4 GLN B1038
PHE B1097
PRO B1096
LEU B1055
 None
 1.34A 3tgvD-3p8cB:
undetectable		 3tgvD-3p8cB:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rg2 ENTEROBACTIN
SYNTHASE COMPONENT E
(ENTE),
2,3-DIHYDRO-2,3-DIHY
DROXYBENZOATE
SYNTHETASE,
ISOCHROISMATASE
(ENTB)

(Escherichia
coli) 		PF00501
(AMP-binding)
PF00550
(PP-binding)
PF13193
(AMP-binding_C) 		4 GLN A 188
TYR A 186
PHE A  90
LEU A  86
 None
 1.36A 3tgvD-3rg2A:
undetectable		 3tgvD-3rg2A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t0y RESPONSE REGULATOR
NEPR

(Caulobacter
vibrioides;
Caulobacter
vibrioides) 		no annotation
no annotation 		4 GLN A  39
PHE B  54
PRO B  51
LEU A  25
 None
 1.28A 3tgvD-3t0yA:
undetectable		 3tgvD-3t0yA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t32 AMINOTRANSFERASE,
CLASS I/II

(Bacillus
anthracis) 		PF00155
(Aminotran_1_2) 		4 GLN A 274
PHE A  87
PRO A  60
LEU A 265
 None
 1.38A 3tgvD-3t32A:
undetectable		 3tgvD-3t32A:
17.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3tgv HEME-BINDING PROTEIN
HUTZ

(Vibrio cholerae) 		PF01243
(Putative_PNPOx) 		6 ARG A  22
GLN A  48
TYR A  53
PHE A  95
PRO A 140
LEU A 144
 None
 0.60A 3tgvD-3tgvA:
27.2		 3tgvD-3tgvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3tgv HEME-BINDING PROTEIN
HUTZ

(Vibrio cholerae) 		PF01243
(Putative_PNPOx) 		4 GLN A  48
TYR A  53
PHE A  95
LEU A  93
 None
 1.34A 3tgvD-3tgvA:
27.2		 3tgvD-3tgvA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zo0 E3 UBIQUITIN-PROTEIN
LIGASE TRIM21

(Mus musculus) 		PF00622
(SPRY)
PF13765
(PRY) 		4 ARG B  29
PHE B 167
PRO B 165
LEU B  13
 None
 1.29A 3tgvD-3zo0B:
undetectable		 3tgvD-3zo0B:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4az1 TYROSINE SPECIFIC
PROTEIN PHOSPHATASE

(Trypanosoma
cruzi) 		PF00102
(Y_phosphatase) 		4 GLN A 188
PHE A 104
PRO A  96
LEU A 105
 None
FMT  A1306 ( 4.8A)
FMT  A1306 (-3.8A)
None
 1.26A 3tgvD-4az1A:
undetectable		 3tgvD-4az1A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bqn CAPSULAR
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN

(Burkholderia
pseudomallei) 		no annotation 4 GLN A  96
PHE A 196
PRO A 202
LEU A 195
 None
 1.30A 3tgvD-4bqnA:
undetectable		 3tgvD-4bqnA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cv5 PROTEIN CAF40

(Saccharomyces
cerevisiae) 		PF04078
(Rcd1) 		4 TYR B 160
PHE B 208
PRO B 207
LEU B 205
 None
 1.27A 3tgvD-4cv5B:
undetectable		 3tgvD-4cv5B:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4etz PELD

(Pseudomonas
aeruginosa) 		PF13492
(GAF_3)
PF16963
(PelD_GGDEF) 		4 ARG A 168
TYR A 327
PRO A 389
LEU A 164
 None
 1.31A 3tgvD-4etzA:
undetectable		 3tgvD-4etzA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f2a CHOLESTERYL ESTER
TRANSFER PROTEIN

(Homo sapiens) 		PF01273
(LBP_BPI_CETP)
PF02886
(LBP_BPI_CETP_C) 		4 GLN A 111
TYR A  99
PRO A 160
LEU A 154
 None
None
CL  A 609 (-3.6A)
None
 1.40A 3tgvD-4f2aA:
undetectable		 3tgvD-4f2aA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fzh HEMAGGLUTININ-NEURAM
INIDASE

(Avian
avulavirus 1) 		PF00423
(HN) 		4 ARG A 605
GLN A 496
PRO A 450
LEU A 499
 None
 1.18A 3tgvD-4fzhA:
undetectable		 3tgvD-4fzhA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4in9 KARILYSIN PROTEASE

(Tannerella
forsythia) 		PF00413
(Peptidase_M10) 		4 ARG A  68
GLN A  84
TYR A  49
PHE A  71
 None
 1.42A 3tgvD-4in9A:
undetectable		 3tgvD-4in9A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4krp CETUXIMAB LIGHT
CHAIN

(Homo sapiens;
Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 ARG C  39
PHE C  62
PRO C  59
LEU C  47
 None
 1.35A 3tgvD-4krpC:
undetectable		 3tgvD-4krpC:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kxb GLUTAMYL
AMINOPEPTIDASE

(Homo sapiens) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		4 ARG A 628
GLN A 449
TYR A 544
LEU A 562
 None
 1.30A 3tgvD-4kxbA:
undetectable		 3tgvD-4kxbA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o89 RNA 3'-TERMINAL
PHOSPHATE CYCLASE

(Pyrococcus
horikoshii) 		PF01137
(RTC)
PF05189
(RTC_insert) 		4 GLN A 100
PHE A 291
PRO A 290
LEU A 288
 None
 1.05A 3tgvD-4o89A:
undetectable		 3tgvD-4o89A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pfw ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN

(Thermotoga
maritima) 		PF00496
(SBP_bac_5) 		4 TYR A 287
PHE A 360
PRO A 372
LEU A 358
 None
 1.13A 3tgvD-4pfwA:
undetectable		 3tgvD-4pfwA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pfy ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN

(Thermotoga
maritima) 		PF00496
(SBP_bac_5) 		4 TYR A 287
PHE A 360
PRO A 372
LEU A 358
 None
 1.16A 3tgvD-4pfyA:
undetectable		 3tgvD-4pfyA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qq1 TRANSFERRIN-BINDING
PROTEIN 2

(Neisseria
meningitidis) 		PF01298
(TbpB_B_D)
PF17483
(TbpB_C)
PF17484
(TbpB_A) 		4 GLN A 326
TYR A 167
PHE A 299
LEU A 160
 None
 1.40A 3tgvD-4qq1A:
undetectable		 3tgvD-4qq1A:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rs2 PREDICTED
ACYLTRANSFERASE WITH
ACYL-COA
N-ACYLTRANSFERASE
DOMAIN

(Escherichia
coli) 		PF13508
(Acetyltransf_7) 		4 ARG A  35
TYR A  56
PRO A  76
LEU A  34
 None
 1.40A 3tgvD-4rs2A:
undetectable		 3tgvD-4rs2A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4upk PHOSPHONATE
MONOESTER HYDROLASE

(Ruegeria
pomeroyi) 		PF00884
(Sulfatase) 		4 ARG A 399
PHE A 389
PRO A 395
LEU A 386
 None
 1.41A 3tgvD-4upkA:
undetectable		 3tgvD-4upkA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uv6 APICAL MEROZOITE
ANTIGEN 1

(Plasmodium
knowlesi) 		PF02430
(AMA-1) 		4 TYR A  62
PHE A 257
PRO A 361
LEU A 364
 None
 1.40A 3tgvD-4uv6A:
undetectable		 3tgvD-4uv6A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v39 SIALYLTRANSFERASE

(Pasteurella
dagmatis) 		PF11477
(PM0188) 		4 GLN A  46
TYR A  47
PHE A  19
LEU A 217
 None
 1.40A 3tgvD-4v39A:
undetectable		 3tgvD-4v39A:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wb7 DNAJ HOMOLOG
SUBFAMILY B MEMBER
1,CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA

(Homo sapiens) 		PF00069
(Pkinase)
PF00226
(DnaJ) 		4 GLN A 362
PHE A 157
PRO A 156
LEU A 207
 None
 1.24A 3tgvD-4wb7A:
undetectable		 3tgvD-4wb7A:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wqo VON HIPPEL-LINDAU
DISEASE TUMOR
SUPPRESSOR

(Homo sapiens) 		PF01847
(VHL)
PF17211
(VHL_C) 		4 ARG A  82
GLN A 164
TYR A 156
LEU A 128
 None
 1.41A 3tgvD-4wqoA:
undetectable		 3tgvD-4wqoA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wzs ECU04_1440 PROTEIN

(Encephalitozoon
cuniculi) 		PF00352
(TBP) 		4 ARG D 178
TYR D 182
PRO D  23
LEU D  25
 None
 1.41A 3tgvD-4wzsD:
undetectable		 3tgvD-4wzsD:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wzs SIMILARITY TO
HELICASE MOT1

(Encephalitozoon
cuniculi) 		no annotation 4 GLN C 245
TYR C  81
PHE C 198
LEU C 230
 None
 1.35A 3tgvD-4wzsC:
undetectable		 3tgvD-4wzsC:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bsw 4-COUMARATE--COA
LIGASE 2

(Nicotiana
tabacum) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 GLN A  51
TYR A  53
PHE A  92
PRO A  88
 None
 1.16A 3tgvD-5bswA:
undetectable		 3tgvD-5bswA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dds CRMG

(Actinoalloteichus
sp. WH1-2216-6) 		PF00202
(Aminotran_3) 		4 ARG A 194
GLN A 136
PHE A 273
PRO A 274
 None
 1.39A 3tgvD-5ddsA:
undetectable		 3tgvD-5ddsA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae) 		PF12717
(Cnd1) 		4 TYR A 454
PHE A 497
PRO A 450
LEU A 494
 None
 1.22A 3tgvD-5frsA:
undetectable		 3tgvD-5frsA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g39 PHOTOSYSTEM II
MANGANESE-STABILIZIN
G POLYPEPTIDE

(Thermosynechococcus
elongatus) 		PF01716
(MSP) 		4 GLN A  97
PHE A  50
PRO A  47
LEU A  63
 None
 1.25A 3tgvD-5g39A:
undetectable		 3tgvD-5g39A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gy0 GLUCANASE

(Ruminiclostridium
thermocellum) 		PF00759
(Glyco_hydro_9)
PF00942
(CBM_3) 		4 TYR A 411
PHE A 463
PRO A 465
LEU A 460
 None
None
CL  A 705 ( 4.2A)
CL  A 705 (-3.7A)
 1.31A 3tgvD-5gy0A:
undetectable		 3tgvD-5gy0A:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5inr DIPEPTIDASE

(Lactobacillus
farciminis) 		PF03577
(Peptidase_C69) 		4 TYR A 365
PHE A 354
PRO A 362
LEU A 438
 None
 1.19A 3tgvD-5inrA:
undetectable		 3tgvD-5inrA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j5j DESMOCOLLIN-2,DESMOG
LEIN-2

(Homo sapiens) 		PF00028
(Cadherin) 		4 GLN A  70
TYR A  71
PHE A  74
LEU A  50
 None
 1.39A 3tgvD-5j5jA:
undetectable		 3tgvD-5j5jA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kdx METALLOPEPTIDASE

(Pseudomonas
aeruginosa) 		PF13402
(Peptidase_M60) 		4 GLN A 703
PHE A 722
PRO A 723
LEU A 698
 None
EDO  A1008 (-4.7A)
None
None
 1.38A 3tgvD-5kdxA:
undetectable		 3tgvD-5kdxA:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lm8 'MULTICOPPER OXIDASE

(Aspergillus
niger) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ARG A 482
TYR A 291
PHE A 354
PRO A 284
 None
 1.31A 3tgvD-5lm8A:
undetectable		 3tgvD-5lm8A:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mms CYSTATHIONINE
BETA-SYNTHASE

(Homo sapiens) 		PF00291
(PALP) 		4 GLN A 222
TYR A 223
PHE A 310
PRO A  46
 None
 1.34A 3tgvD-5mmsA:
undetectable		 3tgvD-5mmsA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nkz UBIQUITIN-CONJUGATIN
G ENZYME E2-21 KDA

(Ogataea angusta) 		no annotation 4 TYR A 169
PHE A  56
PRO A  55
LEU A 144
 None
 1.37A 3tgvD-5nkzA:
undetectable		 3tgvD-5nkzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nnn CTATC

(Chaetomium
thermophilum) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 GLN A1960
PHE A2086
PRO A2082
LEU A2247
 None
 0.99A 3tgvD-5nnnA:
undetectable		 3tgvD-5nnnA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nqf APICAL MEMBRANE
ANTIGEN 1

(Plasmodium
falciparum) 		PF02430
(AMA-1) 		4 TYR A 117
PHE A 312
PRO A 416
LEU A 419
 TYR  A 117 ( 1.3A)
PHE  A 312 ( 1.3A)
PRO  A 416 ( 1.1A)
LEU  A 419 ( 0.5A)
 1.34A 3tgvD-5nqfA:
undetectable		 3tgvD-5nqfA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ohx CYSTATHIONINE
BETA-SYNTHASE

(Apis mellifera) 		no annotation 4 GLN A 181
TYR A 182
PHE A 268
PRO A   6
 None
 1.39A 3tgvD-5ohxA:
undetectable		 3tgvD-5ohxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tbd FV FRAGMENT (MAB4D1)
HEAVY CHAIN

(Mus musculus) 		no annotation 4 ARG F  44
PHE F  67
PRO F  64
LEU F  52
 None
 1.04A 3tgvD-5tbdF:
undetectable		 3tgvD-5tbdF:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tgt GLUTAMATE--TRNA
LIGASE

(Pseudomonas
aeruginosa) 		PF00749
(tRNA-synt_1c) 		4 GLN A 469
TYR A 465
PHE A 263
PRO A 258
 None
 1.21A 3tgvD-5tgtA:
undetectable		 3tgvD-5tgtA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uz5 56 KDA U1 SMALL
NUCLEAR
RIBONUCLEOPROTEIN
COMPONENT

(Saccharomyces
cerevisiae) 		no annotation 4 GLN G 200
TYR G 162
PHE G 235
PRO G  73
 None
 1.18A 3tgvD-5uz5G:
undetectable		 3tgvD-5uz5G:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wbl REGULATORY-ASSOCIATE
D PROTEIN OF TOR 1

(Arabidopsis
thaliana) 		no annotation 4 TYR A1320
PHE A1038
PRO A1037
LEU A1084
 None
 1.33A 3tgvD-5wblA:
undetectable		 3tgvD-5wblA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xkt UREASE ACCESSORY
PROTEIN UREG

(Klebsiella
pneumoniae) 		no annotation 4 ARG A  63
GLN A  36
PRO A   7
LEU A  91
 None
 1.16A 3tgvD-5xktA:
undetectable		 3tgvD-5xktA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yd5 SCFV 4B08

(Mus musculus) 		no annotation 4 ARG A 184
PHE A 207
PRO A 204
LEU A 192
 None
 1.34A 3tgvD-5yd5A:
undetectable		 3tgvD-5yd5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoj PROTEIN CFT1
MRNA
3'-END-PROCESSING
PROTEIN YTH1

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		no annotation
no annotation 		4 GLN A1210
PHE B  18
PRO A1201
LEU B  19
 None
 1.22A 3tgvD-6eojA:
undetectable		 3tgvD-6eojA:
7.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fhv GLUCOAMYLASE

(Penicillium
oxalicum) 		no annotation 4 ARG A  81
GLN A 158
PRO A 162
LEU A 164
 B3P  A 652 (-4.0A)
None
None
None
 1.35A 3tgvD-6fhvA:
undetectable		 3tgvD-6fhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gh8 -

(-) 		no annotation 4 GLN A 131
TYR A  49
PHE A 124
PRO A  43
 None
 1.23A 3tgvD-6gh8A:
undetectable		 3tgvD-6gh8A:
undetectable