SIMILAR PATTERNS OF AMINO ACIDS FOR 3TGV_B_BEZB160_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aep APOLIPOPHORIN III

(Locusta
migratoria) 		no annotation 4 LEU A  31
GLY A  30
LEU A  29
GLU A  27
 None
 0.93A 3tgvB-1aepA:
undetectable		 3tgvB-1aepA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cmx PROTEIN (UBIQUITIN
YUH1-UBAL)

(Saccharomyces
cerevisiae) 		PF01088
(Peptidase_C12) 		4 LEU A  27
GLY A  26
LEU A 106
GLU A 107
 None
 1.03A 3tgvB-1cmxA:
0.0		 3tgvB-1cmxA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ffw CHEMOTAXIS PROTEIN
CHEA

(Escherichia
coli) 		PF09078
(CheY-binding) 		4 LEU B 182
GLY B 180
LEU B 179
GLU B 178
 None
 1.10A 3tgvB-1ffwB:
undetectable		 3tgvB-1ffwB:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fi8 ECOTIN
ECOTIN

(Escherichia
coli;
Escherichia
coli) 		PF03974
(Ecotin)
PF03974
(Ecotin) 		4 LEU D 101
GLY D 105
LEU C  40
GLU C  39
 None
 1.03A 3tgvB-1fi8D:
undetectable		 3tgvB-1fi8D:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g7r TRANSLATION
INITIATION FACTOR
IF2/EIF5B

(Methanothermobacter
thermautotrophicus) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF11987
(IF-2)
PF14578
(GTP_EFTU_D4) 		4 LEU A 360
GLY A 361
LEU A 363
GLU A 364
 None
 1.12A 3tgvB-1g7rA:
0.0		 3tgvB-1g7rA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ggm GLYCINE--TRNA LIGASE

(Thermus
thermophilus) 		PF00587
(tRNA-synt_2b)
PF03129
(HGTP_anticodon) 		4 LEU A  41
GLY A  38
LEU A  37
GLU A  40
 None
 1.10A 3tgvB-1ggmA:
0.2		 3tgvB-1ggmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gkr NON-ATP DEPENDENT
L-SELECTIVE
HYDANTOINASE

(Paenarthrobacter
aurescens) 		PF01979
(Amidohydro_1) 		4 LEU A 336
GLY A 337
LEU A 338
GLU A 339
 None
 0.93A 3tgvB-1gkrA:
undetectable		 3tgvB-1gkrA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ifg ECOTIN

(Escherichia
coli) 		PF03974
(Ecotin) 		4 LEU A 101
GLY A 105
LEU A  40
GLU A  39
 None
 1.01A 3tgvB-1ifgA:
0.0		 3tgvB-1ifgA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iwp GLYCEROL DEHYDRATASE
ALPHA SUBUNIT

(Klebsiella
pneumoniae) 		PF02286
(Dehydratase_LU) 		4 LEU A 255
GLY A 213
LEU A 210
GLU A 209
 None
 1.03A 3tgvB-1iwpA:
0.0		 3tgvB-1iwpA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j0a 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
DEAMINASE

(Pyrococcus
horikoshii) 		PF00291
(PALP) 		4 LEU A 195
GLY A 213
LEU A 248
GLU A 247
 None
 1.00A 3tgvB-1j0aA:
undetectable		 3tgvB-1j0aA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lmk ANTI-PHOSPHATIDYLINO
SITOL SPECIFIC
PHOSPHOLIPASE C
DIABODY

(Mus musculus) 		PF07686
(V-set) 		4 LEU A 288
GLY A 289
LEU A 309
GLU A 310
 None
 1.12A 3tgvB-1lmkA:
undetectable		 3tgvB-1lmkA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m0w GLUTATHIONE
SYNTHETASE

(Saccharomyces
cerevisiae) 		PF03199
(GSH_synthase)
PF03917
(GSH_synth_ATP) 		4 LEU A 465
GLY A 444
LEU A 443
GLU A 442
 None
None
None
ANP  A 504 (-2.8A)
 0.85A 3tgvB-1m0wA:
undetectable		 3tgvB-1m0wA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n5d CARBONYL
REDUCTASE/20BETA-HYD
ROXYSTEROID
DEHYDROGENASE

(Sus scrofa) 		PF00106
(adh_short) 		4 LEU A 170
GLY A 169
LEU A 167
GLU A 166
 None
 1.13A 3tgvB-1n5dA:
undetectable		 3tgvB-1n5dA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qmh RNA 3'-TERMINAL
PHOSPHATE CYCLASE

(Escherichia
coli) 		PF01137
(RTC)
PF05189
(RTC_insert) 		4 LEU A  48
GLY A  73
LEU A  72
GLU A  71
 None
 0.95A 3tgvB-1qmhA:
undetectable		 3tgvB-1qmhA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ryj UNKNOWN

(Methanothermococcus
thermolithotrophicus) 		PF02597
(ThiS) 		4 LEU A  33
GLY A  34
LEU A  36
GLU A  37
 None
 1.12A 3tgvB-1ryjA:
undetectable		 3tgvB-1ryjA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s70 130 KDA
MYOSIN-BINDING
SUBUNIT OF SMOOTH
MUSCLE MYOSIN
PHOPHATASE (M130)

(Gallus gallus) 		PF12796
(Ank_2) 		4 LEU B 277
GLY B 278
LEU B 280
GLU B 281
 None
 0.88A 3tgvB-1s70B:
undetectable		 3tgvB-1s70B:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1smk MALATE
DEHYDROGENASE,
GLYOXYSOMAL

(Citrullus
lanatus) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 LEU A 286
GLY A 285
LEU A 314
GLU A 320
 None
 1.03A 3tgvB-1smkA:
undetectable		 3tgvB-1smkA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wf8 NEURABIN-I

(Homo sapiens) 		PF00595
(PDZ) 		4 LEU A   8
GLY A  97
LEU A  10
GLU A   9
 None
 0.99A 3tgvB-1wf8A:
undetectable		 3tgvB-1wf8A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wie RIM BINDING PROTEIN
2

(Homo sapiens) 		PF14604
(SH3_9) 		4 LEU A  40
GLY A  62
LEU A  48
GLU A  63
 None
 1.01A 3tgvB-1wieA:
undetectable		 3tgvB-1wieA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ysq HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YIAJ

(Escherichia
coli) 		PF01614
(IclR) 		4 LEU A 155
GLY A 159
LEU A 163
GLU A 160
 None
 1.07A 3tgvB-1ysqA:
undetectable		 3tgvB-1ysqA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zo1 TRANSLATION
INITIATION FACTOR 2

(Escherichia
coli) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF11987
(IF-2) 		4 LEU I 467
GLY I 466
LEU I 454
GLU I 455
 None
 0.96A 3tgvB-1zo1I:
undetectable		 3tgvB-1zo1I:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2adf 82D6A3 IGG

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L  15
GLY L  16
LEU L  78
GLU L  79
 None
 1.02A 3tgvB-2adfL:
undetectable		 3tgvB-2adfL:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2asu HEPATOCYTE GROWTH
FACTOR-LIKE PROTEIN

(Homo sapiens) 		PF00089
(Trypsin) 		4 LEU B 665
GLY B 677
LEU B 675
GLU B 676
 None
 1.08A 3tgvB-2asuB:
3.1		 3tgvB-2asuB:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dc0 PROBABLE AMIDASE

(Thermus
thermophilus) 		PF01425
(Amidase) 		4 LEU A 396
GLY A 426
LEU A 429
GLU A 430
 None
 0.98A 3tgvB-2dc0A:
undetectable		 3tgvB-2dc0A:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dou PROBABLE
N-SUCCINYLDIAMINOPIM
ELATE
AMINOTRANSFERASE

(Thermus
thermophilus) 		PF00155
(Aminotran_1_2) 		4 LEU A 243
GLY A 244
LEU A 249
GLU A  89
 None
 1.11A 3tgvB-2douA:
undetectable		 3tgvB-2douA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hgs PROTEIN (GLUTATHIONE
SYNTHETASE)

(Homo sapiens) 		PF03199
(GSH_synthase)
PF03917
(GSH_synth_ATP) 		4 LEU A 448
GLY A 427
LEU A 426
GLU A 425
 None
None
None
ADP  A 500 (-2.6A)
 0.88A 3tgvB-2hgsA:
undetectable		 3tgvB-2hgsA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jo6 NITRITE REDUCTASE
[NAD(P)H] SMALL
SUBUNIT

(Escherichia
coli) 		PF13806
(Rieske_2) 		4 LEU A  22
GLY A  24
LEU A  23
GLU A  26
 None
 1.07A 3tgvB-2jo6A:
undetectable		 3tgvB-2jo6A:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kg4 GROWTH ARREST AND
DNA-DAMAGE-INDUCIBLE
PROTEIN GADD45 ALPHA

(Homo sapiens) 		PF01248
(Ribosomal_L7Ae) 		4 LEU A 162
GLY A  20
LEU A  23
GLU A  24
 None
 0.88A 3tgvB-2kg4A:
undetectable		 3tgvB-2kg4A:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ltm NFU1 IRON-SULFUR
CLUSTER SCAFFOLD
HOMOLOG,
MITOCHONDRIAL

(Homo sapiens) 		PF08712
(Nfu_N) 		4 LEU A  80
GLY A  60
LEU A  85
GLU A  59
 None
 1.12A 3tgvB-2ltmA:
undetectable		 3tgvB-2ltmA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2n29 PROTEIN VPU

(Human
immunodeficiency
virus 1) 		PF00558
(Vpu) 		4 LEU A  43
GLY A  40
LEU A  39
GLU A  42
 None
 1.09A 3tgvB-2n29A:
undetectable		 3tgvB-2n29A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nms CMRF35-LIKE-MOLECULE
1

(Homo sapiens) 		PF07686
(V-set) 		4 LEU A  31
GLY A  34
LEU A  98
GLU A  32
 None
 1.12A 3tgvB-2nmsA:
undetectable		 3tgvB-2nmsA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p1g PUTATIVE XYLANASE

(Bacteroides
fragilis) 		PF07313
(DUF1460) 		4 LEU A 186
GLY A 185
LEU A 181
GLU A 182
 None
 1.07A 3tgvB-2p1gA:
undetectable		 3tgvB-2p1gA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p5t PEZT

(Streptococcus
pneumoniae) 		PF06414
(Zeta_toxin) 		4 LEU B 152
GLY B 243
LEU B 247
GLU B 244
 None
 1.01A 3tgvB-2p5tB:
undetectable		 3tgvB-2p5tB:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p9r ALPHA-2-MACROGLOBULI
N

(Homo sapiens) 		PF01835
(A2M_N) 		4 LEU A 164
GLY A 163
LEU A 160
GLU A 161
 None
 0.98A 3tgvB-2p9rA:
undetectable		 3tgvB-2p9rA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pka KALLIKREIN A

(Sus scrofa) 		PF00089
(Trypsin) 		4 LEU B 162
GLY B 133
LEU B 132
GLU B 130
 None
 1.06A 3tgvB-2pkaB:
undetectable		 3tgvB-2pkaB:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uzx HEPATOCYTE GROWTH
FACTOR RECEPTOR

(Homo sapiens) 		PF01403
(Sema)
PF01437
(PSI)
PF01833
(TIG) 		4 LEU B 604
GLY B 606
LEU B 605
GLU B 608
 None
 1.01A 3tgvB-2uzxB:
undetectable		 3tgvB-2uzxB:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44

(Saccharomyces
cerevisiae) 		PF00773
(RNB)
PF17215
(Rrp44_S1)
PF17216
(Rrp44_CSD1) 		4 LEU D 307
GLY D 303
LEU D 286
GLU D 287
 None
 1.04A 3tgvB-2vnuD:
undetectable		 3tgvB-2vnuD:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zr2 SERYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00587
(tRNA-synt_2b)
PF02403
(Seryl_tRNA_N) 		4 LEU A 169
GLY A 171
LEU A 166
GLU A 167
 None
None
None
SO4  A2007 ( 4.4A)
 1.12A 3tgvB-2zr2A:
undetectable		 3tgvB-2zr2A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ad9 SARCOSINE OXIDASE
GAMMA SUBUNIT

(Corynebacterium
sp. U-96) 		PF04268
(SoxG) 		4 LEU C 115
GLY C  42
LEU C  88
GLU C  86
 None
 0.97A 3tgvB-3ad9C:
undetectable		 3tgvB-3ad9C:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bgf F26G19 FAB

(Mus musculus) 		no annotation 4 LEU L  15
GLY L  16
LEU L  78
GLU L  79
 None
 1.03A 3tgvB-3bgfL:
undetectable		 3tgvB-3bgfL:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dfh MANDELATE RACEMASE

(Vibrionales
bacterium
SWAT-3) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 260
GLY A 258
LEU A 257
GLU A 233
 None
 1.09A 3tgvB-3dfhA:
undetectable		 3tgvB-3dfhA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ffh HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE

(Listeria
innocua) 		PF00155
(Aminotran_1_2) 		4 LEU A 134
GLY A 138
LEU A 135
GLU A 139
 None
 1.06A 3tgvB-3ffhA:
undetectable		 3tgvB-3ffhA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fru NEONATAL FC RECEPTOR

(Rattus
norvegicus) 		PF00129
(MHC_I)
PF07654
(C1-set) 		4 LEU A 166
GLY A 167
LEU A 169
GLU A 170
 None
 1.12A 3tgvB-3fruA:
undetectable		 3tgvB-3fruA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nqp SUSD SUPERFAMILY
PROTEIN

(Bacteroides
fragilis) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 LEU A 260
GLY A 232
LEU A 236
GLU A 233
 None
 1.01A 3tgvB-3nqpA:
undetectable		 3tgvB-3nqpA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ocj PUTATIVE EXPORTED
PROTEIN

(Bordetella
parapertussis) 		PF13847
(Methyltransf_31) 		4 LEU A  48
GLY A  47
LEU A  84
GLU A  85
 None
 1.06A 3tgvB-3ocjA:
undetectable		 3tgvB-3ocjA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r08 MOUSE ANTI-MOUSE
CD3EPSILON ANTIBODY
2C11 LIGHT CHAIN

(Cricetulus
migratorius) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L  15
GLY L  16
LEU L  78
GLU L  79
 None
 1.02A 3tgvB-3r08L:
undetectable		 3tgvB-3r08L:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rco TUDOR
DOMAIN-CONTAINING
PROTEIN 7

(Homo sapiens) 		PF12872
(OST-HTH) 		4 LEU A  19
GLY A  21
LEU A  23
GLU A  20
 None
 1.11A 3tgvB-3rcoA:
undetectable		 3tgvB-3rcoA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rk6 POLYADENYLATE-BINDIN
G
PROTEIN-INTERACTING
PROTEIN 1

(Homo sapiens) 		PF02854
(MIF4G) 		4 LEU A 244
GLY A 248
LEU A 251
GLU A 252
 None
 0.94A 3tgvB-3rk6A:
undetectable		 3tgvB-3rk6A:
21.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3tgv HEME-BINDING PROTEIN
HUTZ

(Vibrio cholerae) 		PF01243
(Putative_PNPOx) 		4 LEU A  14
GLY A 150
LEU A 151
GLU A 152
 None
 0.26A 3tgvB-3tgvA:
27.3		 3tgvB-3tgvA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tji MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME,
N-TERMINAL DOMAIN
PROTEIN

(Enterobacter
sp. 638) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 258
GLY A 256
LEU A 255
GLU A 231
 None
None
None
MG  A 601 (-2.8A)
 0.98A 3tgvB-3tjiA:
undetectable		 3tgvB-3tjiA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u6n HIGH-CONDUCTANCE
CA2+-ACTIVATED K+
CHANNEL PROTEIN

(Danio rerio) 		PF02254
(TrkA_N)
PF03493
(BK_channel_a) 		4 LEU A 598
GLY A 599
LEU A 541
GLU A 539
 None
 1.04A 3tgvB-3u6nA:
undetectable		 3tgvB-3u6nA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ubl GLUTATHIONE
TRANSFERASE

(Leptospira
interrogans) 		PF13417
(GST_N_3) 		4 LEU A  18
GLY A  19
LEU A  21
GLU A  22
 None
None
None
SO4  A 242 ( 4.0A)
 1.10A 3tgvB-3ublA:
undetectable		 3tgvB-3ublA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3um1 BRO1
DOMAIN-CONTAINING
PROTEIN BROX

(Homo sapiens) 		PF03097
(BRO1) 		4 LEU A 274
GLY A 258
LEU A 262
GLU A 259
 None
 1.02A 3tgvB-3um1A:
undetectable		 3tgvB-3um1A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3umt SCFV HEAVY CHAIN AND
LIGHT CHAIN

(Mus musculus) 		PF07686
(V-set) 		4 LEU A 152
GLY A 153
LEU A 215
GLU A 216
 None
 1.04A 3tgvB-3umtA:
undetectable		 3tgvB-3umtA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE

(Archaeoglobus
fulgidus) 		PF02516
(STT3) 		4 LEU A 127
GLY A 175
LEU A 178
GLU A 130
 None
 1.12A 3tgvB-3wajA:
undetectable		 3tgvB-3wajA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ccl 50S RIBOSOMAL
PROTEIN L16 ARGININE
HYDROXYLASE

(Escherichia
coli) 		PF08007
(Cupin_4) 		4 LEU A  43
GLY A  42
LEU A  40
GLU A  39
 None
 1.06A 3tgvB-4cclA:
undetectable		 3tgvB-4cclA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d9r COMPLEMENT FACTOR D

(Homo sapiens) 		PF00089
(Trypsin) 		4 LEU A 199
GLY A 211
LEU A 209
GLU A 210
 None
 1.09A 3tgvB-4d9rA:
2.8		 3tgvB-4d9rA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e2i LARGE T ANTIGEN

(Macaca mulatta
polyomavirus 1) 		PF06431
(Polyoma_lg_T_C) 		4 LEU A 461
GLY A 462
LEU A 509
GLU A 510
 None
 0.92A 3tgvB-4e2iA:
undetectable		 3tgvB-4e2iA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eba RNA15

(Kluyveromyces
lactis) 		PF14327
(CSTF2_hinge) 		4 LEU G 138
GLY G 136
LEU G 135
GLU G 134
 None
 1.05A 3tgvB-4ebaG:
undetectable		 3tgvB-4ebaG:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eyo EXTRACELLULAR
LIGAND-BINDING
RECEPTOR

(Rhodopseudomonas
palustris) 		PF13458
(Peripla_BP_6) 		4 LEU A 178
GLY A 182
LEU A 187
GLU A 183
 None
 1.09A 3tgvB-4eyoA:
undetectable		 3tgvB-4eyoA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fle ESTERASE

(Yersinia
enterocolitica) 		PF05728
(UPF0227) 		4 LEU A 104
GLY A 105
LEU A 118
GLU A 119
 None
 1.12A 3tgvB-4fleA:
undetectable		 3tgvB-4fleA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g3h ARGINASE (ROCF)

(Helicobacter
pylori) 		PF00491
(Arginase) 		4 LEU A 165
GLY A 166
LEU A 167
GLU A 168
 None
 1.02A 3tgvB-4g3hA:
undetectable		 3tgvB-4g3hA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gdf LARGE T ANTIGEN

(Macaca mulatta
polyomavirus 1) 		PF02217
(T_Ag_DNA_bind)
PF06431
(Polyoma_lg_T_C) 		4 LEU A 461
GLY A 462
LEU A 509
GLU A 510
 None
 1.06A 3tgvB-4gdfA:
undetectable		 3tgvB-4gdfA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ghk GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE

(Burkholderia
thailandensis) 		PF00171
(Aldedh) 		4 LEU A 386
GLY A 404
LEU A 405
GLU A 406
 None
 0.95A 3tgvB-4ghkA:
undetectable		 3tgvB-4ghkA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gis ENOLASE

(Vibrio harveyi) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 258
GLY A 256
LEU A 255
GLU A 231
 None
None
None
MG  A 405 (-2.7A)
 0.94A 3tgvB-4gisA:
undetectable		 3tgvB-4gisA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h5y LIDA PROTEIN,
SUBSTRATE OF THE
DOT/ICM SYSTEM

(Legionella
pneumophila) 		no annotation 4 LEU A 115
GLY A  92
LEU A  93
GLU A  91
 None
 1.10A 3tgvB-4h5yA:
undetectable		 3tgvB-4h5yA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hyz UNCHARACTERIZED
PROTEIN

([Ruminococcus]
gnavus) 		PF13026
(DUF3887) 		4 LEU A 109
GLY A 110
LEU A  42
GLU A  41
 None
 0.89A 3tgvB-4hyzA:
undetectable		 3tgvB-4hyzA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN

(Ruegeria sp.
TM1040) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 121
GLY A  47
LEU A  39
GLU A  46
 None
 1.08A 3tgvB-4ip4A:
undetectable		 3tgvB-4ip4A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iul EUKARYOTIC
TRANSLATION
INITIATION FACTOR 4
GAMMA 2

(Homo sapiens) 		PF02854
(MIF4G) 		4 LEU A 220
GLY A 218
LEU A 217
GLU A 216
 None
 1.10A 3tgvB-4iulA:
undetectable		 3tgvB-4iulA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iuw NEUTRAL
ENDOPEPTIDASE

(Lactobacillus
rhamnosus) 		PF01431
(Peptidase_M13)
PF05649
(Peptidase_M13_N) 		4 LEU A 282
GLY A  81
LEU A  80
GLU A  83
 None
 1.00A 3tgvB-4iuwA:
undetectable		 3tgvB-4iuwA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jhj MIF4G
DOMAIN-CONTAINING
PROTEIN B

(Danio rerio) 		PF02854
(MIF4G) 		4 LEU A 155
GLY A 159
LEU A 162
GLU A 163
 None
 0.86A 3tgvB-4jhjA:
undetectable		 3tgvB-4jhjA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k2u ANTIBODY LIGHT CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L  15
GLY L  16
LEU L  78
GLU L  79
 None
 0.88A 3tgvB-4k2uL:
undetectable		 3tgvB-4k2uL:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p72 PHENYLALANINE--TRNA
LIGASE BETA SUBUNIT

(Pseudomonas
aeruginosa) 		PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5) 		4 LEU A 288
GLY A 318
LEU A 289
GLU A 319
 None
 1.09A 3tgvB-4p72A:
undetectable		 3tgvB-4p72A:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4peq RIBONUCLEASE/ANGIOGE
NIN INHIBITOR 1

(Bos taurus) 		PF13516
(LRR_6) 		4 LEU B 348
GLY B 349
LEU B 377
GLU B 376
 None
 1.11A 3tgvB-4peqB:
undetectable		 3tgvB-4peqB:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4per RIBONUCLEASE
INHIBITOR

(Gallus gallus) 		PF13516
(LRR_6) 		4 LEU A 120
GLY A 121
LEU A 149
GLU A 148
 None
 1.03A 3tgvB-4perA:
undetectable		 3tgvB-4perA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pp1 LIGHT CHAIN OF FAB
FRAGMENT OF MAB 5H8

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU C  15
GLY C  16
LEU C  78
GLU C  79
 None
 1.03A 3tgvB-4pp1C:
undetectable		 3tgvB-4pp1C:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tmk PROTEIN (THYMIDYLATE
KINASE)

(Escherichia
coli) 		PF02223
(Thymidylate_kin) 		4 LEU A 147
GLY A 146
LEU A  11
GLU A  12
 None
None
None
T5A  A 214 (-3.7A)
 1.04A 3tgvB-4tmkA:
undetectable		 3tgvB-4tmkA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w5j ADENYLATE KINASE

(Streptococcus
pneumoniae) 		PF00406
(ADK) 		4 LEU A   3
GLY A 110
LEU A 108
GLU A 109
 None
 1.03A 3tgvB-4w5jA:
undetectable		 3tgvB-4w5jA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B
GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT C

(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa) 		PF02637
(GatB_Yqey)
PF02934
(GatB_N)
PF02686
(Glu-tRNAGln) 		4 LEU C  87
GLY B 141
LEU B 132
GLU B 134
 None
 1.08A 3tgvB-4wj3C:
undetectable		 3tgvB-4wj3C:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xmp LIGHT CHAIN OF
ANTIBODY VRC08

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L  15
GLY L  16
LEU L  78
GLU L  79
 None
 0.93A 3tgvB-4xmpL:
undetectable		 3tgvB-4xmpL:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y61 SLIT AND NTRK-LIKE
PROTEIN 2

(Mus musculus) 		PF13855
(LRR_8) 		4 LEU B 131
GLY B 132
LEU B 133
GLU B 134
 None
 1.10A 3tgvB-4y61B:
undetectable		 3tgvB-4y61B:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cj5 ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE

(Mycolicibacterium
thermoresistibile) 		PF00128
(Alpha-amylase)
PF11896
(DUF3416) 		4 LEU A 178
GLY A 152
LEU A 156
GLU A 157
 None
 1.08A 3tgvB-5cj5A:
undetectable		 3tgvB-5cj5A:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f4y PROTEIN SHROOM2

(Homo sapiens) 		PF08687
(ASD2) 		4 LEU A1447
GLY A1598
LEU A1602
GLU A1599
 None
 0.88A 3tgvB-5f4yA:
undetectable		 3tgvB-5f4yA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fqd DNA DAMAGE-BINDING
PROTEIN 1

(Homo sapiens) 		PF03178
(CPSF_A)
PF10433
(MMS1_N) 		4 LEU A 304
GLY A 306
LEU A 280
GLU A 307
 None
 1.10A 3tgvB-5fqdA:
undetectable		 3tgvB-5fqdA:
11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gru DIABODY PROTEIN

(Homo sapiens) 		PF07686
(V-set) 		4 LEU H 149
GLY H 150
LEU H 212
GLU H 213
 LEU  H 149 ( 0.6A)
GLY  H 150 ( 0.0A)
LEU  H 212 ( 0.6A)
GLU  H 213 ( 0.6A)
 0.95A 3tgvB-5gruH:
undetectable		 3tgvB-5gruH:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j47 LARGE T ANTIGEN

(Human
polyomavirus 2) 		PF06431
(Polyoma_lg_T_C) 		4 LEU A 462
GLY A 463
LEU A 510
GLU A 511
 None
 1.04A 3tgvB-5j47A:
undetectable		 3tgvB-5j47A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jyl SCFV TSP7

(Mus musculus) 		PF07686
(V-set) 		4 LEU B 153
GLY B 154
LEU B 216
GLU B 217
 None
 0.95A 3tgvB-5jylB:
undetectable		 3tgvB-5jylB:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kov PL-2 SCFV CHAIN

(Mus musculus) 		PF07686
(V-set) 		4 LEU C1015
GLY C1016
LEU C1078
GLU C1079
 None
 1.08A 3tgvB-5kovC:
undetectable		 3tgvB-5kovC:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lf9 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 22

(Homo sapiens) 		no annotation 4 LEU A 207
GLY A 209
LEU A 208
GLU A 223
 None
 1.00A 3tgvB-5lf9A:
undetectable		 3tgvB-5lf9A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lsp HEPATOCYTE GROWTH
FACTOR RECEPTOR

(Homo sapiens) 		PF01437
(PSI)
PF01833
(TIG) 		4 LEU A 604
GLY A 606
LEU A 605
GLU A 608
 None
 0.92A 3tgvB-5lspA:
undetectable		 3tgvB-5lspA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ncc FATTY ACID
PHOTODECARBOXYLASE

(Chlorella
variabilis) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 LEU A 313
GLY A 314
LEU A 331
GLU A 330
 None
 1.09A 3tgvB-5nccA:
undetectable		 3tgvB-5nccA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oes GLUTATHIONE
SYNTHETASE

(Solanum
tuberosum) 		no annotation 4 LEU A 457
GLY A 436
LEU A 435
GLU A 434
 None
None
None
ADP  A 501 ( 2.7A)
 0.87A 3tgvB-5oesA:
undetectable		 3tgvB-5oesA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t5i TUNGSTEN
FORMYLMETHANOFURAN
DEHYDROGENASE
SUBUNIT FWDG

(Methanothermobacter
wolfeii) 		PF12838
(Fer4_7) 		4 LEU G   5
GLY G   4
LEU G  78
GLU G  79
 SF4  G 102 ( 4.6A)
None
None
None
 1.09A 3tgvB-5t5iG:
undetectable		 3tgvB-5t5iG:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tjr METHYLMALONATE-SEMIA
LDEHYDE
DEHYDROGENASE

(Pseudomonas sp.
AAC) 		PF00171
(Aldedh) 		4 LEU A 156
GLY A 104
LEU A 101
GLU A 100
 None
 1.10A 3tgvB-5tjrA:
undetectable		 3tgvB-5tjrA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v76 MICROCOMPARTMENTS
PROTEIN

(Haliangium
ochraceum) 		no annotation 4 LEU A 164
GLY A 129
LEU A 165
GLU A 166
 None
 1.05A 3tgvB-5v76A:
undetectable		 3tgvB-5v76A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wro ENOLASE

(Drosophila
melanogaster) 		PF00113
(Enolase_C)
PF03952
(Enolase_N) 		4 LEU A 144
GLY A 141
LEU A 140
GLU A 143
 None
 1.06A 3tgvB-5wroA:
undetectable		 3tgvB-5wroA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xqw FAB FRAGMENT OF
CATALYTIC ANTIBODY
7B9, LIGHT CHAIN

(Mus musculus) 		no annotation 4 LEU L  15
GLY L  16
LEU L  78
GLU L  79
 None
 0.93A 3tgvB-5xqwL:
undetectable		 3tgvB-5xqwL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3r DNA-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
PF02260
(FATC)
PF08163
(NUC194) 		4 LEU C1484
GLY C1480
LEU C1483
GLU C1482
 None
 1.10A 3tgvB-5y3rC:
undetectable		 3tgvB-5y3rC:
3.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bb4 MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
LIGHT CHAIN

(Mus musculus) 		no annotation 4 LEU L  15
GLY L  16
LEU L  78
GLU L  79
 None
 1.05A 3tgvB-6bb4L:
undetectable		 3tgvB-6bb4L:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fd2 PUTATIVE APRAMYCIN
BIOSYNTHETIC
OXIDOREDUCTASE 4

(Streptoalloteichus
tenebrarius) 		no annotation 4 LEU B 369
GLY B 368
LEU B 365
GLU B 366
 None
 0.98A 3tgvB-6fd2B:
undetectable		 3tgvB-6fd2B:
undetectable