SIMILAR PATTERNS OF AMINO ACIDS FOR 3T3S_C_9PLC1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bhd UTROPHIN

(Homo sapiens) 		PF00307
(CH) 		4 PHE A 215
ASN A 186
ALA A 184
LEU A 247
 None
 0.97A 3t3sC-1bhdA:
undetectable		 3t3sC-1bhdA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ej6 LAMBDA1

(Reovirus sp.) 		no annotation 4 PHE B 977
ALA B 927
THR B 930
LEU B 363
 None
 1.06A 3t3sC-1ej6B:
0.0		 3t3sC-1ej6B:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1evq SERINE HYDROLASE

(Alicyclobacillus
acidocaldarius) 		PF07859
(Abhydrolase_3) 		4 PHE A 214
PHE A  30
ALA A  27
LEU A 115
 EPE  A 455 (-4.8A)
None
None
None
 1.11A 3t3sC-1evqA:
0.0		 3t3sC-1evqA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gpe PROTEIN (GLUCOSE
OXIDASE)

(Penicillium
amagasakiense) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 PHE A 414
PHE A 362
ALA A 366
LEU A 408
 None
 0.90A 3t3sC-1gpeA:
0.0		 3t3sC-1gpeA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m1c MAJOR COAT PROTEIN

(Saccharomyces
cerevisiae
virus L-A) 		PF09220
(LA-virus_coat) 		4 PHE A 362
PHE A  26
ALA A 600
LEU A 136
 None
 1.11A 3t3sC-1m1cA:
undetectable		 3t3sC-1m1cA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mpp PEPSIN

(Rhizomucor
pusillus) 		PF00026
(Asp) 		4 PHE A 206
PHE A 227
PHE A 299
LEU A 260
 None
 1.06A 3t3sC-1mppA:
0.0		 3t3sC-1mppA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1npc NEUTRAL PROTEASE

(Bacillus cereus) 		PF01447
(Peptidase_M4)
PF02868
(Peptidase_M4_C) 		4 PHE A 282
ALA A 285
THR A 280
LEU A 156
 None
 1.05A 3t3sC-1npcA:
0.0		 3t3sC-1npcA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1odv PHOTOACTIVE YELLOW
PROTEIN

(Halorhodospira
halophila) 		PF00989
(PAS) 		4 PHE A  63
PHE A  75
THR A  90
LEU A  88
 None
 0.97A 3t3sC-1odvA:
undetectable		 3t3sC-1odvA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP3)

(Foot-and-mouth
disease virus) 		PF00073
(Rhv) 		4 PHE 3 209
ASN 3 106
ALA 3 203
THR 3  89
 None
 1.11A 3t3sC-1qgc3:
undetectable		 3t3sC-1qgc3:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s9i DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 2

(Homo sapiens) 		PF00069
(Pkinase) 		4 PHE A 137
PHE A  72
THR A  87
LEU A 102
 None
 0.96A 3t3sC-1s9iA:
0.0		 3t3sC-1s9iA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t3i PROBABLE CYSTEINE
DESULFURASE

(Synechocystis
sp.) 		PF00266
(Aminotran_5) 		4 PHE A  17
ASN A 394
PHE A 392
ALA A  10
 None
 1.05A 3t3sC-1t3iA:
undetectable		 3t3sC-1t3iA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uyv ACETYL-COA
CARBOXYLASE

(Saccharomyces
cerevisiae) 		PF01039
(Carboxyl_trans) 		4 PHE A1596
PHE A1604
ALA A1712
THR A1715
 None
 1.01A 3t3sC-1uyvA:
undetectable		 3t3sC-1uyvA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vcj NEURAMINIDASE

(Influenza B
virus) 		PF00064
(Neur) 		4 PHE A 352
PHE A 302
THR A 319
LEU A 394
 None
 1.09A 3t3sC-1vcjA:
undetectable		 3t3sC-1vcjA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1whj RIKEN CDNA
1700024K14

(Mus musculus) 		PF01302
(CAP_GLY) 		4 PHE A  76
PHE A  85
ALA A  86
LEU A  59
 None
 1.09A 3t3sC-1whjA:
undetectable		 3t3sC-1whjA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x8v CYTOCHROME P450 51

(Mycobacterium
tuberculosis) 		PF00067
(p450) 		4 PHE A 255
ALA A 256
THR A 260
LEU A 321
 None
ESL  A 471 ( 3.4A)
HEM  A 470 (-3.6A)
HEM  A 470 (-4.1A)
 0.61A 3t3sC-1x8vA:
31.8		 3t3sC-1x8vA:
25.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yfm FUMARASE

(Saccharomyces
cerevisiae) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		4 PHE A 169
PHE A  74
ALA A  73
LEU A 395
 None
 0.95A 3t3sC-1yfmA:
0.1		 3t3sC-1yfmA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c4m GLYCOGEN
PHOSPHORYLASE

(Corynebacterium
callunae) 		PF00343
(Phosphorylase) 		4 ASN A 285
ALA A 287
THR A 328
LEU A 306
 None
 0.93A 3t3sC-2c4mA:
undetectable		 3t3sC-2c4mA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c8s CYTOCHROME C-L

(Methylobacterium
extorquens) 		PF13442
(Cytochrome_CBB3) 		4 PHE A  98
ASN A  45
ALA A  35
THR A  33
 None
 0.93A 3t3sC-2c8sA:
undetectable		 3t3sC-2c8sA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c9k PESTICIDAL CRYSTAL
PROTEIN CRY4AA

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		4 PHE A 635
ASN A 629
THR A 562
LEU A 566
 None
 0.91A 3t3sC-2c9kA:
1.6		 3t3sC-2c9kA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2coz CENTROSOME-ASSOCIATE
D PROTEIN 350

(Homo sapiens) 		PF01302
(CAP_GLY) 		4 PHE A  83
PHE A  92
ALA A  93
LEU A  66
 None
 0.94A 3t3sC-2cozA:
undetectable		 3t3sC-2cozA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2guz MITOCHONDRIAL IMPORT
INNER MEMBRANE
TRANSLOCASE SUBUNIT
TIM14
MITOCHONDRIAL IMPORT
INNER MEMBRANE
TRANSLOCASE SUBUNIT
TIM16

(Saccharomyces
cerevisiae) 		PF03656
(Pam16)
no annotation 		4 PHE A 104
ASN A 155
ALA A 157
LEU B  97
 None
 1.11A 3t3sC-2guzA:
undetectable		 3t3sC-2guzA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hcb CHROMOSOMAL
REPLICATION
INITIATOR PROTEIN
DNAA

(Aquifex
aeolicus) 		PF00308
(Bac_DnaA)
PF08299
(Bac_DnaA_C) 		4 PHE A 195
PHE A 151
ALA A 148
LEU A 211
 None
 1.09A 3t3sC-2hcbA:
undetectable		 3t3sC-2hcbA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i15 HYPOTHETICAL PROTEIN
MG296 HOMOLOG

(Mycoplasma
pneumoniae) 		PF09644
(Mg296) 		4 PHE A 100
PHE A  62
ALA A  61
LEU A  54
 None
 1.00A 3t3sC-2i15A:
undetectable		 3t3sC-2i15A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2obi PHOSPHOLIPID
HYDROPEROXIDE
GLUTATHIONE
PEROXIDASE (GPX4)

(Homo sapiens) 		PF00255
(GSHPx) 		4 PHE A  92
ASN A  76
ALA A  43
THR A  49
 None
 0.82A 3t3sC-2obiA:
undetectable		 3t3sC-2obiA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oor NAD(P)
TRANSHYDROGENASE
SUBUNIT BETA

(Rhodospirillum
rubrum) 		PF02233
(PNTB) 		4 PHE C  41
ASN C  45
THR C 159
LEU C 161
 None
 1.03A 3t3sC-2oorC:
undetectable		 3t3sC-2oorC:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z0w CAP-GLY
DOMAIN-CONTAINING
LINKER PROTEIN 4

(Homo sapiens) 		PF01302
(CAP_GLY) 		4 PHE A  62
PHE A  71
ALA A  72
LEU A  45
 None
 1.09A 3t3sC-2z0wA:
undetectable		 3t3sC-2z0wA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zyj ALPHA-AMINODIPATE
AMINOTRANSFERASE

(Thermus
thermophilus) 		PF00155
(Aminotran_1_2) 		4 PHE A 341
PHE A 351
ALA A  38
LEU A  28
 None
 1.05A 3t3sC-2zyjA:
undetectable		 3t3sC-2zyjA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a1b DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3A,
HISTONE H3.1

(Homo sapiens) 		no annotation 4 PHE A 609
PHE A 521
THR A 538
LEU A 508
 None
EDO  A 615 ( 3.9A)
EDO  A 615 ( 4.3A)
None
 0.72A 3t3sC-3a1bA:
undetectable		 3t3sC-3a1bA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dfr DIHYDROFOLATE
REDUCTASE

(Lactobacillus
casei) 		PF00186
(DHFR_1) 		4 PHE A 106
PHE A  83
ALA A  80
LEU A  62
 None
None
None
NDP  A 163 ( 3.9A)
 1.00A 3t3sC-3dfrA:
undetectable		 3t3sC-3dfrA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ewb 2-ISOPROPYLMALATE
SYNTHASE

(Listeria
monocytogenes) 		PF00682
(HMGL-like) 		4 PHE X 265
ASN X 229
ALA X 239
THR X 210
 None
 0.88A 3t3sC-3ewbX:
undetectable		 3t3sC-3ewbX:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fle SE_1780 PROTEIN

(Staphylococcus
epidermidis) 		PF06028
(DUF915) 		4 ASN A 147
PHE A 150
ALA A 151
LEU A 250
 None
 0.86A 3t3sC-3fleA:
undetectable		 3t3sC-3fleA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g3z TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY

(Neisseria
meningitidis) 		PF01047
(MarR) 		4 PHE A  18
PHE A  32
ALA A  33
THR A  37
 None
 0.86A 3t3sC-3g3zA:
undetectable		 3t3sC-3g3zA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0o BETA-GLUCANASE

(Fibrobacter
succinogenes) 		PF00722
(Glyco_hydro_16) 		4 PHE A 152
ALA A  32
THR A  35
LEU A 228
 None
 0.98A 3t3sC-3h0oA:
undetectable		 3t3sC-3h0oA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hbz PUTATIVE GLYCOSIDE
HYDROLASE

(Bacteroides
thetaiotaomicron) 		PF13201
(PCMD) 		4 PHE A 307
ASN A 326
ALA A 328
LEU A 355
 None
 1.11A 3t3sC-3hbzA:
undetectable		 3t3sC-3hbzA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE

(Bacteroides
thetaiotaomicron) 		PF00809
(Pterin_bind) 		4 ASN A 561
PHE A 564
ALA A 524
THR A 527
 THH  A 642 ( 3.3A)
None
None
None
 0.93A 3t3sC-3k13A:
undetectable		 3t3sC-3k13A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kij PROBABLE GLUTATHIONE
PEROXIDASE 8

(Homo sapiens) 		PF00255
(GSHPx) 		4 PHE A 125
ASN A 109
ALA A  76
THR A  82
 None
 0.88A 3t3sC-3kijA:
undetectable		 3t3sC-3kijA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kt4 PKHD-TYPE
HYDROXYLASE TPA1

(Saccharomyces
cerevisiae) 		PF10637
(Ofd1_CTDD)
PF13661
(2OG-FeII_Oxy_4) 		4 PHE A 483
ALA A 488
THR A 491
LEU A 534
 None
 0.98A 3t3sC-3kt4A:
undetectable		 3t3sC-3kt4A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kvn ESTERASE ESTA

(Pseudomonas
aeruginosa) 		no annotation 4 PHE X 350
ALA X 394
THR X 377
LEU X 330
 None
 1.04A 3t3sC-3kvnX:
undetectable		 3t3sC-3kvnX:
22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pdi NITROGENASE MOFE
COFACTOR
BIOSYNTHESIS PROTEIN
NIFN

(Azotobacter
vinelandii) 		PF00148
(Oxidored_nitro) 		4 PHE B 142
PHE B  51
ALA B  48
LEU B  29
 None
 1.00A 3t3sC-3pdiB:
undetectable		 3t3sC-3pdiB:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pgx CARVEOL
DEHYDROGENASE

(Mycobacterium
avium) 		PF13561
(adh_short_C2) 		4 PHE A  15
ALA A 107
THR A  17
LEU A  88
 None
 0.93A 3t3sC-3pgxA:
undetectable		 3t3sC-3pgxA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q9t CHOLINE
DEHYDROGENASE AND
RELATED
FLAVOPROTEINS

(Aspergillus
oryzae) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 PHE A 170
PHE A 480
ALA A 177
LEU A 197
 None
 1.11A 3t3sC-3q9tA:
undetectable		 3t3sC-3q9tA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3quf EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1

(Bifidobacterium
longum) 		PF13416
(SBP_bac_8) 		4 PHE A 172
PHE A 150
ALA A 291
LEU A 157
 None
 0.95A 3t3sC-3qufA:
undetectable		 3t3sC-3qufA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qwb PROBABLE QUINONE
OXIDOREDUCTASE

(Saccharomyces
cerevisiae) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 PHE A 222
ALA A 136
THR A 140
LEU A 169
 None
 1.06A 3t3sC-3qwbA:
undetectable		 3t3sC-3qwbA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r38 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1

(Listeria
monocytogenes) 		PF00275
(EPSP_synthase) 		4 PHE A 198
ALA A  30
THR A  32
LEU A  42
 None
 0.93A 3t3sC-3r38A:
undetectable		 3t3sC-3r38A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rd8 FUMARATE HYDRATASE
CLASS II

(Mycolicibacterium
smegmatis) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		4 PHE A 141
ALA A  51
THR A  47
LEU A 368
 None
 0.88A 3t3sC-3rd8A:
0.6		 3t3sC-3rd8A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE

(Sus scrofa) 		PF00305
(Lipoxygenase) 		4 PHE A 175
ASN A 401
ALA A 404
LEU A 597
 OYP  A 664 (-4.1A)
None
OYP  A 664 (-3.3A)
OYP  A 664 ( 4.9A)
 0.90A 3t3sC-3rdeA:
undetectable		 3t3sC-3rdeA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rhg PUTATIVE
PHOPHOTRIESTERASE

(Proteus
mirabilis) 		PF02126
(PTE) 		4 PHE A  27
ALA A 112
THR A 115
LEU A  81
 None
 0.90A 3t3sC-3rhgA:
undetectable		 3t3sC-3rhgA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3slt SERINE PROTEASE ESPP

(Escherichia
coli) 		PF03797
(Autotransporter) 		4 PHE A1136
ALA A1008
THR A1239
LEU A1241
 None
 0.91A 3t3sC-3sltA:
undetectable		 3t3sC-3sltA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sx2 PUTATIVE
3-KETOACYL-(ACYL-CAR
RIER-PROTEIN)
REDUCTASE

(Mycobacterium
avium) 		PF13561
(adh_short_C2) 		4 PHE A  15
ALA A 106
THR A  17
LEU A  87
 None
 0.67A 3t3sC-3sx2A:
undetectable		 3t3sC-3sx2A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tsc PUTATIVE
OXIDOREDUCTASE

(Mycobacterium
avium) 		PF13561
(adh_short_C2) 		4 PHE A  11
ALA A 103
THR A  13
LEU A  84
 None
 0.83A 3t3sC-3tscA:
undetectable		 3t3sC-3tscA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uve CARVEOL
DEHYDROGENASE
((+)-TRANS-CARVEOL
DEHYDROGENASE)

(Mycobacterium
avium) 		PF13561
(adh_short_C2) 		4 PHE A  11
ALA A 106
THR A  13
LEU A  87
 None
 0.84A 3t3sC-3uveA:
undetectable		 3t3sC-3uveA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zef PRE-MRNA-SPLICING
FACTOR 8

(Saccharomyces
cerevisiae) 		PF08084
(PROCT)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV) 		4 PHE B2329
ASN B2318
ALA B2275
LEU B2307
 None
 1.05A 3t3sC-3zefB:
undetectable		 3t3sC-3zefB:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4awm POLYMERASE PA

(Influenza A
virus) 		PF00603
(Flu_PA) 		4 PHE A   9
ASN A  33
ALA A  37
THR A  40
 None
None
KDH  A 911 (-3.3A)
None
 0.93A 3t3sC-4awmA:
undetectable		 3t3sC-4awmA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bgd PRE-MRNA-SPLICING
FACTOR 8

(Saccharomyces
cerevisiae) 		PF08084
(PROCT) 		4 PHE C2329
ASN C2318
ALA C2275
LEU C2307
 None
 0.95A 3t3sC-4bgdC:
undetectable		 3t3sC-4bgdC:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bnd ALPHA-PHOSPHOGLUCOMU
TASE

(Lactococcus
lactis) 		PF03332
(PMM) 		4 PHE B  87
PHE B  68
ALA B  77
LEU B 200
 None
 0.85A 3t3sC-4bndB:
undetectable		 3t3sC-4bndB:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bug ANCILLARY PROTEIN 1

(Streptococcus
pyogenes) 		PF08341
(TED) 		4 PHE A 327
ASN A 349
ALA A 310
LEU A 345
 None
 1.08A 3t3sC-4bugA:
undetectable		 3t3sC-4bugA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cpn NEURAMINIDASE

(Influenza B
virus) 		PF00064
(Neur) 		4 PHE A 351
PHE A 301
THR A 318
LEU A 393
 None
 1.05A 3t3sC-4cpnA:
undetectable		 3t3sC-4cpnA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4djn RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT M2 B

(Homo sapiens) 		PF00268
(Ribonuc_red_sm) 		4 PHE A  96
PHE A 202
ALA A 203
LEU A 266
 None
 1.10A 3t3sC-4djnA:
undetectable		 3t3sC-4djnA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dvy CYTOTOXICITY-ASSOCIA
TED IMMUNODOMINANT
ANTIGEN

(Helicobacter
pylori) 		no annotation 4 ASN P 595
PHE P 596
ALA P 593
LEU P 623
 None
 1.06A 3t3sC-4dvyP:
0.0		 3t3sC-4dvyP:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dyj BROAD SPECIFICITY
AMINO ACID RACEMASE

(Pseudomonas
putida) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		4 PHE A 267
ALA A 265
THR A 262
LEU A  70
 None
 0.82A 3t3sC-4dyjA:
undetectable		 3t3sC-4dyjA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eay MANNONATE
DEHYDRATASE

(Escherichia
coli) 		PF03786
(UxuA) 		4 ASN A 211
PHE A 212
ALA A 213
THR A 260
 None
 0.96A 3t3sC-4eayA:
undetectable		 3t3sC-4eayA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fwg TTC1975 PEPTIDASE

(Meiothermus
taiwanensis) 		PF05362
(Lon_C)
PF13654
(AAA_32) 		4 PHE A 278
PHE A 326
ALA A 272
LEU A 310
 None
 1.08A 3t3sC-4fwgA:
undetectable		 3t3sC-4fwgA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fwv TTC1975 PEPTIDASE

(Meiothermus
taiwanensis) 		PF13654
(AAA_32) 		4 PHE A 278
PHE A 326
ALA A 272
LEU A 310
 None
 0.99A 3t3sC-4fwvA:
undetectable		 3t3sC-4fwvA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g3j STEROL
14-ALPHA-DEMETHYLASE

(Trypanosoma
brucei) 		PF00067
(p450) 		4 PHE A 290
ALA A 291
THR A 295
LEU A 356
 VNT  A 502 (-4.4A)
HEM  A 501 ( 3.5A)
VNT  A 502 ( 3.2A)
VNT  A 502 ( 4.5A)
 0.51A 3t3sC-4g3jA:
31.2		 3t3sC-4g3jA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g76 PHOSPHODIESTERASE

(Pseudomonas
aeruginosa) 		PF14859
(Colicin_M) 		4 PHE A  85
PHE A 269
ALA A 149
THR A 153
 None
 1.12A 3t3sC-4g76A:
undetectable		 3t3sC-4g76A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gr6 ATRBCX2

(Arabidopsis
thaliana) 		PF02341
(RcbX) 		4 PHE A  46
ALA A  27
THR A  24
LEU A  62
 None
 1.11A 3t3sC-4gr6A:
2.1		 3t3sC-4gr6A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hpf POTASSIUM CHANNEL
SUBFAMILY U MEMBER 1

(Homo sapiens) 		PF03493
(BK_channel_a) 		4 PHE A 517
PHE A 895
ALA A 894
THR A 899
 None
 1.09A 3t3sC-4hpfA:
undetectable		 3t3sC-4hpfA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j4b PYLD

(Methanosarcina
barkeri) 		no annotation 4 ASN A 208
ALA A 229
THR A 223
LEU A 242
 None
NA  A 902 ( 4.1A)
None
None
 0.97A 3t3sC-4j4bA:
undetectable		 3t3sC-4j4bA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jrf PUTATIVE CELL
ADHESION PROTEIN

(Bacteroides
ovatus) 		PF15495
(Fimbrillin_C) 		4 PHE A 277
ASN A 283
PHE A 282
THR A 487
 None
None
None
PG4  A 614 (-3.6A)
 0.97A 3t3sC-4jrfA:
undetectable		 3t3sC-4jrfA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mch URIDINE
PHOSPHORYLASE

(Aliivibrio
fischeri) 		PF01048
(PNP_UDP_1) 		4 ASN A 201
ALA A 231
THR A 234
LEU A 140
 None
 0.87A 3t3sC-4mchA:
undetectable		 3t3sC-4mchA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nfz POLYMERASE PA

(Influenza A
virus) 		PF00603
(Flu_PA) 		4 PHE A   9
ASN A  33
ALA A  37
THR A  40
 None
 1.04A 3t3sC-4nfzA:
undetectable		 3t3sC-4nfzA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qbr DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3A

(Homo sapiens) 		no annotation 4 PHE A 609
PHE A 521
THR A 538
LEU A 508
 None
 0.94A 3t3sC-4qbrA:
undetectable		 3t3sC-4qbrA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rgb CARVEOL
DEHYDROGENASE

(Mycobacterium
avium) 		PF13561
(adh_short_C2) 		4 PHE A  24
ALA A 115
THR A  26
LEU A  96
 None
 0.85A 3t3sC-4rgbA:
undetectable		 3t3sC-4rgbA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rku PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2

(Pisum sativum) 		PF00223
(PsaA_PsaB) 		4 PHE B 244
PHE B 360
THR B 126
LEU B 270
 None
None
CLA  B1215 ( 4.7A)
None
 1.02A 3t3sC-4rkuB:
1.9		 3t3sC-4rkuB:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rph UDP-GALACTOPYRANOSE
MUTASE

(Mycobacterium
tuberculosis) 		no annotation 4 ASN B 140
ALA B 175
THR B 179
LEU B 148
 None
 0.97A 3t3sC-4rphB:
undetectable		 3t3sC-4rphB:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tvs TORSIN-1A-INTERACTIN
G PROTEIN 1

(Homo sapiens) 		PF05609
(LAP1C) 		4 PHE A 481
ALA A 486
THR A 489
LEU A 560
 None
 1.08A 3t3sC-4tvsA:
undetectable		 3t3sC-4tvsA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u8u LINKER L3

(Glossoscolex
paulistus) 		PF00057
(Ldl_recept_a)
PF16915
(Eryth_link_C) 		4 PHE O  99
PHE O 197
PHE O 105
LEU O 185
 None
 1.01A 3t3sC-4u8uO:
undetectable		 3t3sC-4u8uO:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xj6 VC0179-LIKE PROTEIN

(Escherichia
coli) 		no annotation 4 PHE A 100
PHE A  45
THR A 158
LEU A  85
 None
 1.08A 3t3sC-4xj6A:
undetectable		 3t3sC-4xj6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5csl ACETYL-COA
CARBOXYLASE

(Saccharomyces
cerevisiae) 		PF00289
(Biotin_carb_N)
PF00364
(Biotin_lipoyl)
PF01039
(Carboxyl_trans)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2)
PF08326
(ACC_central) 		4 PHE A1596
PHE A1604
ALA A1712
THR A1715
 None
 1.07A 3t3sC-5cslA:
undetectable		 3t3sC-5cslA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5enf PH-INTERACTING
PROTEIN

(Homo sapiens) 		PF00439
(Bromodomain) 		4 PHE A1363
PHE A1414
PHE A1389
LEU A1381
 None
 1.09A 3t3sC-5enfA:
undetectable		 3t3sC-5enfA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h9m E3 UBIQUITIN-PROTEIN
LIGASE SIAH2

(Homo sapiens) 		PF03145
(Sina) 		4 PHE A 229
PHE A 225
PHE A 261
ALA A 262
 None
 1.11A 3t3sC-5h9mA:
undetectable		 3t3sC-5h9mA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i6g ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN,ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum) 		PF01039
(Carboxyl_trans)
PF08326
(ACC_central) 		4 PHE A1641
PHE A1649
ALA A1752
THR A1755
 None
 0.95A 3t3sC-5i6gA:
undetectable		 3t3sC-5i6gA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum) 		PF01039
(Carboxyl_trans)
PF08326
(ACC_central) 		4 PHE A1641
PHE A1649
ALA A1752
THR A1755
 None
 0.99A 3t3sC-5i6hA:
undetectable		 3t3sC-5i6hA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i6i ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN,ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN,ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum) 		PF01039
(Carboxyl_trans)
PF08326
(ACC_central) 		4 PHE A1641
PHE A1649
ALA A1752
THR A1755
 None
 0.96A 3t3sC-5i6iA:
undetectable		 3t3sC-5i6iA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00180
(Iso_dh) 		4 PHE A 142
ALA A 216
THR A 219
LEU A 145
 None
 0.80A 3t3sC-5j32A:
undetectable		 3t3sC-5j32A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jb3 30S RIBOSOMAL
PROTEIN S2

(Pyrococcus
abyssi) 		PF00318
(Ribosomal_S2) 		4 PHE B  83
ALA B  89
THR B  87
LEU B  59
 None
 0.89A 3t3sC-5jb3B:
undetectable		 3t3sC-5jb3B:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jp0 BETA-GLUCOSIDASE
BOGH3B

(Bacteroides
ovatus) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 PHE A 354
ASN A 319
ALA A 334
LEU A 361
 None
 0.94A 3t3sC-5jp0A:
undetectable		 3t3sC-5jp0A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mdx OXYGEN-EVOLVING
ENHANCER PROTEIN
1-1, CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF01716
(MSP) 		4 PHE O 227
PHE O 124
ASN O 187
LEU O 331
 None
 0.96A 3t3sC-5mdxO:
undetectable		 3t3sC-5mdxO:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mgy FAD:PROTEIN FMN
TRANSFERASE

(Pseudomonas
stutzeri) 		no annotation 4 PHE H 323
ALA H 322
THR H 337
LEU H 312
 None
 0.97A 3t3sC-5mgyH:
undetectable		 3t3sC-5mgyH:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2

(Synechocystis
sp. PCC 6803) 		no annotation 4 PHE b 244
PHE b 358
THR b 126
LEU b 270
 None
None
CLA  b1821 ( 4.7A)
None
 0.92A 3t3sC-5oy0b:
undetectable		 3t3sC-5oy0b:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u47 PENICILLIN BINDING
PROTEIN 2X

(Streptococcus
thermophilus) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer)
PF03793
(PASTA) 		4 PHE A 184
PHE A 174
ALA A 102
LEU A 130
 None
 0.81A 3t3sC-5u47A:
undetectable		 3t3sC-5u47A:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5usf TYROSYL-TRNA
SYNTHETASE, PUTATIVE

(Leishmania
donovani) 		PF00579
(tRNA-synt_1b) 		4 PHE A 528
ALA A 529
THR A 533
LEU A 509
 None
 0.80A 3t3sC-5usfA:
undetectable		 3t3sC-5usfA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vj1 MDCA

(Pseudomonas
aeruginosa) 		PF16957
(Mal_decarbox_Al) 		4 ASN A 264
PHE A 263
ALA A 266
LEU A 529
 None
 1.10A 3t3sC-5vj1A:
undetectable		 3t3sC-5vj1A:
20.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5wbg CYTOCHROME P450 2B6

(Homo sapiens) 		no annotation 4 PHE A 297
ALA A 298
THR A 302
LEU A 363
 9ZJ  A 502 ( 4.5A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
HEM  A 501 (-4.3A)
 0.47A 3t3sC-5wbgA:
55.8		 3t3sC-5wbgA:
65.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wly UDP-2,3-DIACYLGLUCOS
AMINE HYDROLASE

(Escherichia
coli) 		no annotation 4 PHE A   5
ALA A  35
THR A   3
LEU A 105
 None
 0.92A 3t3sC-5wlyA:
undetectable		 3t3sC-5wlyA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d6k POLYRIBONUCLEOTIDE
NUCLEOTIDYLTRANSFERA
SE

(Acinetobacter
baumannii) 		no annotation 4 PHE A 104
ALA A  47
THR A 144
LEU A 139
 None
 1.06A 3t3sC-6d6kA:
undetectable		 3t3sC-6d6kA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6elw PHOSPHOLIPID
HYDROPEROXIDE
GLUTATHIONE
PEROXIDASE,
MITOCHONDRIAL

(Homo sapiens) 		no annotation 4 PHE A  92
ASN A  76
ALA A  43
THR A  49
 None
None
SE7  A  46 ( 4.6A)
SE7  A  46 ( 3.7A)
 0.89A 3t3sC-6elwA:
undetectable		 3t3sC-6elwA:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ez8 FACTOR VIII INTRON
22 PROTEIN
HUNTINGTIN

(Homo sapiens) 		no annotation 4 PHE A2965
ALA B 202
THR B 205
LEU B 288
 None
 1.07A 3t3sC-6ez8A:
undetectable		 3t3sC-6ez8A:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fhe -

(-) 		no annotation 4 ASN A  34
ALA A  40
THR A  43
LEU A  50
 None
 0.89A 3t3sC-6fheA:
undetectable		 3t3sC-6fheA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g47 FIBER-1

(Human
mastadenovirus
G) 		no annotation 4 PHE A 357
ASN A 330
PHE A 329
LEU A 221
 None
 1.07A 3t3sC-6g47A:
undetectable		 3t3sC-6g47A:
10.64