SIMILAR PATTERNS OF AMINO ACIDS FOR 3T3S_B_9PLB1_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a0c | XYLOSE ISOMERASE (Thermoanaerobacteriumthermosulfurigenes) |
PF01261(AP_endonuc_2) | 4 | PHE A 211PHE A 208PHE A 186THR A 140 | None | 1.05A | 3t3sB-1a0cA:0.0 | 3t3sB-1a0cA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1avb | ARCELIN-1 (Phaseolusvulgaris) |
PF00139(Lectin_legB) | 4 | PHE A 221ASN A 224PHE A 65ALA A 63 | None | 1.06A | 3t3sB-1avbA:0.0 | 3t3sB-1avbA:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b89 | PROTEIN (CLATHRINHEAVY CHAIN) (Bos taurus) |
PF00637(Clathrin) | 4 | PHE A1490ASN A1459ALA A1486THR A1482 | None | 1.18A | 3t3sB-1b89A:0.0 | 3t3sB-1b89A:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1elj | MALTODEXTRIN-BINDINGPROTEIN (Pyrococcusfuriosus) |
PF13416(SBP_bac_8) | 4 | PHE A 40PHE A 283ALA A 284THR A 288 | None | 1.10A | 3t3sB-1eljA:undetectable | 3t3sB-1eljA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f02 | INTIMIN (Escherichiacoli) |
PF02368(Big_2)PF02369(Big_1)PF07979(Intimin_C) | 4 | ASN I 876PHE I 878ALA I 880THR I 766 | None | 1.13A | 3t3sB-1f02I:undetectable | 3t3sB-1f02I:18.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f5n | INTERFERON-INDUCEDGUANYLATE-BINDINGPROTEIN 1 (Homo sapiens) |
PF02263(GBP)PF02841(GBP_C) | 4 | PHE A 230PHE A 116ALA A 119THR A 98 | None | 1.18A | 3t3sB-1f5nA:0.1 | 3t3sB-1f5nA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fyh | INTERFERON GAMMA (Homo sapiens) |
PF00714(IFN-gamma) | 4 | PHE A 292PHE A 254ASN A 278PHE A 281 | None | 1.13A | 3t3sB-1fyhA:0.0 | 3t3sB-1fyhA:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1isc | IRON(III) SUPEROXIDEDISMUTASE (Escherichiacoli) |
PF00081(Sod_Fe_N)PF02777(Sod_Fe_C) | 4 | PHE A 103PHE A 106ALA A 108THR A 111 | None | 1.07A | 3t3sB-1iscA:0.0 | 3t3sB-1iscA:16.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jpu | GLYCEROLDEHYDROGENASE (Geobacillusstearothermophilus) |
PF00465(Fe-ADH) | 4 | PHE A 262PHE A 280ALA A 279THR A 282 | None | 1.18A | 3t3sB-1jpuA:0.0 | 3t3sB-1jpuA:23.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mi5 | TCR ALPHA CHAIN (Homo sapiens) |
PF07686(V-set)PF09291(DUF1968) | 4 | PHE D 187ASN D 191PHE D 193THR D 202 | None | 1.16A | 3t3sB-1mi5D:undetectable | 3t3sB-1mi5D:17.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n28 | PHOSPHOLIPASE A2,MEMBRANE ASSOCIATED (Homo sapiens) |
no annotation | 4 | ASN B 101PHE B 98ALA B 99THR B 12 | None | 1.18A | 3t3sB-1n28B:undetectable | 3t3sB-1n28B:12.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pd5 | CHLORAMPHENICOLACETYLTRANSFERASE (Escherichiacoli) |
PF00302(CAT) | 4 | PHE A 156PHE A 153ALA A 147THR A 93 | None | 0.99A | 3t3sB-1pd5A:undetectable | 3t3sB-1pd5A:17.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pp1 | P40 NUCLEOPROTEIN (Borna diseasevirus) |
PF06407(BDV_P40) | 4 | ASN X 301PHE X 299ALA X 303THR X 237 | None | 1.00A | 3t3sB-1pp1X:undetectable | 3t3sB-1pp1X:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qgc | PROTEIN (VIRUSCAPSID PROTEIN VP3) (Foot-and-mouthdisease virus) |
PF00073(Rhv) | 4 | PHE 3 209ASN 3 106ALA 3 203THR 3 89 | None | 1.04A | 3t3sB-1qgc3:undetectable | 3t3sB-1qgc3:18.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rf5 | 5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATESYNTHASE (Streptococcuspneumoniae) |
PF00275(EPSP_synthase) | 4 | PHE A 418ASN A 411ALA A 409THR A 380 | None | 1.18A | 3t3sB-1rf5A:undetectable | 3t3sB-1rf5A:23.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1smq | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESMALL CHAIN 1 (Saccharomycescerevisiae) |
PF00268(Ribonuc_red_sm) | 4 | PHE A 247PHE A 251ASN A 359THR A 277 | None | 1.12A | 3t3sB-1smqA:undetectable | 3t3sB-1smqA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t3i | PROBABLE CYSTEINEDESULFURASE (Synechocystissp.) |
PF00266(Aminotran_5) | 4 | PHE A 17ASN A 394PHE A 392ALA A 10 | None | 1.13A | 3t3sB-1t3iA:undetectable | 3t3sB-1t3iA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c8s | CYTOCHROME C-L (Methylobacteriumextorquens) |
PF13442(Cytochrome_CBB3) | 4 | PHE A 98ASN A 45ALA A 35THR A 33 | None | 0.97A | 3t3sB-2c8sA:undetectable | 3t3sB-2c8sA:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cas | CANINE PARVOVIRUSEMPTY CAPSID (STRAIND) VIRAL PROTEIN 2 (Carnivoreprotoparvovirus1) |
PF00740(Parvo_coat) | 4 | PHE A 185ASN A 485ALA A 189THR A 194 | None | 1.16A | 3t3sB-2casA:undetectable | 3t3sB-2casA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d1p | HYPOTHETICAL PROTEINYHELHYPOTHETICAL UPF0163PROTEIN YHEN (Escherichiacoli) |
PF02635(DrsE)PF04077(DsrH) | 4 | PHE A 3PHE A 23ALA A 26THR C 80 | None | 1.12A | 3t3sB-2d1pA:undetectable | 3t3sB-2d1pA:16.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dmw | SYNAPTOBREVIN-LIKE 1VARIANT (Homo sapiens) |
PF13774(Longin) | 4 | ASN A 84PHE A 85ALA A 82THR A 73 | None | 1.06A | 3t3sB-2dmwA:undetectable | 3t3sB-2dmwA:13.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dre | WATER-SOLUBLECHLOROPHYLL PROTEIN (Lepidiumvirginicum) |
PF00197(Kunitz_legume) | 4 | ASN A 80PHE A 122ALA A 82THR A 97 | None | 0.76A | 3t3sB-2dreA:undetectable | 3t3sB-2dreA:16.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2du7 | O-PHOSPHOSERYL-TRNASYNTHETASE (Methanocaldococcusjannaschii) |
PF01409(tRNA-synt_2d) | 4 | PHE A 409ASN A 382PHE A 383ALA A 384 | None | 1.17A | 3t3sB-2du7A:undetectable | 3t3sB-2du7A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2htv | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 4 | PHE A 422PHE A 410ALA A 98THR A 453 | None | 1.07A | 3t3sB-2htvA:undetectable | 3t3sB-2htvA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2htv | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 4 | PHE A 422PHE A 446ALA A 98THR A 453 | None | 1.02A | 3t3sB-2htvA:undetectable | 3t3sB-2htvA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i58 | SUGAR ABCTRANSPORTER,SUGAR-BINDINGPROTEIN (Streptococcuspneumoniae) |
PF13416(SBP_bac_8) | 4 | PHE A 383PHE A 172ALA A 182THR A 176 | None | 1.11A | 3t3sB-2i58A:undetectable | 3t3sB-2i58A:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i9k | MODIFICATIONMETHYLASE HHAI (Haemophilushaemolyticus) |
PF00145(DNA_methylase) | 4 | PHE A 79PHE A 18ALA A 105THR A 139 | NoneSAH A 328 (-4.9A)NoneNone | 0.95A | 3t3sB-2i9kA:undetectable | 3t3sB-2i9kA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oga | TRANSAMINASE (Streptomycesvenezuelae) |
PF01041(DegT_DnrJ_EryC1) | 4 | PHE A 187PHE A 189ALA A 53THR A 58 | None | 0.90A | 3t3sB-2ogaA:undetectable | 3t3sB-2ogaA:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pa6 | ENOLASE (Methanocaldococcusjannaschii) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | PHE A 317PHE A 300ALA A 301THR A 304 | None | 1.16A | 3t3sB-2pa6A:undetectable | 3t3sB-2pa6A:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v95 | CORTICOSTEROID-BINDING GLOBULIN (Rattusnorvegicus) |
PF00079(Serpin) | 4 | PHE A 79ASN A 16PHE A 19ALA A 20 | None | 1.16A | 3t3sB-2v95A:undetectable | 3t3sB-2v95A:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vu5 | NUCLEOSIDEDIPHOSPHATE KINASE (Bacillusanthracis) |
PF00334(NDK) | 4 | PHE A 57PHE A 58ALA A 123THR A 4 | None | 1.12A | 3t3sB-2vu5A:undetectable | 3t3sB-2vu5A:15.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x32 | CELLULOSE-BINDINGPROTEIN (Saccharophagusdegradans) |
PF04264(YceI) | 4 | PHE A 66ASN A 48PHE A 28THR A 52 | NoneNoneOTP A1174 ( 4.7A)None | 1.04A | 3t3sB-2x32A:undetectable | 3t3sB-2x32A:17.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xn6 | THYROXINE-BINDINGGLOBULIN (Homo sapiens) |
PF00079(Serpin) | 4 | PHE A 92ASN A 26PHE A 29ALA A 30 | None | 1.04A | 3t3sB-2xn6A:undetectable | 3t3sB-2xn6A:23.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yzj | 167AA LONGHYPOTHETICAL DUTPASE (Sulfurisphaeratokodaii) |
PF00692(dUTPase) | 4 | ASN A 124PHE A 81ALA A 126THR A 78 | None | 1.05A | 3t3sB-2yzjA:undetectable | 3t3sB-2yzjA:17.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ckz | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 4 | PHE A 422PHE A 410ALA A 98THR A 453 | None | 1.12A | 3t3sB-3ckzA:undetectable | 3t3sB-3ckzA:22.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ewb | 2-ISOPROPYLMALATESYNTHASE (Listeriamonocytogenes) |
PF00682(HMGL-like) | 4 | PHE X 265ASN X 229ALA X 239THR X 210 | None | 1.03A | 3t3sB-3ewbX:undetectable | 3t3sB-3ewbX:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eyt | UNCHARACTERIZEDPROTEIN SPOA0173 (Ruegeriapomeroyi) |
PF00578(AhpC-TSA) | 4 | PHE A 91PHE A 33ALA A 32THR A 67 | ACY A 202 (-4.9A)NoneNoneNone | 1.15A | 3t3sB-3eytA:undetectable | 3t3sB-3eytA:16.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f2b | DNA-DIRECTED DNAPOLYMERASE III ALPHACHAIN (Geobacilluskaustophilus) |
PF02811(PHP)PF07733(DNA_pol3_alpha)PF14579(HHH_6) | 4 | PHE A 963PHE A 960PHE A 869ALA A 870 | None | 1.11A | 3t3sB-3f2bA:undetectable | 3t3sB-3f2bA:19.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g3z | TRANSCRIPTIONALREGULATOR, MARRFAMILY (Neisseriameningitidis) |
PF01047(MarR) | 4 | PHE A 18PHE A 32ALA A 33THR A 37 | None | 0.92A | 3t3sB-3g3zA:undetectable | 3t3sB-3g3zA:18.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gsi | N,N-DIMETHYLGLYCINEOXIDASE (Arthrobacterglobiformis) |
PF01266(DAO)PF01571(GCV_T)PF08669(GCV_T_C)PF16350(FAO_M) | 4 | ASN A 57PHE A 65ALA A 66THR A 69 | None | 0.86A | 3t3sB-3gsiA:undetectable | 3t3sB-3gsiA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h1w | MANNOSE-6-PHOSPHATEISOMERASE (Salmonellaenterica) |
PF01238(PMI_typeI) | 4 | PHE A 78ASN A 389PHE A 321ALA A 322 | None | 1.17A | 3t3sB-3h1wA:undetectable | 3t3sB-3h1wA:24.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ifs | GLUCOSE-6-PHOSPHATEISOMERASE (Bacillusanthracis) |
PF00342(PGI) | 4 | PHE A 417ASN A 43ALA A 34THR A 31 | None | 1.19A | 3t3sB-3ifsA:undetectable | 3t3sB-3ifsA:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k13 | 5-METHYLTETRAHYDROFOLATE-HOMOCYSTEINEMETHYLTRANSFERASE (Bacteroidesthetaiotaomicron) |
PF00809(Pterin_bind) | 4 | ASN A 561PHE A 564ALA A 524THR A 527 | THH A 642 ( 3.3A)NoneNoneNone | 1.00A | 3t3sB-3k13A:undetectable | 3t3sB-3k13A:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mpn | TRANSPORTER (Aquifexaeolicus) |
PF00209(SNF) | 4 | PHE A 346PHE A 349ALA A 351THR A 354 | NoneNone NA A 751 (-4.9A) NA A 751 (-3.4A) | 1.10A | 3t3sB-3mpnA:undetectable | 3t3sB-3mpnA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n3k | UBIQUITINCARBOXYL-TERMINALHYDROLASE 8 (Homo sapiens) |
PF00443(UCH) | 4 | PHE A1081PHE A1083ASN A 797ALA A1075 | None | 1.15A | 3t3sB-3n3kA:undetectable | 3t3sB-3n3kA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nqn | UNCHARACTERIZEDPROTEIN (Deinococcusradiodurans) |
PF12723(DUF3809) | 4 | PHE A 108PHE A 106ALA A 105THR A 97 | MRD A 161 ( 4.7A)NoneMRD A 163 (-3.8A)MRD A 163 ( 3.7A) | 1.11A | 3t3sB-3nqnA:undetectable | 3t3sB-3nqnA:15.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o0d | TRIACYLGLYCEROLLIPASE (Yarrowialipolytica) |
PF01764(Lipase_3)PF03893(Lipase3_N) | 4 | PHE A 108PHE A 197ALA A 167THR A 136 | None | 1.16A | 3t3sB-3o0dA:undetectable | 3t3sB-3o0dA:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oos | ALPHA/BETA HYDROLASEFAMILY PROTEIN (Bacillusanthracis) |
PF00561(Abhydrolase_1) | 4 | PHE A 45ASN A 270PHE A 269THR A 252 | None | 1.15A | 3t3sB-3oosA:undetectable | 3t3sB-3oosA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pfo | PUTATIVEACETYLORNITHINEDEACETYLASE (Rhodopseudomonaspalustris) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 4 | PHE A 30PHE A 55ALA A 52THR A 64 | EDO A 504 (-4.8A)NoneNoneNone | 1.08A | 3t3sB-3pfoA:undetectable | 3t3sB-3pfoA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sdq | ALPHA-BISABOLENESYNTHASE (Abies grandis) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 4 | PHE A 373PHE A 380PHE A 370ALA A 368 | None | 1.11A | 3t3sB-3sdqA:undetectable | 3t3sB-3sdqA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t1b | TRANSCRIPTIONALREGULATOR, LYSRFAMILY (Vibrio cholerae) |
PF00126(HTH_1)PF03466(LysR_substrate) | 4 | PHE A 281PHE A 142ALA A 97THR A 102 | None | 1.12A | 3t3sB-3t1bA:undetectable | 3t3sB-3t1bA:20.37 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3tk3 | CYTOCHROME P450 2B4 (Oryctolaguscuniculus) |
PF00067(p450) | 4 | PHE A 115PHE A 297ALA A 298THR A 302 | NoneCPZ A 501 (-4.3A)CPZ A 501 (-3.5A)CPZ A 501 ( 3.7A) | 1.19A | 3t3sB-3tk3A:55.9 | 3t3sB-3tk3A:56.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tot | GLUTATHIONES-TRANSFERASEPROTEIN (Ralstoniasolanacearum) |
PF13410(GST_C_2)PF13417(GST_N_3) | 4 | ASN A 184PHE A 188ALA A 187THR A 190 | None | 1.05A | 3t3sB-3totA:undetectable | 3t3sB-3totA:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vsm | OCCLUSION-DERIVEDVIRUS ENVELOPEPROTEIN E66 (Autographacalifornicamultiplenucleopolyhedrovirus) |
PF04850(Baculo_E66) | 4 | PHE A 357PHE A 307ALA A 308THR A 311 | None | 1.13A | 3t3sB-3vsmA:undetectable | 3t3sB-3vsmA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wxo | CATALASE-PEROXIDASE (Synechococcuselongatus) |
PF00141(peroxidase) | 4 | ASN A 696PHE A 639ALA A 692THR A 643 | NA A 808 (-3.5A)NoneNoneNone | 1.07A | 3t3sB-3wxoA:undetectable | 3t3sB-3wxoA:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ae5 | SIGNAL TRANSDUCTIONPROTEIN TRAP (Staphylococcusaureus) |
no annotation | 4 | PHE A 118PHE A 120PHE A 94ALA A 134 | None | 0.87A | 3t3sB-4ae5A:undetectable | 3t3sB-4ae5A:14.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b7j | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 4 | PHE A 422PHE A 406ALA A 98THR A 452 | None | 1.09A | 3t3sB-4b7jA:undetectable | 3t3sB-4b7jA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4by6 | GENERAL NEGATIVEREGULATOR OFTRANSCRIPTIONSUBUNIT 1GENERAL NEGATIVEREGULATOR OFTRANSCRIPTIONSUBUNIT 5 (Saccharomycescerevisiae) |
PF04054(Not1)PF04153(NOT2_3_5) | 4 | ASN C 390PHE A1751ALA A1752THR A1755 | None | 1.12A | 3t3sB-4by6C:undetectable | 3t3sB-4by6C:17.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c41 | CORTICOSTEROID-BINDING GLOBULIN (Homo sapiens) |
PF00079(Serpin) | 4 | PHE A 87ASN A 21PHE A 24ALA A 25 | None | 1.02A | 3t3sB-4c41A:undetectable | 3t3sB-4c41A:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e14 | KYNURENINEFORMAMIDASE (Drosophilamelanogaster) |
PF07859(Abhydrolase_3) | 4 | PHE A 135PHE A 132PHE A 153ALA A 154 | None | 1.14A | 3t3sB-4e14A:undetectable | 3t3sB-4e14A:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eay | MANNONATEDEHYDRATASE (Escherichiacoli) |
PF03786(UxuA) | 4 | ASN A 211PHE A 212ALA A 213THR A 260 | None | 0.90A | 3t3sB-4eayA:undetectable | 3t3sB-4eayA:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ei8 | PLASMID REPLICATIONPROTEIN REPX (Bacillus cereus) |
PF00091(Tubulin) | 4 | PHE A 144PHE A 114ASN A 244PHE A 177 | None | 1.12A | 3t3sB-4ei8A:undetectable | 3t3sB-4ei8A:23.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f3e | CASA (Thermusthermophilus) |
PF09481(CRISPR_Cse1) | 4 | PHE A 441PHE A 440ALA A 370THR A 367 | None | 1.16A | 3t3sB-4f3eA:undetectable | 3t3sB-4f3eA:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g76 | PHOSPHODIESTERASE (Pseudomonasaeruginosa) |
PF14859(Colicin_M) | 4 | PHE A 85PHE A 148ALA A 149THR A 153 | None | 1.03A | 3t3sB-4g76A:undetectable | 3t3sB-4g76A:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gpn | 6-PHOSPHO-BETA-D-GLUCOSIDASE (Streptococcusmutans) |
PF00232(Glyco_hydro_1) | 4 | PHE A 174ASN A 192PHE A 144ALA A 210 | None | 1.08A | 3t3sB-4gpnA:undetectable | 3t3sB-4gpnA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hpf | POTASSIUM CHANNELSUBFAMILY U MEMBER 1 (Homo sapiens) |
PF03493(BK_channel_a) | 4 | PHE A 517PHE A 895ALA A 894THR A 899 | None | 1.16A | 3t3sB-4hpfA:undetectable | 3t3sB-4hpfA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ifq | NUCLEOPORIN NUP192 (Saccharomycescerevisiae) |
PF11894(Nup192) | 4 | PHE A 238PHE A 325ALA A 326THR A 329 | None | 1.15A | 3t3sB-4ifqA:undetectable | 3t3sB-4ifqA:19.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iss | ALLOPHANATEHYDROLASE (Kluyveromyceslactis) |
PF01425(Amidase) | 4 | PHE A 561PHE A 558PHE A 585ALA A 487 | None | 1.09A | 3t3sB-4issA:undetectable | 3t3sB-4issA:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jw1 | EFFECTOR PROTEIN B (Legionellapneumophila) |
no annotation | 4 | PHE A 52PHE A 280PHE A 289ALA A 290 | None | 1.18A | 3t3sB-4jw1A:undetectable | 3t3sB-4jw1A:23.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kw7 | ARSENICMETHYLTRANSFERASE (Cyanidioschyzonsp. 5508) |
PF13847(Methyltransf_31) | 4 | PHE A 135PHE A 136ASN A 143ALA A 101 | None | 1.18A | 3t3sB-4kw7A:undetectable | 3t3sB-4kw7A:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nen | INTEGRIN ALPHA-X (Homo sapiens) |
PF00092(VWA)PF01839(FG-GAP)PF08441(Integrin_alpha2) | 4 | PHE A 18PHE A 11ALA A 56THR A 54 | None | 0.98A | 3t3sB-4nenA:undetectable | 3t3sB-4nenA:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ppm | AMINOTRANSFERASE (Serratia sp.FS14) |
PF00202(Aminotran_3) | 4 | PHE A 714PHE A 841ALA A 840THR A 843 | None | 1.07A | 3t3sB-4ppmA:undetectable | 3t3sB-4ppmA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qi6 | CELLOBIOSEDEHYDROGENASE (Crassicarponhotsonii) |
PF00732(GMC_oxred_N)PF00734(CBM_1)PF05199(GMC_oxred_C)PF16010(CDH-cyt) | 4 | PHE A 35PHE A 33ALA A 82THR A 91 | None | 1.17A | 3t3sB-4qi6A:undetectable | 3t3sB-4qi6A:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qs9 | HEXOKINASE-1 (Arabidopsisthaliana) |
PF00349(Hexokinase_1)PF03727(Hexokinase_2) | 4 | PHE A 174ASN A 212PHE A 144ALA A 214 | None | 1.10A | 3t3sB-4qs9A:undetectable | 3t3sB-4qs9A:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tkt | AT-LESS POLYKETIDESYNTHASE (Streptomycesplatensis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 4 | PHE A3537ASN A3482ALA A3480THR A3478 | None | 1.18A | 3t3sB-4tktA:undetectable | 3t3sB-4tktA:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xru | HEN1 (Capnocytophagagingivalis) |
no annotation | 4 | PHE C 67ASN C 151ALA C 123THR C 175 | None | 0.97A | 3t3sB-4xruC:undetectable | 3t3sB-4xruC:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yip | SUPEROXIDE DISMUTASE[MN/FE] (Streptococcusmutans) |
PF00081(Sod_Fe_N)PF02777(Sod_Fe_C) | 4 | PHE A 109PHE A 112ALA A 114THR A 117 | None | 1.04A | 3t3sB-4yipA:undetectable | 3t3sB-4yipA:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zcf | RESTRICTIONENDONUCLEASEECOP15I,MODIFICATION SUBUNIT (Escherichiacoli) |
PF01555(N6_N4_Mtase) | 4 | PHE A 407PHE A 414ALA A 417THR A 446 | None | 1.15A | 3t3sB-4zcfA:undetectable | 3t3sB-4zcfA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ahr | DNA CROSS-LINKREPAIR 1A PROTEIN (Homo sapiens) |
PF07522(DRMBL)PF12706(Lactamase_B_2) | 4 | PHE A 745PHE A 717ALA A 716THR A 713 | None | 1.06A | 3t3sB-5ahrA:undetectable | 3t3sB-5ahrA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b04 | PROBABLE TRANSLATIONINITIATION FACTOREIF-2B SUBUNITEPSILON (Schizosaccharomycespombe) |
PF00132(Hexapep)PF00483(NTP_transferase) | 4 | PHE I 123ASN I 228ALA I 232THR I 235 | None | 1.05A | 3t3sB-5b04I:undetectable | 3t3sB-5b04I:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ce0 | NATIVE CONSERPINWITH Z-VARIANT(E342K) (syntheticconstruct) |
PF00079(Serpin) | 4 | PHE A 70ASN A 8PHE A 11ALA A 12 | None | 1.05A | 3t3sB-5ce0A:undetectable | 3t3sB-5ce0A:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gui | CHAPERONE PROTEINCLPC1, CHLOROPLASTIC (Arabidopsisthaliana) |
PF02861(Clp_N) | 4 | PHE A 95PHE A 98ALA A 177THR A 174 | NoneNonePO4 A 302 ( 4.5A)PO4 A 302 (-3.0A) | 1.12A | 3t3sB-5guiA:undetectable | 3t3sB-5guiA:16.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h4e | BETA 1-3 GLUCANASE (Clostridiumbeijerinckii) |
no annotation | 4 | PHE A 434PHE A 444ASN A 526ALA A 552 | None | 1.14A | 3t3sB-5h4eA:undetectable | 3t3sB-5h4eA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hgc | SERPIN (Taeniopygiaguttata) |
PF00079(Serpin) | 4 | PHE A 101ASN A 35PHE A 38ALA A 39 | None | 0.95A | 3t3sB-5hgcA:undetectable | 3t3sB-5hgcA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i8i | UREA AMIDOLYASE (Kluyveromyceslactis) |
PF00289(Biotin_carb_N)PF01425(Amidase)PF02626(CT_A_B)PF02682(CT_C_D)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 4 | PHE A 561PHE A 558PHE A 585ALA A 487 | None | 1.09A | 3t3sB-5i8iA:undetectable | 3t3sB-5i8iA:14.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jou | ALPHA-XYLOSIDASEBOGH31A (Bacteroidesovatus) |
PF01055(Glyco_hydro_31)PF16338(DUF4968)PF17137(DUF5110) | 4 | PHE A 169ASN A 647ALA A 649THR A 758 | None | 1.17A | 3t3sB-5jouA:undetectable | 3t3sB-5jouA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kkb | MANNOSYL-OLIGOSACCHARIDE1,2-ALPHA-MANNOSIDASE IA (Mus musculus) |
PF01532(Glyco_hydro_47) | 4 | ASN A 394PHE A 417ALA A 350THR A 354 | NoneNoneMAN A 708 ( 3.3A)None | 1.19A | 3t3sB-5kkbA:undetectable | 3t3sB-5kkbA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lc5 | NADH-UBIQUINONEOXIDOREDUCTASE CHAIN1 (Bos taurus) |
PF00146(NADHdh) | 4 | PHE H 186PHE H 270ASN H 235ALA H 239 | None | 0.94A | 3t3sB-5lc5H:undetectable | 3t3sB-5lc5H:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mpt | CITRININ POLYKETIDESYNTHASE (Monascuspurpureus) |
PF08242(Methyltransf_12) | 4 | PHE A1838PHE A1927ALA A1928THR A1932 | None | 1.05A | 3t3sB-5mptA:undetectable | 3t3sB-5mptA:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mqp | GLYCOSIDE HYDROLASEBT_1002 (Bacteroidesthetaiotaomicron) |
no annotation | 4 | PHE A 383PHE A 319ALA A 372THR A 297 | None | 1.12A | 3t3sB-5mqpA:undetectable | 3t3sB-5mqpA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5net | O1 MANISA VP3 (Foot-and-mouthdisease virus) |
PF00073(Rhv) | 4 | PHE 3 209ASN 3 106ALA 3 203THR 3 89 | None | 1.15A | 3t3sB-5net3:undetectable | 3t3sB-5net3:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nsq | AMINOPEPTIDASE,PUTATIVE (Trypanosomabrucei) |
PF00883(Peptidase_M17) | 4 | PHE A 28PHE A 188ALA A 155THR A 206 | None | 1.13A | 3t3sB-5nsqA:undetectable | 3t3sB-5nsqA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t2x | UNCHARACTERIZEDPROTEIN LPG1670 (Legionellapneumophila) |
no annotation | 4 | PHE A 83ASN A 218PHE A 222ALA A 220 | None | 1.10A | 3t3sB-5t2xA:undetectable | 3t3sB-5t2xA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t5i | TUNGSTENFORMYLMETHANOFURANDEHYDROGENASESUBUNIT BTUNGSTENFORMYLMETHANOFURANDEHYDROGENASESUBUNIT FWDD (Methanothermobactersp. CaT2;Methanothermobacterwolfeii) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 4 | PHE D 100ASN D 85PHE B 349THR B 372 | MGD B 503 (-3.7A)MGD B 503 (-3.2A)NoneNone | 1.07A | 3t3sB-5t5iD:undetectable | 3t3sB-5t5iD:15.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u0i | GLUTAMINASE KIDNEYISOFORM,MITOCHONDRIAL (Homo sapiens) |
PF12796(Ank_2) | 4 | ASN A 556PHE A 559ALA A 560THR A 563 | None | 1.06A | 3t3sB-5u0iA:undetectable | 3t3sB-5u0iA:14.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uen | ADENOSINE RECEPTORA1,SOLUBLECYTOCHROMEB562,ADENOSINERECEPTOR A1 (Escherichiacoli;Homo sapiens) |
PF00001(7tm_1)PF07361(Cytochrom_B562) | 4 | PHE A1061PHE A1065ALA A 222THR A 225 | None | 1.17A | 3t3sB-5uenA:undetectable | 3t3sB-5uenA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ux2 | ALDEHYDEDECARBONYLASE (Synechococcussp. RS9917) |
no annotation | 4 | PHE A 81PHE A 111ALA A 115THR A 192 | None | 0.87A | 3t3sB-5ux2A:undetectable | 3t3sB-5ux2A:9.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w4z | RIBOFLAVIN LYASE (Herbiconiux) |
no annotation | 4 | PHE A 14ASN A 16ALA A 63THR A 143 | RBF A 502 (-3.6A)RBF A 502 (-3.8A)RBF A 502 ( 3.8A)None | 1.05A | 3t3sB-5w4zA:undetectable | 3t3sB-5w4zA:11.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5wbg | CYTOCHROME P450 2B6 (Homo sapiens) |
no annotation | 4 | PHE A 108PHE A 297ALA A 298THR A 302 | 9ZJ A 502 (-4.4A)9ZJ A 502 ( 4.5A)9ZJ A 502 ( 3.5A)9ZJ A 502 ( 3.9A) | 0.41A | 3t3sB-5wbgA:56.0 | 3t3sB-5wbgA:65.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c0w | CENTROMERE PROTEIN N (Homo sapiens) |
no annotation | 4 | PHE K 108PHE K 104ALA K 161THR K 163 | PHE K 108 ( 1.3A)PHE K 104 ( 1.3A)ALA K 161 ( 0.0A)THR K 163 ( 0.8A) | 1.16A | 3t3sB-6c0wK:undetectable | 3t3sB-6c0wK:10.50 |