SIMILAR PATTERNS OF AMINO ACIDS FOR 3T3R_A_9PLA501_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a7j | PHOSPHORIBULOKINASE (Rhodobactersphaeroides) |
PF00485(PRK) | 5 | PHE A 25VAL A 21ILE A 152GLY A 153LEU A 268 | None | 0.82A | 3t3rA-1a7jA:0.0 | 3t3rA-1a7jA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e1t | LYSYL-TRNASYNTHETASE, HEATINDUCIBLE (Escherichiacoli) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon) | 5 | PHE A 297PHE A 415ILE A 476GLY A 477LEU A 484 | NoneNoneNoneLAD A 601 (-3.4A)None | 1.15A | 3t3rA-1e1tA:0.0 | 3t3rA-1e1tA:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e1t | LYSYL-TRNASYNTHETASE, HEATINDUCIBLE (Escherichiacoli) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon) | 5 | PHE A 297PHE A 485PHE A 415ILE A 476GLY A 477 | NoneNoneNoneNoneLAD A 601 (-3.4A) | 1.11A | 3t3rA-1e1tA:0.0 | 3t3rA-1e1tA:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ek2 | EPOXIDE HYDROLASE (Mus musculus) |
PF00561(Abhydrolase_1)PF13419(HAD_2) | 5 | PHE A 406ILE A 427THR A 402LEU A 462PHE A 265 | CDU A1100 (-4.6A)NoneNoneNoneNone | 0.93A | 3t3rA-1ek2A:undetectable | 3t3rA-1ek2A:23.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g59 | GLUTAMYL-TRNASYNTHETASE (Thermusthermophilus) |
PF00749(tRNA-synt_1c) | 5 | PHE A 289PHE A 284PHE A 24GLY A 274PHE A 293 | NoneNoneNone U B 513 ( 3.3A)None | 1.12A | 3t3rA-1g59A:0.0 | 3t3rA-1g59A:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iip | CYCLOPHILIN 40 (Bos taurus) |
PF00160(Pro_isomerase)PF13176(TPR_7) | 5 | PHE A 132PHE A 48PHE A 73ILE A 178LEU A 34 | None | 1.17A | 3t3rA-1iipA:0.0 | 3t3rA-1iipA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s9a | CHLOROCATECHOL1,2-DIOXYGENASE (Rhodococcusopacus) |
PF00775(Dioxygenase_C)PF04444(Dioxygenase_N) | 5 | PHE A 106PHE A 252ILE A 197THR A 70LEU A 233 | None | 1.15A | 3t3rA-1s9aA:0.0 | 3t3rA-1s9aA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uhg | OVALBUMIN (Gallus gallus) |
PF00079(Serpin) | 6 | VAL A 383PHE A 15ASN A 26ILE A 27GLY A 380LEU A 252 | None | 1.32A | 3t3rA-1uhgA:0.0 | 3t3rA-1uhgA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v9t | CYCLOPHILIN B (Escherichiacoli) |
PF00160(Pro_isomerase) | 5 | PHE A 103PHE A 32PHE A 46ILE A 159LEU A 18 | None | 1.11A | 3t3rA-1v9tA:undetectable | 3t3rA-1v9tA:17.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vdc | NADPH DEPENDENTTHIOREDOXINREDUCTASE (Arabidopsisthaliana) |
PF07992(Pyr_redox_2) | 5 | VAL A 49ASN A 51ILE A 296LEU A 64PHE A 68 | FAD A 400 (-3.5A)FAD A 400 ( 3.2A)NoneNoneNone | 1.10A | 3t3rA-1vdcA:undetectable | 3t3rA-1vdcA:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vdc | NADPH DEPENDENTTHIOREDOXINREDUCTASE (Arabidopsisthaliana) |
PF07992(Pyr_redox_2) | 5 | VAL A 204PHE A 121ILE A 243GLY A 152LEU A 239 | None | 1.16A | 3t3rA-1vdcA:undetectable | 3t3rA-1vdcA:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vfn | PURINE-NUCLEOSIDEPHOSPHORYLASE (Bos taurus) |
PF01048(PNP_UDP_1) | 5 | VAL A 102PHE A 103ILE A 53LEU A 106PHE A 70 | None | 1.06A | 3t3rA-1vfnA:undetectable | 3t3rA-1vfnA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2amc | PHENYLALANYL-TRNASYNTHETASE BETACHAIN (Thermusthermophilus) |
PF01409(tRNA-synt_2d)PF01588(tRNA_bind)PF03147(FDX-ACB)PF03483(B3_4)PF03484(B5) | 5 | PHE B 338PHE B 360PHE B 263ILE B 300GLY B 312 | TYR B 999 (-4.5A)TYR B 999 ( 4.8A)NoneNoneNone | 1.11A | 3t3rA-2amcB:undetectable | 3t3rA-2amcB:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ekd | HYPOTHETICAL PROTEINPH0250 (Pyrococcushorikoshii) |
PF03192(DUF257) | 5 | PHE A 150PHE A 152PHE A 10LEU A 29PHE A 6 | None | 1.17A | 3t3rA-2ekdA:undetectable | 3t3rA-2ekdA:18.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2esn | PROBABLETRANSCRIPTIONALREGULATOR (Pseudomonasaeruginosa) |
PF00126(HTH_1)PF03466(LysR_substrate) | 5 | PHE A 101PHE A 151PHE A 103GLY A 297LEU A 117 | None | 1.04A | 3t3rA-2esnA:undetectable | 3t3rA-2esnA:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ewy | BETA-SECRETASE 2 (Homo sapiens) |
PF00026(Asp) | 5 | PHE A 54VAL A 113PHE A 152ILE A 36GLY A 37 | None | 1.02A | 3t3rA-2ewyA:undetectable | 3t3rA-2ewyA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f8t | ARGONAUTE PROTEIN (Aquifexaeolicus) |
PF02171(Piwi) | 5 | PHE A 88PHE A 21GLY A 302LEU A 100PHE A 91 | None | 0.98A | 3t3rA-2f8tA:undetectable | 3t3rA-2f8tA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i6h | HYPOTHETICAL PROTEINATU0120 (Agrobacteriumfabrum) |
PF06041(DUF924) | 5 | PHE A 15PHE A 31GLY A 20LEU A 66PHE A 35 | None | 1.13A | 3t3rA-2i6hA:undetectable | 3t3rA-2i6hA:18.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ilx | 2',3'-CYCLIC-NUCLEOTIDE3'-PHOSPHODIESTERASE (Rattusnorvegicus) |
PF05881(CNPase) | 5 | PHE A 110PHE A 46GLY A 196LEU A 192PHE A 39 | None | 1.13A | 3t3rA-2ilxA:undetectable | 3t3rA-2ilxA:18.37 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2pg6 | CYTOCHROME P450 2A6 (Homo sapiens) |
PF00067(p450) | 10 | PHE A 107PHE A 111VAL A 117PHE A 118PHE A 209ILE A 300GLY A 301THR A 305LEU A 370PHE A 480 | NoneNoneHEM A 500 (-3.7A)NoneNoneNoneHEM A 500 ( 4.7A)HEM A 500 (-3.6A)HEM A 500 ( 3.8A)None | 0.62A | 3t3rA-2pg6A:63.9 | 3t3rA-2pg6A:99.58 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2pg6 | CYTOCHROME P450 2A6 (Homo sapiens) |
PF00067(p450) | 5 | PHE A 271PHE A 267GLY A 115LEU A 298PHE A 440 | NoneNoneNoneNoneHEM A 500 (-3.9A) | 1.15A | 3t3rA-2pg6A:63.9 | 3t3rA-2pg6A:99.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v7b | BENZOATE-COENZYME ALIGASE (Paraburkholderiaxenovorans) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 5 | PHE A 90GLY A 241THR A 211LEU A 189PHE A 187 | None | 1.07A | 3t3rA-2v7bA:undetectable | 3t3rA-2v7bA:21.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vsq | SURFACTIN SYNTHETASESUBUNIT 3 (Bacillussubtilis) |
PF00501(AMP-binding)PF00550(PP-binding)PF00668(Condensation)PF00975(Thioesterase)PF13193(AMP-binding_C) | 5 | PHE A 665PHE A 661ILE A 531GLY A 530LEU A 483 | None | 1.16A | 3t3rA-2vsqA:undetectable | 3t3rA-2vsqA:17.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2whd | THIOREDOXINREDUCTASE (Hordeum vulgare) |
PF07992(Pyr_redox_2) | 5 | VAL A 216PHE A 131ILE A 253GLY A 164LEU A 249 | NoneNoneFLC A 401 (-4.2A)FLC A 401 ( 4.0A)None | 1.13A | 3t3rA-2whdA:undetectable | 3t3rA-2whdA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wtk | STE20-RELATED KINASEADAPTER PROTEINALPHA (Homo sapiens) |
PF00069(Pkinase) | 5 | PHE B 149PHE B 415ILE B 75GLY B 76LEU B 202 | ANP B 432 ( 4.9A)ANP B 432 ( 4.9A)ANP B 432 (-4.4A)ANP B 432 (-3.4A)ANP B 432 ( 4.7A) | 1.13A | 3t3rA-2wtkB:undetectable | 3t3rA-2wtkB:24.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xty | QNRB1 (Klebsiellapneumoniae) |
PF00805(Pentapeptide)PF13599(Pentapeptide_4) | 5 | PHE A 96PHE A 101ILE A 86LEU A 131PHE A 126 | None | 1.12A | 3t3rA-2xtyA:undetectable | 3t3rA-2xtyA:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zoo | PROBABLE NITRITEREDUCTASE (Pseudoalteromonashaloplanktis) |
PF00034(Cytochrom_C)PF00394(Cu-oxidase)PF07732(Cu-oxidase_3) | 5 | PHE A 72PHE A 111VAL A 91PHE A 113ILE A 86 | None | 1.11A | 3t3rA-2zooA:undetectable | 3t3rA-2zooA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c2g | SYS-1 PROTEIN (Caenorhabditiselegans) |
no annotation | 5 | VAL A 460ILE A 468GLY A 466LEU A 496PHE A 527 | None | 1.00A | 3t3rA-3c2gA:undetectable | 3t3rA-3c2gA:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dkh | LACCASE-1 (Melanocarpusalbomyces) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 5 | PHE A 288VAL A 217PHE A 310ILE A 200LEU A 227 | NoneNAG A 760 (-3.9A)NoneNoneNone | 1.05A | 3t3rA-3dkhA:undetectable | 3t3rA-3dkhA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e3x | BIPA (Vibrioparahaemolyticus) |
PF00679(EFG_C) | 5 | PHE A 179PHE A 175ASN A 142ILE A 139GLY A 138 | None | 0.88A | 3t3rA-3e3xA:undetectable | 3t3rA-3e3xA:23.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ed4 | ARYLSULFATASE (Escherichiacoli) |
PF00884(Sulfatase) | 5 | VAL A 241ASN A 288THR A 68LEU A 53PHE A 316 | None | 1.03A | 3t3rA-3ed4A:undetectable | 3t3rA-3ed4A:23.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fds | DNA POLYMERASESLIDING CLAMP C (Sulfolobussolfataricus) |
PF00705(PCNA_N)PF02747(PCNA_C) | 5 | VAL D 6PHE D 57ILE D 15LEU D 91PHE D 28 | None | 0.72A | 3t3rA-3fdsD:undetectable | 3t3rA-3fdsD:18.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ghy | KETOPANTOATEREDUCTASE PROTEIN (Ralstoniasolanacearum) |
PF02558(ApbA)PF08546(ApbA_C) | 5 | PHE A 109VAL A 294ILE A 249GLY A 246LEU A 205 | None | 1.12A | 3t3rA-3ghyA:undetectable | 3t3rA-3ghyA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hc7 | GENE 12 PROTEIN (Mycobacteriumvirus D29) |
PF01083(Cutinase) | 5 | VAL A 200PHE A 193ILE A 222GLY A 184LEU A 204 | None | 1.10A | 3t3rA-3hc7A:undetectable | 3t3rA-3hc7A:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i9v | NADH-QUINONEOXIDOREDUCTASESUBUNIT 2NADH-QUINONEOXIDOREDUCTASESUBUNIT 3 (Thermusthermophilus) |
PF00384(Molybdopterin)PF01257(2Fe-2S_thioredx)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4)PF10588(NADH-G_4Fe-4S_3)PF13510(Fer2_4) | 5 | ILE 3 211GLY 3 212THR 2 58LEU 3 218PHE 3 191 | SF4 3 785 ( 4.5A)NoneNoneNoneNone | 1.05A | 3t3rA-3i9v3:undetectable | 3t3rA-3i9v3:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kkc | TETR FAMILYTRANSCRIPTIONALREGULATOR (Streptococcusagalactiae) |
PF00440(TetR_N)PF14278(TetR_C_8) | 5 | PHE A 65PHE A 69PHE A 106ILE A 95LEU A 114 | None | 1.06A | 3t3rA-3kkcA:undetectable | 3t3rA-3kkcA:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kq4 | CUBILIN (Homo sapiens) |
PF00431(CUB) | 5 | PHE B1270PHE B1210PHE B1207LEU B1205PHE B1176 | None | 1.13A | 3t3rA-3kq4B:undetectable | 3t3rA-3kq4B:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lca | PROTEIN TOM71 (Saccharomycescerevisiae) |
PF00515(TPR_1)PF13181(TPR_8)PF14559(TPR_19) | 5 | PHE A 273PHE A 276ASN A 379ILE A 353LEU A 302 | None | 0.99A | 3t3rA-3lcaA:undetectable | 3t3rA-3lcaA:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mcp | GLUCOKINASE (Parabacteroidesdistasonis) |
PF00480(ROK) | 5 | PHE A 342ILE A 274GLY A 243LEU A 250PHE A 158 | None | 1.16A | 3t3rA-3mcpA:undetectable | 3t3rA-3mcpA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n23 | SODIUM/POTASSIUM-TRANSPORTING ATPASESUBUNIT BETA-1 (Sus scrofa) |
PF00287(Na_K-ATPase) | 5 | PHE B 186ASN B 282ILE B 283GLY B 280LEU B 240 | None | 0.94A | 3t3rA-3n23B:undetectable | 3t3rA-3n23B:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pj0 | LMO0305 PROTEIN (Listeriamonocytogenes) |
PF01212(Beta_elim_lyase) | 5 | VAL A 333ILE A 317GLY A 316LEU A 269PHE A 351 | None | 1.07A | 3t3rA-3pj0A:undetectable | 3t3rA-3pj0A:23.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qqy | RIBOSOMAL PROTEIN3/HOMINGENDONUCLEASE-LIKEPROTEIN FUSION (Ophiostomanovo-ulmi) |
PF00961(LAGLIDADG_1) | 5 | VAL A 252PHE A 253PHE A 237GLY A 220LEU A 171 | None | 0.99A | 3t3rA-3qqyA:undetectable | 3t3rA-3qqyA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s6m | PEPTIDYL-PROLYLCIS-TRANS ISOMERASE (Burkholderiapseudomallei) |
PF00160(Pro_isomerase) | 5 | PHE A 98PHE A 27PHE A 41ILE A 157LEU A 13 | None | 1.14A | 3t3rA-3s6mA:undetectable | 3t3rA-3s6mA:15.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t5v | NUCLEAR MRNA EXPORTPROTEIN THP1 (Saccharomycescerevisiae) |
PF01399(PCI) | 5 | PHE B 199VAL B 179ASN B 183LEU B 176PHE B 211 | None | 1.09A | 3t3rA-3t5vB:undetectable | 3t3rA-3t5vB:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wud | GALECTIN (Xenopus laevis) |
PF00337(Gal-bind_lectin) | 6 | VAL A 99PHE A 107PHE A 31ILE A 33LEU A 101PHE A 80 | None | 1.39A | 3t3rA-3wudA:undetectable | 3t3rA-3wudA:15.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bdu | GREEN FLUORESCENTPROTEIN, APOPTOSISREGULATOR BAX (Aequoreavictoria;Homo sapiens) |
PF00452(Bcl-2)PF01353(GFP) | 5 | PHE A 71VAL A 112ASN A 121ILE A 14PHE A 8 | NoneNoneCR2 A 65 ( 4.3A)NoneNone | 1.17A | 3t3rA-4bduA:undetectable | 3t3rA-4bduA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eut | SERINE/THREONINE-PROTEIN KINASE TBK1 (Homo sapiens) |
PF00069(Pkinase) | 5 | VAL A 280ILE A 207GLY A 208LEU A 277PHE A 112 | None | 0.92A | 3t3rA-4eutA:undetectable | 3t3rA-4eutA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4euu | SERINE/THREONINE-PROTEIN KINASE TBK1 (Homo sapiens) |
PF00069(Pkinase) | 5 | VAL A 280ILE A 207GLY A 208LEU A 277PHE A 112 | None | 0.93A | 3t3rA-4euuA:undetectable | 3t3rA-4euuA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdj | N-ACETYLGALACTOSAMINE-6-SULFATASE (Homo sapiens) |
PF00884(Sulfatase)PF14707(Sulfatase_C) | 5 | PHE A 284PHE A 282PHE A 72LEU A 372PHE A 69 | None | 1.02A | 3t3rA-4fdjA:undetectable | 3t3rA-4fdjA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g0b | HYDROXYCINNAMOYL-COASHIKIMATE/QUINATEHYDROXYCINNAMOYLTRANSFERASE (Coffeacanephora) |
PF02458(Transferase) | 5 | PHE A 389VAL A 39PHE A 41GLY A 394LEU A 117 | None | 1.11A | 3t3rA-4g0bA:undetectable | 3t3rA-4g0bA:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gkp | SPINDLE POLEBODY-ASSOCIATEDPROTEIN VIK1 ([Candida]glabrata) |
PF16796(Microtub_bd) | 5 | PHE A 555VAL A 397PHE A 557PHE A 548LEU A 571 | None | 0.90A | 3t3rA-4gkpA:undetectable | 3t3rA-4gkpA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4grc | PUTATIVE MEMBRANEPROTEIN (Streptomycescoelicolor) |
PF04261(Dyp_perox) | 5 | PHE A 363VAL A 274GLY A 373LEU A 165PHE A 168 | HEM A 502 (-3.9A)NoneNoneNoneNone | 0.72A | 3t3rA-4grcA:undetectable | 3t3rA-4grcA:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gs1 | DYP-TYPE PEROXIDASE (Thermobifidacellulosilytica) |
PF04261(Dyp_perox) | 5 | PHE A 373VAL A 276GLY A 383LEU A 165PHE A 168 | HEM A 501 (-4.0A)NoneNoneGOL A 503 (-3.8A)None | 0.76A | 3t3rA-4gs1A:undetectable | 3t3rA-4gs1A:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gt2 | PUTATIVEUNCHARACTERIZEDPROTEIN SCO3963 (Streptomycescoelicolor) |
no annotation | 5 | PHE B 390VAL B 290GLY B 400LEU B 177PHE B 180 | HEM B 501 (-3.9A)NoneNoneNoneNone | 0.75A | 3t3rA-4gt2B:undetectable | 3t3rA-4gt2B:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ke4 | HYDROXYCINNAMOYL-COA:SHIKIMATEHYDROXYCINNAMOYLTRANSFERASE (Sorghum bicolor) |
PF02458(Transferase) | 5 | PHE A 403VAL A 39PHE A 41GLY A 408LEU A 127 | None | 1.15A | 3t3rA-4ke4A:undetectable | 3t3rA-4ke4A:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lgi | UNCHARACTERIZEDPROTEIN (Escherichiacoli) |
PF13678(Peptidase_M85) | 5 | VAL A 94PHE A 90ILE A 108GLY A 106LEU A 84 | None | 1.02A | 3t3rA-4lgiA:undetectable | 3t3rA-4lgiA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mq0 | PARKIA BIGLOBOSALECTIN (PBL) (Parkiabiglobosa) |
PF01419(Jacalin) | 5 | PHE A 276PHE A 168PHE A 170PHE A 246ILE A 190 | None | 1.12A | 3t3rA-4mq0A:undetectable | 3t3rA-4mq0A:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n0l | PREDICTED COMPONENTOF ATHERMOPHILE-SPECIFICDNA REPAIR SYSTEM,CONTAINS A RAMPDOMAIN (Methanopyruskandleri) |
PF03787(RAMPs) | 5 | PHE A 224VAL A 49GLY A 266LEU A 54PHE A 270 | None | 1.11A | 3t3rA-4n0lA:undetectable | 3t3rA-4n0lA:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o2i | NON-LEE ENCODED TYPEIII EFFECTOR C (Citrobacterrodentium) |
PF13678(Peptidase_M85) | 5 | VAL A 94PHE A 90ILE A 108GLY A 106LEU A 84 | None | 1.01A | 3t3rA-4o2iA:undetectable | 3t3rA-4o2iA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pfi | TRAP DICARBOXYLATETRANSPORTER-DCTPSUBUNIT (Marinobacterhydrocarbonoclasticus) |
PF03480(DctP) | 5 | PHE A 163PHE A 149GLY A 121LEU A 129PHE A 145 | None | 0.90A | 3t3rA-4pfiA:undetectable | 3t3rA-4pfiA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rld | ASPARTIC PROTEASEBLA G 2 (Blattellagermanica) |
PF00026(Asp) | 5 | VAL A 38PHE A 167ILE A 123LEU A 89PHE A 140 | None | 1.01A | 3t3rA-4rldA:undetectable | 3t3rA-4rldA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rlq | BENZOATE-COENZYME ALIGASE (Rhodopseudomonaspalustris) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 5 | PHE A 80GLY A 231THR A 201LEU A 179PHE A 177 | None | 1.08A | 3t3rA-4rlqA:undetectable | 3t3rA-4rlqA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wmy | INTELECTIN-1 (Homo sapiens) |
no annotation | 5 | ILE A 149GLY A 148THR A 171LEU A 183PHE A 238 | None | 0.94A | 3t3rA-4wmyA:undetectable | 3t3rA-4wmyA:18.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y1y | GALECTIN-1 (Homo sapiens) |
PF00337(Gal-bind_lectin) | 5 | VAL A 98PHE A 106PHE A 30LEU A 100PHE A 79 | CSO A 88 ( 4.1A)CSO A 60 ( 3.8A)NoneNoneNone | 1.05A | 3t3rA-4y1yA:undetectable | 3t3rA-4y1yA:16.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z7r | COENZYME PQQSYNTHESIS PROTEIN B (Methylobacteriumextorquens) |
PF12706(Lactamase_B_2) | 5 | PHE A 106VAL A 84PHE A 124GLY A 96LEU A 86 | None | 1.17A | 3t3rA-4z7rA:undetectable | 3t3rA-4z7rA:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zdk | CTP SYNTHASE (Mycobacteriumtuberculosis) |
PF00117(GATase)PF06418(CTP_synth_N) | 5 | VAL A 295PHE A 329PHE A 85ILE A 256LEU A 291 | NoneNoneNoneACP A 602 (-4.7A)None | 1.13A | 3t3rA-4zdkA:undetectable | 3t3rA-4zdkA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aw4 | NA+,K+-ATPASE BETASUBUNIT (Squalusacanthias) |
PF00287(Na_K-ATPase) | 5 | PHE B 187ASN B 284ILE B 285GLY B 282LEU B 242 | None | 1.03A | 3t3rA-5aw4B:undetectable | 3t3rA-5aw4B:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bqk | ICP27 (Humanalphaherpesvirus1) |
PF05459(Herpes_UL69) | 6 | VAL A 429PHE A 430ILE A 475GLY A 471LEU A 390PHE A 349 | None | 1.44A | 3t3rA-5bqkA:undetectable | 3t3rA-5bqkA:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d1p | ATP-DEPENDENT RNALIGASE (Methanothermobacterthermautotrophicus) |
PF09414(RNA_ligase) | 6 | PHE A 172VAL A 174PHE A 140ILE A 105LEU A 195PHE A 139 | None | 1.44A | 3t3rA-5d1pA:undetectable | 3t3rA-5d1pA:21.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5e0e | CYTOCHROME P450FAMILY 2 SUBFAMILY B (Neotoma lepida) |
PF00067(p450) | 5 | PHE A 108VAL A 114PHE A 115GLY A 299THR A 302 | NoneHEM A 501 (-3.5A)NoneHEM A 501 (-3.5A)CPZ A 502 ( 4.0A) | 0.93A | 3t3rA-5e0eA:51.5 | 3t3rA-5e0eA:55.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f4c | PUTATIVE CYTOPLASMICPROTEIN (Salmonellaenterica) |
no annotation | 5 | PHE A 25VAL A 42PHE A 55ILE A 53LEU A 38 | None | 1.16A | 3t3rA-5f4cA:undetectable | 3t3rA-5f4cA:11.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fg0 | E3 UBIQUITIN-PROTEINLIGASE LISTERIN (Saccharomycescerevisiae) |
no annotation | 5 | PHE A 132PHE A 51ILE A 94LEU A 117PHE A 87 | None | 1.13A | 3t3rA-5fg0A:undetectable | 3t3rA-5fg0A:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fw4 | DYE-DECOLORIZINGPEROXIDASE TFU_3078 (Thermobifidafusca) |
PF04261(Dyp_perox) | 5 | PHE A 336VAL A 239GLY A 346LEU A 128PHE A 131 | HEM A 401 ( 4.0A)NoneNoneNoneNone | 0.78A | 3t3rA-5fw4A:undetectable | 3t3rA-5fw4A:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gam | PRE-MRNA-SPLICINGFACTOR 8 (Saccharomycescerevisiae) |
PF08082(PRO8NT)PF08083(PROCN) | 5 | PHE A 336PHE A 352PHE A 331ILE A 346GLY A 348 | None G U 104 ( 4.6A)NoneNoneNone | 1.11A | 3t3rA-5gamA:undetectable | 3t3rA-5gamA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h53 | SKELETAL MUSCLEMYOSIN HEAVY CHAINMYHC-EO/IIL (Oryctolaguscuniculus) |
PF00063(Myosin_head)PF02736(Myosin_N) | 5 | PHE A 254PHE A 196ASN A 172ILE A 459GLY A 460 | None | 0.84A | 3t3rA-5h53A:undetectable | 3t3rA-5h53A:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ik8 | LAMININ SUBUNITALPHA-2 (Mus musculus) |
PF00054(Laminin_G_1)PF02210(Laminin_G_2) | 5 | VAL A3024PHE A3080ILE A3084THR A2966LEU A2993 | None | 1.10A | 3t3rA-5ik8A:undetectable | 3t3rA-5ik8A:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ikg | DYE-DECOLORIZINGPEROXIDASE (Auriculariaauricula-judae) |
PF04261(Dyp_perox) | 5 | PHE A 27ASN A 30ILE A 29THR A 71LEU A 146 | None | 1.08A | 3t3rA-5ikgA:undetectable | 3t3rA-5ikgA:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kju | SHIKIMATEO-HYDROXYCINNAMOYLTRANSFERASE (Arabidopsisthaliana) |
PF02458(Transferase) | 5 | PHE A 388VAL A 39PHE A 41GLY A 393LEU A 117 | None | 1.16A | 3t3rA-5kjuA:undetectable | 3t3rA-5kjuA:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kjv | HYDROXYCINNAMOYLTRANSFERASE (Plectranthusscutellarioides) |
PF02458(Transferase) | 5 | PHE A 382VAL A 39PHE A 41GLY A 387LEU A 117 | None | 1.11A | 3t3rA-5kjvA:undetectable | 3t3rA-5kjvA:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ktg | GREEN FLUORESCENTPROTEIN, BCL-2HOMOLOGOUSANTAGONIST/KILLER (Aequoreavictoria;Mus musculus) |
PF00452(Bcl-2)PF01353(GFP) | 5 | PHE A 71VAL A 112ASN A 121ILE A 14PHE A 8 | NoneNoneCR2 A 66 ( 4.1A)NoneNone | 1.17A | 3t3rA-5ktgA:undetectable | 3t3rA-5ktgA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lp4 | PENICILLIN-BINDINGPROTEIN 2 (PBP2) (Helicobacterpylori) |
PF00905(Transpeptidase)PF03717(PBP_dimer) | 5 | VAL A 317PHE A 321ILE A 432GLY A 433LEU A 383 | None | 0.77A | 3t3rA-5lp4A:undetectable | 3t3rA-5lp4A:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5map | DTPA (Streptomyceslividans) |
PF04261(Dyp_perox) | 5 | PHE A 390VAL A 290GLY A 400LEU A 177PHE A 180 | HEM A 901 (-3.8A)NoneNoneNoneNone | 0.76A | 3t3rA-5mapA:undetectable | 3t3rA-5mapA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mze | 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE (Mus musculus) |
no annotation | 5 | PHE A 72PHE A 137ILE A 85GLY A 68LEU A 150 | 8DG A 204 (-3.7A)NoneNoneNoneNone | 1.03A | 3t3rA-5mzeA:undetectable | 3t3rA-5mzeA:10.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n2g | DNA POLYMERASE (Vaccinia virus) |
no annotation | 5 | PHE A 560PHE A 722ILE A 690GLY A 691PHE A 784 | None | 0.91A | 3t3rA-5n2gA:undetectable | 3t3rA-5n2gA:8.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nr1 | FTSZ-BINDING PROTEINFZLA (Caulobactervibrioides) |
PF00043(GST_C)PF13417(GST_N_3) | 5 | PHE A 104PHE A 108ILE A 150GLY A 148LEU A 143 | None | 1.04A | 3t3rA-5nr1A:undetectable | 3t3rA-5nr1A:18.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o7h | CRISPR-ASSOCIATEDPROTEIN, CSY4 FAMILY (Shewanellaputrefaciens) |
PF09618(Cas_Csy4) | 5 | PHE B 155VAL B 97PHE B 157PHE B 25GLY B 173 | None | 0.98A | 3t3rA-5o7hB:undetectable | 3t3rA-5o7hB:16.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oq3 | CWP19 (Clostridioidesdifficile) |
no annotation | 6 | PHE A 194VAL A 227PHE A 198ILE A 176LEU A 231PHE A 247 | None | 1.49A | 3t3rA-5oq3A:undetectable | 3t3rA-5oq3A:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t2h | I-ONUI_E-HTCRA (syntheticconstruct) |
PF00961(LAGLIDADG_1) | 5 | VAL A 252PHE A 253PHE A 237GLY A 220LEU A 171 | None | 0.99A | 3t3rA-5t2hA:undetectable | 3t3rA-5t2hA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t8d | I-ONUI_E-VHIVINT_V2 (syntheticconstruct) |
PF00961(LAGLIDADG_1) | 5 | VAL A 252PHE A 253PHE A 237GLY A 220LEU A 171 | None | 0.97A | 3t3rA-5t8dA:undetectable | 3t3rA-5t8dA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u2g | PENICILLIN-BINDINGPROTEIN 1A (Haemophilusinfluenzae) |
PF00905(Transpeptidase)PF00912(Transgly)PF17092(PCB_OB) | 5 | VAL A 69PHE A 82ASN A 165GLY A 175LEU A 188 | None | 1.12A | 3t3rA-5u2gA:undetectable | 3t3rA-5u2gA:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u84 | ACID CERAMIDASE (Balaenopteraacutorostrata) |
no annotation | 5 | PHE A 136ILE A 237GLY A 235LEU A 167PHE A 87 | None | 1.13A | 3t3rA-5u84A:undetectable | 3t3rA-5u84A:10.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uc5 | CHS2 CHALCONESYNTHASE (Malus domestica) |
no annotation | 5 | VAL A 271PHE A 215GLY A 305LEU A 267PHE A 265 | None | 1.03A | 3t3rA-5uc5A:undetectable | 3t3rA-5uc5A:10.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ugf | PURINE NUCLEOSIDEPHOSPHORYLASE (Homo sapiens) |
PF01048(PNP_UDP_1) | 5 | VAL A 102PHE A 103ILE A 53LEU A 106PHE A 70 | None | 1.06A | 3t3rA-5ugfA:undetectable | 3t3rA-5ugfA:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uqj | U6 SNRNAPHOSPHODIESTERASE (Saccharomycescerevisiae) |
PF09749(HVSL) | 5 | PHE A 204PHE A 289ILE A 276LEU A 169PHE A 167 | None | 1.05A | 3t3rA-5uqjA:undetectable | 3t3rA-5uqjA:17.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x7s | GLYCOSIDE HYDROLASEFAMILY 31ALPHA-GLUCOSIDASE (Paenibacillussp. 598K) |
PF01055(Glyco_hydro_31)PF16338(DUF4968)PF16990(CBM_35)PF17137(DUF5110) | 5 | PHE A1135VAL A1275ILE A1190GLY A1259LEU A1130 | None | 1.16A | 3t3rA-5x7sA:undetectable | 3t3rA-5x7sA:16.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xsy | SODIUM CHANNELPROTEIN (Electrophoruselectricus) |
PF00520(Ion_trans)PF06512(Na_trans_assoc) | 5 | PHE A 785ASN A1257ILE A1260GLY A1261LEU A 790 | None | 1.05A | 3t3rA-5xsyA:undetectable | 3t3rA-5xsyA:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6anz | UNCHARACTERIZEDPROTEIN (Neisseriagonorrhoeae) |
no annotation | 5 | PHE A 12PHE A 36ILE A 22GLY A 9PHE A 42 | None | 1.10A | 3t3rA-6anzA:undetectable | 3t3rA-6anzA:15.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ay4 | CYP51, STEROL14ALPHA-DEMETHYLASE (Naegleriafowleri) |
no annotation | 5 | VAL A 135PHE A 144GLY A 432LEU A 186PHE A 147 | NoneNoneHEM A 501 ( 3.9A)NoneNone | 1.13A | 3t3rA-6ay4A:32.2 | 3t3rA-6ay4A:26.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b3y | DENNDOMAIN-CONTAININGPROTEIN 3 (Mus musculus) |
no annotation | 5 | PHE A 774PHE A 771PHE A 735ILE A 744THR A 914 | None | 1.15A | 3t3rA-6b3yA:undetectable | 3t3rA-6b3yA:11.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ekt | P-47 PROTEIN (Clostridiumbotulinum) |
no annotation | 5 | PHE A 68ASN A 106ILE A 88LEU A 109PHE A 166 | None | 1.16A | 3t3rA-6ektA:undetectable | 3t3rA-6ektA:21.91 |