SIMILAR PATTERNS OF AMINO ACIDS FOR 3SVP_B_H4BB760_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c4k | PROTEIN (ORNITHINEDECARBOXYLASE) (Lactobacillussp. 30A) |
PF01276(OKR_DC_1)PF03709(OKR_DC_1_N)PF03711(OKR_DC_1_C) | 4 | TRP A 673PHE A 681GLU A 649VAL A 667 | None | 1.30A | 3svpA-1c4kA:0.03svpB-1c4kA:0.0 | 3svpA-1c4kA:19.073svpB-1c4kA:19.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dvk | PRP18 (Saccharomycescerevisiae) |
PF02840(Prp18) | 4 | TRP A 242PHE A 239GLU A 241ARG A 123 | None | 1.47A | 3svpA-1dvkA:1.73svpB-1dvkA:1.5 | 3svpA-1dvkA:17.183svpB-1dvkA:17.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1flg | PROTEIN(QUINOPROTEINETHANOLDEHYDROGENASE) (Pseudomonasaeruginosa) |
PF01011(PQQ)PF13360(PQQ_2) | 4 | PHE A 501GLU A 519VAL A 41TRP A 521 | None | 1.29A | 3svpA-1flgA:undetectable3svpB-1flgA:0.0 | 3svpA-1flgA:19.673svpB-1flgA:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kh2 | ARGININOSUCCINATESYNTHETASE (Thermusthermophilus) |
PF00764(Arginosuc_synth) | 4 | PHE A 220GLU A 222ARG A 282VAL A 226 | None | 1.35A | 3svpA-1kh2A:0.03svpB-1kh2A:0.1 | 3svpA-1kh2A:22.653svpB-1kh2A:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mhz | METHANEMONOOXYGENASEHYDROXYLASE (Methylosinustrichosporium) |
PF02332(Phenol_Hydrox) | 4 | PHE D 35GLU D 132VAL D 28TRP D 31 | None | 1.39A | 3svpA-1mhzD:0.03svpB-1mhzD:0.0 | 3svpA-1mhzD:20.853svpB-1mhzD:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mzb | FERRIC UPTAKEREGULATION PROTEIN (Pseudomonasaeruginosa) |
PF01475(FUR) | 4 | PHE A 79GLU A 36ARG A 69VAL A 54 | None | 1.08A | 3svpA-1mzbA:0.23svpB-1mzbA:0.5 | 3svpA-1mzbA:16.593svpB-1mzbA:16.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vmk | PURINE NUCLEOSIDEPHOSPHORYLASE (Thermotogamaritima) |
PF01048(PNP_UDP_1) | 4 | TRP A 162PHE A 265GLU A 161VAL A 221 | None | 1.46A | 3svpA-1vmkA:undetectable3svpB-1vmkA:0.0 | 3svpA-1vmkA:21.483svpB-1vmkA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wql | ETHYLBENZENEDIOXYGENASE SMALLSUBUNIT (Pseudomonasfluorescens) |
PF00866(Ring_hydroxyl_B) | 4 | PHE B 163GLU B 26ARG B 156VAL B 128 | None | 1.20A | 3svpA-1wqlB:0.03svpB-1wqlB:0.0 | 3svpA-1wqlB:19.793svpB-1wqlB:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b39 | C3 (Bos taurus) |
PF00207(A2M)PF01759(NTR)PF01821(ANATO)PF01835(A2M_N)PF07677(A2M_recep)PF07678(A2M_comp)PF07703(A2M_N_2)PF10569(Thiol-ester_cl) | 4 | PHE A 722GLU A 693ARG A 708VAL A1424 | None | 1.02A | 3svpA-2b39A:0.03svpB-2b39A:0.0 | 3svpA-2b39A:13.583svpB-2b39A:13.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b4x | ANTITHROMBIN-III (Homo sapiens) |
PF00079(Serpin) | 4 | TRP I 225PHE I 274GLU I 378VAL I 375 | None | 1.48A | 3svpA-2b4xI:undetectable3svpB-2b4xI:undetectable | 3svpA-2b4xI:22.013svpB-2b4xI:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fja | ADENYLYLSULFATEREDUCTASE, SUBUNIT AADENYLYLSULFATEREDUCTASE, SUBUNIT B (Archaeoglobusfulgidus) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C)PF12139(APS-reductase_C)PF13187(Fer4_9) | 4 | TRP B 788GLU A 360ARG A 62VAL A 367 | None | 1.33A | 3svpA-2fjaB:undetectable3svpB-2fjaB:undetectable | 3svpA-2fjaB:18.253svpB-2fjaB:18.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i9u | CYTOSINE/GUANINEDEAMINASE RELATEDPROTEIN (Clostridiumacetobutylicum) |
PF01979(Amidohydro_1) | 4 | PHE A 99GLU A 101ARG A 202TRP A 93 | NoneNoneGUN A 503 (-3.7A)None | 1.40A | 3svpA-2i9uA:undetectable3svpB-2i9uA:0.4 | 3svpA-2i9uA:20.973svpB-2i9uA:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2noz | N-GLYCOSYLASE/DNALYASE (Homo sapiens) |
PF00730(HhH-GPD)PF07934(OGG_N) | 4 | PHE A 303GLU A 298VAL A 267TRP A 272 | None | 1.14A | 3svpA-2nozA:undetectable3svpB-2nozA:undetectable | 3svpA-2nozA:22.303svpB-2nozA:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vy0 | ENDO-BETA-1,3-GLUCANASE (Pyrococcusfuriosus) |
PF00722(Glyco_hydro_16) | 4 | TRP A 252PHE A 254GLU A 251VAL A 245 | NoneNoneMRD A1301 (-4.3A)None | 1.43A | 3svpA-2vy0A:undetectable3svpB-2vy0A:undetectable | 3svpA-2vy0A:20.003svpB-2vy0A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w4o | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE TYPE IV (Homo sapiens) |
PF00069(Pkinase) | 4 | TRP A 266PHE A 261ARG A 278VAL A 269 | None | 1.42A | 3svpA-2w4oA:1.43svpB-2w4oA:undetectable | 3svpA-2w4oA:20.263svpB-2w4oA:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xhy | 6-PHOSPHO-BETA-GLUCOSIDASE BGLA (Escherichiacoli) |
PF00232(Glyco_hydro_1) | 4 | PHE A 98GLU A 108ARG A 159VAL A 164 | None | 1.46A | 3svpA-2xhyA:0.23svpB-2xhyA:undetectable | 3svpA-2xhyA:20.633svpB-2xhyA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xvg | ALPHA XYLOSIDASE (Cellvibriojaponicus) |
PF01055(Glyco_hydro_31)PF16338(DUF4968)PF17137(DUF5110) | 4 | PHE A 698GLU A 722ARG A 697VAL A 717 | None | 1.31A | 3svpA-2xvgA:0.53svpB-2xvgA:undetectable | 3svpA-2xvgA:19.683svpB-2xvgA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ywb | GMP SYNTHASE[GLUTAMINE-HYDROLYZING] (Thermusthermophilus) |
PF00117(GATase)PF00958(GMP_synt_C) | 4 | PHE A 309GLU A 305ARG A 211VAL A 239 | None | 1.30A | 3svpA-2ywbA:undetectable3svpB-2ywbA:undetectable | 3svpA-2ywbA:21.543svpB-2ywbA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z11 | RIBOSOMAL-PROTEIN-ALANINEACETYLTRANSFERASE (Thermusthermophilus) |
PF13302(Acetyltransf_3) | 4 | TRP A 66PHE A 4GLU A 6VAL A 64 | None | 1.41A | 3svpA-2z11A:undetectable3svpB-2z11A:undetectable | 3svpA-2z11A:17.583svpB-2z11A:17.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b7f | GLYCOSYL HYDROLASE,BNR REPEAT (Cupriaviduspinatubonensis) |
no annotation | 4 | TRP A 374GLU A 372VAL A 314TRP A 293 | NoneEDO A 404 ( 3.8A)NoneNone | 1.44A | 3svpA-3b7fA:undetectable3svpB-3b7fA:undetectable | 3svpA-3b7fA:20.873svpB-3b7fA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bit | FACT COMPLEX SUBUNITSPT16 (Saccharomycescerevisiae) |
PF00557(Peptidase_M24)PF14826(FACT-Spt16_Nlob) | 4 | TRP A 147PHE A 117ARG A 105VAL A 35 | None | 1.50A | 3svpA-3bitA:undetectable3svpB-3bitA:undetectable | 3svpA-3bitA:23.513svpB-3bitA:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ddl | XANTHORHODOPSIN (Salinibacterruber) |
PF01036(Bac_rhodopsin) | 4 | TRP A 70PHE A 88GLU A 71VAL A 16 | None | 1.48A | 3svpA-3ddlA:undetectable3svpB-3ddlA:undetectable | 3svpA-3ddlA:20.143svpB-3ddlA:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gyx | ADENYLYLSULFATEREDUCTASE (Desulfovibriogigas) |
PF00890(FAD_binding_2)PF12139(APS-reductase_C)PF13187(Fer4_9) | 4 | TRP B 88GLU A 380ARG A 66VAL A 387 | None | 1.25A | 3svpA-3gyxB:undetectable3svpB-3gyxB:undetectable | 3svpA-3gyxB:16.673svpB-3gyxB:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ma6 | CALMODULIN-DOMAINPROTEIN KINASE 1 (Toxoplasmagondii) |
PF00069(Pkinase) | 4 | TRP A 257PHE A 252ARG A 269VAL A 260 | None | 1.43A | 3svpA-3ma6A:undetectable3svpB-3ma6A:undetectable | 3svpA-3ma6A:21.553svpB-3ma6A:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n3k | UBIQUITINCARBOXYL-TERMINALHYDROLASE 8 (Homo sapiens) |
PF00443(UCH) | 4 | TRP A1001PHE A 946GLU A 908ARG A 944 | None | 1.45A | 3svpA-3n3kA:undetectable3svpB-3n3kA:undetectable | 3svpA-3n3kA:19.833svpB-3n3kA:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ner | CYTOCHROME B5 TYPE B (Homo sapiens) |
PF00173(Cyt-b5) | 4 | PHE A 58GLU A 56ARG A 68VAL A 61 | HEM A 201 (-4.7A)NoneNoneHEM A 201 (-4.5A) | 1.46A | 3svpA-3nerA:undetectable3svpB-3nerA:undetectable | 3svpA-3nerA:14.933svpB-3nerA:14.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3owc | PROBABLEACETYLTRANSFERASE (Pseudomonasaeruginosa) |
PF00583(Acetyltransf_1) | 4 | PHE A 121GLU A 119ARG A 175VAL A 92 | None | 1.23A | 3svpA-3owcA:undetectable3svpB-3owcA:1.6 | 3svpA-3owcA:16.473svpB-3owcA:16.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rjy | ENDOGLUCANASEFNCEL5A (Fervidobacteriumnodosum) |
PF00150(Cellulase) | 4 | TRP A 146PHE A 162GLU A 187VAL A 149 | None | 1.27A | 3svpA-3rjyA:1.43svpB-3rjyA:1.4 | 3svpA-3rjyA:21.273svpB-3rjyA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ti8 | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 4 | PHE A 305GLU A 265VAL A 240TRP A 239 | None | 1.34A | 3svpA-3ti8A:undetectable3svpB-3ti8A:undetectable | 3svpA-3ti8A:22.643svpB-3ti8A:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uxm | THYMIDYLATE KINASE (Pseudomonasaeruginosa) |
PF02223(Thymidylate_kin) | 4 | PHE A 162GLU A 156ARG A 109VAL A 166 | None MG A 213 (-3.2A)NoneNone | 1.32A | 3svpA-3uxmA:0.83svpB-3uxmA:undetectable | 3svpA-3uxmA:20.293svpB-3uxmA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bgd | PRE-MRNA-SPLICINGFACTOR 8 (Saccharomycescerevisiae) |
PF08084(PROCT) | 4 | TRP C2314PHE C2329GLU C2310VAL C2274 | None | 1.31A | 3svpA-4bgdC:undetectable3svpB-4bgdC:undetectable | 3svpA-4bgdC:20.993svpB-4bgdC:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d8o | ANKYRIN-2 (Homo sapiens) |
PF00531(Death)PF00791(ZU5) | 4 | PHE A1118GLU A1032ARG A1065VAL A1046 | None | 1.40A | 3svpA-4d8oA:undetectable3svpB-4d8oA:undetectable | 3svpA-4d8oA:19.443svpB-4d8oA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l37 | ARYLPHORIN (Bombyx mori) |
PF00372(Hemocyanin_M)PF03722(Hemocyanin_N)PF03723(Hemocyanin_C) | 4 | PHE B 327GLU B 424VAL B 351TRP B 355 | None | 1.09A | 3svpA-4l37B:undetectable3svpB-4l37B:undetectable | 3svpA-4l37B:20.693svpB-4l37B:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xj6 | VC0179-LIKE PROTEIN (Escherichiacoli) |
no annotation | 4 | PHE A 264GLU A 266ARG A 276VAL A 305 | None | 1.22A | 3svpA-4xj6A:undetectable3svpB-4xj6A:undetectable | 3svpA-4xj6A:21.063svpB-4xj6A:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xj6 | VC0179-LIKE PROTEIN (Escherichiacoli) |
no annotation | 4 | TRP A 263PHE A 264GLU A 266VAL A 305 | None | 1.10A | 3svpA-4xj6A:undetectable3svpB-4xj6A:undetectable | 3svpA-4xj6A:21.063svpB-4xj6A:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ylr | TUBULINPOLYGLUTAMYLASETTLL7 (Homo sapiens) |
PF03133(TTL) | 4 | PHE A 277GLU A 279VAL A 288TRP A 292 | None | 1.42A | 3svpA-4ylrA:undetectable3svpB-4ylrA:undetectable | 3svpA-4ylrA:22.813svpB-4ylrA:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c6g | AGR133CPSISTER CHROMATIDCOHESION PROTEIN 2 (Eremotheciumgossypii) |
PF10345(Cohesin_load)no annotation | 4 | TRP A 401PHE A 397GLU A 402VAL B 28 | None | 1.50A | 3svpA-5c6gA:3.53svpB-5c6gA:undetectable | 3svpA-5c6gA:21.863svpB-5c6gA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fjn | L-AMINO ACIDDEAMINASE (Cosenzaeamyxofaciens) |
PF01266(DAO) | 4 | GLU A 418ARG A 316VAL A 438TRP A 439 | NoneBE2 A1476 (-4.0A)BE2 A1476 ( 4.3A)BE2 A1476 ( 3.7A) | 1.37A | 3svpA-5fjnA:undetectable3svpB-5fjnA:undetectable | 3svpA-5fjnA:23.273svpB-5fjnA:23.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kqi | CATALASE-PEROXIDASE (Burkholderiapseudomallei) |
PF00141(peroxidase) | 4 | TRP A 736PHE A 732GLU A 560VAL A 481 | None | 1.50A | 3svpA-5kqiA:undetectable3svpB-5kqiA:undetectable | 3svpA-5kqiA:20.853svpB-5kqiA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m8t | 5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACIDOXIDASE (Homo sapiens) |
PF00264(Tyrosinase) | 4 | TRP A 414PHE A 411GLU A 413ARG A 225 | None | 1.07A | 3svpA-5m8tA:undetectable3svpB-5m8tA:undetectable | 3svpA-5m8tA:20.003svpB-5m8tA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xgp | SECRETED XWNT8INHIBITOR SIZZLED (Xenopus laevis) |
PF01392(Fz) | 4 | PHE A 180GLU A 222VAL A 254TRP A 224 | None | 0.88A | 3svpA-5xgpA:undetectable3svpB-5xgpA:undetectable | 3svpA-5xgpA:19.673svpB-5xgpA:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bk1 | UDP-GLYCOSYLTRANSFERASE 79 (Oryza sativa) |
no annotation | 4 | GLU A 322ARG A 331VAL A 317TRP A 316 | NoneNoneUDP A 501 ( 4.8A)None | 1.25A | 3svpA-6bk1A:undetectable3svpB-6bk1A:undetectable | 3svpA-6bk1A:13.483svpB-6bk1A:13.48 |