SIMILAR PATTERNS OF AMINO ACIDS FOR 3SUF_B_SUEB1201_3

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a7j PHOSPHORIBULOKINASE

(Rhodobacter
sphaeroides) 		PF00485
(PRK) 		4 SER A 229
ARG A 208
PRO A 156
VAL A 157
 None
 1.13A 3sufC-1a7jA:
0.0		 3sufC-1a7jA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aqk FAB B7-15A2

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 SER H  85
ARG H  87
PRO H  88
VAL H 121
 None
 1.12A 3sufC-1aqkH:
undetectable		 3sufC-1aqkH:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b2w PROTEIN (ANTIBODY
(HEAVY CHAIN))

(Homo sapiens;
Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 SER H  85
ARG H  87
PRO H  88
VAL H 115
 None
 1.29A 3sufC-1b2wH:
0.0		 3sufC-1b2wH:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bg5 FUSION PROTEIN OF
ALPHA-NA,K-ATPASE
WITH GLUTATHIONE
S-TRANSFERASE

(Rattus
norvegicus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 SER A 226
ARG A 224
PRO A 223
VAL A 222
 None
 1.01A 3sufC-1bg5A:
undetectable		 3sufC-1bg5A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bhg BETA-GLUCURONIDASE

(Homo sapiens) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		4 SER A 447
PRO A 387
TYR A 388
VAL A 433
 None
 1.15A 3sufC-1bhgA:
0.5		 3sufC-1bhgA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)

(Lactobacillus
sp. 30A) 		PF01276
(OKR_DC_1)
PF03709
(OKR_DC_1_N)
PF03711
(OKR_DC_1_C) 		4 SER A 534
PRO A 516
TYR A 603
VAL A 515
 None
 1.31A 3sufC-1c4kA:
undetectable		 3sufC-1c4kA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ciy CRYIA(A)

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		4 SER A 438
ARG A 448
TYR A 315
VAL A 272
 None
 1.30A 3sufC-1ciyA:
0.1		 3sufC-1ciyA:
15.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1cu1 PROTEIN
(PROTEASE/HELICASE
NS3)

(Hepacivirus C) 		PF02907
(Peptidase_S29)
PF07652
(Flavi_DEAD) 		5 SER A 128
ARG A 130
PRO A 131
TYR A 134
VAL A 163
 None
 0.61A 3sufC-1cu1A:
34.0		 3sufC-1cu1A:
81.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i8n ANTI-PLATELET
PROTEIN

(Haementeria
officinalis) 		no annotation 4 SER A  48
ARG A  50
PRO A  51
VAL A 117
 None
 1.43A 3sufC-1i8nA:
undetectable		 3sufC-1i8nA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j2b ARCHAEOSINE
TRNA-GUANINE
TRANSGLYCOSYLASE

(Pyrococcus
horikoshii) 		PF01472
(PUA)
PF01702
(TGT)
PF14809
(TGT_C1)
PF14810
(TGT_C2) 		4 SER A 185
ARG A 224
PRO A 225
VAL A 226
 None
 1.29A 3sufC-1j2bA:
0.0		 3sufC-1j2bA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kxh ALPHA-AMYLASE

(Pseudoalteromonas
haloplanktis) 		PF00128
(Alpha-amylase)
PF02806
(Alpha-amylase_C) 		4 SER A  59
PRO A  52
TYR A  50
VAL A  53
 None
None
ACR  A 598 (-4.5A)
None
 1.25A 3sufC-1kxhA:
undetectable		 3sufC-1kxhA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lw7 TRANSCRIPTIONAL
REGULATOR NADR

(Haemophilus
influenzae) 		PF01467
(CTP_transf_like)
PF13521
(AAA_28) 		4 ARG A 117
PRO A  69
TYR A  68
VAL A  70
 None
 1.40A 3sufC-1lw7A:
undetectable		 3sufC-1lw7A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1md6 INTERLEUKIN 1
FAMILY, MEMBER 5
(DELTA)

(Mus musculus) 		PF00340
(IL1) 		4 SER A  42
PRO A  45
TYR A  88
VAL A  56
 None
 1.35A 3sufC-1md6A:
undetectable		 3sufC-1md6A:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ns3 NS3 PROTEASE

(Hepacivirus C) 		PF02907
(Peptidase_S29) 		4 SER A 128
ARG A 130
PRO A 131
VAL A 163
 None
 1.10A 3sufC-1ns3A:
29.8		 3sufC-1ns3A:
78.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qni NITROUS-OXIDE
REDUCTASE

(Marinobacter
hydrocarbonoclasticus) 		no annotation 4 SER A 201
PRO A 269
TYR A 204
VAL A 265
 None
 1.41A 3sufC-1qniA:
undetectable		 3sufC-1qniA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qnl ALIPHATIC AMIDASE
EXPRESSION-REGULATIN
G PROTEIN

(Pseudomonas
aeruginosa) 		PF13433
(Peripla_BP_5) 		4 SER A 235
PRO A 255
TYR A 256
VAL A 253
 None
 1.25A 3sufC-1qnlA:
undetectable		 3sufC-1qnlA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r1n FERRIC-IRON BINDING
PROTEIN

(Neisseria
gonorrhoeae) 		PF01547
(SBP_bac_1) 		4 SER A 228
ARG A 101
TYR A 195
VAL A 225
 None
None
CNB  A 400 (-4.8A)
None
 1.36A 3sufC-1r1nA:
undetectable		 3sufC-1r1nA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t3q QUINOLINE
2-OXIDOREDUCTASE
LARGE SUBUNIT

(Pseudomonas
putida) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 SER B 506
PRO B 249
TYR B  33
VAL B 248
 MCN  B4921 (-2.6A)
None
None
None
 1.30A 3sufC-1t3qB:
undetectable		 3sufC-1t3qB:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tpg T-PLASMINOGEN
ACTIVATOR F1-G

(Homo sapiens) 		PF00008
(EGF)
PF00039
(fn1) 		4 SER A  28
ARG A  30
PRO A  47
VAL A  48
 None
 1.43A 3sufC-1tpgA:
undetectable		 3sufC-1tpgA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vke CARBOXYMUCONOLACTONE
DECARBOXYLASE FAMILY
PROTEIN

(Thermotoga
maritima) 		PF02627
(CMD) 		4 SER A  33
ARG A  37
PRO A  38
VAL A  43
 None
 1.03A 3sufC-1vkeA:
undetectable		 3sufC-1vkeA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wfy RAP1/RAP2
INTERACTING PROTEIN
REGULATOR OF
G-PROTEIN SIGNALING
14

(Mus musculus) 		PF02196
(RBD) 		4 SER A  33
ARG A  16
PRO A  36
VAL A  75
 None
 1.39A 3sufC-1wfyA:
undetectable		 3sufC-1wfyA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wz2 LEUCYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1) 		4 SER A 147
ARG A 148
PRO A  77
VAL A 144
 None
 1.34A 3sufC-1wz2A:
undetectable		 3sufC-1wz2A:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bs9 BETA-XYLOSIDASE

(Geobacillus
stearothermophilus) 		PF01229
(Glyco_hydro_39) 		4 ARG A  95
PRO A  96
TYR A  50
VAL A  86
 None
 0.99A 3sufC-2bs9A:
undetectable		 3sufC-2bs9A:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c2g THREONINE SYNTHASE

(Arabidopsis
thaliana) 		PF00291
(PALP) 		4 SER A 364
ARG A 367
TYR A 301
VAL A 369
 None
 1.41A 3sufC-2c2gA:
undetectable		 3sufC-2c2gA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2doc NEURAL CELL ADHESION
MOLECULE 2

(Homo sapiens) 		PF00041
(fn3) 		4 SER A  37
PRO A  21
TYR A  22
VAL A  91
 None
 1.40A 3sufC-2docA:
undetectable		 3sufC-2docA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e4u METABOTROPIC
GLUTAMATE RECEPTOR 3

(Rattus
norvegicus) 		PF01094
(ANF_receptor)
PF07562
(NCD3G) 		4 SER A 175
PRO A 192
TYR A 196
VAL A 191
 None
 1.42A 3sufC-2e4uA:
undetectable		 3sufC-2e4uA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ftp HYDROXYMETHYLGLUTARY
L-COA LYASE

(Pseudomonas
aeruginosa) 		PF00682
(HMGL-like) 		4 SER A 120
ARG A 123
PRO A 126
VAL A 125
 None
 1.35A 3sufC-2ftpA:
undetectable		 3sufC-2ftpA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hz6 ENDOPLASMIC
RETICULUM TO NUCLEUS
SIGNALLING 1 ISOFORM
1 VARIANT

(Homo sapiens) 		PF13360
(PQQ_2) 		4 SER A  41
PRO A 225
TYR A 289
VAL A 226
 None
 1.36A 3sufC-2hz6A:
0.4		 3sufC-2hz6A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jll NEURAL CELL ADHESION
MOLECULE 2

(Homo sapiens) 		PF00041
(fn3)
PF07679
(I-set)
PF13927
(Ig_3) 		4 SER A 515
PRO A 499
TYR A 500
VAL A 569
 None
 1.19A 3sufC-2jllA:
undetectable		 3sufC-2jllA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vca ALPHA-N-ACETYLGLUCOS
AMINIDASE

(Clostridium
perfringens) 		PF00754
(F5_F8_type_C)
PF05089
(NAGLU)
PF12971
(NAGLU_N)
PF12972
(NAGLU_C) 		4 SER A 429
ARG A 416
PRO A 415
VAL A 414
 None
None
GOL  A1914 ( 4.6A)
GOL  A1914 (-4.2A)
 1.16A 3sufC-2vcaA:
undetectable		 3sufC-2vcaA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wjr PROBABLE
N-ACETYLNEURAMINIC
ACID OUTER MEMBRANE
CHANNEL PROTEIN NANC

(Escherichia
coli) 		PF06178
(KdgM) 		4 SER A  93
ARG A  72
PRO A  73
VAL A  90
 EPE  A1217 ( 4.7A)
EPE  A1217 (-3.7A)
None
None
 1.31A 3sufC-2wjrA:
undetectable		 3sufC-2wjrA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xyc NEURAL CELL ADHESION
MOLECULE 2

(Homo sapiens) 		PF00041
(fn3)
PF07679
(I-set)
PF13927
(Ig_3) 		4 SER A 515
PRO A 499
TYR A 500
VAL A 569
 None
 1.23A 3sufC-2xycA:
undetectable		 3sufC-2xycA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yik ENDOGLUCANASE

(Ruminiclostridium
thermocellum) 		PF00759
(Glyco_hydro_9) 		4 SER A 446
PRO A 450
TYR A 449
VAL A 476
 None
 1.41A 3sufC-2yikA:
undetectable		 3sufC-2yikA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z13 EF-HAND
DOMAIN-CONTAINING
FAMILY MEMBER C2

(Homo sapiens) 		PF06565
(DUF1126) 		4 SER A  17
PRO A  45
TYR A  44
VAL A  86
 None
 1.30A 3sufC-2z13A:
undetectable		 3sufC-2z13A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a0f XYLOGLUCANASE

(Geotrichum sp.
M128) 		no annotation 4 SER A 653
PRO A 631
TYR A 599
VAL A 632
 None
 1.40A 3sufC-3a0fA:
undetectable		 3sufC-3a0fA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3af5 PUTATIVE
UNCHARACTERIZED
PROTEIN PH1404

(Pyrococcus
horikoshii) 		PF07521
(RMMBL)
PF10996
(Beta-Casp)
PF16661
(Lactamase_B_6)
PF17214
(KH_7) 		4 SER A  71
ARG A  73
PRO A  74
VAL A  46
 None
 1.01A 3sufC-3af5A:
undetectable		 3sufC-3af5A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3av3 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE

(Geobacillus
kaustophilus) 		PF00551
(Formyl_trans_N) 		4 SER A   9
ARG A  38
PRO A  39
VAL A  56
 None
 1.39A 3sufC-3av3A:
undetectable		 3sufC-3av3A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cfi NANOBODY NBEPSIJ_11

(Lama glama) 		PF07686
(V-set) 		4 SER C  84
ARG C  86
PRO C  87
VAL C 115
 None
 1.36A 3sufC-3cfiC:
undetectable		 3sufC-3cfiC:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fve DIAMINOPIMELATE
EPIMERASE

(Mycobacterium
tuberculosis) 		PF01678
(DAP_epimerase) 		4 SER A 113
ARG A 118
PRO A 119
VAL A 110
 None
None
None
GOL  A 291 (-3.5A)
 1.33A 3sufC-3fveA:
undetectable		 3sufC-3fveA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fy6 INTEGRON CASSETTE
PROTEIN

(Vibrio cholerae) 		no annotation 4 SER A  10
PRO A  65
TYR A  64
VAL A 101
 None
 0.92A 3sufC-3fy6A:
undetectable		 3sufC-3fy6A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hxk SUGAR HYDROLASE

(Lactococcus
lactis) 		PF00326
(Peptidase_S9) 		4 SER A 156
PRO A 203
TYR A 205
VAL A 202
 None
 1.31A 3sufC-3hxkA:
undetectable		 3sufC-3hxkA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i04 CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT ALPHA

(Moorella
thermoacetica) 		PF03598
(CdhC) 		4 ARG M  66
PRO M  63
TYR M  61
VAL M  64
 None
 1.08A 3sufC-3i04M:
undetectable		 3sufC-3i04M:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jr3 NAD-DEPENDENT
DEACETYLASE

(Thermotoga
maritima) 		PF02146
(SIR2) 		4 SER A 153
PRO A 146
TYR A 131
VAL A 145
 None
 1.24A 3sufC-3jr3A:
undetectable		 3sufC-3jr3A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k2m MONOBODY HA4

(Homo sapiens) 		PF00041
(fn3) 		4 SER C  60
PRO C  56
TYR C  57
VAL C  55
 None
 1.26A 3sufC-3k2mC:
undetectable		 3sufC-3k2mC:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kez PUTATIVE SUGAR
BINDING PROTEIN

(Bacteroides
vulgatus) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 SER A  58
ARG A  64
TYR A  88
VAL A  66
 None
EDO  A   8 (-3.3A)
None
None
 1.33A 3sufC-3kezA:
undetectable		 3sufC-3kezA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l7z PROBABLE EXOSOME
COMPLEX RNA-BINDING
PROTEIN 1

(Sulfolobus
solfataricus) 		no annotation 4 SER C 136
PRO C 139
TYR C  96
VAL C 140
 None
 1.36A 3sufC-3l7zC:
undetectable		 3sufC-3l7zC:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mae 2-OXOISOVALERATE
DEHYDROGENASE E2
COMPONENT,
DIHYDROLIPOAMIDE
ACETYLTRANSFERASE

(Listeria
monocytogenes) 		PF00198
(2-oxoacid_dh) 		4 SER A 322
PRO A 292
TYR A 290
VAL A 293
 None
 1.39A 3sufC-3maeA:
undetectable		 3sufC-3maeA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pw3 AMINOPEPTIDASE C

(Parabacteroides
distasonis) 		PF03051
(Peptidase_C1_2) 		4 SER A 104
ARG A  92
TYR A  89
VAL A 153
 None
 1.39A 3sufC-3pw3A:
undetectable		 3sufC-3pw3A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3top MALTASE-GLUCOAMYLASE
, INTESTINAL

(Homo sapiens) 		PF00088
(Trefoil)
PF01055
(Glyco_hydro_31)
PF16863
(NtCtMGAM_N) 		4 SER A1515
PRO A1171
TYR A1172
VAL A1169
 None
 1.18A 3sufC-3topA:
undetectable		 3sufC-3topA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tr1 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Coxiella
burnetii) 		PF00275
(EPSP_synthase) 		4 SER A 119
ARG A 123
PRO A 124
VAL A 145
 None
PO4  A 440 (-2.9A)
PO4  A 443 (-4.4A)
None
 1.22A 3sufC-3tr1A:
undetectable		 3sufC-3tr1A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uet ALPHA-1,3/4-FUCOSIDA
SE

(Bifidobacterium
longum) 		PF01120
(Alpha_L_fucos) 		4 SER A 227
ARG A 212
PRO A 230
VAL A 275
 None
 1.34A 3sufC-3uetA:
undetectable		 3sufC-3uetA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3upu ATP-DEPENDENT DNA
HELICASE DDA

(Escherichia
virus T4) 		PF13604
(AAA_30) 		4 SER A 402
ARG A 433
TYR A 434
VAL A 436
 None
 0.98A 3sufC-3upuA:
undetectable		 3sufC-3upuA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vuo NTNHA

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07953
(Toxin_R_bind_N)
PF08470
(NTNH_C) 		4 SER A1045
ARG A 908
TYR A1012
VAL A 872
 None
 1.28A 3sufC-3vuoA:
undetectable		 3sufC-3vuoA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f92 U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02889
(Sec63) 		4 ARG B 858
PRO B 859
TYR B 861
VAL B 683
 None
 1.39A 3sufC-4f92B:
undetectable		 3sufC-4f92B:
8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fc2 POLY(ADP-RIBOSE)
GLYCOHYDROLASE

(Mus musculus) 		PF05028
(PARG_cat) 		4 SER A 466
ARG A 468
PRO A 469
VAL A 475
 SO4  A1001 (-3.0A)
SO4  A1001 (-3.1A)
None
None
 0.87A 3sufC-4fc2A:
undetectable		 3sufC-4fc2A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gnk 1-PHOSPHATIDYLINOSIT
OL 4,5-BISPHOSPHATE
PHOSPHODIESTERASE
BETA-3

(Homo sapiens) 		PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like) 		4 SER B 200
ARG B 169
PRO B 171
VAL B 172
 None
 1.30A 3sufC-4gnkB:
undetectable		 3sufC-4gnkB:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4grw NANOBODY 22E11

(Lama glama) 		PF07686
(V-set) 		4 SER H  85
ARG H  87
PRO H  88
VAL H 121
 None
 1.11A 3sufC-4grwH:
undetectable		 3sufC-4grwH:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hao PROBABLE INORGANIC
POLYPHOSPHATE/ATP-NA
D KINASE

(Yersinia pestis) 		PF01513
(NAD_kinase) 		4 SER A 123
PRO A 272
TYR A 275
VAL A 116
 None
 1.40A 3sufC-4haoA:
undetectable		 3sufC-4haoA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j7b POLO-LIKE KINASE

(Danio rerio) 		PF00659
(POLO_box) 		4 SER B 430
ARG B 432
TYR B 501
VAL B 425
 None
 1.38A 3sufC-4j7bB:
undetectable		 3sufC-4j7bB:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mni TRAP DICARBOXYLATE
TRANSPORTER-DCTP
SUBUNIT

(Polaromonas sp.
JS666) 		PF03480
(DctP) 		4 SER A 170
ARG A 168
TYR A 204
VAL A 184
 173  A 401 (-2.6A)
173  A 401 (-2.8A)
None
None
 1.28A 3sufC-4mniA:
undetectable		 3sufC-4mniA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n0i GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF01425
(Amidase) 		4 SER A 425
PRO A 430
TYR A 450
VAL A 447
 None
 1.41A 3sufC-4n0iA:
undetectable		 3sufC-4n0iA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n54 INOSITOL
DEHYDROGENASE

(Lactobacillus
casei) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 ARG A 290
PRO A 266
TYR A 247
VAL A 265
 None
None
2H3  A 402 (-4.5A)
None
 1.39A 3sufC-4n54A:
undetectable		 3sufC-4n54A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nqa LIVER X NUCLEAR
RECEPTOR BETA

(Homo sapiens) 		PF00104
(Hormone_recep)
PF00105
(zf-C4) 		4 SER B 380
ARG B 383
PRO B 384
VAL B 386
 None
 1.42A 3sufC-4nqaB:
undetectable		 3sufC-4nqaB:
18.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4nwk HCV NS3 1A PROTEASE

(Hepacivirus C) 		PF02907
(Peptidase_S29) 		4 ARG A 130
PRO A 131
TYR A 134
VAL A 163
 None
 0.71A 3sufC-4nwkA:
35.2		 3sufC-4nwkA:
99.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4nwk HCV NS3 1A PROTEASE

(Hepacivirus C) 		PF02907
(Peptidase_S29) 		4 SER A 128
PRO A 131
TYR A 134
VAL A 163
 None
 0.85A 3sufC-4nwkA:
35.2		 3sufC-4nwkA:
99.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nwv CAPSID PROTEIN

(Orsay virus) 		PF11729
(Capsid-VNN) 		4 SER A 366
PRO A 364
TYR A 381
VAL A 363
 None
 1.41A 3sufC-4nwvA:
undetectable		 3sufC-4nwvA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nww CAPSID PROTEIN

(Orsay virus) 		PF11729
(Capsid-VNN) 		4 SER A 366
PRO A 364
TYR A 381
VAL A 363
 None
 1.40A 3sufC-4nwwA:
undetectable		 3sufC-4nwwA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6x PHOSPHOLIPASE D
STSICTOX-BETAIC1

(Sicarius
terrosus) 		no annotation 4 SER A 227
PRO A 250
TYR A  22
VAL A 253
 None
 1.34A 3sufC-4q6xA:
undetectable		 3sufC-4q6xA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6x PHOSPHOLIPASE D
STSICTOX-BETAIC1

(Sicarius
terrosus) 		no annotation 4 SER A 227
PRO A 250
TYR A 249
VAL A 253
 None
 1.35A 3sufC-4q6xA:
undetectable		 3sufC-4q6xA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qww ACETYLCHOLINESTERASE

(Bungarus
fasciatus) 		PF00135
(COesterase) 		4 SER A  19
PRO A 102
TYR A 137
VAL A 101
 None
 1.23A 3sufC-4qwwA:
undetectable		 3sufC-4qwwA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r5z PUTATIVE
PHENYLALANINE
AMINOTRANSFERASE

(Mycobacterium
tuberculosis) 		PF00155
(Aminotran_1_2) 		4 SER A  29
ARG A 322
PRO A 323
VAL A 329
 SIN  A 401 (-2.7A)
SIN  A 401 (-3.0A)
None
None
 1.18A 3sufC-4r5zA:
undetectable		 3sufC-4r5zA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rm4 CYTOCHROME P450

(Bacillus
subtilis) 		PF00067
(p450) 		4 SER A 316
PRO A 287
TYR A 387
VAL A 288
 None
 1.42A 3sufC-4rm4A:
undetectable		 3sufC-4rm4A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ubd MONOCLONAL ANTIBODY
H CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 SER C  85
ARG C  87
PRO C  88
VAL C 124
 None
 1.12A 3sufC-4ubdC:
undetectable		 3sufC-4ubdC:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uml GANGLIOSIDE-INDUCED
DIFFERENTIATION-ASSO
CIATED PROTEIN 2

(Homo sapiens) 		PF01661
(Macro) 		4 SER A 147
PRO A 131
TYR A 176
VAL A 129
 None
 1.39A 3sufC-4umlA:
undetectable		 3sufC-4umlA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wik SPLICING FACTOR,
PROLINE- AND
GLUTAMINE-RICH

(Homo sapiens) 		PF00076
(RRM_1)
PF08075
(NOPS) 		4 SER A 379
ARG A 443
PRO A 444
VAL A 445
 None
 1.37A 3sufC-4wikA:
undetectable		 3sufC-4wikA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y9v PARTICLE-ASSOCIATED
LYASE

(Acinetobacter
virus AP22) 		no annotation 4 SER A 385
PRO A 416
TYR A 271
VAL A 415
 None
 1.41A 3sufC-4y9vA:
undetectable		 3sufC-4y9vA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yg3 OUTER CAPSID PROTEIN
VP4

(Rotavirus A) 		no annotation 4 SER A  87
ARG A 162
TYR A 137
VAL A  92
 SO4  A 303 (-4.9A)
SO4  A 303 ( 3.0A)
None
None
 1.40A 3sufC-4yg3A:
undetectable		 3sufC-4yg3A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zzq CELLULOSE
1,4-BETA-CELLOBIOSID
ASE

(Dictyostelium
discoideum) 		PF00840
(Glyco_hydro_7) 		4 SER A 411
PRO A 418
TYR A 417
VAL A  95
 None
 0.78A 3sufC-4zzqA:
undetectable		 3sufC-4zzqA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d6h CSUC

(Acinetobacter
baumannii) 		PF00345
(PapD_N) 		4 SER A 117
PRO A  10
TYR A   9
VAL A  21
 None
 1.36A 3sufC-5d6hA:
undetectable		 3sufC-5d6hA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5en6 SMU-1

(Caenorhabditis
elegans) 		no annotation 4 SER A 120
ARG A 124
PRO A 125
TYR A 126
 None
 1.41A 3sufC-5en6A:
undetectable		 3sufC-5en6A:
22.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5eqq NS3 PROTEASE

(Hepacivirus C) 		PF02907
(Peptidase_S29) 		4 SER A1128
ARG A1130
PRO A1131
VAL A1163
 None
 0.53A 3sufC-5eqqA:
33.9		 3sufC-5eqqA:
94.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fji BETA-GLUCOSIDASE

(Aspergillus
fumigatus) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 SER A  79
PRO A 712
TYR A 711
VAL A  60
 NAG  A1001 (-2.7A)
None
NAG  A1002 ( 4.3A)
None
 1.33A 3sufC-5fjiA:
undetectable		 3sufC-5fjiA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gq0 EPITHIOSPECIFIER
PROTEIN

(Arabidopsis
thaliana) 		no annotation 4 SER B 275
ARG B 242
TYR B 200
VAL B 244
 None
 1.16A 3sufC-5gq0B:
undetectable		 3sufC-5gq0B:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i5l BACTERIOPHYTOCHROME
PROTEIN

(Agrobacterium
fabrum) 		PF00360
(PHY)
PF01590
(GAF)
PF08446
(PAS_2) 		4 SER A 464
PRO A 461
TYR A 253
VAL A 453
 None
BLA  A 601 ( 4.6A)
BLA  A 601 (-4.4A)
None
 1.28A 3sufC-5i5lA:
undetectable		 3sufC-5i5lA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jtw COMPLEMENT C4-A

(Homo sapiens) 		PF00207
(A2M)
PF07678
(A2M_comp)
PF10569
(Thiol-ester_cl) 		4 SER B 893
ARG B 895
PRO B 896
VAL B 854
 None
 1.05A 3sufC-5jtwB:
undetectable		 3sufC-5jtwB:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ju6 BETA-GLUCOSIDASE

(Rasamsonia
emersonii) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 SER A  79
PRO A 704
TYR A 703
VAL A  60
 NAG  A 901 (-2.8A)
None
NAG  A 902 (-4.4A)
None
 1.35A 3sufC-5ju6A:
undetectable		 3sufC-5ju6A:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l9w ACETOPHENONE
CARBOXYLASE DELTA
SUBUNIT

(Aromatoleum
aromaticum) 		PF02538
(Hydantoinase_B) 		4 SER A 565
ARG A 567
PRO A 568
TYR A 569
 None
 1.30A 3sufC-5l9wA:
undetectable		 3sufC-5l9wA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l9w ACETOPHENONE
CARBOXYLASE DELTA
SUBUNIT

(Aromatoleum
aromaticum) 		PF02538
(Hydantoinase_B) 		4 SER A 565
ARG A 567
TYR A 569
VAL A 400
 None
 1.17A 3sufC-5l9wA:
undetectable		 3sufC-5l9wA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lbs BROADLY NEUTRALIZING
HUMAN ANTIBODY EDE1
C8

(Homo sapiens) 		PF07686
(V-set) 		4 SER H  82
ARG H  83
PRO H  84
VAL H 111
 None
 1.11A 3sufC-5lbsH:
undetectable		 3sufC-5lbsH:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lki TCDA1

(Photorhabdus
luminescens) 		PF03538
(VRP1) 		4 SER A1035
PRO A1041
TYR A1044
VAL A1840
 None
 1.34A 3sufC-5lkiA:
undetectable		 3sufC-5lkiA:
6.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m6p TYROCIDINE SYNTHASE
2

(Brevibacillus
parabrevis) 		no annotation 4 SER A3475
PRO A3419
TYR A3418
VAL A3390
 None
 1.34A 3sufC-5m6pA:
undetectable		 3sufC-5m6pA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mqs BETA-L-ARABINOBIOSID
ASE

(Bacteroides
thetaiotaomicron) 		PF13088
(BNR_2) 		4 SER A 367
ARG A 332
PRO A 370
VAL A 394
 None
PTR  A 372 ( 2.6A)
None
None
 1.38A 3sufC-5mqsA:
undetectable		 3sufC-5mqsA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mtz RIBONUCLEASE Z

(Saccharomyces
cerevisiae) 		PF13691
(Lactamase_B_4) 		4 SER A  98
ARG A 101
TYR A 102
VAL A 104
 None
 1.24A 3sufC-5mtzA:
undetectable		 3sufC-5mtzA:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mzv NANOBODY 22E11

(Lama glama) 		no annotation 4 SER D  85
ARG D  87
PRO D  88
VAL D 121
 None
 1.04A 3sufC-5mzvD:
undetectable		 3sufC-5mzvD:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w4b ADENOSYLHOMOCYSTEINA
SE

(Homo sapiens) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		4 SER A 154
PRO A 176
TYR A 379
VAL A 175
 None
 1.05A 3sufC-5w4bA:
undetectable		 3sufC-5w4bA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xxu RIBOSOMAL PROTEIN
ES25

(Toxoplasma
gondii) 		PF03297
(Ribosomal_S25) 		4 SER Z 127
ARG Z 130
PRO Z 115
TYR Z 153
 C  21531 ( 2.5A)
C  21531 ( 2.8A)
None
None
 1.37A 3sufC-5xxuZ:
undetectable		 3sufC-5xxuZ:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717

(Pseudoalteromonas
arctica) 		no annotation 4 SER A 219
PRO A 273
TYR A 188
VAL A 274
 None
 1.36A 3sufC-5yl7A:
undetectable		 3sufC-5yl7A:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b6l GLYCOSYL HYDROLASE
FAMILY 2, SUGAR
BINDING DOMAIN
PROTEIN

(Bacteroides
cellulosilyticus) 		no annotation 4 SER A 357
ARG A 355
TYR A 498
VAL A 376
 None
 1.28A 3sufC-6b6lA:
undetectable		 3sufC-6b6lA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f5d ATP SYNTHASE DELTA
SUBUNIT

(Trypanosoma
brucei) 		no annotation 4 SER H 106
ARG H  34
PRO H  49
VAL H  50
 None
 1.41A 3sufC-6f5dH:
undetectable		 3sufC-6f5dH:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE] 1
SUBUNIT C2

(Mus musculus) 		no annotation 4 ARG d  51
PRO d  52
TYR O 308
VAL d  53
 None
None
None
3PE  M 506 (-4.3A)
 1.33A 3sufC-6g2jd:
undetectable		 3sufC-6g2jd:
20.00