SIMILAR PATTERNS OF AMINO ACIDS FOR 3SUE_C_SUEC1201_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dus MJ0882

(Methanocaldococcus
jannaschii) 		PF05175
(MTS) 		4 TYR A  37
ILE A  46
LEU A  47
LYS A  45
 None
 1.13A 3sueC-1dusA:
undetectable		 3sueC-1dusA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gvz KALLIKREIN-1E2

(Equus caballus) 		PF00089
(Trypsin) 		4 TYR A 137
ILE A 120
LEU A  46
LYS A 119
 None
 1.20A 3sueC-1gvzA:
9.5		 3sueC-1gvzA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h2s SENSORY RHODOPSIN II

(Natronomonas
pharaonis) 		PF01036
(Bac_rhodopsin) 		4 TYR A 139
ILE A 156
LEU A 159
LYS A 157
 None
 1.27A 3sueC-1h2sA:
undetectable		 3sueC-1h2sA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h2s SENSORY RHODOPSIN II

(Natronomonas
pharaonis) 		PF01036
(Bac_rhodopsin) 		4 TYR A 140
ILE A 156
LEU A 159
LYS A 157
 None
 1.21A 3sueC-1h2sA:
undetectable		 3sueC-1h2sA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hxj BETA-GLUCOSIDASE

(Zea mays) 		PF00232
(Glyco_hydro_1) 		4 PHE A 332
TYR A 375
ILE A 336
LYS A 334
 None
 1.21A 3sueC-1hxjA:
undetectable		 3sueC-1hxjA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i5p PESTICIDIAL CRYSTAL
PROTEIN CRY2AA

(Bacillus
thuringiensis) 		PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N)
PF09131
(Endotoxin_mid) 		4 PHE A 494
TYR A 491
ILE A 258
LEU A  62
 None
 1.34A 3sueC-1i5pA:
0.0		 3sueC-1i5pA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ioo SF11-RNASE

(Nicotiana alata) 		PF00445
(Ribonuclease_T2) 		4 PHE A  29
TYR A 164
LEU A 111
LYS A 112
 None
None
None
NAG  A 197 (-2.9A)
 1.35A 3sueC-1iooA:
undetectable		 3sueC-1iooA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j3u ASPARTASE

(Bacillus sp.
YM55-1) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		4 PHE A 253
ILE A  46
LEU A  49
LYS A  47
 None
 1.32A 3sueC-1j3uA:
undetectable		 3sueC-1j3uA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jcm INDOLE-3-GLYCEROL-PH
OSPHATE SYNTHASE

(Escherichia
coli) 		PF00218
(IGPS) 		4 PHE P  99
TYR P 129
ILE P  51
LEU P  52
 None
 1.35A 3sueC-1jcmP:
undetectable		 3sueC-1jcmP:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ksh ARF-LIKE PROTEIN 2

(Mus musculus) 		PF00025
(Arf) 		4 PHE A  50
TYR A  76
ILE A  88
LEU A  19
 None
 1.27A 3sueC-1kshA:
undetectable		 3sueC-1kshA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lf9 GLUCOAMYLASE

(Thermoanaerobacterium
thermosaccharolyticum) 		PF00723
(Glyco_hydro_15)
PF09137
(Glucodextran_N) 		4 PHE A 139
TYR A 152
ILE A 124
LEU A 109
 None
 1.20A 3sueC-1lf9A:
0.0		 3sueC-1lf9A:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rlh CONSERVED
HYPOTHETICAL PROTEIN

(Thermoplasma
acidophilum) 		PF04008
(Adenosine_kin) 		4 PHE A  40
TYR A  13
ILE A  79
LEU A  78
 None
 1.36A 3sueC-1rlhA:
undetectable		 3sueC-1rlhA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xea OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY

(Vibrio cholerae) 		PF01408
(GFO_IDH_MocA) 		4 TYR A  56
ILE A  28
LEU A   3
LYS A   4
 None
 1.30A 3sueC-1xeaA:
undetectable		 3sueC-1xeaA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xkt FATTY ACID SYNTHASE

(Homo sapiens) 		PF00975
(Thioesterase) 		4 PHE A2418
TYR A2425
ILE A2405
LEU A2411
 None
 1.24A 3sueC-1xktA:
undetectable		 3sueC-1xktA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yj8 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE

(Plasmodium
falciparum) 		PF01210
(NAD_Gly3P_dh_N)
PF07479
(NAD_Gly3P_dh_C) 		4 PHE A 264
TYR A 330
ILE A 145
LYS A 152
 None
 1.18A 3sueC-1yj8A:
undetectable		 3sueC-1yj8A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z3z DIALKYLGLYCINE
DECARBOXYLASE

(Burkholderia
cepacia) 		PF00202
(Aminotran_3) 		4 PHE A 207
TYR A 150
ILE A 283
LEU A 268
 None
 1.22A 3sueC-1z3zA:
undetectable		 3sueC-1z3zA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d1f THREONINE SYNTHASE

(Mycobacterium
tuberculosis) 		PF00291
(PALP) 		4 PHE A  68
ILE A  42
LEU A  57
LYS A  58
 PLP  A 500 (-4.7A)
None
None
None
 1.23A 3sueC-2d1fA:
undetectable		 3sueC-2d1fA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gre DEBLOCKING
AMINOPEPTIDASE

(Bacillus cereus) 		PF05343
(Peptidase_M42) 		4 TYR A 103
ILE A  12
LEU A  15
LYS A  13
 None
 1.21A 3sueC-2greA:
1.9		 3sueC-2greA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j1n OUTER MEMBRANE
PROTEIN C

(Escherichia
coli) 		PF00267
(Porin_1) 		4 TYR A  94
ILE A 193
LEU A 225
LYS A 226
 None
 1.36A 3sueC-2j1nA:
undetectable		 3sueC-2j1nA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jgz G2/MITOTIC-SPECIFIC
CYCLIN-B1

(Homo sapiens) 		PF00134
(Cyclin_N)
PF02984
(Cyclin_C) 		4 TYR B 371
ILE B 355
LEU B 356
LYS B 354
 None
 1.33A 3sueC-2jgzB:
undetectable		 3sueC-2jgzB:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l6x GREEN-LIGHT
ABSORBING
PROTEORHODOPSIN

(uncultured
marine gamma
proteobacterium
EBAC31A08) 		PF01036
(Bac_rhodopsin) 		4 TYR A 204
ILE A 232
LEU A 233
LYS A 231
 None
None
None
RET  A 301 (-1.3A)
 1.11A 3sueC-2l6xA:
undetectable		 3sueC-2l6xA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o1o PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE

(Cryptosporidium
parvum) 		PF00348
(polyprenyl_synt) 		4 TYR A 217
ILE A 143
LEU A 146
LYS A 147
 None
 1.05A 3sueC-2o1oA:
undetectable		 3sueC-2o1oA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o3a UPF0106 PROTEIN
AF_0751

(Archaeoglobus
fulgidus) 		PF01994
(Trm56) 		4 TYR A  82
ILE A  93
LEU A  90
LYS A  89
 None
 1.24A 3sueC-2o3aA:
undetectable		 3sueC-2o3aA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o3e NEUROLYSIN

(Rattus
norvegicus) 		PF01432
(Peptidase_M3) 		4 PHE A 327
ILE A 314
LEU A 317
LYS A 318
 None
 0.86A 3sueC-2o3eA:
undetectable		 3sueC-2o3eA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p4o HYPOTHETICAL PROTEIN

(Nostoc
punctiforme) 		no annotation 4 PHE A 176
TYR A 225
ILE A 206
LEU A 191
 None
 1.34A 3sueC-2p4oA:
undetectable		 3sueC-2p4oA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pxs GFP-LIKE FLUORESCENT
CHROMOPROTEIN FP506

(Zoanthus sp.) 		PF01353
(GFP) 		4 PHE A 181
ILE A 160
LEU A 161
LYS A 162
 None
 1.15A 3sueC-2pxsA:
undetectable		 3sueC-2pxsA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wqp POLYSIALIC ACID
CAPSULE BIOSYNTHESIS
PROTEIN SIAC

(Neisseria
meningitidis) 		PF03102
(NeuB)
PF08666
(SAF) 		4 PHE A 237
TYR A  45
ILE A 232
LEU A 233
 None
 1.21A 3sueC-2wqpA:
undetectable		 3sueC-2wqpA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y4t DNAJ HOMOLOG
SUBFAMILY C MEMBER 3

(Homo sapiens) 		PF00226
(DnaJ)
PF09976
(TPR_21)
PF13181
(TPR_8) 		4 TYR A 262
ILE A 208
LEU A 211
LYS A 212
 None
 1.02A 3sueC-2y4tA:
undetectable		 3sueC-2y4tA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zsj THREONINE SYNTHASE

(Aquifex
aeolicus) 		PF00291
(PALP) 		4 PHE A  62
ILE A  34
LEU A  51
LYS A  52
 PLP  A1101 (-4.5A)
None
None
None
 1.15A 3sueC-2zsjA:
undetectable		 3sueC-2zsjA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b4r PUTATIVE ZINC
METALLOPROTEASE
MJ0392

(Methanocaldococcus
jannaschii) 		PF02163
(Peptidase_M50) 		4 PHE A 202
ILE A 173
LEU A 177
LYS A 175
 None
 1.24A 3sueC-3b4rA:
undetectable		 3sueC-3b4rA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bjq PHAGE-RELATED
PROTEIN

(Bordetella
bronchiseptica) 		PF03864
(Phage_cap_E) 		4 TYR A 248
ILE A 209
LEU A 212
LYS A 213
 None
 0.90A 3sueC-3bjqA:
undetectable		 3sueC-3bjqA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dqz ALPHA-HYDROXYNITRILE
LYASE-LIKE PROTEIN

(Arabidopsis
thaliana) 		PF12697
(Abhydrolase_6) 		4 TYR A 167
ILE A 231
LEU A 246
LYS A 242
 None
 1.30A 3sueC-3dqzA:
undetectable		 3sueC-3dqzA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eei 5-METHYLTHIOADENOSIN
E
NUCLEOSIDASE/S-ADENO
SYLHOMOCYSTEINE
NUCLEOSIDASE

(Neisseria
meningitidis) 		PF01048
(PNP_UDP_1) 		4 TYR A  37
ILE A 229
LEU A 233
LYS A 231
 None
 1.30A 3sueC-3eeiA:
undetectable		 3sueC-3eeiA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ep7 S-ADENOSYLMETHIONINE
DECARBOXYLASE ALPHA
CHAIN

(Homo sapiens) 		PF01536
(SAM_decarbox) 		4 TYR A 158
ILE A  78
LEU A  79
LYS A  80
 None
 1.29A 3sueC-3ep7A:
undetectable		 3sueC-3ep7A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3epr HYDROLASE, HALOACID
DEHALOGENASE-LIKE
FAMILY

(Streptococcus
agalactiae) 		PF13242
(Hydrolase_like)
PF13344
(Hydrolase_6) 		4 PHE A 230
TYR A 209
ILE A  16
LEU A  12
 GOL  A 265 (-3.7A)
None
None
None
 1.35A 3sueC-3eprA:
undetectable		 3sueC-3eprA:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eu8 PUTATIVE
GLUCOAMYLASE

(Bacteroides
fragilis) 		PF10091
(Glycoamylase)
PF11329
(DUF3131) 		4 PHE A 280
TYR A 271
ILE A 366
LEU A 363
 None
 1.31A 3sueC-3eu8A:
undetectable		 3sueC-3eu8A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g0t PUTATIVE
AMINOTRANSFERASE

(Porphyromonas
gingivalis) 		PF00155
(Aminotran_1_2) 		4 PHE A  93
TYR A 240
ILE A 273
LEU A 271
 None
NA  A 437 ( 4.6A)
None
None
 1.33A 3sueC-3g0tA:
undetectable		 3sueC-3g0tA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gve YFKN PROTEIN

(Bacillus
subtilis) 		PF00149
(Metallophos) 		4 PHE A  35
TYR A  24
ILE A  44
LEU A  43
 None
 1.27A 3sueC-3gveA:
undetectable		 3sueC-3gveA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hn2 2-DEHYDROPANTOATE
2-REDUCTASE

(Geobacter
metallireducens) 		PF02558
(ApbA)
PF08546
(ApbA_C) 		4 PHE A  28
TYR A  14
ILE A  87
LEU A  86
 None
 1.11A 3sueC-3hn2A:
undetectable		 3sueC-3hn2A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hum PENICILLIN-BINDING
PROTEIN 4

(Staphylococcus
aureus) 		PF00768
(Peptidase_S11)
PF09211
(DUF1958) 		4 PHE A 243
TYR A 239
LEU A 258
LYS A 259
 CEW  A 501 (-4.6A)
None
None
CEW  A 501 ( 4.4A)
 1.30A 3sueC-3humA:
undetectable		 3sueC-3humA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ig3 PLXNA3 PROTEIN

(Mus musculus) 		PF08337
(Plexin_cytopl) 		4 TYR A1441
ILE A1470
LEU A1469
LYS A1468
 None
 1.07A 3sueC-3ig3A:
undetectable		 3sueC-3ig3A:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l4n MONOTHIOL
GLUTAREDOXIN-6

(Saccharomyces
cerevisiae) 		PF00462
(Glutaredoxin) 		4 PHE A 220
TYR A 150
ILE A 122
LEU A 125
 None
 1.18A 3sueC-3l4nA:
undetectable		 3sueC-3l4nA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ozy PUTATIVE MANDELATE
RACEMASE

(Bordetella
bronchiseptica) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 PHE A  89
TYR A 257
ILE A  81
LEU A  84
 None
 1.28A 3sueC-3ozyA:
undetectable		 3sueC-3ozyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r2h BACTERIOFERRITIN

(Pseudomonas
aeruginosa) 		PF00210
(Ferritin) 		4 TYR A 132
ILE A 104
LEU A 119
LYS A 120
 None
 1.19A 3sueC-3r2hA:
undetectable		 3sueC-3r2hA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rl3 METALLOPHOSPHOESTERA
SE MPPED2

(Rattus
norvegicus) 		PF00149
(Metallophos) 		4 PHE A 286
TYR A 267
ILE A 112
LEU A  81
 None
 1.12A 3sueC-3rl3A:
undetectable		 3sueC-3rl3A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ryt PLEXIN-A1

(Mus musculus) 		PF08337
(Plexin_cytopl) 		4 TYR A1463
ILE A1492
LEU A1491
LYS A1490
 None
 0.93A 3sueC-3rytA:
undetectable		 3sueC-3rytA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tij NUPC FAMILY PROTEIN

(Vibrio cholerae) 		PF01773
(Nucleos_tra2_N)
PF07662
(Nucleos_tra2_C)
PF07670
(Gate) 		4 TYR A  48
ILE A 199
LEU A 202
LYS A 198
 None
 1.27A 3sueC-3tijA:
undetectable		 3sueC-3tijA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE

(Pachysandra
terminalis) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 PHE A 478
TYR A 435
ILE A 378
LEU A 531
 None
 1.36A 3sueC-3uggA:
0.8		 3sueC-3uggA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3va7 KLLA0E08119P

(Kluyveromyces
lactis) 		PF00289
(Biotin_carb_N)
PF00364
(Biotin_lipoyl)
PF02626
(CT_A_B)
PF02682
(CT_C_D)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		4 PHE A1349
TYR A1606
ILE A1298
LEU A1297
 BTI  A1901 (-4.6A)
None
None
None
 1.36A 3sueC-3va7A:
undetectable		 3sueC-3va7A:
11.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vpq GLUTATHIONE
S-TRANSFERASE SIGMA

(Bombyx mori) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 PHE A 128
ILE A 136
LEU A 133
LYS A 132
 None
PGO  A 303 ( 4.3A)
None
PGO  A 309 (-2.7A)
 1.26A 3sueC-3vpqA:
undetectable		 3sueC-3vpqA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c00 TRANSLOCATION AND
ASSEMBLY MODULE TAMA

(Escherichia
coli) 		PF01103
(Bac_surface_Ag)
PF07244
(POTRA)
PF17243
(POTRA_TamA_1) 		4 PHE A 429
TYR A 415
LEU A 499
LYS A 498
 None
 1.20A 3sueC-4c00A:
undetectable		 3sueC-4c00A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fuv PORIN PROTEIN
ASSOCIATED WITH
IMIPENEM RESISTANCE

(Acinetobacter
baumannii) 		no annotation 4 TYR A  41
ILE A  17
LEU A  16
LYS A  13
 None
C8E  A 308 ( 4.9A)
C8E  A 308 (-4.8A)
None
 1.16A 3sueC-4fuvA:
undetectable		 3sueC-4fuvA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gpg PROTEASE 1

(Achromobacter
lyticus) 		PF00089
(Trypsin) 		4 PHE A 114
TYR A  51
ILE A 198
LEU A 209
 None
 1.18A 3sueC-4gpgA:
10.9		 3sueC-4gpgA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i1a RESPONSE REGULATOR
ASPARTATE
PHOSPHATASE I

(Bacillus
subtilis) 		PF13424
(TPR_12) 		4 PHE A 207
TYR A 200
ILE A 248
LEU A 249
 None
 1.17A 3sueC-4i1aA:
undetectable		 3sueC-4i1aA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i9c RESPONSE REGULATOR
ASPARTATE
PHOSPHATASE F

(Bacillus
subtilis) 		PF12895
(ANAPC3)
PF13424
(TPR_12) 		4 PHE A 103
ILE A 132
LEU A 131
LYS A 130
 None
 1.25A 3sueC-4i9cA:
undetectable		 3sueC-4i9cA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4it1 PUTATIVE GLUCARATE
DEHYDRATASE

(Pseudomonas
fluorescens) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 PHE A 187
TYR A 350
LEU A 192
LYS A 191
 None
 1.15A 3sueC-4it1A:
undetectable		 3sueC-4it1A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j05 PHOSPHATE
TRANSPORTER

(Serendipita
indica) 		PF00083
(Sugar_tr) 		4 PHE A 485
TYR A 328
ILE A 394
LEU A 398
 None
PO4  A 600 (-4.5A)
None
None
 1.24A 3sueC-4j05A:
undetectable		 3sueC-4j05A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j3b M1 FAMILY
AMINOPEPTIDASE

(Plasmodium
falciparum) 		PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C) 		4 TYR A1018
ILE A 978
LEU A 982
LYS A 980
 None
 1.28A 3sueC-4j3bA:
undetectable		 3sueC-4j3bA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jza UNCHARACTERIZED
PROTEIN

(Legionella
longbeachae) 		no annotation 4 PHE A 580
TYR A 476
ILE A 538
LEU A 537
 None
 1.04A 3sueC-4jzaA:
undetectable		 3sueC-4jzaA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lzk PIXA INCLUSION BODY
PROTEIN

(Burkholderia
cenocepacia) 		PF12306
(PixA) 		4 PHE A 172
TYR A  27
ILE A  96
LEU A  95
 None
 1.31A 3sueC-4lzkA:
undetectable		 3sueC-4lzkA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mb5 CHITINASE 60

(Moritella
marina) 		PF00704
(Glyco_hydro_18)
PF16403
(DUF5011) 		4 TYR A 211
ILE A 255
LEU A 254
LYS A 263
 None
 1.18A 3sueC-4mb5A:
undetectable		 3sueC-4mb5A:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mea PREDICTED PROTEIN

(Acinetobacter
nosocomialis) 		PF00561
(Abhydrolase_1) 		4 PHE A  87
TYR A 153
ILE A  66
LEU A  73
 None
 0.86A 3sueC-4meaA:
undetectable		 3sueC-4meaA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n42 XYLANASE AND
ALPHA-AMYLASE
INHIBITOR PROTEIN
ISOFORM III

(Scadoxus
multiflorus) 		PF00704
(Glyco_hydro_18) 		4 TYR A 256
ILE A 267
LEU A 268
LYS A 266
 None
 1.30A 3sueC-4n42A:
undetectable		 3sueC-4n42A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n74 PREDICTED OUTER
MEMBRANE PROTEIN AND
SURFACE ANTIGEN

(Escherichia
coli) 		PF01103
(Bac_surface_Ag) 		4 PHE A 429
TYR A 415
LEU A 499
LYS A 498
 None
 1.23A 3sueC-4n74A:
undetectable		 3sueC-4n74A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nsy LYSYL ENDOPEPTIDASE

(Lysobacter
enzymogenes) 		PF13365
(Trypsin_2) 		4 PHE A 114
TYR A  51
ILE A 198
LEU A 209
 None
None
None
2OY  A 301 ( 4.2A)
 1.20A 3sueC-4nsyA:
11.1		 3sueC-4nsyA:
23.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4nwk HCV NS3 1A PROTEASE

(Hepacivirus C) 		PF02907
(Peptidase_S29) 		4 PHE A  43
TYR A  56
ILE A 132
LEU A 135
 2R8  A 301 (-4.6A)
None
2R8  A 301 (-4.3A)
2R8  A 301 (-4.4A)
 0.54A 3sueC-4nwkA:
35.1		 3sueC-4nwkA:
98.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qt9 PUTATIVE
GLUCOAMYLASE

(Bacteroides
caccae) 		PF10091
(Glycoamylase) 		4 PHE A 290
TYR A 281
ILE A 376
LEU A 373
 ACT  A 501 ( 4.9A)
None
None
None
 1.28A 3sueC-4qt9A:
undetectable		 3sueC-4qt9A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qts CRISPR TYPE
III-ASSOCIATED RAMP
PROTEIN CSM4

(Methanocaldococcus
jannaschii) 		PF03787
(RAMPs) 		4 PHE A 206
ILE A  69
LEU A  74
LYS A  68
 None
 1.25A 3sueC-4qtsA:
undetectable		 3sueC-4qtsA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ras OXIDOREDUCTASE,
NAD-BINDING/IRON-SUL
FUR CLUSTER-BINDING
PROTEIN

(Nitratireductor
pacificus) 		PF12838
(Fer4_7)
PF13486
(Dehalogenase) 		4 PHE A 367
ILE A 356
LEU A 359
LYS A 357
 None
 1.34A 3sueC-4rasA:
undetectable		 3sueC-4rasA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4reg UNCHARACTERIZED
PROTEIN

(Pyrococcus
furiosus) 		PF01905
(DevR) 		4 PHE A  67
ILE A 243
LEU A 242
LYS A 240
 None
 1.37A 3sueC-4regA:
undetectable		 3sueC-4regA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w5z CHITINASE 60

(Moritella
marina) 		PF00704
(Glyco_hydro_18) 		4 TYR A 211
ILE A 255
LEU A 254
LYS A 263
 None
 1.21A 3sueC-4w5zA:
undetectable		 3sueC-4w5zA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w82 FATTY ACID SYNTHASE

(Homo sapiens) 		PF00107
(ADH_zinc_N) 		4 PHE A1603
TYR A1567
LEU A1599
LYS A1620
 None
 1.18A 3sueC-4w82A:
undetectable		 3sueC-4w82A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wph UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7

(Homo sapiens) 		PF12436
(USP7_ICP0_bdg) 		4 PHE A 726
TYR A 692
ILE A 713
LEU A 716
 None
 1.28A 3sueC-4wphA:
undetectable		 3sueC-4wphA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a55 ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE

(Streptococcus
pneumoniae) 		PF12905
(Glyco_hydro_101)
PF17451
(Glyco_hyd_101C) 		4 PHE A 618
ILE A 693
LEU A 649
LYS A 650
 None
 1.30A 3sueC-5a55A:
undetectable		 3sueC-5a55A:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dcz TANKYRASE-2

(Homo sapiens) 		PF00644
(PARP) 		4 PHE A1098
ILE A 956
LEU A 955
LYS A 999
 None
 1.17A 3sueC-5dczA:
undetectable		 3sueC-5dczA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e4r KETOL-ACID
REDUCTOISOMERASE

(Ignisphaera
aggregans) 		PF01450
(IlvC)
PF07991
(IlvN) 		4 PHE A 110
TYR A 404
LEU A  89
LYS A  87
 None
None
EDO  A 505 (-4.4A)
None
 1.02A 3sueC-5e4rA:
undetectable		 3sueC-5e4rA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ei3 EUKARYOTIC
TRANSLATION
INITIATION FACTOR 4E

(Homo sapiens) 		PF01652
(IF4E) 		4 PHE A 215
TYR A 145
ILE A 115
LEU A 114
 None
 1.24A 3sueC-5ei3A:
0.6		 3sueC-5ei3A:
17.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5eqq NS3 PROTEASE

(Hepacivirus C) 		PF02907
(Peptidase_S29) 		5 PHE A1043
TYR A1056
ILE A1132
LEU A1135
LYS A1136
 5RS  A1203 (-4.3A)
SO4  A1201 ( 4.5A)
5RS  A1203 ( 4.1A)
5RS  A1203 (-4.2A)
5RS  A1203 (-4.8A)
 0.63A 3sueC-5eqqA:
34.3		 3sueC-5eqqA:
93.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE

(Campylobacter
jejuni) 		PF00701
(DHDPS) 		4 TYR A 196
ILE A 246
LEU A 247
LYS A 245
 None
 1.30A 3sueC-5f1uA:
undetectable		 3sueC-5f1uA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gl7 METHIONINE--TRNA
LIGASE, CYTOPLASMIC

(Homo sapiens) 		PF09334
(tRNA-synt_1g) 		4 PHE A 551
TYR A 297
ILE A 624
LEU A 621
 None
 1.28A 3sueC-5gl7A:
undetectable		 3sueC-5gl7A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h5b THYMIDYLATE KINASE

(Aquifex
aeolicus) 		no annotation 4 PHE B  91
TYR B  34
ILE B 172
LEU B 128
 None
 1.14A 3sueC-5h5bB:
undetectable		 3sueC-5h5bB:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i8i UREA AMIDOLYASE

(Kluyveromyces
lactis) 		PF00289
(Biotin_carb_N)
PF01425
(Amidase)
PF02626
(CT_A_B)
PF02682
(CT_C_D)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		4 PHE A1349
TYR A1606
ILE A1298
LEU A1297
 None
 1.34A 3sueC-5i8iA:
undetectable		 3sueC-5i8iA:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j3r MONOTHIOL
GLUTAREDOXIN-6

(Saccharomyces
cerevisiae) 		PF00462
(Glutaredoxin) 		4 PHE A 220
TYR A 150
ILE A 122
LEU A 125
 None
 1.23A 3sueC-5j3rA:
undetectable		 3sueC-5j3rA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j7t UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7

(Homo sapiens) 		PF00443
(UCH)
PF12436
(USP7_ICP0_bdg) 		4 PHE A 726
TYR A 692
ILE A 713
LEU A 716
 None
 1.31A 3sueC-5j7tA:
0.8		 3sueC-5j7tA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ool 39S RIBOSOMAL
PROTEIN L45,
MITOCHONDRIAL

(Homo sapiens) 		PF00181
(Ribosomal_L2)
PF03947
(Ribosomal_L2_C) 		4 PHE d 228
TYR d 178
ILE d 276
LEU d 277
 None
 1.00A 3sueC-5oold:
undetectable		 3sueC-5oold:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tqw INHIBITOR OF NUCLEAR
FACTOR KAPPA-B
KINASE SUBUNIT ALPHA

(Homo sapiens) 		PF00069
(Pkinase) 		4 TYR A 441
ILE A 315
LEU A 386
LYS A 383
 None
 1.32A 3sueC-5tqwA:
undetectable		 3sueC-5tqwA:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tum TETRACYCLINE
DESTRUCTASE TET(56)

(Legionella
longbeachae) 		PF01494
(FAD_binding_3) 		4 PHE A  28
TYR A 323
ILE A  33
LEU A  32
 None
 1.12A 3sueC-5tumA:
undetectable		 3sueC-5tumA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ty7 PENICILLIN-BINDING
PROTEIN 4

(Staphylococcus
aureus) 		no annotation 4 PHE A 243
TYR A 239
LEU A 258
LYS A 259
 None
None
None
NFF  A 401 ( 4.8A)
 1.23A 3sueC-5ty7A:
undetectable		 3sueC-5ty7A:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u09 CANNABINOID RECEPTOR
1,GLGA GLYCOGEN
SYNTHASE

(Homo sapiens;
Pyrococcus
abyssi) 		PF00001
(7tm_1)
PF00534
(Glycos_transf_1) 		4 PHE A 208
TYR A 215
ILE A 353
LEU A 352
 None
 1.19A 3sueC-5u09A:
undetectable		 3sueC-5u09A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v8d BACILLUS CEREUS
PATB1

(Bacillus cereus) 		no annotation 4 TYR C 165
ILE C 177
LEU C 179
LYS C 178
 None
 1.11A 3sueC-5v8dC:
undetectable		 3sueC-5v8dC:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v8e BACILLUS CEREUS
PATB1

(Bacillus cereus) 		no annotation 4 TYR A 165
ILE A 177
LEU A 179
LYS A 178
 None
 1.14A 3sueC-5v8eA:
undetectable		 3sueC-5v8eA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wdx JFH-1 NS3

(Hepacivirus C) 		no annotation 4 PHE A  43
TYR A  56
ILE A 132
LEU A 135
 None
 0.64A 3sueC-5wdxA:
27.0		 3sueC-5wdxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xhq APOLIPOPROTEIN
N-ACYLTRANSFERASE

(Escherichia
coli) 		PF00795
(CN_hydrolase) 		4 PHE A 400
TYR A 406
ILE A 391
LEU A 392
 None
 0.94A 3sueC-5xhqA:
undetectable		 3sueC-5xhqA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xmd EPOXIDE HYDROLASE A

(Vigna radiata) 		no annotation 4 PHE A 319
TYR A 286
ILE A  87
LEU A  28
 None
 1.19A 3sueC-5xmdA:
undetectable		 3sueC-5xmdA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xqh PROTEIN ROGDI
HOMOLOG

(Homo sapiens) 		PF10259
(Rogdi_lz) 		4 PHE A 100
ILE A  62
LEU A  63
LYS A  72
 None
 1.19A 3sueC-5xqhA:
undetectable		 3sueC-5xqhA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yt0 PROBABLE TRANSLATION
INITIATION FACTOR
IF-2

(Aeropyrum
pernix) 		no annotation 4 PHE A 107
TYR A 230
ILE A  57
LEU A  84
 None
 1.25A 3sueC-5yt0A:
1.8		 3sueC-5yt0A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6azh TETR FAMILY
TRANSCRIPTIONAL
REGULATOR

(Clostridium
perfringens) 		no annotation 4 TYR A  92
ILE A  69
LEU A  66
LYS A  65
 None
 1.01A 3sueC-6azhA:
undetectable		 3sueC-6azhA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b3r PIEZO-TYPE
MECHANOSENSITIVE ION
CHANNEL COMPONENT 1

(Mus musculus) 		no annotation 4 TYR A1048
ILE A1077
LEU A1080
LYS A1078
 None
 1.10A 3sueC-6b3rA:
undetectable		 3sueC-6b3rA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ei3 PROTON-DEPENDENT
OLIGOPEPTIDE
TRANSPORTER FAMILY
PROTEIN

(Xanthomonas
campestris) 		no annotation 4 TYR A 160
ILE A 132
LEU A 135
LYS A 133
 None
 1.16A 3sueC-6ei3A:
undetectable		 3sueC-6ei3A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fj4 ENDO-1,4-BETA-XYLANA
SE Y

(Ruminiclostridium
thermocellum) 		no annotation 4 TYR A1049
ILE A 998
LEU A1003
LYS A1005
 None
 1.30A 3sueC-6fj4A:
undetectable		 3sueC-6fj4A:
16.24