SIMILAR PATTERNS OF AMINO ACIDS FOR 3SUD_D_SUED1201

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1apy ASPARTYLGLUCOSAMINID
ASE

(Homo sapiens) 		PF01112
(Asparaginase_2) 		5 GLY B 213
VAL A  79
ALA B 220
ALA B 222
ALA B 231
 None
 0.91A 3sudD-1apyB:
undetectable		 3sudD-1apyB:
22.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1cu1 PROTEIN
(PROTEASE/HELICASE
NS3)

(Hepacivirus C) 		PF02907
(Peptidase_S29)
PF07652
(Flavi_DEAD) 		10 GLN A  41
HIS A  57
GLY A  58
VAL A  78
ASP A  81
GLY A 137
PHE A 154
ALA A 156
ALA A 157
ASP A 168
 None
 0.62A 3sudD-1cu1A:
34.6		 3sudD-1cu1A:
80.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dab P.69 PERTACTIN

(Bordetella
pertussis) 		PF03212
(Pertactin) 		5 GLY A 260
GLY A 263
ALA A 207
ALA A 211
SER A 269
 None
 1.04A 3sudD-1dabA:
undetectable		 3sudD-1dabA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eye DIHYDROPTEROATE
SYNTHASE I

(Mycobacterium
tuberculosis) 		PF00809
(Pterin_bind) 		5 GLY A 232
ALA A 259
ALA A 238
SER A 241
ASP A 262
 None
 1.02A 3sudD-1eyeA:
undetectable		 3sudD-1eyeA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f56 PLANTACYANIN

(Spinacia
oleracea) 		PF02298
(Cu_bind_like) 		5 GLY A  22
VAL A   2
GLY A  68
ALA A  90
ALA A  87
 None
 1.03A 3sudD-1f56A:
undetectable		 3sudD-1f56A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gq2 MALIC ENZYME

(Columba livia) 		PF00390
(malic)
PF03949
(Malic_M) 		5 GLY A 192
GLY A 477
ALA A 475
SER A 285
ASP A 278
 None
None
None
None
OXL  A1583 ( 4.6A)
 0.93A 3sudD-1gq2A:
undetectable		 3sudD-1gq2A:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hpg GLUTAMIC ACID
SPECIFIC PROTEASE

(Streptomyces
griseus) 		no annotation 5 HIS A  57
ASP A 102
GLY A 193
ALA A 226
SER A 225
 None
 1.00A 3sudD-1hpgA:
11.1		 3sudD-1hpgA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1htr GASTRICSIN
PROGASTRICSIN (PRO
SEGMENT)

(Homo sapiens) 		PF00026
(Asp)
PF07966
(A1_Propeptide) 		5 GLY B 305
VAL B 288
GLY B  34
ALA P  35
ASP P  33
 None
 0.94A 3sudD-1htrB:
undetectable		 3sudD-1htrB:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i9a ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE

(Escherichia
coli) 		PF00293
(NUDIX) 		5 HIS A  69
GLY A  68
VAL A 117
ALA A  24
ALA A  23
 MN  A1001 (-3.1A)
None
None
None
None
 0.80A 3sudD-1i9aA:
undetectable		 3sudD-1i9aA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jal YCHF PROTEIN

(Haemophilus
influenzae) 		PF01926
(MMR_HSR1)
PF06071
(YchF-GTPase_C) 		5 GLY A  75
GLY A  83
ALA A  80
ALA A 135
SER A 139
 None
 0.96A 3sudD-1jalA:
undetectable		 3sudD-1jalA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m22 PEPTIDE AMIDASE

(Stenotrophomonas
maltophilia) 		PF01425
(Amidase) 		6 GLY A 205
GLY A 220
ALA A 218
ALA A 265
ALA A 271
ASP A 270
 None
 1.22A 3sudD-1m22A:
undetectable		 3sudD-1m22A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m7j D-AMINOACYLASE

(Alcaligenes
faecalis) 		PF07969
(Amidohydro_3) 		5 GLY A  56
VAL A  59
ALA A 435
ALA A 438
SER A 440
 None
 1.03A 3sudD-1m7jA:
undetectable		 3sudD-1m7jA:
19.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ns3 NS3 PROTEASE

(Hepacivirus C) 		PF02907
(Peptidase_S29) 		9 GLN A  41
HIS A  57
GLY A  58
ASP A  81
GLY A 137
PHE A 154
ALA A 156
ALA A 157
ASP A 168
 None
 0.82A 3sudD-1ns3A:
30.6		 3sudD-1ns3A:
77.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ns3 NS3 PROTEASE

(Hepacivirus C) 		PF02907
(Peptidase_S29) 		9 GLN A  41
HIS A  57
GLY A  58
VAL A  78
ASP A  81
GLY A 137
PHE A 154
ALA A 156
ALA A 157
 None
 0.79A 3sudD-1ns3A:
30.6		 3sudD-1ns3A:
77.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pn3 GLYCOSYLTRANSFERASE
GTFA

(Amycolatopsis
orientalis) 		PF03033
(Glyco_transf_28) 		5 GLY A 259
ALA A 261
ALA A 237
ALA A 240
ASP A 238
 None
 0.98A 3sudD-1pn3A:
undetectable		 3sudD-1pn3A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1szn ALPHA-GALACTOSIDASE

(Trichoderma
reesei) 		PF16499
(Melibiase_2) 		5 GLY A  66
ASP A 117
GLY A  62
ALA A 109
ALA A 102
 None
 1.00A 3sudD-1sznA:
undetectable		 3sudD-1sznA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wle SERYL-TRNA
SYNTHETASE

(Bos taurus) 		PF00587
(tRNA-synt_2b) 		5 GLY A 254
GLY A 289
ALA A 288
ALA A 283
SER A 309
 None
 1.00A 3sudD-1wleA:
undetectable		 3sudD-1wleA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aw5 NADP-DEPENDENT MALIC
ENZYME

(Homo sapiens) 		PF00390
(malic)
PF03949
(Malic_M) 		5 GLY A 182
GLY A 464
ALA A 462
SER A 275
ASP A 268
 None
 0.98A 3sudD-2aw5A:
undetectable		 3sudD-2aw5A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bht CYSTEINE SYNTHASE B

(Escherichia
coli) 		PF00291
(PALP) 		5 GLY A  73
VAL A  40
ALA A 102
SER A 288
ASP A 284
 None
 1.01A 3sudD-2bhtA:
undetectable		 3sudD-2bhtA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c11 MEMBRANE COPPER
AMINE OXIDASE

(Homo sapiens) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3) 		5 VAL A 352
ASP A 351
GLY A 116
ALA A 109
ALA A 108
 None
 1.03A 3sudD-2c11A:
undetectable		 3sudD-2c11A:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gah HETEROTETRAMERIC
SARCOSINE OXIDASE
ALPHA-SUBUNIT

(Stenotrophomonas
maltophilia) 		PF01571
(GCV_T)
PF07992
(Pyr_redox_2)
PF08669
(GCV_T_C)
PF13510
(Fer2_4) 		5 VAL A 410
GLY A 444
ALA A 442
ALA A 438
ALA A 437
 None
 1.04A 3sudD-2gahA:
2.1		 3sudD-2gahA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i3a N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE

(Mycobacterium
tuberculosis) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		5 GLY A  79
GLY A  43
ALA A  13
ALA A  17
SER A  18
 None
 1.02A 3sudD-2i3aA:
undetectable		 3sudD-2i3aA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iou PERTACTIN
EXTRACELLULAR DOMAIN

(Bordetella
bronchiseptica) 		PF03212
(Pertactin) 		6 GLY G 164
VAL G 214
ASP G 183
GLY G 114
ALA G 143
ALA G 131
 None
 1.38A 3sudD-2iouG:
undetectable		 3sudD-2iouG:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2isq CYSTEINE SYNTHASE

(Arabidopsis
thaliana) 		PF00291
(PALP) 		5 GLY A 225
GLY A 267
PHE A 295
ALA A 273
ALA A 274
 PLP  A 400 (-3.5A)
None
None
None
None
 0.99A 3sudD-2isqA:
undetectable		 3sudD-2isqA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j0w LYSINE-SENSITIVE
ASPARTOKINASE 3

(Escherichia
coli) 		PF00696
(AA_kinase)
PF01842
(ACT) 		5 HIS A 260
GLY A 200
VAL A 258
SER A 338
ASP A 354
 None
ASP  A 502 (-4.2A)
ADP  A 820 (-3.7A)
None
None
 0.97A 3sudD-2j0wA:
undetectable		 3sudD-2j0wA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j92 PICORNAIN 3C

(Foot-and-mouth
disease virus) 		PF00548
(Peptidase_C3) 		5 HIS A  46
ASP A  84
GLY A 161
ALA A 163
ALA A 183
 None
 0.66A 3sudD-2j92A:
10.6		 3sudD-2j92A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kbe ATP-DEPENDENT RNA
HELICASE DBP5

(Saccharomyces
cerevisiae) 		PF00270
(DEAD) 		5 GLY A 249
GLY A 217
ALA A 169
ALA A 175
ASP A 239
 None
 0.98A 3sudD-2kbeA:
undetectable		 3sudD-2kbeA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME

(Bos taurus) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3) 		5 VAL A 351
ASP A 350
GLY A 115
ALA A 108
ALA A 107
 None
 0.97A 3sudD-2pncA:
undetectable		 3sudD-2pncA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q2e TYPE 2 DNA
TOPOISOMERASE 6
SUBUNIT B

(Methanosarcina
mazei) 		PF02518
(HATPase_c)
PF09239
(Topo-VIb_trans) 		5 GLY B 404
VAL B 414
PHE B 337
ALA B 339
SER B 341
 None
 1.01A 3sudD-2q2eB:
undetectable		 3sudD-2q2eB:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rhp THROMBOSPONDIN-2

(Homo sapiens) 		PF02412
(TSP_3)
PF05735
(TSP_C)
PF07645
(EGF_CA)
PF12947
(EGF_3) 		5 GLN A 728
GLY A 727
VAL A 980
GLY A 699
ALA A1109
 None
 1.03A 3sudD-2rhpA:
undetectable		 3sudD-2rhpA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xmo LMO2642 PROTEIN

(Listeria
monocytogenes) 		PF00149
(Metallophos) 		5 HIS A 243
GLY A 133
VAL A  48
ASP A  47
GLY A 214
 FE  A 556 (-3.4A)
None
None
MN  A 555 (-3.2A)
None
 1.01A 3sudD-2xmoA:
undetectable		 3sudD-2xmoA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xqh IMMUNOGLOBULIN-BINDI
NG PROTEIN EIBD

(Escherichia
coli) 		PF05658
(YadA_head) 		7 GLY A 173
GLY A 201
ALA A 190
ALA A 192
ALA A 206
SER A 211
ASP A 193
 None
 1.44A 3sudD-2xqhA:
undetectable		 3sudD-2xqhA:
25.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bdz P450CIN

(Citrobacter
braakii) 		PF00067
(p450) 		5 HIS A  52
VAL A 287
ALA A  48
ALA A  14
SER A   9
 None
HEM  A 450 (-4.8A)
None
None
None
 0.97A 3sudD-3bdzA:
undetectable		 3sudD-3bdzA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c24 PUTATIVE
OXIDOREDUCTASE

(Jannaschia sp.
CCS1) 		PF03807
(F420_oxidored)
PF16896
(PGDH_C) 		5 VAL A  71
GLY A 107
ALA A 103
ALA A 101
ALA A 187
 None
 1.04A 3sudD-3c24A:
undetectable		 3sudD-3c24A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dzb PREPHENATE
DEHYDROGENASE

(Streptococcus
thermophilus) 		PF02153
(PDH) 		5 GLY A  16
VAL A  71
GLY A  48
ALA A  44
ALA A  53
 None
 1.03A 3sudD-3dzbA:
undetectable		 3sudD-3dzbA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e9y ACETOLACTATE
SYNTHASE,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		5 GLY A 522
GLY A 162
ALA A 155
ALA A 182
ASP A 185
 None
None
None
None
FAB  A 701 ( 4.8A)
 1.03A 3sudD-3e9yA:
undetectable		 3sudD-3e9yA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g7n LIPASE

(Penicillium
expansum) 		PF01764
(Lipase_3) 		6 HIS A 241
VAL A 186
ASP A 188
PHE A 162
ALA A 161
ALA A 136
 SO4  A 259 ( 4.6A)
None
None
None
None
None
 1.20A 3sudD-3g7nA:
undetectable		 3sudD-3g7nA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3it7 PROTEASE LASA

(Pseudomonas
aeruginosa) 		PF01551
(Peptidase_M23) 		5 HIS A  55
GLY A  57
VAL A  52
GLY A  74
ALA A  76
 None
 1.02A 3sudD-3it7A:
undetectable		 3sudD-3it7A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iwa FAD-DEPENDENT
PYRIDINE
NUCLEOTIDE-DISULPHID
E OXIDOREDUCTASE

(Desulfovibrio
vulgaris) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		5 GLN A 402
GLY A 400
VAL A 428
ALA A 419
ALA A 417
 None
 0.93A 3sudD-3iwaA:
undetectable		 3sudD-3iwaA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3khy PROPIONATE KINASE

(Francisella
tularensis) 		PF00871
(Acetate_kinase) 		5 GLY A 265
ALA A 292
ALA A 289
ALA A 282
ASP A 286
 None
 0.98A 3sudD-3khyA:
undetectable		 3sudD-3khyA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lkd TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Streptococcus
thermophilus) 		PF02384
(N6_Mtase)
PF12161
(HsdM_N) 		6 HIS A 342
GLY A 343
GLY A 253
ALA A 228
ALA A 283
ASP A 284
 None
 1.27A 3sudD-3lkdA:
undetectable		 3sudD-3lkdA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lkw FUSION PROTEIN OF
NONSTRUCTURAL
PROTEIN 2B AND
NONSTRUCTURAL
PROTEIN 3

(Dengue virus) 		PF00949
(Peptidase_S7)
PF01002
(Flavi_NS2B) 		5 HIS A 101
VAL A 122
ASP A 125
GLY A 183
ALA A 185
 GOL  A 303 (-3.7A)
None
GOL  A 303 ( 4.7A)
None
None
 0.34A 3sudD-3lkwA:
4.9		 3sudD-3lkwA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mfd D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACB

(Bacillus
subtilis) 		PF00768
(Peptidase_S11)
PF07943
(PBP5_C) 		6 HIS A 156
GLY A 157
ASP A 160
GLY A 116
ALA A  86
SER A  83
 None
 1.25A 3sudD-3mfdA:
undetectable		 3sudD-3mfdA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mkr COATOMER SUBUNIT
EPSILON

(Bos taurus) 		PF04733
(Coatomer_E) 		6 GLY A 195
VAL A 189
GLY A 230
ALA A 228
ALA A 224
ALA A 223
 None
 1.28A 3sudD-3mkrA:
undetectable		 3sudD-3mkrA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mos TRANSKETOLASE

(Homo sapiens) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		5 ASP A 561
GLY A 425
ALA A 430
ALA A 391
ASP A 433
 None
 1.00A 3sudD-3mosA:
undetectable		 3sudD-3mosA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ncy ADIC

(Salmonella
enterica) 		PF13520
(AA_permease_2) 		5 GLY A 175
ALA A 254
ALA A  36
ALA A  37
SER A 195
 None
 1.02A 3sudD-3ncyA:
undetectable		 3sudD-3ncyA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qr3 ENDOGLUCANASE EG-II

(Trichoderma
reesei) 		PF00150
(Cellulase) 		5 GLY A  91
VAL A 141
GLY A  45
PHE A  50
ALA A 294
 None
 0.87A 3sudD-3qr3A:
undetectable		 3sudD-3qr3A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r9u THIOREDOXIN
REDUCTASE

(Campylobacter
jejuni) 		PF07992
(Pyr_redox_2) 		5 ASP A 281
GLY A  37
ALA A 293
ALA A 294
ASP A 296
 FAD  A 501 (-3.3A)
None
FAD  A 501 (-3.4A)
None
None
 0.92A 3sudD-3r9uA:
undetectable		 3sudD-3r9uA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s29 SUCROSE SYNTHASE 1

(Arabidopsis
thaliana) 		PF00534
(Glycos_transf_1)
PF00862
(Sucrose_synth) 		5 HIS A 287
GLY A 288
ASP A 417
GLY A 302
ALA A 439
 FRU  A 902 (-4.0A)
None
None
FRU  A 902 ( 2.2A)
FRU  A 902 ( 3.7A)
 0.90A 3sudD-3s29A:
undetectable		 3sudD-3s29A:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s29 SUCROSE SYNTHASE 1

(Arabidopsis
thaliana) 		PF00534
(Glycos_transf_1)
PF00862
(Sucrose_synth) 		5 HIS A 287
GLY A 288
ASP A 417
GLY A 303
ALA A 439
 FRU  A 902 (-4.0A)
None
None
UDP  A 901 ( 2.9A)
FRU  A 902 ( 3.7A)
 1.01A 3sudD-3s29A:
undetectable		 3sudD-3s29A:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s6l HEP_HAG FAMILY

(Burkholderia
pseudomallei) 		PF05658
(YadA_head)
PF05662
(YadA_stalk) 		6 GLY A  22
GLY A  50
ALA A  39
ALA A  41
ALA A  55
SER A  60
 None
 1.49A 3sudD-3s6lA:
undetectable		 3sudD-3s6lA:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s6l HEP_HAG FAMILY

(Burkholderia
pseudomallei) 		PF05658
(YadA_head)
PF05662
(YadA_stalk) 		6 GLY A  64
GLY A  92
ALA A  81
ALA A  83
ALA A  97
SER A 102
 None
 1.38A 3sudD-3s6lA:
undetectable		 3sudD-3s6lA:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s6l HEP_HAG FAMILY

(Burkholderia
pseudomallei) 		PF05658
(YadA_head)
PF05662
(YadA_stalk) 		5 GLY A  71
GLY A  99
ALA A  88
ALA A  90
ALA A 104
 None
IOD  A 179 ( 3.9A)
None
None
None
 1.03A 3sudD-3s6lA:
undetectable		 3sudD-3s6lA:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s6l HEP_HAG FAMILY

(Burkholderia
pseudomallei) 		PF05658
(YadA_head)
PF05662
(YadA_stalk) 		6 GLY A  78
GLY A 106
ALA A  95
ALA A  97
ALA A 111
SER A 116
 None
 1.44A 3sudD-3s6lA:
undetectable		 3sudD-3s6lA:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1

(Bacillus
anthracis) 		PF00275
(EPSP_synthase) 		5 VAL A  72
GLY A 204
ALA A 202
ALA A 197
ASP A 195
 None
 0.98A 3sudD-3sg1A:
undetectable		 3sudD-3sg1A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sze SERINE PROTEASE ESPP

(Escherichia
coli) 		PF02395
(Peptidase_S6) 		5 HIS A 127
ASP A 156
GLY A 261
ALA A 263
ALA A 296
 None
 0.98A 3sudD-3szeA:
8.5		 3sudD-3szeA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vcy UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE

(Aliivibrio
fischeri) 		PF00275
(EPSP_synthase) 		5 VAL A  71
GLY A 203
ALA A 201
ALA A 196
ASP A 194
 None
 0.99A 3sudD-3vcyA:
undetectable		 3sudD-3vcyA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vex O-CARBAMOYLTRANSFERA
SE TOBZ

(Streptoalloteichus
tenebrarius) 		PF02543
(Carbam_trans_N)
PF16861
(Carbam_trans_C) 		5 GLY A 140
VAL A 161
GLY A  70
ALA A 119
ALA A 120
 CA0  A 602 ( 4.9A)
None
None
None
None
 1.02A 3sudD-3vexA:
undetectable		 3sudD-3vexA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4amm DYNE8

(Micromonospora
chersina) 		PF00698
(Acyl_transf_1) 		5 GLY A 716
VAL A 721
GLY A 837
ALA A 835
ALA A 831
 None
 1.00A 3sudD-4ammA:
undetectable		 3sudD-4ammA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c2l ENDO-XYLOGALACTURONA
N HYDROLASE A

(Aspergillus
tubingensis) 		PF00295
(Glyco_hydro_28) 		5 GLN A 319
ASP A 228
GLY A 284
ALA A 232
SER A 237
 SO4  A1410 ( 4.6A)
SO4  A1410 ( 4.1A)
None
None
None
 0.98A 3sudD-4c2lA:
undetectable		 3sudD-4c2lA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190

(Saccharomyces
cerevisiae) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		5 GLY A1593
GLY A1554
ALA A1558
ALA A1547
ALA A1548
 None
 1.03A 3sudD-4c3hA:
undetectable		 3sudD-4c3hA:
8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dd5 ACETYL-COA
ACETYLTRANSFERASE

(Clostridioides
difficile) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		6 GLY A 257
VAL A 218
GLY A 118
ALA A 259
ALA A  15
ALA A  42
 None
 1.47A 3sudD-4dd5A:
undetectable		 3sudD-4dd5A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dd5 ACETYL-COA
ACETYLTRANSFERASE

(Clostridioides
difficile) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		5 VAL A 208
GLY A 119
ALA A  15
ALA A  14
SER A  13
 None
 0.91A 3sudD-4dd5A:
undetectable		 3sudD-4dd5A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dd5 ACETYL-COA
ACETYLTRANSFERASE

(Clostridioides
difficile) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		5 VAL A 208
GLY A 119
ALA A 258
ALA A  15
SER A  13
 None
 0.98A 3sudD-4dd5A:
undetectable		 3sudD-4dd5A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dt5 ANTIFREEZE PROTEIN

(Rhagium
inquisitor) 		no annotation 5 GLY A  27
GLY A  69
ALA A  51
ALA A  53
ALA A  73
 None
 0.94A 3sudD-4dt5A:
undetectable		 3sudD-4dt5A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f32 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Burkholderia
vietnamiensis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		5 GLY A  30
GLY A 373
ALA A 394
ALA A 365
ASP A 368
 None
 0.96A 3sudD-4f32A:
undetectable		 3sudD-4f32A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4go4 PUTATIVE
GAMMA-HYDROXYMUCONIC
SEMIALDEHYDE
DEHYDROGENASE

(Pseudomonas sp.
WBC-3) 		PF00171
(Aldedh) 		5 GLY A  18
GLY A 203
ALA A  37
ALA A  39
ALA A 211
 None
 1.04A 3sudD-4go4A:
undetectable		 3sudD-4go4A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4it1 PUTATIVE GLUCARATE
DEHYDRATASE

(Pseudomonas
fluorescens) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		5 GLY A 195
ASP A 221
GLY A  23
ALA A  98
SER A 101
 None
MG  A 501 (-2.6A)
None
TLA  A 502 ( 4.8A)
None
 0.89A 3sudD-4it1A:
undetectable		 3sudD-4it1A:
19.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4nwk HCV NS3 1A PROTEASE

(Hepacivirus C) 		PF02907
(Peptidase_S29) 		10 GLN A  41
HIS A  57
GLY A  58
VAL A  78
ASP A  81
GLY A 137
PHE A 154
ALA A 156
ALA A 157
ASP A 168
 2R8  A 301 ( 3.5A)
2R8  A 301 (-3.3A)
2R8  A 301 (-3.5A)
None
2R8  A 301 (-3.6A)
GOL  A 305 ( 3.2A)
2R8  A 301 (-3.7A)
2R8  A 301 (-3.1A)
2R8  A 301 (-3.8A)
2R8  A 301 ( 4.5A)
 0.52A 3sudD-4nwkA:
34.4		 3sudD-4nwkA:
98.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q1t GLUTAMATE 5-KINASE

(Burkholderia
thailandensis) 		PF00696
(AA_kinase)
PF01472
(PUA) 		5 GLY A 198
ALA A 225
ALA A 233
ALA A 168
SER A   8
 None
 1.03A 3sudD-4q1tA:
undetectable		 3sudD-4q1tA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qme AMINOPEPTIDASE N

(Neisseria
meningitidis) 		PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C) 		5 GLY A 395
GLY A 426
ALA A 424
ALA A 420
ALA A 419
 None
 1.01A 3sudD-4qmeA:
undetectable		 3sudD-4qmeA:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea) 		PF00534
(Glycos_transf_1)
PF00862
(Sucrose_synth) 		5 HIS A 273
GLY A 274
ASP A 404
GLY A 288
ALA A 426
 None
 0.93A 3sudD-4rbnA:
undetectable		 3sudD-4rbnA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ru1 MONOSACCHARIDE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT2 FAMILY

(Acidothermus
cellulolyticus) 		PF13407
(Peripla_BP_4) 		5 GLY A 200
ASP A 230
GLY A 164
ALA A 167
ALA A 257
 None
 1.03A 3sudD-4ru1A:
undetectable		 3sudD-4ru1A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wli YUIC

(Bacillus
subtilis) 		PF06725
(3D) 		5 GLY A 115
ALA A 150
ALA A 127
ALA A 128
ASP A 162
 None
None
EDO  A 301 (-3.5A)
None
EDO  A 301 (-3.5A)
 1.03A 3sudD-4wliA:
undetectable		 3sudD-4wliA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN

(Campylobacter
jejuni) 		PF02743
(dCache_1) 		5 GLN A 232
GLY A 236
ALA A 315
ALA A 297
ALA A 298
 None
 0.89A 3sudD-4wy9A:
undetectable		 3sudD-4wy9A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x2x NS6 PROTEASE

(Norwalk virus) 		PF05416
(Peptidase_C37) 		6 HIS A  30
ASP A  54
GLY A 137
ALA A 139
ALA A 159
ALA A 160
 None
 0.64A 3sudD-4x2xA:
7.4		 3sudD-4x2xA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xvx ACYL-[ACYL-CARRIER-P
ROTEIN]
DEHYDROGENASE MBTN

(Mycobacterium
tuberculosis) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		5 ASP A   6
GLY A  47
ALA A  51
ALA A  54
ASP A  56
 None
 1.02A 3sudD-4xvxA:
undetectable		 3sudD-4xvxA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ynn PROTEASE DO

(Legionella
pneumophila) 		PF13180
(PDZ_2)
PF13365
(Trypsin_2) 		5 HIS A  81
ASP A 111
GLY A 188
ALA A 190
ALA A 207
 None
 0.29A 3sudD-4ynnA:
8.5		 3sudD-4ynnA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yzi SENSORY OPSIN
A,ARCHAEAL-TYPE
OPSIN 2

(Chlamydomonas
reinhardtii) 		PF01036
(Bac_rhodopsin) 		5 HIS A 288
GLY A 287
GLY A 272
PHE A 269
ALA A 206
 None
OLA  A 406 (-3.5A)
None
RET  A 401 ( 4.4A)
None
 1.02A 3sudD-4yziA:
undetectable		 3sudD-4yziA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d4k POLYMERIC
IMMUNOGLOBULIN
RECEPTOR

(Homo sapiens) 		PF07686
(V-set) 		5 GLY A  45
VAL A 124
ASP A 125
ALA A 240
SER A 289
 None
 1.02A 3sudD-5d4kA:
undetectable		 3sudD-5d4kA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e6k POLYKETIDE SYNTHASE
PKSL

(Bacillus
subtilis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		5 GLN A 355
GLY A  12
GLY A   9
ALA A 101
PHE A 102
 None
 0.94A 3sudD-5e6kA:
undetectable		 3sudD-5e6kA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eny POLYKETIDE SYNTHASE
PKSL

(Bacillus
subtilis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		5 GLN A 355
GLY A  12
GLY A   9
ALA A 101
PHE A 102
 None
 0.93A 3sudD-5enyA:
undetectable		 3sudD-5enyA:
13.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5eqq NS3 PROTEASE

(Hepacivirus C) 		PF02907
(Peptidase_S29) 		11 GLN A1041
HIS A1057
GLY A1058
VAL A1078
ASP A1081
GLY A1137
ALA A1139
PHE A1154
ALA A1156
ALA A1157
ASP A1168
 5RS  A1203 (-2.9A)
5RS  A1203 (-2.5A)
5RS  A1203 ( 2.9A)
5RS  A1203 (-3.9A)
5RS  A1203 (-3.5A)
5RS  A1203 (-3.2A)
5RS  A1203 (-3.4A)
5RS  A1203 (-3.3A)
5RS  A1203 (-2.9A)
5RS  A1203 (-3.5A)
5RS  A1203 ( 4.0A)
 0.30A 3sudD-5eqqA:
34.5		 3sudD-5eqqA:
94.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ewq AMIDASE

(Bacillus
anthracis) 		PF01425
(Amidase) 		5 GLY A 230
GLY A 245
ALA A 243
ALA A 290
ALA A 296
 None
 1.03A 3sudD-5ewqA:
undetectable		 3sudD-5ewqA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ewq AMIDASE

(Bacillus
anthracis) 		PF01425
(Amidase) 		5 GLY A 245
ALA A 243
ALA A 290
ALA A 296
ASP A 295
 None
 1.02A 3sudD-5ewqA:
undetectable		 3sudD-5ewqA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fjj BETA-GLUCOSIDASE

(Aspergillus
oryzae) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		5 GLY A  39
GLY A 273
ALA A 753
ALA A 240
ALA A 237
 None
 0.87A 3sudD-5fjjA:
undetectable		 3sudD-5fjjA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A

(Cellvibrio
japonicus) 		no annotation 6 GLY A 331
GLY A 334
ALA A 348
PHE A 359
ALA A 357
ASP A 356
 None
 1.46A 3sudD-5fkrA:
undetectable		 3sudD-5fkrA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h05 AMYP

(marine
metagenome) 		PF00128
(Alpha-amylase) 		6 GLY A 125
VAL A 219
ALA A 163
ALA A 198
SER A 201
ASP A 196
 None
 1.36A 3sudD-5h05A:
undetectable		 3sudD-5h05A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hm2 3C PROTEINASE

(Foot-and-mouth
disease virus) 		PF00548
(Peptidase_C3) 		5 HIS A  46
ASP A  84
GLY A 161
ALA A 163
ALA A 183
 None
 0.83A 3sudD-5hm2A:
10.4		 3sudD-5hm2A:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jjc CYSTEINE SYNTHASE

(Brucella
abortus) 		PF00291
(PALP) 		5 ASP A 249
GLY A 190
ALA A 192
PHE A 178
ALA A 180
 None
 0.96A 3sudD-5jjcA:
undetectable		 3sudD-5jjcA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m59 PRE-MRNA SPLICING
HELICASE-LIKE
PROTEIN

(Chaetomium
thermophilum) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02889
(Sec63) 		5 GLN A1738
GLY A1741
VAL A1573
ALA A1401
ALA A1400
 None
 1.04A 3sudD-5m59A:
undetectable		 3sudD-5m59A:
8.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5odo ISOMERASE

(Rhodococcus
erythropolis) 		no annotation 5 GLN A 349
VAL A 484
GLY A 345
ALA A 324
SER A 323
 None
 1.02A 3sudD-5odoA:
undetectable		 3sudD-5odoA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w8p HOMOSERINE
O-ACETYLTRANSFERASE

(Mycobacteroides
abscessus) 		PF00561
(Abhydrolase_1) 		5 GLY A 163
GLY A 322
ALA A 184
ALA A 359
ASP A 358
 None
 0.93A 3sudD-5w8pA:
undetectable		 3sudD-5w8pA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wdx JFH-1 NS3

(Hepacivirus C) 		no annotation 8 GLN A  41
HIS A  57
GLY A  58
GLY A 137
PHE A 154
ALA A 156
ALA A 157
ASP A 168
 None
 0.55A 3sudD-5wdxA:
27.6		 3sudD-5wdxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wdx JFH-1 NS3

(Hepacivirus C) 		no annotation 8 HIS A  57
GLY A  58
ASP A  81
GLY A 137
PHE A 154
ALA A 156
ALA A 157
ASP A 168
 None
 0.32A 3sudD-5wdxA:
27.6		 3sudD-5wdxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xa2 CYSTEINE SYNTHASE

(Planctopirus
limnophila) 		PF00291
(PALP) 		5 ASP A 238
GLY A 184
ALA A 186
PHE A 172
ALA A 174
 None
 0.96A 3sudD-5xa2A:
undetectable		 3sudD-5xa2A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xw3 O-ACETYLSERINE LYASE

(Bacillus
anthracis) 		PF00291
(PALP) 		5 ASP A 237
GLY A 185
ALA A 187
PHE A 173
ALA A 175
 None
 1.04A 3sudD-5xw3A:
undetectable		 3sudD-5xw3A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyj ACETYL-COA
ACETYLTRANSFERASE

(Saccharomyces
cerevisiae) 		no annotation 6 GLY B 257
VAL B 218
GLY B 116
ALA B 259
ALA B  11
ALA B  38
 None
 1.49A 3sudD-5xyjB:
undetectable		 3sudD-5xyjB:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bj9 ACETYL-COA
ACETYLTRANSFERASE A

(Ascaris suum) 		no annotation 5 GLY A  11
GLY A  39
ALA A  13
ALA A 254
ALA A 253
 None
 0.90A 3sudD-6bj9A:
undetectable		 3sudD-6bj9A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE

(Klebsiella
pneumoniae) 		no annotation 5 GLY A  11
ALA A 245
ALA A 241
ALA A 240
SER A 236
 None
 1.02A 3sudD-6blgA:
undetectable		 3sudD-6blgA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8x MYOSIN II HEAVY
CHAIN FUSED TO
ALPHA-ACTININ 3

(Dictyostelium
discoideum) 		PF00063
(Myosin_head)
PF00435
(Spectrin)
PF02736
(Myosin_N) 		4 PHE A 103
TYR A 110
LEU A  97
ARG A 109
 None
 1.00A 3sudD-1g8xA:
0.0		 3sudD-1g8xA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ioo SF11-RNASE

(Nicotiana alata) 		PF00445
(Ribonuclease_T2) 		4 PHE A  29
TYR A 164
LEU A 111
LYS A 112
 None
None
None
NAG  A 197 (-2.9A)
 1.09A 3sudD-1iooA:
0.0		 3sudD-1iooA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A

(Dictyostelium
discoideum) 		PF00063
(Myosin_head)
PF02736
(Myosin_N) 		4 PHE A 114
TYR A 121
LEU A 108
ARG A 120
 None
 0.82A 3sudD-1jx2A:
0.0		 3sudD-1jx2A:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cw7 ENDONUCLEASE
PI-PKOII

(Thermococcus
kodakarensis) 		PF14528
(LAGLIDADG_3)
PF14890
(Intein_splicing) 		4 PHE A 380
LEU A 282
LYS A 280
ARG A 372
 None
 1.49A 3sudD-2cw7A:
0.0		 3sudD-2cw7A:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2im5 NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE

(Porphyromonas
gingivalis) 		PF04095
(NAPRTase) 		4 PHE A 171
TYR A 131
LEU A 334
ARG A 169
 None
 1.27A 3sudD-2im5A:
undetectable		 3sudD-2im5A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2izw RYEGRASS MOTTLE
VIRUS COAT PROTEIN

(Ryegrass mottle
virus) 		PF00729
(Viral_coat) 		4 PHE A  90
TYR A 115
LEU A 183
ARG A 112
 None
 1.30A 3sudD-2izwA:
0.0		 3sudD-2izwA:
28.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mun MU-SCOLOPTOXIN-SSM6A

(Scolopendra
mutilans) 		no annotation 4 TYR A  29
LEU A  44
LYS A  40
ARG A  19
 None
 1.33A 3sudD-2munA:
undetectable		 3sudD-2munA:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o1t ENDOPLASMIN

(Canis lupus) 		PF00183
(HSP90) 		4 PHE A 718
TYR A 727
LEU A 693
ARG A 724
 None
 1.18A 3sudD-2o1tA:
undetectable		 3sudD-2o1tA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o1v ENDOPLASMIN

(Canis lupus) 		PF00183
(HSP90)
PF02518
(HATPase_c) 		4 PHE A 718
TYR A 727
LEU A 693
ARG A 724
 None
 1.26A 3sudD-2o1vA:
0.0		 3sudD-2o1vA:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y9e MYOSIN-2

(Dictyostelium
discoideum) 		PF00063
(Myosin_head)
PF02736
(Myosin_N) 		4 PHE X 103
TYR X 110
LEU X  97
ARG X 109
 None
 1.09A 3sudD-2y9eX:
2.1		 3sudD-2y9eX:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yne GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE

(Plasmodium
vivax) 		PF01233
(NMT)
PF02799
(NMT_C) 		4 PHE A 140
TYR A 107
LEU A 169
ARG A 104
 None
 1.19A 3sudD-2yneA:
undetectable		 3sudD-2yneA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a27 UNCHARACTERIZED
PROTEIN MJ1557

(Methanocaldococcus
jannaschii) 		PF02475
(Met_10) 		4 PHE A 183
LEU A 160
LYS A 161
ARG A 156
 None
None
None
SAM  A 250 ( 4.7A)
 1.16A 3sudD-3a27A:
undetectable		 3sudD-3a27A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1

(Homo sapiens) 		PF01233
(NMT)
PF02799
(NMT_C) 		4 PHE A 225
TYR A 192
LEU A 254
ARG A 189
 None
 1.27A 3sudD-3iu1A:
undetectable		 3sudD-3iu1A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE

(Bacteroides
thetaiotaomicron) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C) 		4 TYR A 161
LEU A 245
LYS A 242
ARG A  10
 None
 1.10A 3sudD-3k85A:
undetectable		 3sudD-3k85A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE

(Parabacteroides
distasonis) 		PF02769
(AIRS_C) 		4 TYR A  65
LEU A 242
LYS A 243
ARG A 212
 None
None
PEG  A 400 (-3.0A)
None
 1.38A 3sudD-3mdoA:
undetectable		 3sudD-3mdoA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qs1 PLASMEPSIN-1

(Plasmodium
falciparum) 		PF00026
(Asp) 		4 PHE A 174
LEU A 324
LYS A 326
ARG A 307
 None
 1.42A 3sudD-3qs1A:
1.3		 3sudD-3qs1A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wmt PROBABLE FERULOYL
ESTERASE B-1

(Aspergillus
oryzae) 		PF07519
(Tannase) 		4 PHE A 220
TYR A 194
LEU A 410
ARG A 117
 None
 1.24A 3sudD-3wmtA:
0.6		 3sudD-3wmtA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c00 TRANSLOCATION AND
ASSEMBLY MODULE TAMA

(Escherichia
coli) 		PF01103
(Bac_surface_Ag)
PF07244
(POTRA)
PF17243
(POTRA_TamA_1) 		4 PHE A 429
TYR A 415
LEU A 499
LYS A 498
 None
 1.39A 3sudD-4c00A:
undetectable		 3sudD-4c00A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c2x GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 2

(Homo sapiens) 		PF01233
(NMT)
PF02799
(NMT_C) 		4 PHE A 225
TYR A 192
LEU A 254
ARG A 189
 None
 1.35A 3sudD-4c2xA:
undetectable		 3sudD-4c2xA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cgn GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE

(Leishmania
major) 		PF01233
(NMT)
PF02799
(NMT_C) 		4 PHE A 125
TYR A  92
LEU A 175
ARG A  89
 None
 1.20A 3sudD-4cgnA:
undetectable		 3sudD-4cgnA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eqf PEX5-RELATED PROTEIN

(Mus musculus) 		PF13181
(TPR_8)
PF13432
(TPR_16) 		4 PHE A 258
TYR A 251
LEU A 312
ARG A 252
 None
 1.32A 3sudD-4eqfA:
undetectable		 3sudD-4eqfA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4etm LOW MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE YFKJ

(Bacillus
subtilis) 		PF01451
(LMWPc) 		4 PHE A   6
TYR A 114
LEU A   9
ARG A 110
 None
None
PO4  A 201 (-4.2A)
None
 1.17A 3sudD-4etmA:
undetectable		 3sudD-4etmA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gyo RESPONSE REGULATOR
ASPARTATE
PHOSPHATASE J

(Bacillus
subtilis) 		PF13424
(TPR_12) 		4 PHE A 101
TYR A 108
LEU A  96
ARG A  59
 None
 1.35A 3sudD-4gyoA:
undetectable		 3sudD-4gyoA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i9c RESPONSE REGULATOR
ASPARTATE
PHOSPHATASE F

(Bacillus
subtilis) 		PF12895
(ANAPC3)
PF13424
(TPR_12) 		4 PHE A 103
TYR A 110
LEU A  98
ARG A  59
 None
 1.47A 3sudD-4i9cA:
undetectable		 3sudD-4i9cA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4irt UNCHARACTERIZED
PROTEIN

(Bacteroides
ovatus) 		PF15892
(BNR_4) 		4 PHE A 156
TYR A 173
LEU A 187
ARG A 172
 None
 1.32A 3sudD-4irtA:
undetectable		 3sudD-4irtA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4it1 PUTATIVE GLUCARATE
DEHYDRATASE

(Pseudomonas
fluorescens) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 PHE A 187
TYR A 350
LEU A 192
LYS A 191
 None
 1.43A 3sudD-4it1A:
undetectable		 3sudD-4it1A:
19.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4nwk HCV NS3 1A PROTEASE

(Hepacivirus C) 		PF02907
(Peptidase_S29) 		4 PHE A  43
TYR A  56
LEU A 135
ARG A 155
 2R8  A 301 (-4.6A)
None
2R8  A 301 (-4.4A)
2R8  A 301 (-3.6A)
 0.55A 3sudD-4nwkA:
34.4		 3sudD-4nwkA:
98.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ozt ECDYSONE RECEPTOR

(Pediculus
humanus) 		PF00104
(Hormone_recep) 		4 PHE E 345
TYR E 429
LEU E 337
ARG E 379
 None
 1.41A 3sudD-4oztE:
undetectable		 3sudD-4oztE:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uph SULFATASE (SULFURIC
ESTER HYDROLASE)
PROTEIN

(Agrobacterium
tumefaciens) 		PF00884
(Sulfatase)
PF16347
(DUF4976) 		4 TYR A 480
LEU A 492
LYS A 490
ARG A 484
 None
 0.91A 3sudD-4uphA:
undetectable		 3sudD-4uphA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w7s PRE-MRNA-SPLICING
ATP-DEPENDENT RNA
HELICASE PRP28

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 PHE A 217
LEU A 229
LYS A 227
ARG A 202
 None
None
None
P6G  A 604 (-3.6A)
 1.48A 3sudD-4w7sA:
undetectable		 3sudD-4w7sA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yg8 CHITIN BIOSYNTHESIS
PROTEIN CHS5
CHITIN BIOSYNTHESIS
PROTEIN CHS6

(Saccharomyces
cerevisiae) 		PF00533
(BRCT)
PF09295
(ChAPs)
PF16893
(fn3_2) 		4 TYR B 353
LEU A  71
LYS A  69
ARG B 350
 None
 1.47A 3sudD-4yg8B:
undetectable		 3sudD-4yg8B:
13.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5eqq NS3 PROTEASE

(Hepacivirus C) 		PF02907
(Peptidase_S29) 		5 PHE A1043
TYR A1056
LEU A1135
LYS A1136
ARG A1155
 5RS  A1203 (-4.3A)
SO4  A1201 ( 4.5A)
5RS  A1203 (-4.2A)
5RS  A1203 (-4.8A)
5RS  A1203 (-4.8A)
 0.31A 3sudD-5eqqA:
34.5		 3sudD-5eqqA:
94.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hs1 LANOSTEROL 14-ALPHA
DEMETHYLASE

(Saccharomyces
cerevisiae) 		PF00067
(p450) 		4 PHE A 111
TYR A 404
LEU A 117
LYS A 116
 None
 1.20A 3sudD-5hs1A:
undetectable		 3sudD-5hs1A:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mul NEURAMINIDASE

(Bacteroides
thetaiotaomicron) 		PF15892
(BNR_4) 		4 PHE A 156
TYR A 173
LEU A 187
ARG A 172
 None
 1.43A 3sudD-5mulA:
undetectable		 3sudD-5mulA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ty7 PENICILLIN-BINDING
PROTEIN 4

(Staphylococcus
aureus) 		no annotation 4 PHE A 243
TYR A 239
LEU A 258
LYS A 259
 None
None
None
NFF  A 401 ( 4.8A)
 1.49A 3sudD-5ty7A:
undetectable		 3sudD-5ty7A:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w6l RTX
REPEAT-CONTAINING
CYTOTOXIN

(Vibrio
vulnificus) 		no annotation 4 TYR A3786
LEU A3958
LYS A3959
ARG A3933
 TYR  A3786 ( 1.3A)
LEU  A3958 ( 0.6A)
LYS  A3959 ( 0.0A)
ARG  A3933 ( 0.6A)
 1.36A 3sudD-5w6lA:
undetectable		 3sudD-5w6lA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6au6 GUANINE
NUCLEOTIDE-BINDING
PROTEIN G(S) SUBUNIT
ALPHA ISOFORMS SHORT

(Homo sapiens) 		no annotation 4 PHE A 290
TYR A 360
LEU A 297
ARG A 342
 None
 1.48A 3sudD-6au6A:
undetectable		 3sudD-6au6A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ax2 MU-HEXATOXIN-MG2A

(Macrothele
gigas) 		no annotation 4 TYR A  25
LEU A  15
LYS A  16
ARG A  35
 None
 1.31A 3sudD-6ax2A:
undetectable		 3sudD-6ax2A:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f91 PUTATIVE
ALPHA-1,2-MANNOSIDAS
E

(Bacteroides
thetaiotaomicron) 		no annotation 4 PHE A 138
TYR A 116
LEU A 268
ARG A 274
 None
 1.46A 3sudD-6f91A:
undetectable		 3sudD-6f91A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gww PEROXIREDOXIN

(Sulfolobus
islandicus) 		no annotation 4 PHE A  98
TYR A  54
LEU A  66
LYS A  64
 None
 1.42A 3sudD-6gwwA:
undetectable		 3sudD-6gwwA:
20.13