SIMILAR PATTERNS OF AMINO ACIDS FOR 3SUD_A_SUEA1201_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c3l | SUBTILISIN-CARLSBERG (Bacilluslicheniformis) |
PF00082(Peptidase_S8) | 5 | GLY A 7GLY A 83ALA A 230ALA A 232SER A 236 | None | 1.09A | 3sudA-1c3lA:undetectable | 3sudA-1c3lA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cc1 | HYDROGENASE (LARGESUBUNIT) (Desulfomicrobiumbaculatum) |
PF00374(NiFeSe_Hases) | 5 | GLN L 111ASP L 490PHE L 117ALA L 121ALA L 122 | None | 1.10A | 3sudA-1cc1L:undetectable | 3sudA-1cc1L:17.49 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1cu1 | PROTEIN(PROTEASE/HELICASENS3) (Hepacivirus C) |
PF02907(Peptidase_S29)PF07652(Flavi_DEAD) | 9 | GLN A 41HIS A 57GLY A 58ASP A 81ARG A 123GLY A 137PHE A 154ALA A 156ALA A 157 | None | 0.54A | 3sudA-1cu1A:34.6 | 3sudA-1cu1A:80.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e12 | HALORHODOPSIN (Halobacteriumsalinarum) |
PF01036(Bac_rhodopsin) | 5 | GLY A 124ALA A 127PHE A 196ALA A 184SER A 177 | None | 1.05A | 3sudA-1e12A:undetectable | 3sudA-1e12A:24.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1efp | PROTEIN (ELECTRONTRANSFERFLAVOPROTEIN) (Paracoccusdenitrificans) |
PF00766(ETF_alpha)PF01012(ETF) | 5 | GLN A 240HIS A 264GLY A 242GLY A 224ALA A 255 | FAD A 399 (-3.9A)FAD A 399 (-3.9A)FAD A 399 (-3.1A)NoneNone | 1.08A | 3sudA-1efpA:undetectable | 3sudA-1efpA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1efv | ELECTRON TRANSFERFLAVOPROTEIN (Homo sapiens) |
PF00766(ETF_alpha)PF01012(ETF) | 5 | GLN A 262HIS A 286GLY A 264GLY A 246ALA A 277 | FAD A 599 (-3.8A)FAD A 599 (-3.8A)FAD A 599 (-3.1A)NoneNone | 1.04A | 3sudA-1efvA:undetectable | 3sudA-1efvA:23.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eyy | ALDEHYDEDEHYDROGENASE (Vibrio harveyi) |
PF00171(Aldedh) | 5 | GLY A 156ALA A 160PHE A 101ALA A 469SER A 462 | None | 1.08A | 3sudA-1eyyA:undetectable | 3sudA-1eyyA:17.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gpe | PROTEIN (GLUCOSEOXIDASE) (Penicilliumamagasakiense) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 5 | GLY A 350GLY A 161ALA A 160ALA A 156ALA A 155 | None | 0.99A | 3sudA-1gpeA:undetectable | 3sudA-1gpeA:17.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gz4 | NAD-DEPENDENT MALICENZYME (Homo sapiens) |
PF00390(malic)PF03949(Malic_M) | 5 | GLY A 290GLY A 463ALA A 444PHE A 443ALA A 418 | None | 1.09A | 3sudA-1gz4A:undetectable | 3sudA-1gz4A:17.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hpg | GLUTAMIC ACIDSPECIFIC PROTEASE (Streptomycesgriseus) |
no annotation | 5 | HIS A 57ASP A 102GLY A 193ALA A 226SER A 225 | None | 0.95A | 3sudA-1hpgA:11.1 | 3sudA-1hpgA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mhz | METHANEMONOOXYGENASEHYDROXYLASE (Methylosinustrichosporium) |
PF02332(Phenol_Hydrox) | 5 | GLY D 167ASP D 164ARG D 502GLY D 357ALA D 359 | None | 1.08A | 3sudA-1mhzD:undetectable | 3sudA-1mhzD:16.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ns3 | NS3 PROTEASE (Hepacivirus C) |
PF02907(Peptidase_S29) | 8 | GLN A 41HIS A 57GLY A 58ASP A 81ARG A 123PHE A 154ALA A 156ALA A 157 | None | 0.78A | 3sudA-1ns3A:30.5 | 3sudA-1ns3A:77.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ns3 | NS3 PROTEASE (Hepacivirus C) |
PF02907(Peptidase_S29) | 8 | HIS A 57GLY A 58ASP A 81ARG A 123GLY A 137PHE A 154ALA A 156ALA A 157 | None | 0.55A | 3sudA-1ns3A:30.5 | 3sudA-1ns3A:77.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p9h | INVASIN (Yersiniaenterocolitica) |
PF05658(YadA_head)PF05662(YadA_stalk) | 5 | GLY A 69GLY A 97ALA A 86ALA A 88ALA A 102 | None | 1.04A | 3sudA-1p9hA:undetectable | 3sudA-1p9hA:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pgj | 6-PHOSPHOGLUCONATEDEHYDROGENASE (Trypanosomabrucei) |
PF00393(6PGD)PF03446(NAD_binding_2) | 5 | GLN A 375ALA A 141PHE A 142ALA A 162ALA A 161 | None | 1.08A | 3sudA-1pgjA:undetectable | 3sudA-1pgjA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1su7 | CARBON MONOXIDEDEHYDROGENASE 2 (Carboxydothermushydrogenoformans) |
PF03063(Prismane) | 5 | GLY A 581GLY A 445ALA A 559ALA A 566SER A 216 | NoneNFS A 639 (-3.6A)NoneNoneNone | 1.06A | 3sudA-1su7A:undetectable | 3sudA-1su7A:14.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1szn | ALPHA-GALACTOSIDASE (Trichodermareesei) |
PF16499(Melibiase_2) | 5 | GLY A 66ASP A 117GLY A 62ALA A 109ALA A 102 | None | 1.07A | 3sudA-1sznA:undetectable | 3sudA-1sznA:15.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x0l | HOMOISOCITRATEDEHYDROGENASE (Thermusthermophilus) |
PF00180(Iso_dh) | 5 | GLY A 14ARG A 103GLY A 261ALA A 276ALA A 244 | None | 0.91A | 3sudA-1x0lA:undetectable | 3sudA-1x0lA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xqw | PROLINEIMINOPEPTIDASE (Thermoplasmaacidophilum) |
PF00561(Abhydrolase_1) | 5 | HIS A 271ASP A 244GLY A 36ALA A 105SER A 47 | LEU A 301 (-3.4A)NoneLEU A 301 (-3.2A)PHE A 300 ( 3.0A)None | 1.06A | 3sudA-1xqwA:undetectable | 3sudA-1xqwA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aw5 | NADP-DEPENDENT MALICENZYME (Homo sapiens) |
PF00390(malic)PF03949(Malic_M) | 5 | GLY A 280GLY A 450ALA A 431PHE A 430ALA A 405 | None | 1.05A | 3sudA-2aw5A:undetectable | 3sudA-2aw5A:17.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dph | FORMALDEHYDEDISMUTASE (Pseudomonasputida) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | GLY A 296ARG A 206GLY A 182ALA A 205ALA A 210 | None | 1.07A | 3sudA-2dphA:undetectable | 3sudA-2dphA:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fk5 | FUCULOSE-1-PHOSPHATEALDOLASE (Thermusthermophilus) |
PF00596(Aldolase_II) | 5 | GLY A 27ARG A 144GLY A 152ALA A 155ALA A 145 | None | 0.89A | 3sudA-2fk5A:undetectable | 3sudA-2fk5A:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i3a | N-ACETYL-GAMMA-GLUTAMYL-PHOSPHATEREDUCTASE (Mycobacteriumtuberculosis) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 5 | GLY A 79GLY A 43ALA A 13ALA A 15ALA A 17 | None | 0.93A | 3sudA-2i3aA:undetectable | 3sudA-2i3aA:23.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2isq | CYSTEINE SYNTHASE (Arabidopsisthaliana) |
PF00291(PALP) | 5 | GLY A 225GLY A 267PHE A 295ALA A 273ALA A 274 | PLP A 400 (-3.5A)NoneNoneNoneNone | 1.01A | 3sudA-2isqA:undetectable | 3sudA-2isqA:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iuy | GLYCOSYLTRANSFERASE (Streptomycesviridochromogenes) |
PF00534(Glycos_transf_1) | 6 | GLN A 250GLY A 186GLY A 280ALA A 247ALA A 265SER A 137 | None | 1.38A | 3sudA-2iuyA:undetectable | 3sudA-2iuyA:23.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j4r | EXOPOLYPHOSPHATASE (Aquifexaeolicus) |
PF02541(Ppx-GppA) | 5 | HIS A 232GLY A 233GLY A 208ALA A 126ALA A 123 | None | 1.10A | 3sudA-2j4rA:undetectable | 3sudA-2j4rA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j92 | PICORNAIN 3C (Foot-and-mouthdisease virus) |
PF00548(Peptidase_C3) | 5 | HIS A 46ASP A 84GLY A 161ALA A 163ALA A 183 | None | 0.61A | 3sudA-2j92A:10.2 | 3sudA-2j92A:23.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p4g | HYPOTHETICAL PROTEIN (Corynebacteriumdiphtheriae) |
PF01872(RibD_C) | 5 | GLY A 229GLY A 45ALA A 47ALA A 39SER A 255 | NoneNoneEDO A 280 ( 3.7A)EDO A 280 (-3.5A)None | 1.10A | 3sudA-2p4gA:undetectable | 3sudA-2p4gA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pnc | COPPER AMINEOXIDASE, LIVERISOZYME (Bos taurus) |
PF01179(Cu_amine_oxid)PF02727(Cu_amine_oxidN2)PF02728(Cu_amine_oxidN3) | 5 | GLY A 387ARG A 622GLY A 368ALA A 623SER A 618 | None | 1.05A | 3sudA-2pncA:undetectable | 3sudA-2pncA:12.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q27 | OXALYL-COADECARBOXYLASE (Escherichiacoli) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | GLN A 141GLY A 10ALA A 173ALA A 168SER A 105 | None | 1.09A | 3sudA-2q27A:undetectable | 3sudA-2q27A:17.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uv8 | FATTY ACID SYNTHASESUBUNIT BETA (FAS1) (Saccharomycescerevisiae) |
PF00698(Acyl_transf_1)PF01575(MaoC_dehydratas)PF08354(DUF1729)PF13452(MaoC_dehydrat_N)PF16073(SAT) | 5 | GLY G1653GLY G1607ALA G1655ALA G1598SER G1600 | None | 1.10A | 3sudA-2uv8G:undetectable | 3sudA-2uv8G:6.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uyd | HEMOPHORE HASA (Serratiamarcescens) |
PF06438(HasA) | 5 | GLY X 101GLY X 43ALA X 56PHE X 67ALA X 69 | None | 1.10A | 3sudA-2uydX:undetectable | 3sudA-2uydX:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xqh | IMMUNOGLOBULIN-BINDING PROTEIN EIBD (Escherichiacoli) |
PF05658(YadA_head) | 5 | GLY A 173GLY A 201ALA A 190ALA A 192ALA A 206 | None | 0.98A | 3sudA-2xqhA:undetectable | 3sudA-2xqhA:25.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yg6 | PUTRESCINE OXIDASE (Rhodococcuserythropolis) |
PF01593(Amino_oxidase) | 5 | GLN A 215ARG A 236GLY A 14ALA A 13ALA A 36 | NoneNoneFAD A 600 (-3.6A)NoneFAD A 600 (-3.5A) | 1.06A | 3sudA-2yg6A:undetectable | 3sudA-2yg6A:19.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cwu | DNA-3-METHYLADENINEGLYCOSYLASE 2 (Escherichiacoli) |
PF00730(HhH-GPD)PF06029(AlkA_N) | 5 | ARG A 22ALA A 136ALA A 132ALA A 131SER A 127 | None | 1.04A | 3sudA-3cwuA:undetectable | 3sudA-3cwuA:19.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dtg | BRANCHED-CHAIN AMINOACIDAMINOTRANSFERASE (Mycolicibacteriumsmegmatis) |
PF01063(Aminotran_4) | 5 | GLY A 79ARG A 108GLY A 270ALA A 203ALA A 202 | NoneNonePLP A 369 (-3.4A)NoneNone | 1.08A | 3sudA-3dtgA:undetectable | 3sudA-3dtgA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e1h | PUTATIVEUNCHARACTERIZEDPROTEIN (Neurosporacrassa) |
PF00195(Chal_sti_synt_N)PF02797(Chal_sti_synt_C) | 5 | GLY A 90ALA A 94ALA A 182ALA A 342SER A 340 | None | 0.97A | 3sudA-3e1hA:undetectable | 3sudA-3e1hA:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3euo | TYPE III PENTAKETIDESYNTHASE (Neurosporacrassa) |
PF00195(Chal_sti_synt_N)PF02797(Chal_sti_synt_C) | 5 | GLY A 90ALA A 94ALA A 182ALA A 342SER A 340 | None | 0.95A | 3sudA-3euoA:undetectable | 3sudA-3euoA:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gcw | PROPROTEINCONVERTASESUBTILISIN/KEXINTYPE 9 (Homo sapiens) |
PF00082(Peptidase_S8) | 5 | GLN A 382HIS A 226ASP A 186GLY A 384ALA A 290 | None | 1.07A | 3sudA-3gcwA:undetectable | 3sudA-3gcwA:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ijf | CYTIDINE DEAMINASE (Mycobacteriumtuberculosis) |
PF00383(dCMP_cyt_deam_1) | 5 | GLY X 81GLY X 19ALA X 20ALA X 57ALA X 60 | None | 1.06A | 3sudA-3ijfX:undetectable | 3sudA-3ijfX:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ju8 | SUCCINYLGLUTAMICSEMIALDEHYDEDEHYDROGENASE (Pseudomonasaeruginosa) |
PF00171(Aldedh) | 5 | GLY A 248GLY A 427ALA A 406ALA A 438SER A 440 | NoneNoneNoneSIN A 504 (-3.8A)SO4 A 503 ( 3.7A) | 1.08A | 3sudA-3ju8A:undetectable | 3sudA-3ju8A:18.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nv9 | MALIC ENZYME (Entamoebahistolytica) |
PF00390(malic)PF03949(Malic_M) | 5 | GLY A 406GLY A 205ALA A 204ALA A 199SER A 230 | None | 1.09A | 3sudA-3nv9A:undetectable | 3sudA-3nv9A:18.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rha | PUTRESCINE OXIDASE (Paenarthrobacteraurescens) |
PF01593(Amino_oxidase) | 5 | GLN A 217ARG A 238GLY A 16ALA A 15ALA A 38 | NoneNoneFDA A 483 (-3.3A)NoneFDA A 483 (-3.4A) | 1.05A | 3sudA-3rhaA:undetectable | 3sudA-3rhaA:18.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s29 | SUCROSE SYNTHASE 1 (Arabidopsisthaliana) |
PF00534(Glycos_transf_1)PF00862(Sucrose_synth) | 5 | HIS A 287GLY A 288ASP A 417GLY A 302ALA A 439 | FRU A 902 (-4.0A)NoneNoneFRU A 902 ( 2.2A)FRU A 902 ( 3.7A) | 0.94A | 3sudA-3s29A:undetectable | 3sudA-3s29A:11.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s6l | HEP_HAG FAMILY (Burkholderiapseudomallei) |
PF05658(YadA_head)PF05662(YadA_stalk) | 5 | GLY A 22GLY A 50ALA A 39ALA A 41ALA A 55 | None | 0.98A | 3sudA-3s6lA:undetectable | 3sudA-3s6lA:24.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s6l | HEP_HAG FAMILY (Burkholderiapseudomallei) |
PF05658(YadA_head)PF05662(YadA_stalk) | 5 | GLY A 29GLY A 57ALA A 46ALA A 48ALA A 62 | None CL A 189 ( 4.0A)NoneNoneNone | 1.04A | 3sudA-3s6lA:undetectable | 3sudA-3s6lA:24.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s6l | HEP_HAG FAMILY (Burkholderiapseudomallei) |
PF05658(YadA_head)PF05662(YadA_stalk) | 5 | GLY A 64GLY A 92ALA A 81ALA A 83ALA A 97 | None | 0.88A | 3sudA-3s6lA:undetectable | 3sudA-3s6lA:24.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s6l | HEP_HAG FAMILY (Burkholderiapseudomallei) |
PF05658(YadA_head)PF05662(YadA_stalk) | 5 | GLY A 71GLY A 99ALA A 88ALA A 90ALA A 104 | NoneIOD A 179 ( 3.9A)NoneNoneNone | 0.98A | 3sudA-3s6lA:undetectable | 3sudA-3s6lA:24.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sze | SERINE PROTEASE ESPP (Escherichiacoli) |
PF02395(Peptidase_S6) | 5 | HIS A 127ASP A 156GLY A 261ALA A 263ALA A 296 | None | 0.98A | 3sudA-3szeA:8.5 | 3sudA-3szeA:11.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tbh | O-ACETYL SERINESULFHYDRYLASE (Leishmaniadonovani) |
PF00291(PALP) | 5 | ASP A 246GLY A 193ALA A 195PHE A 181ALA A 183 | None | 1.03A | 3sudA-3tbhA:undetectable | 3sudA-3tbhA:23.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tt6 | ATP-DEPENDENT CLPPROTEASE PROTEOLYTICSUBUNIT (Bacillussubtilis) |
PF00574(CLP_protease) | 5 | GLY A 106ALA A 104ALA A 100ALA A 95SER A 65 | None | 1.05A | 3sudA-3tt6A:undetectable | 3sudA-3tt6A:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v76 | FLAVOPROTEIN (Sinorhizobiummeliloti) |
PF03486(HI0933_like) | 6 | GLY A 17GLY A 367ALA A 406ALA A 408ALA A 75SER A 74 | NoneFDA A 547 (-3.5A)FDA A 547 ( 3.7A)NoneNoneNone | 1.43A | 3sudA-3v76A:undetectable | 3sudA-3v76A:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zpc | RIBOFLAVINBIOSYNTHESIS PROTEINRIBD (Acinetobacterbaumannii) |
PF00383(dCMP_cyt_deam_1)PF01872(RibD_C) | 5 | ASP A 162ARG A 322ALA A 321ALA A 168SER A 169 | None | 0.87A | 3sudA-3zpcA:undetectable | 3sudA-3zpcA:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zu0 | NAD NUCLEOTIDASE (Haemophilusinfluenzae) |
PF00149(Metallophos)PF02872(5_nucleotid_C) | 5 | GLY A 536ARG A 437GLY A 493ALA A 416ALA A 433 | NoneA12 A1598 (-2.6A)NoneNoneNone | 1.09A | 3sudA-3zu0A:undetectable | 3sudA-3zu0A:14.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4da1 | PROTEIN PHOSPHATASE1K, MITOCHONDRIAL (Homo sapiens) |
PF00481(PP2C) | 5 | GLY A 130GLY A 265ALA A 134ALA A 190SER A 205 | None | 0.94A | 3sudA-4da1A:undetectable | 3sudA-4da1A:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dt5 | ANTIFREEZE PROTEIN (Rhagiuminquisitor) |
no annotation | 5 | GLY A 27GLY A 69ALA A 51ALA A 53ALA A 73 | None | 0.96A | 3sudA-4dt5A:undetectable | 3sudA-4dt5A:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gji | L-RHAMNOSE ISOMERASE (Pseudomonasstutzeri) |
no annotation | 5 | GLN A 250GLY A 275ARG A 358GLY A 319ALA A 312 | None | 1.03A | 3sudA-4gjiA:undetectable | 3sudA-4gjiA:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4go4 | PUTATIVEGAMMA-HYDROXYMUCONICSEMIALDEHYDEDEHYDROGENASE (Pseudomonas sp.WBC-3) |
PF00171(Aldedh) | 5 | GLY A 18GLY A 203ALA A 37ALA A 39ALA A 211 | None | 1.02A | 3sudA-4go4A:undetectable | 3sudA-4go4A:17.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hxy | PLM1 (Streptomycessp. HK803) |
PF08659(KR) | 5 | GLY A 192ARG A 346GLY A 275ALA A 273ALA A 301 | NoneNoneNDP A 501 (-4.0A)NDP A 501 (-3.9A)None | 1.10A | 3sudA-4hxyA:undetectable | 3sudA-4hxyA:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kzp | OXIDOREDUCTASE,SHORT CHAINDEHYDROGENASE/REDUCTASE FAMILY PROTEIN (Mycolicibacteriumsmegmatis) |
PF00106(adh_short) | 5 | GLY A 98ASP A 101LYS A 73ALA A 47ALA A 43 | None | 0.96A | 3sudA-4kzpA:undetectable | 3sudA-4kzpA:21.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4nwk | HCV NS3 1A PROTEASE (Hepacivirus C) |
PF02907(Peptidase_S29) | 8 | GLN A 41HIS A 57GLY A 58ASP A 81GLY A 137PHE A 154ALA A 156ALA A 157 | 2R8 A 301 ( 3.5A)2R8 A 301 (-3.3A)2R8 A 301 (-3.5A)2R8 A 301 (-3.6A)GOL A 305 ( 3.2A)2R8 A 301 (-3.7A)2R8 A 301 (-3.1A)2R8 A 301 (-3.8A) | 0.20A | 3sudA-4nwkA:34.8 | 3sudA-4nwkA:98.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o8o | ALPHA-L-ARABINOFURANOSIDASE (Streptomycesthermoviolaceus) |
PF03664(Glyco_hydro_62) | 5 | GLY A 340GLY A 74ALA A 75ALA A 77ALA A 126 | None | 1.04A | 3sudA-4o8oA:undetectable | 3sudA-4o8oA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ov6 | PROPROTEINCONVERTASESUBTILISIN/KEXINTYPE 9 (Homo sapiens) |
PF00082(Peptidase_S8) | 5 | GLN B 382HIS B 226ASP B 186GLY B 384ALA B 290 | None | 1.03A | 3sudA-4ov6B:undetectable | 3sudA-4ov6B:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oyy | CUTINASE (Humicolainsolens) |
PF01083(Cutinase) | 5 | GLY A 27GLY A 102ALA A 25ALA A 114SER A 116 | None | 1.10A | 3sudA-4oyyA:undetectable | 3sudA-4oyyA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p98 | EXTRACELLULARSOLUTE-BINDINGPROTEIN (Conexibacterwoesei) |
PF02608(Bmp) | 5 | GLY A 161GLY A 211ALA A 209ALA A 233ALA A 235 | NoneNoneNoneNone BR A 419 ( 4.5A) | 1.06A | 3sudA-4p98A:undetectable | 3sudA-4p98A:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4psd | CARBOHYDRATEESTERASE FAMILY 5 (Trichodermareesei) |
PF01083(Cutinase) | 5 | GLY A 89GLY A 161ALA A 87ALA A 173SER A 175 | None | 0.90A | 3sudA-4psdA:undetectable | 3sudA-4psdA:24.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4psd | CARBOHYDRATEESTERASE FAMILY 5 (Trichodermareesei) |
PF01083(Cutinase) | 5 | GLY A 89GLY A 162ALA A 87ALA A 173SER A 175 | None | 1.01A | 3sudA-4psdA:undetectable | 3sudA-4psdA:24.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qme | AMINOPEPTIDASE N (Neisseriameningitidis) |
PF01433(Peptidase_M1)PF11940(DUF3458)PF17432(DUF3458_C) | 5 | GLY A 395GLY A 426ALA A 424ALA A 420ALA A 419 | None | 1.02A | 3sudA-4qmeA:undetectable | 3sudA-4qmeA:12.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rbn | SUCROSESYNTHASE:GLYCOSYLTRANSFERASES GROUP 1 (Nitrosomonaseuropaea) |
PF00534(Glycos_transf_1)PF00862(Sucrose_synth) | 5 | HIS A 273GLY A 274ASP A 404GLY A 288ALA A 426 | None | 0.94A | 3sudA-4rbnA:undetectable | 3sudA-4rbnA:14.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wy9 | PUTATIVE MCP-TYPESIGNAL TRANSDUCTIONPROTEIN (Campylobacterjejuni) |
PF02743(dCache_1) | 5 | GLN A 232GLY A 236ALA A 315ALA A 297ALA A 298 | None | 0.94A | 3sudA-4wy9A:undetectable | 3sudA-4wy9A:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x2x | NS6 PROTEASE (Norwalk virus) |
PF05416(Peptidase_C37) | 6 | HIS A 30ASP A 54GLY A 137ALA A 139ALA A 159ALA A 160 | None | 0.55A | 3sudA-4x2xA:10.6 | 3sudA-4x2xA:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xeu | TRANSKETOLASE (Pseudomonasaeruginosa) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 6 | GLY A 408ARG A 442PHE A 412ALA A 441ALA A 444SER A 448 | None | 1.36A | 3sudA-4xeuA:undetectable | 3sudA-4xeuA:15.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ynn | PROTEASE DO (Legionellapneumophila) |
PF13180(PDZ_2)PF13365(Trypsin_2) | 5 | HIS A 81ASP A 111GLY A 188ALA A 190ALA A 207 | None | 0.27A | 3sudA-4ynnA:13.0 | 3sudA-4ynnA:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yzi | SENSORY OPSINA,ARCHAEAL-TYPEOPSIN 2 (Chlamydomonasreinhardtii) |
PF01036(Bac_rhodopsin) | 5 | HIS A 288GLY A 287GLY A 272PHE A 269ALA A 206 | NoneOLA A 406 (-3.5A)NoneRET A 401 ( 4.4A)None | 1.07A | 3sudA-4yziA:undetectable | 3sudA-4yziA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zo6 | LIN1840 PROTEIN (Listeriainnocua) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 5 | GLY A 174ALA A 176ALA A 231ALA A 188SER A 136 | None | 1.08A | 3sudA-4zo6A:undetectable | 3sudA-4zo6A:14.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5abj | VP2 (Enterovirus A) |
PF00073(Rhv) | 5 | ARG B 103GLY B 93ALA B 96PHE B 245ALA B 243 | None | 1.03A | 3sudA-5abjB:undetectable | 3sudA-5abjB:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b1h | CYSTATHIONINEBETA-SYNTHASE (Lactobacillusplantarum) |
PF00291(PALP) | 5 | ASP A 235GLY A 183ALA A 185PHE A 171ALA A 173 | None | 1.10A | 3sudA-5b1hA:undetectable | 3sudA-5b1hA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cyk | RIBOSOME BIOGENESISPROTEIN YTM1 (Chaetomiumthermophilum) |
PF00400(WD40)PF08154(NLE) | 5 | HIS A 224GLY A 223ASP A 246ALA A 243ALA A 303 | None | 1.08A | 3sudA-5cykA:undetectable | 3sudA-5cykA:17.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ed1 | DOUBLE-STRANDEDRNA-SPECIFIC EDITASE1 (Homo sapiens) |
PF02137(A_deamin) | 5 | GLY A 354ARG A 348GLY A 333ALA A 347SER A 344 | None G C 5 ( 3.2A)NoneNoneNone | 1.02A | 3sudA-5ed1A:undetectable | 3sudA-5ed1A:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eny | POLYKETIDE SYNTHASEPKSL (Bacillussubtilis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | GLN A 355GLY A 12GLY A 9ALA A 101PHE A 102 | None | 0.96A | 3sudA-5enyA:undetectable | 3sudA-5enyA:13.37 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5eqq | NS3 PROTEASE (Hepacivirus C) |
PF02907(Peptidase_S29) | 11 | GLN A1041HIS A1057GLY A1058ASP A1081ARG A1123LYS A1136GLY A1137ALA A1139PHE A1154ALA A1156ALA A1157 | 5RS A1203 (-2.9A)5RS A1203 (-2.5A)5RS A1203 ( 2.9A)5RS A1203 (-3.5A)5RS A1203 ( 3.3A)5RS A1203 (-4.8A)5RS A1203 (-3.2A)5RS A1203 (-3.4A)5RS A1203 (-3.3A)5RS A1203 (-2.9A)5RS A1203 (-3.5A) | 0.41A | 3sudA-5eqqA:36.0 | 3sudA-5eqqA:94.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ewq | AMIDASE (Bacillusanthracis) |
PF01425(Amidase) | 5 | GLY A 230GLY A 245ALA A 243ALA A 290ALA A 296 | None | 1.07A | 3sudA-5ewqA:undetectable | 3sudA-5ewqA:15.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fjj | BETA-GLUCOSIDASE (Aspergillusoryzae) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 5 | GLY A 39GLY A 273ALA A 753ALA A 240ALA A 237 | None | 0.90A | 3sudA-5fjjA:undetectable | 3sudA-5fjjA:12.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fq6 | SUSC/RAGA FAMILYTONB-LINKED OUTERMEMBRANE PROTEIN (Bacteroidesthetaiotaomicron) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 5 | GLY B 160ALA B 157ALA B 149ALA B 148SER B 590 | None | 1.08A | 3sudA-5fq6B:undetectable | 3sudA-5fq6B:12.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fzp | DISPASEAUTOLYSIS-INDUCINGPROTEIN (Streptomycesmobaraensis) |
no annotation | 5 | GLY A 143ARG A 259GLY A 186ALA A 184ALA A 204 | None | 0.88A | 3sudA-5fzpA:undetectable | 3sudA-5fzpA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hal | UNCHARACTERIZEDPROTEIN (Burkholderiavietnamiensis) |
no annotation | 5 | GLY A 49ALA A 70ALA A 73ALA A 93SER A 94 | None | 0.94A | 3sudA-5halA:undetectable | 3sudA-5halA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hm2 | 3C PROTEINASE (Foot-and-mouthdisease virus) |
PF00548(Peptidase_C3) | 5 | HIS A 46ASP A 84GLY A 161ALA A 163ALA A 183 | None | 0.76A | 3sudA-5hm2A:9.8 | 3sudA-5hm2A:23.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jjc | CYSTEINE SYNTHASE (Brucellaabortus) |
PF00291(PALP) | 5 | ASP A 249GLY A 190ALA A 192PHE A 178ALA A 180 | None | 0.93A | 3sudA-5jjcA:undetectable | 3sudA-5jjcA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k8b | 8-AMINO-3,8-DIDEOXY-ALPHA-D-MANNO-OCTULOSONATE TRANSAMINASE (Shewanellaoneidensis) |
PF01041(DegT_DnrJ_EryC1) | 5 | GLY A 8ALA A 246ALA A 242ALA A 241SER A 237 | None | 1.10A | 3sudA-5k8bA:undetectable | 3sudA-5k8bA:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tr7 | D-ALANYL-D-ALANINECARBOXYPEPTIDASE (Vibrio cholerae) |
PF00768(Peptidase_S11)PF07943(PBP5_C) | 5 | HIS A 48ASP A 46GLY A 250PHE A 279ALA A 247 | None | 1.05A | 3sudA-5tr7A:undetectable | 3sudA-5tr7A:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u3f | BRANCHED-CHAIN-AMINO-ACIDAMINOTRANSFERASE (Mycobacteriumtuberculosis) |
PF01063(Aminotran_4) | 5 | GLY A 79ARG A 108GLY A 270ALA A 203ALA A 202 | 7TS A 400 (-3.1A)None7TS A 400 (-3.4A)NoneNone | 1.03A | 3sudA-5u3fA:undetectable | 3sudA-5u3fA:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vlh | PROPROTEINCONVERTASESUBTILISIN/KEXINTYPE 9 (Homo sapiens) |
PF00082(Peptidase_S8)PF05922(Inhibitor_I9) | 5 | GLN A 382HIS A 226ASP A 186GLY A 384ALA A 290 | None | 1.01A | 3sudA-5vlhA:undetectable | 3sudA-5vlhA:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w8p | HOMOSERINEO-ACETYLTRANSFERASE (Mycobacteroidesabscessus) |
PF00561(Abhydrolase_1) | 5 | GLY A 163ARG A 238GLY A 322ALA A 184ALA A 359 | None | 0.94A | 3sudA-5w8pA:undetectable | 3sudA-5w8pA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wdx | JFH-1 NS3 (Hepacivirus C) |
no annotation | 6 | GLN A 41ARG A 123GLY A 137PHE A 154ALA A 156ALA A 157 | None | 0.58A | 3sudA-5wdxA:27.2 | 3sudA-5wdxA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wdx | JFH-1 NS3 (Hepacivirus C) |
no annotation | 8 | HIS A 57GLY A 58ASP A 81ARG A 123GLY A 137PHE A 154ALA A 156ALA A 157 | None | 0.44A | 3sudA-5wdxA:27.2 | 3sudA-5wdxA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xa2 | CYSTEINE SYNTHASE (Planctopiruslimnophila) |
PF00291(PALP) | 5 | ASP A 238GLY A 184ALA A 186PHE A 172ALA A 174 | None | 0.92A | 3sudA-5xa2A:undetectable | 3sudA-5xa2A:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xw3 | O-ACETYLSERINE LYASE (Bacillusanthracis) |
PF00291(PALP) | 5 | ASP A 237GLY A 185ALA A 187PHE A 173ALA A 175 | None | 1.05A | 3sudA-5xw3A:undetectable | 3sudA-5xw3A:23.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bj9 | ACETYL-COAACETYLTRANSFERASE A (Ascaris suum) |
no annotation | 5 | GLY A 11GLY A 39ALA A 13ALA A 254ALA A 253 | None | 0.89A | 3sudA-6bj9A:undetectable | 3sudA-6bj9A:19.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6blg | DTDP-4-AMINO-4,6-DIDEOXYGALACTOSETRANSAMINASE (Klebsiellapneumoniae) |
no annotation | 5 | GLY A 11ALA A 245ALA A 241ALA A 240SER A 236 | None | 0.94A | 3sudA-6blgA:undetectable | 3sudA-6blgA:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6btm | ALTERNATIVE COMPLEXIII SUBUNIT B (Flavobacteriumjohnsoniae) |
no annotation | 5 | GLY B 974ASP B 759ARG B1017ALA B 266ALA B 292 | None | 0.94A | 3sudA-6btmB:undetectable | 3sudA-6btmB:18.95 |