SIMILAR PATTERNS OF AMINO ACIDS FOR 3SJ4_X_DXCX75
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1by7 | PROTEIN (PLASMINOGENACTIVATORINHIBITOR-2) (Homo sapiens) |
PF00079(Serpin) | 5 | ILE A 114LEU A 407PHE A 204LYS A 207GLY A 206 | None | 1.47A | 3sj4X-1by7A:undetectable | 3sj4X-1by7A:11.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ckm | MRNA CAPPING ENZYME (ParameciumbursariaChlorella virus1) |
PF01331(mRNA_cap_enzyme)PF03919(mRNA_cap_C) | 5 | ILE A 26LEU A 113ILE A 184PHE A 143GLY A 130 | None | 1.15A | 3sj4X-1ckmA:undetectable | 3sj4X-1ckmA:12.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eep | INOSINE5'-MONOPHOSPHATEDEHYDROGENASE (Borreliellaburgdorferi) |
PF00478(IMPDH) | 5 | ILE A 242LYS A 220ILE A 259MET A 283GLY A 263 | NoneNoneNoneNoneSO4 A 600 (-3.4A) | 1.37A | 3sj4X-1eepA:undetectable | 3sj4X-1eepA:11.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f89 | 32.5 KDA PROTEINYLR351C (Saccharomycescerevisiae) |
PF00795(CN_hydrolase) | 5 | ILE A 11LEU A 7ILE A 190LYS A 184GLY A 185 | None | 1.27A | 3sj4X-1f89A:undetectable | 3sj4X-1f89A:14.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i8q | HYALURONATE LYASE (Streptococcusagalactiae) |
PF02278(Lyase_8)PF02884(Lyase_8_C)PF08124(Lyase_8_N) | 5 | ILE A 767LEU A 633ILE A 676MET A 673GLY A 672 | None | 1.40A | 3sj4X-1i8qA:undetectable | 3sj4X-1i8qA:6.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kr4 | PROTEIN TM1056, CUTA (Thermotogamaritima) |
PF03091(CutA1) | 5 | ILE A 86LEU A 75LYS A 62ILE A 8PHE A 61 | None | 1.40A | 3sj4X-1kr4A:undetectable | 3sj4X-1kr4A:18.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1leh | LEUCINEDEHYDROGENASE (Lysinibacillussphaericus) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 5 | ILE A 360LEU A 298ILE A 292LYS A 80GLY A 41 | None | 1.47A | 3sj4X-1lehA:undetectable | 3sj4X-1lehA:10.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o5j | PERIPLASMIC DIVALENTCATION TOLERANCEPROTEIN (Thermotogamaritima) |
PF03091(CutA1) | 5 | ILE A 80LEU A 69LYS A 56ILE A 2PHE A 55 | None | 1.33A | 3sj4X-1o5jA:undetectable | 3sj4X-1o5jA:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r6z | CHIMERA OFMALTOSE-BINDINGPERIPLASMIC PROTEINAND ARGONAUTE 2 (Escherichiacoli;Drosophilamelanogaster) |
no annotation | 5 | ILE P 131LEU P 197LYS P 255ILE P 225GLY P 190 | None | 1.32A | 3sj4X-1r6zP:undetectable | 3sj4X-1r6zP:10.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rbl | RIBULOSE 1,5BISPHOSPHATECARBOXYLASE/OXYGENASE (LARGE CHAIN) (Synechococcuselongatus) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 5 | ILE A 309LEU A 314ILE A 116PHE A 274GLY A 273 | None | 1.09A | 3sj4X-1rblA:undetectable | 3sj4X-1rblA:9.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w27 | PHENYLALANINEAMMONIA-LYASE 1 (Petroselinumcrispum) |
PF00221(Lyase_aromatic) | 5 | ILE A 182LEU A 216ILE A 190PHE A 238GLY A 245 | None | 1.12A | 3sj4X-1w27A:undetectable | 3sj4X-1w27A:7.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w27 | PHENYLALANINEAMMONIA-LYASE 1 (Petroselinumcrispum) |
PF00221(Lyase_aromatic) | 5 | ILE A 182LEU A 216ILE A 190PHE A 238GLY A 246 | None | 1.23A | 3sj4X-1w27A:undetectable | 3sj4X-1w27A:7.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w2w | 5-METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE5-METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE (Saccharomycescerevisiae;Saccharomycescerevisiae) |
PF01008(IF-2B)PF01008(IF-2B) | 5 | ILE B 282LEU B 407LYS A 153ILE B 391PHE B 397 | None | 1.20A | 3sj4X-1w2wB:undetectable | 3sj4X-1w2wB:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xsa | BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE (Homo sapiens) |
PF00293(NUDIX) | 5 | ILE A 78LEU A 147LYS A 47ILE A 15PHE A 31 | None | 1.41A | 3sj4X-1xsaA:undetectable | 3sj4X-1xsaA:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bmf | RNA HELICASE (Dengue virus) |
PF07652(Flavi_DEAD) | 5 | ILE A 383LEU A 385ILE A 395PHE A 390GLY A 414 | None | 1.44A | 3sj4X-2bmfA:undetectable | 3sj4X-2bmfA:9.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cyc | TYROSYL-TRNASYNTHETASE (Pyrococcushorikoshii) |
PF00579(tRNA-synt_1b) | 5 | ILE A 270LEU A 351ILE A 297MET A 53GLY A 49 | None | 1.19A | 3sj4X-2cycA:undetectable | 3sj4X-2cycA:11.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eb5 | 2-OXO-HEPT-3-ENE-1,7-DIOATE HYDRATASE (Escherichiacoli) |
PF01557(FAA_hydrolase) | 5 | ILE A 135LEU A 173ILE A 235MET A 87GLY A 170 | None | 1.45A | 3sj4X-2eb5A:undetectable | 3sj4X-2eb5A:11.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ec5 | DERMONECROTIC TOXIN (Pasteurellamultocida) |
PF11647(MLD) | 5 | ILE A 999LEU A1030ILE A 939PHE A1037GLY A 911 | None | 1.29A | 3sj4X-2ec5A:undetectable | 3sj4X-2ec5A:6.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fhk | FORMYLMETHANOFURAN--TETRAHYDROMETHANOPTERINFORMYLTRANSFERASE (Methanopyruskandleri) |
PF01913(FTR)PF02741(FTR_C) | 5 | ILE A 25ILE A 77PHE A 158LYS A 123GLY A 121 | NoneNoneNoneMFN A 600 (-4.0A)None | 1.41A | 3sj4X-2fhkA:undetectable | 3sj4X-2fhkA:13.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gnx | HYPOTHETICAL PROTEIN (Mus musculus) |
PF09404(DUF2003) | 5 | ILE A 404LEU A 426LYS A 412ILE A 420PHE A 422 | None | 1.27A | 3sj4X-2gnxA:undetectable | 3sj4X-2gnxA:14.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gti | REPLICASEPOLYPROTEIN 1AB (Murinecoronavirus) |
PF06471(NSP11) | 5 | ILE A 142LEU A 125ILE A 137PHE A 128LYS A 177 | NoneSO4 A 503 (-4.0A)NoneNoneNone | 1.46A | 3sj4X-2gtiA:undetectable | 3sj4X-2gtiA:11.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hcz | BETA-EXPANSIN 1A (Zea mays) |
PF01357(Pollen_allerg_1)PF03330(DPBB_1) | 5 | ILE X 152LEU X 161LYS X 225PHE X 210GLY X 208 | None | 1.01A | 3sj4X-2hczX:undetectable | 3sj4X-2hczX:17.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i7t | CLEAVAGE ANDPOLYADENYLATIONSPECIFICITY FACTOR73 KDA SUBUNIT (Homo sapiens) |
PF00753(Lactamase_B)PF07521(RMMBL)PF10996(Beta-Casp) | 5 | ILE A 167LEU A 68ILE A 29LYS A 90GLY A 91 | None | 1.44A | 3sj4X-2i7tA:undetectable | 3sj4X-2i7tA:8.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ory | LIPASE (Photobacteriumsp. M37) |
PF01764(Lipase_3) | 5 | LEU A 41LYS A 167PHE A 12MET A 9LYS A 5 | None | 1.29A | 3sj4X-2oryA:undetectable | 3sj4X-2oryA:11.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2peg | HEMOGLOBIN SUBUNITBETA (Trematomusbernacchii) |
PF00042(Globin) | 5 | ILE B 110LEU B 134PHE B 133MET B 78GLY B 74 | None | 1.32A | 3sj4X-2pegB:undetectable | 3sj4X-2pegB:17.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pfk | 6-PHOSPHOFRUCTOKINASE ISOZYME I (Escherichiacoli) |
PF00365(PFK) | 5 | ILE A 234LEU A 201ILE A 217PHE A 188GLY A 208 | None | 1.36A | 3sj4X-2pfkA:undetectable | 3sj4X-2pfkA:11.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qe6 | UNCHARACTERIZEDPROTEIN TFU_2867 (Thermobifidafusca) |
PF04672(Methyltransf_19) | 5 | ILE A 160LEU A 185ILE A 268PHE A 233GLY A 231 | None | 1.16A | 3sj4X-2qe6A:undetectable | 3sj4X-2qe6A:12.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qv0 | PROTEIN MRKE (Klebsiellapneumoniae) |
PF00072(Response_reg) | 5 | ILE A 125LEU A 99ILE A 113PHE A 89GLY A 87 | None | 0.96A | 3sj4X-2qv0A:undetectable | 3sj4X-2qv0A:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wmy | PUTATIVE ACIDPHOSPHATASE WZB (Escherichiacoli) |
PF01451(LMWPc) | 5 | ILE A 9LEU A 27ILE A 12PHE A 108GLY A 109 | None | 1.17A | 3sj4X-2wmyA:undetectable | 3sj4X-2wmyA:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xn6 | THYROXINE-BINDINGGLOBULIN (Homo sapiens) |
PF00079(Serpin) | 5 | ILE A 116LEU A 114LYS A 125PHE A 126GLY A 63 | None | 1.10A | 3sj4X-2xn6A:undetectable | 3sj4X-2xn6A:14.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xz3 | MALTOSE ABCTRANSPORTERPERIPLASMIC PROTEIN,ENVELOPEGLYCOPROTEIN (Escherichiacoli;Bovine leukemiavirus) |
PF00429(TLV_coat)PF13416(SBP_bac_8) | 5 | ILE A 158LEU A 224LYS A 282ILE A 252GLY A 217 | None | 1.23A | 3sj4X-2xz3A:undetectable | 3sj4X-2xz3A:10.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3any | ETHANOLAMINEAMMONIA-LYASE HEAVYCHAIN (Escherichiacoli) |
PF06751(EutB) | 5 | ILE A 218LEU A 181ILE A 209MET A 394GLY A 393 | None | 1.27A | 3sj4X-3anyA:undetectable | 3sj4X-3anyA:10.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bm3 | PSPGI RESTRICTIONENDONUCLEASE (Pyrococcus sp.GI-H) |
PF09019(EcoRII-C) | 5 | ILE A 253LEU A 112ILE A 140PHE A 139LYS A 160 | None | 1.34A | 3sj4X-3bm3A:undetectable | 3sj4X-3bm3A:12.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cg3 | UPF0100 PROTEINPH0151 (Pyrococcushorikoshii) |
PF13531(SBP_bac_11) | 5 | ILE A 176LEU A 180ILE A 139PHE A 147GLY A 148 | None | 1.41A | 3sj4X-3cg3A:undetectable | 3sj4X-3cg3A:10.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dm0 | MALTOSE-BINDINGPERIPLASMIC PROTEINFUSED WITH RACK1 (Escherichiacoli;Arabidopsisthaliana) |
PF00400(WD40)PF01547(SBP_bac_1) | 5 | ILE A 132LEU A 198LYS A 256ILE A 226GLY A 191 | None | 1.27A | 3sj4X-3dm0A:undetectable | 3sj4X-3dm0A:7.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dpu | RAB FAMILY PROTEIN (Chlorobaculumtepidum) |
PF08477(Roc)PF16095(COR) | 5 | ILE A 555LEU A 538LYS A 486MET A 462GLY A 461 | None | 1.34A | 3sj4X-3dpuA:undetectable | 3sj4X-3dpuA:8.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f3s | LAMBDA-CRYSTALLINHOMOLOG (Homo sapiens) |
PF00725(3HCDH)PF02737(3HCDH_N) | 5 | ILE A 179LEU A 175LYS A 33ILE A 11GLY A 7 | None | 1.08A | 3sj4X-3f3sA:undetectable | 3sj4X-3f3sA:11.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3la4 | UREASE (Canavaliaensiformis) |
PF00449(Urease_alpha)PF00547(Urease_gamma)PF00699(Urease_beta)PF01979(Amidohydro_1) | 5 | ILE A 364LEU A 705LYS A 354ILE A 353GLY A 394 | None | 0.81A | 3sj4X-3la4A:undetectable | 3sj4X-3la4A:6.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mq9 | BONE MARROW STROMALANTIGEN 2 FUSED TOMALTOSE-BINDINGPERIPLASMIC PROTEIN (Escherichiacoli;Homo sapiens) |
PF13416(SBP_bac_8)PF16716(BST2) | 5 | ILE A 132LEU A 198LYS A 256ILE A 226GLY A 191 | None | 1.16A | 3sj4X-3mq9A:undetectable | 3sj4X-3mq9A:10.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n93 | MALTOSE BINDINGPROTEIN-CRFR2 ALPHA (Homo sapiens) |
PF02793(HRM)PF13416(SBP_bac_8) | 5 | ILE A-238LEU A-172LYS A-114ILE A-144GLY A-179 | None | 1.22A | 3sj4X-3n93A:undetectable | 3sj4X-3n93A:9.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ns1 | XANTHINEDEHYDROGENASE/OXIDASE (Bos taurus) |
PF00941(FAD_binding_5)PF03450(CO_deh_flav_C) | 5 | ILE B 407LEU B 372LYS B 256ILE B 403LYS B 395 | NoneNoneFAD B 606 (-3.9A)FAD B 606 ( 4.1A)None | 1.28A | 3sj4X-3ns1B:undetectable | 3sj4X-3ns1B:11.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oai | MALTOSE-BINDINGPERIPLASMIC PROTEIN,MYELIN PROTEIN P0 (Escherichiacoli;Homo sapiens) |
PF07686(V-set)PF13416(SBP_bac_8) | 5 | ILE A 132LEU A 198LYS A 256ILE A 226GLY A 191 | None | 1.26A | 3sj4X-3oaiA:undetectable | 3sj4X-3oaiA:8.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ob4 | MALTOSE ABCTRANSPORTERPERIPLASMIC PROTEIN,ARAH 2 (Escherichiacoli;Arachisduranensis) |
PF00234(Tryp_alpha_amyl)PF13416(SBP_bac_8) | 5 | ILE A 132LEU A 198LYS A 256ILE A 226GLY A 191 | None | 1.23A | 3sj4X-3ob4A:undetectable | 3sj4X-3ob4A:9.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r89 | OROTIDINE5'-PHOSPHATEDECARBOXYLASE (Anaerococcusprevotii) |
PF00215(OMPdecase) | 5 | ILE A 59LEU A 7ILE A 221MET A 217GLY A 196 | None | 1.30A | 3sj4X-3r89A:undetectable | 3sj4X-3r89A:14.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v4b | STARVATION SENSINGPROTEIN RSPA (Cellvibriojaponicus) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ILE A 52LEU A 20ILE A 66MET A 83GLY A 82 | None | 1.30A | 3sj4X-3v4bA:undetectable | 3sj4X-3v4bA:10.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a3s | 6-PHOSPHOFRUCTOKINASE (Bacillussubtilis) |
PF00365(PFK) | 5 | ILE A 286LEU A 267ILE A 130MET A 16GLY A 15 | None | 1.32A | 3sj4X-4a3sA:undetectable | 3sj4X-4a3sA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b4p | F18 FIMBRIAL ADHESINAC (Escherichiacoli) |
no annotation | 5 | ILE A 73LEU A 133ILE A 40LYS A 18GLY A 17 | None | 1.35A | 3sj4X-4b4pA:undetectable | 3sj4X-4b4pA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4edq | MALTOSE-BINDINGPERIPLASMICPROTEIN,MYOSIN-BINDING PROTEIN C,CARDIAC-TYPECHIMERIC PROTEIN (Escherichiacoli;Mus musculus) |
PF07679(I-set)PF13416(SBP_bac_8) | 5 | ILE A 133LEU A 199LYS A 257ILE A 227GLY A 192 | None | 1.17A | 3sj4X-4edqA:undetectable | 3sj4X-4edqA:9.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4exk | MALTOSE-BINDINGPERIPLASMIC PROTEIN,UNCHARACTERIZEDPROTEIN CHIMERA (Escherichiacoli;Salmonellaenterica) |
PF13416(SBP_bac_8)PF16583(ZirS_C) | 5 | ILE A 132LEU A 198LYS A 256ILE A 226GLY A 191 | None | 1.26A | 3sj4X-4exkA:undetectable | 3sj4X-4exkA:10.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g1j | SORTASE FAMILYPROTEIN (Streptococcusagalactiae) |
PF04203(Sortase) | 5 | ILE A 128LEU A 160ILE A 118PHE A 184GLY A 239 | None | 1.34A | 3sj4X-4g1jA:undetectable | 3sj4X-4g1jA:15.96 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4hc3 | PPCA (Geobactersulfurreducens) |
no annotation | 9 | ILE A 4LEU A 6LYS A 33LYS A 37ILE A 38PHE A 41MET A 45LYS A 49GLY A 50 | HEM A 72 (-4.4A)HEM A 74 ( 3.7A)DXC A 75 ( 4.4A)DXC A 75 ( 2.6A)DXC A 75 (-4.2A)DXC A 75 ( 4.3A)DXC A 75 (-4.2A)DXC A 75 ( 4.1A)DXC A 75 ( 3.7A) | 0.38A | 3sj4X-4hc3A:15.6 | 3sj4X-4hc3A:97.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hwv | PECTATE LYASE/AMBALLERGEN (Acidovoraxcitrulli) |
PF00544(Pec_lyase_C) | 5 | ILE A 417LEU A 385MET A 359LYS A 337GLY A 358 | None | 1.21A | 3sj4X-4hwvA:undetectable | 3sj4X-4hwvA:7.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i4i | 6-PHOSPHOFRUCTOKINASE (Geobacillusstearothermophilus) |
PF00365(PFK) | 5 | ILE A 286LEU A 267ILE A 130MET A 16GLY A 15 | None | 1.33A | 3sj4X-4i4iA:undetectable | 3sj4X-4i4iA:11.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ikm | MALTOSE-BINDINGPERIPLASMIC PROTEIN,CASPASE RECRUITMENTDOMAIN-CONTAININGPROTEIN 8 (Escherichiacoli;Homo sapiens) |
PF00619(CARD)PF13416(SBP_bac_8) | 5 | ILE A 133LEU A 199LYS A 257ILE A 227GLY A 192 | None | 1.28A | 3sj4X-4ikmA:undetectable | 3sj4X-4ikmA:12.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jx8 | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE[NADH] FABI (Escherichiacoli) |
PF13561(adh_short_C2) | 5 | ILE A 59LEU A 78LYS A 7PHE A 85GLY A 87 | None | 1.27A | 3sj4X-4jx8A:undetectable | 3sj4X-4jx8A:14.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kma | GM14141P (Drosophilamelanogaster) |
PF05076(SUFU)PF12470(SUFU_C) | 5 | ILE A 450LEU A 448PHE A 422MET A 419LYS A 363 | None | 1.29A | 3sj4X-4kmaA:undetectable | 3sj4X-4kmaA:8.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kv3 | CHIMERA FUSIONPROTEIN OF ESX-1SECRETION SYSTEMPROTEIN ECCD1 ANDMALTOSE-BINDINGPERIPLASMIC PROTEIN (Escherichiacoli;Mycobacteriumtuberculosis) |
PF08817(YukD)PF13416(SBP_bac_8) | 5 | ILE A 133LEU A 199LYS A 257ILE A 227GLY A 192 | None | 1.21A | 3sj4X-4kv3A:undetectable | 3sj4X-4kv3A:9.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m2g | L-ARGININEBETA-HYDROXYLASE (Streptomyceslavendulae) |
PF02668(TauD) | 5 | ILE A 168LEU A 114ILE A 74PHE A 63GLY A 70 | None | 1.43A | 3sj4X-4m2gA:undetectable | 3sj4X-4m2gA:10.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m2g | L-ARGININEBETA-HYDROXYLASE (Streptomyceslavendulae) |
PF02668(TauD) | 5 | ILE A 168LEU A 114LYS A 9PHE A 63GLY A 70 | None | 1.26A | 3sj4X-4m2gA:undetectable | 3sj4X-4m2gA:10.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n13 | PHOSPHATE ABCTRANSPORTER,PERIPLASMICPHOSPHATE-BINDINGPROTEIN (Borreliellaburgdorferi) |
PF12849(PBP_like_2) | 5 | ILE A 139LEU A 107LYS A 172PHE A 126GLY A 160 | NoneNoneNoneEDO A 305 ( 4.5A)EDO A 305 (-2.6A) | 1.30A | 3sj4X-4n13A:undetectable | 3sj4X-4n13A:13.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nes | UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE (Methanocaldococcusjannaschii) |
PF02350(Epimerase_2) | 5 | ILE A 225LEU A 285LYS A 329ILE A 331GLY A 324 | None | 1.37A | 3sj4X-4nesA:undetectable | 3sj4X-4nesA:11.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ozq | CHIMERA OFMALTOSE-BINDINGPERIPLASMIC PROTEINAND KINESIN FAMILYMEMBER 14 PROTEIN (Escherichiacoli;Mus musculus) |
PF00225(Kinesin)PF13416(SBP_bac_8) | 5 | ILE A-238LEU A-172LYS A-114ILE A-144GLY A-179 | None | 1.26A | 3sj4X-4ozqA:undetectable | 3sj4X-4ozqA:9.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p9n | CARBOXYLESTERASE (Sulfolobusshibatae) |
PF07859(Abhydrolase_3) | 5 | ILE A 174LEU A 74PHE A 301MET A 143GLY A 144 | None | 1.24A | 3sj4X-4p9nA:undetectable | 3sj4X-4p9nA:11.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4phx | PROTEIN AGGB (Escherichiacoli) |
no annotation | 5 | ILE B 3LEU B 5ILE B 92MET B 96LYS B 65 | None | 1.47A | 3sj4X-4phxB:undetectable | 3sj4X-4phxB:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4py9 | PUTATIVEEXOPOLYPHOSPHATASE-RELATED PROTEIN (Bacteroidesfragilis) |
PF01368(DHH) | 5 | ILE A 26LEU A 98ILE A 153MET A 174GLY A 173 | None | 1.27A | 3sj4X-4py9A:undetectable | 3sj4X-4py9A:12.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pzl | ADENYLATE KINASE (Francisellatularensis) |
PF00406(ADK)PF05191(ADK_lid) | 5 | ILE A 20LEU A 82LYS A 197ILE A 196GLY A 7 | NoneNoneFMT A 302 ( 4.6A)NoneNone | 0.97A | 3sj4X-4pzlA:undetectable | 3sj4X-4pzlA:14.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r0y | MALTOSE-BINDINGPERIPLASMIC PROTEIN,DISKSLARGE-ASSOCIATEDPROTEIN 1 (Escherichiacoli;Rattusnorvegicus) |
PF03359(GKAP)PF13416(SBP_bac_8) | 5 | ILE A 132LEU A 198LYS A 256ILE A 226GLY A 191 | None | 1.24A | 3sj4X-4r0yA:undetectable | 3sj4X-4r0yA:12.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tjv | VACUOLAR-SORTINGRECEPTOR 1 (Arabidopsisthaliana) |
PF02225(PA) | 5 | ILE A 151LEU A 28ILE A 115PHE A 90GLY A 58 | None | 1.35A | 3sj4X-4tjvA:undetectable | 3sj4X-4tjvA:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tsm | MALTOSE-BINDINGPROTEIN, PILINCHIMERA (Escherichiacoli;Clostridioidesdifficile) |
PF13416(SBP_bac_8) | 5 | ILE A 132LEU A 198LYS A 256ILE A 226GLY A 191 | None | 1.27A | 3sj4X-4tsmA:undetectable | 3sj4X-4tsmA:8.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4us4 | TRANSPORTER (Bacillushalodurans) |
PF00209(SNF) | 5 | ILE A 163LEU A 322ILE A 158PHE A 156GLY A 109 | None | 1.20A | 3sj4X-4us4A:undetectable | 3sj4X-4us4A:8.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wrn | MALTOSE-BINDINGPERIPLASMICPROTEIN,UROMODULIN (Escherichiacoli;Homo sapiens) |
PF00100(Zona_pellucida)PF13416(SBP_bac_8) | 5 | ILE A 156LEU A 222LYS A 280ILE A 250GLY A 215 | None | 1.09A | 3sj4X-4wrnA:undetectable | 3sj4X-4wrnA:7.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wvi | MALTOSE-BINDINGPERIPLASMICPROTEIN,SIGNALPEPTIDASE IB (Escherichiacoli;Staphylococcusaureus) |
PF00717(Peptidase_S24)PF13416(SBP_bac_8) | 5 | ILE A 138LEU A 204LYS A 262ILE A 232GLY A 197 | None | 1.23A | 3sj4X-4wviA:undetectable | 3sj4X-4wviA:8.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xa2 | MALTOSE-BINDINGPERIPLASMICPROTEIN,MBP-PILA: C (Acinetobacterbaumannii;Escherichiacoli) |
PF00114(Pilin)PF13416(SBP_bac_8) | 5 | ILE A 132LEU A 198LYS A 256ILE A 226GLY A 191 | None | 1.19A | 3sj4X-4xa2A:undetectable | 3sj4X-4xa2A:9.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xd0 | TDP-3-AMINOQUINOVOSE-N-FORMYLTRANSFERASE (Providenciaalcalifaciens) |
PF00551(Formyl_trans_N)PF12796(Ank_2) | 5 | ILE A 90ILE A 79PHE A 76LYS A 8GLY A 7 | NoneFON A 402 (-4.0A)NoneT3F A 403 (-3.2A)None | 1.30A | 3sj4X-4xd0A:undetectable | 3sj4X-4xd0A:9.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zoh | PUTATIVEOXIDOREDUCTASEIRON-SULFUR SUBUNIT (Sulfurisphaeratokodaii) |
PF00111(Fer2)PF01799(Fer2_2) | 5 | ILE C 94LEU C 121LYS C 65ILE C 58GLY C 135 | NoneNoneFES C 201 ( 4.5A)NoneNone | 1.15A | 3sj4X-4zohC:undetectable | 3sj4X-4zohC:17.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ah1 | TRIACYLGLYCEROLLIPASE (Clostridiumbotulinum) |
no annotation | 5 | ILE A 288LEU A 269ILE A 266PHE A 89GLY A 88 | None | 1.14A | 3sj4X-5ah1A:undetectable | 3sj4X-5ah1A:9.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bpt | MGC81278 PROTEIN (Xenopus laevis) |
PF12894(ANAPC4_WD40)PF12896(ANAPC4) | 6 | ILE A 103LEU A 99ILE A 84PHE A 97MET A 185GLY A 184 | None | 1.25A | 3sj4X-5bptA:undetectable | 3sj4X-5bptA:6.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cfv | MALTOSE-BINDINGPERIPLASMICPROTEIN,MALTOSE-BINDING PERIPLASMICPROTEIN,PILA FUSIONPROTEIN (Escherichiacoli;Acinetobacternosocomialis) |
PF00114(Pilin)PF01547(SBP_bac_1) | 5 | ILE A 132LEU A 198LYS A 256ILE A 226GLY A 191 | None | 1.25A | 3sj4X-5cfvA:undetectable | 3sj4X-5cfvA:8.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gp4 | GLUTAMATEDECARBOXYLASE (Lactobacillusbrevis) |
no annotation | 5 | ILE C 438LEU C 441ILE C 378PHE C 366GLY C 365 | None | 1.25A | 3sj4X-5gp4C:undetectable | 3sj4X-5gp4C:10.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h7n | NLRP12-PYD WITH MBPTAG (Homo sapiens) |
PF02758(PYRIN)PF13416(SBP_bac_8) | 5 | ILE A 133LEU A 199LYS A 257ILE A 227GLY A 192 | None | 1.22A | 3sj4X-5h7nA:undetectable | 3sj4X-5h7nA:8.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kym | 1-ACYL-SN-GLYCEROL-3-PHOSPHATEACYLTRANSFERASE (Thermotogamaritima) |
PF01553(Acyltransferase) | 5 | ILE A 49LEU A 121ILE A 93PHE A 102LYS A 105 | None | 1.49A | 3sj4X-5kymA:undetectable | 3sj4X-5kymA:15.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ltq | GREEN FLUORESCENTPROTEIN BLFP-Y3 (Branchiostomalanceolatum) |
PF01353(GFP) | 5 | ILE A 57LEU A 53LYS A 43PHE A 20GLY A 13 | CR2 A 59 ( 4.2A)NoneNoneNoneNone | 1.39A | 3sj4X-5ltqA:undetectable | 3sj4X-5ltqA:12.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mz9 | - (-) |
no annotation | 5 | LEU A 345LYS A 301ILE A 395PHE A 397GLY A 399 | None | 1.43A | 3sj4X-5mz9A:undetectable | 3sj4X-5mz9A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ue7 | PHOSPHOMANNOMUTASE (Candidaalbicans) |
PF03332(PMM) | 5 | ILE A 28LEU A 60ILE A 45PHE A 47GLY A 49 | None | 1.40A | 3sj4X-5ue7A:undetectable | 3sj4X-5ue7A:13.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xcb | PROBABLE SURFACEPROTEIN (Clostridiumperfringens) |
no annotation | 5 | ILE A 154LYS A 109ILE A 111PHE A 78GLY A 85 | None | 1.43A | 3sj4X-5xcbA:undetectable | 3sj4X-5xcbA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xsy | SODIUM CHANNELPROTEIN (Electrophoruselectricus) |
PF00520(Ion_trans)PF06512(Na_trans_assoc) | 5 | LEU A1510ILE A1496PHE A1488MET A1470GLY A1469 | None | 1.42A | 3sj4X-5xsyA:undetectable | 3sj4X-5xsyA:3.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6anv | ANTI-CRISPR PROTEINACRF1 FUSED WITHC-TERMINAL MBP TAG (Escherichiacoli;Pseudomonasphage JBD30) |
no annotation | 5 | ILE A 212LEU A 278LYS A 336ILE A 306GLY A 271 | None | 1.26A | 3sj4X-6anvA:undetectable | 3sj4X-6anvA:10.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bze | B-CELLLYMPHOMA/LEUKEMIA 10 (Homo sapiens) |
no annotation | 5 | ILE A 32LEU A 69LYS A 45LYS A 77GLY A 78 | None | 1.41A | 3sj4X-6bzeA:undetectable | 3sj4X-6bzeA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f9w | PROTEIN LSM14HOMOLOG A (Homo sapiens) |
no annotation | 5 | ILE A 12LEU A 38LYS A 17ILE A 15GLY A 69 | None | 1.37A | 3sj4X-6f9wA:undetectable | 3sj4X-6f9wA:undetectable |