SIMILAR PATTERNS OF AMINO ACIDS FOR 3SJ0_X_DXCX75

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1afp ANTIFUNGAL PROTEIN
FROM ASPERGILLUS
GIGANTEUS

(Aspergillus
giganteus) 		PF11402
(Antifungal_prot) 		4 ILE A  25
PHE A  42
LYS A  46
GLY A  47
 None
 1.02A 3sj0X-1afpA:
undetectable		 3sj0X-1afpA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c3e GLYCINAMIDE
RIBONUCLEOTIDE
TRANSFORMYLASE

(Escherichia
coli) 		PF00551
(Formyl_trans_N) 		4 ILE A 181
PHE A 138
MET A 191
GLY A 102
 None
 1.22A 3sj0X-1c3eA:
undetectable		 3sj0X-1c3eA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6v METHYL-COENZYME M
REDUCTASE I BETA
SUBUNIT

(Methanopyrus
kandleri) 		PF02241
(MCR_beta)
PF02783
(MCR_beta_N) 		4 ILE B  79
LYS B 158
MET B 137
GLY B 136
 None
 1.21A 3sj0X-1e6vB:
undetectable		 3sj0X-1e6vB:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1flc HAEMAGGLUTININ-ESTER
ASE-FUSION
GLYCOPROTEIN
HAEMAGGLUTININ-ESTER
ASE-FUSION
GLYCOPROTEIN

(Influenza C
virus;
Influenza C
virus) 		PF02710
(Hema_HEFG)
PF03996
(Hema_esterase)
PF08720
(Hema_stalk) 		4 ILE B  77
PHE A 396
LYS A 108
GLY A 309
 None
 1.22A 3sj0X-1flcB:
undetectable		 3sj0X-1flcB:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jmz AMINE DEHYDROGENASE

(Pseudomonas
putida) 		no annotation 4 ILE B  99
LYS B  76
PHE B  79
GLY B 135
 None
 1.19A 3sj0X-1jmzB:
undetectable		 3sj0X-1jmzB:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kbv MAJOR OUTER MEMBRANE
PROTEIN PAN 1

(Neisseria
gonorrhoeae) 		PF00394
(Cu-oxidase)
PF07732
(Cu-oxidase_3) 		4 ILE A 144
LYS A  48
PHE A 174
GLY A 205
 None
 1.24A 3sj0X-1kbvA:
undetectable		 3sj0X-1kbvA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kig FACTOR XA

(Bos taurus) 		PF00089
(Trypsin) 		4 ILE H 176
PHE H 225
LYS H 223
GLY H 223
 None
 1.21A 3sj0X-1kigH:
undetectable		 3sj0X-1kigH:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l8t AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E

(Enterococcus
faecalis) 		PF01636
(APH) 		4 ILE A 125
LYS A  75
PHE A 206
GLY A 205
 None
 1.22A 3sj0X-1l8tA:
undetectable		 3sj0X-1l8tA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q1r PUTIDAREDOXIN
REDUCTASE

(Pseudomonas
putida) 		PF07992
(Pyr_redox_2)
PF14759
(Reductase_C) 		4 ILE A 243
LYS A 170
LYS A  56
GLY A  55
 None
 1.19A 3sj0X-1q1rA:
undetectable		 3sj0X-1q1rA:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qu4 ORNITHINE
DECARBOXYLASE

(Trypanosoma
brucei) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 ILE A 212
PHE A 219
MET A 229
GLY A 193
 None
 1.06A 3sj0X-1qu4A:
undetectable		 3sj0X-1qu4A:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tbu PEROXISOMAL
ACYL-COENZYME A
THIOESTER HYDROLASE
1

(Saccharomyces
cerevisiae) 		PF13622
(4HBT_3) 		4 ILE A 112
PHE A 108
LYS A  40
GLY A  42
 None
 1.18A 3sj0X-1tbuA:
undetectable		 3sj0X-1tbuA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y9a NADP-DEPENDENT
ALCOHOL
DEHYDROGENASE

(Entamoeba
histolytica) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 ILE A 351
LYS A  17
PHE A 124
GLY A 118
 None
 1.24A 3sj0X-1y9aA:
undetectable		 3sj0X-1y9aA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yiq QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida) 		PF01011
(PQQ)
PF13360
(PQQ_2)
PF13442
(Cytochrome_CBB3) 		4 ILE A 277
PHE A 273
MET A 215
GLY A 214
 None
 1.23A 3sj0X-1yiqA:
undetectable		 3sj0X-1yiqA:
7.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2azn PUTATIVE
5-AMINO-6-(5-PHOSPHO
RIBOSYLAMINO)URACIL
REDUCTASE

(Methanocaldococcus
jannaschii) 		PF01872
(RibD_C) 		4 ILE A  79
LYS A 133
LYS A 165
GLY A 162
 None
None
None
NAP  A2001 ( 3.7A)
 1.12A 3sj0X-2aznA:
undetectable		 3sj0X-2aznA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2csu 457AA LONG
HYPOTHETICAL PROTEIN

(Pyrococcus
horikoshii) 		PF13380
(CoA_binding_2)
PF13607
(Succ_CoA_lig) 		4 ILE A  14
LYS A  90
LYS A   9
GLY A  10
 None
 1.08A 3sj0X-2csuA:
undetectable		 3sj0X-2csuA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dfs MYOSIN-5A

(Gallus gallus) 		PF00063
(Myosin_head)
PF00612
(IQ) 		4 ILE A 487
LYS A 739
PHE A 750
GLY A 745
 None
 1.16A 3sj0X-2dfsA:
undetectable		 3sj0X-2dfsA:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fgc ACETOLACTATE
SYNTHASE, SMALL
SUBUNIT

(Thermotoga
maritima) 		PF01842
(ACT)
PF10369
(ALS_ss_C) 		4 ILE A 174
LYS A 158
PHE A 162
GLY A 138
 None
 0.75A 3sj0X-2fgcA:
undetectable		 3sj0X-2fgcA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g5t DIPEPTIDYL PEPTIDASE
4

(Homo sapiens) 		PF00326
(Peptidase_S9)
PF00930
(DPPIV_N) 		4 ILE A 518
MET A 425
LYS A 423
GLY A 424
 None
 1.21A 3sj0X-2g5tA:
undetectable		 3sj0X-2g5tA:
7.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gvh AGR_L_2016P

(Agrobacterium
fabrum) 		PF03061
(4HBT) 		4 ILE A  22
PHE A  81
MET A  43
GLY A  39
 None
 1.12A 3sj0X-2gvhA:
undetectable		 3sj0X-2gvhA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gvh AGR_L_2016P

(Agrobacterium
fabrum) 		PF03061
(4HBT) 		4 ILE A  78
PHE A  81
MET A  43
GLY A  39
 None
 1.21A 3sj0X-2gvhA:
undetectable		 3sj0X-2gvhA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hcz BETA-EXPANSIN 1A

(Zea mays) 		PF01357
(Pollen_allerg_1)
PF03330
(DPBB_1) 		4 ILE X 152
LYS X 225
PHE X 210
GLY X 208
 None
 1.05A 3sj0X-2hczX:
undetectable		 3sj0X-2hczX:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i5h HYPOTHETICAL PROTEIN
AF1531

(Archaeoglobus
fulgidus) 		PF04919
(DUF655) 		4 ILE A 175
MET A 143
LYS A 140
GLY A 139
 None
 1.23A 3sj0X-2i5hA:
undetectable		 3sj0X-2i5hA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ib5 CHROMO PROTEIN

(Epiactis
japonica) 		PF01353
(GFP) 		4 ILE A  57
LYS A  44
PHE A 211
GLY A 208
 None
 1.18A 3sj0X-2ib5A:
undetectable		 3sj0X-2ib5A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iuk SEED LIPOXYGENASE

(Glycine max) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		4 ILE A 149
PHE A 117
LYS A  86
GLY A  85
 None
 1.22A 3sj0X-2iukA:
undetectable		 3sj0X-2iukA:
5.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nrj HBL B PROTEIN

(Bacillus cereus) 		PF05791
(Bacillus_HBL) 		4 ILE A 125
LYS A 307
PHE A 306
GLY A 116
 None
 0.83A 3sj0X-2nrjA:
undetectable		 3sj0X-2nrjA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p2m ACETYL-COENZYME A
SYNTHETASE

(Salmonella
enterica) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
PF16177
(ACAS_N) 		4 ILE A  45
LYS A  56
PHE A  38
GLY A 443
 None
 1.22A 3sj0X-2p2mA:
undetectable		 3sj0X-2p2mA:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qgh DIAMINOPIMELATE
DECARBOXYLASE

(Helicobacter
pylori) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 ILE A 350
PHE A 335
MET A 293
GLY A 292
 None
 1.18A 3sj0X-2qghA:
undetectable		 3sj0X-2qghA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wk2 CHITINASE A

(Serratia
marcescens) 		PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N) 		4 ILE A 192
PHE A 306
MET A 257
GLY A 254
 None
 1.11A 3sj0X-2wk2A:
undetectable		 3sj0X-2wk2A:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2woz KELCH REPEAT AND BTB
DOMAIN-CONTAINING
PROTEIN 10

(Rattus
norvegicus) 		PF01344
(Kelch_1) 		4 ILE A 443
PHE A 488
LYS A 455
GLY A 454
 None
 1.10A 3sj0X-2wozA:
undetectable		 3sj0X-2wozA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xci 3-DEOXY-D-MANNO-2-OC
TULOSONIC ACID
TRANSFERASE

(Aquifex
aeolicus) 		PF04413
(Glycos_transf_N) 		4 ILE A 171
LYS A 258
PHE A 177
GLY A 175
 None
 1.10A 3sj0X-2xciA:
undetectable		 3sj0X-2xciA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo sapiens) 		PF00079
(Serpin) 		4 ILE A 116
LYS A 125
PHE A 126
GLY A  63
 None
 1.12A 3sj0X-2xn6A:
undetectable		 3sj0X-2xn6A:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yfq NAD-SPECIFIC
GLUTAMATE
DEHYDROGENASE

(Peptoniphilus
asaccharolyticus) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		4 ILE A  43
LYS A 106
PHE A 157
MET A 154
 None
 1.18A 3sj0X-2yfqA:
undetectable		 3sj0X-2yfqA:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2znm THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBA

(Neisseria
meningitidis) 		PF13462
(Thioredoxin_4) 		4 ILE A 155
LYS A   3
PHE A 164
GLY A 171
 None
 1.23A 3sj0X-2znmA:
undetectable		 3sj0X-2znmA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a0j COLD SHOCK PROTEIN

(Thermus
thermophilus) 		PF00313
(CSD) 		4 LYS A  58
PHE A   9
LYS A  13
GLY A  14
 None
 1.18A 3sj0X-3a0jA:
undetectable		 3sj0X-3a0jA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b43 TITIN

(Oryctolagus
cuniculus) 		PF07679
(I-set) 		4 ILE A 234
LYS A 214
PHE A 213
GLY A 211
 None
 1.14A 3sj0X-3b43A:
undetectable		 3sj0X-3b43A:
8.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c5m OLIGOGALACTURONATE
LYASE

(Vibrio
parahaemolyticus) 		PF14583
(Pectate_lyase22) 		4 ILE A 377
LYS A  41
PHE A  43
GLY A  47
 None
 1.13A 3sj0X-3c5mA:
undetectable		 3sj0X-3c5mA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cg3 UPF0100 PROTEIN
PH0151

(Pyrococcus
horikoshii) 		PF13531
(SBP_bac_11) 		4 ILE A  32
LYS A  48
LYS A 309
GLY A 307
 None
 1.25A 3sj0X-3cg3A:
undetectable		 3sj0X-3cg3A:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3czm L-LACTATE
DEHYDROGENASE

(Toxoplasma
gondii) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 ILE A 255
PHE A 134
MET A 159
GLY A 297
 None
 1.04A 3sj0X-3czmA:
undetectable		 3sj0X-3czmA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3din PREPROTEIN
TRANSLOCASE SUBUNIT
SECY
PREPROTEIN
TRANSLOCASE SUBUNIT
SECG

(Thermotoga
maritima;
Thermotoga sp.
RQ2) 		PF00344
(SecY)
PF03840
(SecG) 		4 ILE C 187
LYS E  26
PHE C 170
GLY C 167
 None
 1.22A 3sj0X-3dinC:
undetectable		 3sj0X-3dinC:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e8v POSSIBLE
TRANSGLUTAMINASE-FAM
ILY PROTEIN

(Bacteroides
fragilis) 		no annotation 4 ILE A 366
PHE A 310
LYS A 289
GLY A 291
 None
 1.17A 3sj0X-3e8vA:
undetectable		 3sj0X-3e8vA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g5a FMN
ADENYLYLTRANSFERASE

([Candida]
glabrata) 		PF01507
(PAPS_reduct) 		4 ILE A 277
LYS A  65
PHE A 114
GLY A 224
 None
APC  A 305 (-2.9A)
None
None
 0.99A 3sj0X-3g5aA:
undetectable		 3sj0X-3g5aA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g5j PUTATIVE ATP/GTP
BINDING PROTEIN

(Clostridioides
difficile) 		PF00581
(Rhodanese) 		4 ILE A  75
PHE A  40
LYS A  63
GLY A  64
 None
None
None
PGE  A 302 ( 4.0A)
 1.13A 3sj0X-3g5jA:
undetectable		 3sj0X-3g5jA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ho6 TOXIN A

(Clostridioides
difficile) 		PF11713
(Peptidase_C80) 		4 ILE A 197
PHE A 123
LYS A 115
GLY A 114
 None
 1.18A 3sj0X-3ho6A:
undetectable		 3sj0X-3ho6A:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jq0 SUSD SUPERFAMILY
PROTEIN

(Bacteroides
vulgatus) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 ILE A 465
PHE A 245
LYS A 220
GLY A 221
 None
 1.13A 3sj0X-3jq0A:
undetectable		 3sj0X-3jq0A:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3js6 UNCHARACTERIZED PARM
PROTEIN

(Staphylococcus
aureus) 		no annotation 4 ILE A 100
PHE A 133
MET A 120
GLY A 119
 None
 1.14A 3sj0X-3js6A:
undetectable		 3sj0X-3js6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lij CALCIUM/CALMODULIN
DEPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum) 		PF00069
(Pkinase)
PF13499
(EF-hand_7) 		4 ILE A 295
PHE A 260
LYS A 274
GLY A 275
 None
 0.98A 3sj0X-3lijA:
undetectable		 3sj0X-3lijA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lms CARBOXYPEPTIDASE B2

(Homo sapiens) 		PF00246
(Peptidase_M14) 		4 ILE A  62
MET A  32
LYS A  55
GLY A  54
 None
 1.24A 3sj0X-3lmsA:
undetectable		 3sj0X-3lmsA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nie MAP2 KINASE

(Plasmodium
falciparum) 		PF00069
(Pkinase) 		4 ILE A 240
LYS A 134
PHE A 247
GLY A 343
 None
 1.23A 3sj0X-3nieA:
undetectable		 3sj0X-3nieA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN

(Homo sapiens) 		PF00057
(Ldl_recept_a)
PF00090
(TSP_1)
PF01823
(MACPF) 		4 ILE A 337
PHE A 372
LYS A 376
GLY A 375
 None
 1.24A 3sj0X-3ojyA:
undetectable		 3sj0X-3ojyA:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3on3 KETO/OXOACID
FERREDOXIN
OXIDOREDUCTASE,
GAMMA SUBUNIT

(Geobacter
sulfurreducens) 		PF01558
(POR) 		4 ILE A  23
MET A 172
LYS A 176
GLY A 173
 None
 1.20A 3sj0X-3on3A:
undetectable		 3sj0X-3on3A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3psh PROTEIN HI_1472

(Haemophilus
influenzae) 		PF01497
(Peripla_BP_2) 		4 ILE A  35
LYS A 174
PHE A 172
LYS A  60
 None
 0.98A 3sj0X-3pshA:
undetectable		 3sj0X-3pshA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tlz MCCF

(Escherichia
coli) 		PF02016
(Peptidase_S66) 		4 ILE A 272
LYS A 331
PHE A 328
GLY A 206
 None
 1.23A 3sj0X-3tlzA:
undetectable		 3sj0X-3tlzA:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vut DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 4

(Homo sapiens) 		PF00069
(Pkinase) 		4 ILE A 341
PHE A 366
LYS A 207
GLY A 206
 None
 1.05A 3sj0X-3vutA:
undetectable		 3sj0X-3vutA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zbm COPPER-CONTAINING
NITRITE REDUCTASE

(Ralstonia
pickettii) 		PF07732
(Cu-oxidase_3)
PF13442
(Cytochrome_CBB3) 		4 ILE A 144
LYS A  48
PHE A 174
GLY A 205
 None
 1.14A 3sj0X-3zbmA:
undetectable		 3sj0X-3zbmA:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aw2 SERINE/THREONINE-PRO
TEIN KINASE MRCK
ALPHA

(Rattus
norvegicus) 		PF00069
(Pkinase)
PF00433
(Pkinase_C) 		4 ILE A 187
LYS A 339
PHE A 337
GLY A 330
 None
 1.04A 3sj0X-4aw2A:
undetectable		 3sj0X-4aw2A:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bma UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE

(Aspergillus
fumigatus) 		PF01704
(UDPGP) 		4 ILE A 252
LYS A 364
PHE A 365
LYS A 421
 None
 1.24A 3sj0X-4bmaA:
undetectable		 3sj0X-4bmaA:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dkm AMPHIOXUS GREEN
FLUORESCENT PROTEIN,
GFPC1A

(Branchiostoma
floridae) 		PF01353
(GFP) 		4 ILE A  57
LYS A  43
PHE A  20
GLY A  13
 CR2  A  60 ( 3.6A)
None
None
None
 1.00A 3sj0X-4dkmA:
undetectable		 3sj0X-4dkmA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dkn AMPHIOXUS GREEN
FLUORESCENT PROTEIN,
GFPA1

(Branchiostoma
floridae) 		PF01353
(GFP) 		4 ILE A   9
LYS A  43
PHE A  20
GLY A  13
 None
 1.25A 3sj0X-4dknA:
undetectable		 3sj0X-4dknA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e8d GLYCOSYL HYDROLASE,
FAMILY 35

(Streptococcus
pneumoniae) 		PF01301
(Glyco_hydro_35) 		4 ILE A 579
LYS A 588
PHE A 543
GLY A 529
 None
 1.06A 3sj0X-4e8dA:
undetectable		 3sj0X-4e8dA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4frx ANAEROBICALLY-INDUCE
D OUTER MEMBRANE
PORIN OPRE

(Pseudomonas
aeruginosa) 		PF03573
(OprD) 		4 ILE A  18
LYS A 161
PHE A  85
GLY A  63
 None
 1.07A 3sj0X-4frxA:
undetectable		 3sj0X-4frxA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gl8 OLIGOPEPTIDE ABC
TRANSPORTER OPPAIV

(Borreliella
burgdorferi) 		PF00496
(SBP_bac_5) 		4 ILE A 526
LYS A 265
PHE A 242
GLY A  56
 None
 0.96A 3sj0X-4gl8A:
undetectable		 3sj0X-4gl8A:
8.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hc3 PPCA

(Geobacter
sulfurreducens) 		no annotation 7 ILE A   4
LYS A  33
LYS A  37
PHE A  41
MET A  45
LYS A  49
GLY A  50
 HEM  A  72 (-4.4A)
DXC  A  75 ( 4.4A)
DXC  A  75 ( 2.6A)
DXC  A  75 ( 4.3A)
DXC  A  75 (-4.2A)
DXC  A  75 ( 4.1A)
DXC  A  75 ( 3.7A)
 0.15A 3sj0X-4hc3A:
15.7		 3sj0X-4hc3A:
97.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hln STARCH SYNTHASE I

(Hordeum vulgare) 		PF00534
(Glycos_transf_1)
PF08323
(Glyco_transf_5) 		4 ILE A 422
LYS A 473
PHE A 476
GLY A 478
 None
 1.16A 3sj0X-4hlnA:
undetectable		 3sj0X-4hlnA:
7.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hlu ENERGY-COUPLING
FACTOR TRANSPORTER
ATP-BINDING PROTEIN
ECFA

(Thermotoga
maritima) 		no annotation 4 ILE D1058
PHE D1152
LYS D 999
GLY D1001
 None
 0.98A 3sj0X-4hluD:
undetectable		 3sj0X-4hluD:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hvf GREEN FLUORESCENT
PROTEIN BLFP-Y6

(Branchiostoma
lanceolatum) 		PF01353
(GFP) 		4 ILE A  57
LYS A  43
PHE A  20
GLY A  13
 CR2  A  58 ( 4.0A)
None
None
None
 1.19A 3sj0X-4hvfA:
undetectable		 3sj0X-4hvfA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hwv PECTATE LYASE/AMB
ALLERGEN

(Acidovorax
citrulli) 		PF00544
(Pec_lyase_C) 		4 ILE A 417
MET A 359
LYS A 337
GLY A 358
 None
 1.22A 3sj0X-4hwvA:
undetectable		 3sj0X-4hwvA:
7.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ikh GLUTATHIONE
S-TRANSFERASE

(Pseudomonas
protegens) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 ILE A 126
LYS A 212
PHE A 208
GLY A 204
 None
 1.07A 3sj0X-4ikhA:
undetectable		 3sj0X-4ikhA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k59 RNA BINDING PROTEIN
RSMF

(Pseudomonas
aeruginosa) 		PF02599
(CsrA) 		4 ILE A  41
LYS A  22
MET A   4
GLY A   5
 None
 1.17A 3sj0X-4k59A:
undetectable		 3sj0X-4k59A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ld7 DIMETHYLALLYL
TRYPTOPHAN SYNTHASE

(Aspergillus
fischeri) 		PF11991
(Trp_DMAT) 		4 ILE A 266
PHE A 103
MET A 110
GLY A 126
 None
 1.24A 3sj0X-4ld7A:
undetectable		 3sj0X-4ld7A:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4luj OROTIDINE
5'-PHOSPHATE
DECARBOXYLASE

(Methanocaldococcus
jannaschii) 		PF00215
(OMPdecase) 		4 ILE A 209
LYS A  69
LYS A 126
GLY A 102
 BMP  A 301 ( 4.4A)
None
None
None
 1.16A 3sj0X-4lujA:
undetectable		 3sj0X-4lujA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m2g L-ARGININE
BETA-HYDROXYLASE

(Streptomyces
lavendulae) 		PF02668
(TauD) 		4 ILE A 168
LYS A   9
PHE A  63
GLY A  70
 None
 1.17A 3sj0X-4m2gA:
undetectable		 3sj0X-4m2gA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n1u 7,8-DIHYDRO-8-OXOGUA
NINE TRIPHOSPHATASE

(Homo sapiens) 		PF00293
(NUDIX) 		4 ILE A  91
PHE A  35
MET A 101
GLY A  21
 None
None
SO4  A 202 (-3.5A)
None
 1.24A 3sj0X-4n1uA:
undetectable		 3sj0X-4n1uA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qmk TYPE III SECRETION
SYSTEM EFFECTOR
PROTEIN EXOU

(Pseudomonas
fluorescens) 		PF01734
(Patatin) 		4 ILE A 264
PHE A 239
LYS A 142
GLY A 141
 None
 1.20A 3sj0X-4qmkA:
undetectable		 3sj0X-4qmkA:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r16 418AA LONG
HYPOTHETICAL
UDP-N-ACETYL-D-MANNO
SAMINURONIC ACID
DEHYDROGENASE

(Pyrococcus
horikoshii) 		PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N) 		4 ILE A 370
PHE A 408
LYS A 387
GLY A 386
 None
 0.98A 3sj0X-4r16A:
undetectable		 3sj0X-4r16A:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yo1 DEGQ

(Legionella
pneumophila) 		PF13180
(PDZ_2)
PF13365
(Trypsin_2) 		4 ILE A 204
LYS A 132
LYS A 198
GLY A 199
 None
CD  A 401 (-3.4A)
None
None
 1.21A 3sj0X-4yo1A:
undetectable		 3sj0X-4yo1A:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ysj CALMODULIN-LIKE
DOMAIN PROTEIN
KINASE

(Eimeria tenella) 		PF00069
(Pkinase)
PF13499
(EF-hand_7) 		4 ILE A 262
PHE A 227
LYS A 241
GLY A 242
 None
 1.23A 3sj0X-4ysjA:
undetectable		 3sj0X-4ysjA:
6.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bpt MGC81278 PROTEIN

(Xenopus laevis) 		PF12894
(ANAPC4_WD40)
PF12896
(ANAPC4) 		4 ILE A 103
PHE A  97
MET A 185
GLY A 184
 None
 1.24A 3sj0X-5bptA:
undetectable		 3sj0X-5bptA:
7.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cov NAEGLERIA GRUBERI
RNA LIGASE

(Naegleria
gruberi) 		PF09414
(RNA_ligase) 		4 ILE A  56
PHE A 101
MET A  98
GLY A  47
 None
 1.15A 3sj0X-5covA:
undetectable		 3sj0X-5covA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d9a RNA-DIRECTED RNA
POLYMERASE CATALYTIC
SUBUNIT

(Influenza C
virus) 		PF00602
(Flu_PB1) 		4 ILE B  18
LYS B 482
LYS B 237
GLY B 236
 None
 1.19A 3sj0X-5d9aB:
undetectable		 3sj0X-5d9aB:
6.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5df0 AC-CHIA

(Autographa
californica
multiple
nucleopolyhedrovirus) 		PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N) 		4 ILE A 182
PHE A 296
MET A 247
GLY A 244
 None
 1.10A 3sj0X-5df0A:
undetectable		 3sj0X-5df0A:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ed4 RESPONSE REGULATOR

(Mycobacterium
tuberculosis) 		PF00072
(Response_reg)
PF00486
(Trans_reg_C) 		4 ILE A 135
LYS A 121
PHE A  97
GLY A  79
 None
CA  A 301 ( 3.8A)
None
None
 1.14A 3sj0X-5ed4A:
undetectable		 3sj0X-5ed4A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA

(Homo sapiens;
Escherichia
virus T4) 		PF00454
(PI3_PI4_kinase)
PF00959
(Phage_lysozyme) 		4 ILE A 420
LYS A 407
PHE A 351
GLY A 195
 None
 1.13A 3sj0X-5eutA:
undetectable		 3sj0X-5eutA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f7r LMO0178 PROTEIN

(Listeria
monocytogenes) 		no annotation 4 ILE E 227
LYS E 332
PHE E 212
GLY E 206
 None
 1.14A 3sj0X-5f7rE:
undetectable		 3sj0X-5f7rE:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fwj HISTONE DEMETHYLASE
JARID1C

(Homo sapiens) 		PF02373
(JmjC)
PF02375
(JmjN)
PF02928
(zf-C5HC2) 		4 ILE A  69
LYS A 405
PHE A 397
GLY A 505
 None
 1.19A 3sj0X-5fwjA:
undetectable		 3sj0X-5fwjA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo sapiens) 		PF03071
(GNT-I)
PF15711
(ILEI) 		4 ILE A 134
PHE A 163
MET A 166
GLY A 274
 None
 1.24A 3sj0X-5gggA:
undetectable		 3sj0X-5gggA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gpr CHITINASE

(Ostrinia
furnacalis) 		PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N) 		4 ILE A 185
PHE A 299
MET A 250
GLY A 247
 ILE  A 185 ( 0.7A)
PHE  A 299 ( 1.3A)
MET  A 250 ( 0.0A)
GLY  A 247 ( 0.0A)
 1.13A 3sj0X-5gprA:
undetectable		 3sj0X-5gprA:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gt5 PECTATE LYASE

(Paenibacillus
sp. 0602) 		no annotation 4 ILE A 126
LYS A 438
MET A  55
LYS A  32
 None
 1.14A 3sj0X-5gt5A:
undetectable		 3sj0X-5gt5A:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jbo BETA-GLUCOSIDASE

(Trichoderma
harzianum) 		PF00232
(Glyco_hydro_1) 		4 ILE A 382
LYS A 378
PHE A 310
GLY A 237
 None
 1.20A 3sj0X-5jboA:
undetectable		 3sj0X-5jboA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kja APOCAROTENOID-15,15'
-OXYGENASE

(Synechocystis
sp. PCC 6803) 		PF03055
(RPE65) 		4 ILE A 133
LYS A  66
PHE A 113
GLY A 269
 None
 1.08A 3sj0X-5kjaA:
undetectable		 3sj0X-5kjaA:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5llq METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE

(Sulfolobus
solfataricus) 		PF01035
(DNA_binding_1) 		4 ILE A 117
LYS A  67
LYS A  21
GLY A  22
 None
 1.15A 3sj0X-5llqA:
undetectable		 3sj0X-5llqA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5my0 FATTY ACID SYNTHASE

(Mus musculus) 		no annotation 4 ILE B 761
PHE B 516
MET B 511
GLY B 507
 None
 1.23A 3sj0X-5my0B:
undetectable		 3sj0X-5my0B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n4c PROLYL
OLIGOPEPTIDASE

(Galerina
marginata) 		no annotation 4 ILE A 587
LYS A 546
PHE A 553
GLY A 495
 None
 1.14A 3sj0X-5n4cA:
undetectable		 3sj0X-5n4cA:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n6y NITROGENASE
VANADIUM-IRON
PROTEIN BETA CHAIN

(Azotobacter
vinelandii) 		no annotation 4 ILE E 331
LYS E 439
PHE E 344
GLY E 451
 None
 1.08A 3sj0X-5n6yE:
undetectable		 3sj0X-5n6yE:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v5f AT3G11770

(Arabidopsis
thaliana) 		PF01612
(DNA_pol_A_exo1) 		4 ILE A 124
LYS A  72
PHE A  51
GLY A 108
 None
 1.25A 3sj0X-5v5fA:
undetectable		 3sj0X-5v5fA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vfr 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT
11

(Homo sapiens) 		no annotation 4 ILE X 336
LYS X 372
PHE X 374
GLY X 376
 None
 1.22A 3sj0X-5vfrX:
undetectable		 3sj0X-5vfrX:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xcb PROBABLE SURFACE
PROTEIN

(Clostridium
perfringens) 		no annotation 4 ILE A 154
LYS A 109
PHE A  78
GLY A  85
 None
 1.18A 3sj0X-5xcbA:
undetectable		 3sj0X-5xcbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zl9 CHITINASE AB

(Serratia
marcescens) 		no annotation 4 ILE A 192
PHE A 306
MET A 257
GLY A 254
 None
 1.09A 3sj0X-5zl9A:
undetectable		 3sj0X-5zl9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bf6 INSULIN-DEGRADING
ENZYME

(Homo sapiens) 		no annotation 4 ILE A 338
LYS A 521
LYS A 523
GLY A 342
 None
 1.23A 3sj0X-6bf6A:
undetectable		 3sj0X-6bf6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6brk DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1

(Mus musculus) 		no annotation 4 ILE A 223
PHE A 299
LYS A 320
GLY A 321
 None
 1.24A 3sj0X-6brkA:
undetectable		 3sj0X-6brkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cj7 SERPIN-12

(Manduca sexta) 		no annotation 4 ILE A  72
LYS A 137
PHE A 161
GLY A 163
 None
 1.01A 3sj0X-6cj7A:
undetectable		 3sj0X-6cj7A:
undetectable