SIMILAR PATTERNS OF AMINO ACIDS FOR 3SFU_B_RBVB601_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bdg | HEXOKINASE (Schistosomamansoni) |
PF00349(Hexokinase_1)PF03727(Hexokinase_2) | 5 | THR A 234ASN A 235TYR A 293GLY A 262LEU A 270 | NoneGLC A 501 (-3.8A)NoneNoneNone | 1.40A | 3sfuB-1bdgA:undetectable | 3sfuB-1bdgA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fxz | GLYCININ G1 (Glycine max) |
PF00190(Cupin_1) | 5 | THR A 66ASN A 67GLY A 68ASP A 148LEU A 338 | None | 1.37A | 3sfuB-1fxzA:undetectable | 3sfuB-1fxzA:21.21 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1khw | RNA-DIRECTED RNAPOLYMERASE (Rabbithemorrhagicdisease virus) |
PF00680(RdRP_1) | 7 | ASP A 255ASN A 317TYR A 352GLY A 353ASP A 354ASP A 355LEU A 402 | NoneNoneNoneNone MN A 601 ( 2.3A) MN A 601 (-4.0A)None | 0.42A | 3sfuB-1khwA:37.5 | 3sfuB-1khwA:32.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oa1 | HYDROXYLAMINEREDUCTASE (Desulfovibriovulgaris) |
PF03063(Prismane) | 5 | ASN A 74TYR A 334GLY A 333ASP A 76LEU A 323 | None | 1.46A | 3sfuB-1oa1A:undetectable | 3sfuB-1oa1A:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qfw | ANTIBODY (ANTI ALPHASUBUNIT) (HEAVYCHAIN)ANTIBODY (ANTI ALPHASUBUNIT) (LIGHTCHAIN) (Mus musculus) |
PF07686(V-set) | 5 | ASP L 9THR L 89TYR L 91GLY L 107LEU H 45 | None | 1.40A | 3sfuB-1qfwL:undetectable | 3sfuB-1qfwL:12.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1raj | GENOME POLYPROTEIN (Enterovirus C) |
PF00680(RdRP_1) | 7 | ASP A 238ASN A 297TYR A 326GLY A 327ASP A 328ASP A 329LEU A 374 | None | 0.66A | 3sfuB-1rajA:19.6 | 3sfuB-1rajA:23.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rdr | POLIOVIRUS 3DPOLYMERASE (Enterovirus C) |
PF00680(RdRP_1) | 7 | ASP A 238ASN A 297TYR A 326GLY A 327ASP A 328ASP A 329LEU A 374 | NoneNoneNoneNoneNone CA A 501 (-3.4A)None | 0.66A | 3sfuB-1rdrA:23.3 | 3sfuB-1rdrA:25.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s4f | RNA-DEPENDENT RNAPOLYMERASE (Pestivirus A) |
PF00998(RdRP_3) | 5 | ASP A 350ASN A 414GLY A 447ASP A 448ASP A 449 | None | 0.91A | 3sfuB-1s4fA:27.5 | 3sfuB-1s4fA:23.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1sh2 | RNA POLYMERASE (Norwalk virus) |
PF00680(RdRP_1) | 7 | ASP A 247ASN A 309GLY A 342ASP A 343ASP A 344LEU A 391ARG A 392 | None | 0.79A | 3sfuB-1sh2A:49.7 | 3sfuB-1sh2A:57.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1sh2 | RNA POLYMERASE (Norwalk virus) |
PF00680(RdRP_1) | 7 | ASP A 247ASN A 309TYR A 341GLY A 342ASP A 343ASP A 344LEU A 391 | None | 0.43A | 3sfuB-1sh2A:49.7 | 3sfuB-1sh2A:57.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tp7 | GENOME POLYPROTEIN (Rhinovirus A) |
PF00680(RdRP_1) | 7 | ASP A 239ASN A 296TYR A 325GLY A 326ASP A 327ASP A 328LEU A 373 | None | 0.56A | 3sfuB-1tp7A:25.7 | 3sfuB-1tp7A:27.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xr5 | GENOME POLYPROTEIN (Rhinovirus B) |
PF00680(RdRP_1) | 7 | ASP A 238ASN A 296TYR A 325GLY A 326ASP A 327ASP A 328LEU A 373 | NoneNoneNoneNone SM A 901 (-2.6A) SM A 901 (-3.0A)None | 0.75A | 3sfuB-1xr5A:30.9 | 3sfuB-1xr5A:27.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xr6 | GENOME POLYPROTEIN (Rhinovirus A) |
PF00680(RdRP_1) | 7 | ASP A 239ASN A 296TYR A 325GLY A 326ASP A 327ASP A 328LEU A 373 | None | 0.59A | 3sfuB-1xr6A:30.9 | 3sfuB-1xr6A:25.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xup | GLYCEROL KINASE (Enterococcuscasseliflavus) |
PF00370(FGGY_N)PF02782(FGGY_C) | 5 | ASP O 167THR O 81ASN O 82GLY O 245LEU O 251 | None | 1.48A | 3sfuB-1xupO:undetectable | 3sfuB-1xupO:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aqx | PREDICTED: INOSITOL1,4,5-TRISPHOSPHATE3-KINASE B (Mus musculus) |
PF03770(IPK) | 5 | ASP A 930ASN A 927GLY A 924ASP A 926LEU A 861 | None | 1.36A | 3sfuB-2aqxA:undetectable | 3sfuB-2aqxA:17.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cjq | RNA-DIRECTED RNAPOLYMERASE (Pestivirus A) |
PF00998(RdRP_3) | 5 | ASP A 350ASN A 414GLY A 447ASP A 448ASP A 449 | None | 0.94A | 3sfuB-2cjqA:24.3 | 3sfuB-2cjqA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d7s | RNA-DEPENDENT RNAPOLYMERASE (Foot-and-mouthdisease virus) |
PF00680(RdRP_1) | 7 | ASP A 245ASN A 307TYR A 336GLY A 337ASP A 338ASP A 339LEU A 386 | None | 0.63A | 3sfuB-2d7sA:32.1 | 3sfuB-2d7sA:25.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d7s | RNA-DEPENDENT RNAPOLYMERASEVPG1 PROTEIN (Foot-and-mouthdisease virus) |
PF00680(RdRP_1)no annotation | 5 | THR A 308ASN A 307GLY A 337LEU A 386ARG B1011 | None | 1.14A | 3sfuB-2d7sA:32.1 | 3sfuB-2d7sA:25.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dfj | DIADENOSINETETRAPHOSPHATASE (Shigellaflexneri) |
PF00149(Metallophos) | 5 | ASP A 37THR A 181ASN A 65ASP A 67LEU A 143 | MN A1001 ( 3.0A)None MN A1001 (-2.6A)NoneNone | 1.48A | 3sfuB-2dfjA:undetectable | 3sfuB-2dfjA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dwu | GLUTAMATE RACEMASE (Bacillusanthracis) |
PF01177(Asp_Glu_race) | 5 | THR A 242ASN A 41GLY A 39ASP A 14LEU A 65 | NoneNoneNoneDGL A 278 (-3.6A)None | 1.41A | 3sfuB-2dwuA:undetectable | 3sfuB-2dwuA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eae | ALPHA-FUCOSIDASE (Bifidobacteriumbifidum) |
PF14498(Glyco_hyd_65N_2) | 5 | THR A 412ASN A 411GLY A 405ASP A 406LEU A 78 | None | 1.49A | 3sfuB-2eaeA:undetectable | 3sfuB-2eaeA:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hcs | RNA-DIRECTED RNAPOLYMERASE (NS5) (West Nile virus) |
PF00972(Flavi_NS5) | 5 | ASP A 541ASN A 613GLY A 667ASP A 668ASP A 669 | None | 0.77A | 3sfuB-2hcsA:16.9 | 3sfuB-2hcsA:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2igi | OLIGORIBONUCLEASE (Escherichiacoli) |
PF00929(RNase_T) | 5 | ASP A 58THR A 15ASN A 61GLY A 16ASP A 18 | None | 1.28A | 3sfuB-2igiA:undetectable | 3sfuB-2igiA:15.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ijd | PICORNAIN 3C,RNA-DIRECTED RNAPOLYMERASE (Enterovirus C) |
PF00548(Peptidase_C3)PF00680(RdRP_1) | 7 | ASP 1 421ASN 1 480TYR 1 509GLY 1 510ASP 1 511ASP 1 512LEU 1 557 | None | 0.59A | 3sfuB-2ijd1:31.1 | 3sfuB-2ijd1:23.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uut | RNA-DIRECTED RNAPOLYMERASE (Sapporo virus) |
PF00680(RdRP_1) | 6 | ASP A 247ASN A 309TYR A 345GLY A 346ASP A 348LEU A 387 | None | 0.70A | 3sfuB-2uutA:38.9 | 3sfuB-2uutA:29.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zxq | ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE (Bifidobacteriumlongum) |
PF12905(Glyco_hydro_101)PF17451(Glyco_hyd_101C) | 5 | THR A1272ASN A1273GLY A1274ASP A1442ASP A1322 | NoneMPD A1695 (-4.4A)MPD A1695 ( 3.2A) MN A 4 (-2.3A)None | 1.47A | 3sfuB-2zxqA:undetectable | 3sfuB-2zxqA:17.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n6n | RNA-DEPENDENT RNAPOLYMERASE (Enterovirus A) |
PF00680(RdRP_1) | 7 | ASP A 238ASN A 298TYR A 327GLY A 328ASP A 329ASP A 330LEU A 375 | BUP A 464 (-3.2A)NoneNoneNoneBUP A 464 ( 4.1A)NoneNone | 0.53A | 3sfuB-3n6nA:30.5 | 3sfuB-3n6nA:26.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p91 | PROLIFERATING CELLNUCLEAR ANTIGEN (Entamoebahistolytica) |
PF00705(PCNA_N)PF02747(PCNA_C) | 5 | ASP A 31THR A 28ASN A 29GLY A 71LEU A 117 | None | 1.33A | 3sfuB-3p91A:undetectable | 3sfuB-3p91A:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tr8 | OLIGORIBONUCLEASE (Coxiellaburnetii) |
PF00929(RNase_T) | 5 | ASP A 59THR A 16ASN A 62GLY A 17ASP A 19 | None | 1.33A | 3sfuB-3tr8A:undetectable | 3sfuB-3tr8A:16.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wq1 | ENDOGLUCANASE A (Pyrococcusfuriosus) |
PF01670(Glyco_hydro_12) | 5 | ASN A 132TYR A 130GLY A 131ASP A 284LEU A 310 | CA A 402 (-3.2A)NoneNoneNoneNone | 1.48A | 3sfuB-3wq1A:undetectable | 3sfuB-3wq1A:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b61 | ALGINATE PRODUCTIONPROTEIN ALGE (Pseudomonasaeruginosa) |
PF13372(Alginate_exp) | 5 | ASP A 102THR A 163ASN A 164LEU A 197ARG A 119 | None | 1.33A | 3sfuB-4b61A:undetectable | 3sfuB-4b61A:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bf5 | ALANINE RACEMASE (Aeromonashydrophila) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 5 | THR A 350ASN A 349GLY A 318ASP A 321LEU A 369 | None | 1.50A | 3sfuB-4bf5A:undetectable | 3sfuB-4bf5A:23.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c18 | TSI2 (Pseudomonasaeruginosa) |
no annotation | 5 | ASP A 49TYR A 44GLY A 43ASP A 45LEU A 22 | None | 1.31A | 3sfuB-4c18A:undetectable | 3sfuB-4c18A:10.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k6m | POLYPROTEIN (Japaneseencephalitisvirus) |
PF00972(Flavi_NS5)PF01728(FtsJ) | 5 | ASP A 541ASN A 613GLY A 667ASP A 668ASP A 669 | None | 0.86A | 3sfuB-4k6mA:24.6 | 3sfuB-4k6mA:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mtp | RNA DEPENDENT RNAPOLYMERASE (Japaneseencephalitisvirus) |
PF00972(Flavi_NS5) | 5 | ASP A 541ASN A 613GLY A 667ASP A 668ASP A 669 | ASP A 541 ( 0.6A)ASN A 613 ( 0.6A)GLY A 667 ( 0.0A)ASP A 668 ( 0.6A)ASP A 669 ( 0.6A) | 1.01A | 3sfuB-4mtpA:21.6 | 3sfuB-4mtpA:22.02 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4nru | RNA DEPENDENT RNAPOLYMERASE (Norwalk virus) |
PF00680(RdRP_1) | 8 | ASP A 247THR A 306ASN A 309TYR A 341GLY A 342ASP A 343ASP A 344LEU A 391 | NoneNoneNone2NG A1101 ( 4.8A)NoneNone MG A1102 (-3.4A)2NG A1101 ( 4.1A) | 0.27A | 3sfuB-4nruA:56.7 | 3sfuB-4nruA:99.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nz0 | GENOME POLYPROTEIN (Cardiovirus A) |
PF00680(RdRP_1) | 7 | ASP A 240ASN A 302TYR A 331GLY A 332ASP A 333ASP A 334LEU A 380 | None | 0.63A | 3sfuB-4nz0A:32.4 | 3sfuB-4nz0A:27.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zpd | RNA-DIRECTED RNAPOLYMERASE (Enterovirus B) |
PF00680(RdRP_1) | 7 | ASP A 238ASN A 298TYR A 327GLY A 328ASP A 329ASP A 330LEU A 375 | None | 0.61A | 3sfuB-4zpdA:31.4 | 3sfuB-4zpdA:26.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ax7 | PYRUVYL TRANSFERASE1 (Schizosaccharomycespombe) |
PF04230(PS_pyruv_trans) | 5 | ASN A 160GLY A 158ASP A 106LEU A 338ARG A 337 | None | 1.42A | 3sfuB-5ax7A:undetectable | 3sfuB-5ax7A:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cy4 | OLIGORIBONUCLEASE (Acinetobacterbaumannii) |
PF00929(RNase_T) | 5 | ASP A 60THR A 17ASN A 63GLY A 18ASP A 20 | None | 1.39A | 3sfuB-5cy4A:undetectable | 3sfuB-5cy4A:16.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cyr | RNA-DEPENDENT RNAPOLYMERASE (Thosea asignavirus) |
no annotation | 7 | ASP B 374THR B 444TYR B 349GLY B 350ASP B 351ASP B 352LEU B 513 | NoneSO4 B 702 (-3.4A)NoneNoneATP B 701 (-2.4A)ATP B 701 (-3.5A)None | 0.77A | 3sfuB-5cyrB:8.9 | 3sfuB-5cyrB:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cyr | RNA-DEPENDENT RNAPOLYMERASE (Thosea asignavirus) |
no annotation | 5 | THR B 448TYR B 349ASP B 351ASP B 352LEU B 513 | NoneNoneATP B 701 (-2.4A)ATP B 701 (-3.5A)None | 1.41A | 3sfuB-5cyrB:8.9 | 3sfuB-5cyrB:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i61 | POTENTIALRNA-DEPENDENT RNAPOLYMERASE (Humanpicobirnavirus) |
no annotation | 5 | ASP B 266GLY B 358ASP B 359ASP B 360LEU B 399 | None | 0.25A | 3sfuB-5i61B:22.3 | 3sfuB-5i61B:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i61 | POTENTIALRNA-DEPENDENT RNAPOLYMERASE (Humanpicobirnavirus) |
no annotation | 5 | THR B 332GLY B 358ASP B 359ASP B 360LEU B 399 | None | 1.31A | 3sfuB-5i61B:22.3 | 3sfuB-5i61B:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iq6 | RNA DEPENDENT RNAPOLYMERASE (Dengue virus) |
PF00972(Flavi_NS5) | 5 | ASP A 538ASN A 609GLY A 662ASP A 663ASP A 664 | None | 0.79A | 3sfuB-5iq6A:21.3 | 3sfuB-5iq6A:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k5m | RNA DEPENDENT RNAPOLYMERASE (Dengue virus) |
PF00972(Flavi_NS5) | 5 | ASP A 539ASN A 610GLY A 662ASP A 663ASP A 664 | None | 1.00A | 3sfuB-5k5mA:21.1 | 3sfuB-5k5mA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5odr | HETERODISULFIDEREDUCTASE, SUBUNIT A (Methanothermococcusthermolithotrophicus) |
PF07992(Pyr_redox_2)PF13187(Fer4_9) | 5 | THR A 169ASN A 211GLY A 163ASP A 164ASP A 161 | None | 1.33A | 3sfuB-5odrA:undetectable | 3sfuB-5odrA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tmh | POLYPROTEIN (Zika virus) |
PF00972(Flavi_NS5)PF01728(FtsJ) | 5 | ASP A 540ASN A 612GLY A 664ASP A 665ASP A 666 | None | 0.95A | 3sfuB-5tmhA:22.3 | 3sfuB-5tmhA:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v96 | S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE (Naegleriafowleri) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | THR A 200GLY A 137ASP A 139LEU A 386ARG A 385 | NAD A 501 (-3.6A)PO4 A 503 ( 4.5A)EDO A 512 (-3.3A)NAD A 501 (-3.9A)EDO A 509 (-3.6A) | 1.32A | 3sfuB-5v96A:undetectable | 3sfuB-5v96A:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x6x | MRNA CAPPING ENZYMEP5 (Rice dwarfvirus) |
no annotation | 5 | ASN C 507TYR C 565GLY C 568ASP C 566LEU C 797 | None | 1.43A | 3sfuB-5x6xC:undetectable | 3sfuB-5x6xC:9.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xe0 | GENOME POLYPROTEIN (Enterovirus D) |
PF00680(RdRP_1) | 7 | ASP A 234ASN A 293TYR A 322GLY A 323ASP A 324ASP A 325LEU A 370 | GTP A 501 (-2.6A)NoneNoneNoneGTP A 501 ( 4.2A)NoneNone | 0.63A | 3sfuB-5xe0A:31.3 | 3sfuB-5xe0A:27.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y6r | GENOME POLYPROTEIN (Pestivirus C) |
no annotation | 5 | ASP A 350ASN A 414GLY A 447ASP A 448ASP A 449 | GOL A 732 (-4.1A)NoneNoneNoneNone | 0.86A | 3sfuB-5y6rA:23.9 | 3sfuB-5y6rA:10.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ykd | D-HYDANTOINASE/DIHYDROPYRIMIDINASE (Pseudomonasaeruginosa) |
no annotation | 5 | ASP A 414THR A 282TYR A 286GLY A 285LEU A 270 | None | 1.25A | 3sfuB-5ykdA:undetectable | 3sfuB-5ykdA:11.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f3m | - (-) |
no annotation | 5 | THR B 193ASN B 197GLY B 389ASP B 388LEU B 41 | None | 0.95A | 3sfuB-6f3mB:undetectable | 3sfuB-6f3mB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f3m | - (-) |
no annotation | 5 | THR B 193ASN B 197GLY B 389ASP B 388LEU B 396 | None | 1.37A | 3sfuB-6f3mB:undetectable | 3sfuB-6f3mB:undetectable |