SIMILAR PATTERNS OF AMINO ACIDS FOR 3SEL_X_DXCX75

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)

(Escherichia
coli) 		PF00117
(GATase)
PF00988
(CPSase_sm_chain) 		4 ILE B1705
LEU B1709
PHE B1870
GLY B1735
 None
 0.97A 3selX-1a9xB:
undetectable		 3selX-1a9xB:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b35 PROTEIN (CRICKET
PARALYSIS VIRUS,
VP1)
PROTEIN (CRICKET
PARALYSIS VIRUS,
VP3)

(Cricket
paralysis
virus;
Cricket
paralysis virus) 		PF08762
(CRPV_capsid)
no annotation 		4 ILE A  45
LEU C  56
PHE C 114
GLY C 248
 None
 1.05A 3selX-1b35A:
undetectable		 3selX-1b35A:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)

(Thermotoga
maritima) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		4 ILE A 246
LEU A 257
PHE A 217
GLY A 221
 None
 1.04A 3selX-1b3bA:
undetectable		 3selX-1b3bA:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cm8 PHOSPHORYLATED MAP
KINASE P38-GAMMA

(Homo sapiens) 		PF00069
(Pkinase) 		4 ILE A 169
LEU A 159
MET A 216
GLY A 213
 None
 0.87A 3selX-1cm8A:
undetectable		 3selX-1cm8A:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cqi PROTEIN
(SUCCINYL-COA
SYNTHETASE BETA
CHAIN)

(Escherichia
coli) 		PF00549
(Ligase_CoA)
PF08442
(ATP-grasp_2) 		4 ILE B 180
LEU B 184
PHE B  12
GLY B 214
 None
 0.82A 3selX-1cqiB:
undetectable		 3selX-1cqiB:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g0v PROTEINASE A

(Saccharomyces
cerevisiae) 		PF00026
(Asp) 		4 ILE A 221
LEU A 223
PHE A 194
GLY A 196
 None
 0.90A 3selX-1g0vA:
undetectable		 3selX-1g0vA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j5s URONATE ISOMERASE

(Thermotoga
maritima) 		PF02614
(UxaC) 		4 LEU A 289
PHE A 327
LYS A 278
GLY A 277
 None
 0.81A 3selX-1j5sA:
undetectable		 3selX-1j5sA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kb0 QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Comamonas
testosteroni) 		PF13360
(PQQ_2)
PF13442
(Cytochrome_CBB3) 		4 ILE A 673
LEU A 582
LYS A 663
GLY A 585
 None
 1.04A 3selX-1kb0A:
undetectable		 3selX-1kb0A:
7.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kfw CHITINASE B

(Arthrobacter
sp. TAD20) 		PF00704
(Glyco_hydro_18) 		4 ILE A  51
LEU A  39
PHE A  34
GLY A 416
 None
 0.83A 3selX-1kfwA:
undetectable		 3selX-1kfwA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oqj GLUCOCORTICOID
MODULATORY ELEMENT
BINDING PROTEIN-1

(Homo sapiens) 		PF01342
(SAND) 		4 ILE A  97
LEU A 156
PHE A 111
GLY A 115
 None
 0.88A 3selX-1oqjA:
undetectable		 3selX-1oqjA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pw4 GLYCEROL-3-PHOSPHATE
TRANSPORTER

(Escherichia
coli) 		PF07690
(MFS_1) 		4 ILE A 357
LEU A 268
MET A 418
GLY A 416
 None
 0.97A 3selX-1pw4A:
undetectable		 3selX-1pw4A:
9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE

(Salmonella
enterica) 		PF06180
(CbiK) 		4 ILE A 244
LEU A 127
MET A 143
GLY A 144
 None
 0.97A 3selX-1qgoA:
undetectable		 3selX-1qgoA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wz2 LEUCYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1) 		4 ILE A 760
LEU A 764
LYS A 808
PHE A 711
 None
 0.96A 3selX-1wz2A:
undetectable		 3selX-1wz2A:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yi7 BETA-XYLOSIDASE,
FAMILY 43 GLYCOSYL
HYDROLASE

(Clostridium
acetobutylicum) 		PF04616
(Glyco_hydro_43) 		4 ILE A 516
LEU A 372
PHE A 380
GLY A 512
 None
 0.86A 3selX-1yi7A:
undetectable		 3selX-1yi7A:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zbp HYPOTHETICAL PROTEIN
VPA1032

(Vibrio
parahaemolyticus) 		PF07024
(ImpE) 		4 ILE A 156
LEU A 158
PHE A 194
GLY A 200
 None
 1.01A 3selX-1zbpA:
undetectable		 3selX-1zbpA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zmo HALOHYDRIN
DEHALOGENASE

(Arthrobacter
sp. AD2) 		PF13561
(adh_short_C2) 		4 ILE A 130
LEU A 223
LYS A 138
PHE A 236
 None
 1.01A 3selX-1zmoA:
undetectable		 3selX-1zmoA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cmh SPERMIDINE SYNTHASE

(Helicobacter
pylori) 		PF01564
(Spermine_synth)
PF17284
(Spermine_synt_N) 		4 ILE A  78
LEU A  86
MET A  65
GLY A  66
 None
 0.96A 3selX-2cmhA:
undetectable		 3selX-2cmhA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cyc TYROSYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00579
(tRNA-synt_1b) 		4 ILE A 263
LEU A  52
LYS A 114
GLY A 110
 None
 1.03A 3selX-2cycA:
undetectable		 3selX-2cycA:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d3t FATTY OXIDATION
COMPLEX ALPHA
SUBUNIT

(Pseudomonas
fragi) 		PF00378
(ECH_1)
PF00725
(3HCDH)
PF02737
(3HCDH_N) 		4 ILE A  95
LEU A  40
PHE A  32
GLY A 118
 None
 0.87A 3selX-2d3tA:
undetectable		 3selX-2d3tA:
6.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dmg KIAA1228 PROTEIN

(Homo sapiens) 		PF00168
(C2) 		4 ILE A  37
LEU A 111
LYS A  68
GLY A 101
 None
 0.91A 3selX-2dmgA:
undetectable		 3selX-2dmgA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e6p OBSCURIN-LIKE
PROTEIN 1

(Homo sapiens) 		PF07679
(I-set) 		4 LEU A  69
LYS A  17
PHE A  80
GLY A  78
 None
 1.02A 3selX-2e6pA:
undetectable		 3selX-2e6pA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fgc ACETOLACTATE
SYNTHASE, SMALL
SUBUNIT

(Thermotoga
maritima) 		PF01842
(ACT)
PF10369
(ALS_ss_C) 		4 ILE A 174
LYS A 158
PHE A 162
GLY A 138
 None
 0.68A 3selX-2fgcA:
undetectable		 3selX-2fgcA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fvg ENDOGLUCANASE

(Thermotoga
maritima) 		PF05343
(Peptidase_M42) 		5 ILE A  89
LEU A  90
LYS A 163
PHE A 149
GLY A  65
 None
None
None
EDO  A 341 (-4.7A)
None
 1.44A 3selX-2fvgA:
undetectable		 3selX-2fvgA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g6t UNCHARACTERIZED
PROTEIN, HOMOLOG
HI1244 FROM
HAEMOPHILUS
INFLUENZAE

(Clostridium
acetobutylicum) 		PF08942
(DUF1919) 		4 ILE A  31
LEU A  20
PHE A  66
GLY A  91
 None
 0.78A 3selX-2g6tA:
undetectable		 3selX-2g6tA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hig 6-PHOSPHO-1-FRUCTOKI
NASE

(Trypanosoma
brucei) 		PF00365
(PFK) 		4 ILE A 208
LEU A 185
PHE A 135
GLY A 134
 None
 1.04A 3selX-2higA:
undetectable		 3selX-2higA:
7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j0a BETA-1,3-N-ACETYLGLU
COSAMINYLTRANSFERASE
MANIC FRINGE

(Mus musculus) 		PF02434
(Fringe) 		4 ILE A  56
LEU A 156
LYS A 169
GLY A 168
 None
 1.00A 3selX-2j0aA:
undetectable		 3selX-2j0aA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ohf GTP-BINDING PROTEIN
9

(Homo sapiens) 		PF01926
(MMR_HSR1)
PF06071
(YchF-GTPase_C) 		4 ILE A  27
LEU A 123
PHE A 263
GLY A 265
 None
 1.02A 3selX-2ohfA:
undetectable		 3selX-2ohfA:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN

(Archaeoglobus
fulgidus) 		PF00005
(ABC_tran) 		4 ILE A  72
LEU A  57
MET A   1
GLY A  23
 None
 0.99A 3selX-2onkA:
undetectable		 3selX-2onkA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qoj INTRON-ENCODED DNA
ENDONUCLEASE I-ANII

(Aspergillus
nidulans) 		PF00961
(LAGLIDADG_1) 		4 ILE Z 131
LEU Z 177
PHE Z 144
GLY Z  15
 None
None
None
MG  Z 603 ( 3.5A)
 1.02A 3selX-2qojZ:
undetectable		 3selX-2qojZ:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vr2 DIHYDROPYRIMIDINASE

(Homo sapiens) 		PF01979
(Amidohydro_1) 		4 ILE A 405
LEU A  52
LYS A 392
GLY A 444
 None
 0.89A 3selX-2vr2A:
undetectable		 3selX-2vr2A:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2woz KELCH REPEAT AND BTB
DOMAIN-CONTAINING
PROTEIN 10

(Rattus
norvegicus) 		PF01344
(Kelch_1) 		4 ILE A 443
PHE A 488
LYS A 455
GLY A 454
 None
 1.00A 3selX-2wozA:
undetectable		 3selX-2wozA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo sapiens) 		PF00079
(Serpin) 		5 ILE A 116
LEU A 114
LYS A 125
PHE A 126
GLY A  63
 None
 1.11A 3selX-2xn6A:
undetectable		 3selX-2xn6A:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xvn ASPERGILLUS
FUMIGATUS CHITINASE
A1

(Aspergillus
fumigatus) 		PF00704
(Glyco_hydro_18) 		4 ILE A  61
LEU A 119
PHE A 161
MET A 104
 None
 0.96A 3selX-2xvnA:
undetectable		 3selX-2xvnA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bji PROTO-ONCOGENE VAV

(Homo sapiens) 		PF00130
(C1_1)
PF00169
(PH)
PF00621
(RhoGEF) 		4 ILE A 433
LEU A 431
MET A 496
LYS A 492
 None
 1.04A 3selX-3bjiA:
undetectable		 3selX-3bjiA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c3v ARACHIN ARAH3
ISOFORM

(Arachis
hypogaea) 		PF00190
(Cupin_1) 		4 ILE A  92
LEU A 166
PHE A 150
GLY A  97
 None
 1.04A 3selX-3c3vA:
undetectable		 3selX-3c3vA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cm0 ADENYLATE KINASE

(Thermus
thermophilus) 		PF00406
(ADK) 		4 ILE A  81
LEU A  24
LYS A 165
GLY A 185
 None
 1.01A 3selX-3cm0A:
undetectable		 3selX-3cm0A:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3coi MITOGEN-ACTIVATED
PROTEIN KINASE 13

(Homo sapiens) 		PF00069
(Pkinase) 		4 ILE A 166
LEU A 156
MET A 213
GLY A 210
 None
 0.78A 3selX-3coiA:
undetectable		 3selX-3coiA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ez1 AMINOTRANSFERASE
MOCR FAMILY

(Deinococcus
geothermalis) 		PF12897
(Aminotran_MocR) 		4 ILE A 253
LEU A 306
PHE A 295
GLY A  44
 None
 0.74A 3selX-3ez1A:
undetectable		 3selX-3ez1A:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f4k PUTATIVE
METHYLTRANSFERASE

(Bacteroides
thetaiotaomicron) 		PF13649
(Methyltransf_25) 		4 ILE A  75
LEU A 108
MET A 133
GLY A 132
 None
 1.03A 3selX-3f4kA:
undetectable		 3selX-3f4kA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fmb DIMERIC PROTEIN OF
UNKNOWN FUNCTION AND
FERREDOXIN-LIKE FOLD

(Bacteroides
fragilis) 		PF07876
(Dabb) 		4 ILE A  43
LEU A  59
LYS A  83
GLY A  82
 None
SO4  A 100 ( 4.8A)
None
None
 0.92A 3selX-3fmbA:
undetectable		 3selX-3fmbA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fs5 UNCHARACTERIZED
PROTEIN YGR203W

(Saccharomyces
cerevisiae) 		PF00581
(Rhodanese) 		4 ILE A  48
LEU A  17
PHE A  33
GLY A  24
 None
 1.04A 3selX-3fs5A:
undetectable		 3selX-3fs5A:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g85 TRANSCRIPTIONAL
REGULATOR (LACI
FAMILY)

(Clostridium
acetobutylicum) 		PF13377
(Peripla_BP_3) 		4 ILE A 219
LEU A 188
PHE A 247
GLY A 169
 None
 0.84A 3selX-3g85A:
undetectable		 3selX-3g85A:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hzb CARBOHYDRATE BINDING
PROTEIN

(Flavobacterium
johnsoniae) 		no annotation 4 ILE A  82
LEU A  18
LYS A   7
GLY A  32
 None
 0.97A 3selX-3hzbA:
undetectable		 3selX-3hzbA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ile PUTATIVE
UNCHARACTERIZED
PROTEIN

(Acidianus
filamentous
virus 1) 		PF11646
(DUF3258) 		4 ILE A 102
LEU A 112
PHE A  71
GLY A  59
 None
 0.95A 3selX-3ileA:
undetectable		 3selX-3ileA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j7y BL19

(Homo sapiens) 		PF01245
(Ribosomal_L19) 		4 ILE Q 136
LEU Q 190
LYS Q 241
GLY Q 242
 None
 1.05A 3selX-3j7yQ:
undetectable		 3selX-3j7yQ:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE

(Parabacteroides
distasonis) 		PF13483
(Lactamase_B_3) 		4 ILE A 130
LEU A 116
LYS A 112
GLY A 113
 None
 0.93A 3selX-3kl7A:
undetectable		 3selX-3kl7A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m6a ATP-DEPENDENT
PROTEASE LA 1

(Bacillus
subtilis) 		PF00004
(AAA)
PF05362
(Lon_C) 		4 ILE A 742
LEU A 717
MET A 701
GLY A 700
 None
 1.03A 3selX-3m6aA:
undetectable		 3selX-3m6aA:
8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pua PHD FINGER PROTEIN 2

(Homo sapiens) 		PF02373
(JmjC) 		4 ILE A 239
LEU A 330
LYS A 235
PHE A 332
 None
 0.87A 3selX-3puaA:
undetectable		 3selX-3puaA:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qb8 A654L PROTEIN

(Paramecium
bursaria
Chlorella virus
1) 		PF00583
(Acetyltransf_1) 		4 ILE A 133
LEU A 129
PHE A 157
GLY A 146
 None
 0.97A 3selX-3qb8A:
undetectable		 3selX-3qb8A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3suz AMYLOID BETA A4
PRECURSOR
PROTEIN-BINDING
FAMILY A MEMBER 2

(Rattus
norvegicus) 		PF00595
(PDZ)
PF00640
(PID) 		4 ILE A 652
LEU A 613
MET A 602
GLY A 581
 None
 1.05A 3selX-3suzA:
undetectable		 3selX-3suzA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u4v TELOMERASE-ASSOCIATE
D PROTEIN 82

(Tetrahymena
thermophila) 		PF01336
(tRNA_anti-codon) 		4 LEU A 219
LYS A 211
PHE A 228
GLY A 287
 None
 0.55A 3selX-3u4vA:
undetectable		 3selX-3u4vA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wzi UNCHARACTERIZED
PROTEIN AF_1864

(Archaeoglobus
fulgidus) 		PF09620
(Cas_csx3) 		4 ILE A  30
LEU A  55
PHE A  16
GLY A  47
 None
None
None
U  C   2 ( 3.6A)
 0.92A 3selX-3wziA:
undetectable		 3selX-3wziA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4av6 K(+)-STIMULATED
PYROPHOSPHATE-ENERGI
ZED SODIUM PUMP

(Thermotoga
maritima) 		PF03030
(H_PPase) 		4 LEU A 325
PHE A 501
MET A 447
GLY A 373
 None
 1.01A 3selX-4av6A:
undetectable		 3selX-4av6A:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b7g CATALASE

(Corynebacterium
glutamicum) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		4 ILE A 350
LEU A 346
PHE A 215
GLY A 211
 None
 0.97A 3selX-4b7gA:
undetectable		 3selX-4b7gA:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dg8 PA1221

(Pseudomonas
aeruginosa) 		PF00501
(AMP-binding) 		4 ILE A  89
LEU A  56
MET A  34
GLY A 227
 None
 1.05A 3selX-4dg8A:
undetectable		 3selX-4dg8A:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e8d GLYCOSYL HYDROLASE,
FAMILY 35

(Streptococcus
pneumoniae) 		PF01301
(Glyco_hydro_35) 		4 ILE A 579
LYS A 588
PHE A 543
GLY A 529
 None
 1.03A 3selX-4e8dA:
undetectable		 3selX-4e8dA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4en2 AP-1 COMPLEX SUBUNIT
MU-1

(Mus musculus) 		no annotation 4 ILE M 253
LEU M 214
LYS M 199
GLY M 196
 None
 0.87A 3selX-4en2M:
undetectable		 3selX-4en2M:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f1h TYROSYL-DNA
PHOSPHODIESTERASE 2

(Danio rerio) 		PF03372
(Exo_endo_phos) 		4 ILE A 219
LEU A 217
PHE A 268
GLY A 270
 None
 0.95A 3selX-4f1hA:
undetectable		 3selX-4f1hA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f4c MULTIDRUG RESISTANCE
PROTEIN PGP-1

(Caenorhabditis
elegans) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane) 		4 ILE A 460
LEU A 464
LYS A 413
GLY A 414
 None
 1.05A 3selX-4f4cA:
undetectable		 3selX-4f4cA:
4.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gbj 6-PHOSPHOGLUCONATE
DEHYDROGENASE
NAD-BINDING

(Dyadobacter
fermentans) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 ILE A 149
LEU A  21
PHE A   7
GLY A  14
 None
 1.00A 3selX-4gbjA:
undetectable		 3selX-4gbjA:
15.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hc3 PPCA

(Geobacter
sulfurreducens) 		no annotation 8 ILE A   4
LEU A   6
LYS A  33
LYS A  37
PHE A  41
MET A  45
LYS A  49
GLY A  50
 HEM  A  72 (-4.4A)
HEM  A  74 ( 3.7A)
DXC  A  75 ( 4.4A)
DXC  A  75 ( 2.6A)
DXC  A  75 ( 4.3A)
DXC  A  75 (-4.2A)
DXC  A  75 ( 4.1A)
DXC  A  75 ( 3.7A)
 0.39A 3selX-4hc3A:
15.5		 3selX-4hc3A:
97.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hcx ISOCITRATE
DEHYDROGENASE [NADP]

(Mycobacterium
tuberculosis) 		PF00180
(Iso_dh) 		4 ILE A  34
LEU A  38
LYS A 348
GLY A 347
 None
 0.92A 3selX-4hcxA:
undetectable		 3selX-4hcxA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hu8 GH10 XYLANASE

(Globitermes
brachycerastes) 		PF00331
(Glyco_hydro_10)
PF02368
(Big_2) 		4 LEU A 148
LYS A 454
MET A 429
GLY A 431
 None
 0.99A 3selX-4hu8A:
undetectable		 3selX-4hu8A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hwv PECTATE LYASE/AMB
ALLERGEN

(Acidovorax
citrulli) 		PF00544
(Pec_lyase_C) 		5 ILE A 417
LEU A 385
MET A 359
LYS A 337
GLY A 358
 None
 1.14A 3selX-4hwvA:
undetectable		 3selX-4hwvA:
7.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i34 ATP-DEPENDENT CLP
PROTEASE ATP-BINDING
SUBUNIT CLPX

(Escherichia
coli) 		PF07724
(AAA_2)
PF10431
(ClpB_D2-small) 		4 ILE A 305
LEU A 300
PHE A 251
GLY A 249
 None
 0.91A 3selX-4i34A:
undetectable		 3selX-4i34A:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4izg MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME,
N-TERMINAL DOMAIN
PROTEIN

(Paracoccus
denitrificans) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ILE A 308
LEU A 267
LYS A 114
GLY A  47
 None
None
IOD  A 402 (-3.6A)
None
 1.02A 3selX-4izgA:
undetectable		 3selX-4izgA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jx8 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH] FABI

(Escherichia
coli) 		PF13561
(adh_short_C2) 		4 ILE A  59
LEU A  78
LYS A   7
PHE A  85
 None
 1.04A 3selX-4jx8A:
undetectable		 3selX-4jx8A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k59 RNA BINDING PROTEIN
RSMF

(Pseudomonas
aeruginosa) 		PF02599
(CsrA) 		4 ILE A  41
LYS A  22
MET A   4
GLY A   5
 None
 1.03A 3selX-4k59A:
undetectable		 3selX-4k59A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kma GM14141P

(Drosophila
melanogaster) 		PF05076
(SUFU)
PF12470
(SUFU_C) 		4 ILE A 450
LEU A 448
PHE A 422
LYS A 363
 None
 1.01A 3selX-4kmaA:
undetectable		 3selX-4kmaA:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4laf NAD(P)H
DEHYDROGENASE
(QUINONE)

(Pseudomonas sp.
WBC-3) 		PF03358
(FMN_red) 		4 ILE A 145
LEU A 138
PHE A 134
GLY A  81
 None
 0.96A 3selX-4lafA:
undetectable		 3selX-4lafA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mki ENERGY-COUPLING
FACTOR TRANSPORTER
ATP-BINDING PROTEIN
ECFA2

(Caldanaerobacter
subterraneus) 		no annotation 4 ILE B 186
LEU B 183
LYS B  46
MET B 204
 LMT  B 302 ( 4.5A)
None
SO4  B 301 (-2.7A)
None
 1.05A 3selX-4mkiB:
undetectable		 3selX-4mkiB:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o38 CYCLIN-G-ASSOCIATED
KINASE

(Homo sapiens) 		PF00069
(Pkinase) 		4 ILE A 316
LEU A 313
PHE A 152
GLY A 250
 None
 0.96A 3selX-4o38A:
undetectable		 3selX-4o38A:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u8g PUTATIVE
UNCHARACTERIZED
PROTEIN GBS1891

(Streptococcus
agalactiae) 		PF13561
(adh_short_C2) 		4 ILE A 250
LEU A 242
LYS A 171
GLY A 192
 None
 0.89A 3selX-4u8gA:
undetectable		 3selX-4u8gA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wtw INTEGRIN BETA-4

(Homo sapiens) 		PF00041
(fn3) 		4 ILE A1548
LEU A1474
PHE A1466
GLY A1544
 None
 1.05A 3selX-4wtwA:
undetectable		 3selX-4wtwA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x6k ANHYDROSIALIDASE

([Ruminococcus]
gnavus) 		PF13088
(BNR_2) 		4 ILE A 642
LEU A 627
LYS A 299
GLY A 686
 None
 0.76A 3selX-4x6kA:
undetectable		 3selX-4x6kA:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xjn NUCLEOCAPSID

(Mammalian
rubulavirus 5) 		PF00973
(Paramyxo_ncap) 		4 ILE A  99
LEU A  74
LYS A 225
GLY A 226
 None
 0.97A 3selX-4xjnA:
undetectable		 3selX-4xjnA:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aza MALTOSE-BINDING
PERIPLASMIC
PROTEIN,OLIGOSACCHAR
YL TRANSFERASE STT3
SUBUNIT RELATED
PROTEIN

(Escherichia
coli;
Pyrococcus
furiosus) 		PF13416
(SBP_bac_8) 		4 ILE A 132
LEU A 198
LYS A 256
GLY A 191
 None
 0.67A 3selX-5azaA:
undetectable		 3selX-5azaA:
6.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bpt MGC81278 PROTEIN

(Xenopus laevis) 		PF12894
(ANAPC4_WD40)
PF12896
(ANAPC4) 		5 ILE A 103
LEU A  99
PHE A  97
MET A 185
GLY A 184
 None
 1.37A 3selX-5bptA:
undetectable		 3selX-5bptA:
7.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cbk SHHTL5

(Striga
hermonthica) 		PF12697
(Abhydrolase_6) 		4 ILE A  80
LEU A  77
PHE A  91
GLY A  93
 None
 1.00A 3selX-5cbkA:
undetectable		 3selX-5cbkA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cml OSMC FAMILY PROTEIN

(Rhodothermus
marinus) 		PF12146
(Hydrolase_4) 		4 ILE A 106
LEU A 104
LYS A   1
GLY A  58
 None
 1.05A 3selX-5cmlA:
undetectable		 3selX-5cmlA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d27 PHOSPHATIDYLINOSITOL
3,4,5-TRISPHOSPHATE-
DEPENDENT RAC
EXCHANGER 1 PROTEIN

(Homo sapiens) 		PF00169
(PH) 		4 ILE A 361
LEU A 298
LYS A 382
GLY A 276
 None
 0.81A 3selX-5d27A:
undetectable		 3selX-5d27A:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dnw SHKAI2IB

(Striga
hermonthica) 		PF12697
(Abhydrolase_6) 		4 ILE A  80
LEU A  77
PHE A  91
GLY A  93
 None
 1.02A 3selX-5dnwA:
undetectable		 3selX-5dnwA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f9a ADHESIN BINDING
FUCOSYLATED
HISTO-BLOOD GROUP
ANTIGEN,ADHESIN,ADHE
SIN BINDING
FUCOSYLATED
HISTO-BLOOD GROUP
ANTIGEN

(Helicobacter
pylori) 		no annotation 4 ILE A 450
LEU A 454
PHE A 339
GLY A 332
 None
 0.88A 3selX-5f9aA:
undetectable		 3selX-5f9aA:
11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fi0 PHOSPHATIDYLINOSITOL
3,4,5-TRISPHOSPHATE-
DEPENDENT RAC
EXCHANGER 1
PROTEIN,PHOSPHATIDYL
INOSITOL
3,4,5-TRISPHOSPHATE-
DEPENDENT RAC
EXCHANGER 1 PROTEIN

(Homo sapiens) 		PF00169
(PH)
PF00621
(RhoGEF) 		4 ILE A 361
LEU A 298
LYS A 382
GLY A 276
 None
 0.77A 3selX-5fi0A:
undetectable		 3selX-5fi0A:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j0g OXIDOREDUCTASE,SUPER
OXIDE DISMUTASE
[CU-ZN]

(Homo sapiens) 		PF00080
(Sod_Cu) 		4 ILE A  10
LEU A 105
LYS A  48
GLY A  51
 None
 1.01A 3selX-5j0gA:
undetectable		 3selX-5j0gA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j9h ENVELOPMENT
POLYPROTEIN

(Puumala
orthohantavirus) 		PF01561
(Hanta_G2) 		4 ILE A 726
LEU A 948
PHE A 858
GLY A 866
 None
None
None
NAG  A1202 (-4.0A)
 1.01A 3selX-5j9hA:
undetectable		 3selX-5j9hA:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jb3 30S RIBOSOMAL
PROTEIN S9

(Pyrococcus
abyssi) 		PF00380
(Ribosomal_S9) 		4 ILE K  45
LEU K  49
LYS K  23
GLY K  24
 None
None
G  21097 ( 3.7A)
None
 0.93A 3selX-5jb3K:
undetectable		 3selX-5jb3K:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k53 ALDEHYDE
DEFORMYLATING
OXYGENASE

(Oscillatoria
sp.) 		PF11266
(Ald_deCOase) 		4 ILE A 176
LEU A 180
PHE A  87
GLY A  31
 None
None
None
STE  A 502 ( 3.9A)
 1.05A 3selX-5k53A:
undetectable		 3selX-5k53A:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ksd ATPASE 2, PLASMA
MEMBRANE-TYPE

(Arabidopsis
thaliana) 		PF00122
(E1-E2_ATPase)
PF00690
(Cation_ATPase_N)
PF00702
(Hydrolase) 		4 ILE A 497
LEU A 625
MET A 585
GLY A 584
 None
 0.89A 3selX-5ksdA:
undetectable		 3selX-5ksdA:
6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kzs PUTATIVE CELL
SURFACE PROTEIN,
SIMILAR TO
INTERNALIN PROTEINS

(Listeria
monocytogenes) 		PF12354
(Internalin_N)
PF13855
(LRR_8) 		4 ILE A 122
LEU A  93
PHE A  80
LYS A  56
 None
 1.04A 3selX-5kzsA:
undetectable		 3selX-5kzsA:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ltq GREEN FLUORESCENT
PROTEIN BLFP-Y3

(Branchiostoma
lanceolatum) 		PF01353
(GFP) 		4 LEU A  53
LYS A  43
PHE A  20
GLY A  13
 None
 1.01A 3selX-5ltqA:
undetectable		 3selX-5ltqA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii) 		PF12765
(Cohesin_HEAT)
PF12830
(Nipped-B_C) 		4 ILE A 486
LEU A 490
PHE A 504
GLY A 555
 None
 0.81A 3selX-5me3A:
undetectable		 3selX-5me3A:
4.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5npy FLAGELLAR BASAL BODY
PROTEIN

(Helicobacter
pylori) 		no annotation 4 ILE A 352
LEU A 310
PHE A 224
GLY A 280
 None
 1.01A 3selX-5npyA:
undetectable		 3selX-5npyA:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o9g CHROMO
DOMAIN-CONTAINING
PROTEIN 1

(Saccharomyces
cerevisiae) 		no annotation 4 ILE W 691
LEU W 687
LYS W 708
GLY W 735
 None
 0.74A 3selX-5o9gW:
undetectable		 3selX-5o9gW:
3.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oar BETA-HEXOSAMINIDASE
BETA-HEXOSAMINIDASE

(Aspergillus
oryzae;
Aspergillus
oryzae) 		no annotation
no annotation 		4 ILE B 561
LEU A  24
MET B 208
GLY B 207
 None
 0.88A 3selX-5oarB:
undetectable		 3selX-5oarB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oo7 SLA2

(Chaetomium
thermophilum) 		no annotation 4 ILE A 171
LEU A 167
PHE A 140
GLY A 138
 None
 0.91A 3selX-5oo7A:
undetectable		 3selX-5oo7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xcc PROBABLE SURFACE
PROTEIN

(Clostridium
perfringens) 		no annotation 4 ILE A 300
LEU A 398
LYS A 377
GLY A 378
 None
 1.01A 3selX-5xccA:
undetectable		 3selX-5xccA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xhu FERREDOXIN--NADP
REDUCTASE

(Bacillus
subtilis) 		no annotation 4 ILE A  84
LEU A  86
LYS A  45
GLY A  44
 None
None
FAD  A1000 (-2.8A)
FAD  A1000 (-3.3A)
 0.85A 3selX-5xhuA:
undetectable		 3selX-5xhuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y6j NUCLEOPROTEIN

(Tomato spotted
wilt
orthotospovirus) 		PF01533
(Tospo_nucleocap) 		4 ILE A 100
LEU A  96
PHE A  74
GLY A  75
 None
 1.00A 3selX-5y6jA:
undetectable		 3selX-5y6jA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eki CARBONIC ANHYDRASE

(Persephonella
marina) 		no annotation 4 ILE A 162
LEU A 187
PHE A 116
GLY A  84
 None
 0.85A 3selX-6ekiA:
undetectable		 3selX-6ekiA:
undetectable