SIMILAR PATTERNS OF AMINO ACIDS FOR 3S8P_B_SAMB500_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bxk PROTEIN
(DTDP-GLUCOSE
4,6-DEHYDRATASE)


(Escherichia
coli)
PF16363
(GDP_Man_Dehyd)
3 HIS A 130
SER A 167
ASN A 186
None
0.75A 3s8pB-1bxkA:
undetectable
3s8pB-1bxkA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g1a DTDP-D-GLUCOSE
4,6-DEHYDRATASE


(Salmonella
enterica)
PF16363
(GDP_Man_Dehyd)
3 HIS A 129
SER A 174
ASN A 193
None
0.72A 3s8pB-1g1aA:
undetectable
3s8pB-1g1aA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hfu LACCASE 1

(Coprinopsis
cinerea)
PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3)
3 HIS A 451
SER A 349
ASN A  83
CU  A 702 (-3.2A)
None
None
0.74A 3s8pB-1hfuA:
0.0
3s8pB-1hfuA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hr7 MITOCHONDRIAL
PROCESSING PEPTIDASE
ALPHA SUBUNIT
MITOCHONDRIAL
PROCESSING PEPTIDASE
BETA SUBUNIT


(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae)
PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
3 HIS B  98
SER B 391
ASN A 381
None
0.85A 3s8pB-1hr7B:
0.0
3s8pB-1hr7B:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kcw CERULOPLASMIN

(Homo sapiens)
PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3)
3 HIS A 602
SER A 629
ASN A 632
CU  A1054 ( 3.4A)
None
None
0.70A 3s8pB-1kcwA:
0.0
3s8pB-1kcwA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ksp PROTEIN (DNA
POLYMERASE I-KLENOW
FRAGMENT
(E.C.2.7.7.7))


(Escherichia
coli)
PF00476
(DNA_pol_A)
PF01612
(DNA_pol_A_exo1)
3 HIS A 656
SER A 360
ASN A 430
None
0.86A 3s8pB-1kspA:
0.0
3s8pB-1kspA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nfg D-HYDANTOINASE

(Ralstonia
pickettii)
PF00449
(Urease_alpha)
PF01979
(Amidohydro_1)
3 HIS A  59
SER A  64
ASN A 157
ZN  A 501 (-3.5A)
None
None
0.77A 3s8pB-1nfgA:
0.0
3s8pB-1nfgA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o94 TRIMETHYLAMINE
DEHYDROGENASE


(Methylophilus
methylotrophus)
PF00724
(Oxidored_FMN)
PF07992
(Pyr_redox_2)
3 HIS A 592
SER A 595
ASN A 627
None
0.75A 3s8pB-1o94A:
0.0
3s8pB-1o94A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oc2 DTDP-GLUCOSE
4,6-DEHYDRATASE


(Streptococcus
suis)
PF16363
(GDP_Man_Dehyd)
3 HIS A 121
SER A 168
ASN A 187
None
0.85A 3s8pB-1oc2A:
undetectable
3s8pB-1oc2A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pvg DNA TOPOISOMERASE II

(Saccharomyces
cerevisiae)
PF00204
(DNA_gyraseB)
PF02518
(HATPase_c)
3 HIS A 316
SER A 379
ASN A 306
None
0.80A 3s8pB-1pvgA:
undetectable
3s8pB-1pvgA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ta3 XYLANASE INHIBITOR
PROTEIN I
ENDO-1,4-BETA-XYLANA
SE


(Triticum
aestivum;
Aspergillus
nidulans)
PF00704
(Glyco_hydro_18)
PF00331
(Glyco_hydro_10)
3 HIS B  85
SER B  93
ASN A 196
None
0.72A 3s8pB-1ta3B:
undetectable
3s8pB-1ta3B:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6


(Homo sapiens)
PF00326
(Peptidase_S9)
PF00930
(DPPIV_N)
3 HIS A 431
SER A 406
ASN A 434
None
0.66A 3s8pB-1xfdA:
undetectable
3s8pB-1xfdA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
ORPHAN NUCLEAR
RECEPTOR NR1I3


(Homo sapiens;
Mus musculus)
PF00104
(Hormone_recep)
PF00104
(Hormone_recep)
3 HIS E 254
SER E 331
ASN A 377
None
0.67A 3s8pB-1xlsE:
1.5
3s8pB-1xlsE:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zkp HYPOTHETICAL PROTEIN
BA1088


(Bacillus
anthracis)
PF12706
(Lactamase_B_2)
3 HIS A  61
SER A  20
ASN A 177
ZN  A 245 (-3.1A)
ZN  A 246 ( 4.8A)
None
0.85A 3s8pB-1zkpA:
undetectable
3s8pB-1zkpA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zxn DNA TOPOISOMERASE
II, ALPHA ISOZYME


(Homo sapiens)
PF00204
(DNA_gyraseB)
PF02518
(HATPase_c)
3 HIS A 325
SER A 390
ASN A 315
None
0.91A 3s8pB-1zxnA:
undetectable
3s8pB-1zxnA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bi3 PHOSPHOSERINE
AMINOTRANSFERASE


(Bacillus
alcalophilus)
PF00266
(Aminotran_5)
3 HIS A 146
SER A 121
ASN A 151
None
0.77A 3s8pB-2bi3A:
undetectable
3s8pB-2bi3A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d3y URACIL-DNA
GLYCOSYLASE


(Thermus
thermophilus)
PF03167
(UDG)
3 HIS A  63
SER A  77
ASN A 120
None
ACT  A 222 ( 4.2A)
None
0.88A 3s8pB-2d3yA:
undetectable
3s8pB-2d3yA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2flq NITRIC OXIDE
SYNTHASE


(Geobacillus
stearothermophilus)
PF02898
(NO_synthase)
3 HIS A 134
SER A 152
ASN A 253
None
None
ARG  A 376 (-2.9A)
0.87A 3s8pB-2flqA:
undetectable
3s8pB-2flqA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fuq HEPARINASE II
PROTEIN


(Pedobacter
heparinus)
PF07940
(Hepar_II_III)
PF16332
(DUF4962)
3 HIS A 347
SER A 214
ASN A 264
None
0.83A 3s8pB-2fuqA:
undetectable
3s8pB-2fuqA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fz0 V-SNARE COMPONENT OF
THE VACUOLAR SNARE
COMPLEX INVOLVED IN
VESICLE FUSION
INHIBITS
ATP-DEPENDENT CA(2+)
TRANSPORT ACTIVITY
OF PMC1P IN THE
VACUOLAR MEMBRANE
NYV1P


(Saccharomyces
cerevisiae)
PF09426
(Nyv1_N)
3 HIS A  86
SER A  82
ASN A 118
None
0.83A 3s8pB-2fz0A:
undetectable
3s8pB-2fz0A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE


(Anabaena sp.)
PF05996
(Fe_bilin_red)
3 HIS A 121
SER A 156
ASN A 131
None
0.87A 3s8pB-2g18A:
undetectable
3s8pB-2g18A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gko MICROBIAL SERINE
PROTEINASES
SUBTILISIN


(Bacillus
subtilis)
PF00082
(Peptidase_S8)
3 HIS A  71
SER A 252
ASN A 168
PMS  A 601 (-3.1A)
None
PMS  A 601 (-3.0A)
0.87A 3s8pB-2gkoA:
undetectable
3s8pB-2gkoA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ixb ALPHA-N-ACETYLGALACT
OSAMINIDASE


(Elizabethkingia
meningoseptica)
PF01408
(GFO_IDH_MocA)
3 HIS A 299
SER A 250
ASN A 221
None
0.86A 3s8pB-2ixbA:
undetectable
3s8pB-2ixbA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kdk ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR-LIKE
PROTEIN 2


(Homo sapiens)
PF14598
(PAS_11)
3 HIS A 369
SER A 398
ASN A 364
None
0.82A 3s8pB-2kdkA:
undetectable
3s8pB-2kdkA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qt6 LACCASE

(Lentinus
tigrinus)
PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3)
3 HIS A  55
SER A  89
ASN A  12
None
0.69A 3s8pB-2qt6A:
undetectable
3s8pB-2qt6A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qza SECRETED EFFECTOR
PROTEIN


(Salmonella
enterica)
PF13599
(Pentapeptide_4)
PF13979
(SopA_C)
PF13981
(SopA)
3 HIS A 633
SER A 755
ASN A 347
None
0.87A 3s8pB-2qzaA:
undetectable
3s8pB-2qzaA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE


(Achromobacter
xylosoxidans)
PF00394
(Cu-oxidase)
PF07732
(Cu-oxidase_3)
3 HIS A 231
SER A 137
ASN A 207
None
0.76A 3s8pB-2vmjA:
undetectable
3s8pB-2vmjA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wab ENDOGLUCANASE E

(Ruminiclostridium
thermocellum)
PF00657
(Lipase_GDSL)
3 HIS A 310
SER A 157
ASN A 220
BGC  A1338 (-4.0A)
None
None
0.82A 3s8pB-2wabA:
undetectable
3s8pB-2wabA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c7o ENDO-1,4-BETA-XYLANA
SE


(Bacillus
subtilis)
PF03422
(CBM_6)
PF04616
(Glyco_hydro_43)
3 HIS A 305
SER A 310
ASN A  54
None
0.77A 3s8pB-3c7oA:
undetectable
3s8pB-3c7oA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e48 PUTATIVE
NUCLEOSIDE-DIPHOSPHA
TE-SUGAR EPIMERASE


(Staphylococcus
aureus)
PF13460
(NAD_binding_10)
3 HIS A 248
SER A 118
ASN A 112
None
0.89A 3s8pB-3e48A:
undetectable
3s8pB-3e48A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hhs PHENOLOXIDASE
SUBUNIT 2


(Manduca sexta)
PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C)
3 HIS A 219
SER A  86
ASN A 369
CU  A 696 (-3.3A)
None
None
0.70A 3s8pB-3hhsA:
undetectable
3s8pB-3hhsA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i93 DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE


(Mycobacterium
tuberculosis)
PF00692
(dUTPase)
3 HIS A  62
SER A  74
ASN A  77
None
TRS  A 202 (-3.0A)
DUP  A 201 (-3.2A)
0.82A 3s8pB-3i93A:
undetectable
3s8pB-3i93A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mzn GLUCARATE
DEHYDRATASE


(Chromohalobacter
salexigens)
PF13378
(MR_MLE_C)
3 HIS A 335
SER A 343
ASN A 338
None
None
SO4  A 450 ( 4.8A)
0.89A 3s8pB-3mznA:
undetectable
3s8pB-3mznA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nv0 NUCLEAR RNA EXPORT
FACTOR 2
NTF2-RELATED EXPORT
PROTEIN


(Caenorhabditis
elegans;
Caenorhabditis
elegans)
no annotation
PF02136
(NTF2)
3 HIS A 337
SER A 383
ASN B  98
None
None
NA  B 452 (-4.1A)
0.74A 3s8pB-3nv0A:
undetectable
3s8pB-3nv0A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nxl GLUCARATE
DEHYDRATASE


(Burkholderia
lata)
PF13378
(MR_MLE_C)
3 HIS A 359
SER A 367
ASN A 362
MG  A 476 ( 4.5A)
None
CO3  A 477 ( 4.8A)
0.90A 3s8pB-3nxlA:
0.0
3s8pB-3nxlA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pov ORF 37

(Human
gammaherpesvirus
8)
PF01771
(Herpes_alk_exo)
3 HIS A 454
SER A 461
ASN A 213
None
0.85A 3s8pB-3povA:
undetectable
3s8pB-3povA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rr6 PUTATIVE
UNCHARACTERIZED
PROTEIN


(Mycobacteroides
abscessus)
PF01557
(FAA_hydrolase)
PF10370
(DUF2437)
3 HIS A 113
SER A 253
ASN A 190
None
None
PEG  A 266 (-3.9A)
0.85A 3s8pB-3rr6A:
undetectable
3s8pB-3rr6A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s6b METHIONINE
AMINOPEPTIDASE


(Plasmodium
falciparum)
PF00557
(Peptidase_M24)
3 HIS A 284
SER A 330
ASN A 206
None
0.77A 3s8pB-3s6bA:
undetectable
3s8pB-3s6bA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s7i ALLERGEN ARA H 1,
CLONE P41B


(Arachis
hypogaea)
PF00190
(Cupin_1)
3 HIS A 229
SER A 289
ASN A 293
None
0.81A 3s8pB-3s7iA:
undetectable
3s8pB-3s7iA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ui7 CAMP AND
CAMP-INHIBITED CGMP
3',5'-CYCLIC
PHOSPHODIESTERASE
10A


(Homo sapiens)
PF00233
(PDEase_I)
3 HIS A 535
SER A 497
ASN A 543
None
0.84A 3s8pB-3ui7A:
1.2
3s8pB-3ui7A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vax PUTATIVE
UNCHARACTERIZED
PROTEIN DNDA


(Streptomyces
lividans)
PF00266
(Aminotran_5)
3 HIS A  99
SER A 144
ASN A  74
PLP  A 400 (-3.7A)
None
None
0.88A 3s8pB-3vaxA:
undetectable
3s8pB-3vaxA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vrb FLAVOPROTEIN SUBUNIT
OF COMPLEX II
IRON-SULFUR SUBUNIT
OF SUCCINATE
DEHYDROGENASE


(Ascaris suum;
Ascaris suum)
PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C)
PF13085
(Fer2_3)
PF13534
(Fer4_17)
3 HIS A 250
SER A 541
ASN B  77
None
0.63A 3s8pB-3vrbA:
undetectable
3s8pB-3vrbA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1


(Lupinus luteus)
PF00149
(Metallophos)
PF14008
(Metallophos_C)
PF16656
(Pur_ac_phosph_N)
3 HIS A 509
SER A 442
ASN A 490
None
0.81A 3s8pB-3zk4A:
undetectable
3s8pB-3zk4A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zo9 TREHALOSE
SYNTHASE/AMYLASE
TRES


(Mycolicibacterium
smegmatis)
PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C)
3 HIS A 295
SER A 401
ASN A  34
None
0.85A 3s8pB-3zo9A:
undetectable
3s8pB-3zo9A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyn LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 4B


(Mus musculus)
PF00560
(LRR_1)
PF13855
(LRR_8)
3 HIS A 296
SER A 325
ASN A 318
None
0.76A 3s8pB-3zynA:
undetectable
3s8pB-3zynA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyv AOX3

(Mus musculus)
PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C)
3 HIS A 135
SER A  70
ASN A 317
None
0.91A 3s8pB-3zyvA:
undetectable
3s8pB-3zyvA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ade SUCCINYLORNITHINE
TRANSAMINASE


(Escherichia
coli)
PF00202
(Aminotran_3)
3 HIS A  73
SER A 289
ASN A 103
None
0.78A 3s8pB-4adeA:
undetectable
3s8pB-4adeA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4amc GLUCANSUCRASE

(Lactobacillus
reuteri)
PF01473
(CW_binding_1)
PF02324
(Glyco_hydro_70)
3 HIS A1091
SER A1186
ASN A1135
None
0.71A 3s8pB-4amcA:
undetectable
3s8pB-4amcA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4arx PESTICIDAL CRYSTAL
PROTEIN CRY1AC


(Bacillus
thuringiensis)
PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N)
3 HIS A 319
SER A 363
ASN A 270
None
0.89A 3s8pB-4arxA:
undetectable
3s8pB-4arxA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ayj BOGT -
METAL-INDEPENDENT
GLYCOSYLTRANSFERASE


(Bacteroides
ovatus)
PF03414
(Glyco_transf_6)
3 HIS A 122
SER A 159
ASN A 196
GAL  A1233 (-3.5A)
None
None
0.88A 3s8pB-4ayjA:
undetectable
3s8pB-4ayjA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cza NA+/H+ ANTIPORTER,
PUTATIVE


(Pyrococcus
abyssi)
PF00999
(Na_H_Exchanger)
3 HIS A 388
SER A 320
ASN A 314
None
0.82A 3s8pB-4czaA:
0.4
3s8pB-4czaA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fuk METHIONINE
AMINOPEPTIDASE


(Trypanosoma
brucei)
PF00557
(Peptidase_M24)
3 HIS A 299
SER A 345
ASN A 224
None
None
ZN  A 402 ( 4.9A)
0.79A 3s8pB-4fukA:
undetectable
3s8pB-4fukA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g56 HSL7 PROTEIN
MGC81050 PROTEIN


(Xenopus laevis;
Xenopus laevis)
PF05185
(PRMT5)
PF17285
(PRMT5_TIM)
PF17286
(PRMT5_C)
PF00400
(WD40)
3 HIS B 114
SER A 230
ASN B 154
None
0.82A 3s8pB-4g56B:
undetectable
3s8pB-4g56B:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g8t GLUCARATE
DEHYDRATASE


(Actinobacillus
succinogenes)
PF13378
(MR_MLE_C)
3 HIS A 335
SER A 343
ASN A 338
None
None
SO4  A 501 ( 4.9A)
0.90A 3s8pB-4g8tA:
undetectable
3s8pB-4g8tA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gfh DNA TOPOISOMERASE 2

(Saccharomyces
cerevisiae)
PF00204
(DNA_gyraseB)
PF00521
(DNA_topoisoIV)
PF01751
(Toprim)
PF02518
(HATPase_c)
PF16898
(TOPRIM_C)
3 HIS A 316
SER A 379
ASN A 306
None
0.82A 3s8pB-4gfhA:
undetectable
3s8pB-4gfhA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gyp GLUCARATE
DEHYDRATASE-RELATED
PROTEIN


(Escherichia
coli)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
3 HIS C 338
SER C 346
ASN C 341
CIT  C 501 (-3.9A)
None
CIT  C 501 ( 4.8A)
0.88A 3s8pB-4gypC:
undetectable
3s8pB-4gypC:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hb9 SIMILARITIES WITH
PROBABLE
MONOOXYGENASE


(Photorhabdus
laumondii)
PF01494
(FAD_binding_3)
3 HIS A 320
SER A 300
ASN A 370
None
0.75A 3s8pB-4hb9A:
undetectable
3s8pB-4hb9A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hn8 D-GLUCARATE
DEHYDRATASE


(Pseudomonas
mendocina)
PF13378
(MR_MLE_C)
3 HIS A 356
SER A 364
ASN A 359
None
None
GOL  A 502 (-4.2A)
0.90A 3s8pB-4hn8A:
undetectable
3s8pB-4hn8A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hxx METHIONINE
AMINOPEPTIDASE 1


(Homo sapiens)
PF00557
(Peptidase_M24)
3 HIS A 317
SER A 363
ASN A 242
None
0.77A 3s8pB-4hxxA:
undetectable
3s8pB-4hxxA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hyr GLUCARATE
DEHYDRATASE


(Acidaminococcus
intestini)
PF13378
(MR_MLE_C)
3 HIS A 335
SER A 343
ASN A 338
None
0.88A 3s8pB-4hyrA:
undetectable
3s8pB-4hyrA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ina SACCHAROPINE
DEHYDROGENASE


(Wolinella
succinogenes)
PF03435
(Sacchrp_dh_NADP)
PF16653
(Sacchrp_dh_C)
3 HIS A 231
SER A 236
ASN A 108
None
0.71A 3s8pB-4inaA:
undetectable
3s8pB-4inaA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4isy CYSTEINE DESULFURASE

(Mycobacterium
tuberculosis)
PF00266
(Aminotran_5)
3 HIS A 100
SER A 148
ASN A  73
LLP  A 205 ( 3.6A)
None
None
0.84A 3s8pB-4isyA:
undetectable
3s8pB-4isyA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iu6 METHIONINE
AMINOPEPTIDASE 1


(Homo sapiens)
PF00557
(Peptidase_M24)
3 HIS A 317
SER A 363
ASN A 242
None
0.78A 3s8pB-4iu6A:
undetectable
3s8pB-4iu6A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mee DIFFUSE ADHERENCE
ADHESIN


(Escherichia
coli)
PF03797
(Autotransporter)
3 HIS A1271
SER A1240
ASN A1274
None
0.73A 3s8pB-4meeA:
undetectable
3s8pB-4meeA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n9f VIRION INFECTIVITY
FACTOR


(Human
immunodeficiency
virus 1)
no annotation 3 HIS b  80
SER b  52
ASN b  19
None
0.82A 3s8pB-4n9fb:
undetectable
3s8pB-4n9fb:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ou2 2-AMINOMUCONATE
6-SEMIALDEHYDE
DEHYDROGENASE


(Pseudomonas
fluorescens)
PF00171
(Aldedh)
3 HIS A 349
SER A 197
ASN A 297
None
0.83A 3s8pB-4ou2A:
undetectable
3s8pB-4ou2A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rnx NADPH DEHYDROGENASE
1


(Saccharomyces
pastorianus)
PF00724
(Oxidored_FMN)
3 HIS A  54
SER A 384
ASN A 388
None
0.77A 3s8pB-4rnxA:
undetectable
3s8pB-4rnxA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w8j PESTICIDAL CRYSTAL
PROTEIN CRY1AC


(Bacillus
thuringiensis)
PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N)
3 HIS A 319
SER A 363
ASN A 270
None
0.89A 3s8pB-4w8jA:
undetectable
3s8pB-4w8jA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wsq AP2-ASSOCIATED
PROTEIN KINASE 1


(Homo sapiens)
PF00069
(Pkinase)
3 HIS A 287
SER A 340
ASN A 279
None
0.83A 3s8pB-4wsqA:
undetectable
3s8pB-4wsqA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xmv AMINOPEPTIDASE N

(Escherichia
coli)
PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C)
3 HIS A 301
SER A 233
ASN A 269
ZN  A 901 ( 3.2A)
None
None
0.89A 3s8pB-4xmvA:
undetectable
3s8pB-4xmvA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yzw AGAP004976-PA

(Anopheles
gambiae)
PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C)
3 HIS A 223
SER A  97
ASN A 380
CU  A 801 (-3.0A)
None
None
0.91A 3s8pB-4yzwA:
0.0
3s8pB-4yzwA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yzw AGAP004976-PA

(Anopheles
gambiae)
PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C)
3 HIS A 227
SER A  97
ASN A 380
CU  A 801 (-3.2A)
None
None
0.85A 3s8pB-4yzwA:
0.0
3s8pB-4yzwA:
19.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5cpr HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1


(Homo sapiens)
PF00856
(SET)
3 HIS B  98
SER B 205
ASN B 272
SAM  B 402 (-3.7A)
SAM  B 402 (-2.7A)
SAM  B 402 (-3.1A)
0.16A 3s8pB-5cprB:
35.7
3s8pB-5cprB:
97.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dll AMINOPEPTIDASE N

(Francisella
tularensis)
PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C)
3 HIS A 306
SER A 242
ASN A 278
ZN  A 901 (-3.3A)
None
None
0.84A 3s8pB-5dllA:
undetectable
3s8pB-5dllA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fjq CARBOHYDRATE BINDING
PROTEIN, PUTATIVE,
CPB33A


(Cellvibrio
japonicus)
PF03067
(LPMO_10)
3 HIS A 178
SER A  41
ASN A 132
None
0.90A 3s8pB-5fjqA:
undetectable
3s8pB-5fjqA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gp4 GLUTAMATE
DECARBOXYLASE


(Lactobacillus
brevis)
no annotation 3 HIS C 196
SER C 162
ASN C 414
None
0.75A 3s8pB-5gp4C:
undetectable
3s8pB-5gp4C:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gz4 SNAKE VENOM
PHOSPHODIESTERASE
(PDE)


(Naja atra)
PF01033
(Somatomedin_B)
PF01223
(Endonuclease_NS)
PF01663
(Phosphodiest)
3 HIS A 705
SER A 675
ASN A 689
None
0.65A 3s8pB-5gz4A:
undetectable
3s8pB-5gz4A:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ig4 PREDICTED PROTEIN

(Nematostella
vectensis)
PF08332
(CaMKII_AD)
3 HIS A 395
SER A 360
ASN A 464
None
0.80A 3s8pB-5ig4A:
undetectable
3s8pB-5ig4A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ig5 CAMKII-B HUB

(Nematostella
vectensis)
PF08332
(CaMKII_AD)
3 HIS A 395
SER A 360
ASN A 464
None
0.85A 3s8pB-5ig5A:
undetectable
3s8pB-5ig5A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j1k TOXR-ACTIVATED GENE
(TAGE)


(Helicobacter
pylori)
PF01551
(Peptidase_M23)
3 HIS A 218
SER A 239
ASN A 192
None
0.87A 3s8pB-5j1kA:
undetectable
3s8pB-5j1kA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kte DIVALENT METAL
CATION TRANSPORTER
MNTH


(Deinococcus
radiodurans)
PF01566
(Nramp)
3 HIS A 232
SER A 377
ASN A  59
None
0.77A 3s8pB-5kteA:
undetectable
3s8pB-5kteA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lki TCDA1

(Photorhabdus
luminescens)
PF03538
(VRP1)
3 HIS A1128
SER A1014
ASN A1304
None
0.91A 3s8pB-5lkiA:
undetectable
3s8pB-5lkiA:
7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m45 ACETONE CARBOXYLASE
BETA SUBUNIT


(Xanthobacter
autotrophicus)
PF01968
(Hydantoinase_A)
PF05378
(Hydant_A_N)
3 HIS B 184
SER B 215
ASN B  99
None
0.90A 3s8pB-5m45B:
undetectable
3s8pB-5m45B:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m86 TA1207

(Thermoplasma
acidophilum)
no annotation 3 HIS A 245
SER A 108
ASN A 157
None
0.82A 3s8pB-5m86A:
undetectable
3s8pB-5m86A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m95 DIVALENT METAL
CATION TRANSPORTER
MNTH


(Staphylococcus
capitis)
PF01566
(Nramp)
3 HIS A 228
SER A 388
ASN A  52
None
None
MN  A 501 (-3.0A)
0.81A 3s8pB-5m95A:
undetectable
3s8pB-5m95A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5msx PUTATIVE
ENDO-1,4-BETA-XYLANA
SE


(Bacteroides
thetaiotaomicron)
PF00754
(F5_F8_type_C)
PF04616
(Glyco_hydro_43)
3 HIS A  76
SER A 430
ASN A 364
None
0.80A 3s8pB-5msxA:
undetectable
3s8pB-5msxA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n4l CERULOPLASMIN

(Rattus
norvegicus)
no annotation 3 HIS A 596
SER A 623
ASN A 626
None
0.70A 3s8pB-5n4lA:
undetectable
3s8pB-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oik TRANSCRIPTION
ELONGATION FACTOR
SPT4
TRANSCRIPTION
ELONGATION FACTOR
SPT5


(Homo sapiens;
Homo sapiens)
PF06093
(Spt4)
PF00467
(KOW)
PF03439
(Spt5-NGN)
3 HIS Y  12
SER Y  56
ASN Z 301
None
0.80A 3s8pB-5oikY:
undetectable
3s8pB-5oikY:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ojs TRANSCRIPTION-ASSOCI
ATED PROTEIN 1


(Saccharomyces
cerevisiae)
PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
3 HIS T2091
SER T2005
ASN T  39
None
0.90A 3s8pB-5ojsT:
undetectable
3s8pB-5ojsT:
5.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5olk RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT 1


(Leeuwenhoekiella
blandensis)
no annotation 3 HIS A 209
SER A 167
ASN A 217
None
0.69A 3s8pB-5olkA:
undetectable
3s8pB-5olkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t9g GLYCOSIDE HYDROLASE

(Bacteroides
uniformis)
PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF16355
(DUF4982)
3 HIS A 798
SER A 325
ASN A 795
None
0.89A 3s8pB-5t9gA:
undetectable
3s8pB-5t9gA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE


(Vibrio cholerae)
PF00768
(Peptidase_S11)
PF07943
(PBP5_C)
3 HIS A 165
SER A  63
ASN A 168
None
0.89A 3s8pB-5tr7A:
undetectable
3s8pB-5tr7A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u1s SEPARIN

(Saccharomyces
cerevisiae)
PF03568
(Peptidase_C50)
3 HIS A 186
SER A 192
ASN A 269
None
0.88A 3s8pB-5u1sA:
2.5
3s8pB-5u1sA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y6t ENDO-1,4-BETA-MANNAN
ASE


(Eisenia fetida)
no annotation 3 HIS A 278
SER A 290
ASN A 305
None
0.87A 3s8pB-5y6tA:
undetectable
3s8pB-5y6tA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE


(Plasmodium
vivax)
no annotation 3 HIS A 397
SER A 431
ASN A 425
None
0.79A 3s8pB-6bpcA:
undetectable
3s8pB-6bpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6brk DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1


(Mus musculus)
no annotation 3 HIS A 391
SER A 394
ASN A 338
None
0.89A 3s8pB-6brkA:
undetectable
3s8pB-6brkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bv2 AMINOPEPTIDASE N

(Sus scrofa)
no annotation 3 HIS A 786
SER A 791
ASN A 373
None
0.85A 3s8pB-6bv2A:
undetectable
3s8pB-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE


(Bacillus
subtilis)
no annotation 3 HIS A 313
SER A 374
ASN A 202
None
0.76A 3s8pB-6cgmA:
undetectable
3s8pB-6cgmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoj PROTEIN CFT1
POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2


(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae)
no annotation
no annotation
3 HIS D  48
SER A1173
ASN A1016
None
0.87A 3s8pB-6eojD:
undetectable
3s8pB-6eojD:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fa5 PUTATIVE MRNA
SPLICING FACTOR


(Chaetomium
thermophilum)
no annotation 3 HIS A 335
SER A 413
ASN A 343
None
0.91A 3s8pB-6fa5A:
1.0
3s8pB-6fa5A:
undetectable