SIMILAR PATTERNS OF AMINO ACIDS FOR 3S8P_B_SAMB500_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ex0 | COAGULATION FACTORXIII A CHAIN (Homo sapiens) |
PF00868(Transglut_N)PF00927(Transglut_C)PF01841(Transglut_core) | 5 | GLY A 410ALA A 412PHE A 430CYH A 314CYH A 374 | None | 1.18A | 3s8pB-1ex0A:0.0 | 3s8pB-1ex0A:16.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jqk | CARBON MONOXIDEDEHYDROGENASE (Rhodospirillumrubrum) |
PF03063(Prismane) | 5 | GLY A 623ALA A 622SER A 460TYR A 462PHE A 486 | None | 1.23A | 3s8pB-1jqkA:undetectable | 3s8pB-1jqkA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lsh | LIPOVITELLIN (LV-1N,LV-1C) (Ichthyomyzonunicuspis) |
PF01347(Vitellogenin_N)PF09172(DUF1943) | 5 | GLY A 481ALA A 479HIS A 746TYR A 194GLU A 675 | NoneNonePLD A2007 ( 3.9A)PLD A2005 (-4.4A)None | 1.43A | 3s8pB-1lshA:0.0 | 3s8pB-1lshA:12.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rvk | ISOMERASE/LACTONIZING ENZYME (Agrobacteriumfabrum) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | TYR A 153GLY A 154ALA A 192HIS A 171CYH A 139 | None | 1.48A | 3s8pB-1rvkA:undetectable | 3s8pB-1rvkA:18.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vb3 | THREONINE SYNTHASE (Escherichiacoli) |
PF00291(PALP)PF14821(Thr_synth_N) | 5 | GLY A 256ALA A 255SER A 55PHE A 38GLU A 37 | None | 1.12A | 3s8pB-1vb3A:0.4 | 3s8pB-1vb3A:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a8x | DIHYDROLIPOYLDEHYDROGENASE (Mycobacteriumtuberculosis) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | GLU A 201GLY A 178ALA A 177PHE A 202GLU A 219 | None | 1.43A | 3s8pB-2a8xA:0.1 | 3s8pB-2a8xA:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cb9 | FENGYCIN SYNTHETASE (Bacillussubtilis) |
PF00975(Thioesterase) | 5 | GLY A 199ALA A 200SER A 84TYR A 113PHE A 166 | NoneNoneACY A1225 (-2.5A)NoneNone | 0.99A | 3s8pB-2cb9A:undetectable | 3s8pB-2cb9A:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nnj | CYTOCHROME P450 2C8 (Homo sapiens) |
PF00067(p450) | 5 | TYR A 80GLY A 79ALA A 82SER A 429GLU A 400 | NoneNoneNoneHEM A 500 (-2.9A)None | 1.42A | 3s8pB-2nnjA:2.2 | 3s8pB-2nnjA:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rgj | FLAVIN-CONTAININGMONOOXYGENASE (Pseudomonasaeruginosa) |
PF01494(FAD_binding_3) | 5 | GLY A 63ALA A 58SER A 18HIS A 24GLU A 119 | None | 1.31A | 3s8pB-2rgjA:0.0 | 3s8pB-2rgjA:18.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vqd | BIOTIN CARBOXYLASE (Pseudomonasaeruginosa) |
PF00289(Biotin_carb_N)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 5 | GLY A 163ALA A 160SER A 118PHE A 286GLU A 276 | NoneNoneNoneNone MG A1449 ( 2.7A) | 1.41A | 3s8pB-2vqdA:undetectable | 3s8pB-2vqdA:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zbl | PUTATIVE ISOMERASE (Salmonellaenterica) |
PF07221(GlcNAc_2-epim) | 5 | GLY A 406ALA A 405SER A 61PHE A 21GLU A 14 | None | 1.47A | 3s8pB-2zblA:undetectable | 3s8pB-2zblA:18.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e3m | TRANSCRIPTIONALREGULATOR, LACIFAMILY (Ruegeriapomeroyi) |
PF13377(Peripla_BP_3) | 5 | GLY A 226ALA A 227SER A 256PHE A 190GLU A 222 | None | 1.26A | 3s8pB-3e3mA:undetectable | 3s8pB-3e3mA:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f7c | PROTEIN OF UNKNOWNFUNCTION (DUF416) (Marinobacterhydrocarbonoclasticus) |
PF04222(DUF416) | 5 | TYR A 91GLY A 89ALA A 87PHE A 129SER A 133 | None | 1.38A | 3s8pB-3f7cA:undetectable | 3s8pB-3f7cA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fqd | 5'-3'EXORIBONUCLEASE 2 (Schizosaccharomycespombe) |
PF03159(XRN_N) | 5 | TYR A 639GLY A 620PHE A 337HIS A 642PHE A 726 | None | 1.47A | 3s8pB-3fqdA:0.1 | 3s8pB-3fqdA:15.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gsi | N,N-DIMETHYLGLYCINEOXIDASE (Arthrobacterglobiformis) |
PF01266(DAO)PF01571(GCV_T)PF08669(GCV_T_C)PF16350(FAO_M) | 5 | GLU A 358GLY A 207ALA A 208SER A 348CYH A 388 | None | 1.42A | 3s8pB-3gsiA:undetectable | 3s8pB-3gsiA:14.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k1d | 1,4-ALPHA-GLUCAN-BRANCHING ENZYME (Mycobacteriumtuberculosis) |
PF00128(Alpha-amylase)PF02806(Alpha-amylase_C)PF02922(CBM_48) | 5 | GLY A 131ALA A 132SER A 310PHE A 403GLU A 402 | None | 1.43A | 3s8pB-3k1dA:undetectable | 3s8pB-3k1dA:15.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l01 | GLGA GLYCOGENSYNTHASE (Pyrococcusabyssi) |
PF00534(Glycos_transf_1)PF08323(Glyco_transf_5) | 5 | GLY A 342ALA A 345PHE A 412SER A 411GLU A 20 | K A5600 (-4.4A)NoneNoneNoneNone | 1.32A | 3s8pB-3l01A:undetectable | 3s8pB-3l01A:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n71 | HISTONE LYSINEMETHYLTRANSFERASESMYD1 (Mus musculus) |
PF00856(SET)PF01753(zf-MYND) | 5 | HIS A 206TYR A 252PHE A 272CYH A 274CYH A 276 | NoneSFG A 491 (-4.8A)SFG A 491 (-3.7A) ZN A 497 (-2.2A) ZN A 497 (-2.5A) | 1.09A | 3s8pB-3n71A:7.1 | 3s8pB-3n71A:19.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nqi | PUTATIVE LIPOPROTEIN (Bacteroidesfragilis) |
no annotation | 5 | GLY A 100PHE A 212HIS A 169TYR A 151PHE A 171 | NonePEG A 329 (-4.8A)NoneNoneNone | 1.35A | 3s8pB-3nqiA:undetectable | 3s8pB-3nqiA:19.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nqi | PUTATIVE LIPOPROTEIN (Bacteroidesfragilis) |
no annotation | 5 | GLY A 100SER A 210HIS A 169TYR A 151PHE A 171 | NonePEG A 329 (-3.6A)NoneNoneNone | 1.45A | 3s8pB-3nqiA:undetectable | 3s8pB-3nqiA:19.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pie | 5'->3'EXORIBONUCLEASE(XRN1) (Kluyveromyceslactis) |
PF03159(XRN_N) | 5 | TYR A 559GLY A 540PHE A 292HIS A 562PHE A 646 | None | 1.41A | 3s8pB-3pieA:undetectable | 3s8pB-3pieA:12.89 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4au7 | HISTONE-LYSINEN-METHYLTRANSFERASESUV420H2 (Mus musculus) |
PF00856(SET) | 11 | TYR A 114GLU A 117GLY A 120ALA A 121PHE A 160HIS A 183TYR A 217PHE A 222CYH A 229GLU A 230CYH A 231 | SAH A1247 ( 3.6A)SAH A1247 (-2.8A)SAH A1247 (-3.2A)SAH A1247 (-4.1A)NoneSAH A1247 (-4.6A)NoneSAH A1247 (-4.0A) ZN A1248 ( 2.3A)EDO A1251 ( 2.8A) ZN A1248 ( 2.2A) | 0.36A | 3s8pB-4au7A:8.5 | 3s8pB-4au7A:60.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4au7 | HISTONE-LYSINEN-METHYLTRANSFERASESUV420H2 (Mus musculus) |
PF00856(SET) | 11 | TYR A 114GLU A 117GLY A 120ALA A 121SER A 161HIS A 183TYR A 217PHE A 222CYH A 229GLU A 230CYH A 231 | SAH A1247 ( 3.6A)SAH A1247 (-2.8A)SAH A1247 (-3.2A)SAH A1247 (-4.1A)NoneSAH A1247 (-4.6A)NoneSAH A1247 (-4.0A) ZN A1248 ( 2.3A)EDO A1251 ( 2.8A) ZN A1248 ( 2.2A) | 0.66A | 3s8pB-4au7A:8.5 | 3s8pB-4au7A:60.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4au7 | HISTONE-LYSINEN-METHYLTRANSFERASESUV420H2 (Mus musculus) |
PF00856(SET) | 8 | TYR A 114GLU A 117GLY A 120PHE A 160HIS A 183TYR A 217GLU A 230CYH A 229 | SAH A1247 ( 3.6A)SAH A1247 (-2.8A)SAH A1247 (-3.2A)NoneSAH A1247 (-4.6A)NoneEDO A1251 ( 2.8A) ZN A1248 ( 2.3A) | 1.48A | 3s8pB-4au7A:8.5 | 3s8pB-4au7A:60.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b92 | DIHYDROPYRIMIDINASE-RELATED PROTEIN 5 (Homo sapiens) |
PF01979(Amidohydro_1) | 5 | TYR A 83GLY A 85ALA A 88SER A 441GLU A 456 | None | 1.41A | 3s8pB-4b92A:undetectable | 3s8pB-4b92A:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gkv | ALCOHOLDEHYDROGENASE,PROPANOL-PREFERRING (Escherichiacoli) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | GLY A 62ALA A 80HIS A 58CYH A 37CYH A 145 | NoneNone ZN A 402 (-3.3A) ZN A 402 ( 2.4A) ZN A 402 ( 2.3A) | 1.45A | 3s8pB-4gkvA:undetectable | 3s8pB-4gkvA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l37 | SILKWORM STORAGEPROTEIN (Bombyx mori) |
PF00372(Hemocyanin_M)PF03722(Hemocyanin_N)PF03723(Hemocyanin_C) | 5 | TYR A 235GLY A 233HIS A 225PHE A 622GLU A 620 | None | 1.27A | 3s8pB-4l37A:undetectable | 3s8pB-4l37A:16.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lfe | GERANYLGERANYLDIPHOSPHATE SYNTHASE (Streptococcusuberis) |
PF00348(polyprenyl_synt) | 5 | GLY A 117ALA A 115HIS A 12GLU A 17CYH A 16 | None | 1.41A | 3s8pB-4lfeA:2.3 | 3s8pB-4lfeA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p5i | CHEMOKINE BINDINGPROTEIN (Orf virus) |
PF02250(Orthopox_35kD) | 5 | GLY A 269SER A 125HIS A 21PHE A 17GLU A 13 | None | 1.21A | 3s8pB-4p5iA:undetectable | 3s8pB-4p5iA:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w6z | ALCOHOLDEHYDROGENASE 1 (Saccharomycescerevisiae) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | GLY A 70ALA A 88HIS A 66CYH A 43CYH A 153 | NoneNone ZN A 401 ( 3.1A) ZN A 401 (-2.2A) ZN A 401 (-2.3A) | 1.36A | 3s8pB-4w6zA:undetectable | 3s8pB-4w6zA:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zo6 | LIN1840 PROTEIN (Listeriainnocua) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 5 | GLY A 58ALA A 57PHE A 88SER A 63PHE A 135 | NoneNoneNoneNoneBGC A 802 (-4.3A) | 1.05A | 3s8pB-4zo6A:undetectable | 3s8pB-4zo6A:16.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a6f | GATING RING OFPOTASSIUM CHANNELSUBFAMILY T MEMBER 1 (Gallus gallus) |
PF03493(BK_channel_a) | 5 | TYR C 788GLY C 786PHE C 790PHE C 826CYH C 825 | None | 1.45A | 3s8pB-5a6fC:undetectable | 3s8pB-5a6fC:17.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b3h | PROTEIN SHORT-ROOT (Arabidopsisthaliana) |
PF03514(GRAS) | 5 | TYR B 203GLU B 200GLY B 199ALA B 452SER B 456 | None | 1.39A | 3s8pB-5b3hB:undetectable | 3s8pB-5b3hB:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5by3 | BTGH115A (Bacteroidesthetaiotaomicron) |
PF15979(Glyco_hydro_115) | 5 | TYR A 211GLY A 164ALA A 208PHE A 238PHE A 222 | None | 1.36A | 3s8pB-5by3A:undetectable | 3s8pB-5by3A:15.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5cpr | HISTONE-LYSINEN-METHYLTRANSFERASESUV420H1 (Homo sapiens) |
PF00856(SET) | 11 | TYR B 203GLU B 206GLY B 209ALA B 210PHE B 250HIS B 273TYR B 307PHE B 312CYH B 319GLU B 320CYH B 321 | SAM B 402 (-3.7A)SAM B 402 (-2.9A)SAM B 402 (-3.4A)SAM B 402 (-3.9A)NoneSAM B 402 (-4.5A)539 B 403 ( 3.9A)SAM B 402 (-3.7A) ZN B 401 ( 2.3A)SAM B 402 (-4.6A) ZN B 401 ( 2.2A) | 0.26A | 3s8pB-5cprB:35.7 | 3s8pB-5cprB:97.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5cpr | HISTONE-LYSINEN-METHYLTRANSFERASESUV420H1 (Homo sapiens) |
PF00856(SET) | 11 | TYR B 203GLU B 206GLY B 209ALA B 210SER B 251HIS B 273TYR B 307PHE B 312CYH B 319GLU B 320CYH B 321 | SAM B 402 (-3.7A)SAM B 402 (-2.9A)SAM B 402 (-3.4A)SAM B 402 (-3.9A)SAM B 402 (-3.9A)SAM B 402 (-4.5A)539 B 403 ( 3.9A)SAM B 402 (-3.7A) ZN B 401 ( 2.3A)SAM B 402 (-4.6A) ZN B 401 ( 2.2A) | 0.46A | 3s8pB-5cprB:35.7 | 3s8pB-5cprB:97.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5cpr | HISTONE-LYSINEN-METHYLTRANSFERASESUV420H1 (Homo sapiens) |
PF00856(SET) | 8 | TYR B 203GLU B 206GLY B 209PHE B 250HIS B 273TYR B 307GLU B 320CYH B 319 | SAM B 402 (-3.7A)SAM B 402 (-2.9A)SAM B 402 (-3.4A)NoneSAM B 402 (-4.5A)539 B 403 ( 3.9A)SAM B 402 (-4.6A) ZN B 401 ( 2.3A) | 1.41A | 3s8pB-5cprB:35.7 | 3s8pB-5cprB:97.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gnw | BLR0248 PROTEIN (Bradyrhizobiumdiazoefficiens) |
no annotation | 5 | TYR C 118GLY C 114ALA C 26PHE C 96CYH C 18 | None | 1.23A | 3s8pB-5gnwC:undetectable | 3s8pB-5gnwC:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gvx | TREHALOSE-PHOSPHATEPHOSPHATASE (Mycobacteriumtuberculosis) |
PF02358(Trehalose_PPase) | 5 | TYR A 261GLY A 270PHE A 245HIS A 260GLU A 292 | None | 1.31A | 3s8pB-5gvxA:undetectable | 3s8pB-5gvxA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5odr | METHYL-VIOLOGENREDUCINGHYDROGENASE, SUBUNITGMETHYL-VIOLOGENREDUCINGHYDROGENASE, SUBUNITA (Methanothermococcusthermolithotrophicus;Methanothermococcusthermolithotrophicus) |
PF01058(Oxidored_q6)PF00374(NiFeSe_Hases) | 5 | GLU E 57GLY E 58SER E 18CYH F 442CYH F 445 | SF4 E 302 (-3.8A)SF4 E 302 ( 4.9A)NoneNFU F 501 (-2.2A)NFU F 501 (-2.4A) | 1.28A | 3s8pB-5odrE:undetectable | 3s8pB-5odrE:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5te4 | HIV-1 CLADE G STRAINX2088 GP120 (Humanimmunodeficiencyvirus 1) |
PF00516(GP120) | 5 | GLY G 366ALA G 365SER G 388HIS G 374GLU G 370 | NoneNoneNAG G 508 (-3.3A)NoneNone | 1.46A | 3s8pB-5te4G:undetectable | 3s8pB-5te4G:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tuy | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT2 (Homo sapiens) |
PF00856(SET)PF05033(Pre-SET) | 5 | SER A1084HIS A1113TYR A1154CYH A1168CYH A1170 | SAM A1505 (-3.8A)SAM A1505 (-4.7A)SAM A1505 (-4.9A) ZN A1504 (-2.2A) ZN A1504 (-2.2A) | 1.38A | 3s8pB-5tuyA:7.3 | 3s8pB-5tuyA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xfa | NAD-REDUCINGHYDROGENASENAD-REDUCINGHYDROGENASE (Hydrogenophilusthermoluteolus;Hydrogenophilusthermoluteolus) |
PF01058(Oxidored_q6)PF00374(NiFeSe_Hases) | 5 | GLU C 67GLY C 68SER C 30CYH D 462CYH D 465 | SF4 C 201 ( 3.6A)SF4 C 201 ( 4.5A)None NI D 502 ( 2.3A)FCO D 501 ( 2.3A) | 1.20A | 3s8pB-5xfaC:undetectable | 3s8pB-5xfaC:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f5o | POLYMERASE ACIDICPROTEINRNA-DIRECTED RNAPOLYMERASE CATALYTICSUBUNIT (Influenza Bvirus;Influenza Bvirus) |
no annotationno annotation | 5 | GLU A 585GLY B 539SER A 580PHE A 629CYH A 603 | None | 1.46A | 3s8pB-6f5oA:undetectable | 3s8pB-6f5oA:undetectable |