SIMILAR PATTERNS OF AMINO ACIDS FOR 3RZE_A_D7VA1201

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1em2 MLN64 PROTEIN

(Homo sapiens) 		PF01852
(START) 		5 THR A 282
ILE A 405
ASN A 407
TRP A 404
PHE A 347
 None
 1.40A 3rzeA-1em2A:
undetectable		 3rzeA-1em2A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yj8 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE

(Plasmodium
falciparum) 		PF01210
(NAD_Gly3P_dh_N)
PF07479
(NAD_Gly3P_dh_C) 		5 ASP A 281
SER A 170
THR A 187
ILE A 188
PHE A 208
 None
 1.37A 3rzeA-1yj8A:
undetectable		 3rzeA-1yj8A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yvp 60-KDA SS-A/RO
RIBONUCLEOPROTEIN

(Xenopus laevis) 		PF05731
(TROVE) 		5 ASP A 376
SER A 378
THR A 441
ASN A 382
TYR A  47
 MG  A1001 ( 4.5A)
MG  A1001 ( 2.2A)
None
None
None
 1.49A 3rzeA-1yvpA:
undetectable		 3rzeA-1yvpA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jty TYPE-1 FIMBRIAL
PROTEIN, A CHAIN

(Escherichia
coli) 		PF00419
(Fimbrial) 		5 THR A 130
ASN A  55
PHE A 133
PHE A  73
TYR A 158
 None
 1.48A 3rzeA-2jtyA:
undetectable		 3rzeA-2jtyA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nym SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
CATALYTIC SUBUNIT
ALPHA ISOFORM

(Homo sapiens) 		PF00149
(Metallophos) 		5 ASP C 131
TYR C 130
THR C 124
ILE C 123
TRP C 143
 None
 0.93A 3rzeA-2nymC:
undetectable		 3rzeA-2nymC:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pkd SLAM FAMILY MEMBER 5

(Homo sapiens) 		no annotation 5 ASP A  96
TYR A  98
THR A  99
ILE A  91
ASN A  92
 None
 1.27A 3rzeA-2pkdA:
undetectable		 3rzeA-2pkdA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vr5 GLYCOGEN OPERON
PROTEIN GLGX

(Sulfolobus
solfataricus) 		PF00128
(Alpha-amylase)
PF02806
(Alpha-amylase_C)
PF02922
(CBM_48) 		5 TYR A 109
ILE A 106
ASN A 248
TYR A 312
PHE A 304
 None
 1.08A 3rzeA-2vr5A:
undetectable		 3rzeA-2vr5A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ecd SERINE
HYDROXYMETHYLTRANSFE
RASE 2

(Burkholderia
pseudomallei) 		PF00464
(SHMT) 		5 ASP A 325
SER A 363
THR A 362
ILE A 361
PHE A 393
 None
 1.29A 3rzeA-3ecdA:
undetectable		 3rzeA-3ecdA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o66 GLYCINE
BETAINE/CARNITINE/CH
OLINE ABC
TRANSPORTER

(Staphylococcus
aureus) 		PF04069
(OpuAC) 		5 ASP A  98
SER A  75
THR A  76
ILE A  77
ASN A  80
 None
 1.12A 3rzeA-3o66A:
undetectable		 3rzeA-3o66A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3om5 LEVANSUCRASE

(Bacillus
megaterium) 		PF02435
(Glyco_hydro_68) 		5 THR A 333
ILE A 227
TYR A 260
PHE A 187
TYR A 268
 None
 1.31A 3rzeA-3om5A:
undetectable		 3rzeA-3om5A:
21.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA

(Escherichia
virus T4;
Homo sapiens) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		6 ASP A 110
THR A 115
ILE A 118
TRP A 342
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
None
None
None
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.53A 3rzeA-3pblA:
36.3		 3rzeA-3pblA:
54.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME

(Escherichia
virus T4;
Homo sapiens) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		6 ASP A 113
THR A 118
ILE A 121
TRP A 286
PHE A 290
TYR A 316
 ERC  A1201 (-3.7A)
None
None
None
ERC  A1201 (-4.8A)
None
 0.58A 3rzeA-3pdsA:
36.2		 3rzeA-3pdsA:
55.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN

(Escherichia
virus T4;
Homo sapiens) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		5 ASP A 103
TYR A 104
SER A 107
TRP A 155
TRP A 400
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.2A)
QNB  A1162 (-4.7A)
 1.13A 3rzeA-3uonA:
34.4		 3rzeA-3uonA:
58.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3uon HUMAN M2 MUSCARINIC
ACETYLCHOLINE,
RECEPTOR T4 LYSOZYME
FUSION PROTEIN

(Escherichia
virus T4;
Homo sapiens) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		6 ASP A 103
TYR A 104
SER A 107
TRP A 155
TYR A 403
TYR A 430
 QNB  A1162 (-3.1A)
QNB  A1162 (-4.0A)
QNB  A1162 (-3.4A)
QNB  A1162 (-4.2A)
QNB  A1162 (-3.9A)
QNB  A1162 ( 4.8A)
 0.79A 3rzeA-3uonA:
34.4		 3rzeA-3uonA:
58.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d1i BETA-GALACTOSIDASE,
PUTATIVE, BGL35A

(Cellvibrio
japonicus) 		PF02449
(Glyco_hydro_42) 		5 THR A 395
ILE A 396
ASN A 352
PHE A 371
TYR A 509
 None
 1.35A 3rzeA-4d1iA:
undetectable		 3rzeA-4d1iA:
19.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4dkl MU-TYPE OPIOID
RECEPTOR, LYSOZYME
CHIMERA

(Escherichia
virus T4;
Mus musculus) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		5 ASP A 147
TYR A 148
ILE A 155
TRP A 293
TYR A 326
 BF0  A 601 (-3.2A)
BF0  A 601 (-4.0A)
None
BF0  A 601 (-4.8A)
BF0  A 601 (-3.8A)
 0.78A 3rzeA-4dklA:
28.8		 3rzeA-4dklA:
53.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dsh UDP-GALACTOPYRANOSE
MUTASE

(Trypanosoma
cruzi) 		PF01593
(Amino_oxidase)
PF13450
(NAD_binding_8) 		5 THR A 245
ILE A 239
TYR A  36
PHE A 248
PHE A 234
 None
 1.46A 3rzeA-4dshA:
undetectable		 3rzeA-4dshA:
20.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ej4 DELTA-TYPE OPIOID
RECEPTOR, LYSOZYME
CHIMERA

(Escherichia
virus T4;
Mus musculus) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		5 ASP A 128
TYR A 129
ILE A 136
TRP A 274
TYR A 308
 EJ4  A 500 (-3.0A)
EJ4  A 500 (-4.4A)
None
EJ4  A 500 (-4.5A)
EJ4  A 500 (-3.8A)
 0.81A 3rzeA-4ej4A:
32.7		 3rzeA-4ej4A:
52.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gbr BETA-2 ADRENERGIC
RECEPTOR

(Homo sapiens) 		PF00001
(7tm_1) 		6 ASP A 113
THR A 118
ILE A 121
TRP A 258
PHE A 262
TYR A 288
 CAU  A 500 (-3.0A)
CAU  A 500 ( 4.7A)
None
None
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 0.73A 3rzeA-4gbrA:
31.0		 3rzeA-4gbrA:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562

(Escherichia
coli;
Homo sapiens) 		PF00001
(7tm_1)
PF07361
(Cytochrom_B562) 		6 ASP A 135
SER A 139
THR A 140
ILE A 143
PHE A 341
TYR A 370
 ERM  A2001 (-3.2A)
ERM  A2001 (-3.6A)
ERM  A2001 (-3.9A)
None
None
ERM  A2001 ( 4.8A)
 0.75A 3rzeA-4ib4A:
26.7		 3rzeA-4ib4A:
27.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562

(Escherichia
coli;
Homo sapiens) 		PF00001
(7tm_1)
PF07361
(Cytochrom_B562) 		6 ASP A 135
SER A 139
THR A 140
TRP A 337
PHE A 341
TYR A 370
 ERM  A2001 (-3.2A)
ERM  A2001 (-3.6A)
ERM  A2001 (-3.9A)
None
None
ERM  A2001 ( 4.8A)
 0.69A 3rzeA-4ib4A:
26.7		 3rzeA-4ib4A:
27.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kca ENDO-1,5-ALPHA-L-ARA
BINANASE

(Bos taurus) 		PF00085
(Thioredoxin)
PF04616
(Glyco_hydro_43)
PF16369
(GH43_C) 		5 ASP A 308
SER A 235
ILE A 236
TRP A 217
ASN A 215
 GOL  A 734 (-2.6A)
None
None
GOL  A 734 (-3.7A)
None
 1.48A 3rzeA-4kcaA:
undetectable		 3rzeA-4kcaA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kl0 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Xanthomonas
oryzae) 		PF01156
(IU_nuc_hydro) 		5 THR A 126
ILE A 129
TYR A 320
PHE A 319
TYR A 333
 None
 1.14A 3rzeA-4kl0A:
undetectable		 3rzeA-4kl0A:
21.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR

(Escherichia
virus T4;
Homo sapiens) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		5 ASP A1113
THR A1118
TRP A1286
PHE A1290
TYR A1316
 P0G  A1401 (-2.9A)
None
None
P0G  A1401 ( 4.9A)
None
 0.64A 3rzeA-4ldeA:
27.6		 3rzeA-4ldeA:
36.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2

(Homo sapiens) 		PF00001
(7tm_1) 		5 ASP A 103
TYR A 104
SER A 107
TRP A 155
TRP A 400
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.6A)
IXO  A 501 (-4.6A)
 1.08A 3rzeA-4mqtA:
29.4		 3rzeA-4mqtA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mqt MUSCARINIC
ACETYLCHOLINE
RECEPTOR M2

(Homo sapiens) 		PF00001
(7tm_1) 		5 ASP A 103
TYR A 104
SER A 107
TRP A 155
TYR A 430
 IXO  A 501 (-3.4A)
IXO  A 501 (-3.7A)
IXO  A 501 (-3.4A)
IXO  A 501 (-3.6A)
IXO  A 501 (-4.5A)
 0.81A 3rzeA-4mqtA:
29.4		 3rzeA-4mqtA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nt4 GILGAMESH, ISOFORM I

(Drosophila
melanogaster) 		PF00069
(Pkinase) 		5 ILE A 135
ASN A 134
TRP A 332
PHE A 140
PHE A 248
 None
 1.29A 3rzeA-4nt4A:
undetectable		 3rzeA-4nt4A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rwa SOLUBLE CYTOCHROME
B562,DELTA-TYPE
OPIOID RECEPTOR

(Escherichia
coli;
Homo sapiens) 		PF00001
(7tm_1)
PF07361
(Cytochrom_B562) 		5 ASP A 128
TYR A 129
ILE A 136
TRP A 274
TYR A 308
 None
 0.62A 3rzeA-4rwaA:
27.8		 3rzeA-4rwaA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tz0 ATP-DEPENDENT RNA
HELICASE MSS116,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		5 SER A 536
ILE A 555
TYR A 544
PHE A 546
PHE A 487
 A  B   2 ( 4.2A)
None
None
None
None
 1.43A 3rzeA-4tz0A:
undetectable		 3rzeA-4tz0A:
20.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1

(Escherichia
virus T4;
Homo sapiens) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		5 ASP A 105
TYR A 106
SER A 109
TRP A 157
TRP A 378
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-3.1A)
0HK  A 501 (-4.0A)
0HK  A 501 (-4.4A)
 1.24A 3rzeA-5cxvA:
35.4		 3rzeA-5cxvA:
55.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5cxv MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1

(Escherichia
virus T4;
Homo sapiens) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		5 ASP A 105
TYR A 106
SER A 109
TRP A 157
TYR A 408
 0HK  A 501 (-3.0A)
0HK  A 501 (-3.4A)
0HK  A 501 (-3.1A)
0HK  A 501 (-4.0A)
0HK  A 501 (-4.7A)
 0.77A 3rzeA-5cxvA:
35.4		 3rzeA-5cxvA:
55.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dsg MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4

(Escherichia
virus T4;
Homo sapiens) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		5 ASP A 112
TYR A 113
SER A 116
TRP A 164
TYR A 443
 0HK  A1201 (-4.0A)
0HK  A1201 ( 3.2A)
0HK  A1201 (-3.3A)
OLC  A1208 ( 4.0A)
0HK  A1201 (-4.5A)
 0.90A 3rzeA-5dsgA:
31.2		 3rzeA-5dsgA:
48.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f8u BETA-1 ADRENERGIC
RECEPTOR

(Meleagris
gallopavo) 		no annotation 6 ASP B 121
THR B 126
ILE B 129
TRP B 303
PHE B 307
TYR B 333
 P32  B 400 (-2.2A)
None
None
None
P32  B 400 (-4.9A)
P32  B 400 (-4.6A)
 0.70A 3rzeA-5f8uB:
31.1		 3rzeA-5f8uB:
26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i8o HMM5 ANTIBODY HEAVY
CHAIN
HMM5 ANTIBODY LIGHT
CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		5 ASP H  98
SER H 102
THR H 103
ASN H 104
TYR L  34
 2F8  H 302 (-4.2A)
None
None
None
None
 1.07A 3rzeA-5i8oH:
undetectable		 3rzeA-5i8oH:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jz7 MEDI578 SCFV, HEAVY
CHAIN

(Homo sapiens) 		PF07686
(V-set) 		5 ASP C 100
SER C  95
ILE C  34
TRP C 103
TYR C  99
 None
 1.50A 3rzeA-5jz7C:
undetectable		 3rzeA-5jz7C:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B

(Homo sapiens;
Spodoptera
frugiperda) 		no annotation 6 ASP A 129
THR A 134
ILE A 137
TRP A 327
PHE A 331
TYR A 359
 89F  A1201 (-3.3A)
89F  A1201 (-4.2A)
None
89F  A1201 (-3.6A)
89F  A1201 (-4.6A)
None
 0.64A 3rzeA-5v54A:
28.3		 3rzeA-5v54A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wiv D(4) DOPAMINE
RECEPTOR, SOLUBLE
CYTOCHROME B562
CHIMERA

(Escherichia
coli;
Homo sapiens) 		no annotation 6 ASP A 115
THR A 120
ILE A 123
TRP A 407
PHE A 411
TYR A 438
 AQD  A1201 (-3.3A)
AQD  A1201 (-4.4A)
None
None
AQD  A1201 (-4.6A)
None
 0.66A 3rzeA-5wivA:
28.4		 3rzeA-5wivA:
28.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bqh 5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562

(Escherichia
coli;
Homo sapiens) 		no annotation 7 ASP A 134
SER A 138
THR A 139
ILE A 142
TRP A 324
PHE A 328
TYR A 358
 E2J  A1201 (-3.0A)
E2J  A1201 (-3.2A)
E2J  A1201 (-4.3A)
E2J  A1201 (-3.5A)
E2J  A1201 ( 3.7A)
E2J  A1201 (-4.4A)
None
 0.49A 3rzeA-6bqhA:
28.9		 3rzeA-6bqhA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cm4 D(2) DOPAMINE
RECEPTOR, ENDOLYSIN
CHIMERA

(Escherichia
virus T4;
Homo sapiens) 		no annotation 5 ASP A 114
THR A 119
TRP A 386
PHE A 390
TYR A 416
 8NU  A2001 ( 3.0A)
8NU  A2001 ( 4.4A)
8NU  A2001 ( 3.8A)
8NU  A2001 ( 4.8A)
8NU  A2001 ( 4.9A)
 0.56A 3rzeA-6cm4A:
37.3		 3rzeA-6cm4A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g79 5-HYDROXYTRYPTAMINE
RECEPTOR 1B

(Homo sapiens) 		no annotation 5 ASP S 129
THR S 134
TRP S 327
PHE S 331
TYR S 359
 EP5  S 401 (-3.3A)
EP5  S 401 (-3.8A)
None
EP5  S 401 (-4.7A)
EP5  S 401 ( 4.9A)
 0.83A 3rzeA-6g79S:
28.0		 3rzeA-6g79S:
19.10