SIMILAR PATTERNS OF AMINO ACIDS FOR 3RXF_A_4APA9_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1a0j TRYPSIN

(Salmo salar) 		PF00089
(Trypsin) 		6 SER A 190
SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 226
 BEN  A 246 (-3.0A)
SO4  A 248 ( 2.5A)
None
None
BEN  A 246 ( 3.9A)
BEN  A 246 (-3.3A)
 0.32A 3rxfA-1a0jA:
41.6		 3rxfA-1a0jA:
73.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1a5i PLASMINOGEN
ACTIVATOR

(Desmodus
rotundus) 		PF00089
(Trypsin) 		4 SER A 195
TRP A 215
GLY A 216
GLY A 226
 0GJ  A 245 (-1.4A)
None
0GJ  A 245 (-3.5A)
0GJ  A 245 ( 4.2A)
 0.35A 3rxfA-1a5iA:
11.4		 3rxfA-1a5iA:
37.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1afq BOVINE
GAMMA-CHYMOTRYPSIN

(Bos taurus) 		PF00089
(Trypsin) 		6 SER C 190
SER C 195
VAL C 213
TRP C 215
GLY C 216
GLY C 226
 None
0FG  C 301 ( 3.0A)
None
None
0FG  C 301 (-3.4A)
0FG  C 301 ( 4.4A)
 0.61A 3rxfA-1afqC:
9.4		 3rxfA-1afqC:
22.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1bqy PLASMINOGEN
ACTIVATOR

(Trimeresurus
stejnegeri) 		PF00089
(Trypsin) 		5 SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 226
 0GJ  A   1 ( 1.4A)
None
None
0GJ  A   1 (-3.5A)
0GJ  A   1 ( 4.3A)
 0.30A 3rxfA-1bqyA:
15.3		 3rxfA-1bqyA:
42.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1bru ELASTASE

(Sus scrofa) 		PF00089
(Trypsin) 		4 SER P 190
SER P 195
VAL P 213
GLY P 216
 1NB  P   1 (-3.5A)
1NB  P   1 ( 1.2A)
None
1NB  P   1 ( 4.4A)
 0.31A 3rxfA-1bruP:
17.6		 3rxfA-1bruP:
40.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1dlk THROMBIN HEAVY CHAIN

(Bos taurus) 		PF00089
(Trypsin) 		5 SER B 190
SER B 195
VAL B 213
TRP B 215
GLY B 226
 None
 0.69A 3rxfA-1dlkB:
14.0		 3rxfA-1dlkB:
43.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1dlk THROMBIN HEAVY CHAIN

(Bos taurus) 		PF00089
(Trypsin) 		5 SER B 195
VAL B 213
TRP B 215
GLY B 216
GLY B 226
 None
 0.26A 3rxfA-1dlkB:
14.0		 3rxfA-1dlkB:
43.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ekb ENTEROPEPTIDASE

(Bos taurus) 		PF00089
(Trypsin) 		4 SER B 190
SER B 195
GLY B 216
GLY B 226
 None
 0.31A 3rxfA-1ekbB:
14.6		 3rxfA-1ekbB:
36.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1elv COMPLEMENT C1S
COMPONENT

(Homo sapiens) 		PF00084
(Sushi)
PF00089
(Trypsin) 		6 SER A 612
SER A 617
VAL A 638
TRP A 640
GLY A 641
GLY A 648
 None
SO4  A2001 ( 2.7A)
None
None
None
None
 0.38A 3rxfA-1elvA:
12.7		 3rxfA-1elvA:
30.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ept PORCINE E-TRYPSIN

(Sus scrofa) 		PF00089
(Trypsin) 		6 SER C 190
SER C 195
VAL C 213
TRP C 215
GLY C 216
GLY C 226
 None
 0.29A 3rxfA-1eptC:
13.0		 3rxfA-1eptC:
81.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1euf DUODENASE

(Bos taurus) 		PF00089
(Trypsin) 		4 SER A 190
SER A 195
VAL A 213
GLY A 216
 None
 0.39A 3rxfA-1eufA:
13.2		 3rxfA-1eufA:
38.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1fi8 NATURAL KILLER CELL
PROTEASE 1

(Rattus
norvegicus) 		PF00089
(Trypsin) 		4 SER A 190
SER A 195
VAL A 213
GLY A 216
 None
 0.41A 3rxfA-1fi8A:
13.4		 3rxfA-1fi8A:
38.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1fiw BETA-ACROSIN HEAVY
CHAIN

(Ovis aries) 		PF00089
(Trypsin) 		4 SER A 195
TRP A 215
GLY A 216
GLY A 226
 PBZ  A 305 (-2.9A)
None
PBZ  A 305 (-3.4A)
PBZ  A 305 (-3.3A)
 0.28A 3rxfA-1fiwA:
16.9		 3rxfA-1fiwA:
34.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1fiz BETA-ACROSIN HEAVY
CHAIN

(Sus scrofa) 		PF00089
(Trypsin) 		4 SER A 195
TRP A 215
GLY A 216
GLY A 226
 PBZ  A 308 (-3.2A)
None
PBZ  A 308 (-3.6A)
PBZ  A 308 ( 3.7A)
 0.28A 3rxfA-1fizA:
16.5		 3rxfA-1fizA:
37.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1fq3 GRANZYME B

(Homo sapiens) 		PF00089
(Trypsin) 		4 SER A 190
SER A 195
VAL A 213
GLY A 216
 None
SO4  A 800 (-2.4A)
None
None
 0.73A 3rxfA-1fq3A:
12.6		 3rxfA-1fq3A:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1fxy COAGULATION FACTOR
XA-TRYPSIN CHIMERA

(Homo sapiens) 		PF00089
(Trypsin) 		6 SER A 190
SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 226
 0G6  A   1 (-2.8A)
0G6  A   1 (-1.4A)
None
None
0G6  A   1 (-3.9A)
0G6  A   1 (-3.3A)
 0.35A 3rxfA-1fxyA:
38.1		 3rxfA-1fxyA:
55.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gvl KALLIKREIN 6

(Homo sapiens) 		PF00089
(Trypsin) 		5 SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 226
 None
 0.55A 3rxfA-1gvlA:
28.4		 3rxfA-1gvlA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1h4w TRYPSIN IVA

(Homo sapiens) 		PF00089
(Trypsin) 		6 SER A 190
SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 226
 BEN  A 250 (-2.9A)
BEN  A 250 (-3.6A)
None
None
BEN  A 250 (-3.9A)
BEN  A 250 (-3.3A)
 0.23A 3rxfA-1h4wA:
43.3		 3rxfA-1h4wA:
72.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1h9h TRYPSIN

(Sus scrofa) 		PF00089
(Trypsin) 		6 SER E 190
SER E 195
VAL E 213
TRP E 215
GLY E 216
GLY E 226
 None
 0.36A 3rxfA-1h9hE:
43.7		 3rxfA-1h9hE:
82.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1id5 THROMBIN

(Bos taurus) 		PF00089
(Trypsin) 		5 SER H 195
VAL H 213
TRP H 215
GLY H 216
GLY H 226
 None
 0.47A 3rxfA-1id5H:
13.3		 3rxfA-1id5H:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1j17 TRYPSIN II, ANIONIC

(Rattus
norvegicus) 		PF00089
(Trypsin) 		5 SER T 195
VAL T 213
TRP T 215
GLY T 216
GLY T 226
 SO4  T 600 ( 2.6A)
ZEN  T   1 (-4.1A)
ZEN  T   1 (-3.4A)
ZEN  T   1 (-3.7A)
ZEN  T   1 (-3.7A)
 0.18A 3rxfA-1j17T:
43.1		 3rxfA-1j17T:
71.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1kig FACTOR XA

(Bos taurus) 		PF00089
(Trypsin) 		5 SER H 195
VAL H 213
TRP H 215
GLY H 216
GLY H 226
 None
 0.37A 3rxfA-1kigH:
13.3		 3rxfA-1kigH:
40.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kvk MEVALONATE KINASE

(Rattus
norvegicus) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C) 		4 SER A 208
SER A 150
GLY A 144
GLY A  12
 None
None
ATP  A 535 ( 3.2A)
None
 0.71A 3rxfA-1kvkA:
undetectable		 3rxfA-1kvkA:
21.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1mbq TRYPSIN

(Oncorhynchus
keta) 		PF00089
(Trypsin) 		6 SER A 190
SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 226
 BEN  A1222 (-2.9A)
BEN  A1222 (-3.5A)
None
None
BEN  A1222 (-3.9A)
BEN  A1222 (-3.4A)
 0.30A 3rxfA-1mbqA:
41.2		 3rxfA-1mbqA:
65.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1mkx PRETHROMBIN-2

(Bos taurus) 		PF00089
(Trypsin)
PF09396
(Thrombin_light) 		4 SER K 195
VAL K 213
TRP K 215
GLY K 226
 None
 0.37A 3rxfA-1mkxK:
27.8		 3rxfA-1mkxK:
37.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1npm NEUROPSIN

(Mus musculus) 		PF00089
(Trypsin) 		4 SER A 195
TRP A 215
GLY A 216
GLY A 226
 None
 0.36A 3rxfA-1npmA:
15.8		 3rxfA-1npmA:
45.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1o5f SERINE PROTEASE
HEPSIN

(Homo sapiens) 		PF00089
(Trypsin) 		5 SER H 195
VAL H 213
TRP H 215
GLY H 216
GLY H 226
 CR9  H 256 (-1.5A)
CR9  H 256 (-4.3A)
None
CR9  H 256 ( 3.8A)
CR9  H 256 (-3.0A)
 0.22A 3rxfA-1o5fH:
19.1		 3rxfA-1o5fH:
41.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1op2 VENOM SERINE
PROTEINASE

(Deinagkistrodon
acutus) 		PF00089
(Trypsin) 		4 SER A 195
VAL A 213
GLY A 216
GLY A 226
 None
 0.38A 3rxfA-1op2A:
14.4		 3rxfA-1op2A:
41.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1orf GRANZYME A

(Homo sapiens) 		PF00089
(Trypsin) 		4 SER A 190
SER A 195
GLY A 216
GLY A 226
 0G6  A   1 (-2.9A)
0G6  A   1 (-1.3A)
0G6  A   1 (-3.3A)
0G6  A   1 (-3.5A)
 0.28A 3rxfA-1orfA:
13.7		 3rxfA-1orfA:
35.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1pfx FACTOR IXA

(Sus scrofa) 		PF00089
(Trypsin) 		5 SER C 190
SER C 195
TRP C 215
GLY C 216
GLY C 226
 0G6  C 301 (-2.6A)
0G6  C 301 (-1.4A)
None
0G6  C 301 (-3.2A)
0G6  C 301 ( 3.5A)
 0.41A 3rxfA-1pfxC:
13.9		 3rxfA-1pfxC:
43.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1pq5 TRYPSIN

(Fusarium
oxysporum) 		PF00089
(Trypsin) 		6 SER A 190
SER A 195
VAL A 210
TRP A 212
GLY A 213
GLY A 223
 ARG  A 703 (-2.5A)
ARG  A 703 (-2.3A)
ARG  A 703 (-4.5A)
None
ARG  A 703 ( 3.7A)
ARG  A 703 (-2.6A)
 0.38A 3rxfA-1pq5A:
17.6		 3rxfA-1pq5A:
44.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q3x MANNAN-BINDING
LECTIN SERINE
PROTEASE 2

(Homo sapiens) 		PF00084
(Sushi)
PF00089
(Trypsin) 		6 SER A 628
SER A 633
VAL A 653
TRP A 655
GLY A 656
GLY A 667
 GOL  A 701 (-3.4A)
GOL  A 701 (-3.0A)
GOL  A 701 (-4.9A)
None
GOL  A 701 ( 4.1A)
GOL  A 701 ( 4.0A)
 0.35A 3rxfA-1q3xA:
13.6		 3rxfA-1q3xA:
29.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1sgf NERVE GROWTH FACTOR

(Mus musculus) 		PF00089
(Trypsin) 		4 SER G 195
TRP G 215
GLY G 216
GLY G 226
 None
 0.39A 3rxfA-1sgfG:
15.4		 3rxfA-1sgfG:
41.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tnd TRANSDUCIN

(Bos taurus) 		PF00503
(G-alpha) 		4 SER A  40
SER A  43
GLY A 199
GLY A  36
 GSP  A 351 (-3.2A)
MG  A 352 ( 2.2A)
GSP  A 351 (-3.6A)
None
 0.71A 3rxfA-1tndA:
undetectable		 3rxfA-1tndA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w52 PANCREATIC LIPASE
RELATED PROTEIN 2

(Equus caballus) 		PF00151
(Lipase)
PF01477
(PLAT) 		5 SER X 105
VAL X  75
TRP X 108
GLY X  78
GLY X 156
 None
 1.47A 3rxfA-1w52X:
undetectable		 3rxfA-1w52X:
20.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ym0 FIBRINOTIC ENZYME
COMPONENT B

(Eisenia fetida) 		PF00089
(Trypsin) 		6 SER A 190
SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 226
 None
 0.30A 3rxfA-1ym0A:
14.1		 3rxfA-1ym0A:
39.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zca G ALPHA I/12

(Mus musculus) 		PF00503
(G-alpha) 		4 SER A  66
SER A  69
GLY A 228
GLY A  62
 GDP  A 382 (-2.9A)
MG  A 383 ( 2.1A)
ALF  A 384 (-3.3A)
None
 0.64A 3rxfA-1zcaA:
undetectable		 3rxfA-1zcaA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zjk MANNAN-BINDING
LECTIN SERINE
PROTEASE 2

(Homo sapiens) 		PF00084
(Sushi)
PF00089
(Trypsin) 		5 SER A 633
VAL A 653
TRP A 655
GLY A 656
GLY A 667
 None
 0.65A 3rxfA-1zjkA:
13.0		 3rxfA-1zjkA:
26.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1zlr COAGULATION FACTOR
XI

(Homo sapiens) 		PF00089
(Trypsin) 		4 SER A 195
TRP A 215
GLY A 216
GLY A 226
 368  A 901 (-1.4A)
None
368  A 901 (-3.6A)
368  A 901 (-3.5A)
 0.19A 3rxfA-1zlrA:
13.7		 3rxfA-1zlrA:
39.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2eek TRYPSIN-1

(Gadus morhua) 		PF00089
(Trypsin) 		6 SER A 190
SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 226
 BEN  A 301 (-2.8A)
BEN  A 301 (-3.4A)
None
None
BEN  A 301 ( 3.8A)
BEN  A 301 (-3.2A)
 0.24A 3rxfA-2eekA:
40.8		 3rxfA-2eekA:
62.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ei8 COAGULATION FACTOR
X, HEAVY CHAIN

(Homo sapiens) 		PF00089
(Trypsin) 		5 SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 226
 DT8  A 700 ( 3.9A)
DT8  A 700 ( 4.1A)
DT8  A 700 (-3.9A)
DT8  A 700 (-3.5A)
DT8  A 700 (-3.5A)
 0.35A 3rxfA-2ei8A:
14.1		 3rxfA-2ei8A:
38.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2f91 HEPATOPANCREAS
TRYPSIN

(Astacus
leptodactylus) 		PF00089
(Trypsin) 		6 SER A 190
SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 227
 None
 0.36A 3rxfA-2f91A:
14.6		 3rxfA-2f91A:
44.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ik8 GUANINE
NUCLEOTIDE-BINDING
PROTEIN G(I),
ALPHA-1 SUBUNIT

(Homo sapiens) 		PF00503
(G-alpha) 		4 SER A  44
SER A  47
GLY A 203
GLY A  40
 GDP  A 401 (-3.6A)
MG  A 356 ( 1.9A)
ALF  A 355 (-3.3A)
None
 0.71A 3rxfA-2ik8A:
undetectable		 3rxfA-2ik8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iou MAJOR TROPISM
DETERMINANT P1

(Bordetella
virus BPP1) 		no annotation 4 SER A 271
VAL A 276
GLY A 285
GLY A 273
 None
 0.73A 3rxfA-2iouA:
undetectable		 3rxfA-2iouA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jet CHYMOTRYPSINOGEN B
CHAIN C

(Rattus
norvegicus) 		PF00089
(Trypsin) 		5 SER C 195
VAL C 213
TRP C 215
GLY C 216
GLY C 226
 None
 0.61A 3rxfA-2jetC:
7.7		 3rxfA-2jetC:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2odp COMPLEMENT C2

(Homo sapiens) 		PF00089
(Trypsin)
PF00092
(VWA) 		4 SER A 659
VAL A 677
TRP A 679
GLY A 680
 None
 0.30A 3rxfA-2odpA:
21.6		 3rxfA-2odpA:
17.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2oq5 TRANSMEMBRANE
PROTEASE, SERINE 11E

(Homo sapiens) 		PF00089
(Trypsin) 		5 SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 226
 BEN  A 245 (-3.3A)
None
None
BEN  A 245 ( 3.8A)
BEN  A 245 (-3.4A)
 0.20A 3rxfA-2oq5A:
14.9		 3rxfA-2oq5A:
37.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2owm RELATED TO
KINESIN-LIKE PROTEIN
KIF1C

(Neurospora
crassa) 		PF00225
(Kinesin) 		4 SER A 148
SER A 151
GLY A 302
GLY A 144
 ADP  A1002 (-3.4A)
MG  A1001 ( 1.9A)
None
None
 0.68A 3rxfA-2owmA:
undetectable		 3rxfA-2owmA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pks THROMBIN HEAVY CHAIN
FRAGMENT

(Homo sapiens) 		PF00089
(Trypsin) 		5 SER C 235
VAL C 255
TRP C 257
GLY C 258
GLY C 268
 G44  C 101 (-3.5A)
None
G44  C 101 (-4.1A)
G44  C 101 (-3.3A)
G44  C 101 (-3.0A)
 0.27A 3rxfA-2pksC:
9.8		 3rxfA-2pksC:
21.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2psy KALLIKREIN-5

(Homo sapiens) 		PF00089
(Trypsin) 		6 SER A 190
SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 226
 None
 0.37A 3rxfA-2psyA:
15.2		 3rxfA-2psyA:
47.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q3f RAS-RELATED
GTP-BINDING PROTEIN
D

(Homo sapiens) 		PF04670
(Gtr1_RagA) 		4 SER A  54
SER A  57
GLY A 101
GLY A  50
 GNP  A 401 (-3.5A)
MG  A 301 ( 2.1A)
GNP  A 401 (-3.2A)
None
 0.68A 3rxfA-2q3fA:
undetectable		 3rxfA-2q3fA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qi9 VITAMIN B12 IMPORT
SYSTEM PERMEASE
PROTEIN BTUC

(Escherichia
coli) 		PF01032
(FecCD) 		5 SER A  94
SER A 246
VAL A 243
GLY A 254
GLY A  89
 None
 1.34A 3rxfA-2qi9A:
undetectable		 3rxfA-2qi9A:
19.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qy0 COMPLEMENT C1R
SUBCOMPONENT

(Homo sapiens) 		PF00089
(Trypsin) 		5 SER B 637
VAL B 657
TRP B 659
GLY B 660
GLY B 668
 None
 0.22A 3rxfA-2qy0B:
13.2		 3rxfA-2qy0B:
32.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2r0l HEPATOCYTE GROWTH
FACTOR ACTIVATOR

(Homo sapiens) 		PF00089
(Trypsin) 		4 SER A 195
TRP A 215
GLY A 216
GLY A 226
 None
 0.21A 3rxfA-2r0lA:
18.0		 3rxfA-2r0lA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2r2w PLASMINOGEN
ACTIVATOR, UROKINASE

(Homo sapiens) 		PF00089
(Trypsin) 		6 SER U 190
SER U 195
VAL U 213
TRP U 215
GLY U 216
GLY U 226
 4PG  U 300 (-2.7A)
4PG  U 300 (-3.5A)
None
None
4PG  U 300 (-3.3A)
4PG  U 300 (-3.2A)
 0.56A 3rxfA-2r2wU:
14.1		 3rxfA-2r2wU:
39.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2wpm COAGULATION FACTOR
IXA HEAVY CHAIN

(Homo sapiens) 		PF00089
(Trypsin) 		5 SER S 190
SER S 195
TRP S 215
GLY S 216
GLY S 226
 None
 0.43A 3rxfA-2wpmS:
14.2		 3rxfA-2wpmS:
41.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xtz GUANINE
NUCLEOTIDE-BINDING
PROTEIN ALPHA-1
SUBUNIT

(Arabidopsis
thaliana) 		PF00503
(G-alpha) 		4 SER A  49
SER A  52
GLY A 221
GLY A  45
 GSP  A1382 (-3.4A)
MG  A1381 ( 2.0A)
GSP  A1382 (-3.4A)
None
 0.63A 3rxfA-2xtzA:
undetectable		 3rxfA-2xtzA:
20.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2zec TRYPTASE BETA 2

(Homo sapiens) 		PF00089
(Trypsin) 		6 SER A 204
SER A 209
VAL A 227
TRP A 229
GLY A 230
GLY A 240
 11N  A   1 (-3.5A)
11N  A   1 (-3.3A)
None
None
11N  A   1 (-3.9A)
11N  A   1 (-3.6A)
 0.41A 3rxfA-2zecA:
13.5		 3rxfA-2zecA:
40.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aqp PROBABLE SECDF
PROTEIN-EXPORT
MEMBRANE PROTEIN

(Thermus
thermophilus) 		PF02355
(SecD_SecF)
PF07549
(Sec_GG) 		4 SER A 634
VAL A 601
GLY A 704
GLY A 708
 None
 0.73A 3rxfA-3aqpA:
undetectable		 3rxfA-3aqpA:
14.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3beu TRYPSIN

(Streptomyces
griseus) 		PF00089
(Trypsin) 		5 SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 226
 SO4  A 246 ( 2.5A)
None
None
BEN  A 247 (-3.7A)
BEN  A 247 (-3.5A)
 0.25A 3rxfA-3beuA:
17.4		 3rxfA-3beuA:
36.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cx6 GUANINE
NUCLEOTIDE-BINDING
PROTEIN ALPHA-13
SUBUNIT

(Mus musculus) 		PF00503
(G-alpha) 		4 SER A  59
SER A  62
GLY A 225
GLY A  55
 GDP  A 775 (-3.4A)
MG  A 675 ( 2.7A)
None
None
 0.62A 3rxfA-3cx6A:
undetectable		 3rxfA-3cx6A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cx6 GUANINE
NUCLEOTIDE-BINDING
PROTEIN ALPHA-13
SUBUNIT

(Mus musculus) 		PF00503
(G-alpha) 		5 SER A 268
SER A 248
VAL A 247
GLY A  57
GLY A  55
 None
None
None
GDP  A 775 ( 4.2A)
None
 1.21A 3rxfA-3cx6A:
undetectable		 3rxfA-3cx6A:
20.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3f6u VITAMIN K-DEPENDENT
PROTEIN C HEAVY
CHAIN

(Homo sapiens) 		PF00089
(Trypsin) 		5 SER H 195
VAL H 213
TRP H 215
GLY H 216
GLY H 226
 0G6  H   1 (-1.8A)
None
0G6  H   1 (-4.1A)
0G6  H   1 (-3.8A)
0G6  H   1 ( 3.9A)
 0.41A 3rxfA-3f6uH:
12.7		 3rxfA-3f6uH:
36.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3gov MASP-1

(Homo sapiens) 		PF00089
(Trypsin) 		5 SER B 646
VAL B 666
TRP B 668
GLY B 669
GLY B 679
 None
 0.43A 3rxfA-3govB:
14.1		 3rxfA-3govB:
35.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3gym PROSTASIN

(Homo sapiens) 		PF00089
(Trypsin) 		5 SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 226
 None
 0.36A 3rxfA-3gymA:
14.8		 3rxfA-3gymA:
40.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lzk FUMARYLACETOACETATE
HYDROLASE FAMILY
PROTEIN

(Sinorhizobium
meliloti) 		PF01557
(FAA_hydrolase) 		5 SER A 285
SER A 266
VAL A 265
GLY A 283
GLY A 229
 None
 1.48A 3rxfA-3lzkA:
undetectable		 3rxfA-3lzkA:
21.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3r3g THROMBIN HEAVY CHAIN

(Homo sapiens) 		PF00089
(Trypsin) 		5 SER B 195
VAL B 213
TRP B 215
GLY B 216
GLY B 226
 None
 0.35A 3rxfA-3r3gB:
13.5		 3rxfA-3r3gB:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3s69 THROMBIN-LIKE ENZYME
DEFIBRASE

(Gloydius
saxatilis) 		PF00089
(Trypsin) 		4 SER A 195
VAL A 209
GLY A 212
GLY A 223
 None
 0.38A 3rxfA-3s69A:
14.7		 3rxfA-3s69A:
44.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t34 DYNAMIN-RELATED
PROTEIN 1A, LINKER,
DYNAMIN-RELATED
PROTEIN 1A

(Arabidopsis
thaliana) 		PF00350
(Dynamin_N)
PF01031
(Dynamin_M) 		4 SER A  45
SER A  48
GLY A 145
GLY A  41
 GDP  A1000 (-3.9A)
MG  A1002 ( 2.3A)
ALF  A1001 (-3.5A)
None
 0.73A 3rxfA-3t34A:
undetectable		 3rxfA-3t34A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vta CUCUMISIN

(Cucumis melo) 		PF00082
(Peptidase_S8) 		5 SER A 527
SER A 304
VAL A 325
GLY A 523
GLY A 496
 None
DFP  A 801 (-3.4A)
None
DFP  A 801 (-3.1A)
None
 1.43A 3rxfA-3vtaA:
undetectable		 3rxfA-3vtaA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w6o DYNAMIN-1-LIKE
PROTEIN

(Homo sapiens) 		PF00350
(Dynamin_N)
PF01031
(Dynamin_M) 		4 SER A  36
SER A  39
GLY A 149
GLY A  32
 GCP  A 801 (-4.0A)
MG  A 802 ( 2.0A)
GCP  A 801 (-3.6A)
None
 0.73A 3rxfA-3w6oA:
undetectable		 3rxfA-3w6oA:
21.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w94 ENTEROPEPTIDASE-1

(Oryzias latipes) 		PF00089
(Trypsin) 		4 SER A 974
SER A 979
GLY A1000
GLY A1010
 None
 0.29A 3rxfA-3w94A:
15.2		 3rxfA-3w94A:
35.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zjc GTPASE IMAP FAMILY
MEMBER 7

(Homo sapiens) 		PF04548
(AIG1) 		4 SER A  19
SER A  22
GLY A  66
GLY A  15
 GNP  A1297 (-3.9A)
MG  A1296 ( 2.4A)
GNP  A1297 ( 4.3A)
None
 0.68A 3rxfA-3zjcA:
undetectable		 3rxfA-3zjcA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bxw FACTOR XA

(Pseudonaja
textilis) 		PF00089
(Trypsin)
PF14670
(FXa_inhibition) 		4 SER A 362
VAL A 380
GLY A 383
GLY A 393
 0GJ  A1411 (-1.4A)
None
0GJ  A1411 (-3.7A)
0GJ  A1411 (-3.3A)
 0.34A 3rxfA-4bxwA:
13.5		 3rxfA-4bxwA:
23.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4dgj ENTEROPEPTIDASE
CATALYTIC LIGHT
CHAIN

(Homo sapiens) 		PF00089
(Trypsin) 		4 SER A 182
SER A 187
GLY A 208
GLY A 218
 None
 0.67A 3rxfA-4dgjA:
14.9		 3rxfA-4dgjA:
37.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e5v PUTATIVE THUA-LIKE
PROTEIN

(Parabacteroides
merdae) 		PF06283
(ThuA) 		5 SER A 144
SER A 123
TRP A 137
GLY A 136
GLY A 164
 None
None
EDO  A 403 (-3.8A)
None
None
 1.43A 3rxfA-4e5vA:
undetectable		 3rxfA-4e5vA:
21.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4fxg MANNAN-BINDING
LECTIN SERINE
PROTEASE 2 B CHAIN

(Homo sapiens) 		PF00089
(Trypsin) 		5 SER H 628
VAL H 653
TRP H 655
GLY H 656
GLY H 667
 None
 0.44A 3rxfA-4fxgH:
14.4		 3rxfA-4fxgH:
36.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4gso THROMBIN-LIKE ENZYME
BJUSSUSP-1

(Bothrops
jararacussu) 		PF00089
(Trypsin) 		4 SER A 178
VAL A 192
GLY A 195
GLY A 206
 None
 0.00A 3rxfA-4gsoA:
undetectable		 3rxfA-4gsoA:
44.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4igd MANNAN-BINDING
LECTIN SERINE
PROTEASE 1

(Homo sapiens) 		PF00084
(Sushi)
PF00089
(Trypsin) 		4 SER A 646
VAL A 666
TRP A 668
GLY A 679
 None
None
GOL  A 702 (-3.9A)
None
 0.32A 3rxfA-4igdA:
9.2		 3rxfA-4igdA:
28.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4iw4 MANNAN-BINDING
LECTIN SERINE
PROTEASE 3

(Homo sapiens) 		PF00089
(Trypsin) 		5 SER E 645
VAL E 665
TRP E 667
GLY E 668
GLY E 680
 None
 0.34A 3rxfA-4iw4E:
13.7		 3rxfA-4iw4E:
34.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4k8y KALLIKREIN-4

(Homo sapiens) 		PF00089
(Trypsin) 		5 SER A 190
SER A 195
VAL A 213
GLY A 216
GLY A 226
 None
 0.49A 3rxfA-4k8yA:
14.5		 3rxfA-4k8yA:
40.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kkd MANNAN-BINDING
LECTIN SERINE
PROTEASE 1

(Homo sapiens) 		PF00084
(Sushi)
PF00089
(Trypsin) 		4 VAL A 684
TRP A 686
GLY A 687
GLY A 699
 None
 0.55A 3rxfA-4kkdA:
8.9		 3rxfA-4kkdA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lk4 VESB PROTEASE

(Vibrio cholerae) 		PF00089
(Trypsin) 		4 VAL A 237
TRP A 239
GLY A 240
GLY A 251
 None
 0.37A 3rxfA-4lk4A:
27.3		 3rxfA-4lk4A:
26.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspora
erythraea) 		PF00089
(Trypsin) 		4 SER A 179
TRP A 195
GLY A 196
GLY A 206
 None
 0.15A 3rxfA-4m7gA:
14.6		 3rxfA-4m7gA:
40.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qed ELXO

(Staphylococcus
epidermidis) 		PF13561
(adh_short_C2) 		4 SER A 139
VAL A 160
GLY A 154
GLY A 143
 None
 0.72A 3rxfA-4qedA:
undetectable		 3rxfA-4qedA:
21.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4r0i SUPPRESSOR OF
TUMORIGENICITY 14
PROTEIN

(Homo sapiens) 		PF00089
(Trypsin) 		6 SER A 190
SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 226
 3KM  A 900 (-2.9A)
3KM  A 900 (-3.6A)
None
None
3KM  A 900 (-3.4A)
3KM  A 900 (-3.2A)
 0.24A 3rxfA-4r0iA:
15.1		 3rxfA-4r0iA:
40.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4wwy TRYPSIN-1

(Homo sapiens) 		PF00089
(Trypsin) 		6 SER A 190
SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 226
 None
 0.32A 3rxfA-4wwyA:
42.3		 3rxfA-4wwyA:
74.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ylq COAGULATION FACTOR
VII

(Homo sapiens) 		PF00089
(Trypsin) 		6 SER H 190
SER H 195
VAL H 213
TRP H 215
GLY H 216
GLY H 226
 0Z7  H 501 (-2.3A)
0Z7  H 501 (-1.4A)
0Z7  H 501 ( 4.7A)
TMA  H 508 ( 3.9A)
0Z7  H 501 (-3.4A)
0Z7  H 501 (-3.0A)
 0.37A 3rxfA-4ylqH:
14.5		 3rxfA-4ylqH:
40.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5f8z PLASMA KALLIKREIN
LIGHT CHAIN

(Homo sapiens) 		PF00089
(Trypsin) 		4 SER A 195
TRP A 215
GLY A 216
GLY A 226
 None
 0.45A 3rxfA-5f8zA:
17.3		 3rxfA-5f8zA:
41.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5fah KALLIKREIN-7

(Homo sapiens) 		PF00089
(Trypsin) 		5 SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 226
 5VT  A 302 (-4.0A)
None
None
5VT  A 302 (-3.4A)
5VT  A 302 ( 4.3A)
 0.82A 3rxfA-5fahA:
16.2		 3rxfA-5fahA:
43.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ms3 KALLIKREIN-8

(Homo sapiens) 		no annotation 4 SER A 195
TRP A 215
GLY A 216
GLY A 226
 None
 0.25A 3rxfA-5ms3A:
15.4		 3rxfA-5ms3A:
34.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5o32 COMPLEMENT FACTOR I

(Homo sapiens) 		PF00089
(Trypsin) 		4 VAL I 544
TRP I 546
GLY I 547
GLY I 557
 None
 0.45A 3rxfA-5o32I:
11.9		 3rxfA-5o32I:
32.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5to3 PROTHROMBIN,THROMBOM
ODULIN

(Homo sapiens) 		PF00089
(Trypsin)
PF09064
(Tme5_EGF_like) 		4 SER B 220
VAL B 240
GLY B 243
GLY B 253
 0G6  B 501 (-1.3A)
None
0G6  B 501 (-3.7A)
0G6  B 501 (-3.6A)
 0.25A 3rxfA-5to3B:
17.8		 3rxfA-5to3B:
27.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ubk ACYL-HOMOSERINE
LACTONE ACYLASE PVDQ

(Pseudomonas
aeruginosa) 		PF01804
(Penicil_amidase) 		4 SER A 327
VAL A 325
GLY A 456
GLY A 454
 None
None
83M  A 801 (-4.8A)
None
 0.74A 3rxfA-5ubkA:
undetectable		 3rxfA-5ubkA:
16.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ubm COMPLEMENT C1S
SUBCOMPONENT

(Homo sapiens) 		no annotation 6 SER A 627
SER A 632
VAL A 653
TRP A 655
GLY A 656
GLY A 663
 None
 0.53A 3rxfA-5ubmA:
12.6		 3rxfA-5ubmA:
34.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xrf SNAKE VENOM SERINE
PROTEASE DA-36

(Deinagkistrodon
acutus) 		no annotation 4 SER A 206
VAL A 220
GLY A 223
GLY A 234
 None
 0.63A 3rxfA-5xrfA:
14.6		 3rxfA-5xrfA:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zfh KALLIKREIN-7

(Mus musculus) 		no annotation 5 SER A 195
VAL A 213
TRP A 215
GLY A 216
GLY A 226
 None
 0.30A 3rxfA-5zfhA:
15.6		 3rxfA-5zfhA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6au6 GUANINE
NUCLEOTIDE-BINDING
PROTEIN G(S) SUBUNIT
ALPHA ISOFORMS SHORT

(Homo sapiens) 		no annotation 4 SER A  51
SER A  54
GLY A 226
GLY A  47
 GDP  A 401 (-3.4A)
MG  A 402 ( 2.1A)
None
None
 0.61A 3rxfA-6au6A:
undetectable		 3rxfA-6au6A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b74 COAGULATION FACTOR
XII

(Homo sapiens) 		no annotation 4 SER B 195
TRP B 215
GLY B 216
GLY B 226
 SO4  B 304 ( 2.5A)
None
BEN  B 301 (-3.3A)
BEN  B 301 (-3.1A)
 0.24A 3rxfA-6b74B:
14.3		 3rxfA-6b74B:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoq DIPEPTIDYL PEPTIDASE
9

(Homo sapiens) 		no annotation 5 SER A 736
VAL A 643
TRP A 729
GLY A 753
GLY A 733
 None
 1.40A 3rxfA-6eoqA:
undetectable		 3rxfA-6eoqA:
14.88