SIMILAR PATTERNS OF AMINO ACIDS FOR 3RV5_A_DXCA91_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cp9 PENICILLIN G AMIDASE

(Providencia
rettgeri) 		PF01804
(Penicil_amidase) 		3 PHE B  24
GLN B 464
PHE B  57
 None
 0.84A 3rv5A-1cp9B:
1.0		 3rv5A-1cp9B:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ek2 EPOXIDE HYDROLASE

(Mus musculus) 		PF00561
(Abhydrolase_1)
PF13419
(HAD_2) 		3 PHE A 458
GLN A 382
PHE A 403
 None
CDU  A1100 (-3.5A)
None
 0.84A 3rv5A-1ek2A:
undetectable		 3rv5A-1ek2A:
9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1guq GALACTOSE-1-PHOSPHAT
E
URIDYLYLTRANSFERASE

(Escherichia
coli) 		PF01087
(GalP_UDP_transf)
PF02744
(GalP_UDP_tr_C) 		3 PHE A 270
GLN A  37
PHE A 231
 None
 0.74A 3rv5A-1guqA:
0.0		 3rv5A-1guqA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j71 ASPARTIC PROTEINASE

(Candida
tropicalis) 		PF00026
(Asp) 		3 PHE A 111
GLN A 148
PHE A  65
 None
 0.82A 3rv5A-1j71A:
undetectable		 3rv5A-1j71A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rpw TRANSCRIPTIONAL
REGULATOR QACR

(Staphylococcus
aureus) 		PF00440
(TetR_N)
PF08360
(TetR_C_5) 		3 PHE A  79
GLN A  62
PHE A 178
 None
 0.70A 3rv5A-1rpwA:
undetectable		 3rv5A-1rpwA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rpw TRANSCRIPTIONAL
REGULATOR QACR

(Staphylococcus
aureus) 		PF00440
(TetR_N)
PF08360
(TetR_C_5) 		3 PHE A 131
GLN A  62
PHE A 182
 None
 0.59A 3rv5A-1rpwA:
undetectable		 3rv5A-1rpwA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sw6 REGULATORY PROTEIN
SWI6

(Saccharomyces
cerevisiae) 		PF00023
(Ank)
PF13857
(Ank_5) 		3 PHE A 253
GLN A 246
PHE A 292
 None
 0.76A 3rv5A-1sw6A:
0.0		 3rv5A-1sw6A:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v10 LACCASE

(Rigidoporus
microporus) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 PHE A  97
GLN A  84
PHE A 124
 None
 0.82A 3rv5A-1v10A:
undetectable		 3rv5A-1v10A:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ylx HYPOTHETICAL PROTEIN
APC35702

(Geobacillus
stearothermophilus) 		no annotation 3 PHE A  13
GLN A  91
PHE A  60
 None
 0.79A 3rv5A-1ylxA:
undetectable		 3rv5A-1ylxA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ap1 PUTATIVE REGULATOR
PROTEIN

(Salmonella
enterica) 		PF00480
(ROK) 		3 PHE A 194
GLN A 204
PHE A 258
 None
 0.80A 3rv5A-2ap1A:
undetectable		 3rv5A-2ap1A:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dml PROTEIN
DISULFIDE-ISOMERASE
A6

(Mus musculus) 		PF00085
(Thioredoxin) 		3 PHE A  27
GLN A  79
PHE A  96
 None
 0.83A 3rv5A-2dmlA:
undetectable		 3rv5A-2dmlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eja UROPORPHYRINOGEN
DECARBOXYLASE

(Aquifex
aeolicus) 		PF01208
(URO-D) 		3 PHE A  73
GLN A 188
PHE A  44
 None
 0.76A 3rv5A-2ejaA:
0.0		 3rv5A-2ejaA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ghj 50S RIBOSOMAL
PROTEIN L20

(Aquifex
aeolicus) 		PF00453
(Ribosomal_L20) 		3 PHE A  77
GLN A 116
PHE A 104
 None
 0.83A 3rv5A-2ghjA:
undetectable		 3rv5A-2ghjA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j0n INVASIN IPAD

(Shigella
flexneri) 		PF06511
(IpaD) 		3 PHE A 167
GLN A 295
PHE A 283
 None
 0.72A 3rv5A-2j0nA:
1.7		 3rv5A-2j0nA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o6f 34 KDA MEMBRANE
ANTIGEN

(Treponema
pallidum) 		PF10634
(Iron_transport) 		3 PHE A 131
GLN A  61
PHE A 178
 None
 0.59A 3rv5A-2o6fA:
undetectable		 3rv5A-2o6fA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ogs THERMOSTABLE
CARBOXYLESTERASE
EST50

(Geobacillus
stearothermophilus) 		PF00135
(COesterase) 		3 PHE A 371
GLN A 219
PHE A 314
 PHE  A 371 ( 1.3A)
GLN  A 219 ( 0.6A)
PHE  A 314 ( 1.3A)
 0.84A 3rv5A-2ogsA:
0.0		 3rv5A-2ogsA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p7n PATHOGENICITY ISLAND
1 EFFECTOR PROTEIN

(Chromobacterium
violaceum) 		PF06511
(IpaD) 		3 PHE A 214
GLN A 362
PHE A 350
 None
 0.82A 3rv5A-2p7nA:
0.4		 3rv5A-2p7nA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qpx PREDICTED
METAL-DEPENDENT
HYDROLASE OF THE
TIM-BARREL FOLD

(Lactobacillus
paracasei) 		PF04909
(Amidohydro_2) 		3 PHE A 314
GLN A 225
PHE A  94
 None
KCX  A 166 ( 4.9A)
None
 0.83A 3rv5A-2qpxA:
0.0		 3rv5A-2qpxA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r0h CGL3 LECTIN

(Coprinopsis
cinerea) 		PF00337
(Gal-bind_lectin) 		3 PHE A 145
GLN A 141
PHE A  93
 None
 0.59A 3rv5A-2r0hA:
undetectable		 3rv5A-2r0hA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rch CYTOCHROME P450 74A

(Arabidopsis
thaliana) 		PF00067
(p450) 		3 PHE A 484
GLN A 187
PHE A 209
 None
 0.84A 3rv5A-2rchA:
0.0		 3rv5A-2rchA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vcd OUTER MEMBRANE
PROTEIN MIP

(Legionella
pneumophila) 		PF00254
(FKBP_C)
PF01346
(FKBP_N) 		3 PHE A 126
GLN A  33
PHE A  65
 RAP  A 138 ( 4.7A)
None
RAP  A 138 (-3.5A)
 0.82A 3rv5A-2vcdA:
undetectable		 3rv5A-2vcdA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vz9 FATTY ACID SYNTHASE

(Sus scrofa) 		PF00107
(ADH_zinc_N)
PF00109
(ketoacyl-synt)
PF00698
(Acyl_transf_1)
PF02801
(Ketoacyl-synt_C)
PF08242
(Methyltransf_12)
PF08659
(KR)
PF14765
(PS-DH)
PF16197
(KAsynt_C_assoc) 		3 PHE A1880
GLN A1910
PHE A1532
 None
 0.85A 3rv5A-2vz9A:
undetectable		 3rv5A-2vz9A:
2.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w40 GLYCEROL KINASE,
PUTATIVE

(Plasmodium
falciparum) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		3 PHE A 350
GLN A  12
PHE A 346
 None
EDO  A1503 ( 4.8A)
None
 0.56A 3rv5A-2w40A:
undetectable		 3rv5A-2w40A:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xhe UNC18

(Monosiga
brevicollis) 		PF00995
(Sec1) 		3 PHE A 222
GLN A 197
PHE A 140
 None
 0.75A 3rv5A-2xheA:
undetectable		 3rv5A-2xheA:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xmz HYDROLASE,
ALPHA/BETA HYDROLASE
FOLD FAMILY

(Staphylococcus
aureus) 		PF00561
(Abhydrolase_1) 		3 PHE A  19
GLN A 173
PHE A  37
 None
 0.71A 3rv5A-2xmzA:
undetectable		 3rv5A-2xmzA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xn1 ALPHA-GALACTOSIDASE

(Lactobacillus
acidophilus) 		PF02065
(Melibiase)
PF16874
(Glyco_hydro_36C)
PF16875
(Glyco_hydro_36N) 		3 PHE A 284
GLN A 500
PHE A 294
 None
 0.79A 3rv5A-2xn1A:
undetectable		 3rv5A-2xn1A:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xrc HUMAN COMPLEMENT
FACTOR I

(Homo sapiens) 		PF00057
(Ldl_recept_a)
PF00089
(Trypsin)
PF00530
(SRCR) 		3 PHE A  94
GLN A  70
PHE A 180
 None
 0.76A 3rv5A-2xrcA:
undetectable		 3rv5A-2xrcA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xwu IMPORTIN13

(Homo sapiens) 		PF03810
(IBN_N)
PF08389
(Xpo1) 		3 PHE B 828
GLN B 876
PHE B 779
 None
 0.74A 3rv5A-2xwuB:
undetectable		 3rv5A-2xwuB:
6.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yeq ALKALINE PHOSPHATASE
D

(Bacillus
subtilis) 		PF09423
(PhoD)
PF16655
(PhoD_N) 		3 PHE A 393
GLN A 481
PHE A 334
 None
 0.81A 3rv5A-2yeqA:
undetectable		 3rv5A-2yeqA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ynx LACA THIOREDOXIN

(synthetic
construct) 		PF00085
(Thioredoxin) 		3 PHE A  10
GLN A   4
PHE A  79
 None
 0.81A 3rv5A-2ynxA:
undetectable		 3rv5A-2ynxA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a2l HALOALKANE
DEHALOGENASE

(Bradyrhizobium
japonicum) 		PF00561
(Abhydrolase_1) 		3 PHE A 157
GLN A 147
PHE A 176
 None
None
CL  A 401 ( 4.8A)
 0.81A 3rv5A-3a2lA:
undetectable		 3rv5A-3a2lA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b57 LIN1889 PROTEIN

(Listeria
innocua) 		PF01966
(HD) 		3 PHE A 191
GLN A 185
PHE A 137
 None
 0.79A 3rv5A-3b57A:
undetectable		 3rv5A-3b57A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c2g SYS-1 PROTEIN

(Caenorhabditis
elegans) 		no annotation 3 PHE A 267
GLN A 318
PHE A 218
 None
 0.83A 3rv5A-3c2gA:
undetectable		 3rv5A-3c2gA:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c6l TCR 2W20 ALPHA CHAIN
TCR 2W20 BETA CHAIN

(Mus musculus;
Mus musculus) 		PF07686
(V-set)
PF09291
(DUF1968)
PF07654
(C1-set)
PF07686
(V-set) 		3 PHE B 101
GLN B  23
PHE A 101
 None
 0.71A 3rv5A-3c6lB:
undetectable		 3rv5A-3c6lB:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ctt MALTASE-GLUCOAMYLASE

(Homo sapiens) 		PF00088
(Trefoil)
PF01055
(Glyco_hydro_31)
PF16863
(NtCtMGAM_N) 		3 PHE A 234
GLN A  92
PHE A 529
 None
 0.81A 3rv5A-3cttA:
undetectable		 3rv5A-3cttA:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0r C3-DEGRADING
PROTEINASE (CPPA
PROTEIN)

(Streptococcus
pneumoniae) 		PF14506
(CppA_N)
PF14507
(CppA_C) 		3 PHE A 238
GLN A   5
PHE A 212
 None
 0.80A 3rv5A-3e0rA:
undetectable		 3rv5A-3e0rA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ebv CHINITASE A

(Streptomyces
coelicolor) 		PF00704
(Glyco_hydro_18) 		3 PHE A  64
GLN A  21
PHE A 113
 None
 0.78A 3rv5A-3ebvA:
undetectable		 3rv5A-3ebvA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fm2 UNCHARACTERIZED
PROTEIN, DISTANTLY
RELATED TO A HEME
BINDING/DEGRADING
HEMS (PF05171)
FAMILY

(Trichormus
variabilis) 		PF06228
(ChuX_HutX) 		3 PHE A  87
GLN A  92
PHE A   8
 None
 0.84A 3rv5A-3fm2A:
undetectable		 3rv5A-3fm2A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fnb ACYLAMINOACYL
PEPTIDASE SMU_737

(Streptococcus
mutans) 		PF12146
(Hydrolase_4) 		3 PHE A 238
GLN A 348
PHE A 205
 PGE  A 404 (-4.7A)
None
PGE  A 404 ( 4.5A)
 0.81A 3rv5A-3fnbA:
undetectable		 3rv5A-3fnbA:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g9g SUPPRESSOR OF YEAST
PROFILIN DELETION

(Saccharomyces
cerevisiae) 		no annotation 3 PHE A  89
GLN A  74
PHE A 249
 None
 0.83A 3rv5A-3g9gA:
undetectable		 3rv5A-3g9gA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0l GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Aquifex
aeolicus) 		PF01425
(Amidase) 		3 PHE A 178
GLN A 447
PHE A 402
 None
 0.82A 3rv5A-3h0lA:
undetectable		 3rv5A-3h0lA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0o BETA-GLUCANASE

(Fibrobacter
succinogenes) 		PF00722
(Glyco_hydro_16) 		3 PHE A 162
GLN A  96
PHE A 236
 None
 0.74A 3rv5A-3h0oA:
undetectable		 3rv5A-3h0oA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1n PROBABLE GLUTATHIONE
S-TRANSFERASE

(Bordetella
bronchiseptica) 		PF14497
(GST_C_3) 		3 PHE A  17
GLN A  67
PHE A 224
 None
 0.56A 3rv5A-3h1nA:
undetectable		 3rv5A-3h1nA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h5j 3-ISOPROPYLMALATE
DEHYDRATASE SMALL
SUBUNIT

(Mycobacterium
tuberculosis) 		PF00694
(Aconitase_C) 		3 PHE A  71
GLN A 117
PHE A  43
 None
 0.82A 3rv5A-3h5jA:
undetectable		 3rv5A-3h5jA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h68 SERINE/THREONINE-PRO
TEIN PHOSPHATASE 5

(Homo sapiens) 		PF00149
(Metallophos)
PF08321
(PPP5) 		3 PHE A 268
GLN A 342
PHE A 254
 None
 0.82A 3rv5A-3h68A:
undetectable		 3rv5A-3h68A:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hv0 TRYPTOPHANYL-TRNA
SYNTHETASE

(Cryptosporidium
parvum) 		PF00579
(tRNA-synt_1b) 		3 PHE A 322
GLN A 313
PHE A 386
 None
TRP  A   1 (-4.5A)
None
 0.78A 3rv5A-3hv0A:
undetectable		 3rv5A-3hv0A:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j0a TOLL-LIKE RECEPTOR 5

(Homo sapiens) 		PF01582
(TIR)
PF13855
(LRR_8) 		3 PHE A 177
GLN A 181
PHE A 166
 None
 0.85A 3rv5A-3j0aA:
undetectable		 3rv5A-3j0aA:
7.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jxe TRYPTOPHANYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00579
(tRNA-synt_1b) 		3 PHE A 204
GLN A 101
PHE A 158
 None
 0.73A 3rv5A-3jxeA:
undetectable		 3rv5A-3jxeA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lfv CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE

(Homo sapiens) 		PF01590
(GAF) 		3 PHE A 498
GLN A 504
PHE A 124
 None
 0.81A 3rv5A-3lfvA:
undetectable		 3rv5A-3lfvA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
elegans) 		PF02373
(JmjC) 		3 PHE A 578
GLN A 444
PHE A 373
 None
 0.80A 3rv5A-3n9oA:
undetectable		 3rv5A-3n9oA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pjl 34 KDA MEMBRANE
ANTIGEN

(Treponema
pallidum) 		PF10634
(Iron_transport) 		3 PHE A 131
GLN A  61
PHE A 178
 None
 0.61A 3rv5A-3pjlA:
undetectable		 3rv5A-3pjlA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rtx MRNA-CAPPING ENZYME

(Mus musculus) 		PF01331
(mRNA_cap_enzyme)
PF03919
(mRNA_cap_C) 		3 PHE A 367
GLN A 382
PHE A 329
 None
 0.83A 3rv5A-3rtxA:
undetectable		 3rv5A-3rtxA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sy8 ROCR

(Pseudomonas
aeruginosa) 		PF00072
(Response_reg)
PF00563
(EAL) 		3 PHE A 264
GLN A 314
PHE A 211
 None
 0.79A 3rv5A-3sy8A:
undetectable		 3rv5A-3sy8A:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v4y SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PP1-ALPHA CATALYTIC
SUBUNIT

(Homo sapiens) 		PF00149
(Metallophos)
PF16891
(STPPase_N) 		3 PHE A  76
GLN A 294
PHE A 118
 None
 0.74A 3rv5A-3v4yA:
undetectable		 3rv5A-3v4yA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vu2 1,4-ALPHA-GLUCAN-BRA
NCHING ENZYME,
CHLOROPLASTIC/AMYLOP
LASTIC

(Oryza sativa) 		PF00128
(Alpha-amylase)
PF02806
(Alpha-amylase_C)
PF02922
(CBM_48) 		3 PHE A 314
GLN A 291
PHE A 240
 None
 0.57A 3rv5A-3vu2A:
undetectable		 3rv5A-3vu2A:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wdg UNCHARACTERIZED
PROTEIN

(Staphylococcus
aureus) 		PF06106
(SAUGI) 		3 PHE B  69
GLN B  52
PHE B  91
 None
 0.80A 3rv5A-3wdgB:
undetectable		 3rv5A-3wdgB:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE

(Streptomyces
coelicolor) 		PF03664
(Glyco_hydro_62) 		3 PHE A 256
GLN A 364
PHE A 340
 None
CA  A 501 (-2.9A)
None
 0.73A 3rv5A-3wmyA:
undetectable		 3rv5A-3wmyA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zid TUBULIN/FTSZ, GTPASE

(Methanothrix
thermoacetophila) 		PF00091
(Tubulin) 		3 PHE A 107
GLN A  23
PHE A 221
 None
 0.83A 3rv5A-3zidA:
undetectable		 3rv5A-3zidA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4amt RENIN

(Homo sapiens) 		PF00026
(Asp)
PF07966
(A1_Propeptide) 		3 PHE A 151
GLN A 193
PHE A 107
 None
 0.83A 3rv5A-4amtA:
undetectable		 3rv5A-4amtA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190

(Saccharomyces
cerevisiae) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		3 PHE A 223
GLN A 126
PHE A 108
 None
 0.78A 3rv5A-4c3hA:
undetectable		 3rv5A-4c3hA:
4.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e54 DNA DAMAGE-BINDING
PROTEIN 2

(Homo sapiens) 		PF00400
(WD40) 		3 PHE B  94
GLN B  88
PHE B 400
 None
 0.84A 3rv5A-4e54B:
undetectable		 3rv5A-4e54B:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gjh TNF
RECEPTOR-ASSOCIATED
FACTOR 5

(Mus musculus) 		no annotation 3 PHE A 381
GLN A 344
PHE A 411
 None
 0.81A 3rv5A-4gjhA:
undetectable		 3rv5A-4gjhA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h8n CONJUGATED
POLYKETONE REDUCTASE
C2

(Candida
parapsilosis) 		PF00248
(Aldo_ket_red) 		3 PHE A 203
GLN A 196
PHE A 172
 None
 0.79A 3rv5A-4h8nA:
undetectable		 3rv5A-4h8nA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hum MULTIDRUG EFFLUX
PROTEIN

(Neisseria
gonorrhoeae) 		PF01554
(MatE) 		3 PHE A  63
GLN A 138
PHE A 210
 None
 0.76A 3rv5A-4humA:
undetectable		 3rv5A-4humA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m16 BARTONELLA EFFECTOR
PROTEIN (BEP)
SUBSTRATE OF VIRB
T4SS

(Bartonella sp.
AR 15-3) 		PF02661
(Fic) 		3 PHE A 119
GLN A 113
PHE A 165
 None
 0.66A 3rv5A-4m16A:
0.9		 3rv5A-4m16A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n2r ALPHA-L-ARABINOFURAN
OSIDASE UMABF62A

(Ustilago maydis) 		PF03664
(Glyco_hydro_62) 		3 PHE A  90
GLN A 198
PHE A 174
 None
CA  A 401 (-2.9A)
None
 0.77A 3rv5A-4n2rA:
undetectable		 3rv5A-4n2rA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o8o ALPHA-L-ARABINOFURAN
OSIDASE

(Streptomyces
thermoviolaceus) 		PF03664
(Glyco_hydro_62) 		3 PHE A 143
GLN A 251
PHE A 227
 None
CA  A 401 (-2.9A)
None
 0.74A 3rv5A-4o8oA:
undetectable		 3rv5A-4o8oA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pom THIOREDOXIN

(Homo sapiens) 		PF00085
(Thioredoxin) 		3 PHE A  11
GLN A   4
PHE A  80
 None
 0.65A 3rv5A-4pomA:
undetectable		 3rv5A-4pomA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qiw DNA-DIRECTED RNA
POLYMERASE
DNA-DIRECTED RNA
POLYMERASE SUBUNIT D

(Thermococcus
kodakarensis;
Thermococcus
kodakarensis) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5)
PF01000
(RNA_pol_A_bac)
PF01193
(RNA_pol_L) 		3 PHE D  55
GLN D 127
PHE B 757
 None
 0.82A 3rv5A-4qiwD:
undetectable		 3rv5A-4qiwD:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qts CRISPR TYPE
III-ASSOCIATED RAMP
PROTEIN CSM4

(Methanocaldococcus
jannaschii) 		PF03787
(RAMPs) 		3 PHE A  83
GLN A 129
PHE A 367
 None
 0.80A 3rv5A-4qtsA:
undetectable		 3rv5A-4qtsA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rkk LAFORIN

(Homo sapiens) 		PF00686
(CBM_20)
PF00782
(DSPc) 		3 PHE A   5
GLN A 293
PHE A  84
 None
 0.67A 3rv5A-4rkkA:
undetectable		 3rv5A-4rkkA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xai MALTOSE-BINDING
PERIPLASMIC
PROTEIN,TAILLESS
ORTHOLOG
GRUNGE, ISOFORM J

(Escherichia
coli;
Tribolium
castaneum;
Drosophila
melanogaster) 		PF00104
(Hormone_recep)
PF13416
(SBP_bac_8)
no annotation 		3 PHE A1379
GLN P1822
PHE A1240
 None
 0.80A 3rv5A-4xaiA:
1.9		 3rv5A-4xaiA:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y5j MINI SPINDLES TOG3

(Drosophila
melanogaster) 		no annotation 3 PHE A 731
GLN A 798
PHE A 719
 None
 0.83A 3rv5A-4y5jA:
undetectable		 3rv5A-4y5jA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y9w ASPARTIC ACID
ENDOPEPTIDASE SAPP2

(Candida
parapsilosis) 		PF00026
(Asp) 		3 PHE A 104
GLN A 141
PHE A  58
 None
 0.79A 3rv5A-4y9wA:
undetectable		 3rv5A-4y9wA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z2v AVIDIN FAMILY

(Hoeflea
phototrophica) 		PF01382
(Avidin) 		3 PHE A  32
GLN A  38
PHE A  98
 None
 0.80A 3rv5A-4z2vA:
undetectable		 3rv5A-4z2vA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a22 VESICULAR STOMATITIS
VIRUS L POLYMERASE

(Vesicular
stomatitis
virus) 		PF00946
(Mononeg_RNA_pol)
PF14314
(Methyltrans_Mon)
PF14318
(Mononeg_mRNAcap) 		3 PHE A 642
GLN A 674
PHE A 552
 None
 0.80A 3rv5A-5a22A:
undetectable		 3rv5A-5a22A:
3.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eb5 HNL ISOENZYME 5

(Prunus dulcis) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		3 PHE A 356
GLN A 155
PHE A 336
 None
 0.80A 3rv5A-5eb5A:
undetectable		 3rv5A-5eb5A:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h8k N-CARBAMOYLPUTRESCIN
E AMIDOHYDROLASE

(Medicago
truncatula) 		PF00795
(CN_hydrolase) 		3 PHE A 136
GLN A 161
PHE A  55
 None
 0.81A 3rv5A-5h8kA:
undetectable		 3rv5A-5h8kA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hax NUCLEOPORIN NUP170

(Chaetomium
thermophilum) 		PF08801
(Nucleoporin_N) 		3 PHE A 434
GLN A 454
PHE A 362
 None
 0.81A 3rv5A-5haxA:
1.3		 3rv5A-5haxA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i7p PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A,FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A

(Escherichia
coli;
Homo sapiens) 		PF00254
(FKBP_C) 		3 PHE A 146
GLN A   3
PHE A  36
 None
 0.79A 3rv5A-5i7pA:
undetectable		 3rv5A-5i7pA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k0u CAPSID PROTEIN VP2

(Rhinovirus C) 		PF00073
(Rhv) 		3 PHE C  92
GLN C 263
PHE C 106
 None
 0.84A 3rv5A-5k0uC:
undetectable		 3rv5A-5k0uC:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5klp ORF34

(Pseudomonas
syringae) 		PF03421
(Acetyltransf_14) 		3 PHE A 115
GLN A 139
PHE A 133
 None
 0.75A 3rv5A-5klpA:
0.6		 3rv5A-5klpA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m3x ANGIOTENSINOGEN

(Homo sapiens) 		no annotation 3 PHE A 258
GLN A 265
PHE A 286
 None
 0.69A 3rv5A-5m3xA:
undetectable		 3rv5A-5m3xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B

(Acinetobacter
calcoaceticus) 		no annotation 3 PHE A 382
GLN A 231
PHE A   9
 None
 0.78A 3rv5A-5minA:
undetectable		 3rv5A-5minA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4

(Homo sapiens) 		no annotation 3 PHE A 167
GLN A 180
PHE A 109
 PHE  A 167 ( 1.3A)
GLN  A 180 ( 0.6A)
PHE  A 109 ( 1.3A)
 0.80A 3rv5A-5nksA:
undetectable		 3rv5A-5nksA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o3w PEPTIDE CYCLASE 1

(Gypsophila
vaccaria) 		no annotation 3 PHE A 106
GLN A 103
PHE A  86
 None
 0.67A 3rv5A-5o3wA:
undetectable		 3rv5A-5o3wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oqm MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 31,MEDIATOR
OF RNA POLYMERASE II
TRANSCRIPTION
SUBUNIT 31

(Saccharomyces
cerevisiae) 		no annotation 3 PHE o  57
GLN o  49
PHE o  32
 None
 0.84A 3rv5A-5oqmo:
undetectable		 3rv5A-5oqmo:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5sva MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 31

(Saccharomyces
cerevisiae) 		PF05669
(Med31) 		3 PHE X  54
GLN X  46
PHE X  29
 None
 0.82A 3rv5A-5svaX:
undetectable		 3rv5A-5svaX:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ubj ALPHA-L-ARABINOFURAN
OSIDASE AXHA-2

(Aspergillus
nidulans) 		PF03664
(Glyco_hydro_62) 		3 PHE A 105
GLN A 213
PHE A 189
 None
CA  A 401 (-2.8A)
None
 0.75A 3rv5A-5ubjA:
undetectable		 3rv5A-5ubjA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uhe DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA'

(Mycobacterium
tuberculosis) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		3 PHE D 532
GLN D1001
PHE D 512
 None
 0.64A 3rv5A-5uheD:
1.0		 3rv5A-5uheD:
5.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5viy BG1 FAB HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 PHE H 114
GLN H 111
PHE H  50
 None
 0.47A 3rv5A-5viyH:
undetectable		 3rv5A-5viyH:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x3j GLYCOSIDE HYDROLASE
FAMILY 31

(Kribbella
flavida) 		no annotation 3 PHE A 568
GLN A 654
PHE A 722
 None
 0.84A 3rv5A-5x3jA:
undetectable		 3rv5A-5x3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xno LIGHT HARVESTING
CHLOROPHYLL
A/B-BINDING PROTEIN
LHCB6, CP24

(Pisum sativum) 		no annotation 3 PHE 4 194
GLN 4 200
PHE 4  69
 LUT  4 620 (-4.4A)
None
None
 0.74A 3rv5A-5xno4:
undetectable		 3rv5A-5xno4:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yb7 L-AMINO ACID
OXIDASE/MONOOXYGENAS
E

(Pseudomonas sp.
AIU 813) 		no annotation 3 PHE A 491
GLN A 495
PHE A  22
 None
 0.76A 3rv5A-5yb7A:
undetectable		 3rv5A-5yb7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yem CATALASE

(Mycothermus
thermophilus) 		no annotation 3 PHE A 247
GLN A 251
PHE A 143
 None
 0.83A 3rv5A-5yemA:
undetectable		 3rv5A-5yemA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z03 MUREIN TETRAPEPTIDE
CARBOXYPEPTIDASE

(Escherichia
coli) 		no annotation 3 PHE A 146
GLN A 272
PHE A   4
 None
 0.84A 3rv5A-5z03A:
undetectable		 3rv5A-5z03A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bdt CALPAIN-3

(Homo sapiens) 		no annotation 3 PHE A 231
GLN A 142
PHE A 131
 None
 0.53A 3rv5A-6bdtA:
undetectable		 3rv5A-6bdtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6btm ALTERNATIVE COMPLEX
III SUBUNIT C
ALTERNATIVE COMPLEX
III SUBUNIT F

(Flavobacterium
johnsoniae;
Flavobacterium
johnsoniae) 		no annotation
no annotation 		3 PHE F 321
GLN C 105
PHE F 287
 None
 0.78A 3rv5A-6btmF:
0.5		 3rv5A-6btmF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6coy CHLORIDE CHANNEL
PROTEIN 1

(Homo sapiens) 		no annotation 3 PHE A 428
GLN A 445
PHE A 488
 None
 0.79A 3rv5A-6coyA:
undetectable		 3rv5A-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eq8 PERIPLASMIC
ALPHA-GALACTOSIDE-BI
NDING PROTEIN

(Agrobacterium
tumefaciens) 		no annotation 3 PHE D 572
GLN D 600
PHE D 371
 None
 0.75A 3rv5A-6eq8D:
undetectable		 3rv5A-6eq8D:
undetectable