SIMILAR PATTERNS OF AMINO ACIDS FOR 3RQO_B_H4BB600_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kex | NEUROPILIN-1 (Homo sapiens) |
PF00754(F5_F8_type_C) | 4 | TRP A 97PHE A 131GLU A 95ARG A 130 | None | 1.41A | 3rqoA-1kexA:0.03rqoB-1kexA:0.0 | 3rqoA-1kexA:15.513rqoB-1kexA:15.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l5j | ACONITATE HYDRATASE2 (Escherichiacoli) |
PF00330(Aconitase)PF06434(Aconitase_2_N)PF11791(Aconitase_B_N) | 4 | TRP A 155PHE A 156GLU A 154ARG A 340 | None | 1.36A | 3rqoA-1l5jA:0.03rqoB-1l5jA:0.0 | 3rqoA-1l5jA:20.213rqoB-1l5jA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nrk | YGFZ PROTEIN (Escherichiacoli) |
PF01571(GCV_T) | 4 | PHE A 154VAL A 200ARG A 160TRP A 27 | SO4 A 400 (-4.6A)NoneNoneSO4 A 400 (-3.4A) | 1.29A | 3rqoA-1nrkA:0.03rqoB-1nrkA:0.0 | 3rqoA-1nrkA:21.243rqoB-1nrkA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d52 | PENTAKETIDE CHROMONESYNTHASE (Aloearborescens) |
PF00195(Chal_sti_synt_N)PF02797(Chal_sti_synt_C) | 4 | PHE A 83GLU A 87VAL A 52ARG A 81 | None | 1.40A | 3rqoA-2d52A:1.03rqoB-2d52A:0.9 | 3rqoA-2d52A:21.893rqoB-2d52A:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d9j | REGULATOR OFG-PROTEIN SIGNALLING7 (Homo sapiens) |
PF00615(RGS) | 4 | PHE A 123GLU A 30VAL A 27TRP A 15 | None | 1.40A | 3rqoA-2d9jA:0.03rqoB-2d9jA:0.0 | 3rqoA-2d9jA:17.603rqoB-2d9jA:17.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2inc | TOLUENE, O-XYLENEMONOOXYGENASEOXYGENASE SUBUNIT (Pseudomonasstutzeri) |
PF02332(Phenol_Hydrox)PF04945(YHS) | 4 | PHE A 29GLU A 27VAL A 23ARG A 116 | None | 1.20A | 3rqoA-2incA:0.03rqoB-2incA:0.0 | 3rqoA-2incA:20.593rqoB-2incA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qqo | NEUROPILIN-2 (Homo sapiens) |
PF00431(CUB)PF00754(F5_F8_type_C) | 4 | TRP A 372PHE A 406GLU A 370ARG A 405 | None | 1.46A | 3rqoA-2qqoA:0.33rqoB-2qqoA:0.0 | 3rqoA-2qqoA:23.533rqoB-2qqoA:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rtt | CHIC (Streptomycescoelicolor) |
PF00553(CBM_2) | 4 | PHE A 41GLU A 38VAL A 37TRP A 22 | None | 1.47A | 3rqoA-2rttA:0.03rqoB-2rttA:0.0 | 3rqoA-2rttA:15.253rqoB-2rttA:15.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ckb | SUSD (Bacteroidesthetaiotaomicron) |
PF07980(SusD_RagB) | 4 | TRP A 485PHE A 489GLU A 484ARG A 437 | None | 0.97A | 3rqoA-3ckbA:0.03rqoB-3ckbA:0.0 | 3rqoA-3ckbA:21.883rqoB-3ckbA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k77 | DNA REPAIR PROTEINXRCC1 (Homo sapiens) |
PF01834(XRCC1_N) | 4 | PHE A 93GLU A 69VAL A 89ARG A 109 | None | 1.49A | 3rqoA-3k77A:undetectable3rqoB-3k77A:undetectable | 3rqoA-3k77A:15.353rqoB-3k77A:15.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lcc | PUTATIVE METHYLCHLORIDE TRANSFERASE (Arabidopsisthaliana) |
PF05724(TPMT) | 4 | PHE A 133GLU A 122VAL A 120ARG A 69 | None | 1.26A | 3rqoA-3lccA:undetectable3rqoB-3lccA:undetectable | 3rqoA-3lccA:18.043rqoB-3lccA:18.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vv4 | METHYL-ACCEPTINGCHEMOTAXIS PROTEIN (Thermosynechococcuselongatus) |
PF01590(GAF) | 4 | PHE A 67GLU A 73VAL A 72TRP A 71 | NoneNoneNonePVG A 201 (-3.6A) | 1.09A | 3rqoA-3vv4A:undetectable3rqoB-3vv4A:undetectable | 3rqoA-3vv4A:19.963rqoB-3vv4A:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cvc | ALCOHOLDEHYDROGENASE (Pseudogluconobactersaccharoketogenes) |
PF13360(PQQ_2) | 4 | TRP A 270PHE A 338ARG A 438TRP A 440 | PQQ A1608 (-3.3A)NoneNonePQQ A1608 (-4.1A) | 1.39A | 3rqoA-4cvcA:undetectable3rqoB-4cvcA:undetectable | 3rqoA-4cvcA:23.323rqoB-4cvcA:23.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j8c | HSC70-INTERACTINGPROTEIN (Rattusnorvegicus) |
no annotation | 4 | PHE A 30GLU A 36VAL A 35TRP A 34 | None | 1.49A | 3rqoA-4j8cA:undetectable3rqoB-4j8cA:undetectable | 3rqoA-4j8cA:8.453rqoB-4j8cA:8.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mh1 | SORBOSEDEHYDROGENASE (Ketogulonicigeniumvulgare) |
PF13360(PQQ_2) | 4 | TRP A 218PHE A 286ARG A 385TRP A 387 | None | 1.35A | 3rqoA-4mh1A:undetectable3rqoB-4mh1A:undetectable | 3rqoA-4mh1A:22.373rqoB-4mh1A:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o6x | ANKYRIN-3 (Homo sapiens) |
PF00531(Death) | 4 | PHE A 28GLU A 25VAL A 71ARG A 58 | None | 1.08A | 3rqoA-4o6xA:undetectable3rqoB-4o6xA:undetectable | 3rqoA-4o6xA:13.543rqoB-4o6xA:13.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qbu | ZMAA (Bacillus cereus) |
PF00698(Acyl_transf_1) | 4 | TRP A 428PHE A 431GLU A 429ARG A 9 | None | 1.47A | 3rqoA-4qbuA:0.73rqoB-4qbuA:undetectable | 3rqoA-4qbuA:21.533rqoB-4qbuA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u3v | POLYKETIDE SYNTHASEPKSR (Bacillussubtilis) |
PF14765(PS-DH) | 4 | TRP A 140PHE A 144GLU A 139VAL A 19 | None | 1.05A | 3rqoA-4u3vA:undetectable3rqoB-4u3vA:undetectable | 3rqoA-4u3vA:19.473rqoB-4u3vA:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cow | PUTATIVEUNCHARACTERIZEDPROTEIN (Caenorhabditisremanei) |
no annotation | 4 | TRP A 407PHE A 404GLU A 410VAL A 409 | None | 1.34A | 3rqoA-5cowA:undetectable3rqoB-5cowA:undetectable | 3rqoA-5cowA:20.903rqoB-5cowA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ft6 | CYSTEINE DESULFURASECSDA (Escherichiacoli) |
PF00266(Aminotran_5) | 4 | TRP A 288PHE A 13GLU A 33VAL A 36 | None | 1.46A | 3rqoA-5ft6A:undetectable3rqoB-5ft6A:undetectable | 3rqoA-5ft6A:21.573rqoB-5ft6A:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jse | PHIAB6 TAILSPIKE (unidentifiedphage) |
PF12708(Pectate_lyase_3) | 4 | TRP A 347PHE A 290VAL A 341TRP A 323 | None | 1.13A | 3rqoA-5jseA:undetectable3rqoB-5jseA:undetectable | 3rqoA-5jseA:19.313rqoB-5jseA:19.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m8t | 5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACIDOXIDASE (Homo sapiens) |
PF00264(Tyrosinase) | 4 | TRP A 414PHE A 411GLU A 413ARG A 225 | None | 1.04A | 3rqoA-5m8tA:undetectable3rqoB-5m8tA:undetectable | 3rqoA-5m8tA:21.753rqoB-5m8tA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5no8 | BACCELL_00875 (Bacteroidescellulosilyticus) |
no annotation | 4 | TRP A 599PHE A 606VAL A 538ARG A 205 | None | 1.46A | 3rqoA-5no8A:undetectable3rqoB-5no8A:undetectable | 3rqoA-5no8A:21.873rqoB-5no8A:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vyo | THIOL:DISULFIDEINTERCHANGE PROTEIN (Burkholderiapseudomallei) |
no annotation | 4 | PHE A 49GLU A 54VAL A 57TRP A 56 | None | 1.00A | 3rqoA-5vyoA:undetectable3rqoB-5vyoA:undetectable | 3rqoA-5vyoA:9.713rqoB-5vyoA:9.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyi | 40S RIBOSOMALPROTEIN S5-B,PUTATIVEUNCHARACTERIZEDPROTEIN (Trichomonasvaginalis) |
PF00177(Ribosomal_S7)PF00333(Ribosomal_S5)PF03719(Ribosomal_S5_C) | 4 | PHE F 50GLU c 51VAL c 16ARG F 49 | NoneNoneNone C 21421 ( 4.4A) | 1.02A | 3rqoA-5xyiF:undetectable3rqoB-5xyiF:undetectable | 3rqoA-5xyiF:18.083rqoB-5xyiF:18.08 |