SIMILAR PATTERNS OF AMINO ACIDS FOR 3ROP_A_NCAA302_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gyc LACCASE 2

(Trametes
versicolor) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 LEU A 185
GLU A 288
TRP A 258
SER A 276
 None
 1.37A 3ropA-1gycA:
undetectable		 3ropA-1gycA:
18.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ism BONE MARROW STROMAL
CELL ANTIGEN 1

(Homo sapiens) 		PF02267
(Rib_hydrolayse) 		4 TRP A  77
LEU A  97
TRP A 140
SER A 144
 NCA  A 303 (-4.4A)
NCA  A 303 (-4.3A)
NCA  A 303 (-4.0A)
NCA  A 303 ( 3.7A)
 0.29A 3ropA-1ismA:
14.6		 3ropA-1ismA:
34.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN

(Escherichia
coli) 		PF01497
(Peripla_BP_2) 		4 TRP N 273
LEU N  44
GLU N  42
TRP N 217
 None
None
ALB  N 500 ( 3.9A)
ALB  N 500 (-3.7A)
 1.37A 3ropA-1k7sN:
undetectable		 3ropA-1k7sN:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kya LACCASE

(Trametes
versicolor) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 LEU A 185
GLU A 288
TRP A 258
SER A 276
 None
 1.45A 3ropA-1kyaA:
undetectable		 3ropA-1kyaA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l2q MONOMETHYLAMINE
METHYLTRANSFERASE

(Methanosarcina
barkeri) 		PF05369
(MtmB) 		4 LEU A 295
GLU A 259
SER A 365
THR A 131
 XPL  A 202 ( 4.8A)
XPL  A 202 (-2.7A)
XPL  A 202 ( 2.7A)
XPL  A 202 ( 4.5A)
 1.29A 3ropA-1l2qA:
undetectable		 3ropA-1l2qA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wkt YEAST KILLER TOXIN

(Cyberlindnera
mrakii) 		PF09207
(Yeast-kill-tox) 		4 GLU A  88
TRP A  24
SER A  42
THR A  39
 None
 1.44A 3ropA-1wktA:
undetectable		 3ropA-1wktA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b92 INTERFERON-INDUCED
GUANYLATE-BINDING
PROTEIN 1

(Homo sapiens) 		PF02263
(GBP)
PF02841
(GBP_C) 		4 LEU A  67
GLU A 251
SER A  52
THR A  75
 LEU  A  67 (-0.6A)
GLU  A 251 ( 0.6A)
SER  A  52 ( 0.0A)
THR  A  75 ( 0.8A)
 1.40A 3ropA-2b92A:
4.0		 3ropA-2b92A:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2eg9 ADP-RIBOSYL CYCLASE
1

(Mus musculus) 		PF02267
(Rib_hydrolayse) 		5 TRP A 129
LEU A 149
GLU A 150
TRP A 193
SER A 197
 None
 0.69A 3ropA-2eg9A:
12.5		 3ropA-2eg9A:
53.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2eg9 ADP-RIBOSYL CYCLASE
1

(Mus musculus) 		PF02267
(Rib_hydrolayse) 		4 TRP A 129
LEU A 149
SER A 197
THR A 225
 None
 0.85A 3ropA-2eg9A:
12.5		 3ropA-2eg9A:
53.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fzv PUTATIVE ARSENICAL
RESISTANCE PROTEIN

(Shigella
flexneri) 		PF03358
(FMN_red) 		4 TRP A 105
LEU A  38
SER A  97
THR A 135
 None
 1.45A 3ropA-2fzvA:
5.5		 3ropA-2fzvA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ivf ETHYLBENZENE
DEHYDROGENASE
ALPHA-SUBUNIT

(Aromatoleum
aromaticum) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		4 LEU A 543
TRP A 200
SER A 214
THR A 207
 None
 1.31A 3ropA-2ivfA:
2.5		 3ropA-2ivfA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q62 ARSH

(Sinorhizobium
meliloti) 		PF03358
(FMN_red) 		4 TRP A 104
LEU A  38
SER A  96
THR A 134
 None
 1.48A 3ropA-2q62A:
3.2		 3ropA-2q62A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qt6 LACCASE

(Lentinus
tigrinus) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 LEU A 185
GLU A 288
TRP A 258
SER A 276
 None
 1.44A 3ropA-2qt6A:
undetectable		 3ropA-2qt6A:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vhh CG3027-PA

(Drosophila
melanogaster) 		PF00795
(CN_hydrolase) 		4 LEU A 268
GLU A 272
SER A 265
THR A 260
 None
 1.12A 3ropA-2vhhA:
undetectable		 3ropA-2vhhA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xyb LACCASE

(Trametes
cinnabarina) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 LEU A 185
GLU A 288
TRP A 258
SER A 276
 None
 1.42A 3ropA-2xybA:
undetectable		 3ropA-2xybA:
19.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3gc6 ECTO-NAD+
GLYCOHYDROLASE (CD38
MOLECULE)

(Bos taurus) 		PF02267
(Rib_hydrolayse) 		5 TRP A 118
LEU A 137
GLU A 138
TRP A 181
SER A 185
 None
 0.29A 3ropA-3gc6A:
30.6		 3ropA-3gc6A:
45.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3i9k ADP-RIBOSYL CYCLASE

(Aplysia
californica) 		PF02267
(Rib_hydrolayse) 		5 TRP A  77
LEU A  97
GLU A  98
TRP A 140
SER A 144
 None
 0.36A 3ropA-3i9kA:
25.3		 3ropA-3i9kA:
32.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kvy URIDINE
PHOSPHORYLASE

(Bos taurus) 		PF01048
(PNP_UDP_1) 		4 LEU A 196
GLU A 198
SER A 193
THR A 201
 None
 1.49A 3ropA-3kvyA:
2.2		 3ropA-3kvyA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l0g NICOTINATE-NUCLEOTID
E PYROPHOSPHORYLASE

(Ehrlichia
chaffeensis) 		PF01729
(QRPTase_C)
PF02749
(QRPTase_N) 		4 LEU A 211
GLU A 192
SER A 236
THR A 129
 None
None
EDO  A 300 ( 4.6A)
EDO  A 300 (-4.2A)
 1.49A 3ropA-3l0gA:
undetectable		 3ropA-3l0gA:
21.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3p5s CD38 MOLECULE

(Bos taurus) 		PF02267
(Rib_hydrolayse) 		5 TRP A 118
LEU A 137
GLU A 138
TRP A 181
SER A 185
 AVU  A 280 (-3.8A)
AVU  A 280 (-3.7A)
AVU  A 280 (-3.3A)
AVU  A 280 (-3.6A)
AVU  A 280 (-2.9A)
 0.35A 3ropA-3p5sA:
30.4		 3ropA-3p5sA:
41.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pxl LACCASE

(Trametes
hirsuta) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 LEU A 185
GLU A 288
TRP A 258
SER A 276
 None
 1.43A 3ropA-3pxlA:
undetectable		 3ropA-3pxlA:
19.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3rom ADP-RIBOSYL CYCLASE
1

(Homo sapiens) 		PF02267
(Rib_hydrolayse) 		6 TRP A 125
LEU A 145
GLU A 146
TRP A 189
SER A 193
THR A 221
 48Z  A 301 (-3.6A)
48Z  A 301 ( 4.8A)
48Z  A 301 ( 4.3A)
None
48Z  A 301 (-2.8A)
48Z  A 301 (-4.0A)
 0.54A 3ropA-3romA:
38.6		 3ropA-3romA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3so4 METHIONINE-ADENOSYLT
RANSFERASE

(Entamoeba
histolytica) 		PF00438
(S-AdoMet_synt_N)
PF02772
(S-AdoMet_synt_M)
PF02773
(S-AdoMet_synt_C) 		4 TRP A 261
LEU A 139
SER A 133
THR A 130
 None
 1.50A 3ropA-3so4A:
undetectable		 3ropA-3so4A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uow GMP SYNTHETASE

(Plasmodium
falciparum) 		PF00117
(GATase)
PF00958
(GMP_synt_C)
PF02540
(NAD_synthase) 		4 TRP A 167
GLU A 213
SER A 508
THR A 512
 None
 1.47A 3ropA-3uowA:
2.9		 3ropA-3uowA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wz1 AGARASE

(Microbulbifer
thermotolerans) 		PF00722
(Glyco_hydro_16) 		4 TRP A 138
GLU A 257
SER A 109
THR A 111
 None
 1.28A 3ropA-3wz1A:
undetectable		 3ropA-3wz1A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x1b LACCASE

(Lentinus) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 LEU A 206
GLU A 309
TRP A 279
SER A 297
 None
 1.31A 3ropA-3x1bA:
undetectable		 3ropA-3x1bA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyv AOX3

(Mus musculus) 		PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C) 		4 LEU A 812
GLU A 656
SER A 808
THR A 914
 None
 1.42A 3ropA-3zyvA:
undetectable		 3ropA-3zyvA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fuk METHIONINE
AMINOPEPTIDASE

(Trypanosoma
brucei) 		PF00557
(Peptidase_M24) 		4 TRP A 365
LEU A 141
GLU A 225
THR A 363
 None
 1.09A 3ropA-4fukA:
undetectable		 3ropA-4fukA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h7n ALDEHYDE
DEHYDROGENASE

(Trichormus
variabilis) 		PF00171
(Aldedh) 		4 LEU A 389
GLU A 229
SER A 390
THR A 421
 None
 1.45A 3ropA-4h7nA:
undetectable		 3ropA-4h7nA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hn0 PUTATIVE 3-EPIMERASE
IN D-ALLOSE PATHWAY

(Streptomyces
bikiniensis) 		PF00908
(dTDP_sugar_isom) 		4 LEU A   4
GLU A  97
SER A  11
THR A 107
 None
 1.38A 3ropA-4hn0A:
undetectable		 3ropA-4hn0A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i9a QUINOLINATE
PHOSPHORIBOSYLTRANSF
ERASE

(Sus scrofa) 		PF01729
(QRPTase_C)
PF02749
(QRPTase_N) 		4 LEU A 220
GLU A 199
SER A 248
THR A 137
 None
None
NCN  A 301 (-2.9A)
NCN  A 301 ( 4.4A)
 1.41A 3ropA-4i9aA:
2.1		 3ropA-4i9aA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jhv LACCASE

(Coriolopsis
caperata) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 LEU A 184
GLU A 287
TRP A 257
SER A 275
 None
 1.42A 3ropA-4jhvA:
undetectable		 3ropA-4jhvA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r94 NON-STRUCTURAL
PROTEIN NS1

(Rodent
protoparvovirus
1) 		PF12433
(PV_NSP1) 		4 LEU A  56
GLU A  53
TRP A 156
SER A  92
 None
 1.41A 3ropA-4r94A:
undetectable		 3ropA-4r94A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE

(uncultured
bacterium) 		PF00150
(Cellulase) 		4 TRP A 200
LEU A 159
GLU A 214
THR A 193
 None
 1.34A 3ropA-4w87A:
undetectable		 3ropA-4w87A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wxp NS3-4 PROTEASE

(Hepacivirus C) 		PF07652
(Flavi_DEAD) 		4 TRP A 582
LEU A 585
SER A 584
THR A 550
 None
 1.18A 3ropA-4wxpA:
2.1		 3ropA-4wxpA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zi8 PROTEIN PCDHGC3

(Mus musculus) 		PF00028
(Cadherin)
PF08266
(Cadherin_2) 		4 LEU A 187
GLU A 143
SER A 195
THR A 197
 None
 1.43A 3ropA-4zi8A:
undetectable		 3ropA-4zi8A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM

(Escherichia
coli) 		PF00207
(A2M)
PF01835
(A2M_N)
PF07703
(A2M_N_2)
PF11974
(MG1) 		4 TRP A 915
GLU A 855
SER A 625
THR A 634
 None
 1.46A 3ropA-5a42A:
undetectable		 3ropA-5a42A:
9.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5bni UNCHARACTERIZED
PROTEIN

(Sus scrofa) 		PF02267
(Rib_hydrolayse) 		5 LEU A 150
GLU A 151
TRP A 193
SER A 197
THR A 225
 None
 0.70A 3ropA-5bniA:
30.0		 3ropA-5bniA:
55.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ehf LACCASE

(Antrodiella
faginea) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 LEU A 186
GLU A 290
TRP A 259
SER A 278
 None
 1.46A 3ropA-5ehfA:
undetectable		 3ropA-5ehfA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ex2 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Hirschia
baltica) 		PF00160
(Pro_isomerase) 		4 LEU A 190
GLU A  36
SER A 259
THR A 257
 None
 1.43A 3ropA-5ex2A:
undetectable		 3ropA-5ex2A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f8z PLASMA KALLIKREIN
LIGHT CHAIN

(Homo sapiens) 		PF00089
(Trypsin) 		4 TRP A 141
LEU A  71
SER A  22
THR A 139
 None
SO4  A 302 (-3.0A)
None
None
 1.31A 3ropA-5f8zA:
undetectable		 3ropA-5f8zA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fg3 PROBABLE TRANSLATION
INITIATION FACTOR
IF-2

(Aeropyrum
pernix) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF11987
(IF-2)
PF14578
(GTP_EFTU_D4) 		4 LEU A 128
GLU A 124
SER A  95
THR A 375
 None
 1.48A 3ropA-5fg3A:
4.3		 3ropA-5fg3A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gsl 778AA LONG
HYPOTHETICAL
BETA-GALACTOSIDASE

(Pyrococcus
horikoshii) 		PF02449
(Glyco_hydro_42) 		4 LEU A 354
GLU A 105
TRP A 400
SER A 353
 None
PO4  A 802 (-2.8A)
None
None
 1.07A 3ropA-5gslA:
2.2		 3ropA-5gslA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gsm EXO-BETA-D-GLUCOSAMI
NIDASE

(Thermococcus
kodakarensis) 		PF02449
(Glyco_hydro_42) 		4 LEU A 352
GLU A 103
TRP A 398
SER A 351
 GCS  A 801 (-4.9A)
GCS  A 801 (-2.9A)
None
None
 1.07A 3ropA-5gsmA:
2.5		 3ropA-5gsmA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j0b MYELOID CELL SURFACE
ANTIGEN CD33

(Homo sapiens) 		PF00047
(ig)
PF07686
(V-set) 		4 LEU A 210
TRP A 179
SER A 181
THR A 185
 None
 1.26A 3ropA-5j0bA:
undetectable		 3ropA-5j0bA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l35 GENE 5 PROTEIN

(Shigella virus
Sf6) 		PF11651
(P22_CoatProtein) 		4 TRP A 275
LEU A 276
SER A 330
THR A 273
 None
 1.41A 3ropA-5l35A:
undetectable		 3ropA-5l35A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n81 TYROCIDINE SYNTHASE
1

(Brevibacillus
parabrevis) 		no annotation 4 TRP A 311
LEU A 307
SER A 303
THR A 298
 None
 1.44A 3ropA-5n81A:
2.8		 3ropA-5n81A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ueb NEGOA.19184.A

(Neisseria
gonorrhoeae) 		PF14085
(DUF4265) 		4 LEU A  38
GLU A  19
SER A 104
THR A  71
 None
 0.95A 3ropA-5uebA:
undetectable		 3ropA-5uebA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus musculus;
Rattus
norvegicus) 		PF00060
(Lig_chan)
PF01094
(ANF_receptor)
PF07803
(GSG-1)
PF10613
(Lig_chan-Glu_bd) 		4 LEU A 122
GLU A 126
TRP A 158
SER A 152
 None
 1.47A 3ropA-5welA:
undetectable		 3ropA-5welA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6exn PRE-MRNA-SPLICING
FACTOR CLF1

(Saccharomyces
cerevisiae) 		no annotation 4 LEU S  92
GLU S  89
SER S  96
THR S 128
 None
 1.24A 3ropA-6exnS:
undetectable		 3ropA-6exnS:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gk6 -

(-) 		no annotation 4 LEU A 258
GLU A 287
SER A 261
THR A 384
 None
 1.47A 3ropA-6gk6A:
undetectable		 3ropA-6gk6A:
undetectable