SIMILAR PATTERNS OF AMINO ACIDS FOR 3REM_B_SALB301_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1al8 GLYCOLATE OXIDASE

(Spinacia
oleracea) 		PF01070
(FMN_dh) 		4 VAL A 294
ARG A 290
VAL A   6
ILE A 307
 None
 0.99A 3remB-1al8A:
undetectable		 3remB-1al8A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cp9 PENICILLIN G AMIDASE

(Providencia
rettgeri) 		PF01804
(Penicil_amidase) 		4 VAL A 132
VAL B 155
TYR A  94
ILE A  90
 None
 0.89A 3remB-1cp9A:
undetectable		 3remB-1cp9A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hg8 ENDOPOLYGALACTURONAS
E

(Fusarium
verticillioides) 		PF00295
(Glyco_hydro_28) 		4 VAL A 315
VAL A 281
ILE A 268
GLN A 300
 None
 1.01A 3remB-1hg8A:
undetectable		 3remB-1hg8A:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ia5 POLYGALACTURONASE

(Aspergillus
aculeatus) 		PF00295
(Glyco_hydro_28) 		4 VAL A 281
VAL A 249
ILE A 236
GLN A 268
 None
 0.93A 3remB-1ia5A:
undetectable		 3remB-1ia5A:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k9x M32 CARBOXYPEPTIDASE

(Pyrococcus
furiosus) 		PF02074
(Peptidase_M32) 		4 VAL A 338
VAL A 215
TYR A 320
ILE A 319
 None
 1.02A 3remB-1k9xA:
undetectable		 3remB-1k9xA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m7h ADENYLYLSULFATE
KINASE

(Penicillium
chrysogenum) 		PF01583
(APS_kinase) 		4 VAL A 134
VAL A 182
TYR A 199
ILE A 196
 None
 0.98A 3remB-1m7hA:
undetectable		 3remB-1m7hA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mc8 FLAP ENDONUCLEASE-1

(Pyrococcus
horikoshii) 		PF00752
(XPG_N)
PF00867
(XPG_I) 		4 ARG A  88
VAL A 270
TYR A 273
ILE A 275
 None
 1.02A 3remB-1mc8A:
undetectable		 3remB-1mc8A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p99 HYPOTHETICAL PROTEIN
PG110

(Staphylococcus
aureus) 		PF03180
(Lipoprotein_9) 		4 VAL A 240
VAL A  67
TYR A 259
ILE A 255
 None
 1.00A 3remB-1p99A:
undetectable		 3remB-1p99A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ps9 2,4-DIENOYL-COA
REDUCTASE

(Escherichia
coli) 		PF00724
(Oxidored_FMN)
PF07992
(Pyr_redox_2) 		4 VAL A 284
TYR A 213
ILE A 212
GLN A 100
 None
None
None
FMN  A 702 (-2.8A)
 1.00A 3remB-1ps9A:
undetectable		 3remB-1ps9A:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1psy 2S ALBUMIN

(Ricinus
communis) 		PF00234
(Tryp_alpha_amyl) 		4 ARG A  19
VAL A  22
TYR A  84
ILE A  82
 None
 1.03A 3remB-1psyA:
2.1		 3remB-1psyA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qdn PROTEIN
(N-ETHYLMALEIMIDE
SENSITIVE FUSION
PROTEIN (NSF))

(Cricetulus
griseus) 		PF02359
(CDC48_N)
PF02933
(CDC48_2) 		4 ARG A   4
VAL A  80
MET A   6
GLN A  33
 None
 0.78A 3remB-1qdnA:
undetectable		 3remB-1qdnA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r3n BETA-ALANINE
SYNTHASE

(Lachancea
kluyveri) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 ARG A  74
VAL A  90
TYR A 206
ILE A 207
 None
 0.96A 3remB-1r3nA:
undetectable		 3remB-1r3nA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ry2 ACETYL-COENZYME A
SYNTHETASE 1

(Saccharomyces
cerevisiae) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
PF16177
(ACAS_N) 		4 VAL A 176
VAL A 194
MET A 196
ILE A 209
 None
 0.83A 3remB-1ry2A:
undetectable		 3remB-1ry2A:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s4k PUTATIVE CYTOPLASMIC
PROTEIN YDIL

(Salmonella
enterica) 		PF08965
(DUF1870) 		4 ARG A  58
TYR A  24
ILE A  25
GLN A  27
 None
 1.00A 3remB-1s4kA:
3.0		 3remB-1s4kA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos taurus) 		PF00080
(Sod_Cu) 		4 VAL A  79
VAL A  27
TYR A 108
ILE A 110
 None
 0.96A 3remB-1sxzA:
undetectable		 3remB-1sxzA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vd2 PROTEIN KINASE C,
IOTA TYPE

(Homo sapiens) 		PF00564
(PB1) 		4 VAL A  45
MET A  48
TYR A  22
ILE A  94
 None
 0.89A 3remB-1vd2A:
undetectable		 3remB-1vd2A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yif BETA-1,4-XYLOSIDASE

(Bacillus
subtilis) 		PF04616
(Glyco_hydro_43) 		4 VAL A 252
VAL A   7
TYR A  24
ILE A  26
 None
 1.01A 3remB-1yifA:
undetectable		 3remB-1yifA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a4a DEOXYRIBOSE-PHOSPHAT
E ALDOLASE

(Plasmodium
yoelii) 		PF01791
(DeoC) 		4 VAL A 211
VAL A  13
TYR A 224
ILE A 225
 None
 0.96A 3remB-2a4aA:
undetectable		 3remB-2a4aA:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aeg HYPOTHETICAL PROTEIN
AGR_PAT_140

(Agrobacterium
fabrum) 		PF02586
(SRAP) 		4 VAL A 120
VAL A 100
TYR A 179
ILE A 158
 None
 1.02A 3remB-2aegA:
undetectable		 3remB-2aegA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d8d PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE/CHORISMATE
MUTASE

(Thermus
thermophilus) 		PF01817
(CM_2) 		4 ARG A  26
VAL A  30
ARG A  49
MET A  53
 None
None
CL  A  91 (-4.0A)
CL  A  91 ( 4.2A)
 0.84A 3remB-2d8dA:
9.0		 3remB-2d8dA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ds7 ATP-DEPENDENT CLP
PROTEASE ATP-BINDING
SUBUNIT CLPX

(Escherichia
coli) 		PF06689
(zf-C4_ClpX) 		4 VAL A  33
VAL A  40
MET A  43
ILE A  28
 None
 0.91A 3remB-2ds7A:
undetectable		 3remB-2ds7A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f1f ACETOLACTATE
SYNTHASE ISOZYME III
SMALL SUBUNIT

(Escherichia
coli) 		PF10369
(ALS_ss_C)
PF13710
(ACT_5) 		4 VAL A 152
ARG A  45
VAL A   7
ILE A  48
 None
 1.01A 3remB-2f1fA:
undetectable		 3remB-2f1fA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fe8 REPLICASE
POLYPROTEIN 1AB

(Severe acute
respiratory
syndrome-related
coronavirus) 		PF08715
(Viral_protease) 		5 VAL A 189
VAL A 185
TYR A 234
ILE A 315
GLN A 195
 None
 1.36A 3remB-2fe8A:
undetectable		 3remB-2fe8A:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gca FOLYLPOLYGLUTAMATE
SYNTHASE

(Lactobacillus
casei) 		PF02875
(Mur_ligase_C)
PF08245
(Mur_ligase_M) 		4 VAL A 139
VAL A 162
TYR A 275
ILE A  57
 None
 1.05A 3remB-2gcaA:
undetectable		 3remB-2gcaA:
13.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2h9c SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB

(Pseudomonas
aeruginosa) 		PF01817
(CM_2) 		5 ARG A  31
VAL A  54
MET A  57
ILE A  87
GLN A  90
 NO3  A 100 (-2.8A)
None
NO3  A 100 (-3.5A)
None
None
 0.61A 3remB-2h9cA:
12.6		 3remB-2h9cA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iir ACETATE KINASE

(Thermotoga
maritima) 		PF00871
(Acetate_kinase) 		4 VAL A 214
VAL A 343
TYR A 312
ILE A 313
 None
 1.04A 3remB-2iirA:
undetectable		 3remB-2iirA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ime 2-HYDROXYCHROMENE-2-
CARBOXYLATE
ISOMERASE

(Pseudomonas
putida) 		PF01323
(DSBA) 		4 ARG A 163
VAL A 165
ILE A  37
GLN A 156
 None
 0.96A 3remB-2imeA:
undetectable		 3remB-2imeA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iq7 ENDOPOLYGALACTURONAS
E

(Colletotrichum
lupini) 		PF00295
(Glyco_hydro_28) 		4 VAL A 302
VAL A 268
ILE A 255
GLN A 287
 None
 0.96A 3remB-2iq7A:
undetectable		 3remB-2iq7A:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mp1 C-C MOTIF CHEMOKINE
19

(Homo sapiens) 		PF00048
(IL8) 		4 ARG A  64
ARG A  23
TYR A  20
ILE A  21
 None
 0.96A 3remB-2mp1A:
undetectable		 3remB-2mp1A:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r0q PUTATIVE TRANSPOSON
TN552 DNA-INVERTASE
BIN3

(Staphylococcus
aureus) 		PF00239
(Resolvase)
PF02796
(HTH_7) 		4 ARG C 167
VAL C 168
MET C 171
ILE C 187
 None
 0.74A 3remB-2r0qC:
undetectable		 3remB-2r0qC:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44

(Saccharomyces
cerevisiae) 		PF00773
(RNB)
PF17215
(Rrp44_S1)
PF17216
(Rrp44_CSD1) 		4 ARG D 971
VAL D 973
VAL D 981
ILE D 939
 None
 1.05A 3remB-2vnuD:
undetectable		 3remB-2vnuD:
8.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vsq SURFACTIN SYNTHETASE
SUBUNIT 3

(Bacillus
subtilis) 		PF00501
(AMP-binding)
PF00550
(PP-binding)
PF00668
(Condensation)
PF00975
(Thioesterase)
PF13193
(AMP-binding_C) 		4 ARG A  77
TYR A  14
ILE A 187
GLN A  80
 None
 1.04A 3remB-2vsqA:
undetectable		 3remB-2vsqA:
6.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vvq RIBOSE-5-PHOSPHATE
ISOMERASE B

(Mycobacterium
tuberculosis) 		PF02502
(LacAB_rpiB) 		4 ARG A 100
VAL A 128
TYR A   7
ILE A  66
 None
 1.04A 3remB-2vvqA:
undetectable		 3remB-2vvqA:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wy4 SINGLE DOMAIN
HAEMOGLOBIN

(Campylobacter
jejuni) 		PF00042
(Globin) 		4 VAL A  38
MET A  41
TYR A  94
ILE A  96
 HEM  A 150 ( 4.9A)
HEM  A 150 (-4.0A)
HEM  A 150 (-3.6A)
None
 0.69A 3remB-2wy4A:
3.9		 3remB-2wy4A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y7c GENE 0.3 PROTEIN

(Escherichia
virus T7) 		PF08684
(ocr) 		4 VAL D   6
TYR D  82
ILE D  81
GLN D  78
 None
 1.05A 3remB-2y7cD:
2.3		 3remB-2y7cD:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y8u CHITIN DEACETYLASE

(Aspergillus
nidulans) 		PF01522
(Polysacc_deac_1) 		4 ARG A  88
VAL A 129
TYR A 236
ILE A 233
 None
 1.02A 3remB-2y8uA:
undetectable		 3remB-2y8uA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z36 CYTOCHROME P450 TYPE
COMPACTIN
3'',4''-HYDROXYLASE

(Nonomuraea
recticatena) 		PF00067
(p450) 		4 ARG A  18
VAL A 295
TYR A 398
ILE A 397
 None
MES  A4574 ( 4.0A)
None
None
 0.97A 3remB-2z36A:
1.4		 3remB-2z36A:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b70 ENOYL REDUCTASE

(Aspergillus
terreus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 ARG A  89
VAL A  90
ILE A  84
GLN A  85
 None
 1.01A 3remB-3b70A:
undetectable		 3remB-3b70A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cr7 ADENYLYL-SULFATE
KINASE

(Penicillium
chrysogenum) 		PF01583
(APS_kinase) 		4 VAL A 134
VAL A 182
TYR A 199
ILE A 196
 None
 0.93A 3remB-3cr7A:
undetectable		 3remB-3cr7A:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fkd L-THREONINE-O-3-PHOS
PHATE DECARBOXYLASE

(Porphyromonas
gingivalis) 		PF00155
(Aminotran_1_2) 		4 VAL A 192
TYR A  81
ILE A  83
GLN A  82
 None
 0.99A 3remB-3fkdA:
undetectable		 3remB-3fkdA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ip1 ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING

(Thermotoga
maritima) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 VAL A 390
VAL A   4
TYR A 377
ILE A 378
 None
 0.78A 3remB-3ip1A:
undetectable		 3remB-3ip1A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k6q PUTATIVE LIGAND
BINDING PROTEIN

(Syntrophomonas
wolfei) 		PF12910
(PHD_like) 		4 ARG A  22
VAL A  21
TYR A  16
ILE A  17
 None
 1.00A 3remB-3k6qA:
undetectable		 3remB-3k6qA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kio RIBONUCLEASE H2
SUBUNIT A

(Mus musculus) 		PF01351
(RNase_HII) 		4 VAL A 136
TYR A 128
ILE A 126
GLN A 127
 None
 0.87A 3remB-3kioA:
undetectable		 3remB-3kioA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kzp PUTATIVE DIGUANYLATE
CYCLASE/PHOSPHODIEST
ERASE

(Listeria
monocytogenes) 		PF00563
(EAL) 		4 ARG A 158
VAL A 159
TYR A 165
ILE A 166
 None
 0.98A 3remB-3kzpA:
undetectable		 3remB-3kzpA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lr1 TUNGSTATE ABC
TRANSPORTER,
PERIPLASMIC
TUNGSTATE-BINDING
PROTEIN

(Geobacter
sulfurreducens) 		PF12849
(PBP_like_2) 		4 VAL A  54
MET A   6
TYR A 220
ILE A 218
 None
 0.99A 3remB-3lr1A:
undetectable		 3remB-3lr1A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mr1 METHIONINE
AMINOPEPTIDASE

(Rickettsia
prowazekii) 		PF00557
(Peptidase_M24) 		4 ARG A 163
VAL A 161
TYR A 148
ILE A 150
 None
 1.03A 3remB-3mr1A:
undetectable		 3remB-3mr1A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n6r PROPIONYL-COA
CARBOXYLASE, ALPHA
SUBUNIT

(Ruegeria
pomeroyi) 		PF00289
(Biotin_carb_N)
PF00364
(Biotin_lipoyl)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		4 ARG A  71
VAL A 435
TYR A 445
ILE A 441
 None
 0.98A 3remB-3n6rA:
undetectable		 3remB-3n6rA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3neu LIN1836 PROTEIN

(Listeria
innocua) 		PF00392
(GntR) 		4 VAL A  46
TYR A  12
ILE A  15
GLN A  14
 None
 1.04A 3remB-3neuA:
undetectable		 3remB-3neuA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p56 RIBONUCLEASE H2
SUBUNIT A

(Homo sapiens) 		PF01351
(RNase_HII) 		4 VAL A 135
TYR A 127
ILE A 125
GLN A 126
 None
 0.98A 3remB-3p56A:
undetectable		 3remB-3p56A:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pko GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE

(Lactobacillus
brevis) 		PF00348
(polyprenyl_synt) 		4 VAL A  89
ARG A  96
ILE A 102
GLN A 103
 None
CIT  A 326 ( 4.8A)
None
None
 0.92A 3remB-3pkoA:
1.2		 3remB-3pkoA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q75 FARNESYLTRANSFERASE
BETA SUBUNIT

(Cryptococcus
neoformans) 		PF00432
(Prenyltrans) 		4 VAL B 448
VAL B 205
TYR B 173
ILE B 172
 None
 0.94A 3remB-3q75B:
undetectable		 3remB-3q75B:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qq8 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE

(Homo sapiens) 		PF02359
(CDC48_N)
PF02933
(CDC48_2) 		4 VAL A  39
ARG A  89
VAL A  94
ILE A 100
 None
 1.02A 3remB-3qq8A:
undetectable		 3remB-3qq8A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r2e DIHYDRONEOPTERIN
ALDOLASE

(Yersinia pestis) 		PF02152
(FolB) 		4 ARG A  74
VAL A  75
ILE A  15
GLN A  22
 None
 1.02A 3remB-3r2eA:
undetectable		 3remB-3r2eA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r8e HYPOTHETICAL SUGAR
KINASE

(Cytophaga
hutchinsonii) 		PF00480
(ROK) 		4 VAL A 237
VAL A 158
MET A 161
ILE A 129
 None
 0.97A 3remB-3r8eA:
undetectable		 3remB-3r8eA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rio PTSGHI OPERON
ANTITERMINATOR

(Bacillus
subtilis) 		PF00874
(PRD)
PF03123
(CAT_RBD) 		4 VAL A 140
MET A 143
TYR A  83
ILE A  85
 None
 0.90A 3remB-3rioA:
undetectable		 3remB-3rioA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rlf MALTOSE/MALTODEXTRIN
IMPORT ATP-BINDING
PROTEIN MALK

(Escherichia
coli) 		PF00005
(ABC_tran)
PF08402
(TOBE_2) 		4 ARG A 286
VAL A 230
TYR A 222
GLN A 194
 None
 1.00A 3remB-3rlfA:
undetectable		 3remB-3rlfA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dwq TRNA-SPLICING LIGASE
RTCB

(Pyrococcus
horikoshii) 		PF01139
(RtcB) 		4 VAL A 324
VAL A 210
MET A 473
TYR A 222
 None
 0.85A 3remB-4dwqA:
undetectable		 3remB-4dwqA:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fj6 GLYCOSIDE HYDROLASE
FAMILY 33, CANDIDATE
SIALIDASE

(Parabacteroides
distasonis) 		PF13859
(BNR_3)
PF14873
(BNR_assoc_N) 		4 VAL A 283
VAL A 333
ILE A 360
GLN A 343
 None
 1.02A 3remB-4fj6A:
undetectable		 3remB-4fj6A:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g59 M152 PROTEIN

(Murid
betaherpesvirus
1) 		PF11624
(M157) 		4 VAL C  86
ARG C  91
VAL C  93
MET C 112
 None
 1.01A 3remB-4g59C:
undetectable		 3remB-4g59C:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hr7 BIOTIN CARBOXYL
CARRIER PROTEIN OF
ACETYL-COA
CARBOXYLASE

(Escherichia
coli) 		PF00364
(Biotin_lipoyl) 		4 VAL B 146
ARG B  84
VAL B  83
ILE B 127
 None
 1.03A 3remB-4hr7B:
undetectable		 3remB-4hr7B:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hw6 HYPOTHETICAL
PROTEIN, IPT/TIG
DOMAIN PROTEIN

(Bacteroides
ovatus) 		PF01833
(TIG) 		4 VAL A 375
VAL A 399
TYR A 441
ILE A 439
 None
 0.93A 3remB-4hw6A:
undetectable		 3remB-4hw6A:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i70 INOSINE-ADENOSINE-GU
ANOSINE-NUCLEOSIDE
HYDROLASE

(Trypanosoma
brucei) 		PF01156
(IU_nuc_hydro) 		4 VAL A 174
ARG A 293
TYR A 188
ILE A 187
 None
 0.81A 3remB-4i70A:
undetectable		 3remB-4i70A:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j01 TRANSCRIPTION FACTOR
HETR

(Fischerella
thermalis) 		PF03574
(Peptidase_S48) 		4 VAL A  82
VAL A  75
TYR A  51
ILE A  50
 None
 0.89A 3remB-4j01A:
undetectable		 3remB-4j01A:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kpu ELECTRON TRANSFER
FLAVOPROTEIN ALPHA
SUBUNIT

(Acidaminococcus
fermentans) 		PF00766
(ETF_alpha)
PF01012
(ETF) 		4 VAL A 104
TYR A  99
ILE A  96
GLN A 100
 None
 0.97A 3remB-4kpuA:
undetectable		 3remB-4kpuA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lbw ELONGATION FACTOR
TU-A

(Thermus
thermophilus) 		PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3)
PF03144
(GTP_EFTU_D2) 		4 ARG A   7
VAL A 286
MET A 272
ILE A 242
 None
 1.02A 3remB-4lbwA:
undetectable		 3remB-4lbwA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lvr INTRAFLAGELLAR
TRANSPORT PROTEIN 81

(Chlamydomonas
reinhardtii) 		no annotation 4 VAL A  88
TYR A  97
ILE A  99
GLN A  98
 None
 0.96A 3remB-4lvrA:
undetectable		 3remB-4lvrA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m5t ALPHA-CRYSTALLIN B
CHAIN

(Homo sapiens) 		PF00011
(HSP20) 		4 VAL A  77
VAL A  93
TYR A 122
ILE A 124
 None
 0.99A 3remB-4m5tA:
undetectable		 3remB-4m5tA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n8g TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT

(Chromohalobacter
salexigens) 		PF03480
(DctP) 		4 VAL A 229
VAL A 210
TYR A 203
GLN A 230
 None
 1.01A 3remB-4n8gA:
undetectable		 3remB-4n8gA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nen INTEGRIN ALPHA-X

(Homo sapiens) 		PF00092
(VWA)
PF01839
(FG-GAP)
PF08441
(Integrin_alpha2) 		4 VAL A 905
VAL A 938
ILE A1053
GLN A1062
 None
 0.94A 3remB-4nenA:
undetectable		 3remB-4nenA:
6.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ngu TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT

(Desulfovibrio
alaskensis) 		PF03480
(DctP) 		4 VAL A 232
VAL A 213
TYR A 206
GLN A 233
 None
 1.01A 3remB-4nguA:
undetectable		 3remB-4nguA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nn3 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT

(Desulfovibrio
salexigens) 		PF03480
(DctP) 		4 VAL A 225
VAL A 206
TYR A 199
GLN A 226
 None
 1.05A 3remB-4nn3A:
undetectable		 3remB-4nn3A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ovs TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT

(Sulfurospirillum
deleyianum) 		PF03480
(DctP) 		4 VAL A 220
VAL A 201
TYR A 194
GLN A 221
 None
 0.99A 3remB-4ovsA:
undetectable		 3remB-4ovsA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q2c CRISPR-ASSOCIATED
HELICASE CAS3

(Thermobaculum
terrenum) 		PF00271
(Helicase_C) 		4 VAL A 600
ARG A 637
VAL A 884
ILE A 939
 None
 1.04A 3remB-4q2cA:
undetectable		 3remB-4q2cA:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6k BNR/ASP-BOX REPEAT
PROTEIN

(Bacteroides
caccae) 		PF13088
(BNR_2)
PF14873
(BNR_assoc_N) 		4 VAL A 145
ARG A 143
VAL A  84
ILE A  89
 None
 1.00A 3remB-4q6kA:
undetectable		 3remB-4q6kA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6k BNR/ASP-BOX REPEAT
PROTEIN

(Bacteroides
caccae) 		PF13088
(BNR_2)
PF14873
(BNR_assoc_N) 		4 VAL A 303
VAL A 353
ILE A 380
GLN A 363
 None
 0.99A 3remB-4q6kA:
undetectable		 3remB-4q6kA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qns HISTONE
ACETYLTRANSFERASE
GCN5, PUTATIVE

(Plasmodium
falciparum) 		PF00439
(Bromodomain) 		4 MET A1406
TYR A1457
ILE A1453
GLN A1450
 None
SO4  A1501 (-4.9A)
None
None
 0.92A 3remB-4qnsA:
undetectable		 3remB-4qnsA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4up3 THIOREDOXIN
REDUCTASE

(Entamoeba
histolytica) 		PF07992
(Pyr_redox_2) 		4 ARG A 288
TYR A 266
ILE A 267
GLN A 286
 None
 1.05A 3remB-4up3A:
undetectable		 3remB-4up3A:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wu0 SIMILAR TO YTER
(BACILUS SUBTILIS)

(Clostridium
acetobutylicum) 		PF07470
(Glyco_hydro_88) 		4 ARG A 103
VAL A 143
ILE A 155
GLN A 158
 None
 1.03A 3remB-4wu0A:
undetectable		 3remB-4wu0A:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5awn HEAVY CHAIN OF
3BC176 FAB

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 ARG H  94
VAL H   2
TYR H  27
GLN H   1
 None
 0.91A 3remB-5awnH:
undetectable		 3remB-5awnH:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b1r B-CELL
DIFFERENTIATION
ANTIGEN CD72

(Mus musculus) 		no annotation 4 ARG A 242
VAL A 280
ILE A 298
GLN A 299
 None
None
None
GOL  A 402 ( 4.7A)
 0.98A 3remB-5b1rA:
undetectable		 3remB-5b1rA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d4w PUTATIVE HEAT SHOCK
PROTEIN

(Chaetomium
thermophilum) 		PF00004
(AAA)
PF07724
(AAA_2)
PF10431
(ClpB_D2-small) 		4 VAL A 561
ARG A 423
VAL A 421
GLN A 565
 None
 0.99A 3remB-5d4wA:
undetectable		 3remB-5d4wA:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dp2 CURF

(Lyngbya
majuscula) 		PF08240
(ADH_N)
PF13602
(ADH_zinc_N_2) 		4 ARG A 266
VAL A 269
VAL A 222
ILE A 225
 None
 1.00A 3remB-5dp2A:
undetectable		 3remB-5dp2A:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f5r HEAT SHOCK PROTEIN
75 KDA,
MITOCHONDRIAL

(Homo sapiens) 		PF13589
(HATPase_c_3) 		4 VAL A 211
ARG A 269
VAL A 270
ILE A 154
 None
 0.78A 3remB-5f5rA:
undetectable		 3remB-5f5rA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fg3 PROBABLE TRANSLATION
INITIATION FACTOR
IF-2

(Aeropyrum
pernix) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF11987
(IF-2)
PF14578
(GTP_EFTU_D4) 		4 VAL A 318
MET A 292
TYR A 313
ILE A 263
 None
 0.94A 3remB-5fg3A:
undetectable		 3remB-5fg3A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gj8 ACYL-COA
DEHYDROGENASE TYPE 2
DOMAIN PROTEIN

(Alicyclobacillus
acidocaldarius) 		PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
PF08028
(Acyl-CoA_dh_2) 		4 VAL A 234
VAL A 226
ILE A 229
GLN A 230
 None
 1.01A 3remB-5gj8A:
undetectable		 3remB-5gj8A:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5go2 PROTEIN AROA(G)

(Bacillus
subtilis) 		PF01817
(CM_2) 		5 ARG A  27
VAL A  31
ARG A  50
MET A  54
GLN A  86
 None
 0.86A 3remB-5go2A:
9.4		 3remB-5go2A:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hph HEAT SHOCK PROTEIN
75 KDA,
MITOCHONDRIAL

(Homo sapiens) 		PF00183
(HSP90)
PF13589
(HATPase_c_3) 		4 VAL A 211
ARG A 269
VAL A 270
ILE A 154
 None
 0.83A 3remB-5hphA:
undetectable		 3remB-5hphA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hsi PUTATIVE
DECARBOXYLASE

(Lactobacillus
brevis) 		PF00282
(Pyridoxal_deC) 		4 VAL A 488
VAL A 495
ILE A 609
GLN A 610
 None
 0.87A 3remB-5hsiA:
undetectable		 3remB-5hsiA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j6f 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE
SYNTHASE, CHORISMATE
MUTASE-ISOZYME 3

(Geobacillus sp.
GHH01) 		PF00793
(DAHP_synth_1)
PF01817
(CM_2) 		5 ARG A  27
VAL A  31
ARG A  50
MET A  54
GLN A  86
 PRE  A 404 (-3.4A)
PRE  A 404 ( 4.9A)
PRE  A 404 (-4.6A)
PRE  A 404 (-3.6A)
PRE  A 404 (-3.3A)
 0.69A 3remB-5j6fA:
10.5		 3remB-5j6fA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l9w ACETOPHENONE
CARBOXYLASE GAMMA
SUBUNIT

(Aromatoleum
aromaticum) 		PF01968
(Hydantoinase_A)
PF05378
(Hydant_A_N) 		4 ARG B 441
VAL B 695
TYR B 399
ILE B 400
 None
 1.00A 3remB-5l9wB:
undetectable		 3remB-5l9wB:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lsm FMN-DEPENDENT
NITRONATE
MONOOXYGENASE

(Shewanella
oneidensis) 		PF03060
(NMO) 		4 VAL A  32
VAL A 128
ILE A  16
GLN A  17
 None
 0.96A 3remB-5lsmA:
undetectable		 3remB-5lsmA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n4g HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 ARG H  98
VAL H   2
TYR H  27
GLN H   1
 EDO  H 302 (-3.5A)
None
None
None
 0.96A 3remB-5n4gH:
undetectable		 3remB-5n4gH:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB

(Escherichia
coli) 		PF00005
(ABC_tran)
PF02687
(FtsX)
PF12704
(MacB_PCD) 		4 VAL J 345
VAL J 314
ILE J 339
GLN J 340
 None
 0.93A 3remB-5nilJ:
5.1		 3remB-5nilJ:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tpx HISTONE
ACETYLTRANSFERASE
GCN5

(Plasmodium
falciparum) 		PF00439
(Bromodomain) 		4 MET A1406
TYR A1457
ILE A1453
GLN A1450
 None
 0.99A 3remB-5tpxA:
undetectable		 3remB-5tpxA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE

(Trichomonas
vaginalis) 		PF00177
(Ribosomal_S7) 		4 VAL F  53
VAL F 105
TYR F  27
ILE F  28
 None
 1.05A 3remB-5xyiF:
undetectable		 3remB-5xyiF:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yep TOXIN-ANTITOXIN
SYSTEM ANTIDOTE MNT
FAMILY

(Shewanella
oneidensis) 		no annotation 4 VAL A  86
TYR A  29
ILE A  42
GLN A  31
 None
 0.95A 3remB-5yepA:
undetectable		 3remB-5yepA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yt0 PROBABLE TRANSLATION
INITIATION FACTOR
IF-2

(Aeropyrum
pernix) 		no annotation 4 VAL A 318
MET A 292
TYR A 313
ILE A 263
 None
 0.99A 3remB-5yt0A:
undetectable		 3remB-5yt0A:
25.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bwc POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
CAPD

(Bacillus
thuringiensis) 		no annotation 4 VAL A 165
VAL A 170
MET A 203
ILE A  17
 None
NAP  A 401 (-4.0A)
None
NAP  A 401 (-3.8A)
 0.99A 3remB-6bwcA:
undetectable		 3remB-6bwcA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c4m YERSINOPINE
DEHYDROGENASE

(Yersinia pestis) 		no annotation 4 VAL C  71
ARG C 218
VAL C 215
ILE C  23
 None
 1.05A 3remB-6c4mC:
2.3		 3remB-6c4mC:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c66 CRISPR-ASSOCIATED
HELICASE, CAS3
FAMILY

(Thermobifida
fusca) 		no annotation 4 ARG G 622
VAL G 883
ILE G 914
GLN G 916
 None
 1.03A 3remB-6c66G:
undetectable		 3remB-6c66G:
28.04