SIMILAR PATTERNS OF AMINO ACIDS FOR 3R9V_B_DXCB323
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dbv | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Geobacillusstearothermophilus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | LEU O 333ILE O 144VAL O 321LEU O 324 | None | 0.60A | 3r9vA-1dbvO:0.03r9vB-1dbvO:0.0 | 3r9vA-1dbvO:22.693r9vB-1dbvO:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g8x | MYOSIN II HEAVYCHAIN FUSED TOALPHA-ACTININ 3 (Dictyosteliumdiscoideum) |
PF00063(Myosin_head)PF00435(Spectrin)PF02736(Myosin_N) | 4 | LEU A 592ILE A 347VAL A 608LEU A 611 | None | 0.70A | 3r9vA-1g8xA:0.03r9vB-1g8xA:0.0 | 3r9vA-1g8xA:15.673r9vB-1g8xA:15.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ii0 | ARSENICALPUMP-DRIVING ATPASE (Escherichiacoli) |
PF02374(ArsA_ATPase) | 4 | LEU A 4VAL A 285LEU A 288SER A 289 | None | 0.61A | 3r9vA-1ii0A:0.03r9vB-1ii0A:0.0 | 3r9vA-1ii0A:19.303r9vB-1ii0A:19.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1muu | GDP-MANNOSE6-DEHYDROGENASE (Pseudomonasaeruginosa) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 4 | ILE A 3ILE A 5LEU A 19SER A 20 | None | 0.69A | 3r9vA-1muuA:undetectable3r9vB-1muuA:undetectable | 3r9vA-1muuA:20.753r9vB-1muuA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pjm | IMPORTIN ALPHA-2SUBUNIT (Mus musculus) |
PF00514(Arm)PF16186(Arm_3) | 4 | ILE B 421VAL B 383LEU B 386SER B 387 | None | 0.65A | 3r9vA-1pjmB:0.93r9vB-1pjmB:undetectable | 3r9vA-1pjmB:19.103r9vB-1pjmB:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pjm | IMPORTIN ALPHA-2SUBUNIT (Mus musculus) |
PF00514(Arm)PF16186(Arm_3) | 4 | LEU B 343ILE B 320VAL B 295LEU B 298 | None | 0.66A | 3r9vA-1pjmB:0.93r9vB-1pjmB:undetectable | 3r9vA-1pjmB:19.103r9vB-1pjmB:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rrm | LACTALDEHYDEREDUCTASE (Escherichiacoli) |
PF00465(Fe-ADH) | 4 | ILE A 109ILE A 110VAL A 119LEU A 122 | None | 0.70A | 3r9vA-1rrmA:0.03r9vB-1rrmA:0.0 | 3r9vA-1rrmA:20.653r9vB-1rrmA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x1n | 4-ALPHA-GLUCANOTRANSFERASE (Solanumtuberosum) |
PF02446(Glyco_hydro_77) | 4 | LEU A 514ILE A 469LEU A 64SER A 63 | None | 0.69A | 3r9vA-1x1nA:undetectable3r9vB-1x1nA:undetectable | 3r9vA-1x1nA:20.683r9vB-1x1nA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ylf | RRF2 FAMILY PROTEIN (Bacillus cereus) |
PF02082(Rrf2) | 4 | ILE A 75VAL A 14LEU A 17SER A 18 | None | 0.68A | 3r9vA-1ylfA:0.03r9vB-1ylfA:0.0 | 3r9vA-1ylfA:23.223r9vB-1ylfA:23.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c1z | UDP-GLUCOSEFLAVONOID 3-OGLYCOSYLTRANSFERASE (Vitis vinifera) |
PF00201(UDPGT) | 4 | ILE A 276VAL A 289LEU A 292SER A 293 | None | 0.71A | 3r9vA-2c1zA:undetectable3r9vB-2c1zA:0.0 | 3r9vA-2c1zA:22.613r9vB-2c1zA:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d5l | DIPEPTIDYLAMINOPEPTIDASE IV,PUTATIVE (Porphyromonasgingivalis) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 4 | ILE A 442ILE A 444VAL A 55LEU A 57 | None | 0.67A | 3r9vA-2d5lA:undetectable3r9vB-2d5lA:undetectable | 3r9vA-2d5lA:17.973r9vB-2d5lA:17.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dbb | PUTATIVE HTH-TYPETRANSCRIPTIONALREGULATOR PH0061 (Pyrococcushorikoshii) |
PF13412(HTH_24) | 4 | ILE A 53VAL A 15LEU A 18SER A 19 | None | 0.69A | 3r9vA-2dbbA:undetectable3r9vB-2dbbA:undetectable | 3r9vA-2dbbA:21.723r9vB-2dbbA:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2et6 | (3R)-HYDROXYACYL-COADEHYDROGENASE (Candidatropicalis) |
PF00106(adh_short) | 4 | ILE A 191VAL A 221LEU A 224SER A 225 | None | 0.58A | 3r9vA-2et6A:undetectable3r9vB-2et6A:undetectable | 3r9vA-2et6A:18.453r9vB-2et6A:18.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h6e | D-ARABINOSE1-DEHYDROGENASE (Sulfolobussolfataricus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | ILE A 189VAL A 303LEU A 306SER A 307 | None | 0.67A | 3r9vA-2h6eA:undetectable3r9vB-2h6eA:undetectable | 3r9vA-2h6eA:21.143r9vB-2h6eA:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2him | L-ASPARAGINASE 1 (Escherichiacoli) |
PF00710(Asparaginase) | 4 | TRP A 68ILE A 71ILE A 75VAL A 112 | None | 0.59A | 3r9vA-2himA:undetectable3r9vB-2himA:undetectable | 3r9vA-2himA:22.313r9vB-2himA:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hun | 336AA LONGHYPOTHETICALDTDP-GLUCOSE4,6-DEHYDRATASE (Pyrococcushorikoshii) |
PF16363(GDP_Man_Dehyd) | 4 | ILE A 33ILE A 35VAL A 69LEU A 72 | None | 0.70A | 3r9vA-2hunA:undetectable3r9vB-2hunA:undetectable | 3r9vA-2hunA:22.323r9vB-2hunA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iuk | SEED LIPOXYGENASE (Glycine max) |
PF00305(Lipoxygenase)PF01477(PLAT) | 4 | ILE A 327ILE A 331VAL A 289LEU A 292 | None | 0.66A | 3r9vA-2iukA:undetectable3r9vB-2iukA:2.6 | 3r9vA-2iukA:16.593r9vB-2iukA:16.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2koj | PARTITIONINGDEFECTIVE 3 HOMOLOG (Mus musculus) |
PF00595(PDZ) | 4 | LEU A 494ILE A 488VAL A 528LEU A 531 | None | 0.71A | 3r9vA-2kojA:undetectable3r9vB-2kojA:undetectable | 3r9vA-2kojA:19.263r9vB-2kojA:19.26 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2p7n | PATHOGENICITY ISLAND1 EFFECTOR PROTEIN (Chromobacteriumviolaceum) |
PF06511(IpaD) | 4 | ILE A 185ILE A 189VAL A 379LEU A 382 | None | 0.65A | 3r9vA-2p7nA:12.23r9vB-2p7nA:13.3 | 3r9vA-2p7nA:34.773r9vB-2p7nA:34.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ph7 | UNCHARACTERIZEDPROTEIN AF_2093 (Archaeoglobusfulgidus) |
no annotation | 4 | ILE A 24VAL A 6LEU A 9SER A 10 | None | 0.52A | 3r9vA-2ph7A:undetectable3r9vB-2ph7A:undetectable | 3r9vA-2ph7A:22.803r9vB-2ph7A:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q50 | GLYOXYLATEREDUCTASE/HYDROXYPYRUVATE REDUCTASE (Homo sapiens) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 4 | LEU A 151ILE A 241ILE A 243LEU A 118 | None | 0.67A | 3r9vA-2q50A:undetectable3r9vB-2q50A:undetectable | 3r9vA-2q50A:22.023r9vB-2q50A:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rmz | INTEGRIN BETA-3 (Homo sapiens) |
no annotation | 4 | LEU A 706VAL A 695LEU A 698SER A 699 | None | 0.71A | 3r9vA-2rmzA:undetectable3r9vB-2rmzA:undetectable | 3r9vA-2rmzA:11.073r9vB-2rmzA:11.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rsv | SERINE/THREONINE-PROTEIN KINASE VRK1 (Homo sapiens) |
PF00069(Pkinase) | 4 | LEU A 165VAL A 154LEU A 157SER A 158 | None | 0.70A | 3r9vA-2rsvA:2.73r9vB-2rsvA:2.0 | 3r9vA-2rsvA:19.953r9vB-2rsvA:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w9z | G1/S-SPECIFICCYCLIN-D1 (Homo sapiens) |
PF00134(Cyclin_N)PF02984(Cyclin_C) | 4 | ILE A 177ILE A 178VAL A 212LEU A 215 | None | 0.62A | 3r9vA-2w9zA:undetectable3r9vB-2w9zA:undetectable | 3r9vA-2w9zA:19.533r9vB-2w9zA:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xua | 3-OXOADIPATEENOL-LACTONASE (Paraburkholderiaxenovorans) |
PF12146(Hydrolase_4) | 4 | ILE A 29VAL A 46LEU A 49SER A 50 | None | 0.57A | 3r9vA-2xuaA:undetectable3r9vB-2xuaA:undetectable | 3r9vA-2xuaA:22.153r9vB-2xuaA:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zbk | TYPE II DNATOPOISOMERASE VISUBUNIT A (Sulfolobusshibatae) |
PF04406(TP6A_N) | 4 | ILE A 229ILE A 231VAL A 245LEU A 248 | None | 0.50A | 3r9vA-2zbkA:undetectable3r9vB-2zbkA:undetectable | 3r9vA-2zbkA:20.963r9vB-2zbkA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3apm | PROTEIN-ARGININEDEIMINASE TYPE-4 (Homo sapiens) |
PF03068(PAD)PF08526(PAD_N)PF08527(PAD_M) | 4 | ILE A 565ILE A 567VAL A 616LEU A 619 | None | 0.49A | 3r9vA-3apmA:undetectable3r9vB-3apmA:undetectable | 3r9vA-3apmA:17.223r9vB-3apmA:17.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b5e | MLL8374 PROTEIN (Mesorhizobiumjaponicum) |
no annotation | 4 | ILE A 162VAL A 179LEU A 182SER A 183 | None | 0.67A | 3r9vA-3b5eA:undetectable3r9vB-3b5eA:undetectable | 3r9vA-3b5eA:21.413r9vB-3b5eA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ble | CITRAMALATE SYNTHASEFROM LEPTOSPIRAINTERROGANS (Leptospirainterrogans) |
PF00682(HMGL-like) | 4 | ILE A 171ILE A 174VAL A 163LEU A 166 | None | 0.68A | 3r9vA-3bleA:undetectable3r9vB-3bleA:undetectable | 3r9vA-3bleA:24.453r9vB-3bleA:24.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3blz | NTF2-LIKE PROTEIN OFUNKNOWN FUNCTION (Shewanellabaltica) |
PF12893(Lumazine_bd_2) | 4 | ILE A 91VAL A 14LEU A 17SER A 18 | None | 0.56A | 3r9vA-3blzA:undetectable3r9vB-3blzA:undetectable | 3r9vA-3blzA:18.533r9vB-3blzA:18.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ctt | MALTASE-GLUCOAMYLASE (Homo sapiens) |
PF00088(Trefoil)PF01055(Glyco_hydro_31)PF16863(NtCtMGAM_N) | 4 | ILE A 816ILE A 756VAL A 791LEU A 796 | None | 0.68A | 3r9vA-3cttA:undetectable3r9vB-3cttA:undetectable | 3r9vA-3cttA:16.093r9vB-3cttA:16.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3djl | PROTEIN AIDB (Escherichiacoli) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M) | 4 | ILE A 318ILE A 332LEU A 341SER A 342 | None | 0.66A | 3r9vA-3djlA:1.73r9vB-3djlA:1.1 | 3r9vA-3djlA:18.623r9vB-3djlA:18.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f8t | PREDICTED ATPASEINVOLVED INREPLICATION CONTROL,CDC46/MCM FAMILY (Methanopyruskandleri) |
PF00493(MCM) | 4 | ILE A 121ILE A 119VAL A 167LEU A 172 | None | 0.70A | 3r9vA-3f8tA:undetectable3r9vB-3f8tA:undetectable | 3r9vA-3f8tA:20.043r9vB-3f8tA:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3geu | INTERCELLULARADHESION PROTEIN R (Staphylococcusaureus) |
PF00440(TetR_N) | 4 | ILE A 110ILE A 114LEU A 99SER A 100 | None | 0.57A | 3r9vA-3geuA:undetectable3r9vB-3geuA:undetectable | 3r9vA-3geuA:23.663r9vB-3geuA:23.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gq2 | GENERAL VESICULARTRANSPORT FACTORP115 (Bos taurus) |
PF04869(Uso1_p115_head) | 4 | LEU A 146ILE A 200ILE A 203LEU A 162 | None | 0.72A | 3r9vA-3gq2A:undetectable3r9vB-3gq2A:undetectable | 3r9vA-3gq2A:19.453r9vB-3gq2A:19.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ho6 | TOXIN A (Clostridioidesdifficile) |
PF11713(Peptidase_C80) | 4 | LEU A 19ILE A 41ILE A 111LEU A 57 | None | 0.67A | 3r9vA-3ho6A:undetectable3r9vB-3ho6A:undetectable | 3r9vA-3ho6A:23.573r9vB-3ho6A:23.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3il3 | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 3 (Haemophilusinfluenzae) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 4 | ILE A 249VAL A 216LEU A 219SER A 220 | None | 0.70A | 3r9vA-3il3A:undetectable3r9vB-3il3A:undetectable | 3r9vA-3il3A:22.513r9vB-3il3A:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jd5 | 28S RIBOSOMALPROTEIN S18C,MITOCHONDRIAL (Bos taurus) |
PF01084(Ribosomal_S18) | 4 | ILE R 112VAL R 78LEU R 81SER R 82 | None | 0.68A | 3r9vA-3jd5R:undetectable3r9vB-3jd5R:undetectable | 3r9vA-3jd5R:17.453r9vB-3jd5R:17.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l3f | PROTEIN DOA1 (Saccharomycescerevisiae) |
PF08324(PUL)PF09070(PFU) | 4 | ILE X 599ILE X 603VAL X 622LEU X 625 | None | 0.68A | 3r9vA-3l3fX:undetectable3r9vB-3l3fX:undetectable | 3r9vA-3l3fX:22.313r9vB-3l3fX:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lkw | FUSION PROTEIN OFNONSTRUCTURALPROTEIN 2B ANDNONSTRUCTURALPROTEIN 3 (Dengue virus) |
PF00949(Peptidase_S7)PF01002(Flavi_NS2B) | 4 | LEU A 126ILE A 215ILE A 176VAL A 147 | None | 0.70A | 3r9vA-3lkwA:undetectable3r9vB-3lkwA:undetectable | 3r9vA-3lkwA:21.923r9vB-3lkwA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ntx | CYTOPLASMICL-ASPARAGINASE I (Yersinia pestis) |
PF00710(Asparaginase) | 4 | TRP A 68ILE A 71ILE A 75VAL A 112 | None | 0.61A | 3r9vA-3ntxA:undetectable3r9vB-3ntxA:undetectable | 3r9vA-3ntxA:23.763r9vB-3ntxA:23.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nzp | ARGININEDECARBOXYLASE (Campylobacterjejuni) |
PF02784(Orn_Arg_deC_N) | 4 | ILE A 34ILE A 31VAL A 331LEU A 49 | None | 0.67A | 3r9vA-3nzpA:undetectable3r9vB-3nzpA:2.7 | 3r9vA-3nzpA:18.773r9vB-3nzpA:18.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o3p | MANNOSYL-3-PHOSPHOGLYCERATE SYNTHASE (Rubrobacterxylanophilus) |
PF00535(Glycos_transf_2) | 5 | ILE A 60ILE A 61VAL A 79LEU A 48SER A 50 | None | 0.95A | 3r9vA-3o3pA:undetectable3r9vB-3o3pA:undetectable | 3r9vA-3o3pA:20.203r9vB-3o3pA:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p8c | WISKOTT-ALDRICHSYNDROME PROTEINFAMILY MEMBER 1PROBABLE PROTEINBRICK1 (Homo sapiens;Homo sapiens) |
PF02205(WH2)no annotation | 5 | ILE E 64ILE E 61VAL D 73LEU D 76SER D 77 | None | 1.33A | 3r9vA-3p8cE:undetectable3r9vB-3p8cE:undetectable | 3r9vA-3p8cE:15.023r9vB-3p8cE:15.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r0h | INACTIVATION-NO-AFTER-POTENTIAL DPROTEIN (Drosophilamelanogaster) |
PF00595(PDZ) | 4 | ILE A 541ILE A 546VAL A 556LEU A 559 | None | 0.61A | 3r9vA-3r0hA:undetectable3r9vB-3r0hA:undetectable | 3r9vA-3r0hA:23.163r9vB-3r0hA:23.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sg1 | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE 1 (Bacillusanthracis) |
PF00275(EPSP_synthase) | 4 | ILE A 28ILE A 29VAL A 72LEU A 42 | None | 0.61A | 3r9vA-3sg1A:undetectable3r9vB-3sg1A:undetectable | 3r9vA-3sg1A:20.923r9vB-3sg1A:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tmc | UNCHARACTERIZEDPROTEIN (Bdellovibriobacteriovorus) |
PF13487(HD_5) | 4 | LEU A 165VAL A 154LEU A 157SER A 158 | None | 0.70A | 3r9vA-3tmcA:undetectable3r9vB-3tmcA:undetectable | 3r9vA-3tmcA:22.293r9vB-3tmcA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3to3 | PETROBACTINBIOSYNTHESIS PROTEINASBB (Bacillusanthracis) |
PF04183(IucA_IucC)PF06276(FhuF) | 4 | ILE A 419ILE A 423VAL A 505LEU A 509 | None | 0.63A | 3r9vA-3to3A:undetectable3r9vB-3to3A:undetectable | 3r9vA-3to3A:19.153r9vB-3to3A:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3unv | ADMH (Pantoeaagglomerans) |
PF00221(Lyase_aromatic) | 4 | LEU A 408VAL A 246LEU A 249SER A 250 | None | 0.70A | 3r9vA-3unvA:1.43r9vB-3unvA:2.0 | 3r9vA-3unvA:21.783r9vB-3unvA:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wh3 | C-TYPE LECTIN DOMAINFAMILY 4 MEMBER E (Homo sapiens) |
PF00059(Lectin_C) | 4 | ILE A 204ILE A 139LEU A 127SER A 128 | None | 0.68A | 3r9vA-3wh3A:undetectable3r9vB-3wh3A:undetectable | 3r9vA-3wh3A:19.003r9vB-3wh3A:19.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zc4 | SSO1398 (Sulfolobussolfataricus) |
no annotation | 5 | ILE A 19ILE A 11VAL A 153LEU A 157SER A 156 | None | 1.35A | 3r9vA-3zc4A:undetectable3r9vB-3zc4A:undetectable | 3r9vA-3zc4A:21.623r9vB-3zc4A:21.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3zqb | PROTEIN PRGI, CELLINVASION PROTEINSIPD (Salmonellaenterica) |
PF06511(IpaD)PF09392(T3SS_needle_F) | 4 | ILE A 142VAL A 323LEU A 326SER A 327 | None | 0.41A | 3r9vA-3zqbA:19.63r9vB-3zqbA:15.6 | 3r9vA-3zqbA:39.603r9vB-3zqbA:39.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a8j | ELONGATOR COMPLEXPROTEIN 4 (Saccharomycescerevisiae) |
PF05625(PAXNEB) | 4 | ILE A 276ILE A 272VAL A 314LEU A 317 | None | 0.68A | 3r9vA-4a8jA:undetectable3r9vB-4a8jA:undetectable | 3r9vA-4a8jA:22.863r9vB-4a8jA:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b4s | BCL-2-LIKE PROTEIN10 (Homo sapiens) |
PF00452(Bcl-2) | 4 | LEU A 146VAL A 131LEU A 134SER A 135 | None | 0.53A | 3r9vA-4b4sA:undetectable3r9vB-4b4sA:undetectable | 3r9vA-4b4sA:21.433r9vB-4b4sA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bv6 | APOPTOSIS-INDUCINGFACTOR 1,MITOCHONDRIAL (Homo sapiens) |
PF07992(Pyr_redox_2)PF14721(AIF_C) | 4 | ILE A 587ILE A 591VAL A 604LEU A 607 | None | 0.66A | 3r9vA-4bv6A:undetectable3r9vB-4bv6A:undetectable | 3r9vA-4bv6A:19.883r9vB-4bv6A:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c8q | DNA TOPOISOMERASE2-ASSOCIATED PROTEINPAT1 (Saccharomycescerevisiae) |
PF09770(PAT1) | 4 | ILE H 636VAL H 596LEU H 599SER H 600 | None | 0.70A | 3r9vA-4c8qH:undetectable3r9vB-4c8qH:undetectable | 3r9vA-4c8qH:23.233r9vB-4c8qH:23.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4czw | PAB-DEPENDENTPOLY(A)-SPECIFICRIBONUCLEASE SUBUNITPAN2 (Neurosporacrassa) |
PF00929(RNase_T)PF13423(UCH_1) | 4 | LEU A1089ILE A1052LEU A1040SER A1039 | None | 0.67A | 3r9vA-4czwA:undetectable3r9vB-4czwA:undetectable | 3r9vA-4czwA:19.503r9vB-4czwA:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ejr | MAJOR CAPSID PROTEINVP60 (Rabbithemorrhagicdisease virus) |
PF00915(Calici_coat) | 4 | LEU A 173ILE A 142ILE A 144VAL A 150 | None | 0.51A | 3r9vA-4ejrA:undetectable3r9vB-4ejrA:undetectable | 3r9vA-4ejrA:21.543r9vB-4ejrA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4es9 | EPF (Streptococcuspyogenes) |
no annotation | 5 | LEU A 145ILE A 153VAL A 226LEU A 225SER A 224 | None | 1.01A | 3r9vA-4es9A:undetectable3r9vB-4es9A:undetectable | 3r9vA-4es9A:23.013r9vB-4es9A:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ha6 | PYRIDOXINE 4-OXIDASE (Mesorhizobiumloti) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 4 | ILE A 20ILE A 22LEU A 36SER A 37 | None | 0.67A | 3r9vA-4ha6A:undetectable3r9vB-4ha6A:undetectable | 3r9vA-4ha6A:17.723r9vB-4ha6A:17.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hxt | DE NOVO PROTEINOR329 (syntheticconstruct) |
PF00514(Arm) | 4 | LEU A 220ILE A 197VAL A 172LEU A 175 | None | 0.66A | 3r9vA-4hxtA:undetectable3r9vB-4hxtA:undetectable | 3r9vA-4hxtA:23.383r9vB-4hxtA:23.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iik | ADENOSINEMONOPHOSPHATE-PROTEIN HYDROLASE SIDD (Legionellapneumophila) |
no annotation | 4 | LEU A 139ILE A 156VAL A 128LEU A 131 | None | 0.70A | 3r9vA-4iikA:undetectable3r9vB-4iikA:undetectable | 3r9vA-4iikA:20.823r9vB-4iikA:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4irf | MALARIAL CLPB2ATPASE/HSP101PROTEIN (Plasmodiumfalciparum) |
PF02861(Clp_N) | 4 | ILE A 40ILE A 19VAL A 114LEU A 117 | None | 0.65A | 3r9vA-4irfA:undetectable3r9vB-4irfA:undetectable | 3r9vA-4irfA:23.793r9vB-4irfA:23.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jcl | CYCLOMALTODEXTRINGLUCANOTRANSFERASE (Paenibacillusmacerans) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG) | 4 | TRP A 54ILE A 57ILE A 61LEU A 74 | None | 0.55A | 3r9vA-4jclA:undetectable3r9vB-4jclA:undetectable | 3r9vA-4jclA:18.563r9vB-4jclA:18.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jcm | CYCLODEXTRINGLUCANOTRANSFERASE ([Bacillus]clarkii) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG) | 4 | TRP A 54ILE A 57ILE A 61LEU A 74 | None | 0.53A | 3r9vA-4jcmA:undetectable3r9vB-4jcmA:undetectable | 3r9vA-4jcmA:17.693r9vB-4jcmA:17.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jof | GOLGI-ASSOCIATED PDZAND COILED-COILMOTIF-CONTAININGPROTEIN (Homo sapiens) |
PF00595(PDZ) | 4 | ILE A 303VAL A 353LEU A 356SER A 357 | None | 0.56A | 3r9vA-4jofA:undetectable3r9vB-4jofA:undetectable | 3r9vA-4jofA:16.913r9vB-4jofA:16.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kdx | GLUTATHIONES-TRANSFERASE DOMAIN (Paraburkholderiagraminis) |
PF00043(GST_C)PF13417(GST_N_3) | 4 | LEU A 192ILE A 97LEU A 160SER A 159 | None | 0.72A | 3r9vA-4kdxA:2.13r9vB-4kdxA:undetectable | 3r9vA-4kdxA:22.223r9vB-4kdxA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lik | DNA PRIMASE SMALLSUBUNIT (Homo sapiens) |
PF01896(DNA_primase_S) | 4 | ILE A 142VAL A 186LEU A 189SER A 190 | None | 0.40A | 3r9vA-4likA:undetectable3r9vB-4likA:undetectable | 3r9vA-4likA:22.583r9vB-4likA:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m5p | NADPH DEHYDROGENASE (Scheffersomycesstipitis) |
PF00724(Oxidored_FMN) | 4 | ILE A 280ILE A 283VAL A 267LEU A 270 | None | 0.68A | 3r9vA-4m5pA:undetectable3r9vB-4m5pA:undetectable | 3r9vA-4m5pA:22.753r9vB-4m5pA:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rv1 | ENGINEERED PROTEINOR497 (syntheticconstruct) |
PF00514(Arm) | 4 | LEU A 178ILE A 155VAL A 130LEU A 133 | None | 0.67A | 3r9vA-4rv1A:undetectable3r9vB-4rv1A:undetectable | 3r9vA-4rv1A:23.153r9vB-4rv1A:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rv1 | ENGINEERED PROTEINOR497 (syntheticconstruct) |
PF00514(Arm) | 4 | LEU A 220ILE A 197VAL A 172LEU A 175 | None | 0.69A | 3r9vA-4rv1A:undetectable3r9vB-4rv1A:undetectable | 3r9vA-4rv1A:23.153r9vB-4rv1A:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rv1 | ENGINEERED PROTEINOR497 (syntheticconstruct) |
PF00514(Arm) | 4 | LEU A 262ILE A 239VAL A 214LEU A 217 | None | 0.65A | 3r9vA-4rv1A:undetectable3r9vB-4rv1A:undetectable | 3r9vA-4rv1A:23.153r9vB-4rv1A:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rxx | UBIQUITINCARBOXYL-TERMINALHYDROLASE 38 (Homo sapiens) |
no annotation | 4 | ILE A 103ILE A 107VAL A 85LEU A 88 | None | 0.64A | 3r9vA-4rxxA:undetectable3r9vB-4rxxA:undetectable | 3r9vA-4rxxA:19.303r9vB-4rxxA:19.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tr1 | GLUTAREDOXIN 3 (Alkaliphilusoremlandii) |
PF00462(Glutaredoxin) | 5 | ILE A 4ILE A 6VAL A 19LEU A 22SER A 23 | None | 0.89A | 3r9vA-4tr1A:undetectable3r9vB-4tr1A:undetectable | 3r9vA-4tr1A:15.443r9vB-4tr1A:15.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u0t | ADC-7 BETA-LACTAMASE (Acinetobacterbaumannii) |
PF00144(Beta-lactamase) | 5 | LEU A 232ILE A 331ILE A 357VAL A 353LEU A 354 | None | 1.32A | 3r9vA-4u0tA:undetectable3r9vB-4u0tA:undetectable | 3r9vA-4u0tA:21.783r9vB-4u0tA:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u5a | SPOROZOITE MICRONEMEPROTEIN ESSENTIALFOR CELL TRAVERSAL (Plasmodiumberghei) |
no annotation | 4 | ILE A 79VAL A 91LEU A 94SER A 95 | None | 0.53A | 3r9vA-4u5aA:undetectable3r9vB-4u5aA:3.2 | 3r9vA-4u5aA:23.213r9vB-4u5aA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uu5 | MAGUK P55 SUBFAMILYMEMBER 5 (Homo sapiens) |
PF00595(PDZ) | 4 | ILE A 307ILE A 309VAL A 317LEU A 320 | None | 0.62A | 3r9vA-4uu5A:undetectable3r9vB-4uu5A:undetectable | 3r9vA-4uu5A:13.843r9vB-4uu5A:13.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ybg | PROTEIN MAELSTROM (Drosophilamelanogaster) |
PF13017(Maelstrom) | 4 | ILE A 239VAL A 194LEU A 197SER A 198 | None | 0.71A | 3r9vA-4ybgA:undetectable3r9vB-4ybgA:undetectable | 3r9vA-4ybgA:21.573r9vB-4ybgA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aga | DNA POLYMERASE THETA (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C) | 4 | ILE A 493ILE A 495VAL A 326LEU A 329 | None | 0.69A | 3r9vA-5agaA:undetectable3r9vB-5agaA:undetectable | 3r9vA-5agaA:15.733r9vB-5agaA:15.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c6u | AMINOTRANSFERASE (Mycobacteriumtuberculosis) |
PF12897(Aminotran_MocR) | 4 | ILE A 391ILE A 393VAL A 407LEU A 410 | None | 0.70A | 3r9vA-5c6uA:undetectable3r9vB-5c6uA:undetectable | 3r9vA-5c6uA:22.273r9vB-5c6uA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 4 | ILE A 233VAL A 215LEU A 218SER A 219 | None | 0.55A | 3r9vA-5dqfA:undetectable3r9vB-5dqfA:undetectable | 3r9vA-5dqfA:18.733r9vB-5dqfA:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fq6 | PUTATIVE LIPOPROTEIN (Bacteroidesthetaiotaomicron) |
PF12771(SusD-like_2) | 4 | ILE A 270VAL A 255LEU A 258SER A 259 | None | 0.60A | 3r9vA-5fq6A:undetectable3r9vB-5fq6A:undetectable | 3r9vA-5fq6A:20.753r9vB-5fq6A:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jkq | PFVFT1 (Plasmodiumfalciparum) |
no annotation | 4 | ILE A 127ILE A 128VAL A 42LEU A 45 | None | 0.70A | 3r9vA-5jkqA:undetectable3r9vB-5jkqA:undetectable | 3r9vA-5jkqA:23.353r9vB-5jkqA:23.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5liq | NICKING ENDONUCLEASEN.BSPD6I (Bacillus sp.(in: Bacteria)) |
PF09491(RE_AlwI) | 5 | ILE A 268ILE A 271VAL A 139LEU A 142SER A 143 | None | 0.81A | 3r9vA-5liqA:undetectable3r9vB-5liqA:2.1 | 3r9vA-5liqA:20.673r9vB-5liqA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mc9 | LAMININ SUBUNITALPHA-1 (Mus musculus) |
PF00054(Laminin_G_1)PF06009(Laminin_II) | 4 | LEU A2292ILE A2212VAL A2177LEU A2163 | None | 0.69A | 3r9vA-5mc9A:undetectable3r9vB-5mc9A:undetectable | 3r9vA-5mc9A:18.793r9vB-5mc9A:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oqj | TRANSCRIPTIONINITIATION FACTORIIE SUBUNIT ALPHA (Saccharomycescerevisiae) |
no annotation | 4 | ILE W 98ILE W 95VAL W 9LEU W 12 | None | 0.66A | 3r9vA-5oqjW:undetectable3r9vB-5oqjW:3.0 | 3r9vA-5oqjW:undetectable3r9vB-5oqjW:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oqm | TRANSCRIPTION FACTORTFIIE SUBUNIT (Saccharomycescerevisiae) |
no annotation | 4 | ILE W 98ILE W 95VAL W 9LEU W 12 | None | 0.69A | 3r9vA-5oqmW:undetectable3r9vB-5oqmW:2.3 | 3r9vA-5oqmW:undetectable3r9vB-5oqmW:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 4 | ILE A 233VAL A 215LEU A 218SER A 219 | None | 0.52A | 3r9vA-5oriA:undetectable3r9vB-5oriA:2.1 | 3r9vA-5oriA:19.043r9vB-5oriA:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tj6 | HIGH CONDUCTANCECALCIUM-ACTIVATEDPOTASSIUM CHANNEL (Aplysiacalifornica) |
PF00520(Ion_trans)PF03493(BK_channel_a) | 4 | LEU A 798ILE A 754VAL A 825LEU A 745 | None | 0.70A | 3r9vA-5tj6A:3.43r9vB-5tj6A:2.8 | 3r9vA-5tj6A:14.733r9vB-5tj6A:14.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u09 | CANNABINOID RECEPTOR1,GLGA GLYCOGENSYNTHASE (Homo sapiens;Pyrococcusabyssi) |
PF00001(7tm_1)PF00534(Glycos_transf_1) | 4 | ILE A1070ILE A1072VAL A1105LEU A1108 | None | 0.69A | 3r9vA-5u09A:1.03r9vB-5u09A:3.2 | 3r9vA-5u09A:21.763r9vB-5u09A:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u6s | UDP-GLYCOSYLTRANSFERASE 74F2 (Arabidopsisthaliana) |
PF00201(UDPGT) | 4 | ILE A 156VAL A 141LEU A 144SER A 145 | None | 0.57A | 3r9vA-5u6sA:undetectable3r9vB-5u6sA:undetectable | 3r9vA-5u6sA:21.013r9vB-5u6sA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ufl | PROTEIN CIP2A (Homo sapiens) |
no annotation | 5 | ILE A 238ILE A 241VAL A 206LEU A 209SER A 210 | None | 1.09A | 3r9vA-5uflA:undetectable3r9vB-5uflA:undetectable | 3r9vA-5uflA:19.963r9vB-5uflA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ul4 | OXSB PROTEIN (Bacillusmegaterium) |
PF02310(B12-binding) | 4 | LEU A 292ILE A 358ILE A 392LEU A 342 | None | 0.64A | 3r9vA-5ul4A:2.83r9vB-5ul4A:undetectable | 3r9vA-5ul4A:18.013r9vB-5ul4A:18.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vjc | PROTEIN MINISPINDLES (Drosophilamelanogaster) |
no annotation | 4 | ILE A1339VAL A1377LEU A1380SER A1381 | None | 0.70A | 3r9vA-5vjcA:undetectable3r9vB-5vjcA:undetectable | 3r9vA-5vjcA:23.773r9vB-5vjcA:23.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vm9 | PROTEIN ARGONAUTE-3 (Homo sapiens) |
no annotation | 4 | TRP A 452ILE A 520ILE A 522VAL A 553 | None | 0.66A | 3r9vA-5vm9A:undetectable3r9vB-5vm9A:undetectable | 3r9vA-5vm9A:15.343r9vB-5vm9A:15.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vyl | INNER TEGUMENTPROTEIN (Humanalphaherpesvirus1) |
PF03970(Herpes_UL37_1) | 4 | ILE A 136ILE A 140VAL A 115LEU A 118 | None | 0.71A | 3r9vA-5vylA:2.63r9vB-5vylA:2.5 | 3r9vA-5vylA:18.733r9vB-5vylA:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wln | TYPE II SECRETIONSYSTEM PROTEIN D (Pseudomonasaeruginosa) |
no annotation | 4 | LEU G 252ILE G 292VAL G 310LEU G 313 | None | 0.59A | 3r9vA-5wlnG:undetectable3r9vB-5wlnG:undetectable | 3r9vA-5wlnG:18.863r9vB-5wlnG:18.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x55 | PROBABLE URACIL-DNAGLYCOSYLASE (Acanthamoebapolyphagamimivirus) |
PF03167(UDG) | 4 | LEU A 279ILE A 247VAL A 177LEU A 178 | None | 0.70A | 3r9vA-5x55A:undetectable3r9vB-5x55A:undetectable | 3r9vA-5x55A:22.193r9vB-5x55A:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zgb | PSAK (Cyanidioschyzonmerolae) |
no annotation | 4 | ILE K 12VAL K 51LEU K 54SER K 55 | None | 0.67A | 3r9vA-5zgbK:undetectable3r9vB-5zgbK:undetectable | 3r9vA-5zgbK:undetectable3r9vB-5zgbK:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eux | POLYMERASE BASICPROTEIN 2 (Influenza Bvirus) |
no annotation | 4 | ILE A 269ILE A 273LEU A 503SER A 504 | None | 0.62A | 3r9vA-6euxA:undetectable3r9vB-6euxA:undetectable | 3r9vA-6euxA:undetectable3r9vB-6euxA:undetectable |