SIMILAR PATTERNS OF AMINO ACIDS FOR 3R9T_C_BEZC264_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aoc | COAGULOGEN (Tachypleustridentatus) |
PF02035(Coagulin) | 4 | ALA A 33GLU A 31GLU A 35ALA A 113 | None | 1.05A | 3r9tC-1aocA:undetectable | 3r9tC-1aocA:21.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1dub | 2-ENOYL-COAHYDRATASE (Rattusnorvegicus) |
PF00378(ECH_1) | 4 | ALA A 98GLU A 144GLU A 164ALA A 173 | CAA A 300 (-3.6A)CAA A 300 ( 3.0A)CAA A 300 ( 3.5A)CAA A 300 ( 4.7A) | 0.38A | 3r9tC-1dubA:26.6 | 3r9tC-1dubA:36.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1efp | PROTEIN (ELECTRONTRANSFERFLAVOPROTEIN) (Paracoccusdenitrificans) |
PF00766(ETF_alpha)PF01012(ETF) | 4 | ALA A 22GLU A 8ALA A 91MET A 99 | None | 1.43A | 3r9tC-1efpA:undetectable | 3r9tC-1efpA:26.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jgc | BACTERIOFERRITIN (Rhodobactercapsulatus) |
PF00210(Ferritin) | 4 | ALA A 21GLU A 127GLU A 94ALA A 97 | None | 1.49A | 3r9tC-1jgcA:undetectable | 3r9tC-1jgcA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jgc | BACTERIOFERRITIN (Rhodobactercapsulatus) |
PF00210(Ferritin) | 4 | ALA A 97GLU A 51GLU A 18ALA A 21 | None | 1.42A | 3r9tC-1jgcA:undetectable | 3r9tC-1jgcA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1keh | PRECURSOR OFCEPHALOSPORINACYLASE (Brevundimonasdiminuta) |
PF01804(Penicil_amidase) | 4 | ALA A 665GLU A 624ALA A 596MET A 585 | None | 1.45A | 3r9tC-1kehA:undetectable | 3r9tC-1kehA:19.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mro | METHYL-COENZYME MREDUCTASE (Methanothermobactermarburgensis) |
PF02249(MCR_alpha)PF02745(MCR_alpha_N) | 4 | ALA A 114GLU A 259ALA A 254MET A 235 | None | 1.18A | 3r9tC-1mroA:undetectable | 3r9tC-1mroA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nfg | D-HYDANTOINASE (Ralstoniapickettii) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 4 | ALA A 187GLU A 217ALA A 218MET A 158 | None | 1.43A | 3r9tC-1nfgA:undetectable | 3r9tC-1nfgA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sef | CONSERVEDHYPOTHETICAL PROTEIN (Enterococcusfaecalis) |
PF05899(Cupin_3)PF07883(Cupin_2) | 4 | ALA A 240GLU A 163GLU A 199ALA A 196 | None | 1.08A | 3r9tC-1sefA:undetectable | 3r9tC-1sefA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tuu | ACETATE KINASE (Methanosarcinathermophila) |
PF00871(Acetate_kinase) | 4 | ALA A 301GLU A 299GLU A 303ALA A 291 | None | 1.32A | 3r9tC-1tuuA:undetectable | 3r9tC-1tuuA:25.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wuf | HYPOTHETICAL PROTEINLIN2664 (Listeriainnocua) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ALA A1265GLU A1059GLU A1098ALA A1100 | None | 1.44A | 3r9tC-1wufA:undetectable | 3r9tC-1wufA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yuz | NIGERYTHRIN (Desulfovibriovulgaris) |
PF02915(Rubrerythrin) | 4 | ALA A 148GLU A 73GLU A 115ALA A 72 | NoneFE2 A 302 ( 2.4A)FE2 A 302 (-1.9A)None | 1.28A | 3r9tC-1yuzA:undetectable | 3r9tC-1yuzA:24.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zsw | GLYOXALASE FAMILYPROTEIN (Bacillus cereus) |
PF00903(Glyoxalase) | 4 | ALA A 309GLU A 64ALA A 17MET A 35 | None | 1.39A | 3r9tC-1zswA:undetectable | 3r9tC-1zswA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ej0 | BRANCHED-CHAIN AMINOACIDAMINOTRANSFERASE (Thermusthermophilus) |
PF01063(Aminotran_4) | 4 | ALA A 139GLU A 197GLU A 181ALA A 258 | None | 1.33A | 3r9tC-2ej0A:undetectable | 3r9tC-2ej0A:23.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f9y | ACETYL-COACARBOXYLASE,CARBOXYLTRANSFERASEALPHA CHAIN (Escherichiacoli) |
PF03255(ACCA) | 4 | ALA A 64GLU A 231ALA A 244MET A 251 | None | 1.45A | 3r9tC-2f9yA:10.8 | 3r9tC-2f9yA:23.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fbq | PROBABLETRANSCRIPTIONALREGULATOR (Pseudomonasaeruginosa) |
PF00440(TetR_N) | 4 | ALA A 148GLU A 87ALA A 204MET A 164 | None | 1.46A | 3r9tC-2fbqA:undetectable | 3r9tC-2fbqA:25.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fzf | HYPOTHETICAL PROTEIN (Pyrococcusfuriosus) |
PF02915(Rubrerythrin) | 4 | ALA A 35GLU A 147GLU A 117ALA A 120 | None | 1.32A | 3r9tC-2fzfA:undetectable | 3r9tC-2fzfA:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iag | PROSTACYCLINSYNTHASE (Homo sapiens) |
PF00067(p450) | 4 | ALA A 274GLU A 270GLU A 271ALA A 244 | None | 1.41A | 3r9tC-2iagA:undetectable | 3r9tC-2iagA:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nyz | HYPOTHETICAL PROTEINGAMMAHV.M3 (Muridgammaherpesvirus4) |
PF09213(M3) | 4 | ALA A 34GLU A 41ALA A 40MET A 155 | None | 1.35A | 3r9tC-2nyzA:undetectable | 3r9tC-2nyzA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p9b | POSSIBLE PROLIDASE (Bifidobacteriumlongum) |
PF01979(Amidohydro_1) | 4 | ALA A 190GLU A 186ALA A 178MET A 224 | None | 1.15A | 3r9tC-2p9bA:undetectable | 3r9tC-2p9bA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v9p | REPLICATION PROTEINE1 (Deltapapillomavirus4) |
PF00519(PPV_E1_C) | 4 | ALA A 355GLU A 328ALA A 332MET A 316 | None | 1.47A | 3r9tC-2v9pA:undetectable | 3r9tC-2v9pA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vzb | PUTATIVEBACTERIOFERRITIN-RELATED PROTEIN (Bacteroidesfragilis) |
PF00210(Ferritin) | 4 | ALA A 117GLU A 62GLU A 29ALA A 32 | FE A6205 ( 4.9A) FE A6205 ( 2.5A) FE A6204 (-1.9A)None | 1.40A | 3r9tC-2vzbA:undetectable | 3r9tC-2vzbA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x58 | PEROXISOMALBIFUNCTIONAL ENZYME (Rattusnorvegicus) |
PF00378(ECH_1)PF00725(3HCDH)PF02737(3HCDH_N) | 4 | ALA A 61GLU A 103GLU A 123ALA A 132 | GOL A 770 (-4.1A)GOL A 770 (-2.9A)GOL A 770 ( 3.5A)GOL A 770 (-3.8A) | 0.37A | 3r9tC-2x58A:20.0 | 3r9tC-2x58A:16.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xvn | ASPERGILLUSFUMIGATUS CHITINASEA1 (Aspergillusfumigatus) |
PF00704(Glyco_hydro_18) | 4 | ALA A 314GLU A 50GLU A 318ALA A 328 | None | 1.22A | 3r9tC-2xvnA:undetectable | 3r9tC-2xvnA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ayx | MEMBRANE-BOUNDHYDROGENASE SMALLSUBUNIT (Hydrogenovibriomarinus) |
PF01058(Oxidored_q6)PF14720(NiFe_hyd_SSU_C) | 4 | ALA B 122GLU B 82ALA B 80MET B 165 | NoneF4S B 301 ( 4.8A)NoneNone | 1.45A | 3r9tC-3ayxB:undetectable | 3r9tC-3ayxB:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cqc | NUCLEAR PORE COMPLEXPROTEIN NUP133 (Homo sapiens) |
no annotation | 4 | ALA B 951GLU B 947ALA B 978MET B 987 | None | 1.22A | 3r9tC-3cqcB:undetectable | 3r9tC-3cqcB:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ddd | PUTATIVEACETYLTRANSFERASE (Pyrococcushorikoshii) |
PF00583(Acetyltransf_1) | 4 | ALA A 199GLU A 182GLU A 184ALA A 181 | None | 1.39A | 3r9tC-3dddA:undetectable | 3r9tC-3dddA:25.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dqz | ALPHA-HYDROXYNITRILELYASE-LIKE PROTEIN (Arabidopsisthaliana) |
PF12697(Abhydrolase_6) | 4 | ALA A 40GLU A 57ALA A 51MET A 144 | None | 1.05A | 3r9tC-3dqzA:2.4 | 3r9tC-3dqzA:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e13 | PUTATIVE IRON-UPTAKEABC TRANSPORTSYSTEM,PERIPLASMICIRON-BINDING PROTEIN (Campylobacterjejuni) |
PF13343(SBP_bac_6) | 4 | ALA X 129GLU X 162GLU X 126ALA X 165 | None | 1.47A | 3r9tC-3e13X:undetectable | 3r9tC-3e13X:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fvb | BACTERIOFERRITIN (Brucellaabortus) |
PF00210(Ferritin) | 4 | ALA A 21GLU A 127GLU A 94ALA A 97 | IMD A 171 (-3.4A) FE A 164 ( 2.5A)IMD A 171 (-3.2A)IMD A 171 (-3.4A) | 1.31A | 3r9tC-3fvbA:undetectable | 3r9tC-3fvbA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gvy | BACTERIOFERRITIN (Rhodobactersphaeroides) |
PF00210(Ferritin) | 4 | ALA A 93GLU A 51GLU A 127ALA A 21 | None FE A 163 (-2.5A) FE A 163 (-2.0A)None | 1.43A | 3r9tC-3gvyA:undetectable | 3r9tC-3gvyA:21.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3kqf | ENOYL-COAHYDRATASE/ISOMERASEFAMILY PROTEIN (Bacillusanthracis) |
PF00378(ECH_1) | 4 | ALA A 68GLU A 116GLU A 136ALA A 145 | None | 0.42A | 3r9tC-3kqfA:28.0 | 3r9tC-3kqfA:34.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kxw | SAFRAMYCIN MX1SYNTHETASE B (Legionellapneumophila) |
PF00501(AMP-binding) | 4 | ALA A 268GLU A 534GLU A 297MET A 219 | NoneNoneNone1ZZ A 589 ( 3.9A) | 1.09A | 3r9tC-3kxwA:undetectable | 3r9tC-3kxwA:18.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lad | DIHYDROLIPOAMIDEDEHYDROGENASE (Azotobactervinelandii) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | ALA A 242GLU A 262GLU A 264ALA A 261 | None | 1.35A | 3r9tC-3ladA:undetectable | 3r9tC-3ladA:23.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m3m | GLUTATHIONES-TRANSFERASE (Pseudomonasprotegens) |
PF00043(GST_C)PF13417(GST_N_3) | 4 | ALA A 164GLU A 103GLU A 98ALA A 107 | NoneGSH A 209 ( 4.9A)NoneNone | 1.40A | 3r9tC-3m3mA:undetectable | 3r9tC-3m3mA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mdu | N-FORMIMINO-L-GLUTAMATE IMINOHYDROLASE (Pseudomonasaeruginosa) |
PF01979(Amidohydro_1) | 4 | ALA A 144GLU A 118ALA A 59MET A 108 | GOL A 457 ( 4.2A)NoneNoneNone | 1.41A | 3r9tC-3mduA:undetectable | 3r9tC-3mduA:24.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n6r | PROPIONYL-COACARBOXYLASE, BETASUBUNIT (Roseobacterdenitrificans) |
PF01039(Carboxyl_trans) | 4 | ALA B 461GLU B 487GLU B 459ALA B 465 | None | 1.30A | 3r9tC-3n6rB:12.9 | 3r9tC-3n6rB:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nx3 | ACETYLORNITHINEAMINOTRANSFERASE (Campylobacterjejuni) |
PF00202(Aminotran_3) | 4 | ALA A 197GLU A 220ALA A 233MET A 335 | None | 1.38A | 3r9tC-3nx3A:undetectable | 3r9tC-3nx3A:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ogh | PROTEIN YCIE (Escherichiacoli) |
no annotation | 4 | GLU B 107GLU B 104ALA B 21MET B 28 | MG B 501 ( 2.4A) FE B 401 (-2.2A) MG B 501 ( 4.5A)None | 1.48A | 3r9tC-3oghB:undetectable | 3r9tC-3oghB:23.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qd8 | PROBABLEBACTERIOFERRITINBFRB (Mycobacteriumtuberculosis) |
PF00210(Ferritin) | 4 | ALA A 167GLU A 131GLU A 54ALA A 170 | None | 1.36A | 3r9tC-3qd8A:undetectable | 3r9tC-3qd8A:23.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3r0o | CARNITINYL-COADEHYDRATASE (Mycobacteriumavium) |
PF00378(ECH_1) | 4 | ALA A 73GLU A 120GLU A 140ALA A 149 | None | 0.52A | 3r9tC-3r0oA:43.3 | 3r9tC-3r0oA:75.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3r9s | CARNITINYL-COADEHYDRATASE (Mycobacteriumavium) |
PF00378(ECH_1) | 5 | ALA A 67GLU A 114GLU A 134ALA A 143MET A 236 | BEZ A 264 ( 3.7A)BEZ A 264 (-2.6A)BEZ A 264 (-3.3A)BEZ A 264 (-3.5A)None | 0.58A | 3r9tC-3r9sA:45.3 | 3r9tC-3r9sA:99.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uz0 | STAGE IIISPORULATION PROTEINAH (Bacillussubtilis) |
PF12685(SpoIIIAH) | 4 | ALA A 141GLU A 137GLU A 140ALA A 133 | None | 1.43A | 3r9tC-3uz0A:undetectable | 3r9tC-3uz0A:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4am2 | BACTERIOFERRITIN (Blastochlorisviridis) |
PF00210(Ferritin) | 4 | ALA A 93GLU A 51GLU A 127ALA A 21 | None FE A1161 ( 2.4A) FE A1161 ( 2.6A)None | 1.38A | 3r9tC-4am2A:undetectable | 3r9tC-4am2A:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f0l | AMIDOHYDROLASE (Brucellaabortus) |
PF01979(Amidohydro_1) | 4 | ALA A 149GLU A 123ALA A 64MET A 113 | None | 1.42A | 3r9tC-4f0lA:undetectable | 3r9tC-4f0lA:23.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4fzw | 2,3-DEHYDROADIPYL-COA HYDRATASE (Escherichiacoli) |
PF00378(ECH_1) | 4 | ALA A 63GLU A 109GLU A 129ALA A 138 | GOL A 301 ( 4.4A)GOL A 301 (-3.8A)GOL A 301 (-4.0A)GOL A 301 ( 4.6A) | 0.68A | 3r9tC-4fzwA:28.8 | 3r9tC-4fzwA:37.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gd3 | HYDROGENASE-1 SMALLCHAIN (Escherichiacoli) |
no annotation | 4 | ALA S 116GLU S 76ALA S 74MET S 156 | None | 1.41A | 3r9tC-4gd3S:undetectable | 3r9tC-4gd3S:23.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hz2 | GLUTATHIONES-TRANSFERASE DOMAIN (Xanthobacterautotrophicus) |
PF00043(GST_C)PF13417(GST_N_3) | 4 | ALA A 163GLU A 102GLU A 97ALA A 106 | NoneUNL A 303 ( 4.9A)NoneUNL A 303 ( 4.1A) | 1.34A | 3r9tC-4hz2A:undetectable | 3r9tC-4hz2A:24.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kvs | ALDEHYDEDECARBONYLASE (Prochlorococcusmarinus) |
PF11266(Ald_deCOase) | 4 | ALA A 131GLU A 73GLU A 45ALA A 48 | 6NA A 301 (-3.5A) FE A 303 (-2.4A) FE A 302 ( 2.4A)6NA A 301 (-3.5A) | 1.24A | 3r9tC-4kvsA:undetectable | 3r9tC-4kvsA:23.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mif | PYRANOSE 2-OXIDASE (Phanerochaetechrysosporium) |
PF05199(GMC_oxred_C) | 4 | ALA A 145GLU A 385GLU A 146ALA A 551 | None | 1.21A | 3r9tC-4mifA:undetectable | 3r9tC-4mifA:18.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4poo | PUTATIVE RNAMETHYLASE (Bacillussubtilis) |
PF06962(rRNA_methylase) | 4 | ALA A 185GLU A 187ALA A 17MET A 130 | None | 1.28A | 3r9tC-4pooA:undetectable | 3r9tC-4pooA:24.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ppm | AMINOTRANSFERASE (Serratia sp.FS14) |
PF00202(Aminotran_3) | 4 | ALA A 510GLU A 508ALA A 537MET A 557 | None | 1.14A | 3r9tC-4ppmA:undetectable | 3r9tC-4ppmA:18.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qor | CATALASE (Bacilluspumilus) |
PF00199(Catalase)PF06628(Catalase-rel) | 4 | ALA A 61GLU A 106ALA A 243MET A 194 | None | 1.36A | 3r9tC-4qorA:undetectable | 3r9tC-4qorA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r6l | BACTERIOPHYTOCHROME(LIGHT-REGULATEDSIGNAL TRANSDUCTIONHISTIDINE KINASE),PHYB1 (Rhodopseudomonaspalustris) |
PF00360(PHY)PF01590(GAF)PF08446(PAS_2) | 4 | ALA A 154GLU A 158GLU A 161ALA A 138 | None | 1.49A | 3r9tC-4r6lA:undetectable | 3r9tC-4r6lA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rc6 | ALDEHYDEDECARBONYLASE (Synechococcuselongatus) |
PF11266(Ald_deCOase) | 4 | ALA B 118GLU B 60GLU B 32ALA B 35 | NoneFE2 B 301 ( 2.3A)FE2 B 302 (-2.2A)FE2 B 301 ( 4.3A) | 1.20A | 3r9tC-4rc6B:undetectable | 3r9tC-4rc6B:24.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4toc | BACTERIOFERRITIN (Pseudomonasaeruginosa) |
PF00210(Ferritin) | 4 | ALA A 97GLU A 51GLU A 18ALA A 21 | NoneFE2 A 203 ( 2.2A)FE2 A 203 (-2.1A)None | 1.16A | 3r9tC-4tocA:undetectable | 3r9tC-4tocA:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4v1y | ATRAZINECHLOROHYDROLASE (Pseudomonas sp.ADP) |
PF01979(Amidohydro_1) | 4 | ALA A 153GLU A 125ALA A 130MET A 140 | None | 1.21A | 3r9tC-4v1yA:undetectable | 3r9tC-4v1yA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wxw | UNCHARACTERIZEDPROTEIN (Pseudomonasaeruginosa) |
PF00990(GGDEF) | 4 | ALA A 414GLU A 483GLU A 418ALA A 480 | None | 1.16A | 3r9tC-4wxwA:undetectable | 3r9tC-4wxwA:26.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a4m | HYDROGENASE-1 SMALLCHAIN (Escherichiacoli) |
PF01058(Oxidored_q6)PF14720(NiFe_hyd_SSU_C) | 4 | ALA S 116GLU S 76ALA S 74MET S 156 | NoneSF3 S 404 ( 4.7A)NoneNone | 1.42A | 3r9tC-5a4mS:undetectable | 3r9tC-5a4mS:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e0c | CELLULASE (Bacillus sp.BG-CS10) |
PF00150(Cellulase)PF03442(CBM_X2) | 4 | ALA A 122GLU A 119ALA A 71MET A 68 | None | 1.28A | 3r9tC-5e0cA:undetectable | 3r9tC-5e0cA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hzw | MALTOSE-BINDINGPERIPLASMICPROTEIN,ENDOGLIN (Escherichiacoli;Homo sapiens) |
PF13416(SBP_bac_8) | 4 | ALA A 727GLU A 617ALA A 643MET A 669 | None | 1.31A | 3r9tC-5hzwA:undetectable | 3r9tC-5hzwA:16.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5im3 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (Pseudomonasaeruginosa) |
PF00317(Ribonuc_red_lgN)PF02867(Ribonuc_red_lgC)PF03477(ATP-cone) | 4 | ALA A 339GLU A 338ALA A 331MET A 324 | None | 1.15A | 3r9tC-5im3A:2.2 | 3r9tC-5im3A:15.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j49 | UTP--GLUCOSE-1-PHOSPHATEURIDYLYLTRANSFERASE (Paraburkholderiaxenovorans) |
PF00483(NTP_transferase) | 4 | ALA A 48GLU A 44ALA A 128MET A 53 | None | 1.34A | 3r9tC-5j49A:undetectable | 3r9tC-5j49A:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j84 | DIHYDROXY-ACIDDEHYDRATASE (Rhizobiumleguminosarum) |
PF00920(ILVD_EDD) | 4 | ALA A 210GLU A 214ALA A 225MET A 236 | None | 1.18A | 3r9tC-5j84A:3.5 | 3r9tC-5j84A:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k52 | ALDEHYDEDECARBONYLASE (Limnothrix sp.KNUA012) |
PF11266(Ald_deCOase) | 4 | ALA A 118GLU A 60GLU A 32ALA A 35 | OCD A 500 (-3.6A)OCD A 500 (-3.2A)OCD A 500 (-3.5A)OCD A 500 ( 4.4A) | 1.37A | 3r9tC-5k52A:undetectable | 3r9tC-5k52A:23.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k53 | ALDEHYDEDEFORMYLATINGOXYGENASE (Oscillatoriasp.) |
PF11266(Ald_deCOase) | 4 | ALA A 118GLU A 60GLU A 32ALA A 35 | STE A 502 ( 3.9A) FE A 501 (-2.5A) FE A 500 ( 2.3A)STE A 502 (-3.5A) | 1.29A | 3r9tC-5k53A:undetectable | 3r9tC-5k53A:23.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kd5 | METALLOPEPTIDASE (Bacteroidesthetaiotaomicron) |
PF13402(Peptidase_M60)PF17291(M60-like_N) | 4 | ALA A 811GLU A 813ALA A 751MET A 709 | None | 1.21A | 3r9tC-5kd5A:undetectable | 3r9tC-5kd5A:18.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mdj | UPTAKE HYDROGENASESMALL SUBUNIT HOXK (Cupriavidusnecator) |
no annotation | 4 | ALA S 116GLU S 76ALA S 74MET S 156 | NoneF4S S1003 (-4.1A)NoneNone | 1.48A | 3r9tC-5mdjS:undetectable | 3r9tC-5mdjS:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mrw | POTASSIUM-TRANSPORTING ATPASEPOTASSIUM-BINDINGSUBUNIT (Escherichiacoli) |
PF03814(KdpA) | 4 | ALA A 459GLU A 455ALA A 444MET A 436 | None | 1.39A | 3r9tC-5mrwA:undetectable | 3r9tC-5mrwA:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n3u | PHYCOCYANOBILINLYASE SUBUNIT ALPHA (Nostoc sp. PCC7120) |
no annotation | 4 | ALA A 220GLU A 113GLU A 153ALA A 157 | None | 1.39A | 3r9tC-5n3uA:undetectable | 3r9tC-5n3uA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tir | SUPEROXIDE DISMUTASE (Trichodermareesei) |
no annotation | 4 | ALA A 103GLU A 194GLU A 100ALA A 98 | None | 1.06A | 3r9tC-5tirA:undetectable | 3r9tC-5tirA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ux2 | ALDEHYDEDECARBONYLASE (Synechococcussp. RS9917) |
no annotation | 4 | ALA A 112GLU A 54GLU A 26ALA A 29 | PPI A 303 ( 3.7A) FE A 301 (-2.5A) FE A 302 ( 2.1A)PPI A 303 ( 3.7A) | 1.30A | 3r9tC-5ux2A:undetectable | 3r9tC-5ux2A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wyb | PROBABLE ENOYL-COAHYDRATASE/ISOMERASE (Pseudomonasaeruginosa) |
no annotation | 4 | ALA B 78GLU B 126GLU B 146ALA B 155 | MRD B 301 (-3.1A)MRD B 301 (-2.8A)MRD B 301 (-2.5A)MRD B 301 (-4.2A) | 0.66A | 3r9tC-5wybB:28.8 | 3r9tC-5wybB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xf7 | PROTEINDISULFIDE-ISOMERASE-LIKE PROTEIN OF THETESTIS (Homo sapiens) |
no annotation | 4 | ALA A 85GLU A 140GLU A 81ALA A 143 | None | 1.33A | 3r9tC-5xf7A:undetectable | 3r9tC-5xf7A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xoy | [LYSW]-LYSINEHYDROLASE (Thermusthermophilus) |
PF01546(Peptidase_M20) | 4 | ALA A 121GLU A 148ALA A 92MET A 99 | None | 1.49A | 3r9tC-5xoyA:undetectable | 3r9tC-5xoyA:25.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yix | RNA POLYMERASE SIGMAFACTOR RPOD (Caulobactervibrioides) |
no annotation | 4 | ALA A 415GLU A 411ALA A 143MET A 148 | None | 1.31A | 3r9tC-5yixA:undetectable | 3r9tC-5yixA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zrz | EPHRIN TYPE-ARECEPTOR 5 (Mus musculus) |
no annotation | 4 | ALA A 815GLU A 811ALA A 805MET A 833 | None | 1.10A | 3r9tC-5zrzA:undetectable | 3r9tC-5zrzA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6anv | ANTI-CRISPR PROTEINACRF1 FUSED WITHC-TERMINAL MBP TAG (Escherichiacoli;Pseudomonasphage JBD30) |
no annotation | 4 | ALA A 41GLU A 31ALA A 18MET A 1 | MES A 502 (-4.6A)NoneNonePEG A 509 ( 4.2A) | 1.29A | 3r9tC-6anvA:undetectable | 3r9tC-6anvA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cy1 | SIGNAL RECOGNITIONPARTICLE RECEPTORFTSY (Elizabethkingiaanophelis) |
no annotation | 4 | ALA A 182GLU A 217ALA A 150MET A 118 | None | 1.19A | 3r9tC-6cy1A:undetectable | 3r9tC-6cy1A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fv4 | N-ACETYLGLUCOSAMINE-6-PHOSPHATEDEACETYLASE (Mycolicibacteriumsmegmatis) |
no annotation | 4 | ALA A 213GLU A 122ALA A 133MET A 139 | 16G A 402 (-4.6A) CD A 403 (-2.4A)16G A 402 (-3.8A)None | 1.17A | 3r9tC-6fv4A:undetectable | 3r9tC-6fv4A:undetectable |