SIMILAR PATTERNS OF AMINO ACIDS FOR 3R9T_A_BEZA264

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a05 3-ISOPROPYLMALATE
DEHYDROGENASE

(Acidithiobacillus
ferrooxidans) 		PF00180
(Iso_dh) 		4 ILE A 170
LEU A 239
ALA A 177
ALA A 178
 None
 0.72A 3r9tA-1a05A:
undetectable		 3r9tA-1a05A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)

(Bacillus
subtilis) 		PF00135
(COesterase) 		4 ALA A 297
ILE A 292
ALA A 211
MET A 213
 None
 0.71A 3r9tA-1c7jA:
undetectable		 3r9tA-1c7jA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d1j PROFILIN II

(Homo sapiens) 		PF00235
(Profilin) 		4 GLU A  18
ALA A  19
ALA A  20
MET A  11
 None
 0.76A 3r9tA-1d1jA:
undetectable		 3r9tA-1d1jA:
22.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1dub 2-ENOYL-COA
HYDRATASE

(Rattus
norvegicus) 		PF00378
(ECH_1) 		4 ALA A  98
GLU A 144
GLU A 164
ALA A 173
 CAA  A 300 (-3.6A)
CAA  A 300 ( 3.0A)
CAA  A 300 ( 3.5A)
CAA  A 300 ( 4.7A)
 0.32A 3r9tA-1dubA:
26.7		 3r9tA-1dubA:
36.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fw8 PHOSPHOGLYCERATE
KINASE

(Saccharomyces
cerevisiae) 		PF00162
(PGK) 		5 ILE A 161
LEU A 135
GLU A 284
ALA A 252
ALA A 255
 None
 1.19A 3r9tA-1fw8A:
undetectable		 3r9tA-1fw8A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g67 THIAMIN PHOSPHATE
SYNTHASE

(Bacillus
subtilis) 		PF02581
(TMP-TENI) 		4 ILE A 108
LEU A 127
GLU A 117
ALA A 121
 None
 0.70A 3r9tA-1g67A:
undetectable		 3r9tA-1g67A:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m7t CHIMERA OF HUMAN AND
E. COLI THIOREDOXIN

(Escherichia
coli;
Homo sapiens) 		PF00085
(Thioredoxin) 		4 ILE A   5
LEU A  55
ALA A  17
ALA A  18
 None
 0.74A 3r9tA-1m7tA:
undetectable		 3r9tA-1m7tA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mqv CYTOCHROME C'

(Rhodopseudomonas
palustris) 		PF01322
(Cytochrom_C_2) 		4 ILE A  22
LEU A 110
ALA A  89
ALA A  88
 None
 0.69A 3r9tA-1mqvA:
undetectable		 3r9tA-1mqvA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mvo PHOP RESPONSE
REGULATOR

(Bacillus
subtilis) 		PF00072
(Response_reg) 		4 ILE A  62
LEU A  91
ALA A  97
MET A  79
 None
 0.75A 3r9tA-1mvoA:
undetectable		 3r9tA-1mvoA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n60 CARBON MONOXIDE
DEHYDROGENASE LARGE
CHAIN

(Oligotropha
carboxidovorans) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 ALA B 521
ILE B 551
ALA B 584
ALA B 583
 None
 0.68A 3r9tA-1n60B:
undetectable		 3r9tA-1n60B:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n7k DEOXYRIBOSE-PHOSPHAT
E ALDOLASE

(Aeropyrum
pernix) 		PF01791
(DeoC) 		4 ALA A  68
ILE A  64
LEU A  75
ALA A  46
 None
 0.68A 3r9tA-1n7kA:
undetectable		 3r9tA-1n7kA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nvm 4-HYDROXY-2-OXOVALER
ATE ALDOLASE

(Pseudomonas sp.
CF600) 		PF00682
(HMGL-like)
PF07836
(DmpG_comm) 		5 ALA A  36
ILE A  47
LEU A  16
GLU A  79
ALA A  75
 None
 1.33A 3r9tA-1nvmA:
undetectable		 3r9tA-1nvmA:
24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nye OSMOTICALLY
INDUCIBLE PROTEIN C

(Escherichia
coli) 		PF02566
(OsmC) 		5 ALA A 102
ILE A 118
LEU A 120
ALA A  75
ALA A  78
 None
 1.38A 3r9tA-1nyeA:
undetectable		 3r9tA-1nyeA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)

(Homo sapiens) 		PF03810
(IBN_N)
PF13513
(HEAT_EZ) 		5 ALA A 818
ILE A 801
LEU A 846
ALA A 865
ALA A 862
 None
 1.23A 3r9tA-1qgrA:
undetectable		 3r9tA-1qgrA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qwi OSMOTICALLY
INDUCIBLE PROTEIN

(Escherichia
coli) 		PF02566
(OsmC) 		5 ALA A  82
ILE A  98
LEU A 100
ALA A  55
ALA A  58
 None
 1.38A 3r9tA-1qwiA:
undetectable		 3r9tA-1qwiA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vpb PUTATIVE MODULATOR
OF DNA GYRASE

(Bacteroides
thetaiotaomicron) 		PF01523
(PmbA_TldD) 		4 ALA A 140
ILE A 147
LEU A 218
ALA A 182
 None
 0.75A 3r9tA-1vpbA:
undetectable		 3r9tA-1vpbA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ydn HYDROXYMETHYLGLUTARY
L-COA LYASE

(Brucella
melitensis) 		PF00682
(HMGL-like) 		4 ALA A 129
ILE A 136
ALA A  88
ALA A  89
 None
 0.68A 3r9tA-1ydnA:
2.4		 3r9tA-1ydnA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z9d URIDYLATE KINASE

(Streptococcus
pyogenes) 		PF00696
(AA_kinase) 		4 ALA A 162
ILE A  12
ALA A  18
MET A  89
 None
 0.69A 3r9tA-1z9dA:
undetectable		 3r9tA-1z9dA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bjo ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
OHRB

(Bacillus
subtilis) 		PF02566
(OsmC) 		4 ALA A  64
ILE A  71
ALA A 115
ALA A 114
 None
 0.70A 3r9tA-2bjoA:
undetectable		 3r9tA-2bjoA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ehq 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE

(Thermus
thermophilus) 		PF00171
(Aldedh) 		4 ALA A  71
LEU A  40
ALA A  78
ALA A  79
 None
 0.76A 3r9tA-2ehqA:
undetectable		 3r9tA-2ehqA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fre NAD(P)H-FLAVIN
OXIDOREDUCTASE

(Agrobacterium
fabrum) 		PF00881
(Nitroreductase) 		4 ALA A 125
ILE A 161
ALA A  43
ALA A  42
 None
 0.66A 3r9tA-2freA:
undetectable		 3r9tA-2freA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fus FUMARASE C

(Escherichia
coli) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		4 ALA A  77
LEU A 110
ALA A  55
ALA A  56
 None
 0.63A 3r9tA-2fusA:
undetectable		 3r9tA-2fusA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2giy GLYCOPROTEIN E

(Human
alphaherpesvirus
1) 		PF02480
(Herpes_gE) 		4 ALA A 384
ILE A 276
LEU A 356
ALA A 231
 None
 0.69A 3r9tA-2giyA:
undetectable		 3r9tA-2giyA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gj7 GLYCOPROTEIN E

(Human
alphaherpesvirus
1) 		no annotation 4 ALA F 384
ILE F 276
LEU F 356
ALA F 231
 None
 0.69A 3r9tA-2gj7F:
undetectable		 3r9tA-2gj7F:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gl5 PUTATIVE DEHYDRATASE
PROTEIN

(Salmonella
enterica) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ILE A 206
ALA A 156
ALA A 155
MET A 213
 None
 0.58A 3r9tA-2gl5A:
1.5		 3r9tA-2gl5A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hfe KCSA CHANNEL
KCSA CHANNEL

(Streptomyces
coelicolor;
Streptomyces
coelicolor) 		no annotation
PF07885
(Ion_trans_2) 		4 ALA C  28
LEU C  24
ALA D 108
ALA D 109
 None
 0.70A 3r9tA-2hfeC:
undetectable		 3r9tA-2hfeC:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jsw TALIN-1

(Mus musculus) 		PF01608
(I_LWEQ) 		4 ALA A2363
LEU A2359
ALA A2396
ALA A2397
 None
 0.75A 3r9tA-2jswA:
undetectable		 3r9tA-2jswA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l3u YBBR FAMILY PROTEIN

(Desulfitobacterium
hafniense) 		no annotation 4 ALA A  33
ILE A  31
LEU A  38
ALA A  70
 None
 0.62A 3r9tA-2l3uA:
undetectable		 3r9tA-2l3uA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nty EMB|CAB41934.1

(Arabidopsis
thaliana) 		PF03759
(PRONE) 		4 ALA A 341
LEU A 124
ALA A 192
ALA A 193
 None
 0.76A 3r9tA-2ntyA:
undetectable		 3r9tA-2ntyA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p1z PHOSPHORIBOSYLTRANSF
ERASE

(Corynebacterium
diphtheriae) 		PF00156
(Pribosyltran) 		4 ALA A  44
ILE A  48
LEU A   7
ALA A  15
 None
 0.72A 3r9tA-2p1zA:
undetectable		 3r9tA-2p1zA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pvz PRPF METHYLACONITATE
ISOMERASE

(Shewanella
oneidensis) 		PF04303
(PrpF) 		4 ALA A 220
ILE A 218
ALA A 364
ALA A 378
 None
 0.74A 3r9tA-2pvzA:
undetectable		 3r9tA-2pvzA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q5o PHENYLPYRUVATE
DECARBOXYLASE

(Azospirillum
brasilense) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 ALA A 141
ILE A 145
LEU A 135
ALA A 170
 None
 0.68A 3r9tA-2q5oA:
undetectable		 3r9tA-2q5oA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Roseovarius
nubinhibens) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ALA A 343
ILE A 135
ALA A 308
ALA A 309
 None
 0.63A 3r9tA-2qddA:
3.7		 3r9tA-2qddA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qna IMPORTIN SUBUNIT
BETA-1

(Homo sapiens) 		PF13513
(HEAT_EZ) 		5 ALA A 818
ILE A 801
LEU A 846
ALA A 865
ALA A 862
 None
 1.08A 3r9tA-2qnaA:
undetectable		 3r9tA-2qnaA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qzw CANDIDAPEPSIN-1

(Candida
albicans) 		PF00026
(Asp) 		4 ALA A 112
ILE A 114
ALA A 133
ALA A 134
 None
 0.71A 3r9tA-2qzwA:
undetectable		 3r9tA-2qzwA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uv8 FATTY ACID SYNTHASE
SUBUNIT BETA (FAS1)

(Saccharomyces
cerevisiae) 		PF00698
(Acyl_transf_1)
PF01575
(MaoC_dehydratas)
PF08354
(DUF1729)
PF13452
(MaoC_dehydrat_N)
PF16073
(SAT) 		4 ALA G 923
ILE G 980
LEU G 951
ALA G 990
 None
 0.64A 3r9tA-2uv8G:
undetectable		 3r9tA-2uv8G:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v28 PHENYLALANINE-4-HYDR
OXYLASE

(Colwellia
psychrerythraea) 		PF00351
(Biopterin_H) 		4 ALA A 194
ILE A 179
LEU A 170
GLU A 190
 None
 0.76A 3r9tA-2v28A:
undetectable		 3r9tA-2v28A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x58 PEROXISOMAL
BIFUNCTIONAL ENZYME

(Rattus
norvegicus) 		PF00378
(ECH_1)
PF00725
(3HCDH)
PF02737
(3HCDH_N) 		4 ALA A  61
GLU A 103
GLU A 123
ALA A 132
 GOL  A 770 (-4.1A)
GOL  A 770 (-2.9A)
GOL  A 770 ( 3.5A)
GOL  A 770 (-3.8A)
 0.35A 3r9tA-2x58A:
20.3		 3r9tA-2x58A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zwv PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE

(Thermus
thermophilus) 		PF05175
(MTS) 		4 ALA A 152
LEU A 173
ALA A 125
ALA A 126
 None
 0.53A 3r9tA-2zwvA:
undetectable		 3r9tA-2zwvA:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a8k AMINOMETHYLTRANSFERA
SE

(Escherichia
coli) 		PF01571
(GCV_T)
PF08669
(GCV_T_C) 		4 ALA A 155
ILE A 196
LEU A 210
ALA A  43
 None
 0.75A 3r9tA-3a8kA:
undetectable		 3r9tA-3a8kA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b9e CHITINASE A

(Vibrio harveyi) 		PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N) 		4 ILE A 364
LEU A 444
ALA A 377
MET A 383
 None
 0.66A 3r9tA-3b9eA:
undetectable		 3r9tA-3b9eA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bq9 PREDICTED ROSSMANN
FOLD
NUCLEOTIDE-BINDING
DOMAIN-CONTAINING
PROTEIN

(Idiomarina
baltica) 		PF03641
(Lysine_decarbox)
PF11892
(DUF3412)
PF14793
(DUF4478) 		4 ALA A  52
ILE A 401
ALA A 218
ALA A 217
 None
 0.71A 3r9tA-3bq9A:
undetectable		 3r9tA-3bq9A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cdx SUCCINYLGLUTAMATEDES
UCCINYLASE/ASPARTOAC
YLASE

(Rhodobacter
sphaeroides) 		PF04952
(AstE_AspA) 		4 ALA A 271
ILE A 296
LEU A 309
ALA A 321
 None
 0.69A 3r9tA-3cdxA:
undetectable		 3r9tA-3cdxA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ce6 ADENOSYLHOMOCYSTEINA
SE

(Mycobacterium
tuberculosis) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		4 ALA A 160
ILE A 153
LEU A 141
ALA A  91
 None
 0.72A 3r9tA-3ce6A:
undetectable		 3r9tA-3ce6A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cnu PREDICTED CODING
REGION AF_1534

(Archaeoglobus
fulgidus) 		PF02036
(SCP2) 		4 ALA A   4
ILE A   8
LEU A  76
ALA A  67
 None
 0.72A 3r9tA-3cnuA:
undetectable		 3r9tA-3cnuA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ew5 MACRO DOMAIN OF
NON-STRUCTURAL
PROTEIN 3

(Alphacoronavirus
1) 		PF01661
(Macro) 		4 ILE A 145
LEU A 122
ALA A  67
ALA A  68
 None
None
1GP  A   9 (-3.4A)
None
 0.73A 3r9tA-3ew5A:
undetectable		 3r9tA-3ew5A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fhh OUTER MEMBRANE HEME
RECEPTOR SHUA

(Shigella
dysenteriae) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		4 ALA A 170
ILE A 168
LEU A 197
ALA A  95
 None
 0.73A 3r9tA-3fhhA:
undetectable		 3r9tA-3fhhA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hko CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 2
CALMODULIN-LIKE EF
HANDS

(Cryptosporidium
parvum) 		PF00069
(Pkinase) 		5 ALA A 310
ILE A 316
LEU A 292
ALA A 244
ALA A 241
 None
 1.24A 3r9tA-3hkoA:
undetectable		 3r9tA-3hkoA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hra ANKYRIN REPEAT
FAMILY PROTEIN

(Enterococcus
faecalis) 		PF12796
(Ank_2)
PF13857
(Ank_5) 		4 ALA A  55
ILE A  59
LEU A  43
ALA A  79
 None
 0.70A 3r9tA-3hraA:
undetectable		 3r9tA-3hraA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3icj UNCHARACTERIZED
METAL-DEPENDENT
HYDROLASE

(Pyrococcus
furiosus) 		PF07969
(Amidohydro_3) 		4 ALA A 265
ILE A 290
LEU A 267
ALA A 246
 None
 0.68A 3r9tA-3icjA:
3.0		 3r9tA-3icjA:
19.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3kqf ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN

(Bacillus
anthracis) 		PF00378
(ECH_1) 		4 ALA A  68
GLU A 116
GLU A 136
ALA A 145
 None
 0.41A 3r9tA-3kqfA:
28.0		 3r9tA-3kqfA:
34.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lqy PUTATIVE
ISOCHORISMATASE
HYDROLASE

(Oleispira
antarctica) 		PF00857
(Isochorismatase) 		4 ALA A 120
LEU A  29
ALA A  36
ALA A  35
 None
 0.61A 3r9tA-3lqyA:
undetectable		 3r9tA-3lqyA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n5a SYNAPTOTAGMIN-7

(Mus musculus) 		PF00168
(C2) 		4 ILE A 370
LEU A 272
GLU A 269
ALA A 290
 None
 0.68A 3r9tA-3n5aA:
undetectable		 3r9tA-3n5aA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nu8 AMINOTRANSFERASE
WBPE

(Pseudomonas
aeruginosa) 		PF01041
(DegT_DnrJ_EryC1) 		4 ALA A  62
ILE A 196
ALA A 157
ALA A 158
 None
None
None
LLP  A 185 ( 3.3A)
 0.76A 3r9tA-3nu8A:
undetectable		 3r9tA-3nu8A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oid ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADPH]

(Bacillus
subtilis) 		PF13561
(adh_short_C2) 		4 LEU A 168
GLU A 123
ALA A 124
ALA A 125
 None
 0.69A 3r9tA-3oidA:
undetectable		 3r9tA-3oidA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qn3 ENOLASE

(Campylobacter
jejuni) 		PF00113
(Enolase_C)
PF03952
(Enolase_N) 		4 ILE A 339
LEU A 133
ALA A 121
ALA A 122
 None
 0.54A 3r9tA-3qn3A:
undetectable		 3r9tA-3qn3A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qqc DNA-DIRECTED RNA
POLYMERASE SUBUNIT
B, DNA-DIRECTED RNA
POLYMERASE SUBUNIT
A', DNA-DIRECTED RNA
POLYMERASE SUBUNIT
A''

(Pyrococcus
furiosus) 		PF04560
(RNA_pol_Rpb2_7)
PF04997
(RNA_pol_Rpb1_1) 		4 ILE A 409
LEU A  51
ALA A 417
ALA A 418
 None
 0.75A 3r9tA-3qqcA:
undetectable		 3r9tA-3qqcA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qwb PROBABLE QUINONE
OXIDOREDUCTASE

(Saccharomyces
cerevisiae) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 ALA A 194
LEU A 197
ALA A 158
ALA A 157
 None
 0.69A 3r9tA-3qwbA:
undetectable		 3r9tA-3qwbA:
24.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3r0o CARNITINYL-COA
DEHYDRATASE

(Mycobacterium
avium) 		PF00378
(ECH_1) 		4 ALA A  73
GLU A 120
GLU A 140
ALA A 149
 None
 0.56A 3r9tA-3r0oA:
43.1		 3r9tA-3r0oA:
75.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3r9s CARNITINYL-COA
DEHYDRATASE

(Mycobacterium
avium) 		PF00378
(ECH_1) 		7 ALA A  67
ILE A  72
LEU A  78
GLU A 114
ALA A 142
ALA A 143
MET A 236
 BEZ  A 264 ( 3.7A)
None
None
BEZ  A 264 (-2.6A)
BEZ  A 264 (-4.2A)
BEZ  A 264 (-3.5A)
None
 0.57A 3r9tA-3r9sA:
45.4		 3r9tA-3r9sA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3r9s CARNITINYL-COA
DEHYDRATASE

(Mycobacterium
avium) 		PF00378
(ECH_1) 		7 ALA A  67
ILE A  72
LEU A  78
GLU A 114
GLU A 134
ALA A 142
ALA A 143
 BEZ  A 264 ( 3.7A)
None
None
BEZ  A 264 (-2.6A)
BEZ  A 264 (-3.3A)
BEZ  A 264 (-4.2A)
BEZ  A 264 (-3.5A)
 0.32A 3r9tA-3r9sA:
45.4		 3r9tA-3r9sA:
99.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rx8 CELLULASE

(Alicyclobacillus
acidocaldarius) 		PF00759
(Glyco_hydro_9)
PF02927
(CelD_N) 		4 ALA A 255
ILE A 198
ALA A 273
ALA A 274
 None
 0.69A 3r9tA-3rx8A:
undetectable		 3r9tA-3rx8A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sb4 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN

(Bacteroides
thetaiotaomicron) 		PF13306
(LRR_5) 		4 ILE A 132
GLU A 136
ALA A 139
ALA A 163
 None
 0.72A 3r9tA-3sb4A:
undetectable		 3r9tA-3sb4A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3umg HALOACID
DEHALOGENASE

(Rhodococcus
jostii) 		PF00702
(Hydrolase) 		4 ALA A 236
ILE A 212
ALA A 243
ALA A 244
 None
 0.75A 3r9tA-3umgA:
undetectable		 3r9tA-3umgA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v5n OXIDOREDUCTASE

(Sinorhizobium
meliloti) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 ALA A  36
LEU A  17
ALA A 346
ALA A 347
 None
 0.64A 3r9tA-3v5nA:
undetectable		 3r9tA-3v5nA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wxx ACRH
AOPB

(Aeromonas
hydrophila;
Aeromonas
hydrophila) 		no annotation
PF04888
(SseC) 		4 ALA B 188
ILE B 239
LEU A  17
ALA B 182
 None
 0.75A 3r9tA-3wxxB:
undetectable		 3r9tA-3wxxB:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4emb 2,3-BISPHOSPHOGLYCER
ATE-DEPENDENT
PHOSPHOGLYCERATE
MUTASE

(Borreliella
burgdorferi) 		PF00300
(His_Phos_1) 		5 ALA A 185
ILE A 183
LEU A  70
ALA A  44
ALA A  41
 None
 1.31A 3r9tA-4embA:
undetectable		 3r9tA-4embA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j0k TANNASE

(Lactobacillus
plantarum) 		no annotation 4 ALA A 129
ILE A 394
LEU A 360
ALA A 386
 None
 0.69A 3r9tA-4j0kA:
2.6		 3r9tA-4j0kA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j4s NUCLEOCAPSID PROTEIN

(SFTS
phlebovirus) 		PF05733
(Tenui_N) 		4 ILE A 224
LEU A 166
ALA A 238
ALA A 239
 None
 0.75A 3r9tA-4j4sA:
undetectable		 3r9tA-4j4sA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jwy GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2D

(Rattus
norvegicus) 		PF10613
(Lig_chan-Glu_bd) 		4 ALA A 248
ILE A 100
LEU A 115
ALA A  10
 None
None
1N4  A 301 ( 4.9A)
None
 0.73A 3r9tA-4jwyA:
undetectable		 3r9tA-4jwyA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l8k PUTATIVE PEPTIDASE

(Parabacteroides
merdae) 		PF03572
(Peptidase_S41)
PF14684
(Tricorn_C1) 		4 ILE A 308
GLU A 322
ALA A 323
ALA A 324
 None
 0.64A 3r9tA-4l8kA:
7.7		 3r9tA-4l8kA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mwa 4-HYDROXY-3-METHYLBU
T-2-EN-1-YL
DIPHOSPHATE SYNTHASE

(Bacillus
anthracis) 		PF04551
(GcpE) 		4 ALA D  92
ILE D 105
ALA D 123
ALA D 122
 None
 0.63A 3r9tA-4mwaD:
undetectable		 3r9tA-4mwaD:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nle ADENYLOSUCCINATE
LYASE

(Mycolicibacterium
smegmatis) 		PF00206
(Lyase_1)
PF10397
(ADSL_C) 		4 ALA A 136
ALA A 165
ALA A 166
MET A 255
 None
 0.70A 3r9tA-4nleA:
undetectable		 3r9tA-4nleA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nle ADENYLOSUCCINATE
LYASE

(Mycolicibacterium
smegmatis) 		PF00206
(Lyase_1)
PF10397
(ADSL_C) 		4 ALA A 389
ILE A 393
LEU A 423
ALA A 378
 None
 0.74A 3r9tA-4nleA:
undetectable		 3r9tA-4nleA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nrh COPN

(Chlamydia
pneumoniae) 		PF07201
(HrpJ) 		4 ALA A 123
ILE A 119
LEU A 160
ALA A 167
 None
 0.72A 3r9tA-4nrhA:
undetectable		 3r9tA-4nrhA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4opf NRPS/PKS

(Streptomyces
albus) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 ALA A6295
LEU A6288
ALA A6352
ALA A6351
 None
 0.72A 3r9tA-4opfA:
undetectable		 3r9tA-4opfA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p2b GLUTAMINE
AMINOACYL-TRNA
SYNTHETASE

(Toxoplasma
gondii) 		PF00749
(tRNA-synt_1c)
PF03950
(tRNA-synt_1c_C) 		4 ALA A 481
ILE A 483
ALA A 527
ALA A 528
 None
 0.57A 3r9tA-4p2bA:
undetectable		 3r9tA-4p2bA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uuj VOLTAGE-GATED
POTASSIUM CHANNEL
KCSA

(Streptomyces
lividans) 		PF07885
(Ion_trans_2) 		4 ALA C  28
LEU C  24
ALA C 108
ALA C 109
 None
 0.64A 3r9tA-4uujC:
undetectable		 3r9tA-4uujC:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w5k ASPARTATE
AMINOTRANSFERASE,
MITOCHONDRIAL

(Trypanosoma
brucei) 		PF00155
(Aminotran_1_2) 		4 ILE A 383
LEU A 316
ALA A 340
MET A 360
 None
 0.76A 3r9tA-4w5kA:
undetectable		 3r9tA-4w5kA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wji PUTATIVE
CYCLOHEXADIENYL
DEHYDROGENASE AND
ADH PREPHENATE
DEHYDROGENASE

(Sinorhizobium
meliloti) 		PF02153
(PDH) 		4 ALA A  21
ILE A  33
LEU A  10
ALA A  46
 None
 0.71A 3r9tA-4wjiA:
undetectable		 3r9tA-4wjiA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wxw UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		PF00990
(GGDEF) 		5 ALA A 414
LEU A 449
GLU A 483
GLU A 418
ALA A 480
 None
 1.12A 3r9tA-4wxwA:
undetectable		 3r9tA-4wxwA:
26.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wxw UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		PF00990
(GGDEF) 		5 ALA A 414
LEU A 449
GLU A 483
GLU A 418
ALA A 480
 None
 1.37A 3r9tA-4wxwA:
undetectable		 3r9tA-4wxwA:
26.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ysj CALMODULIN-LIKE
DOMAIN PROTEIN
KINASE

(Eimeria tenella) 		PF00069
(Pkinase)
PF13499
(EF-hand_7) 		5 ILE A 435
LEU A 440
ALA A 317
ALA A 318
MET A 477
 None
 1.34A 3r9tA-4ysjA:
undetectable		 3r9tA-4ysjA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b13 PHYCOERYTHRIN ALPHA
SUBUNIT

(Palmaria
palmata) 		PF00502
(Phycobilisome) 		5 ALA A 155
LEU A 156
GLU A 151
ALA A  40
MET A 144
 None
 1.47A 3r9tA-5b13A:
undetectable		 3r9tA-5b13A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b3g PROTEIN SHORT-ROOT

(Arabidopsis
thaliana) 		PF03514
(GRAS) 		4 LEU B 415
GLU B 149
ALA B 150
ALA B 151
 None
 0.53A 3r9tA-5b3gB:
undetectable		 3r9tA-5b3gB:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b3h PROTEIN SHORT-ROOT

(Arabidopsis
thaliana) 		PF03514
(GRAS) 		4 LEU B 415
GLU B 149
ALA B 150
ALA B 151
 None
 0.71A 3r9tA-5b3hB:
undetectable		 3r9tA-5b3hB:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cec BD3460

(Bdellovibrio
bacteriovorus) 		PF12796
(Ank_2) 		4 ALA B 112
ILE B 116
LEU B 100
ALA B 138
 None
 0.67A 3r9tA-5cecB:
undetectable		 3r9tA-5cecB:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cer BD3460

(Bdellovibrio
bacteriovorus) 		PF12796
(Ank_2) 		4 ALA B 112
ILE B 116
LEU B 100
ALA B 138
 None
 0.67A 3r9tA-5cerB:
undetectable		 3r9tA-5cerB:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cfn STIMULATOR OF
INTERFERON GENES

(Nematostella
vectensis) 		PF15009
(TMEM173) 		4 ALA A 302
ILE A 238
LEU A 305
ALA A 199
 None
 0.75A 3r9tA-5cfnA:
undetectable		 3r9tA-5cfnA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d66 UNCHARACTERIZED
PROTEIN

(Acinetobacter
baumannii) 		PF12796
(Ank_2) 		4 ALA A  90
ILE A  94
LEU A  78
ALA A 114
 None
 0.71A 3r9tA-5d66A:
undetectable		 3r9tA-5d66A:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5loi RAD26

(Thermothelomyces
thermophila) 		PF12331
(DUF3636) 		4 ALA A 434
ILE A 438
LEU A 460
ALA A 472
 None
 0.69A 3r9tA-5loiA:
undetectable		 3r9tA-5loiA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA

(Nostoc sp. PCC
7120) 		no annotation 5 ILE A 167
LEU A 189
GLU A 153
ALA A 154
ALA A 157
 None
 1.32A 3r9tA-5n3uA:
undetectable		 3r9tA-5n3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uhe DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA'

(Mycobacterium
tuberculosis) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		4 ALA D1236
ILE D  12
ALA D1224
ALA D1223
 None
 0.69A 3r9tA-5uheD:
undetectable		 3r9tA-5uheD:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vye L-THREONINE ALDOLASE

(Pseudomonas
putida) 		no annotation 4 ALA A 110
ILE A  83
LEU A 117
GLU A 124
 None
 0.61A 3r9tA-5vyeA:
undetectable		 3r9tA-5vyeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xfl CATENIN ALPHA-2

(Mus musculus) 		no annotation 4 ALA A 418
ILE A 463
ALA A 406
ALA A 405
 None
 0.69A 3r9tA-5xflA:
undetectable		 3r9tA-5xflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y35 -

(-) 		no annotation 4 ALA B 185
ILE B 183
LEU B 190
ALA B 163
 None
 0.71A 3r9tA-5y35B:
undetectable		 3r9tA-5y35B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ank SYNAPTOTAGMIN-7

(Rattus
norvegicus) 		PF00168
(C2) 		4 ILE A 370
LEU A 272
GLU A 269
ALA A 290
 None
 0.70A 3r9tA-6ankA:
undetectable		 3r9tA-6ankA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b5f NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE

(Yersinia
enterocolitica) 		no annotation 4 ILE A 276
LEU A   8
ALA A 253
ALA A 254
 None
 0.67A 3r9tA-6b5fA:
3.2		 3r9tA-6b5fA:
25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c0e ISOCITRATE
DEHYDROGENASE

(Legionella
pneumophila) 		no annotation 4 ALA A  76
ILE A  38
LEU A 109
ALA A 123
 None
 0.75A 3r9tA-6c0eA:
undetectable		 3r9tA-6c0eA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6epi ZETA_1 TOXIN

(Neisseria
gonorrhoeae) 		no annotation 5 ALA B 247
ILE B 250
LEU B 273
ALA B 344
ALA B 345
 None
 1.05A 3r9tA-6epiB:
undetectable		 3r9tA-6epiB:
undetectable