SIMILAR PATTERNS OF AMINO ACIDS FOR 3R9S_C_BEZC264_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)


(Escherichia
coli)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
4 ALA A 187
ILE A 170
LEU A 240
ALA A  84
None
0.86A 3r9sC-1b3nA:
undetectable
3r9sC-1b3nA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c8z TUBBY PROTEIN

(Mus musculus)
PF01167
(Tub)
4 ALA A 254
ILE A 328
LEU A 298
GLU A 252
None
0.87A 3r9sC-1c8zA:
undetectable
3r9sC-1c8zA:
23.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1dub 2-ENOYL-COA
HYDRATASE


(Rattus
norvegicus)
PF00378
(ECH_1)
4 ALA A  98
GLU A 144
GLU A 164
ALA A 173
CAA  A 300 (-3.6A)
CAA  A 300 ( 3.0A)
CAA  A 300 ( 3.5A)
CAA  A 300 ( 4.7A)
0.31A 3r9sC-1dubA:
25.9
3r9sC-1dubA:
36.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e2y TRYPAREDOXIN
PEROXIDASE


(Crithidia
fasciculata)
PF00578
(AhpC-TSA)
PF10417
(1-cysPrx_C)
4 ALA A  12
ILE A 133
LEU A  31
ALA A 115
None
0.83A 3r9sC-1e2yA:
undetectable
3r9sC-1e2yA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ee2 ALCOHOL
DEHYDROGENASE


(Equus caballus)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 ILE A 345
LEU A 170
GLU A 166
ALA A  70
None
0.89A 3r9sC-1ee2A:
undetectable
3r9sC-1ee2A:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1itk CATALASE-PEROXIDASE

(Haloarcula
marismortui)
PF00141
(peroxidase)
4 ALA A 611
ILE A 698
GLU A 613
ALA A  40
CL  A2002 ( 3.8A)
None
None
None
0.80A 3r9sC-1itkA:
undetectable
3r9sC-1itkA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j3m THE CONSERVED
HYPOTHETICAL PROTEIN
TT1751


(Thermus
thermophilus)
PF03625
(DUF302)
4 ALA A  65
ILE A  72
LEU A 111
ALA A 118
None
0.86A 3r9sC-1j3mA:
undetectable
3r9sC-1j3mA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l5z C4-DICARBOXYLATE
TRANSPORT
TRANSCRIPTIONAL
REGULATORY PROTEIN
DCTD


(Sinorhizobium
meliloti)
PF00072
(Response_reg)
4 ALA A 116
ILE A  53
LEU A 112
ALA A  27
None
0.90A 3r9sC-1l5zA:
undetectable
3r9sC-1l5zA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l8w VLSE1

(Borreliella
burgdorferi)
PF00921
(Lipoprotein_2)
4 ALA A 168
ILE A 256
LEU A 286
ALA A 139
None
0.74A 3r9sC-1l8wA:
undetectable
3r9sC-1l8wA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lf9 GLUCOAMYLASE

(Thermoanaerobacterium
thermosaccharolyticum)
PF00723
(Glyco_hydro_15)
PF09137
(Glucodextran_N)
4 ALA A 422
ILE A 426
LEU A 455
ALA A 462
None
0.90A 3r9sC-1lf9A:
undetectable
3r9sC-1lf9A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lss TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKA
HOMOLOG


(Methanocaldococcus
jannaschii)
PF02254
(TrkA_N)
4 ALA A  16
ILE A  26
LEU A  28
GLU A  21
None
0.90A 3r9sC-1lssA:
undetectable
3r9sC-1lssA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o5o URACIL
PHOSPHORIBOSYLTRANSF
ERASE


(Thermotoga
maritima)
PF14681
(UPRTase)
4 ALA A 143
ILE A  77
LEU A 129
GLU A 113
None
0.90A 3r9sC-1o5oA:
undetectable
3r9sC-1o5oA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oy0 KETOPANTOATE
HYDROXYMETHYLTRANSFE
RASE


(Mycobacterium
tuberculosis)
PF02548
(Pantoate_transf)
4 ALA A 185
ILE A 209
LEU A 213
ALA A 154
None
0.87A 3r9sC-1oy0A:
undetectable
3r9sC-1oy0A:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vpb PUTATIVE MODULATOR
OF DNA GYRASE


(Bacteroides
thetaiotaomicron)
PF01523
(PmbA_TldD)
4 ALA A 140
ILE A 147
LEU A 218
ALA A 182
None
0.76A 3r9sC-1vpbA:
undetectable
3r9sC-1vpbA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wn0 HISTIDINE-CONTAINING
PHOSPHOTRANSFER
PROTEIN


(Zea mays)
PF01627
(Hpt)
4 ALA A  54
ILE A  58
LEU A  82
ALA A  91
None
0.83A 3r9sC-1wn0A:
undetectable
3r9sC-1wn0A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2db5 INAD-LIKE PROTEIN

(Homo sapiens)
PF00595
(PDZ)
4 ALA A  96
ILE A  82
LEU A  87
ALA A  45
None
0.82A 3r9sC-2db5A:
undetectable
3r9sC-2db5A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dgj HYPOTHETICAL PROTEIN
EBHA


(Staphylococcus
aureus)
PF01468
(GA)
4 ALA A 122
ILE A  94
LEU A 102
ALA A  84
None
0.82A 3r9sC-2dgjA:
undetectable
3r9sC-2dgjA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e0w GAMMA-GLUTAMYLTRANSP
EPTIDASE


(Escherichia
coli)
PF01019
(G_glu_transpept)
4 ALA A 329
ILE A 325
LEU A 307
ALA A 360
None
0.82A 3r9sC-2e0wA:
undetectable
3r9sC-2e0wA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2giy GLYCOPROTEIN E

(Human
alphaherpesvirus
1)
PF02480
(Herpes_gE)
4 ALA A 384
ILE A 276
LEU A 356
ALA A 231
None
0.67A 3r9sC-2giyA:
undetectable
3r9sC-2giyA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gj7 GLYCOPROTEIN E

(Human
alphaherpesvirus
1)
no annotation 4 ALA F 384
ILE F 276
LEU F 356
ALA F 231
None
0.66A 3r9sC-2gj7F:
undetectable
3r9sC-2gj7F:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hoe N-ACETYLGLUCOSAMINE
KINASE


(Thermotoga
maritima)
PF00480
(ROK)
4 ILE A 122
LEU A  78
GLU A  81
ALA A 353
None
0.87A 3r9sC-2hoeA:
undetectable
3r9sC-2hoeA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hxg L-ARABINOSE
ISOMERASE


(Escherichia
coli)
PF02610
(Arabinose_Isome)
PF11762
(Arabinose_Iso_C)
4 ALA A 313
ILE A 317
LEU A 176
ALA A 198
None
0.88A 3r9sC-2hxgA:
3.5
3r9sC-2hxgA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2id0 EXORIBONUCLEASE 2

(Escherichia
coli)
PF00575
(S1)
PF00773
(RNB)
PF08206
(OB_RNB)
4 ALA A  62
ILE A  60
LEU A  36
GLU A  74
None
0.81A 3r9sC-2id0A:
undetectable
3r9sC-2id0A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j5g ALR4455 PROTEIN

(Nostoc sp. PCC
7120)
PF00378
(ECH_1)
4 ALA D 202
ILE D 111
LEU D 132
GLU D  26
None
0.89A 3r9sC-2j5gD:
23.3
3r9sC-2j5gD:
25.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jgr YEGS

(Escherichia
coli)
PF00781
(DAGK_cat)
4 ALA A  63
ILE A  70
LEU A  88
ALA A 116
None
0.90A 3r9sC-2jgrA:
undetectable
3r9sC-2jgrA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2obn HYPOTHETICAL PROTEIN

(Trichormus
variabilis)
PF07755
(DUF1611)
PF17396
(DUF1611_N)
4 ILE A  40
LEU A  76
GLU A  66
ALA A 101
None
0.83A 3r9sC-2obnA:
undetectable
3r9sC-2obnA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p1r LIPID KINASE YEGS

(Salmonella
enterica)
PF00781
(DAGK_cat)
4 ALA A  63
ILE A  70
LEU A  88
ALA A 116
None
NA  A 300 (-4.9A)
None
None
0.86A 3r9sC-2p1rA:
undetectable
3r9sC-2p1rA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q5o PHENYLPYRUVATE
DECARBOXYLASE


(Azospirillum
brasilense)
PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
4 ALA A 141
ILE A 145
LEU A 135
ALA A 170
None
0.62A 3r9sC-2q5oA:
undetectable
3r9sC-2q5oA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vd9 ALANINE RACEMASE

(Bacillus
anthracis)
PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N)
4 ALA A  53
ILE A  80
LEU A  64
ALA A  44
MLY  A  54 ( 3.0A)
None
None
None
0.85A 3r9sC-2vd9A:
undetectable
3r9sC-2vd9A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wjg FERROUS IRON
TRANSPORT PROTEIN B
HOMOLOG


(Methanocaldococcus
jannaschii)
PF02421
(FeoB_N)
4 ALA A 114
ILE A  19
LEU A 144
ALA A 158
None
0.68A 3r9sC-2wjgA:
undetectable
3r9sC-2wjgA:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wji FERROUS IRON
TRANSPORT PROTEIN B
HOMOLOG


(Methanocaldococcus
jannaschii)
PF02421
(FeoB_N)
4 ALA A 114
ILE A  19
LEU A 144
ALA A 158
None
0.69A 3r9sC-2wjiA:
undetectable
3r9sC-2wjiA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x58 PEROXISOMAL
BIFUNCTIONAL ENZYME


(Rattus
norvegicus)
PF00378
(ECH_1)
PF00725
(3HCDH)
PF02737
(3HCDH_N)
4 ALA A  61
GLU A 103
GLU A 123
ALA A 132
GOL  A 770 (-4.1A)
GOL  A 770 (-2.9A)
GOL  A 770 ( 3.5A)
GOL  A 770 (-3.8A)
0.32A 3r9sC-2x58A:
19.9
3r9sC-2x58A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xrm INTRACELLULAR
SUBTILISIN PROTEASE


(Bacillus
clausii)
PF00082
(Peptidase_S8)
4 ALA A 259
ILE A 263
LEU A 305
ALA A 229
None
0.87A 3r9sC-2xrmA:
4.1
3r9sC-2xrmA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bf0 PROTEASE 4

(Escherichia
coli)
PF01343
(Peptidase_S49)
4 ALA A 333
ILE A 385
LEU A 370
ALA A 407
None
0.89A 3r9sC-3bf0A:
11.9
3r9sC-3bf0A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bw2 2-NITROPROPANE
DIOXYGENASE


(Streptomyces
ansochromogenes)
PF03060
(NMO)
4 ALA A 213
ILE A 217
LEU A 196
ALA A 229
None
0.82A 3r9sC-3bw2A:
undetectable
3r9sC-3bw2A:
26.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ce6 ADENOSYLHOMOCYSTEINA
SE


(Mycobacterium
tuberculosis)
PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase)
4 ALA A 160
ILE A 153
LEU A 141
ALA A  91
None
0.81A 3r9sC-3ce6A:
undetectable
3r9sC-3ce6A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cgg SAM-DEPENDENT
METHYLTRANSFERASE


(Corynebacterium
glutamicum)
PF13649
(Methyltransf_25)
4 ALA A 142
ILE A 132
LEU A 166
ALA A 189
None
NHE  A 195 ( 4.9A)
None
None
0.86A 3r9sC-3cggA:
undetectable
3r9sC-3cggA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3b 30S RIBOSOMAL
PROTEIN S10


(Escherichia
coli)
PF00338
(Ribosomal_S10)
4 ALA J  21
ILE J  25
LEU J  71
ALA J  12
None
0.82A 3r9sC-3d3bJ:
undetectable
3r9sC-3d3bJ:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3del ARGININE BINDING
PROTEIN


(Chlamydia
trachomatis)
PF00497
(SBP_bac_3)
4 ALA B  64
ILE B  61
LEU B  75
ALA B  96
None
0.77A 3r9sC-3delB:
undetectable
3r9sC-3delB:
25.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e13 PUTATIVE IRON-UPTAKE
ABC TRANSPORT
SYSTEM,PERIPLASMIC
IRON-BINDING PROTEIN


(Campylobacter
jejuni)
PF13343
(SBP_bac_6)
4 ALA X 163
ILE X 314
LEU X 151
ALA X 156
None
0.85A 3r9sC-3e13X:
undetectable
3r9sC-3e13X:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fhh OUTER MEMBRANE HEME
RECEPTOR SHUA


(Shigella
dysenteriae)
PF00593
(TonB_dep_Rec)
PF07715
(Plug)
4 ALA A 170
ILE A 168
LEU A 197
ALA A  95
None
0.75A 3r9sC-3fhhA:
undetectable
3r9sC-3fhhA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h4m PROTEASOME-ACTIVATIN
G NUCLEOTIDASE


(Methanocaldococcus
jannaschii)
PF00004
(AAA)
4 ALA A 276
ILE A 272
LEU A 322
ALA A 325
None
0.84A 3r9sC-3h4mA:
undetectable
3r9sC-3h4mA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hko CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 2
CALMODULIN-LIKE EF
HANDS


(Cryptosporidium
parvum)
PF00069
(Pkinase)
4 ALA A 310
ILE A 316
LEU A 292
ALA A 244
None
0.90A 3r9sC-3hkoA:
undetectable
3r9sC-3hkoA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3icj UNCHARACTERIZED
METAL-DEPENDENT
HYDROLASE


(Pyrococcus
furiosus)
PF07969
(Amidohydro_3)
4 ALA A 265
ILE A 290
LEU A 267
ALA A 246
None
0.76A 3r9sC-3icjA:
2.9
3r9sC-3icjA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iuk UNCHARACTERIZED
PROTEIN


(Paenarthrobacter
aurescens)
PF05960
(DUF885)
4 ALA A 160
ILE A 165
LEU A 104
ALA A 153
None
0.84A 3r9sC-3iukA:
undetectable
3r9sC-3iukA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kds CELL DIVISION
PROTEIN FTSH


(Thermotoga
maritima)
PF00004
(AAA)
PF01434
(Peptidase_M41)
4 ALA E 428
ILE E 582
LEU E 597
GLU E 424
None
None
None
NHX  E 998 (-3.0A)
0.89A 3r9sC-3kdsE:
undetectable
3r9sC-3kdsE:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3keh GLUCOCEREBROSIDASE

(Homo sapiens)
PF02055
(Glyco_hydro_30)
PF17189
(Glyco_hydro_30C)
4 ALA A 232
ILE A 260
LEU A 278
ALA A 309
None
0.67A 3r9sC-3kehA:
undetectable
3r9sC-3kehA:
19.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3kqf ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN


(Bacillus
anthracis)
PF00378
(ECH_1)
4 ALA A  68
GLU A 116
GLU A 136
ALA A 145
None
0.37A 3r9sC-3kqfA:
27.5
3r9sC-3kqfA:
34.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE


(Listeria
monocytogenes)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
PF16582
(TPP_enzyme_M_2)
4 ALA A 429
ILE A 411
LEU A 256
GLU A  93
None
0.81A 3r9sC-3lq1A:
undetectable
3r9sC-3lq1A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m2t PROBABLE
DEHYDROGENASE


(Chromobacterium
violaceum)
PF01408
(GFO_IDH_MocA)
4 ALA A 185
ILE A 150
LEU A 152
ALA A 211
None
0.83A 3r9sC-3m2tA:
undetectable
3r9sC-3m2tA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n26 AMINO ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING PROTEIN


(Chlamydia
pneumoniae)
PF00497
(SBP_bac_3)
4 ALA A  61
ILE A  58
LEU A  72
ALA A  93
None
0.86A 3r9sC-3n26A:
undetectable
3r9sC-3n26A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pi7 NADH OXIDOREDUCTASE

(Mesorhizobium
loti)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 ALA A  82
ILE A  68
LEU A  15
ALA A  12
GOL  A 349 (-4.7A)
None
None
None
0.66A 3r9sC-3pi7A:
undetectable
3r9sC-3pi7A:
25.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE


(Pseudomonas
aeruginosa)
PF00132
(Hexapep)
PF04613
(LpxD)
4 ALA A 262
ILE A 264
LEU A 276
ALA A 241
None
0.88A 3r9sC-3pmoA:
undetectable
3r9sC-3pmoA:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q2k OXIDOREDUCTASE

(Bordetella
pertussis)
PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C)
4 ALA A 225
ILE A 237
LEU A 227
ALA A 334
None
0.79A 3r9sC-3q2kA:
undetectable
3r9sC-3q2kA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qax PROBABLE ABC
TRANSPORTER
ARGININE-BINDING
PROTEIN ARTJ


(Chlamydia
pneumoniae)
PF00497
(SBP_bac_3)
4 ALA A  40
ILE A  37
LEU A  51
ALA A  72
None
0.84A 3r9sC-3qaxA:
undetectable
3r9sC-3qaxA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qjp PUTATIVE
UNCHARACTERIZED
PROTEIN PH0350


(Pyrococcus
horikoshii)
PF01881
(Cas_Cas6)
4 ALA A  40
LEU A  29
GLU A  36
ALA A  93
None
0.87A 3r9sC-3qjpA:
undetectable
3r9sC-3qjpA:
20.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3qxi ENOYL-COA HYDRATASE
ECHA1


(Mycobacterium
marinum)
PF00378
(ECH_1)
4 ALA A 103
ILE A  59
LEU A 189
ALA A 183
None
0.90A 3r9sC-3qxiA:
28.7
3r9sC-3qxiA:
48.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3r0o CARNITINYL-COA
DEHYDRATASE


(Mycobacterium
avium)
PF00378
(ECH_1)
5 ALA A  73
ILE A  78
LEU A  84
GLU A 120
ALA A 149
None
0.63A 3r9sC-3r0oA:
43.1
3r9sC-3r0oA:
75.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3r0o CARNITINYL-COA
DEHYDRATASE


(Mycobacterium
avium)
PF00378
(ECH_1)
5 ALA A  73
LEU A  84
GLU A 120
GLU A 140
ALA A 149
None
0.55A 3r9sC-3r0oA:
43.1
3r9sC-3r0oA:
75.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3r9s CARNITINYL-COA
DEHYDRATASE


(Mycobacterium
avium)
PF00378
(ECH_1)
6 ALA A  67
ILE A  72
LEU A  78
GLU A 114
GLU A 134
ALA A 143
BEZ  A 264 ( 3.7A)
None
None
BEZ  A 264 (-2.6A)
BEZ  A 264 (-3.3A)
BEZ  A 264 (-3.5A)
0.23A 3r9sC-3r9sA:
45.8
3r9sC-3r9sA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3r9s CARNITINYL-COA
DEHYDRATASE


(Mycobacterium
avium)
PF00378
(ECH_1)
5 ALA A  67
ILE A  72
LEU A  78
GLU A 134
ALA A 142
BEZ  A 264 ( 3.7A)
None
None
BEZ  A 264 (-3.3A)
BEZ  A 264 (-4.2A)
1.39A 3r9sC-3r9sA:
45.8
3r9sC-3r9sA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s2s PUTATIVE
PYRAZINAMIDASE/NICOT
INAMIDASE


(Streptococcus
mutans)
PF00857
(Isochorismatase)
4 ALA A 141
ILE A 151
LEU A 128
ALA A 169
None
0.88A 3r9sC-3s2sA:
undetectable
3r9sC-3s2sA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tm9 BACTERIAL HEMOGLOBIN

(Vitreoscilla
stercoraria)
PF00042
(Globin)
4 ALA A  64
ILE A 129
LEU A  71
ALA A  77
HEM  A 201 ( 4.9A)
HEM  A 201 ( 4.6A)
None
None
0.78A 3r9sC-3tm9A:
undetectable
3r9sC-3tm9A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ttl POLYAMINE TRANSPORT
PROTEIN


(Pseudomonas
aeruginosa)
PF13416
(SBP_bac_8)
4 ALA A 268
ILE A 263
LEU A 340
GLU A 181
None
0.89A 3r9sC-3ttlA:
undetectable
3r9sC-3ttlA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dll 2-HYDROXY-3-OXOPROPI
ONATE REDUCTASE


(Polaromonas sp.
JS666)
PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11)
4 ALA A 239
ILE A 234
LEU A 244
ALA A 212
None
0.89A 3r9sC-4dllA:
undetectable
3r9sC-4dllA:
25.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE


([Clostridium]
papyrosolvens)
PF02055
(Glyco_hydro_30)
PF17189
(Glyco_hydro_30C)
4 ALA A 284
ILE A 280
LEU A  41
ALA A  21
None
0.81A 3r9sC-4fmvA:
undetectable
3r9sC-4fmvA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g09 HISTIDINOL
DEHYDROGENASE


(Brucella suis)
PF00815
(Histidinol_dh)
4 ALA A 146
ILE A 157
LEU A 129
ALA A 175
None
0.89A 3r9sC-4g09A:
undetectable
3r9sC-4g09A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g9k ROTENONE-INSENSITIVE
NADH-UBIQUINONE
OXIDOREDUCTASE


(Saccharomyces
cerevisiae)
PF07992
(Pyr_redox_2)
4 ALA A 165
ILE A  46
LEU A 159
ALA A 127
ALA  A 165 ( 0.0A)
ILE  A  46 ( 0.4A)
LEU  A 159 ( 0.6A)
ALA  A 127 ( 0.0A)
0.85A 3r9sC-4g9kA:
undetectable
3r9sC-4g9kA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h5y LIDA PROTEIN,
SUBSTRATE OF THE
DOT/ICM SYSTEM


(Legionella
pneumophila)
no annotation 4 ALA A 212
ILE A 216
LEU A 152
ALA A 145
None
0.86A 3r9sC-4h5yA:
undetectable
3r9sC-4h5yA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jqf CST COMPLEX SUBUNIT
STN1


(Homo sapiens)
PF09170
(STN1_2)
4 ALA A 239
ILE A 244
LEU A 204
ALA A 270
None
0.90A 3r9sC-4jqfA:
undetectable
3r9sC-4jqfA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kh9 HYPOTHETICAL PROTEIN

(Legionella
pneumophila)
PF16024
(DUF4785)
4 ALA A 199
ILE A 201
LEU A 258
ALA A 243
None
0.90A 3r9sC-4kh9A:
undetectable
3r9sC-4kh9A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lls GERANYLTRANSTRANSFER
ASE


(Roseobacter
denitrificans)
PF00348
(polyprenyl_synt)
4 ALA A  66
ILE A  63
LEU A  49
ALA A 189
None
0.81A 3r9sC-4llsA:
undetectable
3r9sC-4llsA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n01 PERIPLASMIC BINDING
PROTEIN


(Veillonella
parvula)
PF01497
(Peripla_BP_2)
4 ALA A 325
ILE A 196
LEU A 200
ALA A 235
None
0.87A 3r9sC-4n01A:
undetectable
3r9sC-4n01A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n03 ABC-TYPE
BRANCHED-CHAIN AMINO
ACID TRANSPORT
SYSTEMS PERIPLASMIC
COMPONENT-LIKE
PROTEIN


(Thermomonospora
curvata)
PF13458
(Peripla_BP_6)
4 ALA A 260
ILE A 244
LEU A 256
ALA A 288
None
0.88A 3r9sC-4n03A:
undetectable
3r9sC-4n03A:
26.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r3z ARGININE--TRNA
LIGASE, CYTOPLASMIC


(Homo sapiens)
PF00750
(tRNA-synt_1d)
PF03485
(Arg_tRNA_synt_N)
PF05746
(DALR_1)
4 ALA B 640
ILE B 578
LEU B 178
ALA B 559
None
0.76A 3r9sC-4r3zB:
undetectable
3r9sC-4r3zB:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r6g LEUCINE RICH REPEATS
DLRR_K


(synthetic
construct)
PF12799
(LRR_4)
PF13516
(LRR_6)
PF13855
(LRR_8)
4 ALA A 410
ILE A 442
LEU A 434
GLU A 408
None
0.87A 3r9sC-4r6gA:
undetectable
3r9sC-4r6gA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r85 CYTOSINE DEAMINASE

(Klebsiella
pneumoniae)
PF07969
(Amidohydro_3)
4 ALA A  99
ILE A 103
LEU A  59
ALA A 130
None
0.80A 3r9sC-4r85A:
2.2
3r9sC-4r85A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE


(Streptococcus
agalactiae)
PF01048
(PNP_UDP_1)
4 ALA A 199
ILE A 224
GLU A 201
ALA A 128
None
0.90A 3r9sC-4tymA:
undetectable
3r9sC-4tymA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v3q YIII_M4_AII

(synthetic
construct)
PF00514
(Arm)
PF16186
(Arm_3)
4 ALA A  48
ILE A  38
LEU A  13
GLU A  44
None
None
None
CA  A1258 (-3.0A)
0.77A 3r9sC-4v3qA:
undetectable
3r9sC-4v3qA:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w5z CHITINASE 60

(Moritella
marina)
PF00704
(Glyco_hydro_18)
4 ALA A 251
ILE A 255
LEU A 305
ALA A 294
None
0.88A 3r9sC-4w5zA:
undetectable
3r9sC-4w5zA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wzz PUTATIVE SUGAR ABC
TRANSPORTER,
SUBSTRATE-BINDING
PROTEIN


(Lachnoclostridium
phytofermentans)
PF13407
(Peripla_BP_4)
4 ALA A 112
ILE A  55
LEU A 138
ALA A 305
None
0.83A 3r9sC-4wzzA:
4.3
3r9sC-4wzzA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x3m RNA 2'-O RIBOSE
METHYLTRANSFERASE


(Thermus
thermophilus)
PF00588
(SpoU_methylase)
4 ALA A 243
ILE A 126
LEU A 112
ALA A 186
None
None
None
ADN  A 301 ( 4.1A)
0.84A 3r9sC-4x3mA:
undetectable
3r9sC-4x3mA:
26.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zk6 QUINOLINATE SYNTHASE
A


(Pyrococcus
horikoshii)
PF02445
(NadA)
4 ALA A 116
ILE A  94
LEU A 108
ALA A 288
None
0.86A 3r9sC-4zk6A:
undetectable
3r9sC-4zk6A:
25.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zn0 THIOREDOXIN
REDUCTASE


(Methanosarcina
mazei)
PF07992
(Pyr_redox_2)
4 ALA A 300
ILE A 107
LEU A   7
GLU A 266
None
0.88A 3r9sC-4zn0A:
undetectable
3r9sC-4zn0A:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ahr DNA CROSS-LINK
REPAIR 1A PROTEIN


(Homo sapiens)
PF07522
(DRMBL)
PF12706
(Lactamase_B_2)
4 ALA A 862
ILE A 890
LEU A 894
ALA A 872
None
0.88A 3r9sC-5ahrA:
undetectable
3r9sC-5ahrA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b47 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT


(Sulfurisphaera
tokodaii)
PF01558
(POR)
PF01855
(POR_N)
PF17147
(PFOR_II)
4 ALA A 240
ILE A 266
LEU A 244
ALA A 388
None
0.88A 3r9sC-5b47A:
undetectable
3r9sC-5b47A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c33 RYANODINE RECEPTOR 2

(Mus musculus)
PF00622
(SPRY)
4 ALA A 825
ILE A 659
LEU A 661
ALA A 820
None
0.88A 3r9sC-5c33A:
undetectable
3r9sC-5c33A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ege ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 6


(Mus musculus)
PF01663
(Phosphodiest)
4 ALA A 173
ILE A 187
LEU A  27
ALA A 182
None
0.86A 3r9sC-5egeA:
undetectable
3r9sC-5egeA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5elp NRPS/PKS PROTEIN

(Bacillus
amyloliquefaciens)
no annotation 4 ALA C 234
ILE C 232
GLU C 328
ALA C 316
None
0.90A 3r9sC-5elpC:
undetectable
3r9sC-5elpC:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5izd D-GLYCERALDEHYDE
DEHYDROGENASE
(NADP(+))


(Thermoplasma
acidophilum)
PF00171
(Aldedh)
4 ALA A 424
ILE A 420
LEU A 413
ALA A 402
None
0.86A 3r9sC-5izdA:
undetectable
3r9sC-5izdA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5joz NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43B


(Bacteroides
ovatus)
PF04616
(Glyco_hydro_43)
4 ALA A 394
ILE A 503
LEU A 392
GLU A 472
None
0.85A 3r9sC-5jozA:
undetectable
3r9sC-5jozA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lsr CCMP

(Synechococcus
elongatus)
no annotation 4 ALA A 155
ILE A 166
LEU A 178
ALA A 171
None
0.90A 3r9sC-5lsrA:
undetectable
3r9sC-5lsrA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tky PUTATIVE
UNCHARACTERIZED
PROTEIN


(Chaetomium
thermophilum)
PF00012
(HSP70)
4 ALA A 582
ILE A 551
LEU A 547
ALA A 602
None
0.81A 3r9sC-5tkyA:
undetectable
3r9sC-5tkyA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vog PUTATIVE
PHOSPHORIBOSYLTRANSF
ERASE


(Neisseria
gonorrhoeae)
PF00156
(Pribosyltran)
4 ALA A 124
ILE A  23
LEU A  94
ALA A  44
None
0.90A 3r9sC-5vogA:
undetectable
3r9sC-5vogA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vye L-THREONINE ALDOLASE

(Pseudomonas
putida)
no annotation 4 ALA A 110
ILE A  83
LEU A 117
GLU A 124
None
0.67A 3r9sC-5vyeA:
undetectable
3r9sC-5vyeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wlh LBACAS13A H328A
(C2C2)


(Lachnospiraceae
bacterium
NK4A179)
no annotation 4 ALA A 936
ILE A 943
GLU A 487
ALA A  22
None
None
A  B  -6 ( 3.4A)
A  B  -5 ( 4.8A)
0.88A 3r9sC-5wlhA:
undetectable
3r9sC-5wlhA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xge UNCHARACTERIZED
PROTEIN PA0861


(Pseudomonas
aeruginosa)
no annotation 4 ALA A 285
ILE A 267
LEU A 293
GLU A 275
None
0.85A 3r9sC-5xgeA:
undetectable
3r9sC-5xgeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c0e ISOCITRATE
DEHYDROGENASE


(Legionella
pneumophila)
no annotation 4 ALA A  76
ILE A  38
LEU A 109
ALA A 123
None
0.82A 3r9sC-6c0eA:
undetectable
3r9sC-6c0eA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f9m SERINE PROTEASE

(Planococcus
plakortidis)
no annotation 4 ALA A 260
ILE A 264
LEU A 306
ALA A 230
None
0.83A 3r9sC-6f9mA:
2.5
3r9sC-6f9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fhs ARP5

(Chaetomium
thermophilum)
no annotation 4 ALA J 223
ILE J 216
LEU J 192
GLU J 761
None
0.82A 3r9sC-6fhsJ:
undetectable
3r9sC-6fhsJ:
undetectable