SIMILAR PATTERNS OF AMINO ACIDS FOR 3R9C_A_ECLA451_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bbt | FOOT-AND-MOUTHDISEASE VIRUS(SUBUNIT VP1) (Foot-and-mouthdisease virus) |
PF00073(Rhv) | 5 | ALA 1 121LEU 1 126LEU 1 53ALA 1 183VAL 1 62 | None | 1.19A | 3r9cA-1bbt1:undetectable | 3r9cA-1bbt1:19.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bh6 | SUBTILISIN DY (Bacilluslicheniformis) |
PF00082(Peptidase_S8) | 5 | ALA A 176LEU A 250ALA A 231VAL A 84THR A 71 | NA A 502 ( 4.1A)NoneNoneNoneNone | 1.26A | 3r9cA-1bh6A:undetectable | 3r9cA-1bh6A:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c3l | SUBTILISIN-CARLSBERG (Bacilluslicheniformis) |
PF00082(Peptidase_S8) | 5 | ALA A 176LEU A 250ALA A 231VAL A 84THR A 71 | CA A 284 ( 4.3A)NoneNoneNoneNone | 1.20A | 3r9cA-1c3lA:undetectable | 3r9cA-1c3lA:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dj0 | PSEUDOURIDINESYNTHASE I (Escherichiacoli) |
PF01416(PseudoU_synth_1) | 5 | ALA A 237LEU A 227ILE A 224ALA A 152VAL A 178 | None | 0.87A | 3r9cA-1dj0A:0.0 | 3r9cA-1dj0A:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ekq | HYDROXYETHYLTHIAZOLEKINASE (Bacillussubtilis) |
PF02110(HK) | 5 | ALA A 80LEU A 117ILE A 111ALA A 108THR A 130 | None | 1.23A | 3r9cA-1ekqA:undetectable | 3r9cA-1ekqA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gll | GLYCEROL KINASE (Escherichiacoli) |
no annotation | 5 | ALA Y 412LEU Y 418ALA Y 379THR Y 339VAL Y 336 | ACP Y 601 (-3.9A)NoneNoneNoneNone | 1.21A | 3r9cA-1gllY:undetectable | 3r9cA-1gllY:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gvh | FLAVOHEMOPROTEIN (Escherichiacoli) |
PF00042(Globin)PF00175(NAD_binding_1)PF00970(FAD_binding_6) | 5 | LEU A 189LEU A 172ILE A 219ALA A 220VAL A 239 | None | 1.45A | 3r9cA-1gvhA:0.0 | 3r9cA-1gvhA:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gz7 | LIPASE 2 (Diutina rugosa) |
PF00135(COesterase) | 5 | ALA A 470ILE A 238ALA A 237THR A 215VAL A 152 | None | 1.18A | 3r9cA-1gz7A:undetectable | 3r9cA-1gz7A:23.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j9l | STATIONARY PHASESURVIVAL PROTEIN (Thermotogamaritima) |
PF01975(SurE) | 5 | LEU A 19ILE A 126ALA A 125THR A 109VAL A 31 | NoneNoneNoneVO4 A 401 (-3.4A)None | 1.43A | 3r9cA-1j9lA:undetectable | 3r9cA-1j9lA:17.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o8c | YHDH (Escherichiacoli) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ALA A 127LEU A 39ILE A 310ALA A 307THR A 48 | NDP A1325 ( 4.0A)NoneNDP A1325 (-4.3A)NoneNone | 1.43A | 3r9cA-1o8cA:undetectable | 3r9cA-1o8cA:24.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s1d | APYRASE (Homo sapiens) |
PF06079(Apyrase) | 5 | ALA A 306LEU A 64ILE A 37ALA A 38VAL A 102 | None | 1.34A | 3r9cA-1s1dA:undetectable | 3r9cA-1s1dA:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1scj | SUBTILISIN E (Bacillussubtilis) |
PF00082(Peptidase_S8) | 5 | ALA A 176LEU A 250ALA A 231VAL A 84THR A 71 | CA A 382 (-3.8A)NoneNoneNoneNone | 1.31A | 3r9cA-1scjA:undetectable | 3r9cA-1scjA:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sv6 | 2-KETO-4-PENTENOATEHYDRATASE (Escherichiacoli) |
PF01557(FAA_hydrolase) | 5 | ALA A 109LEU A 205LEU A 112ILE A 130ALA A 129 | None | 1.19A | 3r9cA-1sv6A:undetectable | 3r9cA-1sv6A:22.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vhn | PUTATIVE FLAVINOXIDOREDUCTASE (Thermotogamaritima) |
PF01207(Dus) | 5 | ALA A 106LEU A 89ILE A 117VAL A 154VAL A 157 | None | 1.31A | 3r9cA-1vhnA:undetectable | 3r9cA-1vhnA:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xio | ANABAENA SENSORYRHODOPSIN (Nostoc sp. PCC7120) |
PF01036(Bac_rhodopsin) | 5 | ALA A 91LEU A 87LEU A 105ILE A 146THR A 108 | NoneNoneNoneNonePEE A 309 ( 4.6A) | 1.32A | 3r9cA-1xioA:undetectable | 3r9cA-1xioA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ysy | REPLICASEPOLYPROTEIN 1AB(PP1AB) (ORF1AB) (Severe acuterespiratorysyndrome-relatedcoronavirus) |
PF08716(nsp7) | 5 | LEU A 37LEU A 42ILE A 41ALA A 50VAL A 18 | None | 1.05A | 3r9cA-1ysyA:undetectable | 3r9cA-1ysyA:12.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zbe | COAT PROTEIN VP1 (Foot-and-mouthdisease virus) |
PF00073(Rhv) | 5 | ALA 1 121LEU 1 126LEU 1 53ALA 1 181VAL 1 62 | None | 1.12A | 3r9cA-1zbe1:undetectable | 3r9cA-1zbe1:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a2d | N-ACETYLGALACTOSAMINE KINASE (Homo sapiens) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C)PF10509(GalKase_gal_bdg) | 5 | ALA A 149LEU A 68ILE A 69ALA A 70THR A 160 | None | 0.98A | 3r9cA-2a2dA:undetectable | 3r9cA-2a2dA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a4k | 3-OXOACYL-[ACYLCARRIER PROTEIN]REDUCTASE (Thermusthermophilus) |
PF13561(adh_short_C2) | 5 | LEU A 75LEU A 126THR A 8VAL A 34VAL A 70 | None | 1.27A | 3r9cA-2a4kA:undetectable | 3r9cA-2a4kA:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2axo | HYPOTHETICAL PROTEINATU2684 (Agrobacteriumfabrum) |
PF06764(DUF1223) | 5 | ALA A 249LEU A 108LEU A 120ILE A 119ALA A 118 | None | 1.03A | 3r9cA-2axoA:undetectable | 3r9cA-2axoA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c0n | A197 (Sulfolobusturretedicosahedralvirus 1) |
no annotation | 5 | ALA A 44LEU A 118ILE A 123THR A 162VAL A 152 | NoneNoneNoneNoneDIO A1201 (-4.0A) | 1.30A | 3r9cA-2c0nA:undetectable | 3r9cA-2c0nA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cbf | COBALT-PRECORRIN-4TRANSMETHYLASE (Bacillusmegaterium) |
PF00590(TP_methylase) | 5 | LEU A 173LEU A 155ILE A 180ALA A 181THR A 150 | None | 1.37A | 3r9cA-2cbfA:undetectable | 3r9cA-2cbfA:23.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2det | TRNA-SPECIFIC2-THIOURIDYLASE MNMA (Escherichiacoli) |
PF03054(tRNA_Me_trans) | 5 | LEU A 364ILE A 288ALA A 289VAL A 340VAL A 337 | None | 0.88A | 3r9cA-2detA:undetectable | 3r9cA-2detA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e28 | PYRUVATE KINASE (Geobacillusstearothermophilus) |
PF00224(PK)PF00391(PEP-utilizers)PF02887(PK_C) | 5 | ALA A 339ILE A 303ALA A 302THR A 277VAL A 275 | None | 1.25A | 3r9cA-2e28A:undetectable | 3r9cA-2e28A:24.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eer | NAD-DEPENDENTALCOHOLDEHYDROGENASE (Sulfurisphaeratokodaii) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ALA A 193LEU A 308ILE A 305THR A 153VAL A 318 | None | 1.43A | 3r9cA-2eerA:undetectable | 3r9cA-2eerA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2es9 | PUTATIVE CYTOPLASMICPROTEIN (Salmonellaenterica) |
PF08986(DUF1889) | 5 | ALA A 12LEU A 45ILE A 41ALA A 38VAL A 58 | None | 1.44A | 3r9cA-2es9A:undetectable | 3r9cA-2es9A:13.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fyi | HTH-TYPETRANSCRIPTIONALREGULATOR CBL (Escherichiacoli) |
PF03466(LysR_substrate) | 5 | LEU A 242LEU A 186ILE A 189ALA A 190THR A 196 | None | 0.82A | 3r9cA-2fyiA:undetectable | 3r9cA-2fyiA:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gx8 | NIF3-RELATED PROTEIN (Bacillus cereus) |
PF01784(NIF3) | 5 | LEU A 71LEU A 31ILE A 99ALA A 98VAL A 43 | None | 1.43A | 3r9cA-2gx8A:undetectable | 3r9cA-2gx8A:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hmf | PROBABLEASPARTOKINASE (Methanocaldococcusjannaschii) |
PF00696(AA_kinase)PF01842(ACT)PF13840(ACT_7) | 5 | ALA A 427LEU A 463ILE A 312ALA A 311THR A 245 | None | 1.45A | 3r9cA-2hmfA:2.2 | 3r9cA-2hmfA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jg2 | SERINEPALMITOYLTRANSFERASE (Sphingomonaspaucimobilis) |
PF00155(Aminotran_1_2) | 5 | ALA A 60LEU A 368ILE A 49ALA A 48VAL A 43 | None | 1.35A | 3r9cA-2jg2A:undetectable | 3r9cA-2jg2A:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p4q | 6-PHOSPHOGLUCONATEDEHYDROGENASE,DECARBOXYLATING 1 (Saccharomycescerevisiae) |
PF00393(6PGD)PF03446(NAD_binding_2) | 5 | ALA A 177LEU A 352ILE A 357ALA A 358THR A 376 | None | 1.26A | 3r9cA-2p4qA:undetectable | 3r9cA-2p4qA:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qcm | URIDINE5'-MONOPHOSPHATESYNTHASE (UMPSYNTHASE) (Homo sapiens) |
PF00215(OMPdecase) | 5 | ALA A 258LEU A 280ILE A 309ALA A 337VAL A 239 | None | 1.28A | 3r9cA-2qcmA:undetectable | 3r9cA-2qcmA:23.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wzr | POLYPROTEIN (Foot-and-mouthdisease virus) |
PF00073(Rhv) | 5 | ALA 1 122LEU 1 127LEU 1 54ALA 1 189VAL 1 63 | None | 1.15A | 3r9cA-2wzr1:undetectable | 3r9cA-2wzr1:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x1i | 4-ALPHA-GLUCANOTRANSFERASE (Thermusbrockianus) |
PF02446(Glyco_hydro_77) | 5 | ALA A 283LEU A 289ILE A 337ALA A 339VAL A 388 | None | 1.43A | 3r9cA-2x1iA:undetectable | 3r9cA-2x1iA:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xj9 | MIPZ (Caulobactervibrioides) |
PF09140(MipZ) | 5 | ILE A 234ALA A 235THR A 27VAL A 23THR A 20 | NoneNoneNoneNoneAGS A1272 (-3.7A) | 1.31A | 3r9cA-2xj9A:undetectable | 3r9cA-2xj9A:24.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2xkr | PUTATIVE CYTOCHROMEP450 142 (Mycobacteriumtuberculosis) |
PF00067(p450) | 5 | LEU A 159LEU A 163LEU A 226ILE A 229THR A 234 | NonePG4 A1399 (-4.8A)HEM A1400 (-4.4A)PG4 A1399 ( 4.5A)HEM A1400 (-3.7A) | 0.66A | 3r9cA-2xkrA:42.5 | 3r9cA-2xkrA:31.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2xkr | PUTATIVE CYTOCHROMEP450 142 (Mycobacteriumtuberculosis) |
PF00067(p450) | 5 | LEU A 159LEU A 226ILE A 229THR A 234VAL A 277 | NoneHEM A1400 (-4.4A)PG4 A1399 ( 4.5A)HEM A1400 (-3.7A)HEM A1400 (-4.5A) | 0.67A | 3r9cA-2xkrA:42.5 | 3r9cA-2xkrA:31.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xwu | IMPORTIN13 (Homo sapiens) |
PF03810(IBN_N)PF08389(Xpo1) | 5 | ALA B 312LEU B 336LEU B 323LEU B 282ILE B 283 | None | 1.04A | 3r9cA-2xwuB:undetectable | 3r9cA-2xwuB:20.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2zbz | CYTOCHROME P450-SU1 (Streptomycesgriseolus) |
PF00067(p450) | 5 | LEU A 180LEU A 240ILE A 243ALA A 244THR A 248 | VDX A 501 (-4.2A)HEM A 413 ( 4.5A)VDX A 501 (-4.2A)HEM A 413 (-3.5A)HEM A 413 (-3.2A) | 0.67A | 3r9cA-2zbzA:41.9 | 3r9cA-2zbzA:35.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zci | PHOSPHOENOLPYRUVATECARBOXYKINASE [GTP] (Corynebacteriumglutamicum) |
PF00821(PEPCK_C)PF17297(PEPCK_N) | 5 | ALA A 445LEU A 498ALA A 567THR A 538THR A 431 | None | 1.46A | 3r9cA-2zciA:undetectable | 3r9cA-2zciA:23.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a8k | AMINOMETHYLTRANSFERASE (Escherichiacoli) |
PF01571(GCV_T)PF08669(GCV_T_C) | 5 | ALA A 203LEU A 181ALA A 155VAL A 167VAL A 176 | None | 1.42A | 3r9cA-3a8kA:undetectable | 3r9cA-3a8kA:24.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3afg | SUBTILISIN-LIKESERINE PROTEASE (Thermococcuskodakarensis) |
PF00082(Peptidase_S8)PF04151(PPC) | 5 | ALA A 206LEU A 208ILE A 145VAL A 229VAL A 233 | None | 1.44A | 3r9cA-3afgA:undetectable | 3r9cA-3afgA:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ce6 | ADENOSYLHOMOCYSTEINASE (Mycobacteriumtuberculosis) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | ALA A 83LEU A 49ALA A 426VAL A 242THR A 216 | None | 1.30A | 3r9cA-3ce6A:undetectable | 3r9cA-3ce6A:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cnh | HYDROLASE FAMILYPROTEIN (Deinococcusradiodurans) |
PF13419(HAD_2) | 5 | ALA A 144LEU A 106LEU A 150ALA A 153VAL A 163 | None | 1.02A | 3r9cA-3cnhA:undetectable | 3r9cA-3cnhA:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cq0 | PUTATIVETRANSALDOLASEYGR043C (Saccharomycescerevisiae) |
PF00923(TAL_FSA) | 5 | LEU A 171ALA A 181THR A 232VAL A 234VAL A 218 | None | 1.14A | 3r9cA-3cq0A:undetectable | 3r9cA-3cq0A:22.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ejb | BIOTIN BIOSYNTHESISCYTOCHROME P450-LIKEENZYME (Bacillussubtilis) |
PF00067(p450) | 5 | LEU B 164LEU B 230ILE B 233ALA B 234THR B 238 | NoneHEM B 405 ( 4.6A)NoneHEM B 405 (-3.5A)HEM B 405 (-3.7A) | 0.53A | 3r9cA-3ejbB:46.6 | 3r9cA-3ejbB:34.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ftt | PUTATIVEACETYLTRANSFERASESACOL2570 (Staphylococcusaureus) |
PF00132(Hexapep)PF12464(Mac)PF14602(Hexapep_2) | 5 | LEU A 49ILE A 31ALA A 28THR A 69VAL A 75 | None | 1.41A | 3r9cA-3fttA:undetectable | 3r9cA-3fttA:19.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hhd | FATTY ACID SYNTHASE (Homo sapiens) |
PF00109(ketoacyl-synt)PF00698(Acyl_transf_1)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | ILE A 175ALA A 182THR A 105VAL A 107VAL A 109 | None | 1.26A | 3r9cA-3hhdA:undetectable | 3r9cA-3hhdA:19.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hyv | SULFIDE-QUINONEREDUCTASE (Aquifexaeolicus) |
PF07992(Pyr_redox_2) | 5 | LEU A 32ILE A 15ALA A 16VAL A 102VAL A 5 | None | 1.09A | 3r9cA-3hyvA:undetectable | 3r9cA-3hyvA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3isp | HTH-TYPETRANSCRIPTIONALREGULATORRV1985C/MT2039 (Mycobacteriumtuberculosis) |
PF00126(HTH_1)PF03466(LysR_substrate) | 5 | ALA A 64LEU A 44LEU A 69ALA A 72VAL A 37 | None | 1.07A | 3r9cA-3ispA:undetectable | 3r9cA-3ispA:23.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kao | TAGATOSE1,6-DIPHOSPHATEALDOLASE (Staphylococcusaureus) |
PF01791(DeoC) | 5 | ALA A 90LEU A 68LEU A 87ALA A 57THR A 61 | None | 1.28A | 3r9cA-3kaoA:undetectable | 3r9cA-3kaoA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l3s | ENOYL-COAHYDRATASE/ISOMERASEFAMILY PROTEIN (Ruegeriapomeroyi) |
PF00378(ECH_1) | 5 | ALA A 42LEU A 21LEU A 23ILE A 57ALA A 110 | None | 1.43A | 3r9cA-3l3sA:undetectable | 3r9cA-3l3sA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mve | UPF0255 PROTEINVV1_0328 (Vibriovulnificus) |
PF06500(DUF1100) | 5 | ALA A 291LEU A 409LEU A 414ILE A 222ALA A 223 | None | 1.40A | 3r9cA-3mveA:undetectable | 3r9cA-3mveA:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nwy | URIDYLATE KINASE (Mycobacteriumtuberculosis) |
PF00696(AA_kinase) | 5 | ALA A 184LEU A 35THR A 122VAL A 124VAL A 105 | None | 1.24A | 3r9cA-3nwyA:undetectable | 3r9cA-3nwyA:21.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3r9b | CYTOCHROME P450164A2 (Mycolicibacteriumsmegmatis) |
PF00067(p450) | 5 | ALA A 95ALA A 256THR A 260VAL A 303THR A 403 | NoneHEM A 501 ( 3.5A)HEM A 501 (-3.4A)HEM A 501 (-4.7A)D12 A 509 ( 4.6A) | 1.06A | 3r9cA-3r9bA:62.5 | 3r9cA-3r9bA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3r9b | CYTOCHROME P450164A2 (Mycolicibacteriumsmegmatis) |
PF00067(p450) | 9 | LEU A 180LEU A 184LEU A 252ILE A 255ALA A 256THR A 260VAL A 303VAL A 306THR A 403 | NoneD12 A 509 ( 4.3A)HEM A 501 ( 4.5A)D12 A 509 ( 4.1A)HEM A 501 ( 3.5A)HEM A 501 (-3.4A)HEM A 501 (-4.7A)D12 A 509 ( 4.5A)D12 A 509 ( 4.6A) | 0.52A | 3r9cA-3r9bA:62.5 | 3r9cA-3r9bA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3so4 | METHIONINE-ADENOSYLTRANSFERASE (Entamoebahistolytica) |
PF00438(S-AdoMet_synt_N)PF02772(S-AdoMet_synt_M)PF02773(S-AdoMet_synt_C) | 5 | LEU A 332LEU A 382ALA A 295VAL A 301THR A 321 | None | 1.45A | 3r9cA-3so4A:undetectable | 3r9cA-3so4A:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sqw | ATP-DEPENDENT RNAHELICASE MSS116,MITOCHONDRIAL (Saccharomycescerevisiae) |
PF00270(DEAD)PF00271(Helicase_C) | 5 | ALA A 120LEU A 113ILE A 164ALA A 161THR A 136 | None | 1.36A | 3r9cA-3sqwA:undetectable | 3r9cA-3sqwA:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t58 | SULFHYDRYL OXIDASE 1 (Mus musculus) |
PF00085(Thioredoxin)PF04777(Evr1_Alr) | 5 | ALA A 156LEU A 97LEU A 208ALA A 167VAL A 218 | None | 1.42A | 3r9cA-3t58A:undetectable | 3r9cA-3t58A:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uf6 | LMO1369 PROTEIN (Listeriamonocytogenes) |
PF01515(PTA_PTB) | 5 | ALA A 226LEU A 229ILE A 131ALA A 118VAL A 245 | None | 1.38A | 3r9cA-3uf6A:undetectable | 3r9cA-3uf6A:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vk5 | MOEO5 (Streptomycesviridosporus) |
PF01884(PcrB) | 5 | ALA A 112LEU A 115LEU A 153LEU A 66VAL A 224 | None | 1.34A | 3r9cA-3vk5A:undetectable | 3r9cA-3vk5A:24.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a0w | T-COMPLEX PROTEIN 1SUBUNIT BETA (Bos taurus) |
PF00118(Cpn60_TCP1) | 5 | LEU A 58LEU A 25ILE A 22ALA A 21VAL A 63 | None | 1.23A | 3r9cA-4a0wA:undetectable | 3r9cA-4a0wA:24.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c7o | SIGNAL RECOGNITIONPARTICLE PROTEIN (Escherichiacoli) |
PF00448(SRP54)PF02881(SRP54_N) | 5 | LEU A 240ALA A 106THR A 191VAL A 189VAL A 102 | None | 1.41A | 3r9cA-4c7oA:undetectable | 3r9cA-4c7oA:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ddw | REVERSE GYRASE (Thermotogamaritima) |
PF00270(DEAD)PF01131(Topoisom_bac)PF01751(Toprim) | 5 | LEU A 829ILE A 825ALA A 821VAL A1008VAL A1026 | None | 1.16A | 3r9cA-4ddwA:undetectable | 3r9cA-4ddwA:16.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dhg | MANDELATERACEMASE/MUCONATELACTONIZING PROTEIN (Thermobisporabispora) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ALA A 81LEU A 65ALA A 111VAL A 36VAL A 70 | None | 1.40A | 3r9cA-4dhgA:undetectable | 3r9cA-4dhgA:23.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dn7 | ABC TRANSPORTER,ATP-BINDING PROTEIN (Methanosarcinamazei) |
PF01458(UPF0051) | 5 | ALA A 302LEU A 289ALA A 278VAL A 222THR A 220 | None | 1.09A | 3r9cA-4dn7A:2.4 | 3r9cA-4dn7A:23.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ess | OR187 (syntheticconstruct) |
PF01661(Macro) | 5 | ALA A 152ALA A 115VAL A 89VAL A 128THR A 93 | None | 1.31A | 3r9cA-4essA:undetectable | 3r9cA-4essA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4esw | PYRIMIDINEBIOSYNTHESIS ENZYMETHI13 (Candidaalbicans) |
PF09084(NMT1) | 5 | ALA A 223LEU A 35ILE A 37ALA A 38VAL A 57 | None | 1.42A | 3r9cA-4eswA:undetectable | 3r9cA-4eswA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gh4 | CAPSID PROTEIN VP1 (Foot-and-mouthdisease virus) |
PF00073(Rhv) | 5 | ALA A 121LEU A 126LEU A 53ALA A 182VAL A 62 | None | 1.16A | 3r9cA-4gh4A:undetectable | 3r9cA-4gh4A:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ijn | ACETATE KINASE (Mycolicibacteriumsmegmatis) |
PF00871(Acetate_kinase) | 5 | ALA A 198LEU A 188ILE A 293VAL A 319VAL A 312 | NoneNoneNoneNoneAMP A 402 (-4.1A) | 1.34A | 3r9cA-4ijnA:undetectable | 3r9cA-4ijnA:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l0c | DEFORMYLASE (Pseudomonasputida) |
PF12697(Abhydrolase_6) | 5 | ALA A 104LEU A 114ILE A 202THR A 230VAL A 206 | None | 1.22A | 3r9cA-4l0cA:undetectable | 3r9cA-4l0cA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lgg | PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC (Gallus gallus) |
PF07714(Pkinase_Tyr) | 5 | LEU A 387ILE A 370ALA A 371VAL A 377VAL A 383 | None | 1.42A | 3r9cA-4lggA:undetectable | 3r9cA-4lggA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rit | PYRIDOXAL-DEPENDENTDECARBOXYLASE (Sphaerobacterthermophilus) |
no annotation | 5 | ALA B 278LEU B 363LEU B 136ILE B 133ALA B 132 | None | 1.15A | 3r9cA-4ritB:undetectable | 3r9cA-4ritB:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tl3 | ANABAENA SENSORYRHODOPSIN (Nostoc sp. PCC7120) |
PF01036(Bac_rhodopsin) | 5 | ALA A 91LEU A 87LEU A 105ILE A 146THR A 108 | NoneNoneNoneNonePEE A 319 ( 4.4A) | 1.32A | 3r9cA-4tl3A:undetectable | 3r9cA-4tl3A:21.36 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ubs | PENTALENIC ACIDSYNTHASE (Streptomycesavermitilis) |
PF00067(p450) | 5 | LEU A 178LEU A 237ALA A 241THR A 245THR A 391 | NoneDIF A 502 (-4.4A)HEM A 501 ( 3.8A)HEM A 501 ( 3.3A)None | 1.21A | 3r9cA-4ubsA:42.5 | 3r9cA-4ubsA:32.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ubs | PENTALENIC ACIDSYNTHASE (Streptomycesavermitilis) |
PF00067(p450) | 5 | LEU A 237ILE A 240ALA A 241THR A 245THR A 391 | DIF A 502 (-4.4A)DIF A 502 (-3.3A)HEM A 501 ( 3.8A)HEM A 501 ( 3.3A)None | 1.01A | 3r9cA-4ubsA:42.5 | 3r9cA-4ubsA:32.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4woe | TAUROCYAMINE KINASE (Schistosomamansoni) |
PF00217(ATP-gua_Ptrans)PF02807(ATP-gua_PtransN) | 5 | LEU A 372ILE A 413ALA A 410THR A 408THR A 498 | None | 1.28A | 3r9cA-4woeA:undetectable | 3r9cA-4woeA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xri | PUTATIVEUNCHARACTERIZEDPROTEIN (Chaetomiumthermophilum) |
PF03810(IBN_N)PF13513(HEAT_EZ) | 5 | ALA A 645LEU A 611ILE A 628ALA A 627VAL A 620 | GOL A 915 ( 4.5A)GOL A 911 ( 4.1A)NoneNoneNone | 1.33A | 3r9cA-4xriA:2.8 | 3r9cA-4xriA:19.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z19 | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 3 (Yersinia pestis) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 5 | ALA A 254LEU A 299LEU A 219ALA A 302THR A 116 | NoneNoneNoneSCY A 112 ( 3.7A)None | 1.15A | 3r9cA-4z19A:undetectable | 3r9cA-4z19A:22.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aca | VP1 (Foot-and-mouthdisease virus) |
PF00073(Rhv) | 5 | ALA 1 121LEU 1 126LEU 1 53ALA 1 188VAL 1 62 | None | 1.22A | 3r9cA-5aca1:undetectable | 3r9cA-5aca1:18.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ej2 | CARVEOLDEHYDROGENASE (Mycobacteriumavium) |
PF13561(adh_short_C2) | 5 | ALA A 110ILE A 45ALA A 81VAL A 71THR A 67 | None | 1.36A | 3r9cA-5ej2A:undetectable | 3r9cA-5ej2A:22.02 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gnm | VITAMIN D(3)25-HYDROXYLASE (Pseudonocardiaautotrophica) |
PF00067(p450) | 5 | LEU A 232ILE A 235ALA A 236THR A 240VAL A 283 | HEM A 501 ( 4.7A)NoneHEM A 501 (-3.6A)HEM A 501 (-3.7A)HEM A 501 (-4.7A) | 1.14A | 3r9cA-5gnmA:41.7 | 3r9cA-5gnmA:39.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gsm | EXO-BETA-D-GLUCOSAMINIDASE (Thermococcuskodakarensis) |
PF02449(Glyco_hydro_42) | 5 | ALA A 616LEU A 619ILE A 597VAL A 574VAL A 588 | NoneNonePPI A 809 ( 4.2A)NoneNone | 1.44A | 3r9cA-5gsmA:undetectable | 3r9cA-5gsmA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h45 | DNA REPAIR PROTEINRADA (Thermusthermophilus) |
PF13541(ChlI) | 5 | ALA A 296LEU A 323ALA A 354VAL A 378VAL A 318 | None | 1.27A | 3r9cA-5h45A:undetectable | 3r9cA-5h45A:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i51 | TRANSKETOLASE (Scheffersomycesstipitis) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | ALA A 131LEU A 128ILE A 425ALA A 426VAL A 111 | NoneNoneNonePEG A 707 (-4.5A)None | 1.34A | 3r9cA-5i51A:undetectable | 3r9cA-5i51A:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j0n | INTEGRASE (Escherichiavirus Lambda) |
PF00589(Phage_integrase)PF02899(Phage_int_SAM_1) | 5 | LEU E 229LEU E 216ILE E 271THR E 258THR E 244 | None | 1.26A | 3r9cA-5j0nE:undetectable | 3r9cA-5j0nE:23.04 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5l94 | CYTOCHROME P450 (Bacillusmegaterium) |
PF00067(p450) | 5 | LEU A 238ILE A 241ALA A 242THR A 246VAL A 289 | HEM A 501 (-4.4A)TES A 502 (-4.0A)HEM A 501 (-3.5A)HEM A 501 (-3.4A)TES A 502 (-4.8A) | 0.37A | 3r9cA-5l94A:47.4 | 3r9cA-5l94A:35.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lp5 | RODSHAPE-DETERMININGPROTEIN (MREC) (Helicobacterpylori) |
PF04085(MreC) | 5 | LEU C 128ALA C 156VAL C 159VAL C 195THR C 197 | None | 1.27A | 3r9cA-5lp5C:undetectable | 3r9cA-5lp5C:22.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ojs | TRANSCRIPTION-ASSOCIATED PROTEIN 1 (Saccharomycescerevisiae) |
PF00454(PI3_PI4_kinase)PF02259(FAT) | 5 | LEU T2263LEU T2259ILE T2217ALA T2216VAL T2209 | None | 0.89A | 3r9cA-5ojsT:undetectable | 3r9cA-5ojsT:7.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ol1 | DNA POLYMERASE IIISUBUNIT ALPHA,DNAPOLYMERASE IIISUBUNIT ALPHA (Synechocystissp. PCC 6803) |
no annotation | 5 | LEU A 139LEU A 28ILE A 33ALA A 34VAL A 4 | None | 1.26A | 3r9cA-5ol1A:undetectable | 3r9cA-5ol1A:17.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u2p | SUGAR ABCTRANSPORTERSUBSTRATE-BINDINGPROTEIN (Treponemapallidum) |
PF01547(SBP_bac_1) | 5 | ALA A 221LEU A 217ILE A 384ALA A 383THR A 309 | NoneNoneNoneEDO A 504 (-2.8A)None | 1.40A | 3r9cA-5u2pA:undetectable | 3r9cA-5u2pA:23.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uju | NAD-DEPENDENTALDEHYDEDEHYDROGENASE (Burkholderiamultivorans) |
PF00171(Aldedh) | 5 | ALA A 96LEU A 263ALA A 64VAL A 69THR A 265 | None | 1.42A | 3r9cA-5ujuA:undetectable | 3r9cA-5ujuA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vip | MDCDMDCE (Pseudomonasaeruginosa) |
PF01039(Carboxyl_trans)PF06833(MdcE) | 5 | ALA A 144LEU A 115ILE B 165ALA B 166VAL B 141 | None | 0.98A | 3r9cA-5vipA:undetectable | 3r9cA-5vipA:27.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xn8 | GLYCEROLDEHYDROGENASE (unidentified) |
PF00465(Fe-ADH) | 5 | ALA A 191LEU A 127ALA A 122VAL A 113VAL A 111 | None | 1.10A | 3r9cA-5xn8A:undetectable | 3r9cA-5xn8A:24.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ynl | ARGINASE (Glaciozymaantarctica) |
no annotation | 5 | LEU A 280LEU A 227LEU A 240ILE A 238VAL A 222 | None | 1.15A | 3r9cA-5ynlA:undetectable | 3r9cA-5ynlA:10.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bld | CYTOCHROME P450268A2 CYP268A2 (Mycobacteriummarinum) |
no annotation | 5 | LEU A 187LEU A 256ALA A 260THR A 264VAL A 308 | DXJ A 502 (-3.6A)HEM A 501 ( 4.8A)HEM A 501 ( 3.6A)HEM A 501 (-3.4A)HEM A 501 ( 4.6A) | 0.77A | 3r9cA-6bldA:39.3 | 3r9cA-6bldA:14.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6blm | 4-OXALOCROTONATETAUTOMERASE (Burkholderialata) |
no annotation | 5 | ALA A 94LEU A 24ILE A 69ALA A 71VAL A 39 | None | 1.17A | 3r9cA-6blmA:undetectable | 3r9cA-6blmA:13.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6btm | ALTERNATIVE COMPLEXIII SUBUNIT CALTERNATIVE COMPLEXIII SUBUNIT D (Flavobacteriumjohnsoniae) |
no annotation | 5 | ALA C 214LEU D 16LEU D 144ILE D 145ALA D 8 | None | 1.19A | 3r9cA-6btmC:1.3 | 3r9cA-6btmC:12.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ccz | SERINEHYDROXYMETHYLTRANSFERASE (Medicagotruncatula) |
no annotation | 5 | LEU A 296ALA A 291THR A 314VAL A 312VAL A 309 | NoneLLP A 318 (-3.3A)FMT A 613 ( 4.6A)NoneNone | 1.45A | 3r9cA-6cczA:undetectable | 3r9cA-6cczA:11.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f3m | - (-) |
no annotation | 5 | ALA B 75LEU B 41ALA B 392VAL B 188THR B 162 | None | 1.32A | 3r9cA-6f3mB:undetectable | 3r9cA-6f3mB:undetectable |