SIMILAR PATTERNS OF AMINO ACIDS FOR 3R6W_A_NFZA213

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gan GALECTIN-1

(Rhinella
arenarum) 		PF00337
(Gal-bind_lectin) 		5 PHE A  31
PHE A 107
VAL A  88
PHE A 101
PHE A  80
 None
 1.33A 3r6wA-1ganA:
undetectable
3r6wB-1ganA:
undetectable		 3r6wA-1ganA:
19.02
3r6wB-1ganA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hn0 CHONDROITIN ABC
LYASE I

(Proteus
vulgaris) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF09092
(Lyase_N)
PF09093
(Lyase_catalyt) 		5 PHE A 129
GLY A 156
PHE A 143
VAL A  93
PHE A  31
 None
 1.31A 3r6wA-1hn0A:
0.0
3r6wB-1hn0A:
undetectable		 3r6wA-1hn0A:
13.07
3r6wB-1hn0A:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kz7 GUANINE NUCLEOTIDE
EXCHANGE FACTOR DBS

(Mus musculus) 		PF00169
(PH)
PF00621
(RhoGEF) 		5 PHE A 692
GLU A 644
VAL A 711
TYR A 775
PHE A 715
 None
 1.26A 3r6wA-1kz7A:
0.0
3r6wB-1kz7A:
undetectable		 3r6wA-1kz7A:
22.35
3r6wB-1kz7A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n7r HYALURONIDASE

(Streptococcus
pneumoniae) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		5 GLY A 619
PHE A 594
VAL A 731
PHE A 746
TYR A 795
 None
 1.41A 3r6wA-1n7rA:
0.0
3r6wB-1n7rA:
0.0		 3r6wA-1n7rA:
14.87
3r6wB-1n7rA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nty TRIPLE FUNCTIONAL
DOMAIN PROTEIN

(Homo sapiens) 		PF00169
(PH)
PF00621
(RhoGEF) 		5 PHE A1291
GLU A1245
VAL A1310
TYR A1373
PHE A1314
 None
 1.24A 3r6wA-1ntyA:
0.0
3r6wB-1ntyA:
undetectable		 3r6wA-1ntyA:
19.63
3r6wB-1ntyA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tuh HYPOTHETICAL PROTEIN
EGC068

(uncultured
bacterium) 		PF12680
(SnoaL_2) 		5 PHE A  47
PHE A 138
PHE A  86
TYR A  78
PHE A  35
 None
 1.39A 3r6wA-1tuhA:
undetectable
3r6wB-1tuhA:
undetectable		 3r6wA-1tuhA:
21.66
3r6wB-1tuhA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d3t FATTY OXIDATION
COMPLEX ALPHA
SUBUNIT

(Pseudomonas
fragi) 		PF00378
(ECH_1)
PF00725
(3HCDH)
PF02737
(3HCDH_N) 		5 ASN A  77
PHE A  78
GLY A 148
PHE A 278
PHE A  74
 None
 1.14A 3r6wA-2d3tA:
1.1
3r6wB-2d3tA:
3.2		 3r6wA-2d3tA:
14.81
3r6wB-2d3tA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bn7 FERREDOXIN-LIKE
PROTEIN

(Caulobacter
vibrioides) 		PF07876
(Dabb) 		5 PHE A  64
GLU A  60
PHE A   8
VAL A  83
PHE A  82
 None
ACT  A 102 (-2.9A)
None
None
ACT  A 102 (-4.8A)
 1.15A 3r6wA-3bn7A:
undetectable
3r6wB-3bn7A:
0.0		 3r6wA-3bn7A:
17.67
3r6wB-3bn7A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cm5 CELL DEATH-RELATED
NUCLEASE 4

(Caenorhabditis
elegans) 		PF00929
(RNase_T) 		5 PHE A 108
VAL A  31
PHE A  85
TYR A  89
PHE A  34
 None
 1.27A 3r6wA-3cm5A:
0.0
3r6wB-3cm5A:
0.0		 3r6wA-3cm5A:
21.73
3r6wB-3cm5A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e73 LANC-LIKE PROTEIN 1

(Homo sapiens) 		PF05147
(LANC_like) 		5 PHE A 373
VAL A 116
PHE A 164
TYR A 160
PHE A 106
 None
 1.36A 3r6wA-3e73A:
undetectable
3r6wB-3e73A:
undetectable		 3r6wA-3e73A:
19.56
3r6wB-3e73A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g4e REGUCALCIN

(Homo sapiens) 		PF08450
(SGL) 		5 PHE A 114
GLY A 116
PHE A 178
TYR A 167
PHE A 165
 None
 1.35A 3r6wA-3g4eA:
undetectable
3r6wB-3g4eA:
undetectable		 3r6wA-3g4eA:
22.15
3r6wB-3g4eA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ilr HEPARIN LYASE I

(Bacteroides
thetaiotaomicron) 		PF14099
(Polysacc_lyase) 		5 PHE A 352
GLY A 355
PHE A 238
PHE A 295
PHE A 131
 None
 1.49A 3r6wA-3ilrA:
undetectable
3r6wB-3ilrA:
undetectable		 3r6wA-3ilrA:
19.19
3r6wB-3ilrA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k2q PYROPHOSPHATE-DEPEND
ENT
PHOSPHOFRUCTOKINASE

(Marinobacter
hydrocarbonoclasticus) 		PF00365
(PFK) 		5 PHE A 100
GLY A  42
VAL A 123
TYR A 110
PHE A 108
 None
 1.48A 3r6wA-3k2qA:
4.3
3r6wB-3k2qA:
3.5		 3r6wA-3k2qA:
20.05
3r6wB-3k2qA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n92 ALPHA-AMYLASE, GH57
FAMILY

(Thermococcus
kodakarensis) 		PF03065
(Glyco_hydro_57)
PF09210
(DUF1957) 		5 GLU A 137
VAL A 350
PHE A 259
TYR A 216
PHE A 218
 None
 1.35A 3r6wA-3n92A:
undetectable
3r6wB-3n92A:
undetectable		 3r6wA-3n92A:
18.03
3r6wB-3n92A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caenorhabditis
elegans) 		PF02373
(JmjC) 		5 PHE A 356
GLY A 353
PHE A 582
PHE A 442
PHE A 339
 None
 1.32A 3r6wA-3n9oA:
undetectable
3r6wB-3n9oA:
undetectable		 3r6wA-3n9oA:
18.62
3r6wB-3n9oA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3no8 BTB/POZ
DOMAIN-CONTAINING
PROTEIN 2

(Homo sapiens) 		PF08005
(PHR) 		5 GLY A 405
PHE A 453
VAL A 397
PHE A 499
PHE A 395
 None
 1.49A 3r6wA-3no8A:
undetectable
3r6wB-3no8A:
undetectable		 3r6wA-3no8A:
19.09
3r6wB-3no8A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o53 PROTEIN LRIM1

(Anopheles
gambiae) 		PF00560
(LRR_1)
PF13855
(LRR_8) 		5 ASN A 283
GLY A 229
VAL A 286
PHE A 264
PHE A 257
 None
 1.21A 3r6wA-3o53A:
undetectable
3r6wB-3o53A:
undetectable		 3r6wA-3o53A:
20.57
3r6wB-3o53A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t8u STEROID
DELTA-ISOMERASE

(Comamonas
testosteroni) 		PF12680
(SnoaL_2) 		5 PHE A  82
PHE A  30
VAL A  11
PHE A 101
PHE A  80
 None
 1.48A 3r6wA-3t8uA:
undetectable
3r6wB-3t8uA:
undetectable		 3r6wA-3t8uA:
19.44
3r6wB-3t8uA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vns NRPS ADENYLATION
PROTEIN CYTC1

(Streptomyces
sp.) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		5 PHE A 191
GLY A 216
PHE A 209
PHE A 315
PHE A 318
 None
None
DVA  A 602 ( 4.2A)
DVA  A 602 (-3.7A)
None
 1.39A 3r6wA-3vnsA:
undetectable
3r6wB-3vnsA:
2.1		 3r6wA-3vnsA:
19.19
3r6wB-3vnsA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zs3 THAUMATIN-LIKE
PROTEIN

(Malus domestica) 		PF00314
(Thaumatin) 		5 PHE A   5
GLY A  30
PHE A  31
VAL A  91
PHE A  51
 None
SIN  A1223 (-4.4A)
None
None
None
 1.34A 3r6wA-3zs3A:
undetectable
3r6wB-3zs3A:
undetectable		 3r6wA-3zs3A:
21.60
3r6wB-3zs3A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4byf UNCONVENTIONAL
MYOSIN-IC

(Homo sapiens) 		PF00063
(Myosin_head)
PF00612
(IQ) 		5 ASN A 404
GLY A 105
GLU A 106
VAL A 516
TYR A 613
 None
 1.46A 3r6wA-4byfA:
undetectable
3r6wB-4byfA:
undetectable		 3r6wA-4byfA:
15.56
3r6wB-4byfA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gn8 REGUCALCIN

(Mus musculus) 		PF08450
(SGL) 		5 PHE A 114
GLY A 116
PHE A 178
TYR A 167
PHE A 165
 None
 1.37A 3r6wA-4gn8A:
undetectable
3r6wB-4gn8A:
undetectable		 3r6wA-4gn8A:
23.08
3r6wB-4gn8A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h6j ARYL HYDROCARBON
NUCLEAR TRANSLOCATOR

(Homo sapiens) 		PF14598
(PAS_11) 		5 ASN B 461
GLY B 371
PHE B 412
PHE B 429
PHE B 427
 None
 1.50A 3r6wA-4h6jB:
undetectable
3r6wB-4h6jB:
undetectable		 3r6wA-4h6jB:
21.54
3r6wB-4h6jB:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jra SYNAPTIC VESICLE
GLYCOPROTEIN 2C

(Homo sapiens) 		PF13599
(Pentapeptide_4) 		5 PHE C 547
PHE C 552
VAL C 505
PHE C 502
PHE C 522
 None
 1.49A 3r6wA-4jraC:
undetectable
3r6wB-4jraC:
undetectable		 3r6wA-4jraC:
19.55
3r6wB-4jraC:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m4d LIPOPOLYSACCHARIDE-B
INDING PROTEIN

(Mus musculus) 		PF01273
(LBP_BPI_CETP)
PF02886
(LBP_BPI_CETP_C) 		5 PHE A 424
PHE A 321
PHE A 301
VAL A 383
TYR A 431
 None
 1.27A 3r6wA-4m4dA:
undetectable
3r6wB-4m4dA:
undetectable		 3r6wA-4m4dA:
19.18
3r6wB-4m4dA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mt6 RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 9

(Rattus
norvegicus) 		PF00018
(SH3_1)
PF00169
(PH)
PF00621
(RhoGEF) 		5 PHE A 165
GLU A 122
PHE A 191
TYR A 256
PHE A 198
 None
 1.30A 3r6wA-4mt6A:
undetectable
3r6wB-4mt6A:
undetectable		 3r6wA-4mt6A:
18.74
3r6wB-4mt6A:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n2z GH62
ARABINOFURANOSIDASE

(Podospora
anserina) 		PF03664
(Glyco_hydro_62) 		5 PHE A  78
GLY A 328
PHE A 329
PHE A  89
PHE A  76
 None
 1.20A 3r6wA-4n2zA:
undetectable
3r6wB-4n2zA:
undetectable		 3r6wA-4n2zA:
21.79
3r6wB-4n2zA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n7r GLUTAMYL-TRNA
REDUCTASE 1,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00745
(GlutR_dimer)
PF01488
(Shikimate_DH)
PF05201
(GlutR_N) 		5 GLY A 101
GLU A 148
VAL A 218
PHE A 236
TYR A 150
 None
 1.39A 3r6wA-4n7rA:
undetectable
3r6wB-4n7rA:
3.3		 3r6wA-4n7rA:
18.72
3r6wB-4n7rA:
18.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4n9q FMN-DEPENDENT
NADH-AZOREDUCTASE 1

(Pseudomonas
aeruginosa) 		PF02525
(Flavodoxin_2) 		5 PHE A  60
VAL A 114
PHE A 120
TYR A 131
PHE A 173
 UQ1  A 302 (-4.4A)
None
UQ1  A 302 (-3.9A)
UQ1  A 302 (-3.7A)
UQ1  A 302 (-3.0A)
 0.44A 3r6wA-4n9qA:
35.7
3r6wB-4n9qA:
34.2		 3r6wA-4n9qA:
100.00
3r6wB-4n9qA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r84 SIALYLTRANSFERASE
0160

(Photobacterium
damselae) 		PF11477
(PM0188) 		5 PHE A  90
GLY A  61
GLU A  86
VAL A  34
PHE A  77
 None
 1.38A 3r6wA-4r84A:
4.3
3r6wB-4r84A:
1.9		 3r6wA-4r84A:
17.69
3r6wB-4r84A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tnb G PROTEIN-COUPLED
RECEPTOR KINASE 5

(Homo sapiens) 		PF00069
(Pkinase)
PF00615
(RGS) 		5 GLY A 209
GLU A 514
VAL A 181
TYR A 212
PHE A 186
 None
 1.37A 3r6wA-4tnbA:
undetectable
3r6wB-4tnbA:
undetectable		 3r6wA-4tnbA:
15.57
3r6wB-4tnbA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uac CARBOHYDRATE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT1 FAMILY
(TC 3.A.1.1.-)

([Eubacterium]
rectale) 		PF13416
(SBP_bac_8) 		5 PHE A 413
GLY A 381
PHE A 301
TYR A 217
PHE A 219
 None
None
None
None
PEG  A 502 (-4.3A)
 1.43A 3r6wA-4uacA:
undetectable
3r6wB-4uacA:
undetectable		 3r6wA-4uacA:
20.30
3r6wB-4uacA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5diz PROTEINACEOUS RNASE
P 2

(Arabidopsis
thaliana) 		PF16953
(PRORP)
PF17177
(PPR_long) 		5 PHE A 226
PHE A 495
GLU A 487
VAL A 234
TYR A 201
 None
 1.36A 3r6wA-5dizA:
undetectable
3r6wB-5dizA:
undetectable		 3r6wA-5dizA:
18.34
3r6wB-5dizA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ghs SSDNA-SPECIFIC
EXONUCLEASE

(Thermococcus
kodakarensis) 		PF02272
(DHHA1) 		5 PHE A 448
GLY A 437
VAL A 361
PHE A 460
PHE A 456
 None
 1.42A 3r6wA-5ghsA:
2.9
3r6wB-5ghsA:
3.1		 3r6wA-5ghsA:
20.25
3r6wB-5ghsA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kvu ISOCITRATE
DEHYDROGENASE

(Mycobacterium
tuberculosis) 		PF03971
(IDH) 		5 ASN A 342
PHE A 343
GLY A 270
TYR A 238
PHE A 252
 None
 1.13A 3r6wA-5kvuA:
undetectable
3r6wB-5kvuA:
1.5		 3r6wA-5kvuA:
15.84
3r6wB-5kvuA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o33 KALIRIN

(Rattus
norvegicus) 		PF00621
(RhoGEF) 		5 PHE B1291
GLU B1245
VAL B1310
TYR B1373
PHE B1314
 None
 1.25A 3r6wA-5o33B:
undetectable
3r6wB-5o33B:
undetectable		 3r6wA-5o33B:
18.72
3r6wB-5o33B:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o9i TRANSCRIPTION
INITIATION FACTOR
IIB,TRANSCRIPTION
INITIATION FACTOR
IIB

(Methanocaldococcus
vulcanius) 		no annotation 5 PHE A 152
VAL A 187
PHE A  54
TYR A  58
PHE A 150
 None
 1.03A 3r6wA-5o9iA:
undetectable
3r6wB-5o9iA:
undetectable		 3r6wA-5o9iA:
19.67
3r6wB-5o9iA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5una 7SK SNRNA
METHYLPHOSPHATE
CAPPING ENZYME

(Homo sapiens) 		PF06859
(Bin3)
PF13847
(Methyltransf_31) 		5 ASN A 552
GLY A 455
PHE A 555
TYR A 490
PHE A 549
 None
 1.28A 3r6wA-5unaA:
undetectable
3r6wB-5unaA:
2.5		 3r6wA-5unaA:
21.55
3r6wB-5unaA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w0m TERMINAL
URIDYLYLTRANSFERASE
7

(Homo sapiens) 		PF00098
(zf-CCHC)
PF03828
(PAP_assoc) 		5 GLY A1317
PHE A 997
VAL A1004
PHE A1329
TYR A1328
 None
 1.47A 3r6wA-5w0mA:
undetectable
3r6wB-5w0mA:
undetectable		 3r6wA-5w0mA:
20.05
3r6wB-5w0mA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w76 ANCESTRAL ELOGATION
FACTOR N153

(synthetic
construct) 		no annotation 5 PHE A 305
GLY A 340
PHE A 323
VAL A 309
PHE A 375
 None
 1.47A 3r6wA-5w76A:
4.1
3r6wB-5w76A:
6.4		 3r6wA-5w76A:
15.20
3r6wB-5w76A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eu6 AMMONIUM TRANSPORTER

(Candidatus
Kuenenia
stuttgartiensis) 		no annotation 5 GLY A 166
PHE A 223
PHE A  67
PHE A  58
TYR A 136
 None
 1.21A 3r6wA-6eu6A:
undetectable
3r6wB-6eu6A:
undetectable		 3r6wA-6eu6A:
17.48
3r6wB-6eu6A:
17.48