SIMILAR PATTERNS OF AMINO ACIDS FOR 3R6I_A_JMSA332_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1c9w CHO REDUCTASE

(Cricetulus
griseus) 		PF00248
(Aldo_ket_red) 		5 TYR A  48
TRP A  79
HIS A 110
ASN A 160
TYR A 209
 NAP  A 350 (-4.8A)
None
NAP  A 350 (-4.0A)
NAP  A 350 (-3.2A)
NAP  A 350 (-3.5A)
 0.27A 3r6iA-1c9wA:
44.1		 3r6iA-1c9wA:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1q5m PROSTAGLANDIN-E2
9-REDUCTASE

(Oryctolagus
cuniculus) 		PF00248
(Aldo_ket_red) 		6 TYR A  24
TYR A  55
TRP A  86
HIS A 117
ASN A 167
TYR A 216
 None
NDP  A1003 (-4.9A)
None
NDP  A1003 (-4.3A)
NDP  A1003 (-3.4A)
NDP  A1003 (-3.2A)
 0.34A 3r6iA-1q5mA:
49.7		 3r6iA-1q5mA:
77.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1q5m PROSTAGLANDIN-E2
9-REDUCTASE

(Oryctolagus
cuniculus) 		PF00248
(Aldo_ket_red) 		5 TYR A  55
TRP A  86
HIS A 117
TYR A 216
TRP A 227
 NDP  A1003 (-4.9A)
None
NDP  A1003 (-4.3A)
NDP  A1003 (-3.2A)
None
 1.25A 3r6iA-1q5mA:
49.7		 3r6iA-1q5mA:
77.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1qwk ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1

(Caenorhabditis
elegans) 		PF00248
(Aldo_ket_red) 		6 TYR A  52
TRP A  83
HIS A 114
ASN A 154
TYR A 201
PHE A 299
 None
 0.61A 3r6iA-1qwkA:
40.3		 3r6iA-1qwkA:
39.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ral 3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE

(Rattus
norvegicus) 		PF00248
(Aldo_ket_red) 		6 LEU A  54
TYR A  55
TRP A  86
HIS A 117
ASN A 167
TYR A 216
 None
 0.70A 3r6iA-1ralA:
39.5		 3r6iA-1ralA:
70.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ral 3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE

(Rattus
norvegicus) 		PF00248
(Aldo_ket_red) 		5 TYR A  55
HIS A 117
MET A 120
ASN A 167
TYR A 216
 None
 1.34A 3r6iA-1ralA:
39.5		 3r6iA-1ralA:
70.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1z9a NAD(P)H-DEPENDENT
D-XYLOSE REDUCTASE

([Candida]
tenuis) 		PF00248
(Aldo_ket_red) 		5 TYR A  52
TRP A  83
HIS A 114
ASN A 170
TYR A 217
 None
None
NAD  A1350 (-4.4A)
NAD  A1350 (-3.3A)
NAD  A1350 (-3.2A)
 0.24A 3r6iA-1z9aA:
40.5		 3r6iA-1z9aA:
39.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2bgs ALDOSE REDUCTASE

(Hordeum vulgare) 		PF00248
(Aldo_ket_red) 		5 TYR A  60
TRP A  90
HIS A 121
ASN A 167
TYR A 214
 BCT  A1322 ( 4.4A)
None
BCT  A1322 ( 3.9A)
NDP  A1321 (-3.3A)
NDP  A1321 (-3.3A)
 0.23A 3r6iA-2bgsA:
39.8		 3r6iA-2bgsA:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2fvl ALDO-KETO REDUCTASE
FAMILY 1, MEMBER C4

(Homo sapiens) 		PF00248
(Aldo_ket_red) 		7 TYR A  24
LEU A  54
TYR A  55
TRP A  86
HIS A 117
MET A 120
ASN A 167
 None
None
NAP  A1001 (-4.7A)
None
NAP  A1001 (-4.4A)
None
NAP  A1001 (-3.1A)
 0.54A 3r6iA-2fvlA:
49.7		 3r6iA-2fvlA:
84.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2fvl ALDO-KETO REDUCTASE
FAMILY 1, MEMBER C4

(Homo sapiens) 		PF00248
(Aldo_ket_red) 		5 TYR A  24
LEU A  54
TYR A  55
TRP A  86
PHE A 310
 None
None
NAP  A1001 (-4.7A)
None
None
 0.96A 3r6iA-2fvlA:
49.7		 3r6iA-2fvlA:
84.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ipf (3(17)ALPHA-HYDROXYS
TEROID
DEHYDROGENASE)

(Mus musculus) 		PF00248
(Aldo_ket_red) 		6 TYR A  55
TRP A  86
HIS A 117
MET A 120
ASN A 167
TYR A 216
 FFA  A   3 ( 4.5A)
None
FFA  A   3 ( 4.1A)
None
NAP  A   1 (-3.3A)
NAP  A   1 (-3.5A)
 0.56A 3r6iA-2ipfA:
48.8		 3r6iA-2ipfA:
72.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ipj ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2

(Homo sapiens) 		PF00248
(Aldo_ket_red) 		5 TYR A  55
TRP A  86
HIS A 117
ASN A 167
TYR A 216
 FFA  A 325 ( 4.3A)
None
FFA  A 325 ( 3.8A)
NAP  A   1 (-3.1A)
NAP  A   1 (-3.2A)
 0.18A 3r6iA-2ipjA:
50.4		 3r6iA-2ipjA:
86.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2is7 ALDOSE REDUCTASE

(Homo sapiens) 		PF00248
(Aldo_ket_red) 		5 TYR A  48
TRP A  79
HIS A 110
ASN A 160
TYR A 209
 2CL  A 317 ( 4.5A)
None
2CL  A 317 ( 3.8A)
NAP  A 316 (-3.4A)
NAP  A 316 (-3.2A)
 0.29A 3r6iA-2is7A:
44.5		 3r6iA-2is7A:
48.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3cav 3-OXO-5-BETA-STEROID
4-DEHYDROGENASE

(Homo sapiens) 		PF00248
(Aldo_ket_red) 		6 TYR A  26
TYR A  58
TRP A  89
MET A 123
ASN A 170
TYR A 219
 CI2  A 328 ( 4.0A)
CI2  A 328 ( 4.5A)
None
None
NAP  A 327 (-3.6A)
NAP  A 327 (-3.4A)
 0.58A 3r6iA-3cavA:
46.0		 3r6iA-3cavA:
55.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d1c FLAVIN-CONTAINING
PUTATIVE
MONOOXYGENASE

(Staphylococcus
aureus) 		PF13738
(Pyr_redox_3) 		5 LEU A  93
TYR A  89
SER A  70
PHE A 322
PHE A 326
 None
None
None
FAD  A 500 ( 4.8A)
None
 1.49A 3r6iA-3d1cA:
undetectable		 3r6iA-3d1cA:
21.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3h7r ALDO-KETO REDUCTASE

(Arabidopsis
thaliana) 		PF00248
(Aldo_ket_red) 		6 TYR A  24
TYR A  48
TRP A  79
HIS A 110
ASN A 155
TYR A 202
 ACT  A 501 ( 4.0A)
ACT  A 501 ( 4.3A)
None
ACT  A 501 ( 4.0A)
NAP  A 401 (-3.4A)
NAP  A 401 (-3.1A)
 0.32A 3r6iA-3h7rA:
40.5		 3r6iA-3h7rA:
39.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3h7u ALDO-KETO REDUCTASE

(Arabidopsis
thaliana) 		PF00248
(Aldo_ket_red) 		5 TYR A  52
HIS A 114
ASN A 159
TYR A 206
PHE A 295
 ACT  A 501 ( 4.4A)
ACT  A 501 ( 3.8A)
NAP  A 401 (-3.3A)
NAP  A 401 (-3.2A)
None
 1.18A 3r6iA-3h7uA:
40.9		 3r6iA-3h7uA:
40.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3h7u ALDO-KETO REDUCTASE

(Arabidopsis
thaliana) 		PF00248
(Aldo_ket_red) 		5 TYR A  52
TRP A  83
HIS A 114
ASN A 159
TYR A 206
 ACT  A 501 ( 4.4A)
None
ACT  A 501 ( 3.8A)
NAP  A 401 (-3.3A)
NAP  A 401 (-3.2A)
 0.26A 3r6iA-3h7uA:
40.9		 3r6iA-3h7uA:
40.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3krb ALDOSE REDUCTASE

(Giardia
intestinalis) 		PF00248
(Aldo_ket_red) 		5 TYR A  40
TRP A  73
HIS A 104
ASN A 156
TYR A 203
 UNX  A 402 (-4.4A)
None
UNX  A 402 (-4.1A)
NAP  A 400 (-3.4A)
NAP  A 400 (-3.2A)
 0.29A 3r6iA-3krbA:
37.5		 3r6iA-3krbA:
36.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3krb ALDOSE REDUCTASE

(Giardia
intestinalis) 		PF00248
(Aldo_ket_red) 		5 TYR A  40
TRP A  73
HIS A 104
TYR A 203
PHE A 306
 UNX  A 402 (-4.4A)
None
UNX  A 402 (-4.1A)
NAP  A 400 (-3.2A)
None
 1.00A 3r6iA-3krbA:
37.5		 3r6iA-3krbA:
36.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ln3 DIHYDRODIOL
DEHYDROGENASE

(Mus musculus) 		PF00248
(Aldo_ket_red) 		6 TYR A  24
TYR A  55
TRP A  86
HIS A 117
ASN A 167
TYR A 216
 MLY  A  25 (-3.6A)
NAD  A 327 ( 4.7A)
None
MRD  A 328 ( 3.9A)
NAD  A 327 (-3.3A)
NAD  A 327 (-3.4A)
 0.34A 3r6iA-3ln3A:
47.5		 3r6iA-3ln3A:
64.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3o3r ALDO-KETO REDUCTASE
FAMILY 1, MEMBER B7

(Rattus
norvegicus) 		PF00248
(Aldo_ket_red) 		5 TYR A  49
TRP A  80
HIS A 111
ASN A 161
TYR A 210
 NAP  A 317 (-4.9A)
None
NAP  A 317 (-4.3A)
NAP  A 317 (-3.1A)
NAP  A 317 (-3.3A)
 0.27A 3r6iA-3o3rA:
43.0		 3r6iA-3o3rA:
45.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3up8 PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE B

(Sinorhizobium
meliloti) 		PF00248
(Aldo_ket_red) 		5 TYR A  47
TRP A  74
HIS A 105
ASN A 136
TYR A 183
 ACT  A 276 (-4.6A)
None
ACT  A 276 (-3.9A)
None
ACT  A 276 (-3.7A)
 0.37A 3r6iA-3up8A:
36.6		 3r6iA-3up8A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE

(Gluconobacter
oxydans) 		PF00248
(Aldo_ket_red) 		5 LEU A  57
TYR A  58
TRP A  81
HIS A 112
ASN A 144
 None
 0.55A 3r6iA-3wbxA:
36.1		 3r6iA-3wbxA:
35.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3wcz ALDO-KETO REDUCTASE
2E

(Bombyx mori) 		PF00248
(Aldo_ket_red) 		5 TYR A  58
TRP A  89
HIS A 120
ASN A 159
TYR A 206
 CIT  A 406 ( 3.2A)
None
NAP  A 401 (-4.0A)
NAP  A 401 ( 2.8A)
NAP  A 401 (-3.2A)
 0.23A 3r6iA-3wczA:
42.7		 3r6iA-3wczA:
40.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3wg6 CONJUGATED
POLYKETONE REDUCTASE
C1

(Candida
parapsilosis) 		PF00248
(Aldo_ket_red) 		5 TYR A  60
HIS A 125
ASN A 161
TYR A 211
PHE A 296
 NDP  A3001 (-4.7A)
NDP  A3001 (-4.2A)
NDP  A3001 (-3.1A)
NDP  A3001 (-3.3A)
NDP  A3001 (-3.7A)
 0.57A 3r6iA-3wg6A:
34.5		 3r6iA-3wg6A:
32.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4fzi PROSTAGLANDIN F
SYNTHASE

(Trypanosoma
cruzi) 		PF00248
(Aldo_ket_red) 		5 TYR A  53
TRP A  80
HIS A 111
ASN A 141
PHE A 276
 GLU  A 301 (-4.4A)
None
GLU  A 301 (-3.8A)
GLU  A 301 (-3.7A)
None
 0.67A 3r6iA-4fziA:
37.1		 3r6iA-4fziA:
35.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4h8n CONJUGATED
POLYKETONE REDUCTASE
C2

(Candida
parapsilosis) 		PF00248
(Aldo_ket_red) 		5 TYR A  63
HIS A 125
SER A 126
ASN A 162
PHE A 299
 NDP  A3001 (-4.7A)
NDP  A3001 (-4.5A)
None
NDP  A3001 (-3.3A)
NDP  A3001 ( 4.2A)
 0.29A 3r6iA-4h8nA:
31.2		 3r6iA-4h8nA:
32.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hbk ALDO-KETO REDUCTASE
FAMILY 1, MEMBER B4
(ALDOSE REDUCTASE)

(Schistosoma
japonicum) 		PF00248
(Aldo_ket_red) 		6 TYR A  48
TRP A  79
HIS A 110
ASN A 160
TYR A 207
PHE A 293
 None
 0.84A 3r6iA-4hbkA:
41.5		 3r6iA-4hbkA:
39.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ijr D-ARABINOSE
DEHYDROGENASE
[NAD(P)+] HEAVY
CHAIN

(Saccharomyces
cerevisiae) 		PF00248
(Aldo_ket_red) 		5 TYR A  71
HIS A 131
ASN A 193
TYR A 240
PHE A 325
 NDP  A 401 (-4.7A)
NDP  A 401 (-3.9A)
NDP  A 401 (-3.3A)
NDP  A 401 (-3.3A)
None
 0.99A 3r6iA-4ijrA:
38.1		 3r6iA-4ijrA:
34.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ijr D-ARABINOSE
DEHYDROGENASE
[NAD(P)+] HEAVY
CHAIN

(Saccharomyces
cerevisiae) 		PF00248
(Aldo_ket_red) 		5 TYR A  71
TRP A 102
HIS A 131
ASN A 193
TYR A 240
 NDP  A 401 (-4.7A)
None
NDP  A 401 (-3.9A)
NDP  A 401 (-3.3A)
NDP  A 401 (-3.3A)
 0.46A 3r6iA-4ijrA:
38.1		 3r6iA-4ijrA:
34.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n01 PERIPLASMIC BINDING
PROTEIN

(Veillonella
parvula) 		PF01497
(Peripla_BP_2) 		5 LEU A 172
TRP A 150
SER A 154
MET A 155
ASN A 165
 None
 1.50A 3r6iA-4n01A:
undetectable		 3r6iA-4n01A:
22.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4q3m MGS-M4

(unidentified) 		PF00248
(Aldo_ket_red) 		6 TYR A  48
TRP A  75
HIS A 106
ASN A 137
TYR A 184
PHE A 266
 None
 0.51A 3r6iA-4q3mA:
39.0		 3r6iA-4q3mA:
38.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5az0 UNCHARACTERIZED
PROTEIN

(Bombyx mori) 		PF00248
(Aldo_ket_red) 		6 TYR A  75
TRP A 106
HIS A 137
MET A 140
ASN A 176
TYR A 223
 ACT  A 405 (-4.7A)
None
None
None
None
None
 0.86A 3r6iA-5az0A:
40.4		 3r6iA-5az0A:
32.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dan 2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE

(Thermotoga
maritima) 		PF00248
(Aldo_ket_red) 		5 TYR A  58
TRP A  86
HIS A 117
ASN A 148
TYR A 198
 NAP  A 301 (-4.9A)
None
NAP  A 301 (-4.3A)
NAP  A 301 (-3.5A)
NAP  A 301 (-3.3A)
 0.57A 3r6iA-5danA:
32.2		 3r6iA-5danA:
35.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5jgy ALDOSE REDUCTASE,
AKR4C13

(Zea mays) 		PF00248
(Aldo_ket_red) 		5 TYR A  59
TRP A  89
HIS A 120
ASN A 166
TYR A 213
 6KB  A 401 ( 4.6A)
None
6KB  A 401 ( 4.0A)
6KB  A 401 (-3.5A)
6KB  A 401 (-3.4A)
 0.26A 3r6iA-5jgyA:
39.9		 3r6iA-5jgyA:
38.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ket ALDO-KETO REDUCTASE
1

(Coptotermes
gestroi) 		PF00248
(Aldo_ket_red) 		5 TYR A  52
HIS A 114
ASN A 167
TYR A 214
PHE A 314
 NAP  A 400 (-4.8A)
NAP  A 400 (-4.3A)
NAP  A 400 (-3.3A)
NAP  A 400 (-3.6A)
NAP  A 400 (-4.6A)
 0.51A 3r6iA-5ketA:
42.2		 3r6iA-5ketA:
39.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5liy ALDO-KETO REDUCTASE
FAMILY 1 MEMBER B10

(Homo sapiens) 		PF00248
(Aldo_ket_red) 		5 TYR X  49
TRP X  80
HIS X 111
ASN X 161
TYR X 210
 DQP  X 402 ( 4.0A)
None
DQP  X 402 ( 4.1A)
NAP  X 401 (-3.2A)
NAP  X 401 ( 3.1A)
 0.31A 3r6iA-5liyX:
43.7		 3r6iA-5liyX:
46.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tfz DIMETHYLSULFONIOPROP
IONATE LYASE DDDK

(Candidatus
Pelagibacter
ubique) 		PF07883
(Cupin_2) 		6 LEU A  53
TYR A  21
HIS A  56
TRP A 110
PHE A 117
PHE A 112
 7BC  A 202 (-4.9A)
None
NI  A 201 ( 3.8A)
7BC  A 202 ( 4.3A)
7BC  A 202 ( 4.9A)
None
 1.40A 3r6iA-5tfzA:
undetectable		 3r6iA-5tfzA:
19.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6f2u ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3

(Homo sapiens) 		no annotation 5 TYR A  24
LEU A  54
TYR A  55
HIS A 117
SER A  87
 CJ2  A 402 (-4.2A)
None
CJ2  A 402 ( 4.1A)
CJ2  A 402 ( 3.8A)
None
 1.47A 3r6iA-6f2uA:
50.4		 3r6iA-6f2uA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6f2u ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3

(Homo sapiens) 		no annotation 8 TYR A  24
LEU A  54
TYR A  55
HIS A 117
SER A 118
ASN A 167
TRP A 227
PHE A 306
 CJ2  A 402 (-4.2A)
None
CJ2  A 402 ( 4.1A)
CJ2  A 402 ( 3.8A)
CJ2  A 402 ( 3.7A)
NAP  A 401 ( 3.3A)
CJ2  A 402 ( 4.8A)
CJ2  A 402 (-3.8A)
 1.04A 3r6iA-6f2uA:
50.4		 3r6iA-6f2uA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6f2u ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3

(Homo sapiens) 		no annotation 9 TYR A  24
LEU A  54
TYR A  55
TRP A  86
HIS A 117
SER A 118
ASN A 167
TYR A 216
TRP A 227
 CJ2  A 402 (-4.2A)
None
CJ2  A 402 ( 4.1A)
None
CJ2  A 402 ( 3.8A)
CJ2  A 402 ( 3.7A)
NAP  A 401 ( 3.3A)
NAP  A 401 ( 3.2A)
CJ2  A 402 ( 4.8A)
 0.48A 3r6iA-6f2uA:
50.4		 3r6iA-6f2uA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6f2u ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3

(Homo sapiens) 		no annotation 9 TYR A  24
LEU A  54
TYR A  55
TRP A  86
HIS A 117
SER A 118
MET A 120
ASN A 167
TYR A 216
 CJ2  A 402 (-4.2A)
None
CJ2  A 402 ( 4.1A)
None
CJ2  A 402 ( 3.8A)
CJ2  A 402 ( 3.7A)
CJ2  A 402 ( 4.7A)
NAP  A 401 ( 3.3A)
NAP  A 401 ( 3.2A)
 0.27A 3r6iA-6f2uA:
50.4		 3r6iA-6f2uA:
100.00