SIMILAR PATTERNS OF AMINO ACIDS FOR 3QXV_D_MTXD2000_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1am2 MXE GYRA INTEIN

(Mycobacterium
xenopi) 		no annotation 3 LEU A  89
ARG A 107
ASN A  43
 None
 0.70A 3qxvD-1am2A:
undetectable		 3qxvD-1am2A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cu1 PROTEIN
(PROTEASE/HELICASE
NS3)

(Hepacivirus C) 		PF02907
(Peptidase_S29)
PF07652
(Flavi_DEAD) 		3 LEU A 144
ARG A  92
ASN A  49
 None
 0.77A 3qxvD-1cu1A:
undetectable		 3qxvD-1cu1A:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e3h GUANOSINE
PENTAPHOSPHATE
SYNTHETASE

(Streptomyces
antibioticus) 		PF00013
(KH_1)
PF01138
(RNase_PH)
PF03726
(PNPase) 		3 LEU A 474
ARG A 433
ASN A 403
 None
 0.62A 3qxvD-1e3hA:
undetectable		 3qxvD-1e3hA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fng PROTEIN (MHC CLASS
II I-EK, BETA CHAIN)

(Mus musculus) 		PF00969
(MHC_II_beta)
PF07654
(C1-set) 		3 LEU B  38
ARG B  72
ASN B   5
 None
 0.62A 3qxvD-1fngB:
5.8		 3qxvD-1fngB:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gaj HIGH-AFFINITY
BRANCHED CHAIN AMINO
ACID TRANSPORT
ATP-BINDING PROTEIN

(Methanocaldococcus
jannaschii) 		PF00005
(ABC_tran) 		3 LEU A   8
ARG A  86
ASN A  73
 None
PEG  A 600 ( 4.6A)
None
 0.73A 3qxvD-1gajA:
undetectable		 3qxvD-1gajA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h0h FORMATE
DEHYDROGENASE
SUBUNIT ALPHA

(Desulfovibrio
gigas) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		3 LEU A 391
ARG A 172
ASN A 404
 None
 0.58A 3qxvD-1h0hA:
undetectable		 3qxvD-1h0hA:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h3g CYCLOMALTODEXTRINASE

(Flavobacterium
sp. 92) 		PF00128
(Alpha-amylase)
PF09087
(Cyc-maltodext_N)
PF10438
(Cyc-maltodext_C) 		3 LEU A 398
ARG A 508
ASN A 436
 None
 0.72A 3qxvD-1h3gA:
3.5		 3qxvD-1h3gA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i2o TRANSALDOLASE B

(Escherichia
coli) 		PF00923
(TAL_FSA) 		3 LEU A  83
ARG A 114
ASN A 126
 None
 0.76A 3qxvD-1i2oA:
undetectable		 3qxvD-1i2oA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nrk YGFZ PROTEIN

(Escherichia
coli) 		PF01571
(GCV_T) 		3 LEU A 162
ARG A  91
ASN A  72
 SO4  A 400 (-4.3A)
None
None
 0.76A 3qxvD-1nrkA:
undetectable		 3qxvD-1nrkA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nvt SHIKIMATE
5'-DEHYDROGENASE

(Methanocaldococcus
jannaschii) 		PF01488
(Shikimate_DH)
PF08501
(Shikimate_dh_N) 		3 LEU A 229
ARG A 116
ASN A 109
 NAP  A 288 (-4.4A)
None
None
 0.75A 3qxvD-1nvtA:
undetectable		 3qxvD-1nvtA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ohf NUDAURELIA CAPENSIS
OMEGA VIRUS CAPSID
PROTEIN

(Nudaurelia
capensis omega
virus) 		PF03566
(Peptidase_A21) 		3 LEU A 393
ARG A 409
ASN A 364
 None
 0.62A 3qxvD-1ohfA:
2.3		 3qxvD-1ohfA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r8w GLYCEROL DEHYDRATASE

(Clostridium
butyricum) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		3 LEU A 745
ARG A 673
ASN A 737
 None
 0.74A 3qxvD-1r8wA:
undetectable		 3qxvD-1r8wA:
10.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sgj CITRATE LYASE, BETA
SUBUNIT

(Deinococcus
radiodurans) 		PF03328
(HpcH_HpaI) 		3 LEU A  25
ARG A  74
ASN A  17
 None
OAA  A 285 ( 2.3A)
None
 0.71A 3qxvD-1sgjA:
undetectable		 3qxvD-1sgjA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1woi AGMATINASE

(Deinococcus
radiodurans) 		PF00491
(Arginase) 		3 LEU A 181
ARG A 164
ASN A 159
 None
 0.67A 3qxvD-1woiA:
undetectable		 3qxvD-1woiA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xx4 3,2-TRANS-ENOYL-COA
ISOMERASE,
MITOCHONDRIAL

(Rattus
norvegicus) 		PF00378
(ECH_1) 		3 LEU A  95
ARG A 257
ASN A 179
 None
 0.76A 3qxvD-1xx4A:
undetectable		 3qxvD-1xx4A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ayi AMINOPEPTIDASE T

(Thermus
thermophilus) 		PF02073
(Peptidase_M29) 		3 LEU A 219
ARG A 286
ASN A 371
 None
 0.64A 3qxvD-2ayiA:
undetectable		 3qxvD-2ayiA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iya OLEANDOMYCIN
GLYCOSYLTRANSFERASE

(Streptomyces
antibioticus) 		PF00201
(UDPGT) 		3 LEU A 259
ARG A 293
ASN A  27
 None
None
UDP  A1424 (-4.0A)
 0.71A 3qxvD-2iyaA:
undetectable		 3qxvD-2iyaA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2or7 T-CELL
IMMUNOGLOBULIN AND
MUCIN
DOMAIN-CONTAINING
PROTEIN 2

(Mus musculus) 		PF07686
(V-set) 		3 LEU A  17
ARG A  45
ASN A  60
 None
 0.78A 3qxvD-2or7A:
9.5		 3qxvD-2or7A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p57 GTPASE-ACTIVATING
PROTEIN ZNF289

(Homo sapiens) 		PF01412
(ArfGap) 		3 LEU A  45
ARG A 115
ASN A 103
 None
 0.66A 3qxvD-2p57A:
undetectable		 3qxvD-2p57A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q2r GLUCOKINASE 1,
PUTATIVE

(Trypanosoma
cruzi) 		PF02685
(Glucokinase) 		3 LEU A 107
ARG A  54
ASN A 355
 None
 0.56A 3qxvD-2q2rA:
undetectable		 3qxvD-2q2rA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qa1 POLYKETIDE OXYGENASE
PGAE

(Streptomyces
sp. PGA64) 		PF01494
(FAD_binding_3) 		3 LEU A  60
ARG A 390
ASN A 289
 None
None
FAD  A 500 (-3.5A)
 0.57A 3qxvD-2qa1A:
undetectable		 3qxvD-2qa1A:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qa2 POLYKETIDE OXYGENASE
CABE

(Streptomyces) 		PF01494
(FAD_binding_3) 		3 LEU A  60
ARG A 390
ASN A 289
 None
None
FAD  A 500 (-3.6A)
 0.58A 3qxvD-2qa2A:
undetectable		 3qxvD-2qa2A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qqu BETA-FRUCTOFURANOSID
ASE

(Arabidopsis
thaliana) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		3 LEU A 515
ARG A 480
ASN A 529
 None
 0.76A 3qxvD-2qquA:
undetectable		 3qxvD-2qquA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r3v MEVALONATE KINASE

(Homo sapiens) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C) 		3 LEU A   7
ARG A 388
ASN A  34
 None
 0.68A 3qxvD-2r3vA:
undetectable		 3qxvD-2r3vA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ywk PUTATIVE RNA-BINDING
PROTEIN 11

(Homo sapiens) 		PF00076
(RRM_1) 		3 LEU A  26
ARG A  78
ASN A  71
 None
 0.71A 3qxvD-2ywkA:
undetectable		 3qxvD-2ywkA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yxx DIAMINOPIMELATE
DECARBOXYLASE

(Thermotoga
maritima) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		3 LEU A 260
ARG A 285
ASN A 349
 None
 0.75A 3qxvD-2yxxA:
undetectable		 3qxvD-2yxxA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yyl 4-HYDROXYPHENYLACETA
TE-3-HYDROXYLASE

(Thermus
thermophilus) 		PF03241
(HpaB)
PF11794
(HpaB_N) 		3 LEU A 452
ARG A 338
ASN A 282
 None
 0.69A 3qxvD-2yylA:
undetectable		 3qxvD-2yylA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ayx MEMBRANE-BOUND
HYDROGENASE LARGE
SUBUNIT
MEMBRANE-BOUND
HYDROGENASE SMALL
SUBUNIT

(Hydrogenovibrio
marinus) 		PF00374
(NiFeSe_Hases)
PF01058
(Oxidored_q6)
PF14720
(NiFe_hyd_SSU_C) 		3 LEU A 265
ARG B 243
ASN A 255
 None
 0.77A 3qxvD-3ayxA:
undetectable		 3qxvD-3ayxA:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE

(Mus musculus) 		PF05889
(SepSecS) 		3 LEU A 320
ARG A  86
ASN A  64
 EDO  A 502 (-3.9A)
None
None
 0.68A 3qxvD-3bc8A:
undetectable		 3qxvD-3bc8A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE

(Mus musculus) 		PF05889
(SepSecS) 		3 LEU A 408
ARG A 362
ASN A 435
 None
 0.69A 3qxvD-3bc8A:
undetectable		 3qxvD-3bc8A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3btp SINGLE-STRAND
DNA-BINDING PROTEIN

(Agrobacterium
fabrum) 		PF07229
(VirE2) 		3 LEU A 264
ARG A 113
ASN A 135
 None
 0.72A 3qxvD-3btpA:
undetectable		 3qxvD-3btpA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3but UNCHARACTERIZED
PROTEIN AF_0446

(Archaeoglobus
fulgidus) 		PF03168
(LEA_2) 		3 LEU A  73
ARG A 116
ASN A  44
 None
 0.76A 3qxvD-3butA:
undetectable		 3qxvD-3butA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cux MALATE SYNTHASE

(Bacillus
anthracis) 		PF01274
(Malate_synthase) 		3 LEU A 160
ARG A  97
ASN A 119
 None
 0.78A 3qxvD-3cuxA:
undetectable		 3qxvD-3cuxA:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3a BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		PF01301
(Glyco_hydro_35) 		3 LEU A 156
ARG A 142
ASN A  81
 None
 0.73A 3qxvD-3d3aA:
2.8		 3qxvD-3d3aA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dez OROTATE
PHOSPHORIBOSYLTRANSF
ERASE

(Streptococcus
mutans) 		PF00156
(Pribosyltran) 		3 LEU A 194
ARG A   9
ASN A 175
 None
 0.64A 3qxvD-3dezA:
undetectable		 3qxvD-3dezA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ec1 YQEH GTPASE

(Geobacillus
stearothermophilus) 		PF01926
(MMR_HSR1) 		3 LEU A 267
ARG A 365
ASN A 346
 None
 0.75A 3qxvD-3ec1A:
undetectable		 3qxvD-3ec1A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ec1 YQEH GTPASE

(Geobacillus
stearothermophilus) 		PF01926
(MMR_HSR1) 		3 LEU A 352
ARG A 365
ASN A 346
 None
 0.78A 3qxvD-3ec1A:
undetectable		 3qxvD-3ec1A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eh2 PROTEIN TRANSPORT
PROTEIN SEC24C

(Homo sapiens) 		PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS) 		3 LEU A 660
ARG A 605
ASN A 522
 None
 0.66A 3qxvD-3eh2A:
1.3		 3qxvD-3eh2A:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax) 		PF01048
(PNP_UDP_1) 		3 LEU A  35
ARG A 226
ASN A 221
 None
 0.66A 3qxvD-3emvA:
undetectable		 3qxvD-3emvA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fy4 6-4 PHOTOLYASE

(Arabidopsis
thaliana) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		3 LEU A 226
ARG A 272
ASN A 280
 None
 0.70A 3qxvD-3fy4A:
undetectable		 3qxvD-3fy4A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gf8 PUTATIVE
POLYSACCHARIDE
BINDING PROTEINS
(DUF1812)

(Bacteroides
thetaiotaomicron) 		PF08842
(Mfa2) 		3 LEU A 266
ARG A 168
ASN A 199
 None
 0.46A 3qxvD-3gf8A:
2.3		 3qxvD-3gf8A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gse MENAQUINONE-SPECIFIC
ISOCHORISMATE
SYNTHASE

(Yersinia pestis) 		PF00425
(Chorismate_bind) 		3 LEU A 331
ARG A 259
ASN A 303
 None
SO4  A 456 (-3.0A)
None
 0.75A 3qxvD-3gseA:
undetectable		 3qxvD-3gseA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0g DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB1
DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2

(Schizosaccharomyces
pombe) 		PF00562
(RNA_pol_Rpb2_6)
PF00623
(RNA_pol_Rpb1_2)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		3 LEU B1140
ARG A 845
ASN A 451
 None
 0.75A 3qxvD-3h0gB:
undetectable		 3qxvD-3h0gB:
7.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hg7 D-ISOMER SPECIFIC
2-HYDROXYACID
DEHYDROGENASE FAMILY
PROTEIN

(Aeromonas
salmonicida) 		PF02826
(2-Hacid_dh_C) 		3 LEU A 262
ARG A 245
ASN A 236
 None
 0.66A 3qxvD-3hg7A:
undetectable		 3qxvD-3hg7A:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 SMALL NUCLEAR
RIBONUCLEOPROTEIN F
SMALL NUCLEAR
RIBONUCLEOPROTEIN SM
D2

(Schizosaccharomyces
pombe) 		PF01423
(LSM) 		3 LEU I  64
ARG G  48
ASN G  65
 None
U  C 103 ( 2.9A)
U  C 101 ( 3.2A)
 0.71A 3qxvD-3jb9I:
undetectable		 3qxvD-3jb9I:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jxa CONTACTIN 4

(Mus musculus) 		PF07679
(I-set)
PF13927
(Ig_3) 		3 LEU A 214
ARG A 170
ASN A 252
 None
 0.58A 3qxvD-3jxaA:
7.8		 3qxvD-3jxaA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l4k DNA TOPOISOMERASE 2

(Saccharomyces
cerevisiae) 		PF00521
(DNA_topoisoIV)
PF01751
(Toprim)
PF16898
(TOPRIM_C) 		3 LEU A 790
ARG A 854
ASN A 845
 None
 0.64A 3qxvD-3l4kA:
undetectable		 3qxvD-3l4kA:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lm3 UNCHARACTERIZED
PROTEIN

(Parabacteroides
distasonis) 		PF12979
(DUF3863)
PF12980
(DUF3864) 		3 LEU A 399
ARG A 469
ASN A 392
 None
 0.66A 3qxvD-3lm3A:
undetectable		 3qxvD-3lm3A:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lpp SUCRASE-ISOMALTASE

(Homo sapiens) 		PF00088
(Trefoil)
PF01055
(Glyco_hydro_31)
PF16863
(NtCtMGAM_N) 		3 LEU A 888
ARG A 858
ASN A 863
 None
 0.56A 3qxvD-3lppA:
undetectable		 3qxvD-3lppA:
9.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mru AMINOACYL-HISTIDINE
DIPEPTIDASE

(Vibrio
alginolyticus) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		3 LEU A 383
ARG A 369
ASN A 230
 None
 0.73A 3qxvD-3mruA:
undetectable		 3qxvD-3mruA:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mw6 UNCHARACTERIZED
PROTEIN NMB1681

(Neisseria
meningitidis) 		PF04352
(ProQ) 		3 LEU A  52
ARG A  87
ASN A  92
 None
 0.69A 3qxvD-3mw6A:
undetectable		 3qxvD-3mw6A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oc5 TOXIN COREGULATED
PILUS BIOSYNTHESIS
PROTEIN F

(Vibrio cholerae) 		PF06340
(TcpF) 		3 LEU A 297
ARG A 112
ASN A 145
 None
 0.74A 3qxvD-3oc5A:
3.4		 3qxvD-3oc5A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pt5 NANS (YJHS), A
9-O-ACETYL
N-ACETYLNEURAMINIC
ACID ESTERASE

(Escherichia
coli) 		PF03629
(SASA) 		3 LEU A 173
ARG A  40
ASN A 167
 None
 0.78A 3qxvD-3pt5A:
undetectable		 3qxvD-3pt5A:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s5k FALCILYSIN

(Plasmodium
falciparum) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
PF08367
(M16C_assoc) 		3 LEU A 912
ARG A 854
ASN A 894
 None
 0.72A 3qxvD-3s5kA:
undetectable		 3qxvD-3s5kA:
6.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sun DNA POLYMERASE

(Escherichia
virus RB69) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		3 LEU A 373
ARG A 384
ASN A 582
 None
 0.77A 3qxvD-3sunA:
undetectable		 3qxvD-3sunA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ubd RIBOSOMAL PROTEIN S6
KINASE ALPHA-3

(Mus musculus) 		PF00069
(Pkinase) 		3 LEU A 145
ARG A 110
ASN A 198
 SL0  A 400 ( 4.8A)
None
None
 0.75A 3qxvD-3ubdA:
undetectable		 3qxvD-3ubdA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wpe TOLL-LIKE RECEPTOR 9

(Bos taurus) 		PF13516
(LRR_6)
PF13855
(LRR_8) 		3 LEU A 598
ARG A 657
ASN A 606
 None
 0.73A 3qxvD-3wpeA:
undetectable		 3qxvD-3wpeA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b67 L-ORNITHINE N5
MONOOXYGENASE

(Aspergillus
fumigatus) 		PF13434
(K_oxygenase) 		3 LEU A 471
ARG A 144
ASN A 323
 None
FAD  A1492 ( 3.8A)
NAP  A1493 ( 2.9A)
 0.64A 3qxvD-4b67A:
undetectable		 3qxvD-4b67A:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4blf SINGLE-STRAND
DNA-BINDING PROTEIN

(Agrobacterium
tumefaciens) 		PF07229
(VirE2) 		3 LEU A 264
ARG A 113
ASN A 135
 None
 0.74A 3qxvD-4blfA:
undetectable		 3qxvD-4blfA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cu9 BETA-GALACTOSIDASE

(Streptococcus
pneumoniae) 		no annotation 3 LEU A1896
ARG A1976
ASN A1863
 None
 0.72A 3qxvD-4cu9A:
2.2		 3qxvD-4cu9A:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e5v PUTATIVE THUA-LIKE
PROTEIN

(Parabacteroides
merdae) 		PF06283
(ThuA) 		3 LEU A 231
ARG A 202
ASN A 120
 None
None
EDO  A 403 (-3.3A)
 0.78A 3qxvD-4e5vA:
undetectable		 3qxvD-4e5vA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fzw 2,3-DEHYDROADIPYL-CO
A HYDRATASE

(Escherichia
coli) 		PF00378
(ECH_1) 		3 LEU A  15
ARG A  87
ASN A  92
 None
 0.58A 3qxvD-4fzwA:
undetectable		 3qxvD-4fzwA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gyp GLUCARATE
DEHYDRATASE-RELATED
PROTEIN

(Escherichia
coli) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 LEU C 127
ARG C  78
ASN C  45
 None
 0.76A 3qxvD-4gypC:
undetectable		 3qxvD-4gypC:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h5y LIDA PROTEIN,
SUBSTRATE OF THE
DOT/ICM SYSTEM

(Legionella
pneumophila) 		no annotation 3 LEU A  93
ARG A 141
ASN A 124
 None
 0.73A 3qxvD-4h5yA:
undetectable		 3qxvD-4h5yA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i6f SERINE/THREONINE-PRO
TEIN KINASE PLK2

(Homo sapiens) 		PF00069
(Pkinase) 		3 LEU A 137
ARG A 204
ASN A 210
 None
 0.78A 3qxvD-4i6fA:
undetectable		 3qxvD-4i6fA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iv9 TRYPTOPHAN
2-MONOOXYGENASE

(Pseudomonas
savastanoi) 		PF01593
(Amino_oxidase) 		3 LEU A 167
ARG A 202
ASN A 208
 None
 0.73A 3qxvD-4iv9A:
undetectable		 3qxvD-4iv9A:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kjv E3 UBIQUITIN-PROTEIN
LIGASE XIAP

(Homo sapiens) 		PF00653
(BIR) 		3 LEU A 189
ARG A 222
ASN A 226
 None
1RK  A 502 (-4.2A)
None
 0.67A 3qxvD-4kjvA:
undetectable		 3qxvD-4kjvA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mzy NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE

(Enterococcus
faecalis) 		PF04095
(NAPRTase) 		3 LEU A 447
ARG A 147
ASN A 110
 None
None
GOL  A 513 ( 4.0A)
 0.68A 3qxvD-4mzyA:
undetectable		 3qxvD-4mzyA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n9x PUTATIVE
MONOOXYGENASE

(Pectobacterium
atrosepticum) 		PF01494
(FAD_binding_3) 		3 LEU A 117
ARG A  62
ASN A 303
 None
 0.70A 3qxvD-4n9xA:
undetectable		 3qxvD-4n9xA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qxl FLAGELLAR PROTEIN
FLHE

(Salmonella
enterica) 		PF06366
(FlhE) 		3 LEU A  58
ARG A  30
ASN A 112
 None
 0.65A 3qxvD-4qxlA:
undetectable		 3qxvD-4qxlA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ri6 PHI CLASS
GLUTATHIONE
TRANSFERASE GSTF1

(Populus tremula
x Populus
tremuloides) 		PF00043
(GST_C)
PF02798
(GST_N) 		3 LEU A 170
ARG A 155
ASN A 193
 None
 0.48A 3qxvD-4ri6A:
undetectable		 3qxvD-4ri6A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rqo L-SERINE DEHYDRATASE

(Legionella
pneumophila) 		PF03313
(SDH_alpha)
PF03315
(SDH_beta) 		3 LEU A 236
ARG A 399
ASN A 279
 None
SF4  A 500 ( 4.6A)
None
 0.65A 3qxvD-4rqoA:
undetectable		 3qxvD-4rqoA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u63 DNA PHOTOLYASE

(Agrobacterium
fabrum) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		3 LEU A  59
ARG A 101
ASN A  21
 None
 0.63A 3qxvD-4u63A:
undetectable		 3qxvD-4u63A:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wz9 AGAP004809-PA

(Anopheles
gambiae) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		3 LEU A 193
ARG A 341
ASN A 334
 None
 0.65A 3qxvD-4wz9A:
undetectable		 3qxvD-4wz9A:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x4j PUTATIVE OXYGENASE

(Amycolatopsis
orientalis) 		PF01494
(FAD_binding_3) 		3 LEU A  60
ARG A 390
ASN A 289
 None
None
FAD  A 503 (-3.4A)
 0.71A 3qxvD-4x4jA:
undetectable		 3qxvD-4x4jA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgc ORIGIN RECOGNITION
COMPLEX SUBUNIT 1

(Drosophila
melanogaster) 		PF00004
(AAA)
PF09079
(Cdc6_C) 		3 LEU A 905
ARG A 692
ASN A 718
 None
 0.60A 3qxvD-4xgcA:
undetectable		 3qxvD-4xgcA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yfa PROTEIN RELATED TO
PENICILLIN ACYLASE

(Acidovorax sp.
MR-S7) 		PF01804
(Penicil_amidase) 		3 LEU A  72
ARG A  91
ASN A 174
 None
 0.77A 3qxvD-4yfaA:
undetectable		 3qxvD-4yfaA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yfa PROTEIN RELATED TO
PENICILLIN ACYLASE

(Acidovorax sp.
MR-S7) 		PF01804
(Penicil_amidase) 		3 LEU A  78
ARG A  91
ASN A 174
 None
 0.68A 3qxvD-4yfaA:
undetectable		 3qxvD-4yfaA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zdl O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE

(Homo sapiens) 		PF05889
(SepSecS) 		3 LEU A 408
ARG A 362
ASN A 435
 None
 0.66A 3qxvD-4zdlA:
undetectable		 3qxvD-4zdlA:
13.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4zxb FAB 83-7 HEAVY CHAIN
INSULIN RECEPTOR

(Homo sapiens;
Mus musculus) 		PF00041
(fn3)
PF00757
(Furin-like)
PF01030
(Recep_L_domain)
PF07654
(C1-set)
PF07686
(V-set) 		3 LEU A   4
ARG E 236
ASN A  73
 None
 0.51A 3qxvD-4zxbA:
19.1		 3qxvD-4zxbA:
48.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aar POTASSIUM CHANNEL
AKT1

(Arabidopsis
thaliana) 		PF12796
(Ank_2) 		3 LEU A 534
ARG A 552
ASN A 545
 None
 0.77A 3qxvD-5aarA:
undetectable		 3qxvD-5aarA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aul PHOSPHATIDYLINOSITOL
3-KINASE REGULATORY
SUBUNIT ALPHA

(Homo sapiens) 		PF00017
(SH2) 		3 LEU A 710
ARG A 649
ASN A 673
 None
 0.78A 3qxvD-5aulA:
undetectable		 3qxvD-5aulA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE

(Acidovorax sp.
MR-S7) 		PF01804
(Penicil_amidase) 		3 LEU A  72
ARG A  91
ASN A 174
 None
 0.77A 3qxvD-5c9iA:
undetectable		 3qxvD-5c9iA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE

(Acidovorax sp.
MR-S7) 		PF01804
(Penicil_amidase) 		3 LEU A  78
ARG A  91
ASN A 174
 None
 0.66A 3qxvD-5c9iA:
undetectable		 3qxvD-5c9iA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e4i CONTACTIN-5

(Mus musculus) 		PF07679
(I-set)
PF13927
(Ig_3) 		3 LEU A 288
ARG A 244
ASN A 326
 None
 0.74A 3qxvD-5e4iA:
8.1		 3qxvD-5e4iA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5evl BETA-LACTAMASE

(Chromobacterium
violaceum) 		PF00144
(Beta-lactamase) 		3 LEU A 364
ARG A 351
ASN A 314
 None
 0.78A 3qxvD-5evlA:
undetectable		 3qxvD-5evlA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f7u CYCLOALTERNAN-FORMIN
G ENZYME

(Listeria
monocytogenes) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF16338
(DUF4968)
PF16990
(CBM_35) 		3 LEU A 534
ARG A 614
ASN A 588
 None
GLC  A1116 (-2.8A)
None
 0.74A 3qxvD-5f7uA:
3.3		 3qxvD-5f7uA:
7.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jly THIOREDOXIN
PEROXIDASE-1

(Schistosoma
japonicum) 		PF00578
(AhpC-TSA)
PF10417
(1-cysPrx_C) 		3 LEU A  27
ARG A 136
ASN A  66
 None
 0.78A 3qxvD-5jlyA:
undetectable		 3qxvD-5jlyA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kyu PROTEIN TRANSPORT
PROTEIN SEC24D

(Homo sapiens) 		PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS) 		3 LEU B 926
ARG B 871
ASN B 788
 None
 0.73A 3qxvD-5kyuB:
1.8		 3qxvD-5kyuB:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mpd 26S PROTEASOME
REGULATORY SUBUNIT
RPN7

(Saccharomyces
cerevisiae) 		PF01399
(PCI)
PF10602
(RPN7) 		3 LEU R 154
ARG R 209
ASN R  23
 None
 0.73A 3qxvD-5mpdR:
undetectable		 3qxvD-5mpdR:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n1q METHYL-COENZYME M
REDUCTASE III FROM
METHANOTHERMOCOCCUS
THERMOLITHOTROPHICUS
SUBUNIT GAMMA

(Methanothermococcus
thermolithotrophicus) 		PF02240
(MCR_gamma) 		3 LEU C  31
ARG C 151
ASN C  17
 None
 0.77A 3qxvD-5n1qC:
undetectable		 3qxvD-5n1qC:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III

(Bacteroides
thetaiotaomicron) 		no annotation 3 LEU A 157
ARG A  81
ASN A  90
 None
 0.68A 3qxvD-5na7A:
undetectable		 3qxvD-5na7A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u56 MACROPHAGE GROWTH
LOCUS A
STRINGENT STARVATION
PROTEIN A

(Francisella
tularensis) 		PF00043
(GST_C)
PF13417
(GST_N_3) 		3 LEU C 150
ARG A  89
ASN C  63
 None
 0.76A 3qxvD-5u56C:
undetectable		 3qxvD-5u56C:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3j TOLL-LIKE RECEPTOR 9

(Equus caballus) 		no annotation 3 LEU A 600
ARG A 659
ASN A 608
 None
 0.69A 3qxvD-5y3jA:
undetectable		 3qxvD-5y3jA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6axf RAS GUANYL-RELEASING
PROTEIN 2

(Homo sapiens) 		no annotation 3 LEU A 361
ARG A 351
ASN A 239
 None
 0.77A 3qxvD-6axfA:
undetectable		 3qxvD-6axfA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b23 MAJOR HEAD PROTEIN

(Staphylococcus
virus 80alpha) 		no annotation 3 LEU A  39
ARG A 104
ASN A 100
 None
 0.75A 3qxvD-6b23A:
undetectable		 3qxvD-6b23A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dfu TRYPTOPHAN--TRNA
LIGASE

(Haemophilus
influenzae) 		no annotation 3 LEU A  64
ARG A 307
ASN A  75
 None
 0.77A 3qxvD-6dfuA:
undetectable		 3qxvD-6dfuA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eon BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		no annotation 3 LEU A 156
ARG A 142
ASN A  81
 None
 0.72A 3qxvD-6eonA:
2.2		 3qxvD-6eonA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fuy VINCULIN

(Homo sapiens) 		no annotation 3 LEU A 609
ARG A 684
ASN A 229
 None
 0.62A 3qxvD-6fuyA:
undetectable		 3qxvD-6fuyA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g96 ACETYLTRANSFERASE

(Salmonella
enterica) 		no annotation 3 LEU B 110
ARG B  57
ASN B  28
 None
 0.73A 3qxvD-6g96B:
undetectable		 3qxvD-6g96B:
19.38