SIMILAR PATTERNS OF AMINO ACIDS FOR 3QXV_D_MTXD2000_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1g6v | ANTIBODY HEAVY CHAIN (Camelusdromedarius) |
PF07686(V-set) | 5 | VAL K 802ALA K 824MET K 834VAL K 877TYR K 915 | None | 0.69A | 3qxvD-1g6vK:20.1 | 3qxvD-1g6vK:69.53 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1i3u | ANTIBODY VHH LAMADOMAIN (Lama glama) |
PF07686(V-set) | 5 | ALA A 24ARG A 77VAL A 84ALA A 103TYR A 118 | NoneNoneNoneNoneCGN A 1 ( 4.0A) | 0.84A | 3qxvD-1i3uA:20.8 | 3qxvD-1i3uA:59.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1kxt | IMMUNOGLOBULIN VHHFRAGMENT (Camelusdromedarius) |
PF07686(V-set) | 5 | VAL B 2ALA B 24MET B 34ALA B 94TYR B 102 | None | 0.98A | 3qxvD-1kxtB:19.2 | 3qxvD-1kxtB:68.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1pz5 | HEAVY CHAIN OF FAB(SYA/J6) (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 5 | VAL B 2ALA B 24MET B 34ARG B 71VAL B 78 | None | 0.79A | 3qxvD-1pz5B:19.9 | 3qxvD-1pz5B:51.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t3q | QUINOLINE2-OXIDOREDUCTASELARGE SUBUNIT (Pseudomonasputida) |
PF01315(Ald_Xan_dh_C)PF02738(Ald_Xan_dh_C2) | 5 | ALA B 314ARG B 416SER B 354ARG B 188VAL B 186 | None | 0.93A | 3qxvD-1t3qB:undetectable | 3qxvD-1t3qB:10.68 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1t66 | IMMUNOGLOBULIN HEAVYCHAIN (Mus musculus) |
no annotation | 5 | ALA H 24MET H 34ARG H 74VAL H 81TYR H 107 | None | 0.79A | 3qxvD-1t66H:19.3 | 3qxvD-1t66H:31.43 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1t66 | IMMUNOGLOBULIN HEAVYCHAIN (Mus musculus) |
no annotation | 5 | VAL H 2MET H 34ARG H 74VAL H 81TYR H 107 | None | 0.76A | 3qxvD-1t66H:19.3 | 3qxvD-1t66H:31.43 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2x6m | HEAVY CHAIN VARIABLEDOMAIN FROMDROMEDARY (Camelusdromedarius) |
PF07686(V-set) | 5 | ALA A 24MET A 34VAL A 80ALA A 99TYR A 115 | None | 0.66A | 3qxvD-2x6mA:21.1 | 3qxvD-2x6mA:70.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2xa3 | LLAMA HEAVY CHAINANTIBODY D7 (Lama glama) |
PF07686(V-set) | 5 | SER A 29MET A 34VAL A 78ALA A 94TYR A 102 | SO4 A1114 (-2.7A)NoneNoneNoneNone | 0.68A | 3qxvD-2xa3A:20.8 | 3qxvD-2xa3A:69.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3g9a | MINIMIZER (Camelusdromedarius) |
PF07686(V-set) | 7 | VAL B 2ALA B 24MET B 34ARG B 71VAL B 78ALA B 94TYR B 102 | None | 0.83A | 3qxvD-3g9aB:19.5 | 3qxvD-3g9aB:64.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3if1 | IMMUNOGLOBULIN HEAVYCHAIN (IGG2A) (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 5 | VAL B 2ALA B 24MET B 34ARG B 71TYR B 102 | None | 0.70A | 3qxvD-3if1B:19.5 | 3qxvD-3if1B:32.21 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3k7u | ANTIBODY (Lama glama) |
PF07686(V-set) | 5 | MET A 34ARG A 72VAL A 79ALA A 98TYR A 111 | None | 0.39A | 3qxvD-3k7uA:21.9 | 3qxvD-3k7uA:73.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ln9 | IMMUNOGLOBULIN HEAVYCHAIN ANTIBODYVARIABLE DOMAIN B10 (Camelidae) |
PF07686(V-set) | 5 | ALA A 24ARG A 72VAL A 79ALA A 98TYR A 113 | NoneNoneNoneNoneGOL A 137 (-4.8A) | 0.77A | 3qxvD-3ln9A:19.2 | 3qxvD-3ln9A:67.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3qxu | ANTI-METHOTREXATECDR1-3 GRAFT (Lama glama) |
PF07686(V-set) | 6 | SER A 30TRP A 34MET A 36VAL A 81ALA A 100TYR A 120 | None | 1.48A | 3qxvD-3qxuA:24.0 | 3qxvD-3qxuA:96.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3qxu | ANTI-METHOTREXATECDR1-3 GRAFT (Lama glama) |
PF07686(V-set) | 7 | SER A 31TRP A 34MET A 36ARG A 74VAL A 81ALA A 100TYR A 120 | None | 1.40A | 3qxvD-3qxuA:24.0 | 3qxvD-3qxuA:96.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3qxu | ANTI-METHOTREXATECDR1-3 GRAFT (Lama glama) |
PF07686(V-set) | 7 | VAL A 4ALA A 26SER A 30MET A 36VAL A 81ALA A 100TYR A 120 | None | 0.90A | 3qxvD-3qxuA:24.0 | 3qxvD-3qxuA:96.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3qxu | ANTI-METHOTREXATECDR1-3 GRAFT (Lama glama) |
PF07686(V-set) | 8 | VAL A 4ALA A 26SER A 31MET A 36ARG A 74VAL A 81ALA A 100TYR A 120 | None | 0.88A | 3qxvD-3qxuA:24.0 | 3qxvD-3qxuA:96.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3qyc | VH DOMAIN OF IGGMOLECULE (Homo sapiens) |
PF07686(V-set) | 5 | VAL A 4ALA A 26MET A 36ARG A 74VAL A 81 | None | 0.69A | 3qxvD-3qycA:19.8 | 3qxvD-3qycA:61.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3r0m | LLAMA VHH A12 (Lama glama) |
PF07686(V-set) | 5 | ALA A 24SER A 29MET A 34VAL A 78ALA A 94 | NoneSO4 A 131 (-2.7A)NoneNoneNone | 0.94A | 3qxvD-3r0mA:21.2 | 3qxvD-3r0mA:70.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3stb | SINGLE DOMAINANTIBODY VHH (Lama glama) |
PF07686(V-set) | 5 | ALA A 26MET A 36ARG A 73VAL A 80ALA A 99 | None | 0.65A | 3qxvD-3stbA:22.0 | 3qxvD-3stbA:70.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3tpk | IMMUNOGLOBULIN HEAVYCHAIN ANTIBODYVARIABLE DOMAIN KW1 (Camelidae) |
PF07686(V-set) | 5 | VAL A 2ALA A 24VAL A 79ALA A 98TYR A 110 | NoneBEN A 133 (-3.6A)BEN A 133 (-4.6A)BEN A 133 ( 4.2A)None | 0.92A | 3qxvD-3tpkA:20.3 | 3qxvD-3tpkA:64.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4aq1 | NBKB6 (Lama glama) |
PF07686(V-set) | 5 | MET B 34ARG B 72VAL B 79ALA B 98TYR B 113 | None | 0.97A | 3qxvD-4aq1B:21.8 | 3qxvD-4aq1B:74.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4b41 | ANTIBODY G7 (Lama glama) |
PF07686(V-set) | 5 | VAL A 2ALA A 24MET A 34VAL A 78ALA A 97 | None | 0.90A | 3qxvD-4b41A:18.6 | 3qxvD-4b41A:72.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4dka | SINGLE DOMAINANTIBODY VHH (Lama glama) |
PF07686(V-set) | 7 | VAL A 2ALA A 24MET A 34ARG A 72VAL A 79ALA A 98TYR A 116 | None | 0.81A | 3qxvD-4dkaA:22.0 | 3qxvD-4dkaA:73.23 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4eig | CA1698 CAMELANTIBODY FRAGMENT (Lama glama) |
PF07686(V-set) | 6 | ALA B 24MET B 34ARG B 71VAL B 78ALA B 97TYR B 106 | None | 0.72A | 3qxvD-4eigB:20.2 | 3qxvD-4eigB:66.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4fhb | NB179 (Lama glama) |
PF07686(V-set) | 5 | MET D 34ARG D 72VAL D 79ALA D 98TYR D 118 | None | 0.60A | 3qxvD-4fhbD:21.2 | 3qxvD-4fhbD:71.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4gft | NANOBODY (Lama glama) |
PF07686(V-set) | 5 | MET B 36ARG B 74VAL B 81ALA B 100TYR B 115 | NoneNoneNoneNonePCA B 2 ( 3.9A) | 0.38A | 3qxvD-4gftB:22.0 | 3qxvD-4gftB:66.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4hem | ANTI-BASEPLATETP901-1 LLAMA VHH 02 (Lama glama) |
PF07686(V-set) | 6 | ALA E 24MET E 34ARG E 72VAL E 79ALA E 98TYR E 112 | None | 0.64A | 3qxvD-4hemE:22.6 | 3qxvD-4hemE:73.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4hlz | FAB C179 HEAVY CHAIN (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 5 | VAL G 2MET G 34ARG G 71VAL G 78TYR G 102 | None | 0.78A | 3qxvD-4hlzG:19.0 | 3qxvD-4hlzG:53.91 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4hxa | 13D9 FAB HEAVY CHAIN (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 5 | VAL H 2MET H 34ARG H 71VAL H 78TYR H 102 | None | 0.90A | 3qxvD-4hxaH:20.6 | 3qxvD-4hxaH:53.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4krm | NANOBODY/VHH DOMAIN7D12 (Lama glama) |
PF07686(V-set) | 6 | ALA B 24MET B 34ARG B 72VAL B 79ALA B 98TYR B 113 | None | 0.71A | 3qxvD-4krmB:23.3 | 3qxvD-4krmB:70.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4krm | NANOBODY/VHH DOMAIN7D12 (Lama glama) |
PF07686(V-set) | 5 | SER B 29MET B 34VAL B 79ALA B 98TYR B 113 | None | 0.98A | 3qxvD-4krmB:23.3 | 3qxvD-4krmB:70.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4lde | CAMELID ANTIBODYFRAGMENT (Lama glama) |
PF07686(V-set) | 5 | VAL B 2ALA B 24ARG B 71VAL B 78TYR B 109 | None | 0.91A | 3qxvD-4ldeB:19.3 | 3qxvD-4ldeB:68.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4lde | CAMELID ANTIBODYFRAGMENT (Lama glama) |
PF07686(V-set) | 5 | VAL B 2MET B 34ARG B 71VAL B 78TYR B 109 | None | 0.77A | 3qxvD-4ldeB:19.3 | 3qxvD-4ldeB:68.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4lhq | CAMELID NANOBODY (Vicugna pacos) |
PF07686(V-set) | 5 | ALA B 24SER B 28MET B 34ARG B 72VAL B 79 | None | 0.83A | 3qxvD-4lhqB:21.5 | 3qxvD-4lhqB:63.28 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4mqt | NANOBODY 9-8 (Lama glama) |
PF07686(V-set) | 5 | VAL B 2ALA B 24VAL B 82ALA B 101TYR B 110 | None | 0.81A | 3qxvD-4mqtB:19.2 | 3qxvD-4mqtB:64.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4n1h | CAMELID HEAVY-CHAINANTIBODY VARIABLEFRAGMENT CAB-F11N (Lama glama) |
PF07686(V-set) | 5 | ALA B 24MET B 34ARG B 72VAL B 79ALA B 98 | None | 0.81A | 3qxvD-4n1hB:21.3 | 3qxvD-4n1hB:68.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4nc1 | A20.1 VHH (Lama glama) |
PF07686(V-set) | 7 | VAL C 9ALA C 31MET C 41ARG C 79VAL C 86ALA C 105TYR C 119 | None | 0.90A | 3qxvD-4nc1C:22.0 | 3qxvD-4nc1C:70.23 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4nc2 | B39 VHH (Lama glama) |
PF07686(V-set) | 5 | ALA B 24MET B 34ARG B 71ALA B 97TYR B 111 | None | 0.75A | 3qxvD-4nc2B:22.8 | 3qxvD-4nc2B:70.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4nc2 | B39 VHH (Lama glama) |
PF07686(V-set) | 5 | VAL B 2MET B 34ARG B 71ALA B 97TYR B 111 | None | 0.63A | 3qxvD-4nc2B:22.8 | 3qxvD-4nc2B:70.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4p2c | NANOBODY 1,ANTI-F4+ETECBACTERIA VHHVARIABLE REGION (Lama glama) |
PF07686(V-set) | 6 | VAL G 2MET G 34ARG G 71VAL G 78ALA G 97TYR G 111 | None | 0.62A | 3qxvD-4p2cG:19.1 | 3qxvD-4p2cG:70.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4p49 | ANTIBODY SCFV B8 (Gallus gallus) |
PF07686(V-set) | 5 | VAL A 122ALA A 144MET A 154ARG A 193VAL A 200 | None | 0.91A | 3qxvD-4p49A:21.7 | 3qxvD-4p49A:51.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4pb0 | AB53 HEAVY CHAIN (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 5 | VAL H 2ALA H 24MET H 34ARG H 71VAL H 78 | CL H 303 (-4.4A)NoneNoneNoneNone | 0.93A | 3qxvD-4pb0H:18.7 | 3qxvD-4pb0H:32.26 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4qlr | LLAMA NANOBODY N02VH DOMAIN (Lama glama) |
PF07686(V-set) | 5 | ALA A 24ARG A 72VAL A 79ALA A 98TYR A 113 | None | 0.76A | 3qxvD-4qlrA:22.4 | 3qxvD-4qlrA:69.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4qo1 | NB139 NANOBODYAGAINST THEDNA-BINDING DOMAINOF P53 (Lama glama) |
PF07686(V-set) | 6 | ALA A 25MET A 35ARG A 73VAL A 80ALA A 99TYR A 113 | None | 0.57A | 3qxvD-4qo1A:21.2 | 3qxvD-4qo1A:62.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4tvs | VHH DOMAIN BS-1 (Vicugna pacos) |
PF05609(LAP1C) | 5 | ALA a 25ARG a 73VAL a 80ALA a 99TYR a 117 | None | 0.79A | 3qxvD-4tvsa:22.1 | 3qxvD-4tvsa:72.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4w6y | NANOBODY NBFEDF9 (Lama glama) |
PF07686(V-set) | 6 | VAL B 2ALA B 24MET B 34VAL B 79ALA B 98TYR B 118 | None | 0.92A | 3qxvD-4w6yB:21.0 | 3qxvD-4w6yB:69.47 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4weu | ANTI-F4+ETECBACTERIA VHHVARIABLE REGION (Lama glama) |
PF07686(V-set) | 6 | VAL D 802ALA D 824MET D 834ARG D 872ALA D 898TYR D 910 | None | 0.68A | 3qxvD-4weuD:22.3 | 3qxvD-4weuD:72.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4x8j | 12F4 FAB HEAVY CHAIN (Mus musculus) |
no annotation | 5 | VAL H 2MET H 34ARG H 74VAL H 81TYR H 104 | NoneNoneNoneNone2PE H 302 ( 4.6A) | 0.67A | 3qxvD-4x8jH:15.5 | 3qxvD-4x8jH:33.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4xt1 | NANOBODY 7 (Vicugna pacos) |
PF07686(V-set) | 6 | VAL C 2ALA C 24MET C 34VAL C 78ALA C 97TYR C 107 | None | 0.87A | 3qxvD-4xt1C:19.0 | 3qxvD-4xt1C:68.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a2k | IG LAMBDA-1 CHAIN VREGION S43 (Mus musculus) |
PF07686(V-set) | 6 | VAL H 2ALA H 24MET H 34ARG H 71VAL H 78TYR H 102 | None | 0.79A | 3qxvD-5a2kH:19.8 | 3qxvD-5a2kH:29.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5aum | HEAVY CHAIN OF FABFRAGMENT (Rattus) |
no annotation | 5 | ALA H 24MET H 34ARG H 71VAL H 78ALA H 94 | None | 0.67A | 3qxvD-5aumH:19.7 | 3qxvD-5aumH:38.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5aum | HEAVY CHAIN OF FABFRAGMENT (Rattus) |
no annotation | 5 | VAL H 2MET H 34ARG H 71VAL H 78ALA H 94 | None | 0.58A | 3qxvD-5aumH:19.7 | 3qxvD-5aumH:38.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5e1h | F8(JOB10) VHHANTIBODY (Vicugna pacos) |
PF07686(V-set) | 5 | VAL B 2ALA B 24MET B 34ARG B 72VAL B 79 | None | 0.83A | 3qxvD-5e1hB:20.3 | 3qxvD-5e1hB:68.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5e7f | NANOBODY L06 (Camelusdromedarius) |
PF07686(V-set) | 5 | VAL A 4MET A 36ARG A 73VAL A 80ALA A 99 | None | 0.72A | 3qxvD-5e7fA:18.4 | 3qxvD-5e7fA:66.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5fwo | NANOBODY (Lama glama) |
PF07686(V-set) | 6 | VAL A 2ALA A 24MET A 34ARG A 71VAL A 78TYR A 102 | None | 0.87A | 3qxvD-5fwoA:21.5 | 3qxvD-5fwoA:68.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5fwo | NANOBODY (Lama glama) |
PF07686(V-set) | 6 | VAL A 2MET A 34ARG A 71VAL A 78ALA A 94TYR A 102 | None | 0.62A | 3qxvD-5fwoA:21.5 | 3qxvD-5fwoA:68.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gxb | NANOBODY (Vicugna pacos) |
PF07686(V-set) | 6 | VAL B 2ALA B 24MET B 34VAL B 79ALA B 98TYR B 118 | None | 1.09A | 3qxvD-5gxbB:20.9 | 3qxvD-5gxbB:68.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hm1 | LAMA VHH ANTIBODY2E7 (Lama glama) |
PF07686(V-set) | 5 | VAL A 2ALA A 24VAL A 78ALA A 94TYR A 102 | None | 0.69A | 3qxvD-5hm1A:18.7 | 3qxvD-5hm1A:68.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hvf | VHH-I83 (Vicugna pacos) |
PF07686(V-set) | 6 | VAL B 2ALA B 24ARG B 70VAL B 77ALA B 96TYR B 108 | None | 0.86A | 3qxvD-5hvfB:18.5 | 3qxvD-5hvfB:69.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hvf | VHH-I83 (Vicugna pacos) |
PF07686(V-set) | 6 | VAL B 2ALA B 24MET B 34VAL B 77ALA B 96TYR B 108 | None | 0.95A | 3qxvD-5hvfB:18.5 | 3qxvD-5hvfB:69.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5iml | NANOBODY (Camelidae) |
PF07686(V-set) | 6 | ALA B 23MET B 33ARG B 71VAL B 78ALA B 97TYR B 113 | None | 0.75A | 3qxvD-5imlB:23.6 | 3qxvD-5imlB:75.40 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5j1s | VHH DOMAIN BS-2 (Vicugna pacos) |
PF07686(V-set) | 7 | VAL C 3ALA C 25MET C 35ARG C 72VAL C 79ALA C 98TYR C 112 | None | 0.88A | 3qxvD-5j1sC:19.5 | 3qxvD-5j1sC:66.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5j56 | VHH SINGLE CHAINANTIBODY V1C7 (Vicugna pacos) |
PF07686(V-set) | 6 | VAL B 2ALA B 24ARG B 76VAL B 83ALA B 102TYR B 117 | None | 0.91A | 3qxvD-5j56B:20.7 | 3qxvD-5j56B:67.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ja9 | NANOBODY 6 (Lama glama) |
PF07686(V-set) | 5 | VAL A 3ALA A 25MET A 35ARG A 73ALA A 99 | None | 0.93A | 3qxvD-5ja9A:20.2 | 3qxvD-5ja9A:68.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5jqh | NANOBODY60, NB60 (Lama glama) |
no annotation | 5 | VAL D 2MET D 34ARG D 71VAL D 78ALA D 97 | None | 0.95A | 3qxvD-5jqhD:19.2 | 3qxvD-5jqhD:70.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5kel | C2G4 VARIABLE FABDOMAIN HEAVY CHAIN (Homo sapiens) |
PF07686(V-set) | 6 | VAL H 2ALA H 24MET H 34ARG H 71VAL H 78TYR H 102 | None | 0.99A | 3qxvD-5kelH:17.1 | 3qxvD-5kelH:51.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5lhq | CAMELID-DERIVEDANTIBODY FRAGMENTNB7 (Vicugna pacos) |
PF07686(V-set) | 6 | VAL B 2ALA B 24ARG B 72VAL B 79ALA B 98TYR B 122 | None | 0.62A | 3qxvD-5lhqB:21.6 | 3qxvD-5lhqB:64.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5lmj | NANOBODY (Lama glama) |
PF07686(V-set) | 6 | ALA A 24MET A 34ARG A 71VAL A 78ALA A 94TYR A 102 | None | 0.95A | 3qxvD-5lmjA:20.2 | 3qxvD-5lmjA:73.23 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5lmj | NANOBODY (Lama glama) |
PF07686(V-set) | 6 | VAL A 2ALA A 24ARG A 71VAL A 78ALA A 94TYR A 102 | None | 0.95A | 3qxvD-5lmjA:20.2 | 3qxvD-5lmjA:73.23 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5lwf | CAMELID HEAVY-CHAINANTIBODY VARIABLEFRAGMENT CAB-G10S (Lama glama) |
no annotation | 6 | ALA C 27MET C 37ARG C 75VAL C 82ALA C 101TYR C 117 | NoneNoneNoneNoneNoneACT C 202 (-4.4A) | 0.59A | 3qxvD-5lwfC:21.3 | 3qxvD-5lwfC:68.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5lwf | CAMELID HEAVY-CHAINANTIBODY VARIABLEFRAGMENT CAB-G10S (Lama glama) |
no annotation | 5 | VAL C 5ARG C 75VAL C 82ALA C 101TYR C 117 | NoneNoneNoneNoneACT C 202 (-4.4A) | 0.86A | 3qxvD-5lwfC:21.3 | 3qxvD-5lwfC:68.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5m13 | SYNTHETIC NANOBODYL2_C06 (A-MBP#2) (syntheticconstruct) |
no annotation | 5 | VAL B 2ALA B 24VAL B 79ALA B 98TYR B 114 | None | 0.93A | 3qxvD-5m13B:21.8 | 3qxvD-5m13B:63.64 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5mwn | LLAMA NANOBODYRAISED AGAINST TSSK,NBK27 (Lama glama) |
PF07686(V-set) | 5 | VAL N 2ALA N 24ARG N 71VAL N 78ALA N 97 | None | 0.94A | 3qxvD-5mwnN:18.3 | 3qxvD-5mwnN:67.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5mwn | LLAMA NANOBODYRAISED AGAINST TSSK,NBK27 (Lama glama) |
PF07686(V-set) | 5 | VAL N 2ALA N 24MET N 34VAL N 78ALA N 97 | None | 0.95A | 3qxvD-5mwnN:18.3 | 3qxvD-5mwnN:67.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5o02 | NANOBODY (VHH)NANO-4 (Vicugna pacos) |
PF07686(V-set) | 5 | VAL C 2MET C 34ARG C 72ALA C 98TYR C 113 | None | 0.66A | 3qxvD-5o02C:21.3 | 3qxvD-5o02C:68.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5o03 | NANOBODY (VHH)NANO-32 (Norwalk virus) |
PF07686(V-set) | 5 | ALA C 24ARG C 72VAL C 79ALA C 98TYR C 124 | None | 0.88A | 3qxvD-5o03C:20.3 | 3qxvD-5o03C:63.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5o04 | NANOBODY (VHH)NANO-26 (Vicugna pacos) |
PF07686(V-set) | 5 | VAL E 2ALA E 24ARG E 71VAL E 78TYR E 104 | None | 0.83A | 3qxvD-5o04E:18.7 | 3qxvD-5o04E:65.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5o05 | NANOBODY (VHH)NANO-42 (Vicugna pacos) |
PF07686(V-set) | 5 | VAL C 2ALA C 24SER C 29VAL C 78TYR C 109 | None | 0.90A | 3qxvD-5o05C:17.1 | 3qxvD-5o05C:67.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5o8f | NANOBODY NB25 (Lama glama) |
no annotation | 5 | MET L 34ARG L 72VAL L 79ALA L 98TYR L 114 | None | 0.62A | 3qxvD-5o8fL:21.4 | 3qxvD-5o8fL:68.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5uk4 | ANTI-VESICULARSTOMATITIS VIRUS NVHH (Vicugna pacos) |
no annotation | 6 | VAL p 2MET p 34ARG p 72VAL p 79ALA p 98TYR p 114 | None | 0.76A | 3qxvD-5uk4p:21.4 | 3qxvD-5uk4p:71.43 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ukb | ANTI-VESICULARSTOMATITIS VIRUS NVHH (Vicugna pacos) |
no annotation | 5 | ALA d 24ARG d 72VAL d 79ALA d 98TYR d 113 | None | 0.74A | 3qxvD-5ukbd:22.3 | 3qxvD-5ukbd:70.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5vgj | VRC38.01 FAB HEAVYCHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 5 | VAL H 2ALA H 24MET H 34ARG H 71VAL H 78 | None | 0.69A | 3qxvD-5vgjH:19.1 | 3qxvD-5vgjH:36.45 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5vxj | SINGLE-DOMAINANTIBODY JMK-E3 (Vicugna pacos) |
no annotation | 6 | VAL B 2MET B 34ARG B 72VAL B 79ALA B 98TYR B 108 | None | 0.78A | 3qxvD-5vxjB:19.2 | 3qxvD-5vxjB:63.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5vxl | SINGLE-DOMAINANTIBODY JPS-G3 (Vicugna pacos) |
no annotation | 5 | ALA B 24MET B 34ARG B 73ALA B 99TYR B 106 | None | 0.69A | 3qxvD-5vxlB:20.2 | 3qxvD-5vxlB:66.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5vxl | SINGLE-DOMAINANTIBODY JPS-G3 (Vicugna pacos) |
no annotation | 5 | MET B 34ARG B 73VAL B 80ALA B 99TYR B 106 | None | 0.60A | 3qxvD-5vxlB:20.2 | 3qxvD-5vxlB:66.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wb1 | ENVELOPE PROTEINUS28, NANOBODY 7FUSION PROTEIN (Humanbetaherpesvirus5;Lama glama) |
no annotation | 6 | VAL A1002ALA A1024MET A1034VAL A1078ALA A1097TYR A1107 | None | 0.93A | 3qxvD-5wb1A:18.1 | 3qxvD-5wb1A:15.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5wb2 | NANOBODY B1 (syntheticconstruct) |
no annotation | 5 | ALA D 24ARG D 72VAL D 79ALA D 98TYR D 118 | None | 0.91A | 3qxvD-5wb2D:18.8 | 3qxvD-5wb2D:68.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5x0t | 6H8 FAB FRAGMENTHEAVY CHAIN (Mus musculus) |
no annotation | 5 | ALA A 43MET A 53ARG A 93VAL A 100TYR A 124 | None | 0.76A | 3qxvD-5x0tA:19.7 | 3qxvD-5x0tA:31.40 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5x0t | 6H8 FAB FRAGMENTHEAVY CHAIN (Mus musculus) |
no annotation | 5 | VAL A 21MET A 53ARG A 93VAL A 100TYR A 124 | None | 0.73A | 3qxvD-5x0tA:19.7 | 3qxvD-5x0tA:31.40 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5y9f | HEAVY CHAIN OF FABFRAGMENT OF ANTIBODY28F10 (Mus musculus) |
no annotation | 5 | VAL L 2ALA L 24MET L 34ARG L 72TYR L 112 | None | 0.96A | 3qxvD-5y9fL:20.0 | 3qxvD-5y9fL:57.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dbe | NANOBODY VHH R303 (Lama glama) |
no annotation | 6 | SER A 30MET A 34ARG A 72VAL A 79ALA A 98TYR A 107 | None | 1.22A | 3qxvD-6dbeA:20.4 | 3qxvD-6dbeA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dbe | NANOBODY VHH R303 (Lama glama) |
no annotation | 6 | VAL A 2ALA A 24MET A 34VAL A 79ALA A 98TYR A 107 | None | 0.77A | 3qxvD-6dbeA:20.4 | 3qxvD-6dbeA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dbe | NANOBODY VHH R303 (Lama glama) |
no annotation | 6 | VAL A 2SER A 30MET A 34VAL A 79ALA A 98TYR A 107 | None | 1.03A | 3qxvD-6dbeA:20.4 | 3qxvD-6dbeA:undetectable | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6ehg | HC3NB1 (Lama glama) |
no annotation | 5 | ALA C 24MET C 34ARG C 72VAL C 79ALA C 98 | None | 0.71A | 3qxvD-6ehgC:22.4 | 3qxvD-6ehgC:57.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6ehg | HC3NB1 (Lama glama) |
no annotation | 5 | MET C 34ARG C 72VAL C 79ALA C 98TYR C 112 | None | 0.61A | 3qxvD-6ehgC:22.4 | 3qxvD-6ehgC:57.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6ehg | HC3NB1 (Lama glama) |
no annotation | 5 | VAL C 2ALA C 24MET C 34ARG C 72VAL C 79 | None | 0.91A | 3qxvD-6ehgC:22.4 | 3qxvD-6ehgC:57.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6ehg | HC3NB1 (Lama glama) |
no annotation | 5 | VAL C 2MET C 34ARG C 72VAL C 79TYR C 112 | None | 0.92A | 3qxvD-6ehgC:22.4 | 3qxvD-6ehgC:57.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6ey0 | LLAMA NANOBODY NB01 (Lama glama) |
no annotation | 5 | MET E 34ARG E 71VAL E 78ALA E 94TYR E 102 | None | 0.87A | 3qxvD-6ey0E:21.3 | 3qxvD-6ey0E:56.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gzp | NANOBODY (Lama glama) |
no annotation | 6 | VAL A 2ALA A 24MET A 34ARG A 71ALA A 94TYR A 102 | None | 0.79A | 3qxvD-6gzpA:22.1 | 3qxvD-6gzpA:undetectable |