SIMILAR PATTERNS OF AMINO ACIDS FOR 3QXV_C_MTXC2000
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1kxt | IMMUNOGLOBULIN VHHFRAGMENT (Camelusdromedarius) |
PF07686(V-set) | 6 | VAL B 2ALA B 24MET B 34ARG B 71ASN B 73ALA B 94 | None | 0.97A | 3qxvC-1kxtB:19.5 | 3qxvC-1kxtB:68.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1pz5 | HEAVY CHAIN OF FAB(SYA/J6) (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 5 | VAL B 2ALA B 24MET B 34ARG B 71VAL B 78 | None | 0.83A | 3qxvC-1pz5B:20.2 | 3qxvC-1pz5B:51.52 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2aeq | FAB HEAVY CHAIN (Mus musculus) |
PF07686(V-set) | 5 | VAL H 2MET H 34ARG H 74ASN H 76VAL H 81 | None | 0.82A | 3qxvC-2aeqH:18.2 | 3qxvC-2aeqH:33.96 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2fl5 | IMMUNOGLOBULIN IGG1HEAVY CHAIN (Homo sapiens) |
no annotation | 5 | VAL H 2ALA H 24MET H 34ARG H 71ASN H 73 | None | 0.77A | 3qxvC-2fl5H:20.8 | 3qxvC-2fl5H:35.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jgv | TAGATOSE-6-PHOSPHATEKINASE (Staphylococcusaureus) |
PF00294(PfkB) | 6 | VAL A 239ALA A 230ARG A 238SER A 222VAL A 181ALA A 277 | None | 1.08A | 3qxvC-2jgvA:undetectable | 3qxvC-2jgvA:16.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2uzi | ANTI-RAS FV HEAVYCHAIN (Homo sapiens) |
PF07686(V-set) | 5 | VAL H 2ALA H 24MET H 34ARG H 72ASN H 74 | None | 0.79A | 3qxvC-2uziH:21.4 | 3qxvC-2uziH:60.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2xa3 | LLAMA HEAVY CHAINANTIBODY D7 (Lama glama) |
PF07686(V-set) | 5 | SER A 29MET A 34ASN A 73VAL A 78ALA A 94 | SO4 A1114 (-2.7A)NoneNoneNoneNone | 0.80A | 3qxvC-2xa3A:21.2 | 3qxvC-2xa3A:69.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3g9a | MINIMIZER (Camelusdromedarius) |
PF07686(V-set) | 5 | ALA B 24MET B 34ARG B 71VAL B 78ALA B 94 | None | 0.71A | 3qxvC-3g9aB:20.0 | 3qxvC-3g9aB:64.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3k7u | ANTIBODY (Lama glama) |
PF07686(V-set) | 5 | MET A 34ARG A 72ASN A 74VAL A 79ALA A 98 | None | 0.28A | 3qxvC-3k7uA:22.1 | 3qxvC-3k7uA:73.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ln9 | IMMUNOGLOBULIN HEAVYCHAIN ANTIBODYVARIABLE DOMAIN B10 (Camelidae) |
PF07686(V-set) | 6 | VAL A 2ALA A 24ARG A 72ASN A 74VAL A 79ALA A 98 | None | 0.85A | 3qxvC-3ln9A:19.7 | 3qxvC-3ln9A:67.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3piq | HUMAN MONOCLONALANTIBODY 2909 FABHEAVY CHAIN (Homo sapiens) |
no annotation | 5 | VAL H 2ALA H 24MET H 34ARG H 71ASN H 73 | None | 0.80A | 3qxvC-3piqH:19.6 | 3qxvC-3piqH:56.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3qxu | ANTI-METHOTREXATECDR1-3 GRAFT (Lama glama) |
PF07686(V-set) | 7 | VAL A 4ALA A 26SER A 30MET A 36ARG A 74VAL A 81ALA A 100 | None | 0.89A | 3qxvC-3qxuA:24.5 | 3qxvC-3qxuA:96.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3qyc | VH DOMAIN OF IGGMOLECULE (Homo sapiens) |
PF07686(V-set) | 5 | ALA A 26MET A 36ARG A 74ASN A 76VAL A 81 | None | 0.73A | 3qxvC-3qycA:20.1 | 3qxvC-3qycA:61.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3qyc | VH DOMAIN OF IGGMOLECULE (Homo sapiens) |
PF07686(V-set) | 5 | VAL A 4ALA A 26MET A 36ARG A 74VAL A 81 | None | 0.83A | 3qxvC-3qycA:20.1 | 3qxvC-3qycA:61.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3r0m | LLAMA VHH A12 (Lama glama) |
PF07686(V-set) | 6 | ALA A 24SER A 29MET A 34ASN A 73VAL A 78ALA A 94 | NoneSO4 A 131 (-2.7A)NoneNoneNoneNone | 1.12A | 3qxvC-3r0mA:21.2 | 3qxvC-3r0mA:70.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3stb | SINGLE DOMAINANTIBODY VHH (Lama glama) |
PF07686(V-set) | 6 | ALA A 26MET A 36ARG A 73ASN A 75VAL A 80ALA A 99 | None | 0.71A | 3qxvC-3stbA:22.5 | 3qxvC-3stbA:70.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4dgy | HCV1 HEAVY CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 5 | VAL H 2ALA H 24MET H 34ARG H 71ASN H 73 | GOL H 302 (-4.1A)NoneNoneNoneNone | 0.80A | 3qxvC-4dgyH:20.6 | 3qxvC-4dgyH:37.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4dka | SINGLE DOMAINANTIBODY VHH (Lama glama) |
PF07686(V-set) | 6 | ALA A 24MET A 34ARG A 72ASN A 74VAL A 79ALA A 98 | None | 0.78A | 3qxvC-4dkaA:22.3 | 3qxvC-4dkaA:73.23 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4eig | CA1698 CAMELANTIBODY FRAGMENT (Lama glama) |
PF07686(V-set) | 6 | ALA B 24MET B 34ARG B 71ASN B 73VAL B 78ALA B 97 | None | 0.75A | 3qxvC-4eigB:20.5 | 3qxvC-4eigB:66.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ej1 | NB113 CAMELIDANTIBODY FRAGMENT (Lama glama) |
PF07686(V-set) | 5 | ALA C 24MET C 34ASN C 74VAL C 79ALA C 98 | None | 0.70A | 3qxvC-4ej1C:21.7 | 3qxvC-4ej1C:74.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ej1 | NB113 CAMELIDANTIBODY FRAGMENT (Lama glama) |
PF07686(V-set) | 5 | MET C 34ARG C 72ASN C 74VAL C 79ALA C 98 | None | 0.38A | 3qxvC-4ej1C:21.7 | 3qxvC-4ej1C:74.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4fhb | NB179 (Lama glama) |
PF07686(V-set) | 5 | MET D 34ARG D 72ASN D 74VAL D 79ALA D 98 | None | 0.50A | 3qxvC-4fhbD:21.4 | 3qxvC-4fhbD:71.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4fql | MONOCLONAL ANTIBODYCR8033 HEAVY CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 5 | VAL H 2ALA H 24MET H 34ARG H 71ASN H 73 | None | 0.75A | 3qxvC-4fqlH:21.7 | 3qxvC-4fqlH:59.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4gft | NANOBODY (Lama glama) |
PF07686(V-set) | 5 | MET B 36ARG B 74ASN B 76VAL B 81ALA B 100 | None | 0.26A | 3qxvC-4gftB:22.7 | 3qxvC-4gftB:66.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4glr | ANTI-PTAU HEAVYCHAIN (Gallus gallus) |
PF07654(C1-set)PF07686(V-set) | 5 | VAL H 2MET H 34ARG H 71ASN H 73VAL H 78 | None | 0.60A | 3qxvC-4glrH:21.1 | 3qxvC-4glrH:30.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4hem | ANTI-BASEPLATETP901-1 LLAMA VHH 02 (Lama glama) |
PF07686(V-set) | 6 | ALA E 24MET E 34ARG E 72ASN E 74VAL E 79ALA E 98 | None | 0.68A | 3qxvC-4hemE:23.2 | 3qxvC-4hemE:73.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4kfz | ANTI-LMO2 VH (Homo sapiens) |
PF07686(V-set) | 6 | VAL C 2ALA C 24SER C 28MET C 34ARG C 72ASN C 74 | None | 0.90A | 3qxvC-4kfzC:20.1 | 3qxvC-4kfzC:61.83 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4krm | NANOBODY/VHH DOMAIN7D12 (Lama glama) |
PF07686(V-set) | 5 | ALA B 24MET B 34ARG B 72VAL B 79ALA B 98 | None | 0.70A | 3qxvC-4krmB:23.8 | 3qxvC-4krmB:70.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4krm | NANOBODY/VHH DOMAIN7D12 (Lama glama) |
PF07686(V-set) | 5 | MET B 34ARG B 72ASN B 74VAL B 79ALA B 98 | None | 0.34A | 3qxvC-4krmB:23.8 | 3qxvC-4krmB:70.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4lhq | CAMELID NANOBODY (Vicugna pacos) |
PF07686(V-set) | 5 | SER B 28MET B 34ARG B 72ASN B 74VAL B 79 | None | 0.64A | 3qxvC-4lhqB:22.0 | 3qxvC-4lhqB:63.28 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4n1h | CAMELID HEAVY-CHAINANTIBODY VARIABLEFRAGMENT CAB-F11N (Lama glama) |
PF07686(V-set) | 5 | ALA B 24MET B 34ASN B 74VAL B 79ALA B 98 | None | 0.69A | 3qxvC-4n1hB:21.6 | 3qxvC-4n1hB:68.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4n1h | CAMELID HEAVY-CHAINANTIBODY VARIABLEFRAGMENT CAB-F11N (Lama glama) |
PF07686(V-set) | 5 | MET B 34ARG B 72ASN B 74VAL B 79ALA B 98 | None | 0.44A | 3qxvC-4n1hB:21.6 | 3qxvC-4n1hB:68.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4nc1 | A20.1 VHH (Lama glama) |
PF07686(V-set) | 7 | VAL C 9ALA C 31MET C 41ARG C 79ASN C 81VAL C 86ALA C 105 | None | 0.93A | 3qxvC-4nc1C:22.2 | 3qxvC-4nc1C:70.23 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4nc2 | B39 VHH (Lama glama) |
PF07686(V-set) | 6 | VAL B 2ALA B 24MET B 34ARG B 71ASN B 73ALA B 97 | None | 0.73A | 3qxvC-4nc2B:23.2 | 3qxvC-4nc2B:70.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ocr | CAP256-VRC26.01HEAVY CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 5 | VAL H 2MET H 34ARG H 71ASN H 73VAL H 78 | None | 0.53A | 3qxvC-4ocrH:21.7 | 3qxvC-4ocrH:54.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ouo | ANTI BLA G 1 SCFV (Gallus gallus) |
PF07686(V-set) | 6 | VAL A 116ALA A 138MET A 148ARG A 185ASN A 187VAL A 192 | None | 0.90A | 3qxvC-4ouoA:20.9 | 3qxvC-4ouoA:27.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4p2c | NANOBODY 1,ANTI-F4+ETECBACTERIA VHHVARIABLE REGION (Lama glama) |
PF07686(V-set) | 6 | VAL G 2MET G 34ARG G 71ASN G 73VAL G 78ALA G 97 | None | 0.57A | 3qxvC-4p2cG:19.1 | 3qxvC-4p2cG:70.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4p49 | ANTIBODY SCFV B8 (Gallus gallus) |
PF07686(V-set) | 6 | VAL A 122ALA A 144MET A 154ARG A 193ASN A 195VAL A 200 | None | 0.93A | 3qxvC-4p49A:22.0 | 3qxvC-4p49A:51.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4qlr | LLAMA NANOBODY N02VH DOMAIN (Lama glama) |
PF07686(V-set) | 5 | ALA A 24ARG A 72ASN A 74VAL A 79ALA A 98 | None | 0.76A | 3qxvC-4qlrA:22.5 | 3qxvC-4qlrA:69.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4qo1 | NB139 NANOBODYAGAINST THEDNA-BINDING DOMAINOF P53 (Lama glama) |
PF07686(V-set) | 6 | ALA A 25MET A 35ARG A 73ASN A 75VAL A 80ALA A 99 | None | 0.58A | 3qxvC-4qo1A:21.5 | 3qxvC-4qo1A:62.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4tvs | VHH DOMAIN BS-1 (Vicugna pacos) |
PF05609(LAP1C) | 5 | ALA a 25ARG a 73ASN a 75VAL a 80ALA a 99 | None | 0.81A | 3qxvC-4tvsa:22.6 | 3qxvC-4tvsa:72.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ut6 | BROADLY NEUTRALIZINGHUMAN ANTIBODY EDE2B7 (Homo sapiens) |
PF07686(V-set) | 5 | VAL H 2MET H 34ARG H 71ASN H 73VAL H 78 | None | 0.77A | 3qxvC-4ut6H:18.9 | 3qxvC-4ut6H:57.04 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4w6y | NANOBODY NBFEDF9 (Lama glama) |
PF07686(V-set) | 6 | VAL B 2ALA B 24MET B 34ASN B 74VAL B 79ALA B 98 | NoneNoneNoneSO4 B 201 (-4.0A)NoneNone | 0.97A | 3qxvC-4w6yB:21.3 | 3qxvC-4w6yB:69.47 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4weu | ANTI-F4+ETECBACTERIA VHHVARIABLE REGION (Lama glama) |
PF07686(V-set) | 6 | VAL D 802ALA D 824MET D 834ARG D 872ASN D 874ALA D 898 | None | 0.70A | 3qxvC-4weuD:22.4 | 3qxvC-4weuD:72.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4xt1 | NANOBODY 7 (Vicugna pacos) |
PF07686(V-set) | 6 | VAL C 2ALA C 24MET C 34ASN C 73VAL C 78ALA C 97 | None | 0.89A | 3qxvC-4xt1C:19.3 | 3qxvC-4xt1C:68.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4y5v | DIABODY 305 VHDOMAIN (Homo sapiens) |
PF07686(V-set) | 5 | VAL A 2MET A 34ARG A 72ASN A 74VAL A 79 | None | 0.53A | 3qxvC-4y5vA:21.1 | 3qxvC-4y5vA:66.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ybq | ANTIBODY FV FRAGMENTHEAVY CHAIN (Mus musculus) |
PF07686(V-set) | 5 | VAL D 3ALA D 25MET D 35ARG D 73ASN D 75 | None | 0.80A | 3qxvC-4ybqD:21.2 | 3qxvC-4ybqD:58.73 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ydv | HIV ANTIBODY 7B2HEAVY CHAIN,IGG HCHAIN (Homo sapiens) |
no annotation | 5 | VAL H 2MET H 34ARG H 71ASN H 72VAL H 75 | None | 0.66A | 3qxvC-4ydvH:19.3 | 3qxvC-4ydvH:37.56 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4yga | VHH-1B7 (Vicugna pacos) |
PF07686(V-set) | 6 | VAL B 3ALA B 25ARG B 73ASN B 75VAL B 80ALA B 99 | None | 0.72A | 3qxvC-4ygaB:20.5 | 3qxvC-4ygaB:60.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5aum | HEAVY CHAIN OF FABFRAGMENT (Rattus) |
no annotation | 6 | VAL H 2ALA H 24MET H 34ARG H 71VAL H 78ALA H 94 | None | 0.70A | 3qxvC-5aumH:20.0 | 3qxvC-5aumH:38.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5b6f | ANTI-LEUKOTRIENE C4MONOCLONAL ANTIBODYIMMUNOGLOBULINGAMMA1 HEAVY CHAIN (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 5 | VAL B 21ALA B 43MET B 53ARG B 93VAL B 100 | None | 0.80A | 3qxvC-5b6fB:19.5 | 3qxvC-5b6fB:35.07 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5bop | NANOBODY (Lama glama) |
PF07686(V-set) | 5 | MET A 34ARG A 72ASN A 74VAL A 79ALA A 98 | None | 0.53A | 3qxvC-5bopA:22.6 | 3qxvC-5bopA:69.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5drz | HIV ANTIBODY F240HEAVY CHAIN (Homo sapiens) |
no annotation | 5 | VAL H 2MET H 34ARG H 71ASN H 73VAL H 78 | None | 0.56A | 3qxvC-5drzH:18.9 | 3qxvC-5drzH:55.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dxw | PD-L1 NANOBODY (Mus musculus) |
PF07686(V-set) | 5 | VAL A 4MET A 36ARG A 74ASN A 76VAL A 81 | None | 0.74A | 3qxvC-5dxwA:20.7 | 3qxvC-5dxwA:65.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5e1h | F8(JOB10) VHHANTIBODY (Vicugna pacos) |
PF07686(V-set) | 6 | VAL B 2ALA B 24MET B 34ARG B 72ASN B 74VAL B 79 | None | 0.93A | 3qxvC-5e1hB:20.8 | 3qxvC-5e1hB:68.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5e7f | NANOBODY L06 (Camelusdromedarius) |
PF07686(V-set) | 6 | VAL A 4ALA A 26ARG A 73ASN A 75VAL A 80ALA A 99 | None | 0.88A | 3qxvC-5e7fA:18.6 | 3qxvC-5e7fA:66.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5e7f | NANOBODY L06 (Camelusdromedarius) |
PF07686(V-set) | 6 | VAL A 4MET A 36ARG A 73ASN A 75VAL A 80ALA A 99 | None | 0.64A | 3qxvC-5e7fA:18.6 | 3qxvC-5e7fA:66.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5f1k | NANOBODY MU1053 (Lama glama) |
PF07686(V-set) | 5 | MET C 34ARG C 72ASN C 74VAL C 79ALA C 98 | None | 0.46A | 3qxvC-5f1kC:22.3 | 3qxvC-5f1kC:67.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5f1o | NANOBODY MU551 (Lama glama) |
PF07686(V-set) | 5 | MET B 34ARG B 72ASN B 74VAL B 79ALA B 98 | None | 0.39A | 3qxvC-5f1oB:21.5 | 3qxvC-5f1oB:65.91 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5fhc | ANTIBODY 114 FABHEAVY CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 5 | VAL H 2ALA H 24MET H 34ARG H 71ASN H 73 | None | 0.81A | 3qxvC-5fhcH:20.4 | 3qxvC-5fhcH:37.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5fwo | NANOBODY (Lama glama) |
PF07686(V-set) | 7 | VAL A 2ALA A 24MET A 34ARG A 71ASN A 73VAL A 78ALA A 94 | None | 0.81A | 3qxvC-5fwoA:21.8 | 3qxvC-5fwoA:68.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gxb | NANOBODY (Vicugna pacos) |
PF07686(V-set) | 6 | VAL B 2ALA B 24MET B 34ASN B 74VAL B 79ALA B 98 | None | 0.89A | 3qxvC-5gxbB:21.0 | 3qxvC-5gxbB:68.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hvf | VHH-I83 (Vicugna pacos) |
PF07686(V-set) | 6 | VAL B 2ALA B 24MET B 34ASN B 72VAL B 77ALA B 96 | None | 1.15A | 3qxvC-5hvfB:18.9 | 3qxvC-5hvfB:69.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5iml | NANOBODY (Camelidae) |
PF07686(V-set) | 6 | ALA B 23MET B 33ARG B 71ASN B 73VAL B 78ALA B 97 | None | 0.72A | 3qxvC-5imlB:24.1 | 3qxvC-5imlB:75.40 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5j1s | VHH DOMAIN BS-2 (Vicugna pacos) |
PF07686(V-set) | 6 | ALA C 25MET C 35ARG C 72ASN C 74VAL C 79ALA C 98 | None | 0.90A | 3qxvC-5j1sC:19.7 | 3qxvC-5j1sC:66.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5j1s | VHH DOMAIN BS-2 (Vicugna pacos) |
PF07686(V-set) | 5 | VAL C 3ALA C 25MET C 35VAL C 79ALA C 98 | None | 0.72A | 3qxvC-5j1sC:19.7 | 3qxvC-5j1sC:66.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5j57 | VHH SINGLE CHAINANTIBODY V5E1 (Vicugna pacos) |
PF07686(V-set) | 5 | ALA B 24ARG B 72ASN B 74VAL B 79ALA B 98 | None | 0.44A | 3qxvC-5j57B:20.9 | 3qxvC-5j57B:65.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ja8 | NANOBODY 2 (Lama glama) |
PF07686(V-set) | 6 | VAL B 3ALA B 25ARG B 73ASN B 75VAL B 80ALA B 99 | None | 0.66A | 3qxvC-5ja8B:20.4 | 3qxvC-5ja8B:70.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ja9 | NANOBODY 6 (Lama glama) |
PF07686(V-set) | 6 | VAL A 3ALA A 25MET A 35ARG A 73ASN A 75ALA A 99 | None | 0.89A | 3qxvC-5ja9A:20.4 | 3qxvC-5ja9A:68.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5jmo | CAMELID VHH FRAGMENT (Camelusdromedarius) |
PF07686(V-set) | 5 | VAL C 2ALA C 24MET C 34ARG C 72ASN C 74 | None | 0.80A | 3qxvC-5jmoC:20.2 | 3qxvC-5jmoC:63.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5jqh | NANOBODY60, NB60 (Lama glama) |
no annotation | 5 | MET D 34ARG D 71ASN D 73VAL D 78ALA D 97 | None | 0.75A | 3qxvC-5jqhD:19.5 | 3qxvC-5jqhD:70.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5lhq | CAMELID-DERIVEDANTIBODY FRAGMENTNB7 (Vicugna pacos) |
PF07686(V-set) | 6 | VAL B 2ALA B 24ARG B 72ASN B 74VAL B 79ALA B 98 | None | 0.57A | 3qxvC-5lhqB:21.9 | 3qxvC-5lhqB:64.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5lhr | CAMELID-DERIVEDANTIBODY FRAGMENTNB22 (Vicugna pacos) |
PF07686(V-set) | 6 | ALA B 24MET B 34ARG B 72ASN B 74VAL B 79ALA B 98 | None | 0.89A | 3qxvC-5lhrB:20.2 | 3qxvC-5lhrB:76.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5lmj | NANOBODY (Lama glama) |
PF07686(V-set) | 6 | ALA A 24MET A 34ARG A 71ASN A 73VAL A 78ALA A 94 | None | 0.93A | 3qxvC-5lmjA:20.4 | 3qxvC-5lmjA:73.23 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5lmj | NANOBODY (Lama glama) |
PF07686(V-set) | 6 | VAL A 2ALA A 24ARG A 71ASN A 73VAL A 78ALA A 94 | None | 0.84A | 3qxvC-5lmjA:20.4 | 3qxvC-5lmjA:73.23 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5lwf | CAMELID HEAVY-CHAINANTIBODY VARIABLEFRAGMENT CAB-G10S (Lama glama) |
no annotation | 7 | VAL C 5ALA C 27MET C 37ARG C 75ASN C 77VAL C 82ALA C 101 | None | 0.70A | 3qxvC-5lwfC:21.5 | 3qxvC-5lwfC:68.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5mwn | LLAMA NANOBODYRAISED AGAINST TSSK,NBK27 (Lama glama) |
PF07686(V-set) | 5 | VAL N 2ALA N 24MET N 34VAL N 78ALA N 97 | None | 0.78A | 3qxvC-5mwnN:18.2 | 3qxvC-5mwnN:67.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5o02 | NANOBODY (VHH)NANO-4 (Vicugna pacos) |
PF07686(V-set) | 5 | VAL C 2MET C 34ARG C 72ASN C 74ALA C 98 | None | 0.47A | 3qxvC-5o02C:21.6 | 3qxvC-5o02C:68.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5o04 | NANOBODY (VHH)NANO-26 (Vicugna pacos) |
PF07686(V-set) | 5 | VAL E 2ALA E 24ARG E 71ASN E 73VAL E 78 | None | 0.66A | 3qxvC-5o04E:18.8 | 3qxvC-5o04E:65.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5o8f | NANOBODY NB25 (Lama glama) |
no annotation | 5 | MET L 34ARG L 72ASN L 74VAL L 79ALA L 98 | None | 0.44A | 3qxvC-5o8fL:21.7 | 3qxvC-5o8fL:68.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5omn | NANOBODY (VHH)NANO-27 (Vicugna pacos) |
PF07686(V-set) | 5 | VAL C 2ALA C 24MET C 34ARG C 71ASN C 73 | None | 0.77A | 3qxvC-5omnC:19.7 | 3qxvC-5omnC:65.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ovw | NANOBODY (Lama glama) |
no annotation | 5 | ALA G 46ARG G 94ASN G 96VAL G 101ALA G 120 | None | 0.44A | 3qxvC-5ovwG:21.7 | 3qxvC-5ovwG:59.57 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5tr8 | 441D6 FAB HEAVYCHAIN (Mus musculus) |
no annotation | 5 | VAL H 2ALA H 24MET H 34ARG H 71ASN H 73 | None | 0.80A | 3qxvC-5tr8H:19.1 | 3qxvC-5tr8H:54.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5u68 | MPE8 (Homo sapiens) |
PF07686(V-set) | 5 | VAL E 21ALA E 43MET E 53ARG E 91ASN E 93 | None | 0.80A | 3qxvC-5u68E:21.0 | 3qxvC-5u68E:61.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5uk4 | ANTI-VESICULARSTOMATITIS VIRUS NVHH (Vicugna pacos) |
no annotation | 6 | VAL p 2MET p 34ARG p 72ASN p 74VAL p 79ALA p 98 | None | 0.69A | 3qxvC-5uk4p:21.6 | 3qxvC-5uk4p:71.43 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5vaq | NB914 (Lama glama) |
no annotation | 6 | ALA B 24SER B 30ARG B 72ASN B 74VAL B 79ALA B 98 | None | 0.98A | 3qxvC-5vaqB:23.3 | 3qxvC-5vaqB:75.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vf6 | SINGLE CHAINVARIABLE FRAGMENT (Gallus gallus) |
no annotation | 6 | VAL A 125ALA A 147MET A 157ARG A 195ASN A 197VAL A 202 | None | 0.97A | 3qxvC-5vf6A:20.4 | 3qxvC-5vf6A:21.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5vk2 | FAB 37.7H HEAVYCHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 5 | VAL D 3ALA D 25MET D 35ARG D 74ASN D 76 | None | 0.79A | 3qxvC-5vk2D:20.5 | 3qxvC-5vk2D:40.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5vxj | SINGLE-DOMAINANTIBODY JMK-E3 (Vicugna pacos) |
no annotation | 6 | VAL B 2MET B 34ARG B 72ASN B 74VAL B 79ALA B 98 | None | 0.71A | 3qxvC-5vxjB:19.5 | 3qxvC-5vxjB:63.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5vxl | SINGLE-DOMAINANTIBODY JPS-G3 (Vicugna pacos) |
no annotation | 6 | ALA B 24MET B 34ARG B 73ASN B 75VAL B 80ALA B 99 | None | 0.74A | 3qxvC-5vxlB:20.3 | 3qxvC-5vxlB:66.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5vxm | SINGLE-DOMAINANTIBODY 20IPAD (Vicugna pacos) |
no annotation | 5 | VAL B 2ARG B 72ASN B 74VAL B 79ALA B 98 | None | 0.70A | 3qxvC-5vxmB:23.0 | 3qxvC-5vxmB:70.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wb1 | ENVELOPE PROTEINUS28, NANOBODY 7FUSION PROTEIN (Humanbetaherpesvirus5;Lama glama) |
no annotation | 6 | VAL A1002ALA A1024MET A1034ASN A1073VAL A1078ALA A1097 | None | 0.94A | 3qxvC-5wb1A:18.3 | 3qxvC-5wb1A:15.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5xaj | FABHM14C10 HEAVYCHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 5 | VAL A 2ALA A 24MET A 34ASN A 74VAL A 79 | None | 0.78A | 3qxvC-5xajA:21.2 | 3qxvC-5xajA:64.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5y9f | HEAVY CHAIN OF FABFRAGMENT OF ANTIBODY28F10 (Mus musculus) |
no annotation | 5 | VAL L 2ALA L 24MET L 34ARG L 72ASN L 74 | None | 0.74A | 3qxvC-5y9fL:20.3 | 3qxvC-5y9fL:57.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yy5 | - (-) |
no annotation | 5 | VAL C 2ALA C 24MET C 34ARG C 71ASN C 73 | None | 0.69A | 3qxvC-5yy5C:19.6 | 3qxvC-5yy5C:undetectable | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6d11 | 1450 ANTIBODY, HEAVYCHAIN (Homo sapiens) |
no annotation | 5 | VAL A 2MET A 34ARG A 71ASN A 73VAL A 78 | None | 0.55A | 3qxvC-6d11A:20.1 | 3qxvC-6d11A:44.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6ehg | HC3NB1 (Lama glama) |
no annotation | 6 | ALA C 24MET C 34ARG C 72ASN C 74VAL C 79ALA C 98 | None | 0.70A | 3qxvC-6ehgC:22.4 | 3qxvC-6ehgC:57.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6fe4 | NB113 (Vicugna pacos) |
no annotation | 5 | VAL F 2ALA F 24MET F 34ARG F 72ASN F 74 | None | 0.81A | 3qxvC-6fe4F:20.8 | 3qxvC-6fe4F:66.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gzp | NANOBODY (Lama glama) |
no annotation | 6 | VAL A 2ALA A 24MET A 34ARG A 71ASN A 73ALA A 94 | None | 0.71A | 3qxvC-6gzpA:22.0 | 3qxvC-6gzpA:undetectable | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 8fab | IGG1-LAMBDA HIL FAB(HEAVY CHAIN) (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 5 | VAL B 2ALA B 24MET B 34ARG B 72ASN B 74 | None | 0.79A | 3qxvC-8fabB:22.0 | 3qxvC-8fabB:59.52 |