SIMILAR PATTERNS OF AMINO ACIDS FOR 3QXV_C_MTXC2000

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1kxt IMMUNOGLOBULIN VHH
FRAGMENT


(Camelus
dromedarius)
PF07686
(V-set)
6 VAL B   2
ALA B  24
MET B  34
ARG B  71
ASN B  73
ALA B  94
None
0.97A 3qxvC-1kxtB:
19.5
3qxvC-1kxtB:
68.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1pz5 HEAVY CHAIN OF FAB
(SYA/J6)


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
5 VAL B   2
ALA B  24
MET B  34
ARG B  71
VAL B  78
None
0.83A 3qxvC-1pz5B:
20.2
3qxvC-1pz5B:
51.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2aeq FAB HEAVY CHAIN

(Mus musculus)
PF07686
(V-set)
5 VAL H   2
MET H  34
ARG H  74
ASN H  76
VAL H  81
None
0.82A 3qxvC-2aeqH:
18.2
3qxvC-2aeqH:
33.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2fl5 IMMUNOGLOBULIN IGG1
HEAVY CHAIN


(Homo sapiens)
no annotation 5 VAL H   2
ALA H  24
MET H  34
ARG H  71
ASN H  73
None
0.77A 3qxvC-2fl5H:
20.8
3qxvC-2fl5H:
35.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jgv TAGATOSE-6-PHOSPHATE
KINASE


(Staphylococcus
aureus)
PF00294
(PfkB)
6 VAL A 239
ALA A 230
ARG A 238
SER A 222
VAL A 181
ALA A 277
None
1.08A 3qxvC-2jgvA:
undetectable
3qxvC-2jgvA:
16.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2uzi ANTI-RAS FV HEAVY
CHAIN


(Homo sapiens)
PF07686
(V-set)
5 VAL H   2
ALA H  24
MET H  34
ARG H  72
ASN H  74
None
0.79A 3qxvC-2uziH:
21.4
3qxvC-2uziH:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2xa3 LLAMA HEAVY CHAIN
ANTIBODY D7


(Lama glama)
PF07686
(V-set)
5 SER A  29
MET A  34
ASN A  73
VAL A  78
ALA A  94
SO4  A1114 (-2.7A)
None
None
None
None
0.80A 3qxvC-2xa3A:
21.2
3qxvC-2xa3A:
69.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3g9a MINIMIZER

(Camelus
dromedarius)
PF07686
(V-set)
5 ALA B  24
MET B  34
ARG B  71
VAL B  78
ALA B  94
None
0.71A 3qxvC-3g9aB:
20.0
3qxvC-3g9aB:
64.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3k7u ANTIBODY

(Lama glama)
PF07686
(V-set)
5 MET A  34
ARG A  72
ASN A  74
VAL A  79
ALA A  98
None
0.28A 3qxvC-3k7uA:
22.1
3qxvC-3k7uA:
73.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ln9 IMMUNOGLOBULIN HEAVY
CHAIN ANTIBODY
VARIABLE DOMAIN B10


(Camelidae)
PF07686
(V-set)
6 VAL A   2
ALA A  24
ARG A  72
ASN A  74
VAL A  79
ALA A  98
None
0.85A 3qxvC-3ln9A:
19.7
3qxvC-3ln9A:
67.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3piq HUMAN MONOCLONAL
ANTIBODY 2909 FAB
HEAVY CHAIN


(Homo sapiens)
no annotation 5 VAL H   2
ALA H  24
MET H  34
ARG H  71
ASN H  73
None
0.80A 3qxvC-3piqH:
19.6
3qxvC-3piqH:
56.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3qxu ANTI-METHOTREXATE
CDR1-3 GRAFT


(Lama glama)
PF07686
(V-set)
7 VAL A   4
ALA A  26
SER A  30
MET A  36
ARG A  74
VAL A  81
ALA A 100
None
0.89A 3qxvC-3qxuA:
24.5
3qxvC-3qxuA:
96.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3qyc VH DOMAIN OF IGG
MOLECULE


(Homo sapiens)
PF07686
(V-set)
5 ALA A  26
MET A  36
ARG A  74
ASN A  76
VAL A  81
None
0.73A 3qxvC-3qycA:
20.1
3qxvC-3qycA:
61.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3qyc VH DOMAIN OF IGG
MOLECULE


(Homo sapiens)
PF07686
(V-set)
5 VAL A   4
ALA A  26
MET A  36
ARG A  74
VAL A  81
None
0.83A 3qxvC-3qycA:
20.1
3qxvC-3qycA:
61.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3r0m LLAMA VHH A12

(Lama glama)
PF07686
(V-set)
6 ALA A  24
SER A  29
MET A  34
ASN A  73
VAL A  78
ALA A  94
None
SO4  A 131 (-2.7A)
None
None
None
None
1.12A 3qxvC-3r0mA:
21.2
3qxvC-3r0mA:
70.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3stb SINGLE DOMAIN
ANTIBODY VHH


(Lama glama)
PF07686
(V-set)
6 ALA A  26
MET A  36
ARG A  73
ASN A  75
VAL A  80
ALA A  99
None
0.71A 3qxvC-3stbA:
22.5
3qxvC-3stbA:
70.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4dgy HCV1 HEAVY CHAIN

(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
5 VAL H   2
ALA H  24
MET H  34
ARG H  71
ASN H  73
GOL  H 302 (-4.1A)
None
None
None
None
0.80A 3qxvC-4dgyH:
20.6
3qxvC-4dgyH:
37.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4dka SINGLE DOMAIN
ANTIBODY VHH


(Lama glama)
PF07686
(V-set)
6 ALA A  24
MET A  34
ARG A  72
ASN A  74
VAL A  79
ALA A  98
None
0.78A 3qxvC-4dkaA:
22.3
3qxvC-4dkaA:
73.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4eig CA1698 CAMEL
ANTIBODY FRAGMENT


(Lama glama)
PF07686
(V-set)
6 ALA B  24
MET B  34
ARG B  71
ASN B  73
VAL B  78
ALA B  97
None
0.75A 3qxvC-4eigB:
20.5
3qxvC-4eigB:
66.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ej1 NB113 CAMELID
ANTIBODY FRAGMENT


(Lama glama)
PF07686
(V-set)
5 ALA C  24
MET C  34
ASN C  74
VAL C  79
ALA C  98
None
0.70A 3qxvC-4ej1C:
21.7
3qxvC-4ej1C:
74.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ej1 NB113 CAMELID
ANTIBODY FRAGMENT


(Lama glama)
PF07686
(V-set)
5 MET C  34
ARG C  72
ASN C  74
VAL C  79
ALA C  98
None
0.38A 3qxvC-4ej1C:
21.7
3qxvC-4ej1C:
74.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4fhb NB179

(Lama glama)
PF07686
(V-set)
5 MET D  34
ARG D  72
ASN D  74
VAL D  79
ALA D  98
None
0.50A 3qxvC-4fhbD:
21.4
3qxvC-4fhbD:
71.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4fql MONOCLONAL ANTIBODY
CR8033 HEAVY CHAIN


(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
5 VAL H   2
ALA H  24
MET H  34
ARG H  71
ASN H  73
None
0.75A 3qxvC-4fqlH:
21.7
3qxvC-4fqlH:
59.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4gft NANOBODY

(Lama glama)
PF07686
(V-set)
5 MET B  36
ARG B  74
ASN B  76
VAL B  81
ALA B 100
None
0.26A 3qxvC-4gftB:
22.7
3qxvC-4gftB:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4glr ANTI-PTAU HEAVY
CHAIN


(Gallus gallus)
PF07654
(C1-set)
PF07686
(V-set)
5 VAL H   2
MET H  34
ARG H  71
ASN H  73
VAL H  78
None
0.60A 3qxvC-4glrH:
21.1
3qxvC-4glrH:
30.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hem ANTI-BASEPLATE
TP901-1 LLAMA VHH 02


(Lama glama)
PF07686
(V-set)
6 ALA E  24
MET E  34
ARG E  72
ASN E  74
VAL E  79
ALA E  98
None
0.68A 3qxvC-4hemE:
23.2
3qxvC-4hemE:
73.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4kfz ANTI-LMO2 VH

(Homo sapiens)
PF07686
(V-set)
6 VAL C   2
ALA C  24
SER C  28
MET C  34
ARG C  72
ASN C  74
None
0.90A 3qxvC-4kfzC:
20.1
3qxvC-4kfzC:
61.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4krm NANOBODY/VHH DOMAIN
7D12


(Lama glama)
PF07686
(V-set)
5 ALA B  24
MET B  34
ARG B  72
VAL B  79
ALA B  98
None
0.70A 3qxvC-4krmB:
23.8
3qxvC-4krmB:
70.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4krm NANOBODY/VHH DOMAIN
7D12


(Lama glama)
PF07686
(V-set)
5 MET B  34
ARG B  72
ASN B  74
VAL B  79
ALA B  98
None
0.34A 3qxvC-4krmB:
23.8
3qxvC-4krmB:
70.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4lhq CAMELID NANOBODY

(Vicugna pacos)
PF07686
(V-set)
5 SER B  28
MET B  34
ARG B  72
ASN B  74
VAL B  79
None
0.64A 3qxvC-4lhqB:
22.0
3qxvC-4lhqB:
63.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4n1h CAMELID HEAVY-CHAIN
ANTIBODY VARIABLE
FRAGMENT CAB-F11N


(Lama glama)
PF07686
(V-set)
5 ALA B  24
MET B  34
ASN B  74
VAL B  79
ALA B  98
None
0.69A 3qxvC-4n1hB:
21.6
3qxvC-4n1hB:
68.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4n1h CAMELID HEAVY-CHAIN
ANTIBODY VARIABLE
FRAGMENT CAB-F11N


(Lama glama)
PF07686
(V-set)
5 MET B  34
ARG B  72
ASN B  74
VAL B  79
ALA B  98
None
0.44A 3qxvC-4n1hB:
21.6
3qxvC-4n1hB:
68.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4nc1 A20.1 VHH

(Lama glama)
PF07686
(V-set)
7 VAL C   9
ALA C  31
MET C  41
ARG C  79
ASN C  81
VAL C  86
ALA C 105
None
0.93A 3qxvC-4nc1C:
22.2
3qxvC-4nc1C:
70.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4nc2 B39 VHH

(Lama glama)
PF07686
(V-set)
6 VAL B   2
ALA B  24
MET B  34
ARG B  71
ASN B  73
ALA B  97
None
0.73A 3qxvC-4nc2B:
23.2
3qxvC-4nc2B:
70.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ocr CAP256-VRC26.01
HEAVY CHAIN


(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
5 VAL H   2
MET H  34
ARG H  71
ASN H  73
VAL H  78
None
0.53A 3qxvC-4ocrH:
21.7
3qxvC-4ocrH:
54.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ouo ANTI BLA G 1 SCFV

(Gallus gallus)
PF07686
(V-set)
6 VAL A 116
ALA A 138
MET A 148
ARG A 185
ASN A 187
VAL A 192
None
0.90A 3qxvC-4ouoA:
20.9
3qxvC-4ouoA:
27.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4p2c NANOBODY 1,
ANTI-F4+ETEC
BACTERIA VHH
VARIABLE REGION


(Lama glama)
PF07686
(V-set)
6 VAL G   2
MET G  34
ARG G  71
ASN G  73
VAL G  78
ALA G  97
None
0.57A 3qxvC-4p2cG:
19.1
3qxvC-4p2cG:
70.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4p49 ANTIBODY SCFV B8

(Gallus gallus)
PF07686
(V-set)
6 VAL A 122
ALA A 144
MET A 154
ARG A 193
ASN A 195
VAL A 200
None
0.93A 3qxvC-4p49A:
22.0
3qxvC-4p49A:
51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4qlr LLAMA NANOBODY N02
VH DOMAIN


(Lama glama)
PF07686
(V-set)
5 ALA A  24
ARG A  72
ASN A  74
VAL A  79
ALA A  98
None
0.76A 3qxvC-4qlrA:
22.5
3qxvC-4qlrA:
69.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4qo1 NB139 NANOBODY
AGAINST THE
DNA-BINDING DOMAIN
OF P53


(Lama glama)
PF07686
(V-set)
6 ALA A  25
MET A  35
ARG A  73
ASN A  75
VAL A  80
ALA A  99
None
0.58A 3qxvC-4qo1A:
21.5
3qxvC-4qo1A:
62.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4tvs VHH DOMAIN BS-1

(Vicugna pacos)
PF05609
(LAP1C)
5 ALA a  25
ARG a  73
ASN a  75
VAL a  80
ALA a  99
None
0.81A 3qxvC-4tvsa:
22.6
3qxvC-4tvsa:
72.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ut6 BROADLY NEUTRALIZING
HUMAN ANTIBODY EDE2
B7


(Homo sapiens)
PF07686
(V-set)
5 VAL H   2
MET H  34
ARG H  71
ASN H  73
VAL H  78
None
0.77A 3qxvC-4ut6H:
18.9
3qxvC-4ut6H:
57.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4w6y NANOBODY NBFEDF9

(Lama glama)
PF07686
(V-set)
6 VAL B   2
ALA B  24
MET B  34
ASN B  74
VAL B  79
ALA B  98
None
None
None
SO4  B 201 (-4.0A)
None
None
0.97A 3qxvC-4w6yB:
21.3
3qxvC-4w6yB:
69.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4weu ANTI-F4+ETEC
BACTERIA VHH
VARIABLE REGION


(Lama glama)
PF07686
(V-set)
6 VAL D 802
ALA D 824
MET D 834
ARG D 872
ASN D 874
ALA D 898
None
0.70A 3qxvC-4weuD:
22.4
3qxvC-4weuD:
72.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4xt1 NANOBODY 7

(Vicugna pacos)
PF07686
(V-set)
6 VAL C   2
ALA C  24
MET C  34
ASN C  73
VAL C  78
ALA C  97
None
0.89A 3qxvC-4xt1C:
19.3
3qxvC-4xt1C:
68.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4y5v DIABODY 305 VH
DOMAIN


(Homo sapiens)
PF07686
(V-set)
5 VAL A   2
MET A  34
ARG A  72
ASN A  74
VAL A  79
None
0.53A 3qxvC-4y5vA:
21.1
3qxvC-4y5vA:
66.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ybq ANTIBODY FV FRAGMENT
HEAVY CHAIN


(Mus musculus)
PF07686
(V-set)
5 VAL D   3
ALA D  25
MET D  35
ARG D  73
ASN D  75
None
0.80A 3qxvC-4ybqD:
21.2
3qxvC-4ybqD:
58.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ydv HIV ANTIBODY 7B2
HEAVY CHAIN,IGG H
CHAIN


(Homo sapiens)
no annotation 5 VAL H   2
MET H  34
ARG H  71
ASN H  72
VAL H  75
None
0.66A 3qxvC-4ydvH:
19.3
3qxvC-4ydvH:
37.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4yga VHH-1B7

(Vicugna pacos)
PF07686
(V-set)
6 VAL B   3
ALA B  25
ARG B  73
ASN B  75
VAL B  80
ALA B  99
None
0.72A 3qxvC-4ygaB:
20.5
3qxvC-4ygaB:
60.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5aum HEAVY CHAIN OF FAB
FRAGMENT


(Rattus)
no annotation 6 VAL H   2
ALA H  24
MET H  34
ARG H  71
VAL H  78
ALA H  94
None
0.70A 3qxvC-5aumH:
20.0
3qxvC-5aumH:
38.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5b6f ANTI-LEUKOTRIENE C4
MONOCLONAL ANTIBODY
IMMUNOGLOBULIN
GAMMA1 HEAVY CHAIN


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
5 VAL B  21
ALA B  43
MET B  53
ARG B  93
VAL B 100
None
0.80A 3qxvC-5b6fB:
19.5
3qxvC-5b6fB:
35.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5bop NANOBODY

(Lama glama)
PF07686
(V-set)
5 MET A  34
ARG A  72
ASN A  74
VAL A  79
ALA A  98
None
0.53A 3qxvC-5bopA:
22.6
3qxvC-5bopA:
69.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5drz HIV ANTIBODY F240
HEAVY CHAIN


(Homo sapiens)
no annotation 5 VAL H   2
MET H  34
ARG H  71
ASN H  73
VAL H  78
None
0.56A 3qxvC-5drzH:
18.9
3qxvC-5drzH:
55.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dxw PD-L1 NANOBODY

(Mus musculus)
PF07686
(V-set)
5 VAL A   4
MET A  36
ARG A  74
ASN A  76
VAL A  81
None
0.74A 3qxvC-5dxwA:
20.7
3qxvC-5dxwA:
65.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5e1h F8(JOB10) VHH
ANTIBODY


(Vicugna pacos)
PF07686
(V-set)
6 VAL B   2
ALA B  24
MET B  34
ARG B  72
ASN B  74
VAL B  79
None
0.93A 3qxvC-5e1hB:
20.8
3qxvC-5e1hB:
68.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5e7f NANOBODY L06

(Camelus
dromedarius)
PF07686
(V-set)
6 VAL A   4
ALA A  26
ARG A  73
ASN A  75
VAL A  80
ALA A  99
None
0.88A 3qxvC-5e7fA:
18.6
3qxvC-5e7fA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5e7f NANOBODY L06

(Camelus
dromedarius)
PF07686
(V-set)
6 VAL A   4
MET A  36
ARG A  73
ASN A  75
VAL A  80
ALA A  99
None
0.64A 3qxvC-5e7fA:
18.6
3qxvC-5e7fA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5f1k NANOBODY MU1053

(Lama glama)
PF07686
(V-set)
5 MET C  34
ARG C  72
ASN C  74
VAL C  79
ALA C  98
None
0.46A 3qxvC-5f1kC:
22.3
3qxvC-5f1kC:
67.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5f1o NANOBODY MU551

(Lama glama)
PF07686
(V-set)
5 MET B  34
ARG B  72
ASN B  74
VAL B  79
ALA B  98
None
0.39A 3qxvC-5f1oB:
21.5
3qxvC-5f1oB:
65.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5fhc ANTIBODY 114 FAB
HEAVY CHAIN


(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
5 VAL H   2
ALA H  24
MET H  34
ARG H  71
ASN H  73
None
0.81A 3qxvC-5fhcH:
20.4
3qxvC-5fhcH:
37.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5fwo NANOBODY

(Lama glama)
PF07686
(V-set)
7 VAL A   2
ALA A  24
MET A  34
ARG A  71
ASN A  73
VAL A  78
ALA A  94
None
0.81A 3qxvC-5fwoA:
21.8
3qxvC-5fwoA:
68.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5gxb NANOBODY

(Vicugna pacos)
PF07686
(V-set)
6 VAL B   2
ALA B  24
MET B  34
ASN B  74
VAL B  79
ALA B  98
None
0.89A 3qxvC-5gxbB:
21.0
3qxvC-5gxbB:
68.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5hvf VHH-I83

(Vicugna pacos)
PF07686
(V-set)
6 VAL B   2
ALA B  24
MET B  34
ASN B  72
VAL B  77
ALA B  96
None
1.15A 3qxvC-5hvfB:
18.9
3qxvC-5hvfB:
69.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5iml NANOBODY

(Camelidae)
PF07686
(V-set)
6 ALA B  23
MET B  33
ARG B  71
ASN B  73
VAL B  78
ALA B  97
None
0.72A 3qxvC-5imlB:
24.1
3qxvC-5imlB:
75.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5j1s VHH DOMAIN BS-2

(Vicugna pacos)
PF07686
(V-set)
6 ALA C  25
MET C  35
ARG C  72
ASN C  74
VAL C  79
ALA C  98
None
0.90A 3qxvC-5j1sC:
19.7
3qxvC-5j1sC:
66.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5j1s VHH DOMAIN BS-2

(Vicugna pacos)
PF07686
(V-set)
5 VAL C   3
ALA C  25
MET C  35
VAL C  79
ALA C  98
None
0.72A 3qxvC-5j1sC:
19.7
3qxvC-5j1sC:
66.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5j57 VHH SINGLE CHAIN
ANTIBODY V5E1


(Vicugna pacos)
PF07686
(V-set)
5 ALA B  24
ARG B  72
ASN B  74
VAL B  79
ALA B  98
None
0.44A 3qxvC-5j57B:
20.9
3qxvC-5j57B:
65.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ja8 NANOBODY 2

(Lama glama)
PF07686
(V-set)
6 VAL B   3
ALA B  25
ARG B  73
ASN B  75
VAL B  80
ALA B  99
None
0.66A 3qxvC-5ja8B:
20.4
3qxvC-5ja8B:
70.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ja9 NANOBODY 6

(Lama glama)
PF07686
(V-set)
6 VAL A   3
ALA A  25
MET A  35
ARG A  73
ASN A  75
ALA A  99
None
0.89A 3qxvC-5ja9A:
20.4
3qxvC-5ja9A:
68.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5jmo CAMELID VHH FRAGMENT

(Camelus
dromedarius)
PF07686
(V-set)
5 VAL C   2
ALA C  24
MET C  34
ARG C  72
ASN C  74
None
0.80A 3qxvC-5jmoC:
20.2
3qxvC-5jmoC:
63.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5jqh NANOBODY60, NB60

(Lama glama)
no annotation 5 MET D  34
ARG D  71
ASN D  73
VAL D  78
ALA D  97
None
0.75A 3qxvC-5jqhD:
19.5
3qxvC-5jqhD:
70.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5lhq CAMELID-DERIVED
ANTIBODY FRAGMENT
NB7


(Vicugna pacos)
PF07686
(V-set)
6 VAL B   2
ALA B  24
ARG B  72
ASN B  74
VAL B  79
ALA B  98
None
0.57A 3qxvC-5lhqB:
21.9
3qxvC-5lhqB:
64.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5lhr CAMELID-DERIVED
ANTIBODY FRAGMENT
NB22


(Vicugna pacos)
PF07686
(V-set)
6 ALA B  24
MET B  34
ARG B  72
ASN B  74
VAL B  79
ALA B  98
None
0.89A 3qxvC-5lhrB:
20.2
3qxvC-5lhrB:
76.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5lmj NANOBODY

(Lama glama)
PF07686
(V-set)
6 ALA A  24
MET A  34
ARG A  71
ASN A  73
VAL A  78
ALA A  94
None
0.93A 3qxvC-5lmjA:
20.4
3qxvC-5lmjA:
73.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5lmj NANOBODY

(Lama glama)
PF07686
(V-set)
6 VAL A   2
ALA A  24
ARG A  71
ASN A  73
VAL A  78
ALA A  94
None
0.84A 3qxvC-5lmjA:
20.4
3qxvC-5lmjA:
73.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5lwf CAMELID HEAVY-CHAIN
ANTIBODY VARIABLE
FRAGMENT CAB-G10S


(Lama glama)
no annotation 7 VAL C   5
ALA C  27
MET C  37
ARG C  75
ASN C  77
VAL C  82
ALA C 101
None
0.70A 3qxvC-5lwfC:
21.5
3qxvC-5lwfC:
68.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5mwn LLAMA NANOBODY
RAISED AGAINST TSSK,
NBK27


(Lama glama)
PF07686
(V-set)
5 VAL N   2
ALA N  24
MET N  34
VAL N  78
ALA N  97
None
0.78A 3qxvC-5mwnN:
18.2
3qxvC-5mwnN:
67.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5o02 NANOBODY (VHH)
NANO-4


(Vicugna pacos)
PF07686
(V-set)
5 VAL C   2
MET C  34
ARG C  72
ASN C  74
ALA C  98
None
0.47A 3qxvC-5o02C:
21.6
3qxvC-5o02C:
68.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5o04 NANOBODY (VHH)
NANO-26


(Vicugna pacos)
PF07686
(V-set)
5 VAL E   2
ALA E  24
ARG E  71
ASN E  73
VAL E  78
None
0.66A 3qxvC-5o04E:
18.8
3qxvC-5o04E:
65.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5o8f NANOBODY NB25

(Lama glama)
no annotation 5 MET L  34
ARG L  72
ASN L  74
VAL L  79
ALA L  98
None
0.44A 3qxvC-5o8fL:
21.7
3qxvC-5o8fL:
68.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5omn NANOBODY (VHH)
NANO-27


(Vicugna pacos)
PF07686
(V-set)
5 VAL C   2
ALA C  24
MET C  34
ARG C  71
ASN C  73
None
0.77A 3qxvC-5omnC:
19.7
3qxvC-5omnC:
65.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ovw NANOBODY

(Lama glama)
no annotation 5 ALA G  46
ARG G  94
ASN G  96
VAL G 101
ALA G 120
None
0.44A 3qxvC-5ovwG:
21.7
3qxvC-5ovwG:
59.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5tr8 441D6 FAB HEAVY
CHAIN


(Mus musculus)
no annotation 5 VAL H   2
ALA H  24
MET H  34
ARG H  71
ASN H  73
None
0.80A 3qxvC-5tr8H:
19.1
3qxvC-5tr8H:
54.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5u68 MPE8

(Homo sapiens)
PF07686
(V-set)
5 VAL E  21
ALA E  43
MET E  53
ARG E  91
ASN E  93
None
0.80A 3qxvC-5u68E:
21.0
3qxvC-5u68E:
61.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5uk4 ANTI-VESICULAR
STOMATITIS VIRUS N
VHH


(Vicugna pacos)
no annotation 6 VAL p   2
MET p  34
ARG p  72
ASN p  74
VAL p  79
ALA p  98
None
0.69A 3qxvC-5uk4p:
21.6
3qxvC-5uk4p:
71.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5vaq NB914

(Lama glama)
no annotation 6 ALA B  24
SER B  30
ARG B  72
ASN B  74
VAL B  79
ALA B  98
None
0.98A 3qxvC-5vaqB:
23.3
3qxvC-5vaqB:
75.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vf6 SINGLE CHAIN
VARIABLE FRAGMENT


(Gallus gallus)
no annotation 6 VAL A 125
ALA A 147
MET A 157
ARG A 195
ASN A 197
VAL A 202
None
0.97A 3qxvC-5vf6A:
20.4
3qxvC-5vf6A:
21.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5vk2 FAB 37.7H HEAVY
CHAIN


(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
5 VAL D   3
ALA D  25
MET D  35
ARG D  74
ASN D  76
None
0.79A 3qxvC-5vk2D:
20.5
3qxvC-5vk2D:
40.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5vxj SINGLE-DOMAIN
ANTIBODY JMK-E3


(Vicugna pacos)
no annotation 6 VAL B   2
MET B  34
ARG B  72
ASN B  74
VAL B  79
ALA B  98
None
0.71A 3qxvC-5vxjB:
19.5
3qxvC-5vxjB:
63.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5vxl SINGLE-DOMAIN
ANTIBODY JPS-G3


(Vicugna pacos)
no annotation 6 ALA B  24
MET B  34
ARG B  73
ASN B  75
VAL B  80
ALA B  99
None
0.74A 3qxvC-5vxlB:
20.3
3qxvC-5vxlB:
66.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5vxm SINGLE-DOMAIN
ANTIBODY 20IPAD


(Vicugna pacos)
no annotation 5 VAL B   2
ARG B  72
ASN B  74
VAL B  79
ALA B  98
None
0.70A 3qxvC-5vxmB:
23.0
3qxvC-5vxmB:
70.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wb1 ENVELOPE PROTEIN
US28, NANOBODY 7
FUSION PROTEIN


(Human
betaherpesvirus
5;
Lama glama)
no annotation 6 VAL A1002
ALA A1024
MET A1034
ASN A1073
VAL A1078
ALA A1097
None
0.94A 3qxvC-5wb1A:
18.3
3qxvC-5wb1A:
15.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5xaj FABHM14C10 HEAVY
CHAIN


(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
5 VAL A   2
ALA A  24
MET A  34
ASN A  74
VAL A  79
None
0.78A 3qxvC-5xajA:
21.2
3qxvC-5xajA:
64.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5y9f HEAVY CHAIN OF FAB
FRAGMENT OF ANTIBODY
28F10


(Mus musculus)
no annotation 5 VAL L   2
ALA L  24
MET L  34
ARG L  72
ASN L  74
None
0.74A 3qxvC-5y9fL:
20.3
3qxvC-5y9fL:
57.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yy5 -

(-)
no annotation 5 VAL C   2
ALA C  24
MET C  34
ARG C  71
ASN C  73
None
0.69A 3qxvC-5yy5C:
19.6
3qxvC-5yy5C:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6d11 1450 ANTIBODY, HEAVY
CHAIN


(Homo sapiens)
no annotation 5 VAL A   2
MET A  34
ARG A  71
ASN A  73
VAL A  78
None
0.55A 3qxvC-6d11A:
20.1
3qxvC-6d11A:
44.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6ehg HC3NB1

(Lama glama)
no annotation 6 ALA C  24
MET C  34
ARG C  72
ASN C  74
VAL C  79
ALA C  98
None
0.70A 3qxvC-6ehgC:
22.4
3qxvC-6ehgC:
57.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6fe4 NB113

(Vicugna pacos)
no annotation 5 VAL F   2
ALA F  24
MET F  34
ARG F  72
ASN F  74
None
0.81A 3qxvC-6fe4F:
20.8
3qxvC-6fe4F:
66.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gzp NANOBODY

(Lama glama)
no annotation 6 VAL A   2
ALA A  24
MET A  34
ARG A  71
ASN A  73
ALA A  94
None
0.71A 3qxvC-6gzpA:
22.0
3qxvC-6gzpA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
8fab IGG1-LAMBDA HIL FAB
(HEAVY CHAIN)


(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
5 VAL B   2
ALA B  24
MET B  34
ARG B  72
ASN B  74
None
0.79A 3qxvC-8fabB:
22.0
3qxvC-8fabB:
59.52