SIMILAR PATTERNS OF AMINO ACIDS FOR 3QXV_A_MTXA2000_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1i3u | ANTIBODY VHH LAMADOMAIN (Lama glama) |
PF07686(V-set) | 6 | ALA A 24ARG A 77ASN A 79VAL A 84ALA A 103TYR A 118 | NoneNoneNoneNoneNoneCGN A 1 ( 4.0A) | 0.86A | 3qxvA-1i3uA:21.0 | 3qxvA-1i3uA:59.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1kxt | IMMUNOGLOBULIN VHHFRAGMENT (Camelusdromedarius) |
PF07686(V-set) | 6 | VAL B 2ALA B 24MET B 34ASN B 73ALA B 94TYR B 102 | None | 0.99A | 3qxvA-1kxtB:19.2 | 3qxvA-1kxtB:68.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1t66 | IMMUNOGLOBULIN HEAVYCHAIN (Mus musculus) |
no annotation | 6 | VAL H 2ALA H 24MET H 34ARG H 74VAL H 81TYR H 107 | None | 0.86A | 3qxvA-1t66H:19.3 | 3qxvA-1t66H:31.43 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2fbj | IGA-KAPPA J539 FAB(HEAVY CHAIN) (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 6 | VAL H 2ALA H 24MET H 34ARG H 72ASN H 74TYR H 107 | None | 1.13A | 3qxvA-2fbjH:19.9 | 3qxvA-2fbjH:31.53 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2x6m | HEAVY CHAIN VARIABLEDOMAIN FROMDROMEDARY (Camelusdromedarius) |
PF07686(V-set) | 6 | ALA A 24MET A 34ASN A 75VAL A 80ALA A 99TYR A 115 | None | 0.81A | 3qxvA-2x6mA:21.3 | 3qxvA-2x6mA:70.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2x6m | HEAVY CHAIN VARIABLEDOMAIN FROMDROMEDARY (Camelusdromedarius) |
PF07686(V-set) | 6 | MET A 34ARG A 73ASN A 75VAL A 80ALA A 99TYR A 115 | None | 1.04A | 3qxvA-2x6mA:21.3 | 3qxvA-2x6mA:70.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2xa3 | LLAMA HEAVY CHAINANTIBODY D7 (Lama glama) |
PF07686(V-set) | 6 | SER A 29MET A 34ASN A 73VAL A 78ALA A 94TYR A 102 | SO4 A1114 (-2.7A)NoneNoneNoneNoneNone | 0.90A | 3qxvA-2xa3A:21.0 | 3qxvA-2xa3A:69.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3g9a | MINIMIZER (Camelusdromedarius) |
PF07686(V-set) | 6 | ALA B 24MET B 34ARG B 71VAL B 78ALA B 94TYR B 102 | None | 0.64A | 3qxvA-3g9aB:19.5 | 3qxvA-3g9aB:64.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3g9a | MINIMIZER (Camelusdromedarius) |
PF07686(V-set) | 6 | VAL B 2ALA B 24MET B 34VAL B 78ALA B 94TYR B 102 | None | 0.87A | 3qxvA-3g9aB:19.5 | 3qxvA-3g9aB:64.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3k7u | ANTIBODY (Lama glama) |
PF07686(V-set) | 6 | MET A 34ARG A 72ASN A 74VAL A 79ALA A 98TYR A 111 | None | 0.36A | 3qxvA-3k7uA:22.0 | 3qxvA-3k7uA:73.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ln9 | IMMUNOGLOBULIN HEAVYCHAIN ANTIBODYVARIABLE DOMAIN B10 (Camelidae) |
PF07686(V-set) | 7 | VAL A 2ALA A 24ARG A 72ASN A 74VAL A 79ALA A 98TYR A 113 | NoneNoneNoneNoneNoneNoneGOL A 137 (-4.8A) | 0.89A | 3qxvA-3ln9A:19.5 | 3qxvA-3ln9A:67.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3qxu | ANTI-METHOTREXATECDR1-3 GRAFT (Lama glama) |
PF07686(V-set) | 7 | SER A 31TRP A 34MET A 36ARG A 74VAL A 81ALA A 100TYR A 120 | None | 1.41A | 3qxvA-3qxuA:24.2 | 3qxvA-3qxuA:96.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3qxu | ANTI-METHOTREXATECDR1-3 GRAFT (Lama glama) |
PF07686(V-set) | 7 | VAL A 4ALA A 26SER A 30MET A 36VAL A 81ALA A 100TYR A 120 | None | 0.94A | 3qxvA-3qxuA:24.2 | 3qxvA-3qxuA:96.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3qxu | ANTI-METHOTREXATECDR1-3 GRAFT (Lama glama) |
PF07686(V-set) | 8 | VAL A 4ALA A 26SER A 31MET A 36ARG A 74VAL A 81ALA A 100TYR A 120 | None | 0.86A | 3qxvA-3qxuA:24.2 | 3qxvA-3qxuA:96.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3stb | SINGLE DOMAINANTIBODY VHH (Lama glama) |
PF07686(V-set) | 6 | ALA A 26MET A 36ARG A 73ASN A 75VAL A 80ALA A 99 | None | 0.68A | 3qxvA-3stbA:22.1 | 3qxvA-3stbA:70.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3tpk | IMMUNOGLOBULIN HEAVYCHAIN ANTIBODYVARIABLE DOMAIN KW1 (Camelidae) |
PF07686(V-set) | 6 | VAL A 2ALA A 24ASN A 74VAL A 79ALA A 98TYR A 110 | NoneBEN A 133 (-3.6A)NoneBEN A 133 (-4.6A)BEN A 133 ( 4.2A)None | 1.30A | 3qxvA-3tpkA:20.3 | 3qxvA-3tpkA:64.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3u0w | FAB HEAVY CHAIN, IGGAMMA-1 CHAIN CREGION (Homo sapiens;Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 6 | VAL H 2ALA H 24MET H 34ARG H 72ASN H 74TYR H 102 | None | 1.05A | 3qxvA-3u0wH:19.8 | 3qxvA-3u0wH:36.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4dka | SINGLE DOMAINANTIBODY VHH (Lama glama) |
PF07686(V-set) | 7 | ALA A 24MET A 34ARG A 72ASN A 74VAL A 79ALA A 98TYR A 116 | None | 0.69A | 3qxvA-4dkaA:22.1 | 3qxvA-4dkaA:73.23 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4dka | SINGLE DOMAINANTIBODY VHH (Lama glama) |
PF07686(V-set) | 7 | ALA A 24SER A 30MET A 34ARG A 72ASN A 74VAL A 79ALA A 98 | None | 1.24A | 3qxvA-4dkaA:22.1 | 3qxvA-4dkaA:73.23 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4dka | SINGLE DOMAINANTIBODY VHH (Lama glama) |
PF07686(V-set) | 7 | VAL A 2ALA A 24MET A 34ARG A 72ASN A 74VAL A 79TYR A 116 | None | 0.91A | 3qxvA-4dkaA:22.1 | 3qxvA-4dkaA:73.23 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4eig | CA1698 CAMELANTIBODY FRAGMENT (Lama glama) |
PF07686(V-set) | 7 | ALA B 24MET B 34ARG B 71ASN B 73VAL B 78ALA B 97TYR B 106 | None | 0.76A | 3qxvA-4eigB:20.2 | 3qxvA-4eigB:66.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ej1 | NB113 CAMELIDANTIBODY FRAGMENT (Lama glama) |
PF07686(V-set) | 5 | MET C 34ARG C 72ASN C 74VAL C 79ALA C 98 | None | 0.34A | 3qxvA-4ej1C:21.6 | 3qxvA-4ej1C:74.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4fhb | NB179 (Lama glama) |
PF07686(V-set) | 6 | MET D 34ARG D 72ASN D 74VAL D 79ALA D 98TYR D 118 | None | 0.58A | 3qxvA-4fhbD:21.2 | 3qxvA-4fhbD:71.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4gft | NANOBODY (Lama glama) |
PF07686(V-set) | 6 | MET B 36ARG B 74ASN B 76VAL B 81ALA B 100TYR B 115 | NoneNoneNoneNoneNonePCA B 2 ( 3.9A) | 0.32A | 3qxvA-4gftB:22.6 | 3qxvA-4gftB:66.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4glr | ANTI-PTAU HEAVYCHAIN (Gallus gallus) |
PF07654(C1-set)PF07686(V-set) | 5 | VAL H 2MET H 34ARG H 71ASN H 73VAL H 78 | None | 0.52A | 3qxvA-4glrH:21.0 | 3qxvA-4glrH:30.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4hem | ANTI-BASEPLATETP901-1 LLAMA VHH 02 (Lama glama) |
PF07686(V-set) | 7 | ALA E 24MET E 34ARG E 72ASN E 74VAL E 79ALA E 98TYR E 112 | None | 0.62A | 3qxvA-4hemE:23.0 | 3qxvA-4hemE:73.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4krm | NANOBODY/VHH DOMAIN7D12 (Lama glama) |
PF07686(V-set) | 6 | MET B 34ARG B 72ASN B 74VAL B 79ALA B 98TYR B 113 | None | 0.43A | 3qxvA-4krmB:23.5 | 3qxvA-4krmB:70.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4lhq | CAMELID NANOBODY (Vicugna pacos) |
PF07686(V-set) | 6 | ALA B 24SER B 28MET B 34ARG B 72ASN B 74VAL B 79 | None | 0.87A | 3qxvA-4lhqB:21.7 | 3qxvA-4lhqB:63.28 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4mqt | NANOBODY 9-8 (Lama glama) |
PF07686(V-set) | 6 | VAL B 2ALA B 24ASN B 77VAL B 82ALA B 101TYR B 110 | None | 0.92A | 3qxvA-4mqtB:19.0 | 3qxvA-4mqtB:64.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4n1h | CAMELID HEAVY-CHAINANTIBODY VARIABLEFRAGMENT CAB-F11N (Lama glama) |
PF07686(V-set) | 5 | MET B 34ARG B 72ASN B 74VAL B 79ALA B 98 | None | 0.47A | 3qxvA-4n1hB:21.5 | 3qxvA-4n1hB:68.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4nc1 | A20.1 VHH (Lama glama) |
PF07686(V-set) | 8 | VAL C 9ALA C 31MET C 41ARG C 79ASN C 81VAL C 86ALA C 105TYR C 119 | None | 0.90A | 3qxvA-4nc1C:21.7 | 3qxvA-4nc1C:70.23 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4nc2 | B39 VHH (Lama glama) |
PF07686(V-set) | 7 | VAL B 2ALA B 24MET B 34ARG B 71ASN B 73ALA B 97TYR B 111 | None | 0.75A | 3qxvA-4nc2B:22.8 | 3qxvA-4nc2B:70.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4nik | SINGLE-CHAIN FVFRAGMENT ANTIBODY (Homo sapiens) |
PF07686(V-set) | 6 | VAL B 4ALA B 26MET B 36ARG B 74ASN B 76TYR B 108 | None | 1.09A | 3qxvA-4nikB:20.3 | 3qxvA-4nikB:32.13 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ocr | CAP256-VRC26.01HEAVY CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 5 | VAL H 2MET H 34ARG H 71ASN H 73VAL H 78 | None | 0.60A | 3qxvA-4ocrH:21.4 | 3qxvA-4ocrH:54.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ouo | ANTI BLA G 1 SCFV (Gallus gallus) |
PF07686(V-set) | 6 | VAL A 116ALA A 138MET A 148ARG A 185ASN A 187VAL A 192 | None | 0.87A | 3qxvA-4ouoA:20.6 | 3qxvA-4ouoA:27.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4p2c | NANOBODY 1,ANTI-F4+ETECBACTERIA VHHVARIABLE REGION (Lama glama) |
PF07686(V-set) | 7 | VAL G 2MET G 34ARG G 71ASN G 73VAL G 78ALA G 97TYR G 111 | None | 0.58A | 3qxvA-4p2cG:18.9 | 3qxvA-4p2cG:70.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4p49 | ANTIBODY SCFV B8 (Gallus gallus) |
PF07686(V-set) | 6 | VAL A 122ALA A 144MET A 154ARG A 193ASN A 195VAL A 200 | None | 0.89A | 3qxvA-4p49A:21.7 | 3qxvA-4p49A:51.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4qlr | LLAMA NANOBODY N02VH DOMAIN (Lama glama) |
PF07686(V-set) | 6 | ALA A 24ARG A 72ASN A 74VAL A 79ALA A 98TYR A 113 | None | 0.73A | 3qxvA-4qlrA:22.2 | 3qxvA-4qlrA:69.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4qo1 | NB139 NANOBODYAGAINST THEDNA-BINDING DOMAINOF P53 (Lama glama) |
PF07686(V-set) | 7 | ALA A 25MET A 35ARG A 73ASN A 75VAL A 80ALA A 99TYR A 113 | None | 0.62A | 3qxvA-4qo1A:21.1 | 3qxvA-4qo1A:62.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4tvs | VHH DOMAIN BS-1 (Vicugna pacos) |
PF05609(LAP1C) | 6 | ALA a 25ARG a 73ASN a 75VAL a 80ALA a 99TYR a 117 | None | 0.72A | 3qxvA-4tvsa:22.3 | 3qxvA-4tvsa:72.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4w6y | NANOBODY NBFEDF9 (Lama glama) |
PF07686(V-set) | 6 | MET B 34ARG B 72ASN B 74VAL B 79ALA B 98TYR B 118 | NoneNoneSO4 B 201 (-4.0A)NoneNoneNone | 1.47A | 3qxvA-4w6yB:21.1 | 3qxvA-4w6yB:69.47 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4w6y | NANOBODY NBFEDF9 (Lama glama) |
PF07686(V-set) | 7 | VAL B 2ALA B 24MET B 34ASN B 74VAL B 79ALA B 98TYR B 118 | NoneNoneNoneSO4 B 201 (-4.0A)NoneNoneNone | 0.97A | 3qxvA-4w6yB:21.1 | 3qxvA-4w6yB:69.47 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4weu | ANTI-F4+ETECBACTERIA VHHVARIABLE REGION (Lama glama) |
PF07686(V-set) | 7 | VAL D 802ALA D 824MET D 834ARG D 872ASN D 874ALA D 898TYR D 910 | None | 0.66A | 3qxvA-4weuD:22.1 | 3qxvA-4weuD:72.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4xt1 | NANOBODY 7 (Vicugna pacos) |
PF07686(V-set) | 7 | VAL C 2ALA C 24MET C 34ASN C 73VAL C 78ALA C 97TYR C 107 | None | 0.92A | 3qxvA-4xt1C:18.9 | 3qxvA-4xt1C:68.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4y5v | DIABODY 305 VHDOMAIN (Homo sapiens) |
PF07686(V-set) | 5 | VAL A 2MET A 34ARG A 72ASN A 74VAL A 79 | None | 0.46A | 3qxvA-4y5vA:20.7 | 3qxvA-4y5vA:66.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ybq | ANTIBODY FV FRAGMENTHEAVY CHAIN (Mus musculus) |
PF07686(V-set) | 6 | VAL D 3ALA D 25MET D 35ARG D 73ASN D 75TYR D 109 | None | 1.02A | 3qxvA-4ybqD:20.9 | 3qxvA-4ybqD:58.73 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4yga | VHH-1B7 (Vicugna pacos) |
PF07686(V-set) | 6 | VAL B 3ALA B 25ARG B 73ASN B 75VAL B 80ALA B 99 | None | 0.75A | 3qxvA-4ygaB:20.2 | 3qxvA-4ygaB:60.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a2k | IG LAMBDA-1 CHAIN VREGION S43 (Mus musculus) |
PF07686(V-set) | 6 | VAL H 2ALA H 24MET H 34ARG H 71VAL H 78TYR H 102 | None | 0.77A | 3qxvA-5a2kH:19.9 | 3qxvA-5a2kH:29.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5aum | HEAVY CHAIN OF FABFRAGMENT (Rattus) |
no annotation | 6 | VAL H 2ALA H 24MET H 34ARG H 71VAL H 78ALA H 94 | None | 0.63A | 3qxvA-5aumH:19.7 | 3qxvA-5aumH:38.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5b3n | ANTI-H4K20ME1_SCFV (Mus musculus) |
PF07686(V-set) | 6 | VAL A 4ALA A 26MET A 36ARG A 74ASN A 76TYR A 112 | None | 1.09A | 3qxvA-5b3nA:20.6 | 3qxvA-5b3nA:58.91 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5bop | NANOBODY (Lama glama) |
PF07686(V-set) | 5 | MET A 34ARG A 72ASN A 74VAL A 79ALA A 98 | None | 0.48A | 3qxvA-5bopA:22.3 | 3qxvA-5bopA:69.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5drz | HIV ANTIBODY F240HEAVY CHAIN (Homo sapiens) |
no annotation | 5 | VAL H 2MET H 34ARG H 71ASN H 73VAL H 78 | None | 0.55A | 3qxvA-5drzH:18.8 | 3qxvA-5drzH:55.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5e1h | F8(JOB10) VHHANTIBODY (Vicugna pacos) |
PF07686(V-set) | 6 | VAL B 2ALA B 24MET B 34ARG B 72ASN B 74VAL B 79 | None | 0.85A | 3qxvA-5e1hB:20.5 | 3qxvA-5e1hB:68.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5e7f | NANOBODY L06 (Camelusdromedarius) |
PF07686(V-set) | 6 | VAL A 4ALA A 26ARG A 73ASN A 75VAL A 80ALA A 99 | None | 0.86A | 3qxvA-5e7fA:18.4 | 3qxvA-5e7fA:66.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5e7f | NANOBODY L06 (Camelusdromedarius) |
PF07686(V-set) | 6 | VAL A 4MET A 36ARG A 73ASN A 75VAL A 80ALA A 99 | None | 0.66A | 3qxvA-5e7fA:18.4 | 3qxvA-5e7fA:66.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5f1k | NANOBODY MU1053 (Lama glama) |
PF07686(V-set) | 5 | MET C 34ARG C 72ASN C 74VAL C 79ALA C 98 | None | 0.46A | 3qxvA-5f1kC:22.0 | 3qxvA-5f1kC:67.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5f1o | NANOBODY MU551 (Lama glama) |
PF07686(V-set) | 5 | MET B 34ARG B 72ASN B 74VAL B 79ALA B 98 | None | 0.37A | 3qxvA-5f1oB:21.1 | 3qxvA-5f1oB:65.91 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5fwo | NANOBODY (Lama glama) |
PF07686(V-set) | 8 | VAL A 2ALA A 24MET A 34ARG A 71ASN A 73VAL A 78ALA A 94TYR A 102 | None | 0.81A | 3qxvA-5fwoA:21.4 | 3qxvA-5fwoA:68.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gxb | NANOBODY (Vicugna pacos) |
PF07686(V-set) | 6 | VAL B 2ALA B 24MET B 34ASN B 74VAL B 79ALA B 98 | None | 0.89A | 3qxvA-5gxbB:20.7 | 3qxvA-5gxbB:68.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gxb | NANOBODY (Vicugna pacos) |
PF07686(V-set) | 6 | VAL B 2ALA B 24MET B 34VAL B 79ALA B 98TYR B 118 | None | 1.17A | 3qxvA-5gxbB:20.7 | 3qxvA-5gxbB:68.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hvf | VHH-I83 (Vicugna pacos) |
PF07686(V-set) | 7 | VAL B 2ALA B 24ARG B 70ASN B 72VAL B 77ALA B 96TYR B 108 | None | 0.91A | 3qxvA-5hvfB:18.7 | 3qxvA-5hvfB:69.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hvf | VHH-I83 (Vicugna pacos) |
PF07686(V-set) | 7 | VAL B 2ALA B 24MET B 34ASN B 72VAL B 77ALA B 96TYR B 108 | None | 1.10A | 3qxvA-5hvfB:18.7 | 3qxvA-5hvfB:69.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5iml | NANOBODY (Camelidae) |
PF07686(V-set) | 6 | ALA B 23MET B 33ASN B 73VAL B 78ALA B 97TYR B 113 | None | 0.72A | 3qxvA-5imlB:23.7 | 3qxvA-5imlB:75.40 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5iml | NANOBODY (Camelidae) |
PF07686(V-set) | 6 | MET B 33ARG B 71ASN B 73VAL B 78ALA B 97TYR B 113 | None | 0.30A | 3qxvA-5imlB:23.7 | 3qxvA-5imlB:75.40 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5j1s | VHH DOMAIN BS-2 (Vicugna pacos) |
PF07686(V-set) | 7 | ALA C 25MET C 35ARG C 72ASN C 74VAL C 79ALA C 98TYR C 112 | None | 0.86A | 3qxvA-5j1sC:19.3 | 3qxvA-5j1sC:66.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5j1s | VHH DOMAIN BS-2 (Vicugna pacos) |
PF07686(V-set) | 6 | VAL C 3ALA C 25MET C 35VAL C 79ALA C 98TYR C 112 | None | 0.71A | 3qxvA-5j1sC:19.3 | 3qxvA-5j1sC:66.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5j56 | VHH SINGLE CHAINANTIBODY V1C7 (Vicugna pacos) |
PF07686(V-set) | 6 | ALA B 24ARG B 76ASN B 78VAL B 83ALA B 102TYR B 117 | None | 0.91A | 3qxvA-5j56B:20.6 | 3qxvA-5j56B:67.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5j56 | VHH SINGLE CHAINANTIBODY V1C7 (Vicugna pacos) |
PF07686(V-set) | 6 | VAL B 2ALA B 24ARG B 76ASN B 78VAL B 83TYR B 117 | None | 1.18A | 3qxvA-5j56B:20.6 | 3qxvA-5j56B:67.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5j57 | VHH SINGLE CHAINANTIBODY V5E1 (Vicugna pacos) |
PF07686(V-set) | 5 | ALA B 24ARG B 72ASN B 74VAL B 79ALA B 98 | None | 0.44A | 3qxvA-5j57B:20.5 | 3qxvA-5j57B:65.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ja8 | NANOBODY 2 (Lama glama) |
PF07686(V-set) | 5 | ALA B 25ARG B 73ASN B 75VAL B 80ALA B 99 | None | 0.54A | 3qxvA-5ja8B:20.2 | 3qxvA-5ja8B:70.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ja9 | NANOBODY 6 (Lama glama) |
PF07686(V-set) | 6 | VAL A 3ALA A 25MET A 35ARG A 73ASN A 75ALA A 99 | None | 0.88A | 3qxvA-5ja9A:20.2 | 3qxvA-5ja9A:68.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5lhq | CAMELID-DERIVEDANTIBODY FRAGMENTNB7 (Vicugna pacos) |
PF07686(V-set) | 7 | VAL B 2ALA B 24ARG B 72ASN B 74VAL B 79ALA B 98TYR B 122 | None | 0.60A | 3qxvA-5lhqB:21.6 | 3qxvA-5lhqB:64.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5lhr | CAMELID-DERIVEDANTIBODY FRAGMENTNB22 (Vicugna pacos) |
PF07686(V-set) | 6 | MET B 34ARG B 72ASN B 74VAL B 79ALA B 98TYR B 110 | None | 1.29A | 3qxvA-5lhrB:20.1 | 3qxvA-5lhrB:76.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5lmj | NANOBODY (Lama glama) |
PF07686(V-set) | 7 | ALA A 24MET A 34ARG A 71ASN A 73VAL A 78ALA A 94TYR A 102 | None | 0.94A | 3qxvA-5lmjA:20.2 | 3qxvA-5lmjA:73.23 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5lmj | NANOBODY (Lama glama) |
PF07686(V-set) | 7 | VAL A 2ALA A 24ARG A 71ASN A 73VAL A 78ALA A 94TYR A 102 | None | 0.90A | 3qxvA-5lmjA:20.2 | 3qxvA-5lmjA:73.23 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5lwf | CAMELID HEAVY-CHAINANTIBODY VARIABLEFRAGMENT CAB-G10S (Lama glama) |
no annotation | 8 | VAL C 5ALA C 27MET C 37ARG C 75ASN C 77VAL C 82ALA C 101TYR C 117 | NoneNoneNoneNoneNoneNoneNoneACT C 202 (-4.4A) | 0.74A | 3qxvA-5lwfC:21.4 | 3qxvA-5lwfC:68.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5nqw | 026 (Lama glama) |
no annotation | 6 | VAL C 3ALA C 25MET C 35ARG C 73ASN C 75TYR C 112 | None | 1.10A | 3qxvA-5nqwC:21.1 | 3qxvA-5nqwC:44.63 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5o02 | NANOBODY (VHH)NANO-4 (Vicugna pacos) |
PF07686(V-set) | 6 | VAL C 2ALA C 24ARG C 72ASN C 74ALA C 98TYR C 113 | None | 0.87A | 3qxvA-5o02C:21.2 | 3qxvA-5o02C:68.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5o02 | NANOBODY (VHH)NANO-4 (Vicugna pacos) |
PF07686(V-set) | 6 | VAL C 2MET C 34ARG C 72ASN C 74ALA C 98TYR C 113 | None | 0.51A | 3qxvA-5o02C:21.2 | 3qxvA-5o02C:68.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5o04 | NANOBODY (VHH)NANO-26 (Vicugna pacos) |
PF07686(V-set) | 6 | VAL E 2ALA E 24ARG E 71ASN E 73VAL E 78TYR E 104 | None | 0.75A | 3qxvA-5o04E:18.6 | 3qxvA-5o04E:65.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5o8f | NANOBODY NB25 (Lama glama) |
no annotation | 6 | MET L 34ARG L 72ASN L 74VAL L 79ALA L 98TYR L 114 | None | 0.64A | 3qxvA-5o8fL:21.6 | 3qxvA-5o8fL:68.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ovw | NANOBODY (Lama glama) |
no annotation | 5 | ALA G 46ARG G 94ASN G 96VAL G 101ALA G 120 | None | 0.53A | 3qxvA-5ovwG:21.5 | 3qxvA-5ovwG:59.57 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5uk4 | ANTI-VESICULARSTOMATITIS VIRUS NVHH (Vicugna pacos) |
no annotation | 7 | VAL p 2MET p 34ARG p 72ASN p 74VAL p 79ALA p 98TYR p 114 | None | 0.65A | 3qxvA-5uk4p:21.3 | 3qxvA-5uk4p:71.43 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5vaq | NB914 (Lama glama) |
no annotation | 6 | ALA B 24SER B 30ARG B 72ASN B 74VAL B 79ALA B 98 | None | 1.02A | 3qxvA-5vaqB:22.8 | 3qxvA-5vaqB:75.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5vxj | SINGLE-DOMAINANTIBODY JMK-E3 (Vicugna pacos) |
no annotation | 6 | VAL B 2MET B 34ARG B 72ASN B 74VAL B 79ALA B 98 | None | 0.72A | 3qxvA-5vxjB:19.3 | 3qxvA-5vxjB:63.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5vxj | SINGLE-DOMAINANTIBODY JMK-E3 (Vicugna pacos) |
no annotation | 6 | VAL B 2MET B 34ARG B 72VAL B 79ALA B 98TYR B 108 | None | 0.82A | 3qxvA-5vxjB:19.3 | 3qxvA-5vxjB:63.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5vxl | SINGLE-DOMAINANTIBODY JPS-G3 (Vicugna pacos) |
no annotation | 7 | ALA B 24MET B 34ARG B 73ASN B 75VAL B 80ALA B 99TYR B 106 | None | 0.68A | 3qxvA-5vxlB:20.2 | 3qxvA-5vxlB:66.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wb1 | ENVELOPE PROTEINUS28, NANOBODY 7FUSION PROTEIN (Humanbetaherpesvirus5;Lama glama) |
no annotation | 7 | VAL A1002ALA A1024MET A1034ASN A1073VAL A1078ALA A1097TYR A1107 | None | 0.97A | 3qxvA-5wb1A:18.0 | 3qxvA-5wb1A:15.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5y9f | HEAVY CHAIN OF FABFRAGMENT OF ANTIBODY28F10 (Mus musculus) |
no annotation | 6 | VAL L 2ALA L 24MET L 34ARG L 72ASN L 74TYR L 112 | None | 0.93A | 3qxvA-5y9fL:20.1 | 3qxvA-5y9fL:57.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yy5 | - (-) |
no annotation | 6 | VAL C 2ALA C 24MET C 34ARG C 71ASN C 73TYR C 97 | None | 0.92A | 3qxvA-5yy5C:19.4 | 3qxvA-5yy5C:undetectable | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6apq | ANTI-MARBURGVIRUSNUCLEOPROTEIN SINGLEDOMAIN ANTIBODY B (Lama glama) |
no annotation | 6 | VAL A 2ALA A 24ARG A 71ASN A 73VAL A 78TYR A 107 | None CL A 202 ( 4.0A)NoneNoneNoneNone | 1.19A | 3qxvA-6apqA:19.2 | 3qxvA-6apqA:66.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c9w | - (-) |
no annotation | 6 | VAL B 2ALA B 24MET B 34ASN B 74VAL B 79TYR B 114 | None | 1.17A | 3qxvA-6c9wB:21.1 | 3qxvA-6c9wB:undetectable | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6d11 | 1450 ANTIBODY, HEAVYCHAIN (Homo sapiens) |
no annotation | 5 | VAL A 2MET A 34ARG A 71ASN A 73VAL A 78 | None | 0.51A | 3qxvA-6d11A:20.4 | 3qxvA-6d11A:44.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dbe | NANOBODY VHH R303 (Lama glama) |
no annotation | 6 | SER A 30MET A 34ARG A 72VAL A 79ALA A 98TYR A 107 | None | 1.26A | 3qxvA-6dbeA:20.6 | 3qxvA-6dbeA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dbe | NANOBODY VHH R303 (Lama glama) |
no annotation | 6 | VAL A 2ALA A 24MET A 34ASN A 74ALA A 98TYR A 107 | None | 1.13A | 3qxvA-6dbeA:20.6 | 3qxvA-6dbeA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dbe | NANOBODY VHH R303 (Lama glama) |
no annotation | 6 | VAL A 2ALA A 24MET A 34VAL A 79ALA A 98TYR A 107 | None | 0.81A | 3qxvA-6dbeA:20.6 | 3qxvA-6dbeA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dbe | NANOBODY VHH R303 (Lama glama) |
no annotation | 6 | VAL A 2SER A 30MET A 34VAL A 79ALA A 98TYR A 107 | None | 1.01A | 3qxvA-6dbeA:20.6 | 3qxvA-6dbeA:undetectable | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6ehg | HC3NB1 (Lama glama) |
no annotation | 7 | ALA C 24MET C 34ARG C 72ASN C 74VAL C 79ALA C 98TYR C 112 | None | 0.71A | 3qxvA-6ehgC:22.2 | 3qxvA-6ehgC:57.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gzp | NANOBODY (Lama glama) |
no annotation | 7 | VAL A 2ALA A 24MET A 34ARG A 71ASN A 73ALA A 94TYR A 102 | None | 0.71A | 3qxvA-6gzpA:21.6 | 3qxvA-6gzpA:undetectable | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 8fab | IGG1-LAMBDA HIL FAB(HEAVY CHAIN) (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 6 | VAL B 2ALA B 24MET B 34ARG B 72ASN B 74TYR B 110 | None | 1.02A | 3qxvA-8fabB:21.7 | 3qxvA-8fabB:59.52 |