SIMILAR PATTERNS OF AMINO ACIDS FOR 3QEO_B_LLTB261

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1br2 MYOSIN

(Gallus gallus) 		PF00063
(Myosin_head)
PF02736
(Myosin_N) 		4 LEU A 705
GLN A 490
PHE A 493
LEU A 519
 None
 0.98A 3qeoB-1br2A:
1.6		 3qeoB-1br2A:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cz3 DIHYDROFOLATE
REDUCTASE

(Thermotoga
maritima) 		PF00186
(DHFR_1) 		4 VAL A 163
LEU A 143
PHE A   5
LEU A   7
 None
 1.06A 3qeoB-1cz3A:
2.2		 3qeoB-1cz3A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e3d [NIFE] HYDROGENASE
LARGE SUBUNIT

(Desulfovibrio
desulfuricans) 		PF00374
(NiFeSe_Hases) 		4 LEU B 206
TYR B 202
PHE B 167
LEU B 164
 None
 0.82A 3qeoB-1e3dB:
undetectable		 3qeoB-1e3dB:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e4o MALTODEXTRIN
PHOSPHORYLASE

(Escherichia
coli) 		PF00343
(Phosphorylase) 		4 GLU A 663
VAL A 662
LEU A 657
LEU A 427
 None
 0.92A 3qeoB-1e4oA:
2.0		 3qeoB-1e4oA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ewr DNA MISMATCH REPAIR
PROTEIN MUTS

(Thermus
aquaticus) 		PF00488
(MutS_V)
PF05188
(MutS_II)
PF05190
(MutS_IV)
PF05192
(MutS_III) 		4 VAL A 646
LEU A 650
PHE A 693
LEU A 578
 None
 1.06A 3qeoB-1ewrA:
2.3		 3qeoB-1ewrA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hlg LIPASE, GASTRIC

(Homo sapiens) 		PF00561
(Abhydrolase_1) 		4 GLU A 230
VAL A 226
LEU A 222
LEU A 325
 None
 0.87A 3qeoB-1hlgA:
2.2		 3qeoB-1hlgA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN

(Gallus gallus) 		PF00063
(Myosin_head)
PF00612
(IQ)
PF01576
(Myosin_tail_1)
PF02736
(Myosin_N) 		4 LEU S 705
GLN S 490
PHE S 493
LEU S 519
 None
 0.87A 3qeoB-1i84S:
undetectable		 3qeoB-1i84S:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum) 		PF13202
(EF-hand_5) 		4 VAL A 179
LEU A 148
PHE A 160
LEU A 161
 None
 1.02A 3qeoB-1ij5A:
undetectable		 3qeoB-1ij5A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nne DNA MISMATCH REPAIR
PROTEIN MUTS

(Thermus
aquaticus) 		PF00488
(MutS_V)
PF01624
(MutS_I)
PF05188
(MutS_II)
PF05190
(MutS_IV)
PF05192
(MutS_III) 		4 VAL A 646
LEU A 650
PHE A 693
LEU A 578
 None
 1.06A 3qeoB-1nneA:
undetectable		 3qeoB-1nneA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1psq PROBABLE THIOL
PEROXIDASE

(Streptococcus
pneumoniae) 		PF08534
(Redoxin) 		4 VAL A  80
LEU A  27
PHE A 130
LEU A 132
 None
 1.01A 3qeoB-1psqA:
undetectable		 3qeoB-1psqA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)

(Homo sapiens) 		PF00753
(Lactamase_B)
PF16123
(HAGH_C) 		4 GLU A 174
LEU A 180
TYR A 221
LEU A 136
 None
 1.03A 3qeoB-1qh5A:
undetectable		 3qeoB-1qh5A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w27 PHENYLALANINE
AMMONIA-LYASE 1

(Petroselinum
crispum) 		PF00221
(Lyase_aromatic) 		4 VAL A 259
LEU A 138
GLN A 131
LEU A 130
 None
 0.93A 3qeoB-1w27A:
undetectable		 3qeoB-1w27A:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x3o ACYL CARRIER PROTEIN

(Thermus
thermophilus) 		PF00550
(PP-binding) 		4 VAL A  13
LEU A  45
PHE A  53
LEU A  55
 None
 0.96A 3qeoB-1x3oA:
undetectable		 3qeoB-1x3oA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT

(Homo sapiens) 		PF00326
(Peptidase_S9)
PF00930
(DPPIV_N) 		4 VAL A 647
LEU A 744
TYR A 745
LEU A 537
 None
 0.95A 3qeoB-1z68A:
2.4		 3qeoB-1z68A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT

(Homo sapiens) 		PF00326
(Peptidase_S9)
PF00930
(DPPIV_N) 		4 VAL A 647
LEU A 744
TYR A 745
LEU A 752
 None
 1.04A 3qeoB-1z68A:
2.4		 3qeoB-1z68A:
16.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2a30 DEOXYCYTIDINE KINASE

(Homo sapiens) 		PF01712
(dNK) 		4 GLU A  53
GLN A  97
PHE A 137
LEU A 141
 DCZ  A 302 (-3.0A)
DCZ  A 302 (-3.2A)
DCZ  A 302 (-3.8A)
None
 0.76A 3qeoB-2a30A:
33.1		 3qeoB-2a30A:
92.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2a30 DEOXYCYTIDINE KINASE

(Homo sapiens) 		PF01712
(dNK) 		4 GLU A  53
LEU A  82
PHE A 137
LEU A 141
 DCZ  A 302 (-3.0A)
DCZ  A 302 ( 4.9A)
DCZ  A 302 (-3.8A)
None
 0.99A 3qeoB-2a30A:
33.1		 3qeoB-2a30A:
92.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e63 KIAA1787 PROTEIN

(Homo sapiens) 		PF07177
(Neuralized) 		4 VAL A  17
LEU A 160
PHE A  81
LEU A  88
 None
 0.93A 3qeoB-2e63A:
undetectable		 3qeoB-2e63A:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2es4 LIPASE CHAPERONE

(Burkholderia
glumae) 		PF03280
(Lipase_chap) 		4 LEU D 139
TYR D 135
GLN D  96
LEU D  93
 None
None
None
CSO  D  92 ( 4.3A)
 0.96A 3qeoB-2es4D:
undetectable		 3qeoB-2es4D:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2icw T-CELL RECEPTOR BETA
CHAIN V

(Mus musculus) 		PF07686
(V-set) 		4 GLU J  17
VAL J  19
LEU J  21
TYR J  89
 None
 1.06A 3qeoB-2icwJ:
undetectable		 3qeoB-2icwJ:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ja2 GLUTAMYL-TRNA
SYNTHETASE

(Mycobacterium
tuberculosis) 		PF00749
(tRNA-synt_1c) 		4 VAL A 250
LEU A 287
TYR A 283
LEU A 267
 CL  A1487 (-4.1A)
None
None
None
 1.02A 3qeoB-2ja2A:
undetectable		 3qeoB-2ja2A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mex PROTEIN PRGI

(Salmonella
enterica) 		PF09392
(T3SS_needle_F) 		4 LEU A  31
TYR A  47
GLN A  24
LEU A  23
 None
 0.94A 3qeoB-2mexA:
undetectable		 3qeoB-2mexA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o3f PUTATIVE HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YBBH

(Bacillus
subtilis) 		PF01418
(HTH_6) 		4 VAL A  72
LEU A   6
PHE A  65
LEU A  56
 MLY  A  69 ( 4.0A)
None
MLY  A  69 (-3.9A)
None
 0.99A 3qeoB-2o3fA:
undetectable		 3qeoB-2o3fA:
15.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ocp DEOXYGUANOSINE
KINASE

(Homo sapiens) 		PF01712
(dNK) 		5 LEU A  96
TYR A 100
GLN A 111
PHE A 151
LEU A 155
 DTP  A 301 (-4.6A)
DTP  A 301 (-4.5A)
DTP  A 301 (-2.9A)
DTP  A 301 (-3.3A)
None
 0.83A 3qeoB-2ocpA:
30.4		 3qeoB-2ocpA:
43.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p14 HETERODIMERIC
RESTRICTION
ENDONUCLEASE
R.BSPD6I SMALL
SUBUNIT

(Bacillus sp. D6) 		PF09491
(RE_AlwI) 		4 VAL A 142
LEU A   5
TYR A   8
PHE A  29
 None
 0.92A 3qeoB-2p14A:
undetectable		 3qeoB-2p14A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r7m 5-FORMAMINOIMIDAZOLE
-4-CARBOXAMIDE-1-(BE
TA)-D-RIBOFURANOSYL
5'-MONOPHOSPHATE
SYNTHETASE

(Methanocaldococcus
jannaschii) 		PF06849
(DUF1246)
PF06973
(DUF1297) 		4 VAL A 271
LEU A 222
TYR A 328
PHE A 207
 None
 1.06A 3qeoB-2r7mA:
undetectable		 3qeoB-2r7mA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vkc NEDD4-BINDING
PROTEIN 2

(Homo sapiens) 		PF01713
(Smr) 		4 VAL A1767
LEU A1750
TYR A1749
LEU A1693
 None
 0.90A 3qeoB-2vkcA:
undetectable		 3qeoB-2vkcA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vy8 POLYMERASE BASIC
PROTEIN 2

(Influenza A
virus) 		PF00604
(Flu_PB2) 		4 VAL A 638
LEU A 546
TYR A 550
GLN A 581
 None
 0.75A 3qeoB-2vy8A:
undetectable		 3qeoB-2vy8A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w5f ENDO-1,4-BETA-XYLANA
SE Y

(Ruminiclostridium
thermocellum) 		PF00331
(Glyco_hydro_10)
PF02018
(CBM_4_9) 		4 VAL A 498
LEU A 446
TYR A 442
PHE A 483
 None
 1.06A 3qeoB-2w5fA:
undetectable		 3qeoB-2w5fA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xhc TRANSCRIPTION
ANTITERMINATION
PROTEIN NUSG

(Thermotoga
maritima) 		PF00467
(KOW)
PF02357
(NusG) 		4 GLU A 189
VAL A 190
LEU A 196
TYR A 172
 None
 1.03A 3qeoB-2xhcA:
undetectable		 3qeoB-2xhcA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xy2 NEURAL CELL ADHESION
MOLECULE 2

(Homo sapiens) 		PF07679
(I-set) 		4 VAL A  67
LEU A  78
TYR A  91
LEU A  32
 None
 1.02A 3qeoB-2xy2A:
undetectable		 3qeoB-2xy2A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zqp PREPROTEIN
TRANSLOCASE SECY
SUBUNIT

(Thermus
thermophilus) 		PF00344
(SecY) 		4 VAL Y  39
LEU Y 135
GLN Y 161
LEU Y  75
 None
 0.93A 3qeoB-2zqpY:
undetectable		 3qeoB-2zqpY:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ail 303AA LONG
HYPOTHETICAL
ESTERASE

(Sulfurisphaera
tokodaii) 		PF07859
(Abhydrolase_3) 		4 VAL A 276
LEU A  92
TYR A  75
LEU A 296
 None
 1.01A 3qeoB-3ailA:
2.4		 3qeoB-3ailA:
25.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ff4 UNCHARACTERIZED
PROTEIN

(Cytophaga
hutchinsonii) 		PF13380
(CoA_binding_2) 		4 VAL A  56
LEU A  78
TYR A  74
LEU A  61
 None
 0.94A 3qeoB-3ff4A:
undetectable		 3qeoB-3ff4A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g5b NETRIN RECEPTOR
UNC5B

(Rattus
norvegicus) 		PF00531
(Death)
PF00791
(ZU5)
PF17217
(UPA) 		4 GLU A 740
VAL A 739
TYR A 710
LEU A 758
 None
 0.95A 3qeoB-3g5bA:
undetectable		 3qeoB-3g5bA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3icq EXPORTIN-T

(Schizosaccharomyces
pombe) 		PF08389
(Xpo1) 		4 VAL T 307
LEU T 328
TYR T 329
LEU T 381
 None
 1.05A 3qeoB-3icqT:
undetectable		 3qeoB-3icqT:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ixr BACTERIOFERRITIN
COMIGRATORY PROTEIN

(Xylella
fastidiosa) 		PF00578
(AhpC-TSA) 		4 VAL A  93
LEU A  69
TYR A  29
LEU A   7
 None
 1.05A 3qeoB-3ixrA:
undetectable		 3qeoB-3ixrA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j04 MYOSIN-11

(Gallus gallus) 		PF00063
(Myosin_head)
PF00612
(IQ)
PF01576
(Myosin_tail_1)
PF02736
(Myosin_N) 		4 LEU A 705
GLN A 490
PHE A 493
LEU A 519
 None
 0.93A 3qeoB-3j04A:
undetectable		 3qeoB-3j04A:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j9d OUTER CAPSID PROTEIN
VP2

(Bluetongue
virus) 		PF00898
(Orbi_VP2) 		4 LEU A 842
TYR A 843
GLN A 585
LEU A 850
 None
 1.03A 3qeoB-3j9dA:
undetectable		 3qeoB-3j9dA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jbh MYOSIN 2 HEAVY CHAIN
STRIATED MUSCLE

(Aphonopelma) 		PF00063
(Myosin_head)
PF01576
(Myosin_tail_1)
PF02736
(Myosin_N) 		4 LEU A 695
GLN A 483
PHE A 486
LEU A 512
 None
 0.90A 3qeoB-3jbhA:
undetectable		 3qeoB-3jbhA:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jsj PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Streptomyces
avermitilis) 		PF00440
(TetR_N) 		4 GLU A 111
VAL A 108
LEU A  59
LEU A  33
 None
 0.97A 3qeoB-3jsjA:
undetectable		 3qeoB-3jsjA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k8k ALPHA-AMYLASE, SUSG

(Bacteroides
thetaiotaomicron) 		PF00128
(Alpha-amylase) 		4 LEU A  92
TYR A  64
GLN A 581
LEU A 588
 None
 0.96A 3qeoB-3k8kA:
undetectable		 3qeoB-3k8kA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kd8 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE

(Thermoplasma
acidophilum) 		PF01676
(Metalloenzyme)
PF10143
(PhosphMutase) 		4 VAL A 220
LEU A 191
TYR A 190
LEU A 154
 None
 1.00A 3qeoB-3kd8A:
undetectable		 3qeoB-3kd8A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3khw POLYMERASE PB2

(Influenza A
virus) 		PF00604
(Flu_PB2) 		4 VAL A 638
LEU A 546
TYR A 550
GLN A 581
 None
 0.82A 3qeoB-3khwA:
undetectable		 3qeoB-3khwA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nz4 PHENYLALANINE
AMMONIA-LYASE

(Taxus
canadensis) 		PF00221
(Lyase_aromatic) 		4 VAL A 230
LEU A 108
GLN A 101
LEU A 100
 None
 0.99A 3qeoB-3nz4A:
undetectable		 3qeoB-3nz4A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3odc POLY [ADP-RIBOSE]
POLYMERASE 1

(Homo sapiens) 		PF00645
(zf-PARP) 		4 VAL A 137
LEU A 187
GLN A 198
LEU A 199
 None
 0.98A 3qeoB-3odcA:
undetectable		 3qeoB-3odcA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3okf 3-DEHYDROQUINATE
SYNTHASE

(Vibrio cholerae) 		PF01761
(DHQ_synthase) 		4 GLU A 238
VAL A 234
GLN A 163
PHE A 161
 None
 0.95A 3qeoB-3okfA:
undetectable		 3qeoB-3okfA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opy 6-PHOSPHOFRUCTO-1-KI
NASE BETA-SUBUNIT

(Komagataella
pastoris) 		PF00365
(PFK) 		4 VAL B 928
LEU B 483
TYR B 480
PHE B 924
 None
 1.00A 3qeoB-3opyB:
undetectable		 3qeoB-3opyB:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oxn PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY

(Vibrio
parahaemolyticus) 		PF03466
(LysR_substrate) 		4 VAL A 190
LEU A 282
TYR A 210
LEU A 194
 None
 1.01A 3qeoB-3oxnA:
undetectable		 3qeoB-3oxnA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pei CYTOSOL
AMINOPEPTIDASE

(Francisella
tularensis) 		PF00883
(Peptidase_M17)
PF02789
(Peptidase_M17_N) 		4 VAL A 296
LEU A 474
TYR A 473
LEU A 357
 None
 1.04A 3qeoB-3peiA:
undetectable		 3qeoB-3peiA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t4j HISTIDINE KINASE 4

(Arabidopsis
thaliana) 		PF03924
(CHASE) 		4 VAL A 241
LEU A 251
GLN A 181
PHE A 184
 None
ZIP  A 400 (-4.7A)
None
None
 1.04A 3qeoB-3t4jA:
undetectable		 3qeoB-3t4jA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wo9 VARIABLE LYMPHOCYTE
RECEPTOR C

(Lethenteron
camtschaticum) 		PF01462
(LRRNT)
PF13855
(LRR_8) 		4 VAL A 177
LEU A 208
PHE A 158
LEU A 188
 None
 1.04A 3qeoB-3wo9A:
undetectable		 3qeoB-3wo9A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bgb PUTATIVE SUGAR
KINASE MK0840

(Methanopyrus
kandleri) 		PF03702
(AnmK) 		4 VAL A 135
LEU A 333
TYR A 152
GLN A  44
 None
None
None
GOL  A1355 (-4.0A)
 1.05A 3qeoB-4bgbA:
undetectable		 3qeoB-4bgbA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c3o HYDROGENASE-1 LARGE
SUBUNIT

(Salmonella
enterica) 		PF00374
(NiFeSe_Hases) 		4 LEU A 210
TYR A 206
PHE A 173
LEU A 170
 None
 0.96A 3qeoB-4c3oA:
undetectable		 3qeoB-4c3oA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4exp MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR

(Mus musculus) 		PF00047
(ig) 		4 VAL X 101
LEU X  99
TYR X  82
LEU X 111
 None
 1.00A 3qeoB-4expX:
undetectable		 3qeoB-4expX:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fm9 DNA TOPOISOMERASE
2-ALPHA

(Homo sapiens) 		PF00521
(DNA_topoisoIV)
PF01751
(Toprim)
PF16898
(TOPRIM_C) 		4 VAL A 514
LEU A 531
TYR A 522
PHE A 556
 None
 1.02A 3qeoB-4fm9A:
3.2		 3qeoB-4fm9A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h5g AMINO ACID ABC
SUPERFAMILY ATP
BINDING CASSETTE
TRANSPORTER, BINDING
PROTEIN

(Streptococcus
pneumoniae) 		PF00497
(SBP_bac_3) 		4 GLU A  79
VAL A 246
LEU A 250
TYR A 259
 EDO  A 309 (-3.5A)
None
None
None
 1.06A 3qeoB-4h5gA:
undetectable		 3qeoB-4h5gA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hyv PYRUVATE KINASE 1

(Trypanosoma
brucei) 		PF00224
(PK)
PF02887
(PK_C) 		4 GLU A 455
VAL A 458
LEU A 398
GLN A 492
 None
 1.05A 3qeoB-4hyvA:
undetectable		 3qeoB-4hyvA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jvw IG MU CHAIN C REGION
SECRETED FORM

(Mus musculus) 		PF07654
(C1-set) 		4 LEU A 521
TYR A 534
GLN A 463
LEU A 464
 None
 0.99A 3qeoB-4jvwA:
undetectable		 3qeoB-4jvwA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kem MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Azospirillum
lipoferum) 		PF13378
(MR_MLE_C) 		4 VAL A 211
LEU A 234
PHE A 217
LEU A 252
 None
 1.03A 3qeoB-4kemA:
undetectable		 3qeoB-4kemA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m7e PROTEIN
BRASSINOSTEROID
INSENSITIVE 1

(Arabidopsis
thaliana) 		PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF12799
(LRR_4)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 VAL A  74
LEU A  98
PHE A  64
LEU A  52
 None
 1.05A 3qeoB-4m7eA:
undetectable		 3qeoB-4m7eA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o01 BACTERIOPHYTOCHROME

(Deinococcus
radiodurans) 		PF00360
(PHY)
PF01590
(GAF)
PF08446
(PAS_2) 		4 GLU A 320
VAL A 316
LEU A 312
LEU A 283
 None
 0.96A 3qeoB-4o01A:
undetectable		 3qeoB-4o01A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q69 PUTATIVE LIPOPROTEIN

(Bacteroides
thetaiotaomicron) 		PF12771
(SusD-like_2) 		4 GLU A 354
TYR A 343
GLN A 431
LEU A 421
 None
 1.01A 3qeoB-4q69A:
2.3		 3qeoB-4q69A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qxe LEUCINE-RICH
REPEAT-CONTAINING
G-PROTEIN COUPLED
RECEPTOR 4, LINKER,
VARIABLE LYMPHOCYTE
RECEPTOR B

(Eptatretus
burgeri;
Homo sapiens) 		PF01462
(LRRNT)
PF11921
(DUF3439)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 VAL A 404
LEU A 435
PHE A 385
LEU A 412
 None
 1.03A 3qeoB-4qxeA:
undetectable		 3qeoB-4qxeA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r9v SIALYLTRANSFERASE
0160

(Photobacterium
damselae) 		PF11477
(PM0188) 		4 VAL A 202
LEU A 226
TYR A 286
LEU A 237
 None
 0.78A 3qeoB-4r9vA:
undetectable		 3qeoB-4r9vA:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tr2 SUBTILISIN-LIKE 1
SERINE PROTEASE

(Plasmodium
vivax) 		PF00082
(Peptidase_S8) 		4 VAL A 127
LEU A 186
TYR A 182
LEU A  47
 None
 0.95A 3qeoB-4tr2A:
undetectable		 3qeoB-4tr2A:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u2n ZINC FINGER AND BTB
DOMAIN-CONTAINING
PROTEIN 17,NUCLEUS
ACCUMBENS-ASSOCIATED
PROTEIN 1

(Homo sapiens) 		PF00651
(BTB) 		4 VAL A  60
LEU A  52
TYR A  48
LEU A  70
 None
 0.93A 3qeoB-4u2nA:
undetectable		 3qeoB-4u2nA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u9i PERIPLASMIC [NIFE]
HYDROGENASE LARGE
SUBUNIT

(Desulfovibrio
vulgaris) 		PF00374
(NiFeSe_Hases) 		4 LEU L 216
TYR L 212
PHE L 177
LEU L 174
 None
 0.98A 3qeoB-4u9iL:
undetectable		 3qeoB-4u9iL:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uuy VACUOLAR MEMBRANE
PROTEIN PEP3

(Saccharomyces
cerevisiae) 		PF05131
(Pep3_Vps18) 		4 VAL A 343
LEU A 347
GLN A 284
LEU A 207
 None
 0.96A 3qeoB-4uuyA:
undetectable		 3qeoB-4uuyA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v2i ESTERASE/LIPASE

(Thalassospira
sp. GB04J01) 		PF07859
(Abhydrolase_3) 		4 VAL A 288
LEU A  99
TYR A  82
LEU A 310
 None
 1.05A 3qeoB-4v2iA:
undetectable		 3qeoB-4v2iA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wrl MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR

(Homo sapiens) 		PF00047
(ig) 		4 VAL A 101
LEU A  99
TYR A  82
LEU A 111
 None
 0.97A 3qeoB-4wrlA:
undetectable		 3qeoB-4wrlA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xmp LIGHT CHAIN OF
ANTIBODY VRC08

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLU L  17
VAL L  19
LEU L  21
TYR L  86
 None
 0.99A 3qeoB-4xmpL:
undetectable		 3qeoB-4xmpL:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y5f BACTERIOPHYTOCHROME

(Deinococcus
radiodurans) 		PF01590
(GAF)
PF08446
(PAS_2) 		4 GLU A 320
VAL A 316
LEU A 312
LEU A 283
 None
 0.86A 3qeoB-4y5fA:
undetectable		 3qeoB-4y5fA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b0u OPLOPHORUS-LUCIFERIN
2-MONOOXYGENASE
CATALYTIC SUBUNIT

(Oplophorus
gracilirostris) 		no annotation 4 VAL A 127
LEU A  97
PHE A 151
LEU A 149
 None
 1.00A 3qeoB-5b0uA:
undetectable		 3qeoB-5b0uA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b25 CALCIUM/CALMODULIN-D
EPENDENT
3',5'-CYCLIC
NUCLEOTIDE
PHOSPHODIESTERASE 1B

(Homo sapiens) 		PF00233
(PDEase_I) 		4 VAL A 184
LEU A 180
TYR A 215
LEU A 303
 None
 0.98A 3qeoB-5b25A:
undetectable		 3qeoB-5b25A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b4c UDP-2,3-DIACYLGLUCOS
AMINE HYDROLASE

(Pseudomonas
aeruginosa) 		PF00149
(Metallophos) 		4 GLU A 108
VAL A 110
LEU A 112
TYR A  37
 None
 1.05A 3qeoB-5b4cA:
undetectable		 3qeoB-5b4cA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bjx WLAL PROTEIN

(Campylobacter
jejuni) 		no annotation 4 VAL A 391
LEU A 349
PHE A 489
LEU A 491
 None
 1.06A 3qeoB-5bjxA:
2.4		 3qeoB-5bjxA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ce9 POLYPHENOL OXIDASE

(Juglans regia) 		PF00264
(Tyrosinase)
PF12142
(PPO1_DWL) 		4 VAL A  54
LEU A 155
TYR A 156
LEU A 128
 None
 0.89A 3qeoB-5ce9A:
undetectable		 3qeoB-5ce9A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e1r 7S VICILIN

(Carya
illinoinensis) 		PF00190
(Cupin_1) 		4 VAL A 638
LEU A 492
PHE A 381
LEU A 386
 None
 0.98A 3qeoB-5e1rA:
undetectable		 3qeoB-5e1rA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e7q ACYL-COA SYNTHETASE

(Streptomyces
platensis) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 VAL A 453
LEU A 503
TYR A 500
LEU A 411
 None
 1.06A 3qeoB-5e7qA:
undetectable		 3qeoB-5e7qA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5exr DNA POLYMERASE ALPHA
SUBUNIT B

(Homo sapiens) 		PF04042
(DNA_pol_E_B)
PF08418
(Pol_alpha_B_N) 		4 VAL D 302
LEU D 272
PHE D 297
LEU D 265
 None
 1.05A 3qeoB-5exrD:
undetectable		 3qeoB-5exrD:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f84 O-GLUCOSYLTRANSFERAS
E RUMI

(Drosophila
melanogaster) 		PF05686
(Glyco_transf_90) 		4 VAL A 251
LEU A 243
PHE A 310
LEU A 333
 None
 1.06A 3qeoB-5f84A:
undetectable		 3qeoB-5f84A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5flz SPINDLE POLE BODY
COMPONENT SPC97

(Saccharomyces
cerevisiae) 		PF04130
(Spc97_Spc98) 		4 LEU A 590
GLN A 696
PHE A 700
LEU A 697
 None
 0.89A 3qeoB-5flzA:
undetectable		 3qeoB-5flzA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fmq INFLUENZA A PB2
SUBUNIT

(Influenza A
virus) 		PF00604
(Flu_PB2) 		4 VAL A 638
LEU A 546
TYR A 550
GLN A 581
 None
 0.96A 3qeoB-5fmqA:
undetectable		 3qeoB-5fmqA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gs2 REPEBODY

(Escherichia
coli) 		PF11921
(DUF3439)
PF12354
(Internalin_N)
PF13855
(LRR_8) 		4 VAL B 196
LEU B 227
PHE B 177
LEU B 207
 None
 1.06A 3qeoB-5gs2B:
undetectable		 3qeoB-5gs2B:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h5j FERREDOXIN--NADP
REDUCTASE

(Zea mays) 		PF00175
(NAD_binding_1) 		4 VAL A 178
LEU A 204
TYR A 233
LEU A 237
 None
 1.06A 3qeoB-5h5jA:
undetectable		 3qeoB-5h5jA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hcc COMPLEMENT C5

(Homo sapiens) 		PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF07677
(A2M_recep)
PF07678
(A2M_comp) 		4 GLU A1249
TYR A1124
PHE A1147
LEU A1144
 None
 1.00A 3qeoB-5hccA:
undetectable		 3qeoB-5hccA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hlb PENICILLIN-BINDING
PROTEIN 1B

(Escherichia
coli) 		PF00905
(Transpeptidase)
PF00912
(Transgly)
PF14814
(UB2H) 		4 VAL A 678
LEU A 686
TYR A 743
LEU A 511
 None
 1.03A 3qeoB-5hlbA:
undetectable		 3qeoB-5hlbA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i4e MYOSIN-14,ALPHA-ACTI
NIN A

(Dictyostelium
discoideum;
Homo sapiens) 		PF00063
(Myosin_head)
PF00435
(Spectrin)
PF02736
(Myosin_N) 		4 LEU A 716
GLN A 503
PHE A 506
LEU A 532
 None
 0.93A 3qeoB-5i4eA:
1.9		 3qeoB-5i4eA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ibo OPLOPHORUS-LUCIFERIN
2-MONOOXYGENASE
CATALYTIC SUBUNIT

(Oplophorus
gracilirostris) 		no annotation 4 VAL A 127
LEU A  97
PHE A 151
LEU A 149
 None
 0.96A 3qeoB-5iboA:
undetectable		 3qeoB-5iboA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kzs PUTATIVE CELL
SURFACE PROTEIN,
SIMILAR TO
INTERNALIN PROTEINS

(Listeria
monocytogenes) 		PF12354
(Internalin_N)
PF13855
(LRR_8) 		5 VAL A 104
LEU A 125
TYR A 149
PHE A 130
LEU A 143
 None
 1.45A 3qeoB-5kzsA:
undetectable		 3qeoB-5kzsA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lp4 PENICILLIN-BINDING
PROTEIN 2 (PBP2)

(Helicobacter
pylori) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer) 		4 GLU A 192
VAL A 166
LEU A 113
TYR A 114
 None
 0.96A 3qeoB-5lp4A:
undetectable		 3qeoB-5lp4A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lw7 ABC TRANSPORTER
ATP-BINDING PROTEIN

(Pyrococcus
abyssi) 		PF00005
(ABC_tran)
PF00037
(Fer4)
PF04068
(RLI) 		4 VAL B 207
LEU B 215
GLN B 249
LEU B 245
 None
 1.05A 3qeoB-5lw7B:
undetectable		 3qeoB-5lw7B:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nkz PEROXIN 22

(Ogataea angusta) 		no annotation 4 GLU D  89
VAL D  85
PHE D  94
LEU D  71
 None
 0.81A 3qeoB-5nkzD:
undetectable		 3qeoB-5nkzD:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u8s CELL DIVISION
CONTROL PROTEIN 45

(Saccharomyces
cerevisiae) 		PF02724
(CDC45) 		4 VAL E 148
LEU E 152
TYR E 240
LEU E 602
 None
 0.85A 3qeoB-5u8sE:
undetectable		 3qeoB-5u8sE:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v5w MAM
DOMAIN-CONTAINING
GLYCOSYLPHOSPHATIDYL
INOSITOL ANCHOR
PROTEIN 1

(Homo sapiens) 		PF13927
(Ig_3) 		4 VAL A 153
LEU A 204
TYR A 209
PHE A 231
 None
 0.98A 3qeoB-5v5wA:
undetectable		 3qeoB-5v5wA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yew MITOFUSIN-1,MITOFUSI
N-1 FUSION PROTEIN

(Homo sapiens) 		no annotation 4 VAL B  78
LEU B 176
PHE B 233
LEU B 235
 None
 0.81A 3qeoB-5yewB:
2.1		 3qeoB-5yewB:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6at7 PHENYLALANINE
AMMONIA-LYASE

(Sorghum bicolor) 		no annotation 4 VAL A 246
LEU A 124
GLN A 117
LEU A 116
 None
 0.95A 3qeoB-6at7A:
undetectable		 3qeoB-6at7A:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bms PALMITOYLTRANSFERASE

(Danio rerio) 		no annotation 4 VAL A  19
TYR A  59
PHE A 207
LEU A 211
 PLM  A1006 ( 4.9A)
None
PLM  A1006 (-4.1A)
None
 0.99A 3qeoB-6bmsA:
undetectable		 3qeoB-6bmsA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fht BACTERIOPHYTOCHROME,
ADENYLATE CYCLASE

(Deinococcus
radiodurans;
Synechocystis
sp. PCC 6803) 		no annotation 4 GLU A 320
VAL A 316
LEU A 312
LEU A 283
 None
 0.98A 3qeoB-6fhtA:
undetectable		 3qeoB-6fhtA:
15.11