SIMILAR PATTERNS OF AMINO ACIDS FOR 3Q5S_A_ACHA1289_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1bow MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR BMRR

(Bacillus
subtilis) 		PF06445
(GyrI-like) 		4 VAL A  28
TYR A  68
GLU A 134
ILE A 136
 None
 1.19A 3q5sA-1bowA:
21.3		 3q5sA-1bowA:
66.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cf5 PROTEIN
(BETA-MOMORCHARIN)

(Momordica
charantia) 		PF00161
(RIP) 		4 ASN A 180
TYR A 109
GLU A 158
ILE A 165
 None
 1.14A 3q5sA-1cf5A:
0.0		 3q5sA-1cf5A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1chk CHITOSANASE

(Streptomyces
sp. N174) 		PF01374
(Glyco_hydro_46) 		4 VAL A  18
ASN A  23
TYR A 144
ILE A  48
 None
 0.95A 3q5sA-1chkA:
0.0		 3q5sA-1chkA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gve AFLATOXIN B1
ALDEHYDE REDUCTASE
MEMBER 3

(Rattus
norvegicus) 		PF00248
(Aldo_ket_red) 		4 VAL A 163
TYR A 107
TYR A 191
GLU A  38
 None
 0.79A 3q5sA-1gveA:
0.0		 3q5sA-1gveA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h4l CELL DIVISION
PROTEIN KINASE 5

(Homo sapiens) 		PF00069
(Pkinase) 		4 VAL A  35
TYR A  15
GLU A  51
ILE A  52
 None
 1.12A 3q5sA-1h4lA:
0.0		 3q5sA-1h4lA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hwn EBULIN

(Sambucus ebulus) 		PF00161
(RIP) 		4 ASN A 187
TYR A 116
GLU A 163
ILE A 170
 None
 1.16A 3q5sA-1hwnA:
0.0		 3q5sA-1hwnA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mdc INSECT FATTY ACID
BINDING PROTEIN

(Manduca sexta) 		PF00061
(Lipocalin) 		4 VAL A  85
ASN A  88
TYR A   2
TYR A  48
 None
None
ACE  A   0 ( 4.6A)
None
 1.17A 3q5sA-1mdcA:
0.0		 3q5sA-1mdcA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o7d LYSOSOMAL
ALPHA-MANNOSIDASE
LYSOSOMAL
ALPHA-MANNOSIDASE
LYSOSOMAL
ALPHA-MANNOSIDASE

(Bos taurus;
Bos taurus;
Bos taurus) 		PF01074
(Glyco_hydro_38)
PF09261
(Alpha-mann_mid)
PF07748
(Glyco_hydro_38C) 		4 ASN B 407
TYR B 406
TYR A 165
GLU E 918
 None
 1.07A 3q5sA-1o7dB:
undetectable		 3q5sA-1o7dB:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oa3 ENDO-BETA-1-4-GLUCAN
ASE

(Trichoderma
citrinoviride) 		PF01670
(Glyco_hydro_12) 		4 VAL A 172
ASN A 177
TYR A 195
ILE A  76
 None
 1.24A 3q5sA-1oa3A:
0.0		 3q5sA-1oa3A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1orr CDP-TYVELOSE-2-EPIME
RASE

(Salmonella
enterica) 		PF16363
(GDP_Man_Dehyd) 		4 VAL A 305
ASN A 126
TYR A 153
GLU A 133
 None
CDP  A1201 (-3.3A)
None
None
 1.20A 3q5sA-1orrA:
0.0		 3q5sA-1orrA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q8y SR PROTEIN KINASE

(Saccharomyces
cerevisiae) 		PF00069
(Pkinase) 		4 ASN A 252
TYR A 570
GLU A 596
ILE A 257
 ADP  A 810 (-4.2A)
None
None
None
 0.94A 3q5sA-1q8yA:
undetectable		 3q5sA-1q8yA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qcj POKEWEED ANTIVIRAL
PROTEIN

(Phytolacca
americana) 		PF00161
(RIP) 		4 ASN A 198
TYR A 123
GLU A 176
ILE A 183
 None
APT  A 901 (-4.7A)
APT  A 901 ( 3.6A)
None
 1.06A 3q5sA-1qcjA:
undetectable		 3q5sA-1qcjA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s7g NAD-DEPENDENT
DEACETYLASE 2

(Archaeoglobus
fulgidus) 		PF02146
(SIR2) 		4 VAL A  50
ASN A  59
TYR A  45
GLU A  69
 None
 1.20A 3q5sA-1s7gA:
undetectable		 3q5sA-1s7gA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t1e KUMAMOLISIN

(Bacillus sp.
MN-32) 		PF00082
(Peptidase_S8)
PF09286
(Pro-kuma_activ) 		4 VAL A 200
TYR A 452
TYR A 204
GLU A 394
 None
 1.23A 3q5sA-1t1eA:
1.3		 3q5sA-1t1eA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tfe ELONGATION FACTOR TS

(Thermus
thermophilus) 		PF00889
(EF_TS) 		4 VAL A 154
ASN A 104
TYR A 150
GLU A 117
 None
 1.21A 3q5sA-1tfeA:
undetectable		 3q5sA-1tfeA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tr1 BETA-GLUCOSIDASE A

(Paenibacillus
polymyxa) 		PF00232
(Glyco_hydro_1) 		4 VAL A 104
TYR A 100
GLU A  22
ILE A  21
 None
 1.09A 3q5sA-1tr1A:
undetectable		 3q5sA-1tr1A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ukc ESTA

(Aspergillus
niger) 		PF00135
(COesterase) 		4 VAL A 209
TYR A 137
GLU A 443
ILE A 447
 None
 1.16A 3q5sA-1ukcA:
undetectable		 3q5sA-1ukcA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ukr ENDO-1,4-B-XYLANASE
I

(Aspergillus
niger) 		PF00457
(Glyco_hydro_11) 		4 VAL A  39
ASN A  11
TYR A  70
GLU A  79
 None
 1.19A 3q5sA-1ukrA:
undetectable		 3q5sA-1ukrA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w3i 2-KETO-3-DEOXY
GLUCONATE ALDOLASE

(Sulfolobus
solfataricus) 		PF00701
(DHDPS) 		4 VAL A  94
TYR A 128
GLU A   3
ILE A   5
 None
 1.09A 3q5sA-1w3iA:
undetectable		 3q5sA-1w3iA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wxx HYPOTHETICAL PROTEIN
TTHA1280

(Thermus
thermophilus) 		PF10672
(Methyltrans_SAM) 		4 VAL A 184
ASN A 250
TYR A 182
TYR A 113
 None
 1.16A 3q5sA-1wxxA:
undetectable		 3q5sA-1wxxA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yna ENDO-1,4-BETA-XYLANA
SE

(Thermomyces
lanuginosus) 		PF00457
(Glyco_hydro_11) 		4 VAL A  46
ASN A   5
TYR A  77
GLU A  86
 None
 1.23A 3q5sA-1ynaA:
undetectable		 3q5sA-1ynaA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yx2 AMINOMETHYLTRANSFERA
SE

(Bacillus
subtilis) 		PF01571
(GCV_T)
PF08669
(GCV_T_C) 		4 VAL A 111
ASN A 113
TYR A 198
GLU A 196
 None
 0.78A 3q5sA-1yx2A:
undetectable		 3q5sA-1yx2A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b1p MITOGEN-ACTIVATED
PROTEIN KINASE 10

(Homo sapiens) 		PF00069
(Pkinase) 		4 ASN A 152
TYR A 229
GLU A 255
ILE A 157
 AIZ  A 501 (-3.6A)
None
None
None
 1.04A 3q5sA-2b1pA:
0.3		 3q5sA-2b1pA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bp1 AFLATOXIN B1
ALDEHYDE REDUCTASE
MEMBER 2

(Homo sapiens) 		PF00248
(Aldo_ket_red) 		4 VAL A 196
TYR A 140
TYR A 224
GLU A  71
 None
 0.83A 3q5sA-2bp1A:
undetectable		 3q5sA-2bp1A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c91 AFLATOXIN B1
ALDEHYDE REDUCTASE
MEMBER 2

(Mus musculus) 		PF00248
(Aldo_ket_red) 		4 VAL A 163
TYR A 107
TYR A 191
GLU A  38
 None
 0.79A 3q5sA-2c91A:
undetectable		 3q5sA-2c91A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dvu THERMOPHILIC
REVERSIBLE
GAMMA-RESORCYLATE
DECARBOXYLASE

(Rhizobium sp.
MTP-10005) 		PF04909
(Amidohydro_2) 		4 VAL A  83
ASN A  81
GLU A  15
ILE A  76
 None
 1.10A 3q5sA-2dvuA:
undetectable		 3q5sA-2dvuA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fg9 5-NITROIMIDAZOLE
ANTIBIOTIC
RESISTANCE PROTEIN

(Bacteroides
thetaiotaomicron) 		PF12900
(Pyridox_ox_2) 		4 VAL A 143
TYR A  42
GLU A  13
ILE A  12
 None
 1.19A 3q5sA-2fg9A:
undetectable		 3q5sA-2fg9A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gq3 MALATE SYNTHASE G

(Mycobacterium
tuberculosis) 		PF01274
(Malate_synthase) 		4 ASN A 315
TYR A 320
GLU A 240
ILE A 261
 None
 1.08A 3q5sA-2gq3A:
undetectable		 3q5sA-2gq3A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j3h NADP-DEPENDENT
OXIDOREDUCTASE P1

(Arabidopsis
thaliana) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		4 VAL A 241
ASN A 270
TYR A 229
GLU A 231
 None
 1.19A 3q5sA-2j3hA:
undetectable		 3q5sA-2j3hA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jgd 2-OXOGLUTARATE
DEHYDROGENASE E1
COMPONENT

(Escherichia
coli) 		PF00676
(E1_dh)
PF02779
(Transket_pyr)
PF16870
(OxoGdeHyase_C) 		4 VAL A 564
TYR A 578
TYR A 639
ILE A 561
 None
 1.12A 3q5sA-2jgdA:
undetectable		 3q5sA-2jgdA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k4m UPF0146 PROTEIN
MTH_1000

(Methanothermobacter
thermautotrophicus) 		PF03686
(UPF0146) 		4 VAL A  50
ASN A  23
TYR A  94
ILE A  30
 None
 0.92A 3q5sA-2k4mA:
undetectable		 3q5sA-2k4mA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k5w HYPOTHETICAL
CYTOSOLIC PROTEIN
BCR103A

(Bacillus cereus) 		PF06486
(DUF1093) 		4 VAL A  13
TYR A  71
GLU A  91
ILE A  93
 None
 1.07A 3q5sA-2k5wA:
undetectable		 3q5sA-2k5wA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ock VALACYCLOVIR
HYDROLASE

(Homo sapiens) 		PF00561
(Abhydrolase_1) 		4 VAL A 151
ASN A 206
TYR A 159
ILE A 126
 None
 1.09A 3q5sA-2ockA:
undetectable		 3q5sA-2ockA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pjz HYPOTHETICAL PROTEIN
ST1066

(Sulfurisphaera
tokodaii) 		PF00005
(ABC_tran) 		4 VAL A   7
ASN A  25
TYR A  56
GLU A  66
 None
 1.18A 3q5sA-2pjzA:
undetectable		 3q5sA-2pjzA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q8w POKEWEED ANTIVIRAL
PROTEIN

(Phytolacca
acinosa) 		PF00161
(RIP) 		4 ASN A 197
TYR A 122
GLU A 175
ILE A 182
 None
 0.99A 3q5sA-2q8wA:
undetectable		 3q5sA-2q8wA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qes RIBOSOME-INACTIVATIN
G PROTEIN PD-L4

(Phytolacca
dioica) 		PF00161
(RIP) 		4 ASN A 197
TYR A 122
GLU A 175
ILE A 182
 None
ADE  A 501 (-3.7A)
ADE  A 501 ( 4.7A)
None
 1.08A 3q5sA-2qesA:
undetectable		 3q5sA-2qesA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uyy N-PAC PROTEIN

(Homo sapiens) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 VAL A 547
TYR A 551
TYR A 531
ILE A 451
 None
 1.07A 3q5sA-2uyyA:
undetectable		 3q5sA-2uyyA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2va8 SKI2-TYPE HELICASE

(Sulfolobus
solfataricus) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 VAL A 218
TYR A 237
GLU A 393
ILE A 203
 None
 0.76A 3q5sA-2va8A:
0.6		 3q5sA-2va8A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vla RESTRICTION
ENDONUCLEASE R.BPUJI

(Bacillus
pumilus) 		PF11564
(BpuJI_N) 		4 ASN A 117
TYR A 277
TYR A 216
ILE A  14
 None
 1.20A 3q5sA-2vlaA:
undetectable		 3q5sA-2vlaA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vwk DNA POLYMERASE

(Thermococcus
gorgonarius) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		4 VAL A 682
TYR A 701
GLU A 664
ILE A 666
 None
 1.00A 3q5sA-2vwkA:
undetectable		 3q5sA-2vwkA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN

(Bordetella
bronchiseptica) 		PF04183
(IucA_IucC)
PF06276
(FhuF) 		4 VAL A  29
ASN A  25
TYR A  68
GLU A 106
 None
 1.22A 3q5sA-2x0qA:
undetectable		 3q5sA-2x0qA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xka FTSZ/TUBULIN-RELATED
PROTEIN

(Bacillus
thuringiensis) 		PF00091
(Tubulin) 		4 VAL A 371
ASN A 367
TYR A 373
GLU A 250
 None
 1.21A 3q5sA-2xkaA:
0.0		 3q5sA-2xkaA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yyv PROBABLE
2-PHOSPHOSULFOLACTAT
E PHOSPHATASE

(Thermotoga
maritima) 		PF04029
(2-ph_phosp) 		4 VAL A 175
ASN A 177
TYR A 171
ILE A 182
 None
 1.07A 3q5sA-2yyvA:
undetectable		 3q5sA-2yyvA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zwi ALPHA-/BETA-GALACTOS
IDE
ALPHA-2,3-SIALYLTRAN
SFERASE

(Photobacterium
phosphoreum) 		PF11477
(PM0188) 		4 VAL A 402
ASN A 398
TYR A 376
ILE A 396
 None
 1.23A 3q5sA-2zwiA:
undetectable		 3q5sA-2zwiA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c9h ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Agrobacterium
fabrum) 		PF13416
(SBP_bac_8) 		4 VAL A  37
ASN A 273
TYR A  39
GLU A  80
 None
 0.98A 3q5sA-3c9hA:
undetectable		 3q5sA-3c9hA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3clw CONSERVED EXPORTED
PROTEIN

(Bacteroides
fragilis) 		PF14587
(Glyco_hydr_30_2) 		4 VAL A 361
TYR A 336
GLU A 340
ILE A 345
 None
 0.97A 3q5sA-3clwA:
undetectable		 3q5sA-3clwA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ctk RRNA N-GLYCOSIDASE

(Bougainvillea
spectabilis) 		PF00161
(RIP) 		4 ASN A 188
TYR A 114
GLU A 165
ILE A 172
 None
 1.10A 3q5sA-3ctkA:
undetectable		 3q5sA-3ctkA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g9v INTERLEUKIN 22
RECEPTOR, ALPHA 2

(Homo sapiens) 		PF01108
(Tissue_fac)
PF09294
(Interfer-bind) 		4 ASN A 150
TYR A 171
GLU A 164
ILE A 163
 None
 1.07A 3q5sA-3g9vA:
undetectable		 3q5sA-3g9vA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h5k RIBOSOME-INACTIVATIN
G PROTEIN
PD-L1/PD-L2

(Phytolacca
dioica) 		PF00161
(RIP) 		4 ASN A 197
TYR A 122
GLU A 175
ILE A 182
 None
EDO  A 264 (-3.5A)
None
None
 1.08A 3q5sA-3h5kA:
undetectable		 3q5sA-3h5kA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h68 SERINE/THREONINE-PRO
TEIN PHOSPHATASE 5

(Homo sapiens) 		PF00149
(Metallophos)
PF08321
(PPP5) 		4 VAL A 280
TYR A 323
TYR A 198
ILE A 212
 None
 1.21A 3q5sA-3h68A:
undetectable		 3q5sA-3h68A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i4g SUSD-LIKE
CARBOHYDRATE BINDING
PROTEIN BF1063

(Bacteroides
fragilis) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 VAL A 441
TYR A 254
GLU A 461
ILE A 464
 None
 1.06A 3q5sA-3i4gA:
undetectable		 3q5sA-3i4gA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i5t AMINOTRANSFERASE

(Rhodobacter
sphaeroides) 		PF00202
(Aminotran_3) 		4 VAL A 279
TYR A 255
GLU A 259
ILE A 284
 None
 1.05A 3q5sA-3i5tA:
undetectable		 3q5sA-3i5tA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lm6 STAGE V SPORULATION
PROTEIN AD

(Bacillus
subtilis) 		PF07451
(SpoVAD) 		4 VAL A 171
ASN A  18
TYR A 287
ILE A 182
 None
 1.14A 3q5sA-3lm6A:
1.8		 3q5sA-3lm6A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lpn RIBOSE-PHOSPHATE
PYROPHOSPHOKINASE

(Thermoplasma
volcanium) 		PF00156
(Pribosyltran)
PF13793
(Pribosyltran_N) 		4 VAL A 152
TYR A 148
TYR A 235
GLU A 257
 None
 1.15A 3q5sA-3lpnA:
undetectable		 3q5sA-3lpnA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m4f ENDO-1,4-BETA-XYLANA
SE

(Acidomyces
acidophilus) 		PF00457
(Glyco_hydro_11) 		4 VAL A  62
ASN A  36
TYR A  93
GLU A 102
 None
 1.22A 3q5sA-3m4fA:
undetectable		 3q5sA-3m4fA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o8o 6-PHOSPHOFRUCTOKINAS
E SUBUNIT ALPHA
6-PHOSPHOFRUCTOKINAS
E SUBUNIT BETA

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF00365
(PFK)
PF00365
(PFK) 		4 VAL A 860
TYR A 746
TYR B 740
ILE A 856
 None
 1.02A 3q5sA-3o8oA:
undetectable		 3q5sA-3o8oA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pqd L-LACTATE
DEHYDROGENASE

(Bacillus
subtilis) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 VAL A   8
ASN A   6
TYR A  20
ILE A 247
 None
 1.17A 3q5sA-3pqdA:
undetectable		 3q5sA-3pqdA:
25.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3q5p MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR

(Bacillus
subtilis) 		PF06445
(GyrI-like)
PF13411
(MerR_1) 		6 VAL A 147
ASN A 149
TYR A 152
TYR A 187
GLU A 253
ILE A 255
 TAC  A7101 (-4.1A)
TAC  A7101 (-3.1A)
TAC  A7101 (-4.8A)
None
TAC  A7101 (-4.2A)
TAC  A7101 (-4.2A)
 0.38A 3q5sA-3q5pA:
31.6		 3q5sA-3q5pA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qnk PUTATIVE LIPOPROTEIN

(Bacteroides
fragilis) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 VAL A 446
TYR A 248
GLU A 466
ILE A 469
 None
 1.16A 3q5sA-3qnkA:
undetectable		 3q5sA-3qnkA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vvj OVALBUMIN

(Dromaius
novaehollandiae) 		PF00079
(Serpin) 		4 VAL A 157
TYR A 180
TYR A 332
GLU A 334
 None
 1.24A 3q5sA-3vvjA:
undetectable		 3q5sA-3vvjA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3win HA3

(Clostridium
botulinum) 		PF03505
(Clenterotox) 		4 ASN E 424
TYR E 578
GLU E 540
ILE E 514
 None
 1.22A 3q5sA-3winE:
undetectable		 3q5sA-3winE:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zuz PROTEIN SHQ1

(Saccharomyces
cerevisiae) 		PF04925
(SHQ1) 		4 ASN A 487
TYR A 225
GLU A 496
ILE A 493
 IPA  A1506 (-3.3A)
None
None
None
 0.64A 3q5sA-3zuzA:
undetectable		 3q5sA-3zuzA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a45 ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN

(Clostridium
perfringens) 		PF00754
(F5_F8_type_C) 		4 ASN A1430
TYR A1395
GLU A1376
ILE A1390
 None
NGA  A2494 (-3.3A)
NGA  A2494 (-2.7A)
None
 0.92A 3q5sA-4a45A:
undetectable		 3q5sA-4a45A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b4c CHROMODOMAIN-HELICAS
E-DNA-BINDING
PROTEIN 1

(Homo sapiens) 		no annotation 4 VAL A1172
TYR A1138
GLU A1218
ILE A1215
 None
 0.85A 3q5sA-4b4cA:
undetectable		 3q5sA-4b4cA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B

(Cellvibrio
japonicus) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF16338
(DUF4968)
PF17137
(DUF5110) 		4 VAL A 675
TYR A 684
GLU A 708
ILE A 706
 None
 0.94A 3q5sA-4b9yA:
undetectable		 3q5sA-4b9yA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bob ERPP PROTEIN

(Borreliella
burgdorferi) 		PF02471
(OspE) 		4 ASN A  45
TYR A 153
GLU A 109
ILE A 141
 None
 1.14A 3q5sA-4bobA:
undetectable		 3q5sA-4bobA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cak INTEGRIN ALPHA-IIB
INTEGRIN BETA-3

(Homo sapiens;
Homo sapiens) 		PF01839
(FG-GAP)
PF08441
(Integrin_alpha2)
PF00362
(Integrin_beta)
PF07965
(Integrin_B_tail)
PF07974
(EGF_2)
PF17205
(PSI_integrin) 		4 VAL B 507
ASN B 320
TYR A 313
GLU B 475
 None
NAG  B3320 (-1.8A)
None
None
 1.14A 3q5sA-4cakB:
undetectable		 3q5sA-4cakB:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ewl 1D-MYO-INOSITOL
2-ACETAMIDO-2-DEOXY-
ALPHA-D-GLUCOPYRANOS
IDE DEACETYLASE

(Mycobacterium
tuberculosis) 		PF02585
(PIG-L) 		4 VAL A 132
TYR A  28
TYR A 181
GLU A 289
 None
 0.90A 3q5sA-4ewlA:
undetectable		 3q5sA-4ewlA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f41 PROTELOMERASE

(Agrobacterium
fabrum) 		PF16684
(Telomere_res) 		4 VAL A 130
TYR A 176
GLU A 157
ILE A 160
 None
 1.15A 3q5sA-4f41A:
undetectable		 3q5sA-4f41A:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f54 UNCHARACTERIZED
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF13590
(DUF4136) 		4 VAL A 144
TYR A 140
GLU A 156
ILE A 154
 None
 1.23A 3q5sA-4f54A:
undetectable		 3q5sA-4f54A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hfn ALLYL ALCOHOL
DEHYDROGENASE

(Nicotiana
tabacum) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		4 VAL A 239
ASN A 268
TYR A 227
GLU A 229
 None
 1.14A 3q5sA-4hfnA:
undetectable		 3q5sA-4hfnA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ily CHITOSANASE

(Streptomyces
sp. SirexAA-E) 		PF01374
(Glyco_hydro_46) 		4 VAL A  70
ASN A  75
TYR A 196
ILE A 100
 None
 1.01A 3q5sA-4ilyA:
undetectable		 3q5sA-4ilyA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m2j AMINOTRANSFERASE

(Streptomyces
lavendulae) 		PF00155
(Aminotran_1_2) 		4 VAL A 270
TYR A  77
GLU A 199
ILE A 277
 None
 1.18A 3q5sA-4m2jA:
undetectable		 3q5sA-4m2jA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m8u OLIGO-1,6-GLUCOSIDAS
E 1

(Bacillus
subtilis) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		4 VAL A 321
ASN A 324
GLU A 262
ILE A 261
 None
GOL  A 606 (-3.0A)
None
None
 1.06A 3q5sA-4m8uA:
undetectable		 3q5sA-4m8uA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oiv BILE ACID RECEPTOR

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 ASN A 297
TYR A 264
GLU A 338
ILE A 339
 None
 1.21A 3q5sA-4oivA:
undetectable		 3q5sA-4oivA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p7w L-PROLINE
CIS-4-HYDROXYLASE

(Mesorhizobium
japonicum) 		PF05118
(Asp_Arg_Hydrox)
PF05373
(Pro_3_hydrox_C) 		4 VAL A 224
ASN A 219
TYR A 220
ILE A 248
 None
 1.18A 3q5sA-4p7wA:
undetectable		 3q5sA-4p7wA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pde PROTEIN FDHD

(Escherichia
coli) 		PF02634
(FdhD-NarQ) 		4 VAL A  53
TYR A  47
GLU A  73
ILE A 132
 None
 1.15A 3q5sA-4pdeA:
undetectable		 3q5sA-4pdeA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pqg GLYCOSYLTRANSFERASE
GTF1

(Streptococcus
pneumoniae) 		PF00534
(Glycos_transf_1) 		4 VAL A 285
TYR A 427
TYR A 246
GLU A 248
 None
 1.15A 3q5sA-4pqgA:
0.0		 3q5sA-4pqgA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qqr 3,5-EPIMERASE/4-REDU
CTASE

(Arabidopsis
thaliana) 		PF04321
(RmlD_sub_bind) 		4 VAL A  64
ASN A 160
TYR A  18
ILE A 100
 None
 1.12A 3q5sA-4qqrA:
undetectable		 3q5sA-4qqrA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wgg DOUBLE BOND
REDUCTASE

(Zingiber
officinale) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		4 VAL A 246
ASN A 275
TYR A 234
GLU A 236
 None
 1.04A 3q5sA-4wggA:
undetectable		 3q5sA-4wggA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5anb ELONGATION FACTOR TU
GTP-BINDING
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF00009
(GTP_EFTU)
PF00679
(EFG_C)
PF14492
(EFG_II) 		4 ASN K 342
TYR K 305
GLU K 154
ILE K 238
 None
 1.03A 3q5sA-5anbK:
undetectable		 3q5sA-5anbK:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5awm STRESS-ACTIVATED
PROTEIN KINASE JNK

(Drosophila
melanogaster) 		PF00069
(Pkinase) 		4 ASN A 112
TYR A 189
GLU A 215
ILE A 117
 ANP  A 401 (-3.9A)
None
None
None
 1.02A 3q5sA-5awmA:
undetectable		 3q5sA-5awmA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ej3 ENDO-1,4-BETA-XYLANA
SE B

(Streptomyces
lividans) 		PF00457
(Glyco_hydro_11) 		4 VAL A  48
ASN A   7
TYR A  78
GLU A  87
 None
 1.23A 3q5sA-5ej3A:
undetectable		 3q5sA-5ej3A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fta BTB/POZ
DOMAIN-CONTAINING
ADAPTER FOR
CUL3-MEDIATED RHOA
DEGRADATION PROTEIN
3

(Homo sapiens) 		PF02214
(BTB_2) 		4 VAL A  38
TYR A  43
GLU A 111
ILE A  87
 None
 1.11A 3q5sA-5ftaA:
undetectable		 3q5sA-5ftaA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5giu PROLINE DIPEPTIDASE

(Deinococcus
radiodurans) 		PF00557
(Peptidase_M24)
PF01321
(Creatinase_N) 		4 VAL A 340
TYR A 338
GLU A 246
ILE A 313
 None
 1.10A 3q5sA-5giuA:
undetectable		 3q5sA-5giuA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gtq LUCIFERIN
REGENERATING ENZYME

(Photinus
pyralis) 		PF08450
(SGL) 		4 ASN A 160
TYR A 184
GLU A 153
ILE A 156
 MG  A 403 ( 2.6A)
None
None
None
 1.17A 3q5sA-5gtqA:
undetectable		 3q5sA-5gtqA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gv1 ENDO-1,4-BETA-XYLANA
SE

(termite gut
metagenome) 		PF00457
(Glyco_hydro_11) 		4 VAL A 176
TYR A 181
GLU A 147
ILE A 216
 None
 1.12A 3q5sA-5gv1A:
undetectable		 3q5sA-5gv1A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h8y SULFITE REDUCTASE
[FERREDOXIN],
CHLOROPLASTIC

(Zea mays) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		4 VAL A 448
ASN A 134
TYR A 137
ILE A 440
 None
 1.15A 3q5sA-5h8yA:
undetectable		 3q5sA-5h8yA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii) 		PF00150
(Cellulase) 		4 VAL A 108
ASN A  67
TYR A  66
ILE A 283
 None
 1.16A 3q5sA-5ihsA:
undetectable		 3q5sA-5ihsA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iy6 TFIIH BASAL
TRANSCRIPTION FACTOR
COMPLEX HELICASE XPB
SUBUNIT

(Homo sapiens) 		PF04851
(ResIII)
PF16203
(ERCC3_RAD25_C) 		4 VAL V 505
ASN V 656
TYR V 685
ILE V 502
 None
 1.15A 3q5sA-5iy6V:
undetectable		 3q5sA-5iy6V:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jb3 30S RIBOSOMAL
PROTEIN S2

(Pyrococcus
abyssi) 		PF00318
(Ribosomal_S2) 		4 VAL B  17
ASN B 158
TYR B  12
ILE B 154
 None
 1.19A 3q5sA-5jb3B:
undetectable		 3q5sA-5jb3B:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lnk MITOCHONDRIAL
COMPLEX I, 39 KDA
SUBUNIT

(Ovis aries) 		no annotation 4 ASN d  36
TYR d  33
TYR d 206
GLU d 316
 None
 0.95A 3q5sA-5lnkd:
undetectable		 3q5sA-5lnkd:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lnk MITOCHONDRIAL
COMPLEX I, 39 KDA
SUBUNIT

(Ovis aries) 		no annotation 4 VAL d 208
ASN d  36
TYR d 206
GLU d 316
 None
 1.12A 3q5sA-5lnkd:
undetectable		 3q5sA-5lnkd:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m4a NEUTRAL TREHALASE

(Saccharomyces
cerevisiae) 		no annotation 4 VAL A 267
TYR A 263
TYR A 226
GLU A 253
 None
 0.99A 3q5sA-5m4aA:
undetectable		 3q5sA-5m4aA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5no8 BACCELL_00875

(Bacteroides
cellulosilyticus) 		no annotation 4 VAL A 144
TYR A 127
GLU A 125
ILE A  40
 None
 1.03A 3q5sA-5no8A:
undetectable		 3q5sA-5no8A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5olt -

(-) 		no annotation 4 VAL A 538
ASN A 272
TYR A 557
ILE A 465
 None
 1.16A 3q5sA-5oltA:
undetectable		 3q5sA-5oltA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wgx FLAVIN-DEPENDENT
HALOGENASE

(Malbranchea
aurantiaca) 		PF04820
(Trp_halogenase) 		4 VAL A 204
ASN A 182
TYR A  52
ILE A 429
 None
 1.22A 3q5sA-5wgxA:
undetectable		 3q5sA-5wgxA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6axe MALATE SYNTHASE G

(Mycobacterium
marinum) 		PF01274
(Malate_synthase) 		4 ASN A 315
TYR A 320
GLU A 240
ILE A 261
 None
 1.14A 3q5sA-6axeA:
undetectable		 3q5sA-6axeA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f8z ALPHA-1,2-MANNOSIDAS
E, PUTATIVE

(Bacteroides
thetaiotaomicron) 		no annotation 4 VAL A 545
ASN A 656
TYR A 496
GLU A 494
 None
 1.13A 3q5sA-6f8zA:
undetectable		 3q5sA-6f8zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gng -

(-) 		no annotation 4 ASN A 216
TYR A 183
GLU A 144
ILE A  78
 None
 1.16A 3q5sA-6gngA:
undetectable		 3q5sA-6gngA:
undetectable